Found 8 hits for monomerid = 50028124 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
HTR7
(GUINEA PIG) | BDBM50028124
(2-(6-Methoxy-1H-indol-3-yl)-ethylamine | 2-(6-meth...)Show InChI InChI=1S/C11H14N2O/c1-14-9-2-3-10-8(4-5-12)7-13-11(10)6-9/h2-3,6-7,13H,4-5,12H2,1H3 | UniProtKB/SwissProt
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| Article PubMed
| 36.3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Syntex Discovery Research
Curated by PDSP Ki Database
| |
Br J Pharmacol 115: 107-16 (1995)
Article DOI: 10.1111/j.1476-5381.1995.tb16327.x BindingDB Entry DOI: 10.7270/Q2610XTR |
More data for this Ligand-Target Pair | |
HTR7
(GUINEA PIG) | BDBM50028124
(2-(6-Methoxy-1H-indol-3-yl)-ethylamine | 2-(6-meth...)Show InChI InChI=1S/C11H14N2O/c1-14-9-2-3-10-8(4-5-12)7-13-11(10)6-9/h2-3,6-7,13H,4-5,12H2,1H3 | UniProtKB/SwissProt
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| Article PubMed
| 363 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Syntex Discovery Research
Curated by PDSP Ki Database
| |
Br J Pharmacol 115: 107-16 (1995)
Article DOI: 10.1111/j.1476-5381.1995.tb16327.x BindingDB Entry DOI: 10.7270/Q2610XTR |
More data for this Ligand-Target Pair | |
Sodium-dependent dopamine transporter
(Rattus norvegicus (rat)) | BDBM50028124
(2-(6-Methoxy-1H-indol-3-yl)-ethylamine | 2-(6-meth...)Show InChI InChI=1S/C11H14N2O/c1-14-9-2-3-10-8(4-5-12)7-13-11(10)6-9/h2-3,6-7,13H,4-5,12H2,1H3 | Reactome pathway KEGG
UniProtKB/SwissProt
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| n/a | n/a | n/a | n/a | 113 | n/a | n/a | n/a | n/a |
Research Triangle Institute
Curated by ChEMBL
| Assay Description Induction of DAT-mediated dopamine release in rat brain synaptosomes by [3H]DA release assay |
Bioorg Med Chem Lett 24: 4754-8 (2014)
Article DOI: 10.1016/j.bmcl.2014.07.062 BindingDB Entry DOI: 10.7270/Q2416ZNK |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 2A
(Homo sapiens (Human)) | BDBM50028124
(2-(6-Methoxy-1H-indol-3-yl)-ethylamine | 2-(6-meth...)Show InChI InChI=1S/C11H14N2O/c1-14-9-2-3-10-8(4-5-12)7-13-11(10)6-9/h2-3,6-7,13H,4-5,12H2,1H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
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| n/a | n/a | n/a | n/a | 2.44E+3 | n/a | n/a | n/a | n/a |
Research Triangle Institute
Curated by ChEMBL
| Assay Description Agonist activity at 5HT2A receptor (unknown origin) by cell based calcium mobilization assay |
Bioorg Med Chem Lett 24: 4754-8 (2014)
Article DOI: 10.1016/j.bmcl.2014.07.062 BindingDB Entry DOI: 10.7270/Q2416ZNK |
More data for this Ligand-Target Pair | |
Serotonin (5-HT) receptor
(Rattus norvegicus-Rattus norvegicus (rat)-RAT-Ratt...) | BDBM50028124
(2-(6-Methoxy-1H-indol-3-yl)-ethylamine | 2-(6-meth...)Show InChI InChI=1S/C11H14N2O/c1-14-9-2-3-10-8(4-5-12)7-13-11(10)6-9/h2-3,6-7,13H,4-5,12H2,1H3 | PDB
UniProtKB/SwissProt
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| n/a | n/a | 630 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description In vitro inhibition of Angiotensin I converting enzyme |
J Med Chem 27: 41-5 (1984)
BindingDB Entry DOI: 10.7270/Q2F76BJN |
More data for this Ligand-Target Pair | |
Potassium voltage-gated channel subfamily B member 2
(Homo sapiens (Human)) | BDBM50028124
(2-(6-Methoxy-1H-indol-3-yl)-ethylamine | 2-(6-meth...)Show InChI InChI=1S/C11H14N2O/c1-14-9-2-3-10-8(4-5-12)7-13-11(10)6-9/h2-3,6-7,13H,4-5,12H2,1H3 | KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
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| n/a | n/a | 1.91E+12 | n/a | n/a | n/a | n/a | n/a | n/a |
Chinese Academy of Sciences
Curated by ChEMBL
| Assay Description Inhibition of voltage-gated potassium channel |
J Med Chem 50: 83-93 (2007)
Article DOI: 10.1021/jm060414o BindingDB Entry DOI: 10.7270/Q20R9S5C |
More data for this Ligand-Target Pair | |
Sodium-dependent serotonin transporter
(Rattus norvegicus (rat)) | BDBM50028124
(2-(6-Methoxy-1H-indol-3-yl)-ethylamine | 2-(6-meth...)Show InChI InChI=1S/C11H14N2O/c1-14-9-2-3-10-8(4-5-12)7-13-11(10)6-9/h2-3,6-7,13H,4-5,12H2,1H3 | PDB
KEGG
UniProtKB/SwissProt
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| n/a | n/a | n/a | n/a | 54 | n/a | n/a | n/a | n/a |
Research Triangle Institute
Curated by ChEMBL
| Assay Description Induction of 5-HTT-mediated 5-HT release in rat brain synaptosomes by [3H]5-HT release assay |
Bioorg Med Chem Lett 24: 4754-8 (2014)
Article DOI: 10.1016/j.bmcl.2014.07.062 BindingDB Entry DOI: 10.7270/Q2416ZNK |
More data for this Ligand-Target Pair | |
Norepinephrine Monoamine transporters
(Rattus norvegicus) | BDBM50028124
(2-(6-Methoxy-1H-indol-3-yl)-ethylamine | 2-(6-meth...)Show InChI InChI=1S/C11H14N2O/c1-14-9-2-3-10-8(4-5-12)7-13-11(10)6-9/h2-3,6-7,13H,4-5,12H2,1H3 | Reactome pathway KEGG
UniProtKB/TrEMBL
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| n/a | n/a | n/a | n/a | 465 | n/a | n/a | n/a | n/a |
Research Triangle Institute
Curated by ChEMBL
| Assay Description Induction of NET-mediated norepinephrine release in rat brain synaptosomes by [3H]NE release assay |
Bioorg Med Chem Lett 24: 4754-8 (2014)
Article DOI: 10.1016/j.bmcl.2014.07.062 BindingDB Entry DOI: 10.7270/Q2416ZNK |
More data for this Ligand-Target Pair | |