| Reaction Details |
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 | Report a problem with these data |
| Target | Renin |
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| Ligand | BDBM98684 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | FRET Assay |
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| IC50 | 0.6±0.0 nM |
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| Citation |  Yokokawa, F; Ehara, T; Kawakami, S; Irie, O; Suzuki, M; Hitomi, Y; Toyao, A Organic compounds US Patent US8497286 Publication Date 7/30/2013 |
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| More Info.: | Get all data from this article, Assay Method |
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| Renin |
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| Name: | Renin |
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| Synonyms: | Angiotensinogenase | REN | RENI_HUMAN |
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| Type: | Enzyme |
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| Mol. Mass.: | 45058.99 |
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| Organism: | Homo sapiens (Human) |
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| Description: | n/a |
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| Residue: | 406 |
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| Sequence: | MDGWRRMPRWGLLLLLWGSCTFGLPTDTTTFKRIFLKRMPSIRESLKERGVDMARLGPEW
SQPMKRLTLGNTTSSVILTNYMDTQYYGEIGIGTPPQTFKVVFDTGSSNVWVPSSKCSRL
YTACVYHKLFDASDSSSYKHNGTELTLRYSTGTVSGFLSQDIITVGGITVTQMFGEVTEM
PALPFMLAEFDGVVGMGFIEQAIGRVTPIFDNIISQGVLKEDVFSFYYNRDSENSQSLGG
QIVLGGSDPQHYEGNFHYINLIKTGVWQIQMKGVSVGSSTLLCEDGCLALVDTGASYISG
STSSIEKLMEALGAKKRLFDYVVKCNEGPTLPDISFHLGGKEYTLTSADYVFQESYSSKK
LCTLAIHAMDIPPPTGPTWALGATFIRKFYTEFDRRNNRIGFALAR
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| BDBM98684 |
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| n/a |
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| Name | BDBM98684 |
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| Synonyms: | US8497286, 160 |
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| Type | Small organic molecule |
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| Emp. Form. | C27H44N4O4 |
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| Mol. Mass. | 488.6627 |
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| SMILES | CCOC[C@@H](CC(C)C)NC(=O)[C@@H]1CNC[C@@H](C1)C(=O)N(C1CC1)c1cc(OCC)c(CC)cn1 |r| |
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| Structure | 
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