Compile Data Set for Download or QSAR
Found 479 of ic50 data for polymerid = 8772
TargetTyrosine-protein kinase TXK(Homo sapiens (Human))
GB005, Inc.

US Patent
LigandPNGBDBM458182(US10752615, Compound 75)copy SMILEScopy InChI
Affinity DataIC50: 0.120nMAssay Description:The in vitro kinase assays were performed at Nanosyn (Santa Clara, Calif.) utilizing microfluidic detection technology. The test compounds were seria...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2G163WGUS Patent
TargetTyrosine-protein kinase TXK(Homo sapiens (Human))
GB005, Inc.

US Patent
LigandPNGBDBM50458604(CHEMBL4214683 | US10752615, Compound 149)copy SMILEScopy InChI
Affinity DataIC50: 0.140nMAssay Description:The in vitro kinase assays were performed at Nanosyn (Santa Clara, Calif.) utilizing microfluidic detection technology. The test compounds were seria...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2G163WGUS Patent
TargetTyrosine-protein kinase TXK(Homo sapiens (Human))
GB005, Inc.

US Patent
LigandPNGBDBM50458604(CHEMBL4214683 | US10752615, Compound 149)copy SMILEScopy InChI
Affinity DataIC50: 0.140nMAssay Description:Inhibition of TXK (unknown origin) using fluorescently labeled peptide as substrate after 3 hrs by microfluidic mobility shift assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22V2JQNPubMed
TargetTyrosine-protein kinase TXK(Homo sapiens (Human))
GB005, Inc.

US Patent
LigandPNGBDBM50458600(CHEMBL4206765 | US10752615, Compound 97)copy SMILEScopy InChI
Affinity DataIC50: 0.140nMAssay Description:Inhibition of TXK (unknown origin) using fluorescently labeled peptide as substrate after 3 hrs by microfluidic mobility shift assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22V2JQNPubMed
TargetTyrosine-protein kinase TXK(Homo sapiens (Human))
GB005, Inc.

US Patent
LigandPNGBDBM50458600(CHEMBL4206765 | US10752615, Compound 97)copy SMILEScopy InChI
Affinity DataIC50: 0.140nMAssay Description:The in vitro kinase assays were performed at Nanosyn (Santa Clara, Calif.) utilizing microfluidic detection technology. The test compounds were seria...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2G163WGUS Patent
TargetTyrosine-protein kinase TXK(Homo sapiens (Human))
GB005, Inc.

US Patent
LigandPNGBDBM50458601(CHEMBL4217959 | US10752615, Compound 138)copy SMILEScopy InChI
Affinity DataIC50: 0.160nMAssay Description:Inhibition of TXK (unknown origin) using fluorescently labeled peptide as substrate after 3 hrs by microfluidic mobility shift assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22V2JQNPubMed
TargetTyrosine-protein kinase TXK(Homo sapiens (Human))
GB005, Inc.

US Patent
LigandPNGBDBM458238(US10752615, Compound 136)copy SMILES
Affinity DataIC50: 0.160nMAssay Description:The in vitro kinase assays were performed at Nanosyn (Santa Clara, Calif.) utilizing microfluidic detection technology. The test compounds were seria...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2G163WGUS Patent
TargetTyrosine-protein kinase TXK(Homo sapiens (Human))
GB005, Inc.

US Patent
LigandPNGBDBM50458601(CHEMBL4217959 | US10752615, Compound 138)copy SMILEScopy InChI
Affinity DataIC50: 0.160nMAssay Description:The in vitro kinase assays were performed at Nanosyn (Santa Clara, Calif.) utilizing microfluidic detection technology. The test compounds were seria...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2G163WGUS Patent
TargetTyrosine-protein kinase TXK(Homo sapiens (Human))
GB005, Inc.

US Patent
LigandPNGBDBM50458597(CHEMBL4203077 | US10752615, Compound 4)copy SMILEScopy InChI
Affinity DataIC50: 0.180nMAssay Description:Inhibition of TXK (unknown origin) using fluorescently labeled peptide as substrate after 3 hrs by microfluidic mobility shift assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22V2JQNPubMed
TargetTyrosine-protein kinase TXK(Homo sapiens (Human))
GB005, Inc.

US Patent
LigandPNGBDBM50458588(CHEMBL4219011 | US10752615, Compound 131)copy SMILEScopy InChI
Affinity DataIC50: 0.180nMAssay Description:Inhibition of TXK (unknown origin) using fluorescently labeled peptide as substrate after 3 hrs by microfluidic mobility shift assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22V2JQNPubMed
TargetTyrosine-protein kinase TXK(Homo sapiens (Human))
GB005, Inc.

US Patent
LigandPNGBDBM50458588(CHEMBL4219011 | US10752615, Compound 131)copy SMILEScopy InChI
Affinity DataIC50: 0.180nMAssay Description:The in vitro kinase assays were performed at Nanosyn (Santa Clara, Calif.) utilizing microfluidic detection technology. The test compounds were seria...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2G163WGUS Patent
TargetTyrosine-protein kinase TXK(Homo sapiens (Human))
GB005, Inc.

US Patent
LigandPNGBDBM50458597(CHEMBL4203077 | US10752615, Compound 4)copy SMILEScopy InChI
Affinity DataIC50: 0.180nMAssay Description:The in vitro kinase assays were performed at Nanosyn (Santa Clara, Calif.) utilizing microfluidic detection technology. The test compounds were seria...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2G163WGUS Patent
TargetTyrosine-protein kinase TXK(Homo sapiens (Human))
GB005, Inc.

US Patent
LigandPNGBDBM458213(US10752615, Compound 110)copy SMILEScopy InChI
Affinity DataIC50: 0.180nMAssay Description:The in vitro kinase assays were performed at Nanosyn (Santa Clara, Calif.) utilizing microfluidic detection technology. The test compounds were seria...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2G163WGUS Patent
TargetTyrosine-protein kinase TXK(Homo sapiens (Human))
GB005, Inc.

US Patent
LigandPNGBDBM458247(US10752615, Compound 145)copy SMILEScopy InChI
Affinity DataIC50: 0.200nMAssay Description:The in vitro kinase assays were performed at Nanosyn (Santa Clara, Calif.) utilizing microfluidic detection technology. The test compounds were seria...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2G163WGUS Patent
TargetTyrosine-protein kinase TXK(Homo sapiens (Human))
GB005, Inc.

US Patent
LigandPNGBDBM458242(US10752615, Compound 140)copy SMILEScopy InChI
Affinity DataIC50: 0.200nMAssay Description:The in vitro kinase assays were performed at Nanosyn (Santa Clara, Calif.) utilizing microfluidic detection technology. The test compounds were seria...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2G163WGUS Patent
TargetTyrosine-protein kinase TXK(Homo sapiens (Human))
GB005, Inc.

US Patent
LigandPNGBDBM458230(US10752615, Compound 128)copy SMILEScopy InChI
Affinity DataIC50: 0.200nMAssay Description:The in vitro kinase assays were performed at Nanosyn (Santa Clara, Calif.) utilizing microfluidic detection technology. The test compounds were seria...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2G163WGUS Patent
TargetTyrosine-protein kinase TXK(Homo sapiens (Human))
GB005, Inc.

US Patent
LigandPNGBDBM50458587(CHEMBL4207292)copy SMILEScopy InChI
Affinity DataIC50: 0.200nMAssay Description:Inhibition of TXK (unknown origin) using fluorescently labeled peptide as substrate after 3 hrs by microfluidic mobility shift assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22V2JQNPubMed
TargetTyrosine-protein kinase TXK(Homo sapiens (Human))
GB005, Inc.

US Patent
LigandPNGBDBM458119(US10752615, Compound 9)copy SMILEScopy InChI
Affinity DataIC50: 0.200nMAssay Description:The in vitro kinase assays were performed at Nanosyn (Santa Clara, Calif.) utilizing microfluidic detection technology. The test compounds were seria...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2G163WGUS Patent
TargetTyrosine-protein kinase TXK(Homo sapiens (Human))
GB005, Inc.

US Patent
LigandPNGBDBM384539(N-(1-(((R)-1-acryloylpyrrolidin-2-yl)methyl)-5-(((...)copy SMILEScopy InChI
Affinity DataIC50: 0.200nMAssay Description:The ability of the compounds of the present disclosure to inhibit ITK was measured using the Caliper assay format, which is an electrophoretic separa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q21Z46RFUS Patent
TargetTyrosine-protein kinase TXK(Homo sapiens (Human))
GB005, Inc.

US Patent
LigandPNGBDBM458231(US10752615, Compound 129)copy SMILES
Affinity DataIC50: 0.210nMAssay Description:The in vitro kinase assays were performed at Nanosyn (Santa Clara, Calif.) utilizing microfluidic detection technology. The test compounds were seria...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2G163WGUS Patent
TargetTyrosine-protein kinase TXK(Homo sapiens (Human))
GB005, Inc.

US Patent
LigandPNGBDBM458249(US10752615, Compound 147)copy SMILEScopy InChI
Affinity DataIC50: 0.210nMAssay Description:The in vitro kinase assays were performed at Nanosyn (Santa Clara, Calif.) utilizing microfluidic detection technology. The test compounds were seria...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2G163WGUS Patent
TargetTyrosine-protein kinase TXK(Homo sapiens (Human))
GB005, Inc.

US Patent
LigandPNGBDBM50458592(CHEMBL4211372 | US10752615, Compound 16)copy SMILEScopy InChI
Affinity DataIC50: 0.210nMAssay Description:The in vitro kinase assays were performed at Nanosyn (Santa Clara, Calif.) utilizing microfluidic detection technology. The test compounds were seria...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2G163WGUS Patent
TargetTyrosine-protein kinase TXK(Homo sapiens (Human))
GB005, Inc.

US Patent
LigandPNGBDBM50458592(CHEMBL4211372 | US10752615, Compound 16)copy SMILEScopy InChI
Affinity DataIC50: 0.210nMAssay Description:Inhibition of TXK (unknown origin) using fluorescently labeled peptide as substrate after 3 hrs by microfluidic mobility shift assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22V2JQNPubMed
TargetTyrosine-protein kinase TXK(Homo sapiens (Human))
GB005, Inc.

US Patent
LigandPNGBDBM458216(US10752615, Compound 114)copy SMILEScopy InChI
Affinity DataIC50: 0.220nMAssay Description:The in vitro kinase assays were performed at Nanosyn (Santa Clara, Calif.) utilizing microfluidic detection technology. The test compounds were seria...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2G163WGUS Patent
TargetTyrosine-protein kinase TXK(Homo sapiens (Human))
GB005, Inc.

US Patent
LigandPNGBDBM458248(US10752615, Compound 146)copy SMILEScopy InChI
Affinity DataIC50: 0.220nMAssay Description:The in vitro kinase assays were performed at Nanosyn (Santa Clara, Calif.) utilizing microfluidic detection technology. The test compounds were seria...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2G163WGUS Patent
TargetTyrosine-protein kinase TXK(Homo sapiens (Human))
GB005, Inc.

US Patent
LigandPNGBDBM50458589(CHEMBL4208358 | US10752615, Compound 57)copy SMILEScopy InChI
Affinity DataIC50: 0.220nMAssay Description:The in vitro kinase assays were performed at Nanosyn (Santa Clara, Calif.) utilizing microfluidic detection technology. The test compounds were seria...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2G163WGUS Patent
TargetTyrosine-protein kinase TXK(Homo sapiens (Human))
GB005, Inc.

US Patent
LigandPNGBDBM50458589(CHEMBL4208358 | US10752615, Compound 57)copy SMILEScopy InChI
Affinity DataIC50: 0.220nMAssay Description:Inhibition of TXK (unknown origin) using fluorescently labeled peptide as substrate after 3 hrs by microfluidic mobility shift assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22V2JQNPubMed
TargetTyrosine-protein kinase TXK(Homo sapiens (Human))
GB005, Inc.

US Patent
LigandPNGBDBM458227(US10752615, Compound 125)copy SMILEScopy InChI
Affinity DataIC50: 0.240nMAssay Description:The in vitro kinase assays were performed at Nanosyn (Santa Clara, Calif.) utilizing microfluidic detection technology. The test compounds were seria...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2G163WGUS Patent
TargetTyrosine-protein kinase TXK(Homo sapiens (Human))
GB005, Inc.

US Patent
LigandPNGBDBM458258(US10752615, Compound 156)copy SMILES
Affinity DataIC50: 0.240nMAssay Description:The in vitro kinase assays were performed at Nanosyn (Santa Clara, Calif.) utilizing microfluidic detection technology. The test compounds were seria...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2G163WGUS Patent
TargetTyrosine-protein kinase TXK(Homo sapiens (Human))
GB005, Inc.

US Patent
LigandPNGBDBM50458596(CHEMBL4216187 | US10752615, Compound 50)copy SMILEScopy InChI
Affinity DataIC50: 0.25nMAssay Description:The in vitro kinase assays were performed at Nanosyn (Santa Clara, Calif.) utilizing microfluidic detection technology. The test compounds were seria...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2G163WGUS Patent
TargetTyrosine-protein kinase TXK(Homo sapiens (Human))
GB005, Inc.

US Patent
LigandPNGBDBM50458596(CHEMBL4216187 | US10752615, Compound 50)copy SMILEScopy InChI
Affinity DataIC50: 0.25nMAssay Description:Inhibition of TXK (unknown origin) using fluorescently labeled peptide as substrate after 3 hrs by microfluidic mobility shift assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22V2JQNPubMed
TargetTyrosine-protein kinase TXK(Homo sapiens (Human))
GB005, Inc.

US Patent
LigandPNGBDBM458164(US10752615, Compound 56)copy SMILEScopy InChI
Affinity DataIC50: 0.260nMAssay Description:The in vitro kinase assays were performed at Nanosyn (Santa Clara, Calif.) utilizing microfluidic detection technology. The test compounds were seria...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2G163WGUS Patent
TargetTyrosine-protein kinase TXK(Homo sapiens (Human))
GB005, Inc.

US Patent
LigandPNGBDBM458180(US10752615, Compound 73)copy SMILEScopy InChI
Affinity DataIC50: 0.260nMAssay Description:The in vitro kinase assays were performed at Nanosyn (Santa Clara, Calif.) utilizing microfluidic detection technology. The test compounds were seria...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2G163WGUS Patent
TargetTyrosine-protein kinase TXK(Homo sapiens (Human))
GB005, Inc.

US Patent
LigandPNGBDBM458137(US10752615, Compound 29)copy SMILES
Affinity DataIC50: 0.270nMAssay Description:The in vitro kinase assays were performed at Nanosyn (Santa Clara, Calif.) utilizing microfluidic detection technology. The test compounds were seria...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2G163WGUS Patent
TargetTyrosine-protein kinase TXK(Homo sapiens (Human))
GB005, Inc.

US Patent
LigandPNGBDBM458222(US10752615, Compound 120)copy SMILEScopy InChI
Affinity DataIC50: 0.280nMAssay Description:The in vitro kinase assays were performed at Nanosyn (Santa Clara, Calif.) utilizing microfluidic detection technology. The test compounds were seria...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2G163WGUS Patent
TargetTyrosine-protein kinase TXK(Homo sapiens (Human))
GB005, Inc.

US Patent
LigandPNGBDBM458166(US10752615, Compound 58)copy SMILEScopy InChI
Affinity DataIC50: 0.290nMAssay Description:The in vitro kinase assays were performed at Nanosyn (Santa Clara, Calif.) utilizing microfluidic detection technology. The test compounds were seria...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2G163WGUS Patent
TargetTyrosine-protein kinase TXK(Homo sapiens (Human))
GB005, Inc.

US Patent
LigandPNGBDBM50458593(CHEMBL4204572 | US10752615, Compound 30)copy SMILEScopy InChI
Affinity DataIC50: 0.290nMAssay Description:The in vitro kinase assays were performed at Nanosyn (Santa Clara, Calif.) utilizing microfluidic detection technology. The test compounds were seria...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2G163WGUS Patent
TargetTyrosine-protein kinase TXK(Homo sapiens (Human))
GB005, Inc.

US Patent
LigandPNGBDBM50458593(CHEMBL4204572 | US10752615, Compound 30)copy SMILEScopy InChI
Affinity DataIC50: 0.290nMAssay Description:Inhibition of TXK (unknown origin) using fluorescently labeled peptide as substrate after 3 hrs by microfluidic mobility shift assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22V2JQNPubMed
TargetTyrosine-protein kinase TXK(Homo sapiens (Human))
GB005, Inc.

US Patent
LigandPNGBDBM458243(US10752615, Compound 141)copy SMILEScopy InChI
Affinity DataIC50: 0.290nMAssay Description:The in vitro kinase assays were performed at Nanosyn (Santa Clara, Calif.) utilizing microfluidic detection technology. The test compounds were seria...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2G163WGUS Patent
TargetTyrosine-protein kinase TXK(Homo sapiens (Human))
GB005, Inc.

US Patent
LigandPNGBDBM13216(BMS-354825 | CHEMBL1421 | DASATINIB | N-(2-Chloro-...)copy SMILEScopy InChI
Affinity DataIC50: 0.300nMAssay Description:Inhibition of TXKMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22Z15R6PubMed
TargetTyrosine-protein kinase TXK(Homo sapiens (Human))
GB005, Inc.

US Patent
LigandPNGBDBM384538((R)-N-(1-((1-acryloylpyrrolidin-2-yl)methyl)-5-(((...)copy SMILEScopy InChI
Affinity DataIC50: 0.300nMAssay Description:The ability of the compounds of the present disclosure to inhibit ITK was measured using the Caliper assay format, which is an electrophoretic separa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q21Z46RFUS Patent
TargetTyrosine-protein kinase TXK(Homo sapiens (Human))
GB005, Inc.

US Patent
LigandPNGBDBM458162(US10752615, Compound 54)copy SMILEScopy InChI
Affinity DataIC50: 0.300nMAssay Description:The in vitro kinase assays were performed at Nanosyn (Santa Clara, Calif.) utilizing microfluidic detection technology. The test compounds were seria...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2G163WGUS Patent
TargetTyrosine-protein kinase TXK(Homo sapiens (Human))
GB005, Inc.

US Patent
LigandPNGBDBM384542(N-(1-(((R)-1-acryloylpyrrolidin-2-yl)methyl)-5-(((...)copy SMILEScopy InChI
Affinity DataIC50: 0.300nMAssay Description:The ability of the compounds of the present disclosure to inhibit ITK was measured using the Caliper assay format, which is an electrophoretic separa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q21Z46RFUS Patent
TargetTyrosine-protein kinase TXK(Homo sapiens (Human))
GB005, Inc.

US Patent
LigandPNGBDBM384543((R)-N-(1-((1-acryloylpyrrolidin-2-yl)methyl)-5-(((...)copy SMILEScopy InChI
Affinity DataIC50: 0.300nMAssay Description:The ability of the compounds of the present disclosure to inhibit ITK was measured using the Caliper assay format, which is an electrophoretic separa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q21Z46RFUS Patent
TargetTyrosine-protein kinase TXK(Homo sapiens (Human))
GB005, Inc.

US Patent
LigandPNGBDBM384541(N-(1-(((R)-1-acryloylpyrrolidin-2-yl)methyl)-5-(((...)copy SMILEScopy InChI
Affinity DataIC50: 0.300nMAssay Description:The ability of the compounds of the present disclosure to inhibit ITK was measured using the Caliper assay format, which is an electrophoretic separa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q21Z46RFUS Patent
TargetTyrosine-protein kinase TXK(Homo sapiens (Human))
GB005, Inc.

US Patent
LigandPNGBDBM458202(US10752615, Compound 98)copy SMILEScopy InChI
Affinity DataIC50: 0.310nMAssay Description:The in vitro kinase assays were performed at Nanosyn (Santa Clara, Calif.) utilizing microfluidic detection technology. The test compounds were seria...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2G163WGUS Patent
TargetTyrosine-protein kinase TXK(Homo sapiens (Human))
GB005, Inc.

US Patent
LigandPNGBDBM50458603(CHEMBL4216529 | US10752615, Compound 42)copy SMILEScopy InChI
Affinity DataIC50: 0.320nMAssay Description:Inhibition of TXK (unknown origin) using fluorescently labeled peptide as substrate after 3 hrs by microfluidic mobility shift assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22V2JQNPubMed
TargetTyrosine-protein kinase TXK(Homo sapiens (Human))
GB005, Inc.

US Patent
LigandPNGBDBM458151(US10752615, Compound 43)copy SMILEScopy InChI
Affinity DataIC50: 0.320nMAssay Description:The in vitro kinase assays were performed at Nanosyn (Santa Clara, Calif.) utilizing microfluidic detection technology. The test compounds were seria...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2G163WGUS Patent
TargetTyrosine-protein kinase TXK(Homo sapiens (Human))
GB005, Inc.

US Patent
LigandPNGBDBM50458603(CHEMBL4216529 | US10752615, Compound 42)copy SMILEScopy InChI
Affinity DataIC50: 0.320nMAssay Description:The in vitro kinase assays were performed at Nanosyn (Santa Clara, Calif.) utilizing microfluidic detection technology. The test compounds were seria...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2G163WGUS Patent
TargetTyrosine-protein kinase TXK(Homo sapiens (Human))
GB005, Inc.

US Patent
LigandPNGBDBM458141(US10752615, Compound 33)copy SMILEScopy InChI
Affinity DataIC50: 0.320nMAssay Description:The in vitro kinase assays were performed at Nanosyn (Santa Clara, Calif.) utilizing microfluidic detection technology. The test compounds were seria...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2G163WGUS Patent
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