The following articles (labelled with PubMed ID or TBD) are for your review
PMID | Data | Article Title | Organization |
28085283 |
118 |
Design, Synthesis, and Biological Evaluation of Novel, Non-Brain-Penetrant, Hybrid Cannabinoid CB |
National Institute On Alcohol Abuse and Alcoholism |
8411021 |
3 |
Two new unsaturated fatty acid ethanolamides in brain that bind to the cannabinoid receptor. |
Hebrew University |
27240274 |
37 |
A critical review of both the synthesis approach and the receptor profile of the 8-chloro-1-(2',4'-dichlorophenyl)-N-piperidin-1-yl-1,4,5,6-tetrahydrobenzo[6,7]cyclohepta[1,2-c]pyrazole-3-carboxamide and analogue derivatives. |
Neuroscienze Pharmaness S.C.A R.L. |
26200936 |
39 |
Applications of Fluorine in Medicinal Chemistry. |
Bristol-Myers Squibb Research and Development |
22904561 |
6 |
Cytochrome P450-mediated oxidative metabolism of abused synthetic cannabinoids found in K2/Spice: identification of novel cannabinoid receptor ligands. |
University of Arkansas For Medical Sciences |
25703248 |
3 |
Cannabidiol (CBD) and its analogs: a review of their effects on inflammation. |
University of Massachusetts Medical School |
25134064 |
40 |
Tricyclic pyrazoles part 7. Discovery of potent and selective dihydrothienocyclopentapyrazole derived CB2 ligands. |
Universit£ |
25488844 |
154 |
Discovery of 1a,2,5,5a-tetrahydro-1H-2,3-diaza-cyclopropa[a]pentalen-4-carboxamides as potent and selective CB2 receptor agonists. |
Arena Pharmaceuticals |
24922543 |
24 |
Tricyclic pyrazoles. Part 6. Benzofuro[3,2-c]pyrazole: a versatile architecture for CB2 selective ligands. |
Universit£ |
23865723 |
169 |
Therapeutic utility of cannabinoid receptor type 2 (CB(2)) selective agonists. |
Arena Pharmaceuticals |
23466226 |
26 |
Evaluation of (Z)-2-((1-benzyl-1H-indol-3-yl)methylene)-quinuclidin-3-one analogues as novel, high affinity ligands for CB1 and CB2 cannabinoid receptors. |
University of Arkansas For Medical Sciences |
23380378 |
127 |
Highly potent and selective cannabinoid receptor 2 agonists: initial hit optimization of an adamantyl hit series identified from high-through-put screening. |
F. Hoffmann-La Roche |
23357307 |
14 |
Novel pyrazole derivatives as neutral CB1 antagonists with significant activity towards food intake. |
Neuroscienze Pharmaness S.C.A R.L. |
17149879 |
40 |
Tricyclic pyrazoles. 4. Synthesis and biological evaluation of analogues of the robust and selective CB2 cannabinoid ligand 1-(2',4'-dichlorophenyl)-6-methyl-N-piperidin-1-yl-1,4-dihydroindeno[1,2-c]pyrazole-3-carboxamide. |
Universit£ |
17004710 |
51 |
Design, synthesis, and biological evaluation of new 1,8-naphthyridin-4(1H)-on-3-carboxamide and quinolin-4(1H)-on-3-carboxamide derivatives as CB2 selective agonists. |
Universit£ |
16190764 |
24 |
Potent cannabinergic indole analogues as radioiodinatable brain imaging agents for the CB1 cannabinoid receptor. |
Northeastern University |
16078824 |
48 |
The endocannabinoid system: drug targets, lead compounds, and potential therapeutic applications. |
Universit£ |
9357528 |
26 |
Potent anandamide analogs: the effect of changing the length and branching of the end pentyl chain. |
Organix |
22284817 |
82 |
¿-Carbolines: a novel class of cannabinoid agonists with high aqueous solubility and restricted CNS penetration. |
Astrazeneca R&D Montreal |
22044209 |
56 |
Resorcinol-sn-glycerol derivatives: novel 2-arachidonoylglycerol mimetics endowed with high affinity and selectivity for cannabinoid type 1 receptor. |
Universit£ |
18438404 |
13 |
Activation of the endocannabinoid system by organophosphorus nerve agents. |
University of California |
20591666 |
66 |
A new group of oxime carbamates as reversible inhibitors of fatty acid amide hydrolase. |
Università |
18977140 |
43 |
2-Arylimino-5,6-dihydro-4H-1,3-thiazines as a new class of cannabinoid receptor agonists. Part 3: Synthesis and activity of isosteric analogs. |
Shionogi |
18752948 |
34 |
Monoacylglycerol lipase regulates 2-arachidonoylglycerol action and arachidonic acid levels. |
University of California |
17870539 |
9 |
Discovery of 1,1-dioxo-1,2,6-thiadiazine-5-carboxamide derivatives as cannabinoid-like molecules with agonist and antagonist activity. |
Instituto De QuíMica MéDica |
17531479 |
65 |
2-Arylimino-5,6-dihydro-4H-1,3-thiazines as a new class of cannabinoid receptor agonists. Part 2: orally bioavailable compounds. |
Shionogi |
17521907 |
50 |
2-Arylimino-5,6-dihydro-4H-1,3-thiazines as a new class of cannabinoid receptor agonists. Part 1: discovery of CB2 receptor selective compounds. |
Shionogi |
16279795 |
36 |
Tricyclic pyrazoles. 3. Synthesis, biological evaluation, and molecular modeling of analogues of the cannabinoid antagonist 8-chloro-1-(2',4'-dichlorophenyl)-N-piperidin-1-yl-1,4,5,6-tetrahydrobenzo[6,7]cyclohepta[1,2-c]pyrazole-3-carboxamide. |
Università |
12951114 |
18 |
Arachidonylsulfonyl derivatives as cannabinoid CB1 receptor and fatty acid amide hydrolase inhibitors. |
University of California |
27624523 |
33 |
Synthesis, molecular modeling and SAR study of novel pyrazolo[5,1-f][1,6]naphthyridines as CB |
Universit£ |
30816712 |
78 |
Plant-Based Modulators of Endocannabinoid Signaling. |
Concordia University Wisconsin |
31596583 |
306 |
Synthesis and Pharmacological Evaluation of 1-Phenyl-3-Thiophenylurea Derivatives as Cannabinoid Type-1 Receptor Allosteric Modulators. |
Research Triangle Institute |
31413808 |
16 |
Identification of CB1 Receptor Allosteric Sites Using Force-Biased MMC Simulated Annealing and Validation by Structure-Activity Relationship Studies. |
University of North Carolina At Greensboro |
26529344 |
22 |
Novel Electrophilic and Photoaffinity Covalent Probes for Mapping the Cannabinoid 1 Receptor Allosteric Site(s). |
Dalhousie University |
24095014 |
52 |
N-Alkyl dien- and trienamides from the roots of Otanthus maritimus with binding affinity for opioid and cannabinoid receptors. |
Uos of Cagliari |
23623258 |
36 |
Selective CB2 agonists with anti-pruritic activity: discovery of potent and orally available bicyclic 2-pyridones. |
Shionogi |
23631463 |
14 |
Design, synthesis, and biological evaluation of aminoalkylindole derivatives as cannabinoid receptor ligands with potential for treatment of alcohol abuse. |
The University of Kansas |
26575582 |
15 |
Development of 2-(Substituted Benzylamino)-4-Methyl-1, 3-Thiazole-5-Carboxylic Acid Derivatives as Xanthine Oxidase Inhibitors and Free Radical Scavengers. |
Jamia Hamdard |
9652348 |
146 |
[125I][Tyr3]octreotide labels human somatostatin sst2 and sst5 receptors. |
Novartis Pharma |