| Reaction Details |
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 | Report a problem with these data |
| Target | MBT domain-containing protein 1 |
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| Ligand | BDBM154550 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | AlphaScreen Assay |
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| pH | 8±0 |
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| Temperature | 1937.05±0 K |
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| IC50 | 7.8e+4± 1.6e+4 nM |
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| Citation |  Perfetti, MT; Baughman, BM; Dickson, BM; Mu, Y; Cui, G; Mader, P; Dong, A; Norris, JL; Rothbart, SB; Strahl, BD; Brown, PJ; Janzen, WP; Arrowsmith, CH; Mer, G; McBride, KM; James, LI; Frye, SV Identification of a fragment-like small molecule ligand for the methyl-lysine binding protein, 53BP1. ACS Chem Biol10:1072-81 (2015) [PubMed] Article |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| MBT domain-containing protein 1 |
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| Name: | MBT domain-containing protein 1 |
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| Synonyms: | MBT domain-containing protein 1 | MBT domain-containing protein 1 (MBTD1) | MBTD1 | MBTD1_HUMAN |
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| Type: | Protein |
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| Mol. Mass.: | 70557.67 |
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| Organism: | Homo sapiens (Human) |
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| Description: | n/a |
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| Residue: | 628 |
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| Sequence: | MFDGYDSCSEDTSSSSSSEESEEEVAPLPSNLPIIKNNGQVYTYPDGKSGMATCEMCGMV
GVRDAFYSKTKRFCSVSCSRSYSSNSKKASILARLQGKPPTKKAKVLQKQPLVAKLAAYA
QYQATLQNQAKTKAAVSMEGFSWGNYINSNSFIAAPVTCFKHAPMGTCWGDISENVRVEV
PNTDCSLPTKVFWIAGIVKLAGYNALLRYEGFENDSGLDFWCNICGSDIHPVGWCAASGK
PLVPPRTIQHKYTNWKAFLVKRLTGAKTLPPDFSQKVSESMQYPFKPCMRVEVVDKRHLC
RTRVAVVESVIGGRLRLVYEESEDRTDDFWCHMHSPLIHHIGWSRSIGHRFKRSDITKKQ
DGHFDTPPHLFAKVKEVDQSGEWFKEGMKLEAIDPLNLSTICVATIRKVLADGFLMIGID
GSEAADGSDWFCYHATSPSIFPVGFCEINMIELTPPRGYTKLPFKWFDYLRETGSIAAPV
KLFNKDVPNHGFRVGMKLEAVDLMEPRLICVATVTRIIHRLLRIHFDGWEEEYDQWVDCE
SPDLYPVGWCQLTGYQLQPPASQSSRENQSASSKQKKKAKSQQYKGHKKMTTLQLKEELL
DGEDYNFLQGASDQESNGSANFYIKQEP
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| BDBM154550 |
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| n/a |
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| Name | BDBM154550 |
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| Synonyms: | 3-Bromo-N-(3-(pyrrolidin-1-yl)propyl)benzamide (6) |
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| Type | Small organic molecule |
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| Emp. Form. | C14H19BrN2O |
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| Mol. Mass. | 311.217 |
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| SMILES | Brc1cccc(c1)C(=O)NCCCN1CCCC1 |
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| Structure | 
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