85 articles for thisTarget

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The following articles (labelled with PubMed ID or TBD) are for your review

PMID	Data	Article Title	Organization
27050842	39	Potent and Selective Human Neuronal Nitric Oxide Synthase Inhibition by Optimization of the 2-Aminopyridine-Based Scaffold with a Pyridine Linker.	Northwestern University
26120733	36	2-Aminopyridines with a Truncated Side Chain To Improve Human Neuronal Nitric Oxide Synthase Inhibitory Potency and Selectivity.	Northwestern University
25602734	4	Cell-permeable inhibitors of neuronal nitric oxide synthase open new prospects for the treatment of neurological disorders.	Vibrant Pharma
25489882	63	Novel 2,4-disubstituted pyrimidines as potent, selective, and cell-permeable inhibitors of neuronal nitric oxide synthase.	Northwestern University
25522110	21	Structure-based design of bacterial nitric oxide synthase inhibitors.	University of California
25149509	30	Combination of chiral linkers with thiophenecarboximidamide heads to improve the selectivity of inhibitors of neuronal nitric oxide synthase.	Northwestern University
24758147	31	Nitric oxide synthase inhibitors that interact with both heme propionate and tetrahydrobiopterin show high isoform selectivity.	Northwestern University
24472039	39	Simplified 2-aminoquinoline-based scaffold for potent and selective neuronal nitric oxide synthase inhibition.	Northwestern University
24447275	33	Potent and selective double-headed thiophene-2-carboximidamide inhibitors of neuronal nitric oxide synthase for the treatment of melanoma.	Northwestern University
24660051	24	An Accessible Chiral Linker to Enhance Potency and Selectivity of Neuronal Nitric Oxide Synthase Inhibitors.	Northwestern University
23993333	27	Chiral linkers to improve selectivity of double-headed neuronal nitric oxide synthase inhibitors.	Northwestern University
23867386	31	In search of potent and selective inhibitors of neuronal nitric oxide synthase with more simple structures.	Northwestern University
23458846	16	Target- and mechanism-based therapeutics for neurodegenerative diseases: strength in numbers.	Northwestern University
23352768	21	Cyclopropyl- and methyl-containing inhibitors of neuronal nitric oxide synthase.	University of California
23451760	18	Structure-guided design of selective inhibitors of neuronal nitric oxide synthase.	Northwestern University
22831803	9	New hypotheses for the binding mode of 4- and 7-substituted indazoles in the active site of neuronal nitric oxide synthase.	Universit£
22370270	30	Novel, druglike 1,7-disubstituted 2,3,4,5-tetrahydro-1H-benzo[b]azepine-based selective inhibitors of human neuronal nitric oxide synthase (nNOS).	Neuraxon
19144449	22	Synthesis and evaluation of pyrido[1,2-a]pyrimidines as inhibitors of nitric oxide synthases.	Christian-Albrechts-University of Kiel
17317165	77	Novel 2-aminobenzothiazoles as selective neuronal nitric oxide synthase inhibitors.	Neuraxon
16821802	30	Imidazole-dioxolane compounds as isozyme-selective heme oxygenase inhibitors.	Queen'S University
14736250	50	Potent and selective conformationally restricted neuronal nitric oxide synthase inhibitors.	Northwestern University
12699384	69	Aromatic reduced amide bond peptidomimetics as selective inhibitors of neuronal nitric oxide synthase.	Northwestern University
11472219	27	Reduced amide bond peptidomimetics. (4S)-N-(4-amino-5-[aminoakyl]aminopentyl)-N'-nitroguanidines, potent and highly selective inhibitors of neuronal nitric oxide synthase.	Northwestern University
9397167	15	Potent and selective inhibition of neuronal nitric oxide synthase by N omega-propyl-L-arginine.	Northwestern University
12482425	20	Novel inhibitors of neuronal nitric oxide synthase with potent antioxidant properties.	Institut Henri Beaufour
11133088	46	1H-pyrazole-1-carboxamidines: new inhibitors of nitric oxide synthase.	Northwestern University
22370337	30	Intramolecular hydrogen bonding: a potential strategy for more bioavailable inhibitors of neuronal nitric oxide synthase.	Northwestern University
22318159	36	3,5-Disubstituted indole derivatives as selective human neuronal nitric oxide synthase (nNOS) inhibitors.	Neuraxon
22175766	45	Discovery of cis-N-(1-(4-(methylamino)cyclohexyl)indolin-6-yl)thiophene-2-carboximidamide: a 1,6-disubstituted indoline derivative as a highly selective inhibitor of human neuronal nitric oxide synthase (nNOS) without any cardiovascular liabilities.	Neuraxon
22280820	53	Novel inhibitors of nitric oxide synthase with antioxidant properties.	Universit£
21699209	75	Design, synthesis, and biological evaluation of 3,4-dihydroquinolin-2(1H)-one and 1,2,3,4-tetrahydroquinoline-based selective human neuronal nitric oxide synthase (nNOS) inhibitors.	Neuraxon
21809851	21	Improved synthesis of chiral pyrrolidine inhibitors and their binding properties to neuronal nitric oxide synthase.	Northwestern University
21665485	4	Synthesis and evaluation of fluorescent heterocyclic aminoadamantanes as multifunctional neuroprotective agents.	North-West University
21410186	43	Symmetric double-headed aminopyridines, a novel strategy for potent and membrane-permeable inhibitors of neuronal nitric oxide synthase.	Northwestern University
21334118	1	Synthesis and biological evaluation of indazole derivatives.	Uned
20958055	133	Exploration of the active site of neuronal nitric oxide synthase by the design and synthesis of pyrrolidinomethyl 2-aminopyridine derivatives.	Northwestern University
20933416	33	N-Substituted acetamidines and 2-methylimidazole derivatives as selective inhibitors of neuronal nitric oxide synthase.	Università
20833542	16	Peripheral but crucial: a hydrophobic pocket (Tyr(706), Leu(337), and Met(336)) for potent and selective inhibition of neuronal nitric oxide synthase.	Northwestern University
20673724	33	Structure-based design, synthesis, and biological evaluation of lipophilic-tailed monocationic inhibitors of neuronal nitric oxide synthase.	Northwestern University
20441173	19	2-aminoimidazole amino acids as inhibitors of the binuclear manganese metalloenzyme human arginase I.	University of Pennsylvania
19963381	18	Potent and selective neuronal nitric oxide synthase inhibitors with improved cellular permeability.	Northwestern University
19505081	3	Eusynstyelamides A, B, and C, nNOS inhibitors, from the ascidian Eusynstyela latericius.	Institute of Marine Science
	16	Synthesis of phosphorus-containing amino acid analogs as inhibitors of nitric oxide synthase	TBA
	10	1,2-diaminobenzimidazoles : Selective inhibitors of nitric oxide synthase derived from aminoguanidine	TBA
19537690	24	L337H mutant of rat neuronal nitric oxide synthase resembles human neuronal nitric oxide synthase toward inhibitors.	Northwestern University
19268602	18	Analogues of 2-aminopyridine-based selective inhibitors of neuronal nitric oxide synthase with increased bioavailability.	Northwestern University
19125620	96	Discovery of highly potent and selective inhibitors of neuronal nitric oxide synthase by fragment hopping.	Northwestern University
18502134	55	Inhibitory effects of a series of 7-substituted-indazoles toward nitric oxide synthases: particular potency of 1H-indazole-7-carbonitrile.	Université
17395463	14	4-substituted indazoles as new inhibitors of neuronal nitric oxide synthase.	Upres-Ea 3915
17239601	33	Selective L-nitroargininylaminopyrrolidine and L-nitroargininylaminopiperidine neuronal nitric oxide synthase inhibitors.	Northwestern University
17034131	19	Conformationally restricted dipeptide amides as potent and selective neuronal nitric oxide synthase inhibitors.	Northwestern University
14998342	73	Structure-activity relationships of potent, selective inhibitors of neuronal nitric oxide synthase based on the 6-phenyl-2-aminopyridine structure.	Pfizer
11784131	2	Inhibition of nNOS activity in rat brain by synthetic kynurenines: structure-activity dependence.	Universidad De Granada
11354365	11	Inhibition of neuronal nitric oxide synthase by 7-methoxyindazole and related substituted indazoles.	Université
11327581	44	Thienopyridines: nitric oxide synthase inhibitors with potent in vivo activity.	Astrazeneca R&D Charnwood
11327580	73	3,4-Dihydro-1-isoquinolinamines: a novel class of nitric oxide synthase inhibitors with a range of isoform selectivity and potency.	Astrazeneca R&D Charnwood
11133090	2	Evaluation of new L-thiocitrulline derivatives as inhibitors of nitric oxide synthase.	Wake Forest University
10571154	8	Guanidine-substituted imidazoles as inhibitors of nitric oxide synthase.	Wake Forest University Winston-Salem
30802056	63	Optimization of Blood-Brain Barrier Permeability with Potent and Selective Human Neuronal Nitric Oxide Synthase Inhibitors Having a 2-Aminopyridine Scaffold.	Northwestern University
10498210	27	A new class of selective and potent inhibitors of neuronal nitric oxide synthase.	Pfizer
32302123	114	First Contact: 7-Phenyl-2-Aminoquinolines, Potent and Selective Neuronal Nitric Oxide Synthase Inhibitors That Target an Isoform-Specific Aspartate.	Northwestern University
9651169	49	Nitroaromatic amino acids as inhibitors of neuronal nitric oxide synthase.	Abbott Laboratories
26469213	58	Phenyl Ether- and Aniline-Containing 2-Aminoquinolines as Potent and Selective Inhibitors of Neuronal Nitric Oxide Synthase.	Northwestern University
29689474	32	Discovery of N-{3-[(ethanimidoylamino)methyl]benzyl}-l-prolinamide dihydrochloride: A new potent and selective inhibitor of the inducible nitric oxide synthase as a promising agent for the therapy of malignant glioma.	University of Chieti "G. D'Annunzio
28422508	78	Nitrile in the Hole: Discovery of a Small Auxiliary Pocket in Neuronal Nitric Oxide Synthase Leading to the Development of Potent and Selective 2-Aminoquinoline Inhibitors.	Northwestern University
28776992	110	Hydrophilic, Potent, and Selective 7-Substituted 2-Aminoquinolines as Improved Human Neuronal Nitric Oxide Synthase Inhibitors.	Northwestern University
29091437	50	Improvement of Cell Permeability of Human Neuronal Nitric Oxide Synthase Inhibitors Using Potent and Selective 2-Aminopyridine-Based Scaffolds with a Fluorobenzene Linker.	Northwestern University
22380775	28	2-(2-indolyl-)-4(3H)-quinazolines derivates as new inhibitors of AChE: design, synthesis, biological evaluation and molecular modelling.	Sun Yat-Sen University
8863814	21	Identification and characterization of novel somatostatin antagonists.	Cyenamid Agricultural Research Center
7891350	9	Pharmacologic characterization of CI-996, a new angiotensin receptor antagonist.	Parke-Davis Pharmaceutical Research
17524982	10	Alkyl-CoA disulfides as inhibitors and mechanistic probes for FabH enzymes.	Portland State University
17379147	5	Covalent reactions of wortmannin under physiological conditions.	Massachusetts General Hospital
15027867	10	Inactivation of purified human recombinant monoamine oxidases A and B by rasagiline and its analogues.	Emory University