| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Alpha-galactosidase |
|---|
| Ligand | BDBM50156357 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | Inhibition Assay Against Commercial Glycosidases |
|---|
| pH | 10.6±n/a |
|---|
| Temperature | 310.15±n/a K |
|---|
| IC50 | 9.49e+3±n/a nM |
|---|
| Comments | extracted |
|---|
| Citation |  Li, Z; Li, T; Dai, S; Xie, X; Ma, X; Zhao, W; Zhang, W; Li, J; Wang, PG New insights into the pharmacological chaperone activity of c2-substituted glucoimidazoles for the treatment of Gaucher disease. Chembiochem14:1239-47 (2013) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Alpha-galactosidase |
|---|
| Name: | Alpha-galactosidase |
|---|
| Synonyms: | α-galactosidase | AGAL_COFAR | Alpha-galactosidase |
|---|
| Type: | Protein |
|---|
| Mol. Mass.: | 41306.82 |
|---|
| Organism: | Coffea arabica (Coffee beans) |
|---|
| Description: | n/a |
|---|
| Residue: | 378 |
|---|
| Sequence: | MVKSPGTEDYTRRSLLANGLGLTPPMGWNSWNHFRCNLDEKLIRETADAMVSKGLAALGY
KYINLDDCWAELNRDSQGNLVPKGSTFPSGIKALADYVHSKGLKLGIYSDAGTQTCSKTM
PGSLGHEEQDAKTFASWGVDYLKYDNCNNNNISPKERYPIMSKALLNSGRSIFFSLCEWG
EEDPATWAKEVGNSWRTTGDIDDSWSSMTSRADMNDKWASYAGPGGWNDPDMLEVGNGGM
TTTEYRSHFSIWALAKAPLLIGCDIRSMDGATFQLLSNAEVIAVNQDKLGVQGNKVKTYG
DLEVWAGPLSGKRVAVALWNRGSSTATITAYWSDVGLPSTAVVNARDLWAHSTEKSVKGQ
ISAAVDAHDSKMYVLTPQ
|
|
|
|---|
| BDBM50156357 |
|---|
| n/a |
|---|
| Name | BDBM50156357 |
|---|
| Synonyms: | 2-Hydroxymethyl-1-nonyl-piperidine-3,4,5-triol | CHEMBL187158 | NN-DNJ |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C15H31NO4 |
|---|
| Mol. Mass. | 289.4109 |
|---|
| SMILES | CCCCCCCCCN1CC(O)C(O)C(O)C1CO |
|---|
| Structure | 
|
|---|
Search and Browse
