BindingDB PrimarySearch

Found 19 hits with Last Name = 'parker' and Initial = 'ej'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Anthranilate phosphoribosyltransferase (Mycobacterium tuberculosis)	BDBM93073 (ACS No 172) Show SMILES [O-]C(=O)c1ccccc1Nc1ccccc1C([O-])=O Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	1.50E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Auckland					Assay Description The initial screen was performed in a 96-well plate using the fluoresence-based assay previously described. An enzyme-coupled absorbance-based assay...				Biochemistry 52: 1776-1787 (2013) Article DOI: 10.1021/bi301387m BindingDB Entry DOI: 10.7270/Q2B56HBD
University of Auckland					More data for this Ligand-Target Pair
Phospho-2-dehydro-3-deoxyheptonate aldolase, Phe-sensitive (Escherichia coli (strain K12))	BDBM50350727 (CHEMBL1818159) Show SMILES OC(=O)C(CCCCCBr)=CP(O)(O)=O \|w:10.10\| Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	3.60E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Canterbury Curated by ChEMBL					Assay Description Competitive inhibition of recombinant Escherichia coli DAH7P synthase using PEP as substrate by Michaelis-Menten equation analysis using UV-visible s...				Bioorg Med Chem Lett 21: 5092-7 (2011) Article DOI: 10.1016/j.bmcl.2011.03.071 BindingDB Entry DOI: 10.7270/Q2KW5GDX
University of Canterbury Curated by ChEMBL					More data for this Ligand-Target Pair
Phospho-2-dehydro-3-deoxyheptonate aldolase, Phe-sensitive (Escherichia coli (strain K12))	BDBM50350723 (CHEMBL1255768 \| CHEMBL1818156) Show SMILES CC(=CP(O)(O)=O)C(O)=O \|w:2.2\| Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem Patents	Article PubMed	4.70E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Canterbury Curated by ChEMBL					Assay Description Inhibition of recombinant Escherichia coli DAH7P synthase				Bioorg Med Chem Lett 21: 5092-7 (2011) Article DOI: 10.1016/j.bmcl.2011.03.071 BindingDB Entry DOI: 10.7270/Q2KW5GDX
University of Canterbury Curated by ChEMBL					More data for this Ligand-Target Pair
Phospho-2-dehydro-3-deoxyheptonate aldolase, Phe-sensitive (Escherichia coli (strain K12))	BDBM50350725 (CHEMBL1818157 \| CHEMBL1818158) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	5.30E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Canterbury Curated by ChEMBL					Assay Description Competitive inhibition of recombinant Escherichia coli DAH7P synthase using PEP as substrate by Michaelis-Menten equation analysis using UV-visible s...				Bioorg Med Chem Lett 21: 5092-7 (2011) Article DOI: 10.1016/j.bmcl.2011.03.071 BindingDB Entry DOI: 10.7270/Q2KW5GDX
University of Canterbury Curated by ChEMBL					More data for this Ligand-Target Pair
Anthranilate phosphoribosyltransferase (Mycobacterium tuberculosis)	BDBM93074 (ACS No 142) Show SMILES Cc1cc(C)c(N)c(c1)C([O-])=O Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Similars	Article PubMed	6.30E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Auckland					Assay Description The initial screen was performed in a 96-well plate using the fluoresence-based assay previously described. An enzyme-coupled absorbance-based assay...				Biochemistry 52: 1776-1787 (2013) Article DOI: 10.1021/bi301387m BindingDB Entry DOI: 10.7270/Q2B56HBD
University of Auckland					More data for this Ligand-Target Pair
2-dehydro-3-deoxyphosphooctonate aldolase (Neisseria meningitidis serogroup B (strain MC58))	BDBM50362546 (CHEMBL1938424) Show SMILES OC(=O)C(CCCCCCOP(O)(O)=O)OP(O)(O)=O Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	7.90E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Canterbury Curated by ChEMBL					Assay Description Competitive inhibition of Neisseria meningitidis serotype B strain MC58 ATCC BAA355 KDO8P synthase expressed in Escherichia coli BL21 (DE3) cells usi...				Bioorg Med Chem Lett 22: 907-11 (2012) Article DOI: 10.1016/j.bmcl.2011.12.025 BindingDB Entry DOI: 10.7270/Q2N87B76
University of Canterbury Curated by ChEMBL					More data for this Ligand-Target Pair
Anthranilate phosphoribosyltransferase (Mycobacterium tuberculosis)	BDBM93075 (ACS No 145) Show SMILES COc1cc(N)c(cc1OC)C([O-])=O Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	1.50E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Auckland					Assay Description The initial screen was performed in a 96-well plate using the fluoresence-based assay previously described. An enzyme-coupled absorbance-based assay...				Biochemistry 52: 1776-1787 (2013) Article DOI: 10.1021/bi301387m BindingDB Entry DOI: 10.7270/Q2B56HBD
University of Auckland					More data for this Ligand-Target Pair
Anthranilate phosphoribosyltransferase (Mycobacterium tuberculosis)	BDBM93076 (ACS No 174) Show SMILES [O-]C(=O)c1ccccc1Cc1ccccc1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Similars	Article PubMed	1.80E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Auckland					Assay Description The initial screen was performed in a 96-well plate using the fluoresence-based assay previously described. An enzyme-coupled absorbance-based assay...				Biochemistry 52: 1776-1787 (2013) Article DOI: 10.1021/bi301387m BindingDB Entry DOI: 10.7270/Q2B56HBD
University of Auckland					More data for this Ligand-Target Pair
Anthranilate phosphoribosyltransferase (Mycobacterium tuberculosis)	BDBM93077 (ACS No 179) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase MCE KEGG PC cid PC sid UniChem Similars	Article PubMed	1.90E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Auckland					Assay Description The initial screen was performed in a 96-well plate using the fluoresence-based assay previously described. An enzyme-coupled absorbance-based assay...				Biochemistry 52: 1776-1787 (2013) Article DOI: 10.1021/bi301387m BindingDB Entry DOI: 10.7270/Q2B56HBD
University of Auckland					More data for this Ligand-Target Pair
Anthranilate phosphoribosyltransferase (Mycobacterium tuberculosis)	BDBM93078 (ACS No 126) Show SMILES COc1ccc(cc1N)C([O-])=O Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	6.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Auckland					Assay Description The initial screen was performed in a 96-well plate using the fluoresence-based assay previously described. An enzyme-coupled absorbance-based assay...				Biochemistry 52: 1776-1787 (2013) Article DOI: 10.1021/bi301387m BindingDB Entry DOI: 10.7270/Q2B56HBD
University of Auckland					More data for this Ligand-Target Pair
Anthranilate phosphoribosyltransferase (Mycobacterium tuberculosis)	BDBM93079 (ACS No 165) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	Article PubMed	7.90E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Auckland					Assay Description The initial screen was performed in a 96-well plate using the fluoresence-based assay previously described. An enzyme-coupled absorbance-based assay...				Biochemistry 52: 1776-1787 (2013) Article DOI: 10.1021/bi301387m BindingDB Entry DOI: 10.7270/Q2B56HBD
University of Auckland					More data for this Ligand-Target Pair
Anthranilate phosphoribosyltransferase (Mycobacterium tuberculosis)	BDBM85513 (ACS No 10 \| CAS_54-21-7 \| NSC_5900 \| Sodium salicy...) Show SMILES Oc1ccccc1C([O-])=O Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase DrugBank MCE KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	1.19E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Auckland					Assay Description The initial screen was performed in a 96-well plate using the fluoresence-based assay previously described. An enzyme-coupled absorbance-based assay...				Biochemistry 52: 1776-1787 (2013) Article DOI: 10.1021/bi301387m BindingDB Entry DOI: 10.7270/Q2B56HBD
University of Auckland					More data for this Ligand-Target Pair
Phospho-2-dehydro-3-deoxyheptonate aldolase, Phe-sensitive (Escherichia coli (strain K12))	BDBM50350725 (CHEMBL1818157 \| CHEMBL1818158) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	1.54E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Canterbury Curated by ChEMBL					Assay Description Competitive inhibition of recombinant Escherichia coli DAH7P synthase using PEP as substrate by Michaelis-Menten equation analysis using UV-visible s...				Bioorg Med Chem Lett 21: 5092-7 (2011) Article DOI: 10.1016/j.bmcl.2011.03.071 BindingDB Entry DOI: 10.7270/Q2KW5GDX
University of Canterbury Curated by ChEMBL					More data for this Ligand-Target Pair
2-dehydro-3-deoxyphosphooctonate aldolase (Neisseria meningitidis serogroup B (strain MC58))	BDBM50281349 (CHEMBL95764 \| N-(phosphonomethyl)glycine \| glyphos...) Show SMILES OC(=O)CNCP(O)(O)=O Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	2.60E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Canterbury Curated by ChEMBL					Assay Description Competitive inhibition of Neisseria meningitidis serotype B strain MC58 ATCC BAA355 KDO8P synthase expressed in Escherichia coli BL21 (DE3) cells usi...				Bioorg Med Chem Lett 22: 907-11 (2012) Article DOI: 10.1016/j.bmcl.2011.12.025 BindingDB Entry DOI: 10.7270/Q2N87B76
University of Canterbury Curated by ChEMBL					More data for this Ligand-Target Pair
Phospho-2-dehydro-3-deoxyheptonate aldolase, Phe-sensitive (Escherichia coli (strain K12))	BDBM50350723 (CHEMBL1255768 \| CHEMBL1818156) Show SMILES CC(=CP(O)(O)=O)C(O)=O \|w:2.2\| Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem Patents	Article PubMed	2.70E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Canterbury Curated by ChEMBL					Assay Description Inhibition of recombinant Escherichia coli DAH7P synthase				Bioorg Med Chem Lett 21: 5092-7 (2011) Article DOI: 10.1016/j.bmcl.2011.03.071 BindingDB Entry DOI: 10.7270/Q2KW5GDX
University of Canterbury Curated by ChEMBL					More data for this Ligand-Target Pair
2-dehydro-3-deoxyphosphooctonate aldolase (Neisseria meningitidis serogroup B (strain MC58))	BDBM50362548 (CHEMBL1941140) Show SMILES OC(CCCCCCOP(O)(O)=O)C(O)=O Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem	Article PubMed	2.70E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Canterbury Curated by ChEMBL					Assay Description Competitive inhibition of Neisseria meningitidis serotype B strain MC58 ATCC BAA355 KDO8P synthase expressed in Escherichia coli BL21 (DE3) cells usi...				Bioorg Med Chem Lett 22: 907-11 (2012) Article DOI: 10.1016/j.bmcl.2011.12.025 BindingDB Entry DOI: 10.7270/Q2N87B76
University of Canterbury Curated by ChEMBL					More data for this Ligand-Target Pair
2-dehydro-3-deoxyphosphooctonate aldolase (Neisseria meningitidis serogroup B (strain MC58))	BDBM50362544 (CHEMBL1941138) Show SMILES C[C@@H](OP(O)(O)=O)C(O)=O \|r\| Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL DrugBank MMDB PC cid PC sid PDB UniChem Similars	Article PubMed	8.70E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Canterbury Curated by ChEMBL					Assay Description Competitive inhibition of Neisseria meningitidis serotype B strain MC58 ATCC BAA355 KDO8P synthase expressed in Escherichia coli BL21 (DE3) cells usi...				Bioorg Med Chem Lett 22: 907-11 (2012) Article DOI: 10.1016/j.bmcl.2011.12.025 BindingDB Entry DOI: 10.7270/Q2N87B76
University of Canterbury Curated by ChEMBL					More data for this Ligand-Target Pair
2-dehydro-3-deoxyphosphooctonate aldolase (Neisseria meningitidis serogroup B (strain MC58))	BDBM50362547 (CHEMBL1941139) Show SMILES OCCCCCCC(OP(O)(O)=O)C(O)=O Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.00E+6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Canterbury Curated by ChEMBL					Assay Description Competitive inhibition of Neisseria meningitidis serotype B strain MC58 ATCC BAA355 KDO8P synthase expressed in Escherichia coli BL21 (DE3) cells usi...				Bioorg Med Chem Lett 22: 907-11 (2012) Article DOI: 10.1016/j.bmcl.2011.12.025 BindingDB Entry DOI: 10.7270/Q2N87B76
University of Canterbury Curated by ChEMBL					More data for this Ligand-Target Pair
2-dehydro-3-deoxyphosphooctonate aldolase (Neisseria meningitidis serogroup B (strain MC58))	BDBM50362545 (CHEMBL1235229) Show SMILES C[C@H](OP(O)(O)=O)C(O)=O \|r\| Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL KEGG MMDB PC cid PC sid PDB UniChem Similars	Article PubMed	1.20E+6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Canterbury Curated by ChEMBL					Assay Description Competitive inhibition of Neisseria meningitidis serotype B strain MC58 ATCC BAA355 KDO8P synthase expressed in Escherichia coli BL21 (DE3) cells usi...				Bioorg Med Chem Lett 22: 907-11 (2012) Article DOI: 10.1016/j.bmcl.2011.12.025 BindingDB Entry DOI: 10.7270/Q2N87B76
University of Canterbury Curated by ChEMBL					More data for this Ligand-Target Pair