| Reaction Details |
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 | Report a problem with these data |
| Target | Muscarinic acetylcholine receptor M1 |
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| Ligand | BDBM234388 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Cell-Based Functional Assay (M1) |
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| IC50 | >10000±0.0 nM |
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| Citation |  Nirogia, RV; Kambhampati, R; Daulatabad, AV; Gudla, P; Shaikh, M; Achanta, PK; Shinde, AK; Dubey, PK Design, synthesis and pharmacological evaluation of conformationally restricted N-arylsulfonyl-3-aminoalkoxy indoles as a potential 5-HT6 receptor ligands. J Enzyme Inhib Med Chem26:341-9 (2011) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Muscarinic acetylcholine receptor M1 |
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| Name: | Muscarinic acetylcholine receptor M1 |
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| Synonyms: | ACM1_HUMAN | CHRM1 | Cholinergic receptor, muscarinic 1 | Cholinergic, muscarinic M1 |
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| Type: | Protein |
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| Mol. Mass.: | 51442.54 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P11229 |
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| Residue: | 460 |
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| Sequence: | MNTSAPPAVSPNITVLAPGKGPWQVAFIGITTGLLSLATVTGNLLVLISFKVNTELKTVN
NYFLLSLACADLIIGTFSMNLYTTYLLMGHWALGTLACDLWLALDYVASNASVMNLLLIS
FDRYFSVTRPLSYRAKRTPRRAALMIGLAWLVSFVLWAPAILFWQYLVGERTVLAGQCYI
QFLSQPIITFGTAMAAFYLPVTVMCTLYWRIYRETENRARELAALQGSETPGKGGGSSSS
SERSQPGAEGSPETPPGRCCRCCRAPRLLQAYSWKEEEEEDEGSMESLTSSEGEEPGSEV
VIKMPMVDPEAQAPTKQPPRSSPNTVKRPTKKGRDRAGKGQKPRGKEQLAKRKTFSLVKE
KKAARTLSAILLAFILTWTPYNIMVLVSTFCKDCVPETLWELGYWLCYVNSTINPMCYAL
CNKAFRDTFRLLLLCRWDKRRWRKIPKRPGSVHRTPSRQC
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| BDBM234388 |
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| n/a |
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| Name | BDBM234388 |
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| Synonyms: | 3-Chloro-10-(2-N,N-Dimethylaminoethoxy)-5-Thia-4-b-azaindeno (8b) |
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| Type | Small organic molecule |
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| Emp. Form. | C18H17ClN2O3S |
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| Mol. Mass. | 376.857 |
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| SMILES | CN(C)CCOc1c2-c3ccccc3S(=O)(=O)n2c2cc(Cl)ccc12 |
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| Structure | 
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