| Reaction Details |
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 | Report a problem with these data |
| Target | Poly [ADP-ribose] polymerase tankyrase-1 [1091-1325] |
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| Ligand | BDBM230984 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Tankyrase Biochemical Assays |
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| Temperature | 298.15±n/a K |
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| IC50 | 307±n/a nM |
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| Comments | extracted |
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| Citation |  Bregman, H; Buchanan, JL; Chakka, N; Dimauro, EF; Gunaydin, H; Guzman-Perez, A; Hua, Z; Huang, H; Huang, X; Martin, MW; Patel, VF Oxazolidinone compounds and derivatives thereof US Patent US9340549 Publication Date 5/17/2016 |
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| More Info.: | Get all data from this article, Assay Method |
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| Poly [ADP-ribose] polymerase tankyrase-1 [1091-1325] |
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| Name: | Poly [ADP-ribose] polymerase tankyrase-1 [1091-1325] |
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| Synonyms: | PARP5A | PARPL | TIN1 | TINF1 | TNKS | TNKS1 | TNKS1_HUMAN | Tankyrase-1 |
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| Type: | Enzyme |
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| Mol. Mass.: | 26714.90 |
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| Organism: | Homo sapiens (Human) |
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| Description: | O95271[1091-1325] |
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| Residue: | 235 |
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| Sequence: | QGTNPYLTFHCVNQGTILLDLAPEDKEYQSVEEEMQSTIREHRDGGNAGGIFNRYNVIRI
QKVVNKKLRERFCHRQKEVSEENHNHHNERMLFHGSPFINAIIHKGFDERHAYIGGMFGA
GIYFAENSSKSNQYVYGIGGGTGCPTHKDRSCYICHRQMLFCRVTLGKSFLQFSTMKMAH
APPGHHSVIGRPSVNGLAYAEYVIYRGEQAYPEYLITYQIMKPEAPSQTATAAEQ
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| BDBM230984 |
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| n/a |
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| Name | BDBM230984 |
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| Synonyms: | US9340549, 2 |
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| Type | Small organic molecule |
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| Emp. Form. | C27H22FN3O3 |
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| Mol. Mass. | 455.4803 |
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| SMILES | CC1(C)OC(=O)N([C@H]1c1ccc(F)cc1)c1ccc(cc1)C(=O)Nc1cccc2cccnc12 |r| |
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| Structure | 
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