| Reaction Details |
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 | Report a problem with these data |
| Target | Metallo-beta-lactamase VIM-2 |
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| Ligand | BDBM153701 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Direct Competition Assay |
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| Ki | 1.4e+4± 1e+3 nM |
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| Citation |  Mojica, MF; Mahler, SG; Bethel, CR; Taracila, MA; Kosmopoulou, M; Papp-Wallace, KM; Llarrull, LI; Wilson, BM; Marshall, SH; Wallace, CJ; Villegas, MV; Harris, ME; Vila, AJ; Spencer, J; Bonomo, RA Exploring the Role of Residue 228 in Substrate and Inhibitor Recognition by VIM Metallo-ß-lactamases. Biochemistry54:3183-96 (2015) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Metallo-beta-lactamase VIM-2 |
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| Name: | Metallo-beta-lactamase VIM-2 |
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| Synonyms: | Beta-lactamase VIM-2 | Metallo-beta-lactamase VIM-2 (VIM-2) |
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| Type: | Protein |
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| Mol. Mass.: | 28318.00 |
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| Organism: | Pseudomonas aeruginosa (g-Proteobacteria) |
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| Description: | n/a |
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| Residue: | 266 |
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| Sequence: | MFKLLSKLLVYLTASIMAIASPLAFSVDSSGEYPTVSEIPVGEVRLYQIADGVWSHIATQ
SFDGAVYPSNGLIVRDGDELLLIDTAWGAKNTAALLAEIEKQIGLPVTRAVSTHFHDDRV
GGVDVLRAAGVATYASPSTRRLAEVEGNEIPTHSLEGLSSSGDAVRFGPVELFYPGAAHS
TDNLVVYVPSASVLYGGCAIYELSRTSAGNVADADLAEWPTSIERIQQHYPEAQFVIPGH
GLPGGLDLLKHTTNVVKAHTNRSVVE
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| BDBM153701 |
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| n/a |
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| Name | BDBM153701 |
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| Synonyms: | D-VC26 |
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| Type | Small organic molecule |
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| Emp. Form. | C9H15NO2S3 |
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| Mol. Mass. | 265.416 |
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| SMILES | CC1(C)S[C@@H]2CS[C@@H](CS)N2[C@H]1C(O)=O |r| |
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| Structure | 
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