Compile Data Set for Download or QSAR

Found 203 hits with Last Name = 'kawabe' and Initial = 'k'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium-dependent phosphate transport protein 2B (Rattus norvegicus)	BDBM50590497 (CHEMBL5182987) Show SMILES CCC(CC)N(CCN(C)C(=O)CCC(=O)NCCOCCOCCOCCO)Cc1cccc(c1)C(=O)Nc1sc2CC(C)(C)CCc2c1C(=O)c1cnn(c1)-c1ccc(Cl)c(c1)C(F)(F)F Show InChI	KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.10	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1016/j.bmcl.2022.128572 BindingDB Entry DOI: 10.7270/Q26977M6
					More data for this Ligand-Target Pair
Sodium-dependent phosphate transport protein 2B (Rattus norvegicus)	BDBM50596527 (CHEMBL5195035) Show SMILES CCC(CC)N(CCN(C)C(=O)CCC(=O)NC(C)(C)C(=O)NCCN(C)C)Cc1cccc(c1)C(=O)Nc1sc2CC(C)(C)CCc2c1C(=O)c1cnn(c1)-c1ccc(Cl)c(c1)C(F)(F)F Show InChI	KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	7.60	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1016/j.bmcl.2022.128572 BindingDB Entry DOI: 10.7270/Q26977M6
					More data for this Ligand-Target Pair
Sodium/glucose cotransporter 2 (Homo sapiens (Human))	BDBM50503838 (CHEMBL4450704) Show SMILES Cc1cc(C)c(cc1Cc1ccc(\C=C\C(C)(C)C(=O)NC(C)(C)CO)cc1)[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O |r| Show InChI InChI=1S/C31H43NO7/c1-18-13-19(2)23(28-27(37)26(36)25(35)24(16-33)39-28)15-22(18)14-21-9-7-20(8-10-21)11-12-30(3,4)29(38)32-31(5,6)17-34/h7-13,15,24-28,33-37H,14,16-17H2,1-6H3,(H,32,38)/b12-11+/t24-,25-,26+,27-,28+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
Taisho Pharmaceutical Co., Ltd. Curated by ChEMBL					Assay Description Inhibition of human SGLT2 expressed in CHOK1 cells assessed as reduction in sodium-dependent glucose uptake after 1 hr in presence of [14C]-methyl-al...				Bioorg Med Chem 27: 394-409 (2019) Article DOI: 10.1016/j.bmc.2018.12.015 BindingDB Entry DOI: 10.7270/Q2X63R7F
					More data for this Ligand-Target Pair
Sodium-dependent phosphate transport protein 2B (Rattus norvegicus)	BDBM50600220 (CHEMBL5177872) Show SMILES CCN([C@H]1CC[C@@H](CC1)C(O)=O)S(=O)(=O)c1cccc(c1)C(=O)Nc1ccc(nc1C(=O)Nc1ccc(CCc2ccc(cc2)C(=O)NS(=O)(=O)NC)cc1)N1CCCCC1 |r,wU:6.9,wD:3.2,(2.67,-6.93,;1.33,-6.16,;1.33,-4.62,;2.67,-3.85,;4,-4.62,;5.33,-3.85,;5.33,-2.31,;4,-1.54,;2.67,-2.31,;6.67,-1.54,;8,-2.31,;6.67,-0,;-0,-3.85,;.77,-2.52,;-.77,-2.52,;-1.33,-4.62,;-1.33,-6.16,;-2.66,-6.93,;-4,-6.17,;-4,-4.62,;-2.66,-3.85,;-5.33,-3.85,;-6.66,-4.62,;-5.33,-2.31,;-6.66,-1.54,;-8,-2.31,;-9.33,-1.54,;-9.33,-.01,;-8,.77,;-6.66,-0,;-5.33,.77,;-5.33,2.31,;-4,-0,;-2.66,.77,;-2.66,2.31,;-1.33,3.08,;-0,2.31,;1.33,3.08,;2.67,2.31,;4,3.08,;4,4.63,;5.33,5.39,;6.66,4.62,;6.67,3.09,;5.34,2.31,;8,5.39,;8,6.93,;9.33,4.62,;10.67,5.39,;11.44,6.73,;9.9,6.73,;12,4.62,;13.33,5.39,;-0,.77,;-1.33,.01,;-10.67,.76,;-12,-.01,;-13.33,.76,;-13.33,2.3,;-12,3.07,;-10.67,2.3,)| Show InChI	KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1016/j.bmcl.2022.128700 BindingDB Entry DOI: 10.7270/Q28W3JB9
					More data for this Ligand-Target Pair
Egl nine homolog 1 (Homo sapiens (Human))	BDBM242568 (US9422240, 1-378) Show SMILES CC(C)c1ccc(Oc2ccc(CN3CCC(O)=C(C(=O)NCC(O)=O)C3=O)cn2)cc1 |t:17| Show InChI InChI=1S/C23H25N3O6/c1-14(2)16-4-6-17(7-5-16)32-19-8-3-15(11-24-19)13-26-10-9-18(27)21(23(26)31)22(30)25-12-20(28)29/h3-8,11,14,27H,9-10,12-13H2,1-2H3,(H,25,30)(H,28,29)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	14	n/a	n/a	n/a	n/a	7.5	n/a
TAISHO PHARMACEUTICAL CO., LTD US Patent					Assay Description The enzyme and the substrate were each diluted with a 50 mM tris-hydrochloric acid buffer (pH 7.5) containing 12.5 mM KCl, 3.75 mM MgCl2, 25 μM ...				US Patent US9422240 (2016) BindingDB Entry DOI: 10.7270/Q24B307K
					More data for this Ligand-Target Pair
Egl nine homolog 1 (Homo sapiens (Human))	BDBM242554 (US9422240, 1-296) Show SMILES OC(=O)CNC(=O)C1=C(O)CCN(Cc2ccc(Oc3ccc(cc3)C3CC3)nc2)C1=O |c:7| Show InChI InChI=1S/C23H23N3O6/c27-18-9-10-26(23(31)21(18)22(30)25-12-20(28)29)13-14-1-8-19(24-11-14)32-17-6-4-16(5-7-17)15-2-3-15/h1,4-8,11,15,27H,2-3,9-10,12-13H2,(H,25,30)(H,28,29)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	15	n/a	n/a	n/a	n/a	7.5	n/a
TAISHO PHARMACEUTICAL CO., LTD US Patent					Assay Description The enzyme and the substrate were each diluted with a 50 mM tris-hydrochloric acid buffer (pH 7.5) containing 12.5 mM KCl, 3.75 mM MgCl2, 25 μM ...				US Patent US9422240 (2016) BindingDB Entry DOI: 10.7270/Q24B307K
					More data for this Ligand-Target Pair
Egl nine homolog 1 (Homo sapiens (Human))	BDBM242567 (US9422240, 1-377) Show SMILES CCCc1ccc(Oc2ccc(CN3CCC(O)=C(C(=O)NCC(O)=O)C3=O)cn2)cc1 |t:17| Show InChI InChI=1S/C23H25N3O6/c1-2-3-15-4-7-17(8-5-15)32-19-9-6-16(12-24-19)14-26-11-10-18(27)21(23(26)31)22(30)25-13-20(28)29/h4-9,12,27H,2-3,10-11,13-14H2,1H3,(H,25,30)(H,28,29)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	15	n/a	n/a	n/a	n/a	7.5	n/a
TAISHO PHARMACEUTICAL CO., LTD US Patent					Assay Description The enzyme and the substrate were each diluted with a 50 mM tris-hydrochloric acid buffer (pH 7.5) containing 12.5 mM KCl, 3.75 mM MgCl2, 25 μM ...				US Patent US9422240 (2016) BindingDB Entry DOI: 10.7270/Q24B307K
					More data for this Ligand-Target Pair
Sodium-dependent phosphate transport protein 2B (Homo sapiens (Human))	BDBM50590497 (CHEMBL5182987) Show SMILES CCC(CC)N(CCN(C)C(=O)CCC(=O)NCCOCCOCCOCCO)Cc1cccc(c1)C(=O)Nc1sc2CC(C)(C)CCc2c1C(=O)c1cnn(c1)-c1ccc(Cl)c(c1)C(F)(F)F Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1016/j.bmcl.2022.128572 BindingDB Entry DOI: 10.7270/Q26977M6
					More data for this Ligand-Target Pair
Sodium/glucose cotransporter 2 (Homo sapiens (Human))	BDBM50503827 (CHEMBL4439652) Show SMILES Cc1cc(C)c(cc1Cc1ccc(\C=C\C(C)(C)C(=O)NC(C)(C)CO)cc1F)[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O |r| Show InChI InChI=1S/C31H42FNO7/c1-17-11-18(2)22(28-27(38)26(37)25(36)24(15-34)40-28)14-21(17)13-20-8-7-19(12-23(20)32)9-10-30(3,4)29(39)33-31(5,6)16-35/h7-12,14,24-28,34-38H,13,15-16H2,1-6H3,(H,33,39)/b10-9+/t24-,25-,26+,27-,28+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	17	n/a	n/a	n/a	n/a	n/a	n/a
Taisho Pharmaceutical Co., Ltd. Curated by ChEMBL					Assay Description Inhibition of human SGLT2 expressed in CHOK1 cells assessed as reduction in sodium-dependent glucose uptake after 1 hr in presence of [14C]-methyl-al...				Bioorg Med Chem 27: 394-409 (2019) Article DOI: 10.1016/j.bmc.2018.12.015 BindingDB Entry DOI: 10.7270/Q2X63R7F
					More data for this Ligand-Target Pair
Sodium/glucose cotransporter 2 (Homo sapiens (Human))	BDBM50503834 (CHEMBL4591009) Show SMILES COc1cc(C(C)C)c(Cc2ccc(\C=C\C(C)(C)C(=O)NC(C)(C)C(=O)N3CCNCC3)cc2)cc1[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O |r| Show InChI InChI=1S/C37H53N3O8/c1-22(2)26-20-28(47-7)27(33-32(44)31(43)30(42)29(21-41)48-33)19-25(26)18-24-10-8-23(9-11-24)12-13-36(3,4)34(45)39-37(5,6)35(46)40-16-14-38-15-17-40/h8-13,19-20,22,29-33,38,41-44H,14-18,21H2,1-7H3,(H,39,45)/b13-12+/t29-,30-,31+,32-,33+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	17	n/a	n/a	n/a	n/a	n/a	n/a
Taisho Pharmaceutical Co., Ltd. Curated by ChEMBL					Assay Description Inhibition of human SGLT2 expressed in CHOK1 cells assessed as reduction in sodium-dependent glucose uptake after 1 hr in presence of [14C]-methyl-al...				Bioorg Med Chem 27: 394-409 (2019) Article DOI: 10.1016/j.bmc.2018.12.015 BindingDB Entry DOI: 10.7270/Q2X63R7F
					More data for this Ligand-Target Pair
Egl nine homolog 1 (Homo sapiens (Human))	BDBM242563 (US9422240, 1-366) Show SMILES Cc1ccc(Oc2ccc(CN3CCC(O)=C(C(=O)NCC(O)=O)C3=O)cn2)cc1Cl |t:15| Show InChI InChI=1S/C21H20ClN3O6/c1-12-2-4-14(8-15(12)22)31-17-5-3-13(9-23-17)11-25-7-6-16(26)19(21(25)30)20(29)24-10-18(27)28/h2-5,8-9,26H,6-7,10-11H2,1H3,(H,24,29)(H,27,28)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	19	n/a	n/a	n/a	n/a	7.5	n/a
TAISHO PHARMACEUTICAL CO., LTD US Patent					Assay Description The enzyme and the substrate were each diluted with a 50 mM tris-hydrochloric acid buffer (pH 7.5) containing 12.5 mM KCl, 3.75 mM MgCl2, 25 μM ...				US Patent US9422240 (2016) BindingDB Entry DOI: 10.7270/Q24B307K
					More data for this Ligand-Target Pair
Egl nine homolog 1 (Homo sapiens (Human))	BDBM242526 (US9422240, 1-4) Show SMILES OC1=C(C(=O)NCC([O-])=O)C(=O)N(Cc2ccc(Oc3ccc(Cl)cc3)nc2)CC1 |c:1| Show InChI InChI=1S/C20H18ClN3O6/c21-13-2-4-14(5-3-13)30-16-6-1-12(9-22-16)11-24-8-7-15(25)18(20(24)29)19(28)23-10-17(26)27/h1-6,9,25H,7-8,10-11H2,(H,23,28)(H,26,27)/p-1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	US Patent	n/a	n/a	19	n/a	n/a	n/a	n/a	7.5	n/a
TAISHO PHARMACEUTICAL CO., LTD US Patent					Assay Description The enzyme and the substrate were each diluted with a 50 mM tris-hydrochloric acid buffer (pH 7.5) containing 12.5 mM KCl, 3.75 mM MgCl2, 25 μM ...				US Patent US9422240 (2016) BindingDB Entry DOI: 10.7270/Q24B307K
					More data for this Ligand-Target Pair
Sodium/glucose cotransporter 2 (Homo sapiens (Human))	BDBM50503822 (CHEMBL4460788) Show SMILES CC(C)c1cc(O)c(cc1Cc1ccc(\C=C\C(C)(C)C(=O)NC(C)(C)CO)cc1)[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O |r| Show InChI InChI=1S/C32H45NO8/c1-18(2)22-15-24(36)23(29-28(39)27(38)26(37)25(16-34)41-29)14-21(22)13-20-9-7-19(8-10-20)11-12-31(3,4)30(40)33-32(5,6)17-35/h7-12,14-15,18,25-29,34-39H,13,16-17H2,1-6H3,(H,33,40)/b12-11+/t25-,26-,27+,28-,29+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	19	n/a	n/a	n/a	n/a	n/a	n/a
Taisho Pharmaceutical Co., Ltd. Curated by ChEMBL					Assay Description Inhibition of human SGLT2 expressed in CHOK1 cells assessed as reduction in sodium-dependent glucose uptake after 1 hr in presence of [14C]-methyl-al...				Bioorg Med Chem 27: 394-409 (2019) Article DOI: 10.1016/j.bmc.2018.12.015 BindingDB Entry DOI: 10.7270/Q2X63R7F
					More data for this Ligand-Target Pair
Sodium/glucose cotransporter 2 (Homo sapiens (Human))	BDBM50503841 (CHEMBL4554040) Show SMILES COc1cc(C(C)C)c(Cc2ccc(\C=C\C(C)(C)C(=O)NC(C)(C)C(=O)NCCN(C)C)cc2)cc1[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O |r| Show InChI InChI=1S/C37H55N3O8/c1-22(2)26-20-28(47-9)27(33-32(44)31(43)30(42)29(21-41)48-33)19-25(26)18-24-12-10-23(11-13-24)14-15-36(3,4)34(45)39-37(5,6)35(46)38-16-17-40(7)8/h10-15,19-20,22,29-33,41-44H,16-18,21H2,1-9H3,(H,38,46)(H,39,45)/b15-14+/t29-,30-,31+,32-,33+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
Taisho Pharmaceutical Co., Ltd. Curated by ChEMBL					Assay Description Inhibition of human SGLT2 expressed in CHOK1 cells assessed as reduction in sodium-dependent glucose uptake after 1 hr in presence of [14C]-methyl-al...				Bioorg Med Chem 27: 394-409 (2019) Article DOI: 10.1016/j.bmc.2018.12.015 BindingDB Entry DOI: 10.7270/Q2X63R7F
					More data for this Ligand-Target Pair
Egl nine homolog 1 (Homo sapiens (Human))	BDBM242577 (US9422240, 1-443) Show SMILES OC(=O)CNC(=O)C1=C(O)CCN(Cc2cnc(Oc3ccc(cc3)C3CC3)cn2)C1=O |c:7| Show InChI InChI=1S/C22H22N4O6/c27-17-7-8-26(22(31)20(17)21(30)25-11-19(28)29)12-15-9-24-18(10-23-15)32-16-5-3-14(4-6-16)13-1-2-13/h3-6,9-10,13,27H,1-2,7-8,11-12H2,(H,25,30)(H,28,29)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	21	n/a	n/a	n/a	n/a	7.5	n/a
TAISHO PHARMACEUTICAL CO., LTD US Patent					Assay Description The enzyme and the substrate were each diluted with a 50 mM tris-hydrochloric acid buffer (pH 7.5) containing 12.5 mM KCl, 3.75 mM MgCl2, 25 μM ...				US Patent US9422240 (2016) BindingDB Entry DOI: 10.7270/Q24B307K
					More data for this Ligand-Target Pair
Sodium/glucose cotransporter 1 (Homo sapiens (Human))	BDBM50503835 (CHEMBL4524341) Show SMILES Cc1cc(O)c(cc1Cc1ccc(\C=C\C(C)(C)C(=O)NC(C)(C)CO)cc1)[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O |r| Show InChI InChI=1S/C30H41NO8/c1-17-12-22(34)21(27-26(37)25(36)24(35)23(15-32)39-27)14-20(17)13-19-8-6-18(7-9-19)10-11-29(2,3)28(38)31-30(4,5)16-33/h6-12,14,23-27,32-37H,13,15-16H2,1-5H3,(H,31,38)/b11-10+/t23-,24-,25+,26-,27+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	21	n/a	n/a	n/a	n/a	n/a	n/a
Taisho Pharmaceutical Co., Ltd. Curated by ChEMBL					Assay Description Inhibition of human SGLT1 expressed in CHOK1 cells assessed as reduction in sodium-dependent glucose uptake after 30 mins in presence of [14C]-methyl...				Bioorg Med Chem 27: 394-409 (2019) Article DOI: 10.1016/j.bmc.2018.12.015 BindingDB Entry DOI: 10.7270/Q2X63R7F
					More data for this Ligand-Target Pair
Sodium-dependent phosphate transport protein 2B (Homo sapiens (Human))	BDBM50600220 (CHEMBL5177872) Show SMILES CCN([C@H]1CC[C@@H](CC1)C(O)=O)S(=O)(=O)c1cccc(c1)C(=O)Nc1ccc(nc1C(=O)Nc1ccc(CCc2ccc(cc2)C(=O)NS(=O)(=O)NC)cc1)N1CCCCC1 |r,wU:6.9,wD:3.2,(2.67,-6.93,;1.33,-6.16,;1.33,-4.62,;2.67,-3.85,;4,-4.62,;5.33,-3.85,;5.33,-2.31,;4,-1.54,;2.67,-2.31,;6.67,-1.54,;8,-2.31,;6.67,-0,;-0,-3.85,;.77,-2.52,;-.77,-2.52,;-1.33,-4.62,;-1.33,-6.16,;-2.66,-6.93,;-4,-6.17,;-4,-4.62,;-2.66,-3.85,;-5.33,-3.85,;-6.66,-4.62,;-5.33,-2.31,;-6.66,-1.54,;-8,-2.31,;-9.33,-1.54,;-9.33,-.01,;-8,.77,;-6.66,-0,;-5.33,.77,;-5.33,2.31,;-4,-0,;-2.66,.77,;-2.66,2.31,;-1.33,3.08,;-0,2.31,;1.33,3.08,;2.67,2.31,;4,3.08,;4,4.63,;5.33,5.39,;6.66,4.62,;6.67,3.09,;5.34,2.31,;8,5.39,;8,6.93,;9.33,4.62,;10.67,5.39,;11.44,6.73,;9.9,6.73,;12,4.62,;13.33,5.39,;-0,.77,;-1.33,.01,;-10.67,.76,;-12,-.01,;-13.33,.76,;-13.33,2.3,;-12,3.07,;-10.67,2.3,)| Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	21	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1016/j.bmcl.2022.128700 BindingDB Entry DOI: 10.7270/Q28W3JB9
					More data for this Ligand-Target Pair
Egl nine homolog 1 (Homo sapiens (Human))	BDBM242566 (US9422240, 1-376) Show SMILES CCc1ccc(Oc2ccc(CN3CCC(O)=C(C(=O)NCC(O)=O)C3=O)cn2)cc1 |t:16| Show InChI InChI=1S/C22H23N3O6/c1-2-14-3-6-16(7-4-14)31-18-8-5-15(11-23-18)13-25-10-9-17(26)20(22(25)30)21(29)24-12-19(27)28/h3-8,11,26H,2,9-10,12-13H2,1H3,(H,24,29)(H,27,28)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	22	n/a	n/a	n/a	n/a	7.5	n/a
TAISHO PHARMACEUTICAL CO., LTD US Patent					Assay Description The enzyme and the substrate were each diluted with a 50 mM tris-hydrochloric acid buffer (pH 7.5) containing 12.5 mM KCl, 3.75 mM MgCl2, 25 μM ...				US Patent US9422240 (2016) BindingDB Entry DOI: 10.7270/Q24B307K
					More data for this Ligand-Target Pair
Sodium/glucose cotransporter 1 (Homo sapiens (Human))	BDBM50503838 (CHEMBL4450704) Show SMILES Cc1cc(C)c(cc1Cc1ccc(\C=C\C(C)(C)C(=O)NC(C)(C)CO)cc1)[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O |r| Show InChI InChI=1S/C31H43NO7/c1-18-13-19(2)23(28-27(37)26(36)25(35)24(16-33)39-28)15-22(18)14-21-9-7-20(8-10-21)11-12-30(3,4)29(38)32-31(5,6)17-34/h7-13,15,24-28,33-37H,14,16-17H2,1-6H3,(H,32,38)/b12-11+/t24-,25-,26+,27-,28+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	22	n/a	n/a	n/a	n/a	n/a	n/a
Taisho Pharmaceutical Co., Ltd. Curated by ChEMBL					Assay Description Inhibition of human SGLT1 expressed in CHOK1 cells assessed as reduction in sodium-dependent glucose uptake after 30 mins in presence of [14C]-methyl...				Bioorg Med Chem 27: 394-409 (2019) Article DOI: 10.1016/j.bmc.2018.12.015 BindingDB Entry DOI: 10.7270/Q2X63R7F
					More data for this Ligand-Target Pair
Sodium/glucose cotransporter 1 (Homo sapiens (Human))	BDBM50503822 (CHEMBL4460788) Show SMILES CC(C)c1cc(O)c(cc1Cc1ccc(\C=C\C(C)(C)C(=O)NC(C)(C)CO)cc1)[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O |r| Show InChI InChI=1S/C32H45NO8/c1-18(2)22-15-24(36)23(29-28(39)27(38)26(37)25(16-34)41-29)14-21(22)13-20-9-7-19(8-10-20)11-12-31(3,4)30(40)33-32(5,6)17-35/h7-12,14-15,18,25-29,34-39H,13,16-17H2,1-6H3,(H,33,40)/b12-11+/t25-,26-,27+,28-,29+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	23	n/a	n/a	n/a	n/a	n/a	n/a
Taisho Pharmaceutical Co., Ltd. Curated by ChEMBL					Assay Description Inhibition of human SGLT1 expressed in CHOK1 cells assessed as reduction in sodium-dependent glucose uptake after 30 mins in presence of [14C]-methyl...				Bioorg Med Chem 27: 394-409 (2019) Article DOI: 10.1016/j.bmc.2018.12.015 BindingDB Entry DOI: 10.7270/Q2X63R7F
					More data for this Ligand-Target Pair
Egl nine homolog 1 (Homo sapiens (Human))	BDBM242535 (US9422240, 1-254) Show SMILES OC(=O)CNC(=O)C1=C(O)CCN(Cc2ccc(Oc3ccc(cc3)C(F)(F)F)nc2)C1=O |c:7| Show InChI InChI=1S/C21H18F3N3O6/c22-21(23,24)13-2-4-14(5-3-13)33-16-6-1-12(9-25-16)11-27-8-7-15(28)18(20(27)32)19(31)26-10-17(29)30/h1-6,9,28H,7-8,10-11H2,(H,26,31)(H,29,30)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	24	n/a	n/a	n/a	n/a	7.5	n/a
TAISHO PHARMACEUTICAL CO., LTD US Patent					Assay Description The enzyme and the substrate were each diluted with a 50 mM tris-hydrochloric acid buffer (pH 7.5) containing 12.5 mM KCl, 3.75 mM MgCl2, 25 μM ...				US Patent US9422240 (2016) BindingDB Entry DOI: 10.7270/Q24B307K
					More data for this Ligand-Target Pair
Egl nine homolog 1 (Homo sapiens (Human))	BDBM242542 (US9422240, 1-265 | US9422240, 1-355) Show SMILES OC(=O)CNC(=O)C1=C(O)CCN(Cc2ccc(Oc3ccc(Cl)cc3)cc2)C1=O |c:7| Show InChI InChI=1S/C21H19ClN2O6/c22-14-3-7-16(8-4-14)30-15-5-1-13(2-6-15)12-24-10-9-17(25)19(21(24)29)20(28)23-11-18(26)27/h1-8,25H,9-12H2,(H,23,28)(H,26,27)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	24	n/a	n/a	n/a	n/a	7.5	n/a
TAISHO PHARMACEUTICAL CO., LTD US Patent					Assay Description The enzyme and the substrate were each diluted with a 50 mM tris-hydrochloric acid buffer (pH 7.5) containing 12.5 mM KCl, 3.75 mM MgCl2, 25 μM ...				US Patent US9422240 (2016) BindingDB Entry DOI: 10.7270/Q24B307K
					More data for this Ligand-Target Pair
Egl nine homolog 1 (Homo sapiens (Human))	BDBM242575 (US9422240, 1-409) Show SMILES Cc1cc(CN2CCC(O)=C(C(=O)NCC(O)=O)C2=O)cnc1Oc1ccc(Cl)cc1 |t:9| Show InChI InChI=1S/C21H20ClN3O6/c1-12-8-13(9-24-20(12)31-15-4-2-14(22)3-5-15)11-25-7-6-16(26)18(21(25)30)19(29)23-10-17(27)28/h2-5,8-9,26H,6-7,10-11H2,1H3,(H,23,29)(H,27,28)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	25	n/a	n/a	n/a	n/a	7.5	n/a
TAISHO PHARMACEUTICAL CO., LTD US Patent					Assay Description The enzyme and the substrate were each diluted with a 50 mM tris-hydrochloric acid buffer (pH 7.5) containing 12.5 mM KCl, 3.75 mM MgCl2, 25 μM ...				US Patent US9422240 (2016) BindingDB Entry DOI: 10.7270/Q24B307K
					More data for this Ligand-Target Pair
Egl nine homolog 1 (Homo sapiens (Human))	BDBM242564 (US9422240, 1-367) Show SMILES Cc1ccc(Oc2ccc(CN3CCC(O)=C(C(=O)NCC(O)=O)C3=O)cn2)cc1F |t:15| Show InChI InChI=1S/C21H20FN3O6/c1-12-2-4-14(8-15(12)22)31-17-5-3-13(9-23-17)11-25-7-6-16(26)19(21(25)30)20(29)24-10-18(27)28/h2-5,8-9,26H,6-7,10-11H2,1H3,(H,24,29)(H,27,28)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	26	n/a	n/a	n/a	n/a	7.5	n/a
TAISHO PHARMACEUTICAL CO., LTD US Patent					Assay Description The enzyme and the substrate were each diluted with a 50 mM tris-hydrochloric acid buffer (pH 7.5) containing 12.5 mM KCl, 3.75 mM MgCl2, 25 μM ...				US Patent US9422240 (2016) BindingDB Entry DOI: 10.7270/Q24B307K
					More data for this Ligand-Target Pair
Egl nine homolog 1 (Homo sapiens (Human))	BDBM242571 (US9422240, 1-392) Show SMILES Cc1ccc(Oc2ncc(CN3CCC(O)=C(C(=O)NCC(O)=O)C3=O)cc2Cl)cc1 |t:15| Show InChI InChI=1S/C21H20ClN3O6/c1-12-2-4-14(5-3-12)31-20-15(22)8-13(9-24-20)11-25-7-6-16(26)18(21(25)30)19(29)23-10-17(27)28/h2-5,8-9,26H,6-7,10-11H2,1H3,(H,23,29)(H,27,28)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	26	n/a	n/a	n/a	n/a	7.5	n/a
TAISHO PHARMACEUTICAL CO., LTD US Patent					Assay Description The enzyme and the substrate were each diluted with a 50 mM tris-hydrochloric acid buffer (pH 7.5) containing 12.5 mM KCl, 3.75 mM MgCl2, 25 μM ...				US Patent US9422240 (2016) BindingDB Entry DOI: 10.7270/Q24B307K
					More data for this Ligand-Target Pair
Sodium/glucose cotransporter 2 (Homo sapiens (Human))	BDBM50503832 (CHEMBL4514344) Show SMILES COc1cc(C(C)C)c(Cc2ccc(\C=C\C(C)(C)C(=O)NC(C)(C)C(=O)N3CCN(C)CC3)cc2)cc1[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O |r| Show InChI InChI=1S/C38H55N3O8/c1-23(2)27-21-29(48-8)28(34-33(45)32(44)31(43)30(22-42)49-34)20-26(27)19-25-11-9-24(10-12-25)13-14-37(3,4)35(46)39-38(5,6)36(47)41-17-15-40(7)16-18-41/h9-14,20-21,23,30-34,42-45H,15-19,22H2,1-8H3,(H,39,46)/b14-13+/t30-,31-,32+,33-,34+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	26	n/a	n/a	n/a	n/a	n/a	n/a
Taisho Pharmaceutical Co., Ltd. Curated by ChEMBL					Assay Description Inhibition of human SGLT2 expressed in CHOK1 cells assessed as reduction in sodium-dependent glucose uptake after 1 hr in presence of [14C]-methyl-al...				Bioorg Med Chem 27: 394-409 (2019) Article DOI: 10.1016/j.bmc.2018.12.015 BindingDB Entry DOI: 10.7270/Q2X63R7F
					More data for this Ligand-Target Pair
Sodium/glucose cotransporter 1 (Homo sapiens (Human))	BDBM50503837 (CHEMBL4516721) Show SMILES CC(C)c1cc(O)c(cc1Cc1ccc(\C=C\C(C)(C)C(=O)NC(C)(C)C(=O)NCC(C)(C)N)cc1C)[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O |r| Show InChI InChI=1S/C37H55N3O8/c1-20(2)25-17-27(42)26(32-31(45)30(44)29(43)28(18-41)48-32)16-24(25)15-23-11-10-22(14-21(23)3)12-13-35(4,5)33(46)40-37(8,9)34(47)39-19-36(6,7)38/h10-14,16-17,20,28-32,41-45H,15,18-19,38H2,1-9H3,(H,39,47)(H,40,46)/b13-12+/t28-,29-,30+,31-,32+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	27	n/a	n/a	n/a	n/a	n/a	n/a
Taisho Pharmaceutical Co., Ltd. Curated by ChEMBL					Assay Description Inhibition of human SGLT1 expressed in CHOK1 cells assessed as reduction in sodium-dependent glucose uptake after 30 mins in presence of [14C]-methyl...				Bioorg Med Chem 27: 394-409 (2019) Article DOI: 10.1016/j.bmc.2018.12.015 BindingDB Entry DOI: 10.7270/Q2X63R7F
					More data for this Ligand-Target Pair
Sodium/glucose cotransporter 2 (Homo sapiens (Human))	BDBM50503823 (CHEMBL4452698) Show SMILES CC(C)c1cc(O)c(cc1Cc1ccc(\C=C\C(C)(C)C(=O)NC(C)(C)C(=O)N2CCNCC2)cc1C)[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O |r| Show InChI InChI=1S/C37H53N3O8/c1-21(2)26-19-28(42)27(33-32(45)31(44)30(43)29(20-41)48-33)18-25(26)17-24-9-8-23(16-22(24)3)10-11-36(4,5)34(46)39-37(6,7)35(47)40-14-12-38-13-15-40/h8-11,16,18-19,21,29-33,38,41-45H,12-15,17,20H2,1-7H3,(H,39,46)/b11-10+/t29-,30-,31+,32-,33+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	28	n/a	n/a	n/a	n/a	n/a	n/a
Taisho Pharmaceutical Co., Ltd. Curated by ChEMBL					Assay Description Inhibition of human SGLT2 expressed in CHOK1 cells assessed as reduction in sodium-dependent glucose uptake after 1 hr in presence of [14C]-methyl-al...				Bioorg Med Chem 27: 394-409 (2019) Article DOI: 10.1016/j.bmc.2018.12.015 BindingDB Entry DOI: 10.7270/Q2X63R7F
					More data for this Ligand-Target Pair
Sodium-dependent phosphate transport protein 2B (Rattus norvegicus)	BDBM50594205 (CHEMBL5192917) Show SMILES CCC(CC)N(CCN(C)C(=O)CCC(O)=O)Cc1cccc(c1)C(=O)Nc1[nH]c2ccccc2c1C(=O)Nc1ccc(CCCc2ccc(cc2)C(O)=O)cc1 Show InChI	KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	28	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1016/j.bmc.2022.116783 BindingDB Entry DOI: 10.7270/Q2QF8XV1
					More data for this Ligand-Target Pair
Sodium/glucose cotransporter 1 (Homo sapiens (Human))	BDBM50503841 (CHEMBL4554040) Show SMILES COc1cc(C(C)C)c(Cc2ccc(\C=C\C(C)(C)C(=O)NC(C)(C)C(=O)NCCN(C)C)cc2)cc1[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O |r| Show InChI InChI=1S/C37H55N3O8/c1-22(2)26-20-28(47-9)27(33-32(44)31(43)30(42)29(21-41)48-33)19-25(26)18-24-12-10-23(11-13-24)14-15-36(3,4)34(45)39-37(5,6)35(46)38-16-17-40(7)8/h10-15,19-20,22,29-33,41-44H,16-18,21H2,1-9H3,(H,38,46)(H,39,45)/b15-14+/t29-,30-,31+,32-,33+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	29	n/a	n/a	n/a	n/a	n/a	n/a
Taisho Pharmaceutical Co., Ltd. Curated by ChEMBL					Assay Description Inhibition of human SGLT1 expressed in CHOK1 cells assessed as reduction in sodium-dependent glucose uptake after 30 mins in presence of [14C]-methyl...				Bioorg Med Chem 27: 394-409 (2019) Article DOI: 10.1016/j.bmc.2018.12.015 BindingDB Entry DOI: 10.7270/Q2X63R7F
					More data for this Ligand-Target Pair
Sodium/glucose cotransporter 1 (Homo sapiens (Human))	BDBM50503823 (CHEMBL4452698) Show SMILES CC(C)c1cc(O)c(cc1Cc1ccc(\C=C\C(C)(C)C(=O)NC(C)(C)C(=O)N2CCNCC2)cc1C)[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O |r| Show InChI InChI=1S/C37H53N3O8/c1-21(2)26-19-28(42)27(33-32(45)31(44)30(43)29(20-41)48-33)18-25(26)17-24-9-8-23(16-22(24)3)10-11-36(4,5)34(46)39-37(6,7)35(47)40-14-12-38-13-15-40/h8-11,16,18-19,21,29-33,38,41-45H,12-15,17,20H2,1-7H3,(H,39,46)/b11-10+/t29-,30-,31+,32-,33+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
Taisho Pharmaceutical Co., Ltd. Curated by ChEMBL					Assay Description Inhibition of human SGLT1 expressed in CHOK1 cells assessed as reduction in sodium-dependent glucose uptake after 30 mins in presence of [14C]-methyl...				Bioorg Med Chem 27: 394-409 (2019) Article DOI: 10.1016/j.bmc.2018.12.015 BindingDB Entry DOI: 10.7270/Q2X63R7F
					More data for this Ligand-Target Pair
Egl nine homolog 1 (Homo sapiens (Human))	BDBM242572 (US9422240, 1-393) Show SMILES Cc1ccc(Oc2ncc(CN3CCC(O)=C(C(=O)NCC(O)=O)C3=O)cc2F)cc1 |t:15| Show InChI InChI=1S/C21H20FN3O6/c1-12-2-4-14(5-3-12)31-20-15(22)8-13(9-24-20)11-25-7-6-16(26)18(21(25)30)19(29)23-10-17(27)28/h2-5,8-9,26H,6-7,10-11H2,1H3,(H,23,29)(H,27,28)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	32	n/a	n/a	n/a	n/a	7.5	n/a
TAISHO PHARMACEUTICAL CO., LTD US Patent					Assay Description The enzyme and the substrate were each diluted with a 50 mM tris-hydrochloric acid buffer (pH 7.5) containing 12.5 mM KCl, 3.75 mM MgCl2, 25 μM ...				US Patent US9422240 (2016) BindingDB Entry DOI: 10.7270/Q24B307K
					More data for this Ligand-Target Pair
Sodium/glucose cotransporter 1 (Homo sapiens (Human))	BDBM50503825 (CHEMBL4564494) Show SMILES COc1cc(C(C)C)c(Cc2ccc(\C=C\C(C)(C)C(=O)NC(C)(C)C(=O)NCCN3CCNCC3)cc2C)cc1[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O |r| Show InChI InChI=1S/C40H60N4O8/c1-24(2)29-22-31(51-8)30(36-35(48)34(47)33(46)32(23-45)52-36)21-28(29)20-27-10-9-26(19-25(27)3)11-12-39(4,5)37(49)43-40(6,7)38(50)42-15-18-44-16-13-41-14-17-44/h9-12,19,21-22,24,32-36,41,45-48H,13-18,20,23H2,1-8H3,(H,42,50)(H,43,49)/b12-11+/t32-,33-,34+,35-,36+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	34	n/a	n/a	n/a	n/a	n/a	n/a
Taisho Pharmaceutical Co., Ltd. Curated by ChEMBL					Assay Description Inhibition of human SGLT1 expressed in CHOK1 cells assessed as reduction in sodium-dependent glucose uptake after 30 mins in presence of [14C]-methyl...				Bioorg Med Chem 27: 394-409 (2019) Article DOI: 10.1016/j.bmc.2018.12.015 BindingDB Entry DOI: 10.7270/Q2X63R7F
					More data for this Ligand-Target Pair
Sodium/glucose cotransporter 1 (Homo sapiens (Human))	BDBM50503827 (CHEMBL4439652) Show SMILES Cc1cc(C)c(cc1Cc1ccc(\C=C\C(C)(C)C(=O)NC(C)(C)CO)cc1F)[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O |r| Show InChI InChI=1S/C31H42FNO7/c1-17-11-18(2)22(28-27(38)26(37)25(36)24(15-34)40-28)14-21(17)13-20-8-7-19(12-23(20)32)9-10-30(3,4)29(39)33-31(5,6)16-35/h7-12,14,24-28,34-38H,13,15-16H2,1-6H3,(H,33,39)/b10-9+/t24-,25-,26+,27-,28+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	34	n/a	n/a	n/a	n/a	n/a	n/a
Taisho Pharmaceutical Co., Ltd. Curated by ChEMBL					Assay Description Inhibition of human SGLT1 expressed in CHOK1 cells assessed as reduction in sodium-dependent glucose uptake after 30 mins in presence of [14C]-methyl...				Bioorg Med Chem 27: 394-409 (2019) Article DOI: 10.1016/j.bmc.2018.12.015 BindingDB Entry DOI: 10.7270/Q2X63R7F
					More data for this Ligand-Target Pair
Sodium/glucose cotransporter 2 (Homo sapiens (Human))	BDBM50503840 (CHEMBL4551742) Show SMILES COc1cc(C(C)C)c(Cc2ccc(\C=C\C(C)(C)C(=O)NC(C)(C)CO)cc2)cc1[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O |r| Show InChI InChI=1S/C33H47NO8/c1-19(2)23-16-25(41-7)24(30-29(39)28(38)27(37)26(17-35)42-30)15-22(23)14-21-10-8-20(9-11-21)12-13-32(3,4)31(40)34-33(5,6)18-36/h8-13,15-16,19,26-30,35-39H,14,17-18H2,1-7H3,(H,34,40)/b13-12+/t26-,27-,28+,29-,30+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	34	n/a	n/a	n/a	n/a	n/a	n/a
Taisho Pharmaceutical Co., Ltd. Curated by ChEMBL					Assay Description Inhibition of human SGLT2 expressed in CHOK1 cells assessed as reduction in sodium-dependent glucose uptake after 1 hr in presence of [14C]-methyl-al...				Bioorg Med Chem 27: 394-409 (2019) Article DOI: 10.1016/j.bmc.2018.12.015 BindingDB Entry DOI: 10.7270/Q2X63R7F
					More data for this Ligand-Target Pair
Sodium/glucose cotransporter 1 (Homo sapiens (Human))	BDBM50503824 (CHEMBL4457957) Show SMILES CC(C)c1cc(O)c(cc1Cc1ccc(\C=C\C(C)(C)C(=O)NC(C)(C)C(=O)N2CCN(C)CC2)cc1C)[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O |r| Show InChI InChI=1S/C38H55N3O8/c1-22(2)27-20-29(43)28(34-33(46)32(45)31(44)30(21-42)49-34)19-26(27)18-25-10-9-24(17-23(25)3)11-12-37(4,5)35(47)39-38(6,7)36(48)41-15-13-40(8)14-16-41/h9-12,17,19-20,22,30-34,42-46H,13-16,18,21H2,1-8H3,(H,39,47)/b12-11+/t30-,31-,32+,33-,34+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	35	n/a	n/a	n/a	n/a	n/a	n/a
Taisho Pharmaceutical Co., Ltd. Curated by ChEMBL					Assay Description Inhibition of human SGLT1 expressed in CHOK1 cells assessed as reduction in sodium-dependent glucose uptake after 30 mins in presence of [14C]-methyl...				Bioorg Med Chem 27: 394-409 (2019) Article DOI: 10.1016/j.bmc.2018.12.015 BindingDB Entry DOI: 10.7270/Q2X63R7F
					More data for this Ligand-Target Pair
Sodium/glucose cotransporter 1 (Homo sapiens (Human))	BDBM50503833 (CHEMBL4472308) Show SMILES CC(C)c1cc(O)c(cc1Cc1ccc(\C=C\C(C)(C)C(=O)NC(C)(C)C(=O)NCCN(C)C)cc1C)[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O |r| Show InChI InChI=1S/C37H55N3O8/c1-21(2)26-19-28(42)27(33-32(45)31(44)30(43)29(20-41)48-33)18-25(26)17-24-11-10-23(16-22(24)3)12-13-36(4,5)34(46)39-37(6,7)35(47)38-14-15-40(8)9/h10-13,16,18-19,21,29-33,41-45H,14-15,17,20H2,1-9H3,(H,38,47)(H,39,46)/b13-12+/t29-,30-,31+,32-,33+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	35	n/a	n/a	n/a	n/a	n/a	n/a
Taisho Pharmaceutical Co., Ltd. Curated by ChEMBL					Assay Description Inhibition of human SGLT1 expressed in CHOK1 cells assessed as reduction in sodium-dependent glucose uptake after 30 mins in presence of [14C]-methyl...				Bioorg Med Chem 27: 394-409 (2019) Article DOI: 10.1016/j.bmc.2018.12.015 BindingDB Entry DOI: 10.7270/Q2X63R7F
					More data for this Ligand-Target Pair
Sodium/glucose cotransporter 1 (Homo sapiens (Human))	BDBM50503840 (CHEMBL4551742) Show SMILES COc1cc(C(C)C)c(Cc2ccc(\C=C\C(C)(C)C(=O)NC(C)(C)CO)cc2)cc1[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O |r| Show InChI InChI=1S/C33H47NO8/c1-19(2)23-16-25(41-7)24(30-29(39)28(38)27(37)26(17-35)42-30)15-22(23)14-21-10-8-20(9-11-21)12-13-32(3,4)31(40)34-33(5,6)18-36/h8-13,15-16,19,26-30,35-39H,14,17-18H2,1-7H3,(H,34,40)/b13-12+/t26-,27-,28+,29-,30+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	36	n/a	n/a	n/a	n/a	n/a	n/a
Taisho Pharmaceutical Co., Ltd. Curated by ChEMBL					Assay Description Inhibition of human SGLT1 expressed in CHOK1 cells assessed as reduction in sodium-dependent glucose uptake after 30 mins in presence of [14C]-methyl...				Bioorg Med Chem 27: 394-409 (2019) Article DOI: 10.1016/j.bmc.2018.12.015 BindingDB Entry DOI: 10.7270/Q2X63R7F
					More data for this Ligand-Target Pair
Sodium-dependent phosphate transport protein 2B (Homo sapiens (Human))	BDBM50600212 (CHEMBL5177122) Show SMILES CCC(CC)N(CCN(C)C(=O)CCC(O)=O)Cc1cccc(c1)C(=O)Nc1ccc(nc1C(=O)Nc1ccc(CCc2ccc(cc2)C(O)=O)cc1)N1CCCCC1 Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	36	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1016/j.bmcl.2022.128700 BindingDB Entry DOI: 10.7270/Q28W3JB9
					More data for this Ligand-Target Pair
Sodium-dependent phosphate transport protein 2B (Homo sapiens (Human))	BDBM50596515 (CHEMBL5204879) Show SMILES CCC(CC)N(CCN(C)C(=O)CCC(O)=O)Cc1cccc(c1)C(=O)Nc1sc2CC(C)(C)CCc2c1C(=O)c1cnn(c1)-c1ccc(Cl)cc1 Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	36	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1016/j.bmcl.2022.128572 BindingDB Entry DOI: 10.7270/Q26977M6
					More data for this Ligand-Target Pair
Sodium/glucose cotransporter 1 (Homo sapiens (Human))	BDBM50503834 (CHEMBL4591009) Show SMILES COc1cc(C(C)C)c(Cc2ccc(\C=C\C(C)(C)C(=O)NC(C)(C)C(=O)N3CCNCC3)cc2)cc1[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O |r| Show InChI InChI=1S/C37H53N3O8/c1-22(2)26-20-28(47-7)27(33-32(44)31(43)30(42)29(21-41)48-33)19-25(26)18-24-10-8-23(9-11-24)12-13-36(3,4)34(45)39-37(5,6)35(46)40-16-14-38-15-17-40/h8-13,19-20,22,29-33,38,41-44H,14-18,21H2,1-7H3,(H,39,45)/b13-12+/t29-,30-,31+,32-,33+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	38	n/a	n/a	n/a	n/a	n/a	n/a
Taisho Pharmaceutical Co., Ltd. Curated by ChEMBL					Assay Description Inhibition of human SGLT1 expressed in CHOK1 cells assessed as reduction in sodium-dependent glucose uptake after 30 mins in presence of [14C]-methyl...				Bioorg Med Chem 27: 394-409 (2019) Article DOI: 10.1016/j.bmc.2018.12.015 BindingDB Entry DOI: 10.7270/Q2X63R7F
					More data for this Ligand-Target Pair
Sodium-dependent phosphate transport protein 2B (Homo sapiens (Human))	BDBM50596516 (CHEMBL5192822) Show SMILES CCC(CC)N(CCN(C)C(=O)CCC(O)=O)Cc1cccc(c1)C(=O)Nc1sc2CC(C)(C)CCc2c1C(=O)c1cnn(c1)-c1ccc(Cl)c(c1)C(F)(F)F Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	38	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1016/j.bmcl.2022.128572 BindingDB Entry DOI: 10.7270/Q26977M6
					More data for this Ligand-Target Pair
Egl nine homolog 1 (Homo sapiens (Human))	BDBM242576 (US9422240, 1-440) Show SMILES OC(=O)CNC(=O)C1=C(O)CCN(Cc2cnc(Oc3ccc(Cl)cc3)cn2)C1=O |c:7| Show InChI InChI=1S/C19H17ClN4O6/c20-11-1-3-13(4-2-11)30-15-8-21-12(7-22-15)10-24-6-5-14(25)17(19(24)29)18(28)23-9-16(26)27/h1-4,7-8,25H,5-6,9-10H2,(H,23,28)(H,26,27)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	39	n/a	n/a	n/a	n/a	7.5	n/a
TAISHO PHARMACEUTICAL CO., LTD US Patent					Assay Description The enzyme and the substrate were each diluted with a 50 mM tris-hydrochloric acid buffer (pH 7.5) containing 12.5 mM KCl, 3.75 mM MgCl2, 25 μM ...				US Patent US9422240 (2016) BindingDB Entry DOI: 10.7270/Q24B307K
					More data for this Ligand-Target Pair
Egl nine homolog 1 (Homo sapiens (Human))	BDBM242528 (US9422240, 1-70) Show SMILES Cc1ccc(Oc2ccc(CN3CCC(O)=C(C(=O)NCC(O)=O)C3=O)cn2)cc1 |t:15| Show InChI InChI=1S/C21H21N3O6/c1-13-2-5-15(6-3-13)30-17-7-4-14(10-22-17)12-24-9-8-16(25)19(21(24)29)20(28)23-11-18(26)27/h2-7,10,25H,8-9,11-12H2,1H3,(H,23,28)(H,26,27)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	39	n/a	n/a	n/a	n/a	7.5	n/a
TAISHO PHARMACEUTICAL CO., LTD US Patent					Assay Description The enzyme and the substrate were each diluted with a 50 mM tris-hydrochloric acid buffer (pH 7.5) containing 12.5 mM KCl, 3.75 mM MgCl2, 25 μM ...				US Patent US9422240 (2016) BindingDB Entry DOI: 10.7270/Q24B307K
					More data for this Ligand-Target Pair
Sodium-dependent phosphate transport protein 2B (Homo sapiens (Human))	BDBM50596525 (CHEMBL5177313) Show SMILES CCC(CC)N(CCN(C)C(=O)CCC(O)=O)S(=O)(=O)c1cccc(c1)C(=O)Nc1sc2CC(C)(C)CCc2c1C(=O)c1cnn(c1)-c1ccc(Cl)c(c1)C(F)(F)F Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	39	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1016/j.bmcl.2022.128572 BindingDB Entry DOI: 10.7270/Q26977M6
					More data for this Ligand-Target Pair
Egl nine homolog 1 (Homo sapiens (Human))	BDBM242532 (US9422240, 1-225) Show SMILES OC(=O)CNC(=O)C1=C(O)CCN(Cc2ccc(Oc3ccc(cc3)C#N)nc2)C1=O |c:7| Show InChI InChI=1S/C21H18N4O6/c22-9-13-1-4-15(5-2-13)31-17-6-3-14(10-23-17)12-25-8-7-16(26)19(21(25)30)20(29)24-11-18(27)28/h1-6,10,26H,7-8,11-12H2,(H,24,29)(H,27,28)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	40	n/a	n/a	n/a	n/a	7.5	n/a
TAISHO PHARMACEUTICAL CO., LTD US Patent					Assay Description The enzyme and the substrate were each diluted with a 50 mM tris-hydrochloric acid buffer (pH 7.5) containing 12.5 mM KCl, 3.75 mM MgCl2, 25 μM ...				US Patent US9422240 (2016) BindingDB Entry DOI: 10.7270/Q24B307K
					More data for this Ligand-Target Pair
Egl nine homolog 1 (Homo sapiens (Human))	BDBM242548 (US9422240, 1-284) Show SMILES OC(=O)CNC(=O)C1=C(O)CCN(Cc2ccc(Oc3cccc(Cl)c3)nc2)C1=O |c:7| Show InChI InChI=1S/C20H18ClN3O6/c21-13-2-1-3-14(8-13)30-16-5-4-12(9-22-16)11-24-7-6-15(25)18(20(24)29)19(28)23-10-17(26)27/h1-5,8-9,25H,6-7,10-11H2,(H,23,28)(H,26,27)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	40	n/a	n/a	n/a	n/a	7.5	n/a
TAISHO PHARMACEUTICAL CO., LTD US Patent					Assay Description The enzyme and the substrate were each diluted with a 50 mM tris-hydrochloric acid buffer (pH 7.5) containing 12.5 mM KCl, 3.75 mM MgCl2, 25 μM ...				US Patent US9422240 (2016) BindingDB Entry DOI: 10.7270/Q24B307K
					More data for this Ligand-Target Pair
Egl nine homolog 1 (Homo sapiens (Human))	BDBM242565 (US9422240, 1-368) Show SMILES Cc1cc(Oc2ccc(CN3CCC(O)=C(C(=O)NCC(O)=O)C3=O)cn2)ccc1F |t:14| Show InChI InChI=1S/C21H20FN3O6/c1-12-8-14(3-4-15(12)22)31-17-5-2-13(9-23-17)11-25-7-6-16(26)19(21(25)30)20(29)24-10-18(27)28/h2-5,8-9,26H,6-7,10-11H2,1H3,(H,24,29)(H,27,28)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	41	n/a	n/a	n/a	n/a	7.5	n/a
TAISHO PHARMACEUTICAL CO., LTD US Patent					Assay Description The enzyme and the substrate were each diluted with a 50 mM tris-hydrochloric acid buffer (pH 7.5) containing 12.5 mM KCl, 3.75 mM MgCl2, 25 μM ...				US Patent US9422240 (2016) BindingDB Entry DOI: 10.7270/Q24B307K
					More data for this Ligand-Target Pair
Sodium/glucose cotransporter 1 (Homo sapiens (Human))	BDBM50503832 (CHEMBL4514344) Show SMILES COc1cc(C(C)C)c(Cc2ccc(\C=C\C(C)(C)C(=O)NC(C)(C)C(=O)N3CCN(C)CC3)cc2)cc1[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O |r| Show InChI InChI=1S/C38H55N3O8/c1-23(2)27-21-29(48-8)28(34-33(45)32(44)31(43)30(22-42)49-34)20-26(27)19-25-11-9-24(10-12-25)13-14-37(3,4)35(46)39-38(5,6)36(47)41-17-15-40(7)16-18-41/h9-14,20-21,23,30-34,42-45H,15-19,22H2,1-8H3,(H,39,46)/b14-13+/t30-,31-,32+,33-,34+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	42	n/a	n/a	n/a	n/a	n/a	n/a
Taisho Pharmaceutical Co., Ltd. Curated by ChEMBL					Assay Description Inhibition of human SGLT1 expressed in CHOK1 cells assessed as reduction in sodium-dependent glucose uptake after 30 mins in presence of [14C]-methyl...				Bioorg Med Chem 27: 394-409 (2019) Article DOI: 10.1016/j.bmc.2018.12.015 BindingDB Entry DOI: 10.7270/Q2X63R7F
					More data for this Ligand-Target Pair
Sodium-dependent phosphate transport protein 2B (Homo sapiens (Human))	BDBM50596524 (CHEMBL5188308) Show SMILES CCN([C@H]1CC[C@@H](CC1)C(O)=O)S(=O)(=O)c1cccc(c1)C(=O)Nc1sc2CC(C)(C)CCc2c1C(=O)c1cnn(c1)-c1ccc(Cl)c(c1)C(F)(F)F |r,wU:3.2,wD:6.9,(2.37,-6.5,;3.71,-5.73,;3.71,-4.19,;5.04,-3.42,;5.04,-1.88,;6.37,-1.11,;7.71,-1.88,;7.71,-3.42,;6.37,-4.19,;9.04,-1.11,;10.37,-1.88,;9.04,.43,;2.37,-3.42,;3.14,-2.08,;1.6,-2.08,;1.04,-4.19,;1.04,-5.73,;-.29,-6.5,;-1.62,-5.74,;-1.62,-4.19,;-.29,-3.42,;-2.96,-3.42,;-4.29,-4.19,;-2.96,-1.88,;-4.29,-1.11,;-5.7,-1.74,;-6.73,-.59,;-8.27,-.59,;-9.04,.74,;-10.37,1.51,;-10.37,-.03,;-8.27,2.07,;-6.73,2.07,;-5.96,.74,;-4.45,.42,;-3.36,1.51,;-3.76,3,;-1.88,1.11,;-1.32,-.33,;.21,-.24,;.61,1.24,;-.68,2.08,;2.1,1.64,;3.19,.55,;4.68,.95,;5.07,2.43,;6.56,2.83,;3.98,3.52,;2.5,3.13,;4.38,5.01,;3.29,6.1,;5.87,5.41,;4.78,6.5,)| Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	42	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1016/j.bmcl.2022.128572 BindingDB Entry DOI: 10.7270/Q26977M6
					More data for this Ligand-Target Pair

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