33 articles for thisTarget

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The following articles (labelled with PubMed ID or TBD) are for your review

PMID	Data	Article Title	Organization
28152426	3	Design and synthesis of a new series of 3,5-disubstituted isoxazoles active against Trypanosoma cruzi and Leishmania amazonensis.	Federal University of Santa Catarina
26200936	39	Applications of Fluorine in Medicinal Chemistry.	Bristol-Myers Squibb Research and Development
25661449	8	Dibenzosuberyl substituted polyamines and analogs of clomipramine as effective inhibitors of trypanothione reductase; molecular docking, and assessment of trypanocidal activities.	Canisius College
24321832	38	Synthesis and evaluation of the antiparasitic activity of bis-(arylmethylidene) cycloalkanones.	Universidade Federal De Minas Gerais
16033259	7	Inhibitors of Trypanosoma cruzi trypanothione reductase revealed by virtual screening and parallel synthesis.	Universit£T Heidelberg
10956223	41	Use of an additional hydrophobic binding site, the Z site, in the rational drug design of a new class of stronger trypanothione reductase inhibitor, quaternary alkylammonium phenothiazines.	University of Manchester
11055357	10	Optimising inhibitors of trypanothione reductase using solid-phase chemistry.	University of Southamton
21851087	88	Dihydroquinazolines as a novel class of Trypanosoma brucei trypanothione reductase inhibitors: discovery, synthesis, and characterization of their binding mode by protein crystallography.	University of Dundee
21807515	9	A fast virtual screening approach to identify structurally diverse inhibitors of trypanothione reductase.	Universit£
19364854	24	Trypanothione reductase high-throughput screening campaign identifies novel classes of inhibitors with antiparasitic activity.	Monash University (Parkville Campus)
20185305	1	Discovery of novel and potent benzhydryl-tropane trypanocides highly selective for Trypanosoma cruzi.	Institute of Medical Research
19606868	2	Neglected tropical diseases: multi-target-directed ligands in the search for novel lead candidates against Trypanosoma and Leishmania.	University of Bologna
19414258	8	Privileged structure-guided synthesis of quinazoline derivatives as inhibitors of trypanothione reductase.	Alma Mater Studiorum-Bologna University
	8	Novel polyamine derivatives as potent competitive inhibitors of Trypanosoma cruzi trypanothione reductase	TBA
	3	Synthesis of non reducible inhibitors for trypanothione reductase from Trypanosoma cruzi.	TBA
18558492	16	The use of natural product scaffolds as leads in the search for trypanothione reductase inhibitors.	Pontificia Universidad Catolica Del Peru
16616495	28	Novel alkylpolyaminoguanidines and alkylpolyaminobiguanides with potent antitrypanosomal activity.	Wayne State University
16335933	23	Antitrypanosomal, antileishmanial, and antimalarial activities of quaternary arylalkylammonium 2-amino-4-chlorophenyl phenyl sulfides, a new class of trypanothione reductase inhibitor, and of N-acyl derivatives of 2-amino-4-chlorophenyl phenyl sulfide.	University of Manchester
16279799	5	Irreversible inactivation of trypanothione reductase by unsaturated Mannich bases: a divinyl ketone as key intermediate.	Biochemie-Zentrum Der UniversitäT Heidelberg
12443785	4	Antitrypanosomal activities and cytotoxicity of 5-nitro-2-furancarbohydrazides.	Université
11551771	16	Antiprotozoal and cytotoxicity evaluation of sulfonamide and urea analogues of quinacrine.	University of Cape Town
11206471	11	Polyamines with N-(3-phenylpropyl) substituents are effective competitive inhibitors of trypanothione reductase and trypanocidal agents.	Indiana State University
11170645	77	2- and 3-substituted 1,4-naphthoquinone derivatives as subversive substrates of trypanothione reductase and lipoamide dehydrogenase from Trypanosoma cruzi: synthesis and correlation between redox cycling activities and in vitro cytotoxicity.	Umr 8525 Cnrs - Université
10762041	6	Parallel synthesis of a library of 1,4-naphthoquinones and automated screening of potential inhibitors of trypanothione reductase from Trypanosoma cruzi.	Université
10639286	14	Inhibition of Trypanosoma cruzi trypanothione reductase by acridines: kinetic studies and structure-activity relationships.	Heidelberg University
29400967	136	Fluorine and Fluorinated Motifs in the Design and Application of Bioisosteres for Drug Design.	Bristol-Myers Squibb
9871730	20	Structure-activity relationships in 2-aminodiphenylsulfides against trypanothione reductase from Trypanosoma cruzi.	Ura Cnrs 1309
9457238	59	Phenothiazine inhibitors of trypanothione reductase as potential antitrypanosomal and antileishmanial drugs.	University of Manchester
28926763	5	Synthesis and 2D-QSAR studies of neolignan-based diaryl-tetrahydrofuran and -furan analogues with remarkable activity against Trypanosoma cruzi and assessment of the trypanothione reductase activity.	University of S£O Paulo
29031061	5	Crassiflorone derivatives that inhibit Trypanosoma brucei glyceraldehyde-3-phosphate dehydrogenase (TbGAPDH) and Trypanosoma cruzi trypanothione reductase (TcTR) and display trypanocidal activity.	University of Bologna
28698054	9	Bistacrines as potential antitrypanosomal agents.	Julius-Maximilians-University of W£Rzburg
27810595	14	Rational design of nitrofuran derivatives: Synthesis and valuation as inhibitors of Trypanosoma cruzi trypanothione reductase.	Universidad Nacional Del Litoral
19101978	6	The molecular basis of inhibition of Golgi alpha-mannosidase II by mannostatin A.	University of Toronto