| Reaction Details |
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 | Report a problem with these data |
| Target | Baculoviral IAP repeat-containing protein 2 |
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| Ligand | BDBM156136 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | In vitro Competitive Displacement Binding Assays |
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| pH | 7.5±n/a |
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| Temperature | 298.15±n/a K |
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| IC50 | 32±n/a nM |
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| Comments | extracted |
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| Citation |  Woolford, AJ; Howard, S; Buck, IM; Chessari, G; Johnson, CN; Tamanini, E; Day, JE; Chiarparin, E; Heightman, TD; Frederickson, M; Griffiths-Jones, CM Bicyclic heterocycle compounds and their uses in therapy US Patent US9018214 Publication Date 4/28/2015 |
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| More Info.: | Get all data from this article, Assay Method |
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| Baculoviral IAP repeat-containing protein 2 |
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| Name: | Baculoviral IAP repeat-containing protein 2 |
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| Synonyms: | API1 | BIRC2 | BIRC2_HUMAN | Baculoviral IAP repeat-containing protein 2 (cIAP1) | Cellular inhibitor of apoptosis 1 | Inhibitor of apoptosis protein 2 (cIAP1) | MIHB | RNF48 |
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| Type: | Protein |
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| Mol. Mass.: | 69900.47 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Q13490 |
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| Residue: | 618 |
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| Sequence: | MHKTASQRLFPGPSYQNIKSIMEDSTILSDWTNSNKQKMKYDFSCELYRMSTYSTFPAGV
PVSERSLARAGFYYTGVNDKVKCFCCGLMLDNWKLGDSPIQKHKQLYPSCSFIQNLVSAS
LGSTSKNTSPMRNSFAHSLSPTLEHSSLFSGSYSSLSPNPLNSRAVEDISSSRTNPYSYA
MSTEEARFLTYHMWPLTFLSPSELARAGFYYIGPGDRVACFACGGKLSNWEPKDDAMSEH
RRHFPNCPFLENSLETLRFSISNLSMQTHAARMRTFMYWPSSVPVQPEQLASAGFYYVGR
NDDVKCFCCDGGLRCWESGDDPWVEHAKWFPRCEFLIRMKGQEFVDEIQGRYPHLLEQLL
STSDTTGEENADPPIIHFGPGESSSEDAVMMNTPVVKSALEMGFNRDLVKQTVQSKILTT
GENYKTVNDIVSALLNAEDEKREEEKEKQAEEMASDDLSLIRKNRMALFQQLTCVLPILD
NLLKANVINKQEHDIIKQKTQIPLQARELIDTILVKGNAAANIFKNCLKEIDSTLYKNLF
VDKNMKYIPTEDVSGLSLEEQLRRLQEERTCKVCMDKEVSVVFIPCGHLVVCQECAPSLR
KCPICRGIIKGTVRTFLS
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| BDBM156136 |
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| n/a |
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| Name | BDBM156136 |
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| Synonyms: | US9018214, 187 |
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| Type | Small organic molecule |
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| Emp. Form. | C28H35N5O3 |
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| Mol. Mass. | 489.6092 |
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| SMILES | C[C@@H]1CN(CC(=O)N2CC(C)(C)c3ncc(cc23)C(=O)c2ccccc2)[C@@H](CN2CCCC2=O)CN1 |r| |
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| Structure | 
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