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PubMed code 24922543

Compile data set for download or QSAR
Found 24 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50200169
PNG
(6-methyl-1-(2',4'-dichlorophenyl)-N-piperidin-1-yl...)
Show SMILES Cc1ccc-2c(Cc3c(nn(c-23)-c2ccc(Cl)cc2Cl)C(=O)NN2CCCCC2)c1
Show InChI InChI=1S/C23H22Cl2N4O/c1-14-5-7-17-15(11-14)12-18-21(23(30)27-28-9-3-2-4-10-28)26-29(22(17)18)20-8-6-16(24)13-19(20)25/h5-8,11,13H,2-4,9-10,12H2,1H3,(H,27,30)
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0.0370n/an/an/an/an/an/an/an/a



Universit£ di Sassari

Curated by ChEMBL


Assay Description
Binding affinity to CB2 receptor (unknown origin)


Eur J Med Chem 82: 281-92 (2014)


Article DOI: 10.1016/j.ejmech.2014.05.055
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50180022
PNG
(5-(4-chloro-3-methyl-phenyl)-1-(4-methyl-benzyl)-1...)
Show SMILES Cc1ccc(Cn2nc(cc2-c2ccc(Cl)c(C)c2)C(=O)NC2C3(C)CCC(C3)C2(C)C)cc1 |THB:21:22:26.25:28|
Show InChI InChI=1S/C29H34ClN3O/c1-18-6-8-20(9-7-18)17-33-25(21-10-11-23(30)19(2)14-21)15-24(32-33)26(34)31-27-28(3,4)22-12-13-29(27,5)16-22/h6-11,14-15,22,27H,12-13,16-17H2,1-5H3,(H,31,34)
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0.280n/an/an/an/an/an/an/an/a



Universit£ di Sassari

Curated by ChEMBL


Assay Description
Displacement of [3H]-CP-55,940 from CB2 receptor (unknown origin)


Eur J Med Chem 82: 281-92 (2014)


Article DOI: 10.1016/j.ejmech.2014.05.055
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(MOUSE)
BDBM50020597
PNG
(CHEMBL3290447)
Show SMILES CC(C)[C@@H]1CC[C@@H](C)C[C@H]1NC(=O)c1nn(-c2ccc(Cl)cc2Cl)c2c3ccc(C)cc3oc12 |r|
Show InChI InChI=1S/C27H29Cl2N3O2/c1-14(2)18-8-5-15(3)11-21(18)30-27(33)24-26-25(19-9-6-16(4)12-23(19)34-26)32(31-24)22-10-7-17(28)13-20(22)29/h6-7,9-10,12-15,18,21H,5,8,11H2,1-4H3,(H,30,33)/t15-,18+,21-/m1/s1
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2.30n/an/an/an/an/an/an/an/a



Universit£ di Sassari

Curated by ChEMBL


Assay Description
Displacement of [3H]-CP-55,940 from CB2 receptor in CD1 mouse spleen homogenate after 1 hr by liquid scintillation counting analysis


Eur J Med Chem 82: 281-92 (2014)


Article DOI: 10.1016/j.ejmech.2014.05.055
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(MOUSE)
BDBM50020600
PNG
(CHEMBL3290450)
Show SMILES Cc1ccc2c(c1)oc1c(nn(-c3ccc(Cl)cc3Cl)c21)C(=O)N[C@H]1C2(C)CCC(C2)C1(C)C |r|
Show InChI InChI=1S/C27H27Cl2N3O2/c1-14-5-7-17-20(11-14)34-23-21(31-32(22(17)23)19-8-6-16(28)12-18(19)29)24(33)30-25-26(2,3)15-9-10-27(25,4)13-15/h5-8,11-12,15,25H,9-10,13H2,1-4H3,(H,30,33)/t15?,25-,27?/m1/s1
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2.5n/an/an/an/an/an/an/an/a



Universit£ di Sassari

Curated by ChEMBL


Assay Description
Displacement of [3H]-CP-55,940 from CB2 receptor in CD1 mouse spleen homogenate after 1 hr by liquid scintillation counting analysis


Eur J Med Chem 82: 281-92 (2014)


Article DOI: 10.1016/j.ejmech.2014.05.055
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(MOUSE)
BDBM50020599
PNG
(CHEMBL3290449)
Show SMILES Cc1ccc2c(c1)oc1c(nn(-c3ccc(Cl)cc3Cl)c21)C(=O)N[C@H]1CC2CC[C@]1(C)C2(C)C |r|
Show InChI InChI=1S/C27H27Cl2N3O2/c1-14-5-7-17-20(11-14)34-24-22(31-32(23(17)24)19-8-6-16(28)13-18(19)29)25(33)30-21-12-15-9-10-27(21,4)26(15,2)3/h5-8,11,13,15,21H,9-10,12H2,1-4H3,(H,30,33)/t15?,21-,27-/m0/s1
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3.5n/an/an/an/an/an/an/an/a



Universit£ di Sassari

Curated by ChEMBL


Assay Description
Displacement of [3H]-CP-55,940 from CB2 receptor in CD1 mouse spleen homogenate after 1 hr by liquid scintillation counting analysis


Eur J Med Chem 82: 281-92 (2014)


Article DOI: 10.1016/j.ejmech.2014.05.055
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(MOUSE)
BDBM50020598
PNG
(CHEMBL3290448)
Show SMILES C[C@@H]1C2CC(C[C@H]1NC(=O)c1nn(-c3ccc(Cl)cc3Cl)c3c1oc1cc(C)ccc31)C2(C)C |r|
Show InChI InChI=1S/C27H27Cl2N3O2/c1-13-5-7-17-22(9-13)34-25-23(31-32(24(17)25)21-8-6-16(28)12-19(21)29)26(33)30-20-11-15-10-18(14(20)2)27(15,3)4/h5-9,12,14-15,18,20H,10-11H2,1-4H3,(H,30,33)/t14-,15?,18?,20-/m1/s1
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3.70n/an/an/an/an/an/an/an/a



Universit£ di Sassari

Curated by ChEMBL


Assay Description
Displacement of [3H]-CP-55,940 from CB2 receptor in CD1 mouse spleen homogenate after 1 hr by liquid scintillation counting analysis


Eur J Med Chem 82: 281-92 (2014)


Article DOI: 10.1016/j.ejmech.2014.05.055
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(MOUSE)
BDBM50020591
PNG
(CHEMBL3290442)
Show SMILES Cc1ccc2c(c1)oc1c(nn(-c3ccc(Cl)cc3Cl)c21)C(=O)NN1CCCCC1
Show InChI InChI=1S/C22H20Cl2N4O2/c1-13-5-7-15-18(11-13)30-21-19(22(29)26-27-9-3-2-4-10-27)25-28(20(15)21)17-8-6-14(23)12-16(17)24/h5-8,11-12H,2-4,9-10H2,1H3,(H,26,29)
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13n/an/an/an/an/an/an/an/a



Universit£ di Sassari

Curated by ChEMBL


Assay Description
Displacement of [3H]-CP-55,940 from CB2 receptor in CD1 mouse spleen homogenate after 1 hr by liquid scintillation counting analysis


Eur J Med Chem 82: 281-92 (2014)


Article DOI: 10.1016/j.ejmech.2014.05.055
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(MOUSE)
BDBM50020594
PNG
(CHEMBL3290444)
Show SMILES Cc1ccc2c(c1)oc1c(nn(-c3ccc(Cl)cc3Cl)c21)C(=O)NC1CCCCC1
Show InChI InChI=1S/C23H21Cl2N3O2/c1-13-7-9-16-19(11-13)30-22-20(23(29)26-15-5-3-2-4-6-15)27-28(21(16)22)18-10-8-14(24)12-17(18)25/h7-12,15H,2-6H2,1H3,(H,26,29)
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16n/an/an/an/an/an/an/an/a



Universit£ di Sassari

Curated by ChEMBL


Assay Description
Displacement of [3H]-CP-55,940 from CB2 receptor in CD1 mouse spleen homogenate after 1 hr by liquid scintillation counting analysis


Eur J Med Chem 82: 281-92 (2014)


Article DOI: 10.1016/j.ejmech.2014.05.055
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(MOUSE)
BDBM50020595
PNG
(CHEMBL3290445)
Show SMILES Cc1ccc2c(c1)oc1c(nn(-c3ccc(Cl)cc3Cl)c21)C(=O)NC1C2CC3CC(C2)CC1C3 |TLB:23:24:26:30.28.29,THB:28:27:24:30.29.31,28:29:26.27.33:24,23:24:26.27.33:30.29.31,31:29:26:33.32.24,31:32:26:30.28.29,(4.16,-12.51,;5.31,-11.47,;4.98,-9.97,;6.13,-8.94,;7.6,-9.42,;7.91,-10.92,;6.77,-11.96,;9.44,-11.08,;10.07,-9.68,;11.41,-8.91,;11.09,-7.4,;9.55,-7.24,;8.78,-5.9,;9.55,-4.57,;8.78,-3.24,;7.24,-3.24,;6.47,-1.9,;6.47,-4.57,;7.24,-5.9,;6.47,-7.24,;8.93,-8.65,;12.81,-9.53,;12.97,-11.07,;14.06,-8.63,;15.47,-9.26,;15.48,-10.66,;14.35,-11.86,;15.76,-11.47,;17.09,-12,;18.04,-10.8,;16.72,-11.12,;18.06,-9.35,;16.73,-8.81,;15.75,-9.97,)|
Show InChI InChI=1S/C27H25Cl2N3O2/c1-13-2-4-19-22(6-13)34-26-24(31-32(25(19)26)21-5-3-18(28)12-20(21)29)27(33)30-23-16-8-14-7-15(10-16)11-17(23)9-14/h2-6,12,14-17,23H,7-11H2,1H3,(H,30,33)
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18n/an/an/an/an/an/an/an/a



Universit£ di Sassari

Curated by ChEMBL


Assay Description
Displacement of [3H]-CP-55,940 from CB2 receptor in CD1 mouse spleen homogenate after 1 hr by liquid scintillation counting analysis


Eur J Med Chem 82: 281-92 (2014)


Article DOI: 10.1016/j.ejmech.2014.05.055
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(MOUSE)
BDBM50020596
PNG
(CHEMBL3290446)
Show SMILES Cc1ccc2c(c1)oc1c(nn(-c3ccc(Cl)cc3Cl)c21)C(=O)NC12CC3CC(CC(C3)C1)C2 |THB:29:28:25:31.30.32,29:30:27.28.33:25,32:30:27:33.24.25,32:24:27:31.29.30|
Show InChI InChI=1S/C27H25Cl2N3O2/c1-14-2-4-19-22(6-14)34-25-23(31-32(24(19)25)21-5-3-18(28)10-20(21)29)26(33)30-27-11-15-7-16(12-27)9-17(8-15)13-27/h2-6,10,15-17H,7-9,11-13H2,1H3,(H,30,33)
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28n/an/an/an/an/an/an/an/a



Universit£ di Sassari

Curated by ChEMBL


Assay Description
Displacement of [3H]-CP-55,940 from CB2 receptor in CD1 mouse spleen homogenate after 1 hr by liquid scintillation counting analysis


Eur J Med Chem 82: 281-92 (2014)


Article DOI: 10.1016/j.ejmech.2014.05.055
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(MOUSE)
BDBM50020592
PNG
(CHEMBL3286437)
Show SMILES Cc1ccc2c(c1)oc1c(nn(-c3ccc(Cl)cc3Cl)c21)C(=O)NN1CCCC1
Show InChI InChI=1S/C21H18Cl2N4O2/c1-12-4-6-14-17(10-12)29-20-18(21(28)25-26-8-2-3-9-26)24-27(19(14)20)16-7-5-13(22)11-15(16)23/h4-7,10-11H,2-3,8-9H2,1H3,(H,25,28)
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30n/an/an/an/an/an/an/an/a



Universit£ di Sassari

Curated by ChEMBL


Assay Description
Displacement of [3H]-CP-55,940 from CB2 receptor in CD1 mouse spleen homogenate after 1 hr by liquid scintillation counting analysis


Eur J Med Chem 82: 281-92 (2014)


Article DOI: 10.1016/j.ejmech.2014.05.055
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Mus musculus (Mouse))
BDBM50020597
PNG
(CHEMBL3290447)
Show SMILES CC(C)[C@@H]1CC[C@@H](C)C[C@H]1NC(=O)c1nn(-c2ccc(Cl)cc2Cl)c2c3ccc(C)cc3oc12 |r|
Show InChI InChI=1S/C27H29Cl2N3O2/c1-14(2)18-8-5-15(3)11-21(18)30-27(33)24-26-25(19-9-6-16(4)12-23(19)34-26)32(31-24)22-10-7-17(28)13-20(22)29/h6-7,9-10,12-15,18,21H,5,8,11H2,1-4H3,(H,30,33)/t15-,18+,21-/m1/s1
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38n/an/an/an/an/an/an/an/a



Universit£ di Sassari

Curated by ChEMBL


Assay Description
Displacement of [3H]-CP-55,940 from CB1 receptor in CD1 mouse cerebellum-less brain homogenate after 1 hr by liquid scintillation counting analysis


Eur J Med Chem 82: 281-92 (2014)


Article DOI: 10.1016/j.ejmech.2014.05.055
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(MOUSE)
BDBM50020593
PNG
(CHEMBL3290443)
Show SMILES Cc1ccc2c(c1)oc1c(nn(-c3ccc(Cl)cc3Cl)c21)C(=O)NN1CCOCC1
Show InChI InChI=1S/C21H18Cl2N4O3/c1-12-2-4-14-17(10-12)30-20-18(21(28)25-26-6-8-29-9-7-26)24-27(19(14)20)16-5-3-13(22)11-15(16)23/h2-5,10-11H,6-9H2,1H3,(H,25,28)
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38n/an/an/an/an/an/an/an/a



Universit£ di Sassari

Curated by ChEMBL


Assay Description
Displacement of [3H]-CP-55,940 from CB2 receptor in CD1 mouse spleen homogenate after 1 hr by liquid scintillation counting analysis


Eur J Med Chem 82: 281-92 (2014)


Article DOI: 10.1016/j.ejmech.2014.05.055
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (Human))
BDBM50180022
PNG
(5-(4-chloro-3-methyl-phenyl)-1-(4-methyl-benzyl)-1...)
Show SMILES Cc1ccc(Cn2nc(cc2-c2ccc(Cl)c(C)c2)C(=O)NC2C3(C)CCC(C3)C2(C)C)cc1 |THB:21:22:26.25:28|
Show InChI InChI=1S/C29H34ClN3O/c1-18-6-8-20(9-7-18)17-33-25(21-10-11-23(30)19(2)14-21)15-24(32-33)26(34)31-27-28(3,4)22-12-13-29(27,5)16-22/h6-11,14-15,22,27H,12-13,16-17H2,1-5H3,(H,31,34)
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70n/an/an/an/an/an/an/an/a



Universit£ di Sassari

Curated by ChEMBL


Assay Description
Displacement of [3H]-CP-55,940 from CB1 receptor (unknown origin)


Eur J Med Chem 82: 281-92 (2014)


Article DOI: 10.1016/j.ejmech.2014.05.055
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Mus musculus (Mouse))
BDBM50020600
PNG
(CHEMBL3290450)
Show SMILES Cc1ccc2c(c1)oc1c(nn(-c3ccc(Cl)cc3Cl)c21)C(=O)N[C@H]1C2(C)CCC(C2)C1(C)C |r|
Show InChI InChI=1S/C27H27Cl2N3O2/c1-14-5-7-17-20(11-14)34-23-21(31-32(22(17)23)19-8-6-16(28)12-18(19)29)24(33)30-25-26(2,3)15-9-10-27(25,4)13-15/h5-8,11-12,15,25H,9-10,13H2,1-4H3,(H,30,33)/t15?,25-,27?/m1/s1
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257n/an/an/an/an/an/an/an/a



Universit£ di Sassari

Curated by ChEMBL


Assay Description
Displacement of [3H]-CP-55,940 from CB1 receptor in CD1 mouse cerebellum-less brain homogenate after 1 hr by liquid scintillation counting analysis


Eur J Med Chem 82: 281-92 (2014)


Article DOI: 10.1016/j.ejmech.2014.05.055
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Mus musculus (Mouse))
BDBM50020596
PNG
(CHEMBL3290446)
Show SMILES Cc1ccc2c(c1)oc1c(nn(-c3ccc(Cl)cc3Cl)c21)C(=O)NC12CC3CC(CC(C3)C1)C2 |THB:29:28:25:31.30.32,29:30:27.28.33:25,32:30:27:33.24.25,32:24:27:31.29.30|
Show InChI InChI=1S/C27H25Cl2N3O2/c1-14-2-4-19-22(6-14)34-25-23(31-32(24(19)25)21-5-3-18(28)10-20(21)29)26(33)30-27-11-15-7-16(12-27)9-17(8-15)13-27/h2-6,10,15-17H,7-9,11-13H2,1H3,(H,30,33)
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363n/an/an/an/an/an/an/an/a



Universit£ di Sassari

Curated by ChEMBL


Assay Description
Displacement of [3H]-CP-55,940 from CB1 receptor in CD1 mouse cerebellum-less brain homogenate after 1 hr by liquid scintillation counting analysis


Eur J Med Chem 82: 281-92 (2014)


Article DOI: 10.1016/j.ejmech.2014.05.055
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (Human))
BDBM50200169
PNG
(6-methyl-1-(2',4'-dichlorophenyl)-N-piperidin-1-yl...)
Show SMILES Cc1ccc-2c(Cc3c(nn(c-23)-c2ccc(Cl)cc2Cl)C(=O)NN2CCCCC2)c1
Show InChI InChI=1S/C23H22Cl2N4O/c1-14-5-7-17-15(11-14)12-18-21(23(30)27-28-9-3-2-4-10-28)26-29(22(17)18)20-8-6-16(24)13-19(20)25/h5-8,11,13H,2-4,9-10,12H2,1H3,(H,27,30)
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363n/an/an/an/an/an/an/an/a



Universit£ di Sassari

Curated by ChEMBL


Assay Description
Binding affinity to CB1 receptor (unknown origin)


Eur J Med Chem 82: 281-92 (2014)


Article DOI: 10.1016/j.ejmech.2014.05.055
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Mus musculus (Mouse))
BDBM50020599
PNG
(CHEMBL3290449)
Show SMILES Cc1ccc2c(c1)oc1c(nn(-c3ccc(Cl)cc3Cl)c21)C(=O)N[C@H]1CC2CC[C@]1(C)C2(C)C |r|
Show InChI InChI=1S/C27H27Cl2N3O2/c1-14-5-7-17-20(11-14)34-24-22(31-32(23(17)24)19-8-6-16(28)13-18(19)29)25(33)30-21-12-15-9-10-27(21,4)26(15,2)3/h5-8,11,13,15,21H,9-10,12H2,1-4H3,(H,30,33)/t15?,21-,27-/m0/s1
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469n/an/an/an/an/an/an/an/a



Universit£ di Sassari

Curated by ChEMBL


Assay Description
Displacement of [3H]-CP-55,940 from CB1 receptor in CD1 mouse cerebellum-less brain homogenate after 1 hr by liquid scintillation counting analysis


Eur J Med Chem 82: 281-92 (2014)


Article DOI: 10.1016/j.ejmech.2014.05.055
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Mus musculus (Mouse))
BDBM50020595
PNG
(CHEMBL3290445)
Show SMILES Cc1ccc2c(c1)oc1c(nn(-c3ccc(Cl)cc3Cl)c21)C(=O)NC1C2CC3CC(C2)CC1C3 |TLB:23:24:26:30.28.29,THB:28:27:24:30.29.31,28:29:26.27.33:24,23:24:26.27.33:30.29.31,31:29:26:33.32.24,31:32:26:30.28.29,(4.16,-12.51,;5.31,-11.47,;4.98,-9.97,;6.13,-8.94,;7.6,-9.42,;7.91,-10.92,;6.77,-11.96,;9.44,-11.08,;10.07,-9.68,;11.41,-8.91,;11.09,-7.4,;9.55,-7.24,;8.78,-5.9,;9.55,-4.57,;8.78,-3.24,;7.24,-3.24,;6.47,-1.9,;6.47,-4.57,;7.24,-5.9,;6.47,-7.24,;8.93,-8.65,;12.81,-9.53,;12.97,-11.07,;14.06,-8.63,;15.47,-9.26,;15.48,-10.66,;14.35,-11.86,;15.76,-11.47,;17.09,-12,;18.04,-10.8,;16.72,-11.12,;18.06,-9.35,;16.73,-8.81,;15.75,-9.97,)|
Show InChI InChI=1S/C27H25Cl2N3O2/c1-13-2-4-19-22(6-13)34-26-24(31-32(25(19)26)21-5-3-18(28)12-20(21)29)27(33)30-23-16-8-14-7-15(10-16)11-17(23)9-14/h2-6,12,14-17,23H,7-11H2,1H3,(H,30,33)
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537n/an/an/an/an/an/an/an/a



Universit£ di Sassari

Curated by ChEMBL


Assay Description
Displacement of [3H]-CP-55,940 from CB1 receptor in CD1 mouse cerebellum-less brain homogenate after 1 hr by liquid scintillation counting analysis


Eur J Med Chem 82: 281-92 (2014)


Article DOI: 10.1016/j.ejmech.2014.05.055
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Mus musculus (Mouse))
BDBM50020594
PNG
(CHEMBL3290444)
Show SMILES Cc1ccc2c(c1)oc1c(nn(-c3ccc(Cl)cc3Cl)c21)C(=O)NC1CCCCC1
Show InChI InChI=1S/C23H21Cl2N3O2/c1-13-7-9-16-19(11-13)30-22-20(23(29)26-15-5-3-2-4-6-15)27-28(21(16)22)18-10-8-14(24)12-17(18)25/h7-12,15H,2-6H2,1H3,(H,26,29)
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1.25E+3n/an/an/an/an/an/an/an/a



Universit£ di Sassari

Curated by ChEMBL


Assay Description
Displacement of [3H]-CP-55,940 from CB1 receptor in CD1 mouse cerebellum-less brain homogenate after 1 hr by liquid scintillation counting analysis


Eur J Med Chem 82: 281-92 (2014)


Article DOI: 10.1016/j.ejmech.2014.05.055
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Mus musculus (Mouse))
BDBM50020591
PNG
(CHEMBL3290442)
Show SMILES Cc1ccc2c(c1)oc1c(nn(-c3ccc(Cl)cc3Cl)c21)C(=O)NN1CCCCC1
Show InChI InChI=1S/C22H20Cl2N4O2/c1-13-5-7-15-18(11-13)30-21-19(22(29)26-27-9-3-2-4-10-27)25-28(20(15)21)17-8-6-14(23)12-16(17)24/h5-8,11-12H,2-4,9-10H2,1H3,(H,26,29)
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1.79E+3n/an/an/an/an/an/an/an/a



Universit£ di Sassari

Curated by ChEMBL


Assay Description
Displacement of [3H]-CP-55,940 from CB1 receptor in CD1 mouse cerebellum-less brain homogenate after 1 hr by liquid scintillation counting analysis


Eur J Med Chem 82: 281-92 (2014)


Article DOI: 10.1016/j.ejmech.2014.05.055
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Mus musculus (Mouse))
BDBM50020598
PNG
(CHEMBL3290448)
Show SMILES C[C@@H]1C2CC(C[C@H]1NC(=O)c1nn(-c3ccc(Cl)cc3Cl)c3c1oc1cc(C)ccc31)C2(C)C |r|
Show InChI InChI=1S/C27H27Cl2N3O2/c1-13-5-7-17-22(9-13)34-25-23(31-32(24(17)25)21-8-6-16(28)12-19(21)29)26(33)30-20-11-15-10-18(14(20)2)27(15,3)4/h5-9,12,14-15,18,20H,10-11H2,1-4H3,(H,30,33)/t14-,15?,18?,20-/m1/s1
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2.40E+3n/an/an/an/an/an/an/an/a



Universit£ di Sassari

Curated by ChEMBL


Assay Description
Displacement of [3H]-CP-55,940 from CB1 receptor in CD1 mouse cerebellum-less brain homogenate after 1 hr by liquid scintillation counting analysis


Eur J Med Chem 82: 281-92 (2014)


Article DOI: 10.1016/j.ejmech.2014.05.055
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Mus musculus (Mouse))
BDBM50020592
PNG
(CHEMBL3286437)
Show SMILES Cc1ccc2c(c1)oc1c(nn(-c3ccc(Cl)cc3Cl)c21)C(=O)NN1CCCC1
Show InChI InChI=1S/C21H18Cl2N4O2/c1-12-4-6-14-17(10-12)29-20-18(21(28)25-26-8-2-3-9-26)24-27(19(14)20)16-7-5-13(22)11-15(16)23/h4-7,10-11H,2-3,8-9H2,1H3,(H,25,28)
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2.72E+3n/an/an/an/an/an/an/an/a



Universit£ di Sassari

Curated by ChEMBL


Assay Description
Displacement of [3H]-CP-55,940 from CB1 receptor in CD1 mouse cerebellum-less brain homogenate after 1 hr by liquid scintillation counting analysis


Eur J Med Chem 82: 281-92 (2014)


Article DOI: 10.1016/j.ejmech.2014.05.055
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Mus musculus (Mouse))
BDBM50020593
PNG
(CHEMBL3290443)
Show SMILES Cc1ccc2c(c1)oc1c(nn(-c3ccc(Cl)cc3Cl)c21)C(=O)NN1CCOCC1
Show InChI InChI=1S/C21H18Cl2N4O3/c1-12-2-4-14-17(10-12)30-20-18(21(28)25-26-6-8-29-9-7-26)24-27(19(14)20)16-5-3-13(22)11-15(16)23/h2-5,10-11H,6-9H2,1H3,(H,25,28)
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4.06E+3n/an/an/an/an/an/an/an/a



Universit£ di Sassari

Curated by ChEMBL


Assay Description
Displacement of [3H]-CP-55,940 from CB1 receptor in CD1 mouse cerebellum-less brain homogenate after 1 hr by liquid scintillation counting analysis


Eur J Med Chem 82: 281-92 (2014)


Article DOI: 10.1016/j.ejmech.2014.05.055
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%