Compile Data Set for Download or QSAR

Found 26 hits of affinity data for UniProtKB/TrEMBL: O75342   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Arachidonate 12-lipoxygenase, 12R-type (Homo sapiens (Human))	BDBM86010 (Chalcone, 10) Show SMILES Oc1ccc(Cl)cc1C(=O)\C=C\c1ccccc1 Show InChI InChI=1S/C15H11ClO2/c16-12-7-9-15(18)13(10-12)14(17)8-6-11-4-2-1-3-5-11/h1-10,18H/b8-6+	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	5.76E+4	-24.2	n/a	n/a	n/a	n/a	n/a	8.0	25
Quaid-i-Azam University					Assay Description In vitro lipoxygenase inhibition assay, lipoxygenase inhibiting activity was convenintly measured by slightly modifying the spectrometic method devel...				J Enzyme Inhib Med Chem 20: 41-7 (2005) Article DOI: 10.1080/14756360400015231 BindingDB Entry DOI: 10.7270/Q2FX781C
					More data for this Ligand-Target Pair
Arachidonate 12-lipoxygenase, 12R-type (Homo sapiens (Human))	BDBM86012 (Chalcone, 11) Show SMILES Oc1ccc(Cl)cc1C(=O)\C=C\c1ccc(Cl)cc1 Show InChI InChI=1S/C15H10Cl2O2/c16-11-4-1-10(2-5-11)3-7-14(18)13-9-12(17)6-8-15(13)19/h1-9,19H/b7-3+	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	7.17E+4	-23.7	n/a	n/a	n/a	n/a	n/a	8.0	25
Quaid-i-Azam University					Assay Description In vitro lipoxygenase inhibition assay, lipoxygenase inhibiting activity was convenintly measured by slightly modifying the spectrometic method devel...				J Enzyme Inhib Med Chem 20: 41-7 (2005) Article DOI: 10.1080/14756360400015231 BindingDB Entry DOI: 10.7270/Q2FX781C
					More data for this Ligand-Target Pair
Arachidonate 12-lipoxygenase, 12R-type (Homo sapiens (Human))	BDBM86082 (Tetraketone, 19) Show SMILES CC1(C)CC(=O)C(C(C2C(=O)CC(C)(C)CC2=O)c2ccc(\C=C\c3ccccc3)cc2)C(=O)C1 Show InChI InChI=1S/C31H34O4/c1-30(2)16-23(32)28(24(33)17-30)27(29-25(34)18-31(3,4)19-26(29)35)22-14-12-21(13-15-22)11-10-20-8-6-5-7-9-20/h5-15,27-29H,16-19H2,1-4H3/b11-10+	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	7.80E+3	n/a	n/a	n/a	n/a	8.0	25
Pharmaceutical Research Centre					Assay Description In vitro liposygenase inhibition assay activity was measured by modifying the spectrophotometric method developed by Tappel. The compound was prepar...				J Enzyme Inhib Med Chem 23: 62-9 (2008) Article DOI: 10.1080/14756360701408754 BindingDB Entry DOI: 10.7270/Q2P849FN
					More data for this Ligand-Target Pair
Arachidonate 12-lipoxygenase, 12R-type (Homo sapiens (Human))	BDBM86085 (Tetraketone, 22) Show SMILES Cc1ccc(o1)C(C1C(=O)CC(C)(C)CC1=O)C1C(=O)CC(C)(C)CC1=O Show InChI InChI=1S/C22H28O5/c1-12-6-7-17(27-12)20(18-13(23)8-21(2,3)9-14(18)24)19-15(25)10-22(4,5)11-16(19)26/h6-7,18-20H,8-11H2,1-5H3	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.25E+4	n/a	n/a	n/a	n/a	8.0	25
Pharmaceutical Research Centre					Assay Description In vitro liposygenase inhibition assay activity was measured by modifying the spectrophotometric method developed by Tappel. The compound was prepar...				J Enzyme Inhib Med Chem 23: 62-9 (2008) Article DOI: 10.1080/14756360701408754 BindingDB Entry DOI: 10.7270/Q2P849FN
					More data for this Ligand-Target Pair
Arachidonate 12-lipoxygenase, 12R-type (Homo sapiens (Human))	BDBM86070 (Tetraketone, 3) Show SMILES Cc1ccc(cc1)C(C1C(=O)CC(C)(C)CC1=O)C1C(=O)CC(C)(C)CC1=O Show InChI InChI=1S/C24H30O4/c1-14-6-8-15(9-7-14)20(21-16(25)10-23(2,3)11-17(21)26)22-18(27)12-24(4,5)13-19(22)28/h6-9,20-22H,10-13H2,1-5H3	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.63E+4	n/a	n/a	n/a	n/a	8.0	25
Pharmaceutical Research Centre					Assay Description In vitro liposygenase inhibition assay activity was measured by modifying the spectrophotometric method developed by Tappel. The compound was prepar...				J Enzyme Inhib Med Chem 23: 62-9 (2008) Article DOI: 10.1080/14756360701408754 BindingDB Entry DOI: 10.7270/Q2P849FN
					More data for this Ligand-Target Pair
Arachidonate 12-lipoxygenase, 12R-type (Homo sapiens (Human))	BDBM86077 (Tetraketone, 11) Show SMILES CN(C)c1ccc(cc1)C(C1C(=O)CC(C)(C)CC1=O)C1C(=O)CC(C)(C)CC1=O Show InChI InChI=1S/C25H33NO4/c1-24(2)11-17(27)22(18(28)12-24)21(15-7-9-16(10-8-15)26(5)6)23-19(29)13-25(3,4)14-20(23)30/h7-10,21-23H,11-14H2,1-6H3	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.75E+4	n/a	n/a	n/a	n/a	8.0	25
Pharmaceutical Research Centre					Assay Description In vitro liposygenase inhibition assay activity was measured by modifying the spectrophotometric method developed by Tappel. The compound was prepar...				J Enzyme Inhib Med Chem 23: 62-9 (2008) Article DOI: 10.1080/14756360701408754 BindingDB Entry DOI: 10.7270/Q2P849FN
					More data for this Ligand-Target Pair
Arachidonate 12-lipoxygenase, 12R-type (Homo sapiens (Human))	BDBM86074 (Tetraketone, 8) Show SMILES COc1ccc(cc1)C(C1C(=O)CC(C)(C)CC1=O)C1C(=O)CC(C)(C)CC1=O Show InChI InChI=1S/C24H30O5/c1-23(2)10-16(25)21(17(26)11-23)20(14-6-8-15(29-5)9-7-14)22-18(27)12-24(3,4)13-19(22)28/h6-9,20-22H,10-13H2,1-5H3	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.13E+4	n/a	n/a	n/a	n/a	8.0	25
Pharmaceutical Research Centre					Assay Description In vitro liposygenase inhibition assay activity was measured by modifying the spectrophotometric method developed by Tappel. The compound was prepar...				J Enzyme Inhib Med Chem 23: 62-9 (2008) Article DOI: 10.1080/14756360701408754 BindingDB Entry DOI: 10.7270/Q2P849FN
					More data for this Ligand-Target Pair
Arachidonate 12-lipoxygenase, 12R-type (Homo sapiens (Human))	BDBM86072 (Tetraketone, 6) Show SMILES CC1(C)CC(=O)C(C(C2C(=O)CC(C)(C)CC2=O)c2ccc(O)cc2)C(=O)C1 Show InChI InChI=1S/C23H28O5/c1-22(2)9-15(25)20(16(26)10-22)19(13-5-7-14(24)8-6-13)21-17(27)11-23(3,4)12-18(21)28/h5-8,19-21,24H,9-12H2,1-4H3	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.64E+4	n/a	n/a	n/a	n/a	8.0	25
Pharmaceutical Research Centre					Assay Description In vitro liposygenase inhibition assay activity was measured by modifying the spectrophotometric method developed by Tappel. The compound was prepar...				J Enzyme Inhib Med Chem 23: 62-9 (2008) Article DOI: 10.1080/14756360701408754 BindingDB Entry DOI: 10.7270/Q2P849FN
					More data for this Ligand-Target Pair
Arachidonate 12-lipoxygenase, 12R-type (Homo sapiens (Human))	BDBM86080 (Tetraketone, 15) Show SMILES CC1(C)CC(=O)C(C(C2C(=O)CC(C)(C)CC2=O)c2ccc(O)c(Br)c2)C(=O)C1 Show InChI InChI=1S/C23H27BrO5/c1-22(2)8-15(26)20(16(27)9-22)19(12-5-6-14(25)13(24)7-12)21-17(28)10-23(3,4)11-18(21)29/h5-7,19-21,25H,8-11H2,1-4H3	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.71E+4	n/a	n/a	n/a	n/a	8.0	25
Pharmaceutical Research Centre					Assay Description In vitro liposygenase inhibition assay activity was measured by modifying the spectrophotometric method developed by Tappel. The compound was prepar...				J Enzyme Inhib Med Chem 23: 62-9 (2008) Article DOI: 10.1080/14756360701408754 BindingDB Entry DOI: 10.7270/Q2P849FN
					More data for this Ligand-Target Pair
Arachidonate 12-lipoxygenase, 12R-type (Homo sapiens (Human))	BDBM86078 (Tetraketone, 12) Show SMILES CC1(C)CC(=O)C(C(C2C(=O)CC(C)(C)CC2=O)c2ccccc2Cl)C(=O)C1 Show InChI InChI=1S/C23H27ClO4/c1-22(2)9-15(25)20(16(26)10-22)19(13-7-5-6-8-14(13)24)21-17(27)11-23(3,4)12-18(21)28/h5-8,19-21H,9-12H2,1-4H3	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.84E+4	n/a	n/a	n/a	n/a	8.0	25
Pharmaceutical Research Centre					Assay Description In vitro liposygenase inhibition assay activity was measured by modifying the spectrophotometric method developed by Tappel. The compound was prepar...				J Enzyme Inhib Med Chem 23: 62-9 (2008) Article DOI: 10.1080/14756360701408754 BindingDB Entry DOI: 10.7270/Q2P849FN
					More data for this Ligand-Target Pair
Arachidonate 12-lipoxygenase, 12R-type (Homo sapiens (Human))	BDBM86076 (Tetraketone, 10) Show SMILES CCOc1ccc(cc1)C(C1C(=O)CC(C)(C)CC1=O)C1C(=O)CC(C)(C)CC1=O Show InChI InChI=1S/C25H32O5/c1-6-30-16-9-7-15(8-10-16)21(22-17(26)11-24(2,3)12-18(22)27)23-19(28)13-25(4,5)14-20(23)29/h7-10,21-23H,6,11-14H2,1-5H3	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.08E+4	n/a	n/a	n/a	n/a	8.0	25
Pharmaceutical Research Centre					Assay Description In vitro liposygenase inhibition assay activity was measured by modifying the spectrophotometric method developed by Tappel. The compound was prepar...				J Enzyme Inhib Med Chem 23: 62-9 (2008) Article DOI: 10.1080/14756360701408754 BindingDB Entry DOI: 10.7270/Q2P849FN
					More data for this Ligand-Target Pair
Arachidonate 12-lipoxygenase, 12R-type (Homo sapiens (Human))	BDBM86069 (Tetraketone, 2) Show SMILES CC1(C)CC(=O)C(C(C2C(=O)CC(C)(C)CC2=O)c2ccccc2)C(=O)C1 Show InChI InChI=1S/C23H28O4/c1-22(2)10-15(24)20(16(25)11-22)19(14-8-6-5-7-9-14)21-17(26)12-23(3,4)13-18(21)27/h5-9,19-21H,10-13H2,1-4H3	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.30E+4	n/a	n/a	n/a	n/a	8.0	25
Pharmaceutical Research Centre					Assay Description In vitro liposygenase inhibition assay activity was measured by modifying the spectrophotometric method developed by Tappel. The compound was prepar...				J Enzyme Inhib Med Chem 23: 62-9 (2008) Article DOI: 10.1080/14756360701408754 BindingDB Entry DOI: 10.7270/Q2P849FN
					More data for this Ligand-Target Pair
Arachidonate 12-lipoxygenase, 12R-type (Homo sapiens (Human))	BDBM86075 (Tetraketone, 9) Show SMILES COc1ccc(C(C2C(=O)CC(C)(C)CC2=O)C2C(=O)CC(C)(C)CC2=O)c(OC)c1 Show InChI InChI=1S/C25H32O6/c1-24(2)10-16(26)22(17(27)11-24)21(15-8-7-14(30-5)9-20(15)31-6)23-18(28)12-25(3,4)13-19(23)29/h7-9,21-23H,10-13H2,1-6H3	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.31E+4	n/a	n/a	n/a	n/a	8.0	25
Pharmaceutical Research Centre					Assay Description In vitro liposygenase inhibition assay activity was measured by modifying the spectrophotometric method developed by Tappel. The compound was prepar...				J Enzyme Inhib Med Chem 23: 62-9 (2008) Article DOI: 10.1080/14756360701408754 BindingDB Entry DOI: 10.7270/Q2P849FN
					More data for this Ligand-Target Pair
Arachidonate 12-lipoxygenase, 12R-type (Homo sapiens (Human))	BDBM86083 (Tetraketone, 20) Show SMILES CC1(C)CC(=O)C(C(C2C(=O)CC(C)(C)CC2=O)c2ccc(cc2)C(\Br)=C\c2ccccc2)C(=O)C1 Show InChI InChI=1S/C31H33BrO4/c1-30(2)15-23(33)28(24(34)16-30)27(29-25(35)17-31(3,4)18-26(29)36)21-12-10-20(11-13-21)22(32)14-19-8-6-5-7-9-19/h5-14,27-29H,15-18H2,1-4H3/b22-14-	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.54E+4	n/a	n/a	n/a	n/a	8.0	25
Pharmaceutical Research Centre					Assay Description In vitro liposygenase inhibition assay activity was measured by modifying the spectrophotometric method developed by Tappel. The compound was prepar...				J Enzyme Inhib Med Chem 23: 62-9 (2008) Article DOI: 10.1080/14756360701408754 BindingDB Entry DOI: 10.7270/Q2P849FN
					More data for this Ligand-Target Pair
Arachidonate 12-lipoxygenase, 12R-type (Homo sapiens (Human))	BDBM86087 (Buddlejoside B, 2) Show SMILES OCC1OC(O[C@@H]2OC=C[C@H]3[C@H](O)C=C(COC(=O)c4ccc(O)c(O)c4)[C@@H]23)C(O)C(O)C1O |r,c:8,t:13| Show InChI InChI=1S/C22H26O12/c23-7-15-17(27)18(28)19(29)22(33-15)34-21-16-10(6-13(25)11(16)3-4-31-21)8-32-20(30)9-1-2-12(24)14(26)5-9/h1-6,11,13,15-19,21-29H,7-8H2/t11-,13+,15?,16+,17?,18?,19?,21-,22?/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.97E+4	n/a	n/a	n/a	n/a	8.0	25
Chinese Academy of Medical Sciences					Assay Description Lipoxygenase inhibiting activity was measured by slightly modifying the spectrometric method. Lipoxygenase type I-B and linoleic acid were purchased...				J Enzyme Inhib Med Chem 23: 140-3 (2008) Article DOI: 10.1080/14756360701342532 BindingDB Entry DOI: 10.7270/Q2JH3JRC
					More data for this Ligand-Target Pair
Arachidonate 12-lipoxygenase, 12R-type (Homo sapiens (Human))	BDBM86092 (Buddlejoside A5, 7) Show SMILES COc1ccc(\C=C\C(=O)OC2C(O)C(C)OC(O[C@@H]3[C@@H]4O[C@]4(CO)C4C3C=CO[C@H]4OC3OC(CO)C(O)C(O)C3O)C2OC(C)=O)cc1 |r,c:29| Show InChI InChI=1S/C33H42O17/c1-14-22(38)27(47-20(37)9-6-16-4-7-17(42-3)8-5-16)28(45-15(2)36)32(44-14)48-26-18-10-11-43-30(21(18)33(13-35)29(26)50-33)49-31-25(41)24(40)23(39)19(12-34)46-31/h4-11,14,18-19,21-32,34-35,38-41H,12-13H2,1-3H3/b9-6+/t14?,18?,19?,21?,22?,23?,24?,25?,26-,27?,28?,29-,30-,31?,32?,33+/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.04E+4	n/a	n/a	n/a	n/a	8.0	25
Chinese Academy of Medical Sciences					Assay Description Lipoxygenase inhibiting activity was measured by slightly modifying the spectrometric method. Lipoxygenase type I-B and linoleic acid were purchased...				J Enzyme Inhib Med Chem 23: 140-3 (2008) Article DOI: 10.1080/14756360701342532 BindingDB Entry DOI: 10.7270/Q2JH3JRC
					More data for this Ligand-Target Pair
Arachidonate 12-lipoxygenase, 12R-type (Homo sapiens (Human))	BDBM86091 (Buddlejoside A2, 6) Show SMILES COc1ccc(\C=C\C(=O)OC2C(C)OC(O[C@@H]3C=C(CO)C4C3C=CO[C@H]4OC3OC(CO)C(O)C(O)C3O)C(OC(C)=O)C2O)cc1 |r,c:25,t:18| Show InChI InChI=1S/C33H42O16/c1-15-29(48-23(37)9-6-17-4-7-19(42-3)8-5-17)28(41)30(45-16(2)36)33(44-15)46-21-12-18(13-34)24-20(21)10-11-43-31(24)49-32-27(40)26(39)25(38)22(14-35)47-32/h4-12,15,20-22,24-35,38-41H,13-14H2,1-3H3/b9-6+/t15?,20?,21-,22?,24?,25?,26?,27?,28?,29?,30?,31+,32?,33?/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.19E+4	n/a	n/a	n/a	n/a	8.0	25
Chinese Academy of Medical Sciences					Assay Description Lipoxygenase inhibiting activity was measured by slightly modifying the spectrometric method. Lipoxygenase type I-B and linoleic acid were purchased...				J Enzyme Inhib Med Chem 23: 140-3 (2008) Article DOI: 10.1080/14756360701342532 BindingDB Entry DOI: 10.7270/Q2JH3JRC
					More data for this Ligand-Target Pair
Arachidonate 12-lipoxygenase, 12R-type (Homo sapiens (Human))	BDBM86086 (Buddlejoside A, 1) Show SMILES OCC1OC(O[C@@H]2OC=C[C@H]3[C@H](O)C=C(COC(=O)c4ccc(O)cc4)[C@@H]23)C(O)C(O)C1O |r,c:8,t:13| Show InChI InChI=1S/C22H26O11/c23-8-15-17(26)18(27)19(28)22(32-15)33-21-16-11(7-14(25)13(16)5-6-30-21)9-31-20(29)10-1-3-12(24)4-2-10/h1-7,13-19,21-28H,8-9H2/t13-,14+,15?,16+,17?,18?,19?,21-,22?/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	4.43E+4	n/a	n/a	n/a	n/a	8.0	25
Chinese Academy of Medical Sciences					Assay Description Lipoxygenase inhibiting activity was measured by slightly modifying the spectrometric method. Lipoxygenase type I-B and linoleic acid were purchased...				J Enzyme Inhib Med Chem 23: 140-3 (2008) Article DOI: 10.1080/14756360701342532 BindingDB Entry DOI: 10.7270/Q2JH3JRC
					More data for this Ligand-Target Pair
Arachidonate 12-lipoxygenase, 12R-type (Homo sapiens (Human))	BDBM86090 (Beta-gardiol, 5) Show SMILES COC(=O)[C@@H]1C2C=C[C@@]3(O)CO[C@@H](O[C@@H]1O)C23 |r,c:6| Show InChI InChI=1S/C11H14O6/c1-15-8(12)6-5-2-3-11(14)4-16-10(7(5)11)17-9(6)13/h2-3,5-7,9-10,13-14H,4H2,1H3/t5?,6-,7?,9-,10-,11+/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.73E+4	n/a	n/a	n/a	n/a	8.0	25
Chinese Academy of Medical Sciences					Assay Description Lipoxygenase inhibiting activity was measured by slightly modifying the spectrometric method. Lipoxygenase type I-B and linoleic acid were purchased...				J Enzyme Inhib Med Chem 23: 140-3 (2008) Article DOI: 10.1080/14756360701342532 BindingDB Entry DOI: 10.7270/Q2JH3JRC
					More data for this Ligand-Target Pair
Arachidonate 12-lipoxygenase, 12R-type (Homo sapiens (Human))	BDBM86089 (Genipin, 4) Show SMILES COC(=O)C1=CO[C@@H](O)C2C(CO)C=CC12 |r,c:13,t:4| Show InChI InChI=1S/C11H14O5/c1-15-10(13)8-5-16-11(14)9-6(4-12)2-3-7(8)9/h2-3,5-7,9,11-12,14H,4H2,1H3/t6?,7?,9?,11-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.96E+4	n/a	n/a	n/a	n/a	8.0	25
Chinese Academy of Medical Sciences					Assay Description Lipoxygenase inhibiting activity was measured by slightly modifying the spectrometric method. Lipoxygenase type I-B and linoleic acid were purchased...				J Enzyme Inhib Med Chem 23: 140-3 (2008) Article DOI: 10.1080/14756360701342532 BindingDB Entry DOI: 10.7270/Q2JH3JRC
					More data for this Ligand-Target Pair
Arachidonate 12-lipoxygenase, 12R-type (Homo sapiens (Human))	BDBM86084 (Tetraketone, 21) Show SMILES CC1(C)CC(=O)C(C(C2C(=O)CC(C)(C)CC2=O)c2ccco2)C(=O)C1 Show InChI InChI=1S/C21H26O5/c1-20(2)8-12(22)17(13(23)9-20)19(16-6-5-7-26-16)18-14(24)10-21(3,4)11-15(18)25/h5-7,17-19H,8-11H2,1-4H3	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.15E+4	n/a	n/a	n/a	n/a	8.0	25
Pharmaceutical Research Centre					Assay Description In vitro liposygenase inhibition assay activity was measured by modifying the spectrophotometric method developed by Tappel. The compound was prepar...				J Enzyme Inhib Med Chem 23: 62-9 (2008) Article DOI: 10.1080/14756360701408754 BindingDB Entry DOI: 10.7270/Q2P849FN
					More data for this Ligand-Target Pair
Arachidonate 12-lipoxygenase, 12R-type (Homo sapiens (Human))	BDBM86088 (Buddlejoside C, 3) Show SMILES CC(C)CC(=O)OCC1=C[C@@H](O)[C@@H]2C=CC[C@H](OC3OC(CO)C(O)C(O)C3O)[C@H]12 |r,c:13,t:8| Show InChI InChI=1S/C21H32O9/c1-10(2)6-16(24)28-9-11-7-13(23)12-4-3-5-14(17(11)12)29-21-20(27)19(26)18(25)15(8-22)30-21/h3-4,7,10,12-15,17-23,25-27H,5-6,8-9H2,1-2H3/t12-,13+,14-,15?,17+,18?,19?,20?,21?/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.25E+4	n/a	n/a	n/a	n/a	8.0	25
Chinese Academy of Medical Sciences					Assay Description Lipoxygenase inhibiting activity was measured by slightly modifying the spectrometric method. Lipoxygenase type I-B and linoleic acid were purchased...				J Enzyme Inhib Med Chem 23: 140-3 (2008) Article DOI: 10.1080/14756360701342532 BindingDB Entry DOI: 10.7270/Q2JH3JRC
					More data for this Ligand-Target Pair
Arachidonate 12-lipoxygenase, 12R-type (Homo sapiens (Human))	BDBM86079 (Tetraketone, 14) Show SMILES CC1(C)CC(=O)C(C(C2C(=O)CC(C)(C)CC2=O)c2cccc(Br)c2)C(=O)C1 Show InChI InChI=1S/C23H27BrO4/c1-22(2)9-15(25)20(16(26)10-22)19(13-6-5-7-14(24)8-13)21-17(27)11-23(3,4)12-18(21)28/h5-8,19-21H,9-12H2,1-4H3	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.29E+4	n/a	n/a	n/a	n/a	8.0	25
Pharmaceutical Research Centre					Assay Description In vitro liposygenase inhibition assay activity was measured by modifying the spectrophotometric method developed by Tappel. The compound was prepar...				J Enzyme Inhib Med Chem 23: 62-9 (2008) Article DOI: 10.1080/14756360701408754 BindingDB Entry DOI: 10.7270/Q2P849FN
					More data for this Ligand-Target Pair
Arachidonate 12-lipoxygenase, 12R-type (Homo sapiens (Human))	BDBM86081 (Tetraketone, 16) Show SMILES CC1(C)CC(=O)C(C(C2C(=O)CC(C)(C)CC2=O)c2ccccc2N(=O)=O)C(=O)C1 Show InChI InChI=1S/C23H27NO6/c1-22(2)9-15(25)20(16(26)10-22)19(13-7-5-6-8-14(13)24(29)30)21-17(27)11-23(3,4)12-18(21)28/h5-8,19-21H,9-12H2,1-4H3	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.91E+5	n/a	n/a	n/a	n/a	8.0	25
Pharmaceutical Research Centre					Assay Description In vitro liposygenase inhibition assay activity was measured by modifying the spectrophotometric method developed by Tappel. The compound was prepar...				J Enzyme Inhib Med Chem 23: 62-9 (2008) Article DOI: 10.1080/14756360701408754 BindingDB Entry DOI: 10.7270/Q2P849FN
					More data for this Ligand-Target Pair
Arachidonate 12-lipoxygenase, 12R-type (Homo sapiens (Human))	BDBM86073 (Tetraketone, 7) Show SMILES COc1ccccc1C(C1C(=O)CC(C)(C)CC1=O)C1C(=O)CC(C)(C)CC1=O Show InChI InChI=1S/C24H30O5/c1-23(2)10-15(25)21(16(26)11-23)20(14-8-6-7-9-19(14)29-5)22-17(27)12-24(3,4)13-18(22)28/h6-9,20-22H,10-13H2,1-5H3	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.96E+5	n/a	n/a	n/a	n/a	8.0	25
Pharmaceutical Research Centre					Assay Description In vitro liposygenase inhibition assay activity was measured by modifying the spectrophotometric method developed by Tappel. The compound was prepar...				J Enzyme Inhib Med Chem 23: 62-9 (2008) Article DOI: 10.1080/14756360701408754 BindingDB Entry DOI: 10.7270/Q2P849FN
					More data for this Ligand-Target Pair
Arachidonate 12-lipoxygenase, 12R-type (Homo sapiens (Human))	BDBM86071 (Tetraketone, 4) Show SMILES CC1(C)CC(=O)C(C(C2C(=O)CC(C)(C)CC2=O)c2ccccc2O)C(=O)C1 Show InChI InChI=1S/C23H28O5/c1-22(2)9-15(25)20(16(26)10-22)19(13-7-5-6-8-14(13)24)21-17(27)11-23(3,4)12-18(21)28/h5-8,19-21,24H,9-12H2,1-4H3	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.98E+5	n/a	n/a	n/a	n/a	8.0	25
Pharmaceutical Research Centre					Assay Description In vitro liposygenase inhibition assay activity was measured by modifying the spectrophotometric method developed by Tappel. The compound was prepar...				J Enzyme Inhib Med Chem 23: 62-9 (2008) Article DOI: 10.1080/14756360701408754 BindingDB Entry DOI: 10.7270/Q2P849FN
					More data for this Ligand-Target Pair