| Reaction Details |
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 | Report a problem with these data |
| Target | Egl nine homolog 1 |
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| Ligand | BDBM242575 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Fluorescence Polarization Assay |
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| pH | 7.5±n/a |
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| IC50 | 25±n/a nM |
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| Comments | extracted |
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| Citation |  Takayama, T; Shibata, T; Shiozawa, F; Kawabe, K; Shimizu, Y; Hamada, M; Hiratate, A; Takahashi, M; Ushiyama, F; Oi, T; Shirasaki, Y; Matsuda, D; Koizumi, C; Kato, S Partially saturated nitrogen-containing heterocyclic compound US Patent US9422240 Publication Date 8/23/2016 |
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| More Info.: | Get all data from this article, Assay Method |
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| Egl nine homolog 1 |
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| Name: | Egl nine homolog 1 |
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| Synonyms: | C1orf12 | EGLN1 | EGLN1_HUMAN | Egl nine homolog 1 (EGLN1) | Hypoxia-inducible factor prolyl hydroxylase 2 (HIF-PH2) | Hypoxia-inducible factor prolyl hydroxylase 2 (HIFPH2) | Prolyl hydroxylase domain-containing protein 2 (PHD2) |
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| Type: | Protein |
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| Mol. Mass.: | 46035.59 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Q9GZT9 |
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| Residue: | 426 |
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| Sequence: | MANDSGGPGGPSPSERDRQYCELCGKMENLLRCSRCRSSFYCCKEHQRQDWKKHKLVCQG
SEGALGHGVGPHQHSGPAPPAAVPPPRAGAREPRKAAARRDNASGDAAKGKVKAKPPADP
AAAASPCRAAAGGQGSAVAAEAEPGKEEPPARSSLFQEKANLYPPSNTPGDALSPGGGLR
PNGQTKPLPALKLALEYIVPCMNKHGICVVDDFLGKETGQQIGDEVRALHDTGKFTDGQL
VSQKSDSSKDIRGDKITWIEGKEPGCETIGLLMSSMDDLIRHCNGKLGSYKINGRTKAMV
ACYPGNGTGYVRHVDNPNGDGRCVTCIYYLNKDWDAKVSGGILRIFPEGKAQFADIEPKF
DRLLFFWSDRRNPHEVQPAYATRYAITVWYFDADERARAKVKYLTGEKGVRVELNKPSDS
VGKDVF
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| BDBM242575 |
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| n/a |
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| Name | BDBM242575 |
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| Synonyms: | US9422240, 1-409 |
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| Type | Small organic molecule |
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| Emp. Form. | C21H20ClN3O6 |
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| Mol. Mass. | 445.853 |
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| SMILES | Cc1cc(CN2CCC(O)=C(C(=O)NCC(O)=O)C2=O)cnc1Oc1ccc(Cl)cc1 |t:9| |
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| Structure | 
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