BindingDB logo
myBDB logout

56 articles for thisTarget

The following articles (labelled with PubMed ID or TBD) are for your review
PMIDDataArticle TitleOrganization
27876250 60 Structure-anticonvulsant activity studies in the group of (E)-N-cinnamoyl aminoalkanols derivatives monosubstituted in phenyl ring with 4-Cl, 4-CHEBI Jagiellonian University Medical College
26988801 55 Design, physico-chemical properties and biological evaluation of some new N-[(phenoxy)alkyl]- and N-{2-[2-(phenoxy)ethoxy]ethyl}aminoalkanols as anticonvulsant agents.EBI Jagiellonian University Medical College
26390077 42 Tactical Approaches to Interconverting GPCR Agonists and Antagonists.EBI University of Minnesota
26810314 12 Structural determinants of subtype selectivity and functional activity of angiotensin II receptors.EBI Uppsala University
25699147 6 Interconversion of Functional Activity by Minor Structural Alterations in Nonpeptide AT2 Receptor Ligands.EBI Uppsala University
25313325 8 Saralasin and Sarile Are AT2 Receptor Agonists.EBI Universit£
21413808 170 Synopsis of some recent tactical application of bioisosteres in drug design.EBI Bristol-Myers Squibb Pharmaceutical Research and Development
20875743 90 Discovery of {1-[4-(2-{hexahydropyrrolo[3,4-c]pyrrol-2(1H)-yl}-1H-benzimidazol-1-yl)piperidin-1-yl]cyclooctyl}methanol, systemically potent novel non-peptide agonist of nociceptin/orphanin FQ receptor as analgesic for the treatment of neuropathic pain: design, synthesis, and structure-activity relaEBI Pfizer
20493713 30 Selective angiotensin II AT(2) receptor agonists with reduced CYP 450 inhibition.EBI Uppsala University
17358051 13 Synthesis of a new class of druglike angiotensin II C-terminal mimics with affinity for the AT2 receptor.EBI Uppsala University
17004728 4 Design, synthesis, and incorporation of a beta-turn mimetic in angiotensin II forming novel pseudopeptides with affinity for AT1 and AT2 receptors.EBI Uppsala University
16220978 14 Angiotensin II pseudopeptides containing 1,3,5-trisubstituted benzene scaffolds with high AT2 receptor affinity.EBI Uppsala University
16220969 219 Designed multiple ligands. An emerging drug discovery paradigm.EBI Organon Laboratories
15943474 10 New selective AT2 receptor ligands encompassing a gamma-turn mimetic replacing the amino acid residues 4-5 of angiotensin II act as agonists.EBI Uppsala University
15537355 4 AT2-selective angiotensin II analogues containing tyrosine-functionalized 5,5-bicyclic thiazabicycloalkane dipeptide mimetics.EBI Uppsala University
15537354 14 Design, synthesis, and biological evaluation of the first selective nonpeptide AT2 receptor agonist.EBI Uppsala University
7241506 40 New analgesic drugs derived from phencyclidine.EBI TBA
14761188 8 A selective AT2 receptor ligand with a gamma-turn-like mimetic replacing the amino acid residues 4-5 of angiotensin II.EBI Uppsala University
8576904 78 Nonpeptide angiotensin II receptor antagonists: the next generation in antihypertensive therapy.EBI Dupont Pharmaceuticals
 32 L-161,638: A potent AT2selective quinazolinone angiotensin II binding inhibitorEBI TBA
 4 The syntheses and binding affinities of tools for the study of angiotensin AT2 receptorsEBI TBA
22309912 28 Design, synthesis and biological evaluation of 6-substituted aminocarbonyl benzimidazole derivatives as nonpeptidic angiotensin II AT1 receptor antagonists.EBI Beijing Institute of Technology
21557540 39 Discovery of a series of imidazo[4,5-b]pyridines with dual activity at angiotensin II type 1 receptor and peroxisome proliferator-activated receptor-¿.EBI Pfizer
21071232 78 Angiotensin II receptor type 1 (AT1) selective nonpeptidic antagonists--a perspective.EBI The M. S. University of Baroda
 42 Balanced AT1 and AT2 angiotensin II antagonists. II. Potent 5 α-hydroxyacid imidazolyl biphenyl sulfonylureasEBI TBA
 17 AT1 selective angiotensin II antagonists with phenoxyphenylacetic acid as a biphenyl replacement part IEBI TBA
 56 Potent triazolinone-based angiotensin II receptor antagonists with equivalent affinity for both the AT1 and AT2 subtypesEBI TBA
 134 Development of angiotensin II antagonists with equipotent affinity for human AT1 and AT2 receptor subtypes.EBI TBA
 122 Balanced angiotensin II receptor antagonists. III. The effects of substitution at the imidazole 5-position.EBI TBA
 68 Balanced angiotensin II receptor antagonists. II.1,2 4-aminomethyl- and acylaminomethylimidazolesEBI TBA
 19 Imidazolinones as nonpeptide angiotensin II receptor antagonistsEBI TBA
 21 Tetrahydroisoquinoline derivatives with AT2-specific angiotensin II reception binding inhibitory activityEBI TBA
 1 4,5,6,7-Tetrahdryo-8-oxo-cycloheptimidazoles: a new class of potent non-peptide angiiotensin II receptor antagonistsEBI TBA
19447613 9 Nocathiacin analogs: Synthesis and antibacterial activity of novel water-soluble amides.EBI Merck Research Laboratories
17125268 44 Selective angiotensin II AT2 receptor agonists: arylbenzylimidazole structure-activity relationships.EBI Uppsala University
14998339 22 First reported nonpeptide AT1 receptor agonist (L-162,313) acts as an AT2 receptor agonist in vivo.EBI Uppsala University
32030982 14 The Other Angiotensin II Receptor: ATEBI Centre Hospitalier Universitaire Vaudois (Chuv) and University of Lausanne (Unil
30655952 89 Discovery of TD-0212, an Orally Active Dual Pharmacology ATEBI Theravance Biopharma Us
8515427 43 Multiple binding modes for the receptor-bound conformations of cyclic AII agonists.EBI Washington University
8201597 10 Non-peptide angiotensin II receptor antagonists: synthesis and biological activity of a series of novel 4,5-dihydro-4-oxo-3H-imidazo[4,5-c]pyridine derivatives.EBI E. Merck
24200932 2 Design, synthesis, and biological evaluation of 1,2,4-triazole bearing 5-substituted biphenyl-2-sulfonamide derivatives as potential antihypertensive candidates.EBI China Pharmaceutical University
24007859 33 Nonpeptidic angiotensin II AT? receptor antagonists derived from 6-substituted aminocarbonyl and acylamino benzimidazoles.EBI Beijing Institute of Technology
7562906 3 Derivatives of 5-[[1-(4'-carboxybenzyl)imidazolyl]methylidene]hydantoins as orally active angiotensin II receptor antagonists.EBI Warner-Lambert
7562905 258 Potent and orally active angiotensin II receptor antagonists with equal affinity for human AT1 and AT2 subtypes.EBI Merck Research Laboratories
29969256 21 Fibrogenic Disorders in Human Diseases: From Inflammation to Organ Dysfunction.EBI Universitaire Vaudois
9225286 13 SB 242084, a selective and brain penetrant 5-HT2C receptor antagonist.BDB Smithkline Beecham Pharmaceuticals
18579376 23 Novel alkoxybenzamide inhibitors of poly(ADP-ribose) polymerase.BDB Kudos Pharmaceuticals
19138518 51 Investigation on the role of the tetrazole in the binding of thiotetrazolylacetanilides with HIV-1 wild type and K103N/Y181C double mutant reverse transcriptases.BDB Boehringer Ingelheim (Canada)
14695825 67 Potent inhibitors of the Plasmodium falciparum enzymes plasmepsin I and II devoid of cathepsin D inhibitory activity.BDB Uppsala University
12139449 114 Probing the ATP ribose-binding domain of cyclin-dependent kinases 1 and 2 with O(6)-substituted guanine derivatives.BDB University of Newcastle