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70 articles for thisTarget


The following articles (labelled with PubMed ID or TBD) are for your review
PMIDDataArticle TitleOrganization
27504669 39 Hernandezine, a Bisbenzylisoquinoline Alkaloid with Selective Inhibitory Activity against Multidrug-Resistance-Linked ATP-Binding Cassette Drug Transporter ABCB1.EBI Chang Gung Memorial Hospital
26943020 65 Pyrrolopyrimidine Derivatives as Novel Inhibitors of Multidrug Resistance-Associated Protein 1 (MRP1, ABCC1).EBI University of Bonn
26774038 67 Flavonoid derivatives as selective ABCC1 modulators: Synthesis and functional characterization.EBI University of Regensburg
25985195 94 Potent and Nontoxic Chemosensitizer of P-Glycoprotein-Mediated Multidrug Resistance in Cancer: Synthesis and Evaluation of Methylated Epigallocatechin, Gallocatechin, and Dihydromyricetin Derivatives.EBI The Hong Kong Polytechnic University
21511945 7 Cannabinoid type 1 receptor antagonists modulate transport activity of multidrug resistance-associated proteins MRP1, MRP2, MRP3, and MRP4.EBI Radboud University Nijmegen Medical Centre
25093931 44 Trimethoxybenzanilide-based P-glycoprotein modulators: an interesting case of lipophilicity tuning by intramolecular hydrogen bonding.EBI Universit£
25379609 24 SAR studies on tetrahydroisoquinoline derivatives: the role of flexibility and bioisosterism to raise potency and selectivity toward P-glycoprotein.EBI Universit£
25311564 30 Thieno[2,3-b]pyridines--a new class of multidrug resistance (MDR) modulators.EBI Institute of Organic Synthesis
24184213 71 Investigation of quinazolines as inhibitors of breast cancer resistance protein (ABCG2).EBI University of Bonn
23851114 73 Synthesis and biological evaluation of flavones and benzoflavones as inhibitors of BCRP/ABCG2.EBI University of Bonn
23726026 12 Activity-lipophilicity relationship studies on P-gp ligands designed as simplified tariquidar bulky fragments.EBI Universit£
23374872 27 Potent and selective tariquidar bioisosters as potential PET radiotracers for imaging P-gp.EBI Universit£
23347803 29 Naphthalenyl derivatives for hitting P-gp/MRP1/BCRP transporters.EBI Universit£
9188796 1 Anthracyclines modulate multidrug resistance protein (MRP) mediated organic anion transport.EBI Academic Hospital Vrije Universiteit
8640791 1 Transport of glutathione, glucuronate, and sulfate conjugates by the MRP gene-encoded conjugate export pump.EBI Deutsches Krebsforschungszentrum
9355767 6 ATP-dependent transport of bilirubin glucuronides by the multidrug resistance protein MRP1 and its hepatocyte canalicular isoform MRP2.EBI Deutsches Krebsforschungszentrum
11306701 5 Modulation of multidrug resistance protein 1 (MRP1/ABCC1) transport and atpase activities by interaction with dietary flavonoids.EBI Queen'S University
8621644 9 ATP-dependent 17 beta-estradiol 17-(beta-D-glucuronide) transport by multidrug resistance protein (MRP). Inhibition by cholestatic steroids.EBI Queen'S University
16434618 3 Multidrug resistance protein 1 (MRP1, ABCC1) mediates resistance to mitoxantrone via glutathione-dependent drug efflux.EBI Wake Forest University School of Medicine
16384552 4 Interaction of ivermectin with multidrug resistance proteins (MRP1, 2 and 3).EBI Laboratoire De Pharmacologie-Toxicologie Inra
10612603 1 Reversal of resistance in multidrug resistance protein (MRP1)-overexpressing cells by LY329146.EBI Eli Lilly
23017888 26 4-Substituted-2-phenylquinazolines as inhibitors of BCRP.EBI University of Bonn
22366653 3 Discovery of GS-9451: an acid inhibitor of the hepatitis C virus NS3/4A protease.EBI Gilead Sciences
22165858 8 Substituted chromones as highly potent nontoxic inhibitors, specific for the breast cancer resistance protein.EBI Cnrs/Universit£
18707884 12 A 4-aminobenzoic acid derivative as novel lead for selective inhibitors of multidrug resistance-associated proteins.EBI University of Bonn
22112208 98 Potent galloyl-based selective modulators targeting multidrug resistance associated protein 1 and P-glycoprotein.EBI Universit£
21530277 3 Molecular docking studies and in vitro screening of new dihydropyridine derivatives as human MRP1 inhibitors.EBI Kakatiya University
21189339 5 Interaction potential of etravirine with drug transporters assessed in vitro.EBI University Hospital Heidelberg
21354800 77 Structure-activity relationships of flavonoids as inhibitors of breast cancer resistance protein (BCRP).EBI University of Bonn
20684594 71 Phenylsulfonylfuroxans as modulators of multidrug-resistance-associated protein-1 and P-glycoprotein.EBI Universita Degli Studi Di Torino
19932960 47 Novel lead for potent inhibitors of breast cancer resistance protein (BCRP).EBI University of Bonn
19725578 20 Modulation of multidrug resistance protein 1 (MRP1/ABCC1)-mediated multidrug resistance by bivalent apigenin homodimers and their derivatives.EBI The Hong Kong Polytechnic University
19580319 40 Aromatic 2-(thio)ureidocarboxylic acids as a new family of modulators of multidrug resistance-associated protein 1: synthesis, biological evaluation, and structure-activity relationships.EBI University of Bonn
17646169 2 (R)- and (S)-verapamil differentially modulate the multidrug-resistant protein MRP1.EBI Institut De Biologie Et Chimie Des ProtéInes
16202586 7 Cyclohexyl-linked tricyclic isoxazoles are potent and selective modulators of the multidrug resistance protein (MRP1).EBI Eli Lilly
16168641 35 Topological model for the prediction of MRP1 inhibitory activity of pyrrolopyrimidines and templates derived from pyrrolopyrimidine.EBI M.D. University
14998324 190 Design and synthesis of new templates derived from pyrrolopyrimidine as selective multidrug-resistance-associated protein inhibitors in multidrug resistance.EBI Xenova
14998323 79 Studies on pyrrolopyrimidines as selective inhibitors of multidrug-resistance-associated protein in multidrug resistance.EBI Xenova
11844674 59 Studies on quinazolinones as dual inhibitors of Pgp and MRP1 in multidrug resistance.EBI Xenova
32347726 41 Licochalcone A Selectively Resensitizes ABCG2-Overexpressing Multidrug-Resistant Cancer Cells to Chemotherapeutic Drugs.EBI Taipei Chang Gung Memorial Hospital
27148793 112 Synthesis and Biological Evaluation of 4-Anilino-quinazolines and -quinolines as Inhibitors of Breast Cancer Resistance Protein (ABCG2).EBI University of Bonn
30594677 62 Novel chalcone and flavone derivatives as selective and dual inhibitors of the transport proteins ABCB1 and ABCG2.EBI Rheinische Friedrich-Wilhelms-University of Bonn
30584838 44 Design, Biological Evaluation, and Molecular Modeling of Tetrahydroisoquinoline Derivatives: Discovery of A Potent P-Glycoprotein Ligand Overcoming Multidrug Resistance in Cancer Stem Cells.EBI Universit£
30947123 26 Modulation of the spacer in N,N-bis(alkanol)amine aryl ester heterodimers led to the discovery of a series of highly potent P-glycoprotein-based multidrug resistance (MDR) modulators.EBI University of Florence
31494468 61 Design, synthesis and biological evaluation of stereo- and regioisomers of amino aryl esters as multidrug resistance (MDR) reversers.EBI University of Florence
30925062 34 Identification of Thienopyrimidine Scaffold as an Inhibitor of the ABC Transport Protein ABCC1 (MRP1) and Related Transporters Using a Combined Virtual Screening Approach.EBI Rheinische Friedrich-Wilhelms-University of Bonn
30390439 51 Synthesis and biological evaluation of quinazoline derivatives - A SAR study of novel inhibitors of ABCG2.EBI University of Bonn
30384046 47 1,2,3,4-Tetrahydroisoquinoline/2H-chromen-2-one conjugates as nanomolar P-glycoprotein inhibitors: Molecular determinants for affinity and selectivity over multidrug resistance associated protein 1.EBI Universit£
31465686 355 Triazole Bridged Flavonoid Dimers as Potent, Nontoxic, and Highly Selective Breast Cancer Resistance Protein (BCRP/ABCG2) Inhibitors.EBI Hong Kong Polytechnic University
17129588 30 Dibenzocyclooctadiene lignans: a class of novel inhibitors of multidrug resistance-associated protein 1.EBI Zhejiang University
10188979 1 ATP- and glutathione-dependent transport of chemotherapeutic drugs by the multidrug resistance protein MRP1.EBI University Hospital Groningen
7961706 2 The MRP gene encodes an ATP-dependent export pump for leukotriene C4 and structurally related conjugates.EBI Deutsches Krebsforschungszentrum
8670053 3 ATP-dependent glutathione disulphide transport mediated by the MRP gene-encoded conjugate export pump.EBI Deutsches Krebsforschungszentrum
11102445 2 Glutathione stimulates sulfated estrogen transport by multidrug resistance protein 1.EBI Queen'S University
9647783 4 Doxorubicin- and daunorubicin-glutathione conjugates, but not unconjugated drugs, competitively inhibit leukotriene C4 transport mediated by MRP/GS-X pump.EBI University of Texas M. D. Anderson Cancer Center
30351934 24 Discovery of Novel Flavonoid Dimers To Reverse Multidrug Resistance Protein 1 (MRP1, ABCC1) Mediated Drug Resistance in Cancers Using a High Throughput Platform with "Click Chemistry".EBI Hong Kong Polytechnic University
29233614 2 Monoterpene indole alkaloid azine derivatives as MDR reversal agents.EBI Universidade De Lisboa
28841513 117 Synthesis and biological investigation of 2,4-substituted quinazolines as highly potent inhibitors of breast cancer resistance protein (ABCG2).EBI University of Bonn
28471656 91 4-Anilino-2-pyridylquinazolines and -pyrimidines as Highly Potent and Nontoxic Inhibitors of Breast Cancer Resistance Protein (ABCG2).EBI University of Bonn