| Reaction Details |
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 | Report a problem with these data |
| Target | Sodium/glucose cotransporter 2 |
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| Ligand | BDBM109279 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Inhibition Assay |
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| IC50 | 4.58±0.0 nM |
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| Citation |  Yang, F; Tang, PC; Dong, Q; Tu, W; Fan, J; Guan, D; Shen, G; Wang, Y; Yuan, J; Zhang, L C-aryl glucoside derivatives, preparation process and pharmaceutical use thereof US Patent US8609622 Publication Date 12/17/2013 |
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| More Info.: | Get all data from this article, Assay Method |
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| Sodium/glucose cotransporter 2 |
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| Name: | Sodium/glucose cotransporter 2 |
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| Synonyms: | Low affinity sodium-glucose cotransporter | Na(+)/glucose cotransporter 2 | SC5A2_MOUSE | Sglt2 | Slc5a2 | Sodium/glucose cotransporter 2 | Solute carrier family 5 member 2 | sodium-dependent glucose cotransporter 2 (SGLT2) |
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| Type: | Protein |
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| Mol. Mass.: | 73014.31 |
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| Organism: | Mus musculus (Mouse) |
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| Description: | Q923I7 |
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| Residue: | 670 |
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| Sequence: | MEQHVEAGSELGEQKVLIDNPADILVIAAYFLLVIGVGLWSMFRTNRGTVGGYFLAGRSM
VWWPVGASLFASNIGSGHFVGLAGTGAASGLAVAGFEWNALFVVLLLGWLFVPVYLTAGV
ITMPQYLRKRFGGHRIRLYLSVLSLFLYIFTKISVDMFSGAVFIQQALGWNIYASVIALL
GITMIYTVTGGLAALMYTDTVQTFVILAGAFILTGYAFHEVGGYSGLFDKYLGAMTSLTV
SKDPSVGNISSTCYQPRPDSYHLLRDPVTGDLPWPALLLGLTIVSGWYWCSDQVIVQRCL
AGKNLTHIKAGCILCGYLKLMPMFLMVMPGMISRILYPDEVACVVPEVCKRVCGTEVGCS
NIAYPRLVVKLMPNGLRGLMLAVMLAALMSSLASIFNSSSTLFTMDIYTRLRPRAGDKEL
LLVGRLWVVFIVAVSVAWLPVVQAAQGGQLFDYIQSVSSYLAPPVSAVFVLALFVPRVNE
KGAFWGLVGGLLMGLARLIPEFFFGSGSCVRPSACPALFCRVHYLYFAIILFICSGILTL
GISLCTAPIPQKHLHRLVFSLRHSKEEREDLDADELEGPAPAPVQNGGQECAMEMEEVQS
PAPGLLRRCLLWFCGMSKSGSGSPPPTTEEVAATTRRLEDISEDPRWARVVNLNALLMMT
VAVFLWGFYA
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| BDBM109279 |
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| n/a |
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| Name | BDBM109279 |
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| Synonyms: | US8609622, 7 |
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| Type | Small organic molecule |
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| Emp. Form. | C22H22ClF3O7 |
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| Mol. Mass. | 490.854 |
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| SMILES | OC[C@]12COC(O1)([C@H](O)[C@@H](O)[C@@H]2O)c1ccc(Cl)c(Cc2ccc(OCC(F)(F)F)cc2)c1 |r| |
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| Structure | 
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