The following articles (labelled with PubMed ID or TBD) are for your review
PMID | Data | Article Title | Organization |
28005385 |
98 |
Design and Synthesis of a Series of l-trans-4-Substituted Prolines as Selective Antagonists for the Ionotropic Glutamate Receptors Including Functional and X-ray Crystallographic Studies of New Subtype Selective Kainic Acid Receptor Subtype 1 (GluK1) Antagonist (2S,4R)-4-(2-Carboxyphenoxy)pyrrolidin |
Mcgill University |
26862980 |
37 |
Tweaking Subtype Selectivity and Agonist Efficacy at (S)-2-Amino-3-(3-hydroxy-5-methyl-isoxazol-4-yl)propionic acid (AMPA) Receptors in a Small Series of BnTetAMPA Analogues. |
University of Copenhagen |
26653877 |
47 |
Studies on Aryl-Substituted Phenylalanines: Synthesis, Activity, and Different Binding Modes at AMPA Receptors. |
University of Copenhagen |
23432124 |
2 |
Studies on an (S)-2-amino-3-(3-hydroxy-5-methyl-4-isoxazolyl)propionic acid (AMPA) receptor antagonist IKM-159: asymmetric synthesis, neuroactivity, and structural characterization. |
Yokohama City University |
23414088 |
102 |
Chemoenzymatic synthesis of new 2,4-syn-functionalized (S)-glutamate analogues and structure-activity relationship studies at ionotropic glutamate receptors and excitatory amino acid transporters. |
University of Copenhagen |
20408529 |
32 |
4-hydroxy-1,2,5-oxadiazol-3-yl moiety as bioisoster of the carboxy function. Synthesis, ionization constants, and molecular pharmacological characterization at ionotropic glutamate receptors of compounds related to glutamate and its homologues. |
Universit£ |
19588945 |
55 |
The glutamate receptor GluR5 agonist (S)-2-amino-3-(3-hydroxy-7,8-dihydro-6H-cyclohepta[d]isoxazol-4-yl)propionic acid and the 8-methyl analogue: synthesis, molecular pharmacology, and biostructural characterization. |
University of Copenhagen |
18811139 |
126 |
1H-cyclopentapyrimidine-2,4(1H,3H)-dione-related ionotropic glutamate receptors ligands. structure-activity relationships and identification of potent and Selective iGluR5 modulators. |
European Research Centre For Drug Discovery and Development (Natsyndrugs) |
18338843 |
57 |
Synthesis and pharmacological characterization at glutamate receptors of the four enantiopure isomers of tricholomic acid. |
Universit£ |
21619066 |
41 |
Selective kainate receptor (GluK1) ligands structurally based upon 1H-cyclopentapyrimidin-2,4(1H,3H)-dione: synthesis, molecular modeling, and pharmacological and biostructural characterization. |
University of Copenhagen |
21067182 |
37 |
Biostructural and Pharmacological Studies of Bicyclic Analogues of the 3-Isoxazolol Glutamate Receptor Agonist Ibotenic Acid |
TBA |
20096591 |
84 |
Developing a complete pharmacology for AMPA receptors: a perspective on subtype-selective ligands. |
University of California |
19656686 |
20 |
3-Substituted phenylalanines as selective AMPA- and kainate receptor ligands. |
University of Copenhagen |
17455929 |
36 |
A tetrazolyl-substituted subtype-selective AMPA receptor agonist. |
University of Copenhagen |
15615543 |
56 |
Bioisosteric modifications of 2-arylureidobenzoic acids: selective noncompetitive antagonists for the homomeric kainate receptor subtype GluR5. |
The Danish University of Pharmaceutical Sciences |
12747796 |
39 |
Design, synthesis, and pharmacology of a highly subtype-selective GluR1/2 agonist, (RS)-2-amino-3-(4-chloro-3-hydroxy-5-isoxazolyl)propionic acid (Cl-HIBO). |
The Danish University of Pharmaceutical Sciences |
11741469 |
8 |
Characterization of the 1H-cyclopentapyrimidine-2,4(1H,3H)-dione derivative (S)-CPW399 as a novel, potent, and subtype-selective AMPA receptor full agonist with partial desensitization properties. |
Universita' Degli Studi Di Siena |
30943028 |
66 |
Use of the 4-Hydroxytriazole Moiety as a Bioisosteric Tool in the Development of Ionotropic Glutamate Receptor Ligands. |
University of Turin |
24131202 |
6 |
Synthesis, pharmacological and structural characterization, and thermodynamic aspects of GluA2-positive allosteric modulators with a 3,4-dihydro-2H-1,2,4-benzothiadiazine 1,1-dioxide scaffold. |
University of Copenhagen |
28738307 |
13 |
Pharmacological characterization and binding modes of novel racemic and optically active phenylalanine-based antagonists of AMPA receptors. |
Jagiellonian University Medical College |
29451794 |
20 |
( S)-2-Amino-3-(5-methyl-3-hydroxyisoxazol-4-yl)propanoic Acid (AMPA) and Kainate Receptor Ligands: Further Exploration of Bioisosteric Replacements and Structural and Biological Investigation. |
University of Siena |