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BDBM96235 4-[2-hydroxy-3-(isopropylamino)propoxy]-3-methyl-coumarilic acid ethyl ester;hydrochloride::4-[2-hydroxy-3-(propan-2-ylamino)propoxy]-3-methyl-2-benzofurancarboxylic acid ethyl ester;hydrochloride::CHEMBL53849::MLS000039218::Non peptidic, 1::SMR000036354::cid_6602742::ethyl 3-methyl-4-[2-oxidanyl-3-(propan-2-ylamino)propoxy]-1-benzofuran-2-carboxylate;hydrochloride::ethyl 4-[2-hydroxy-3-(propan-2-ylamino)propoxy]-3-methyl-1-benzofuran-2-carboxylate;hydrochloride
SMILES: CCOC(=O)c1oc2cccc(OCC(O)CNC(C)C)c2c1C
InChI Key: InChIKey=QVJVMNUTCGTBCH-UHFFFAOYSA-N
| Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Myristoyl-CoA:protein N-myristoyltransferase (Nmt) (Candida albicans (Yeast)) | BDBM96235 (4-[2-hydroxy-3-(isopropylamino)propoxy]-3-methyl-c...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet  | Purchase CHEMBL PC cid PC sid PDB UniChem Similars | Article PubMed | 50 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Nippon Roche Research Center | Assay Description Inhibition activity against C. albicans Nmt and human Nmt as assessed by IC50 using myristoyl-CoA (0.5 uM) and peptide substrate GLTISKLFRR-NH2 (0.5 ... | Chem Biol 9: 1119-28 (2002) Article DOI: 10.1016/S1074-5521(02)00240-5 BindingDB Entry DOI: 10.7270/Q2BV7F0C | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Myristoyl-CoA:protein N-myristoyltransferase (Nmt) (Candida albicans (Yeast)) | BDBM96235 (4-[2-hydroxy-3-(isopropylamino)propoxy]-3-methyl-c...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid PDB UniChem Similars | Article PubMed | 140 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Nippon Roche Research Center | Assay Description Inhibition activity against C. albicans Nmt and human Nmt as assessed by IC50 using myristoyl-CoA (0.5 uM) and peptide substrate GLTISKLFRR-NH2 (0.5 ... | Chem Biol 9: 1119-28 (2002) Article DOI: 10.1016/S1074-5521(02)00240-5 BindingDB Entry DOI: 10.7270/Q2BV7F0C | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Myristoyl-CoA:protein N-myristoyltransferase (Nmt) (Candida albicans (Yeast)) | BDBM96235 (4-[2-hydroxy-3-(isopropylamino)propoxy]-3-methyl-c...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid PDB UniChem Similars | Article PubMed | 240 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Nippon Roche Research Center | Assay Description Inhibition activity against C. albicans Nmt and human Nmt as assessed by IC50 using myristoyl-CoA (0.5 uM) and peptide substrate GLTISKLFRR-NH2 (0.5 ... | Chem Biol 9: 1119-28 (2002) Article DOI: 10.1016/S1074-5521(02)00240-5 BindingDB Entry DOI: 10.7270/Q2BV7F0C | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Myristoyl-CoA:protein N-myristoyltransferase (Nmt) (Candida albicans (Yeast)) | BDBM96235 (4-[2-hydroxy-3-(isopropylamino)propoxy]-3-methyl-c...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid PDB UniChem Similars | Article PubMed | 260 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Nippon Roche Research Center | Assay Description Inhibition activity against C. albicans Nmt and human Nmt as assessed by IC50 using myristoyl-CoA (0.5 uM) and peptide substrate GLTISKLFRR-NH2 (0.5 ... | Chem Biol 9: 1119-28 (2002) Article DOI: 10.1016/S1074-5521(02)00240-5 BindingDB Entry DOI: 10.7270/Q2BV7F0C | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Myristoyl-CoA:protein N-myristoyltransferase (Nmt) (Candida albicans (Yeast)) | BDBM96235 (4-[2-hydroxy-3-(isopropylamino)propoxy]-3-methyl-c...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid PDB UniChem Similars | Article PubMed | 280 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Nippon Roche Research Center | Assay Description Inhibition activity against C. albicans Nmt and human Nmt as assessed by IC50 using myristoyl-CoA (0.5 uM) and peptide substrate GLTISKLFRR-NH2 (0.5 ... | Chem Biol 9: 1119-28 (2002) Article DOI: 10.1016/S1074-5521(02)00240-5 BindingDB Entry DOI: 10.7270/Q2BV7F0C | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Myristoyl-CoA:protein N-myristoyltransferase (Nmt) (Candida albicans (Yeast)) | BDBM96235 (4-[2-hydroxy-3-(isopropylamino)propoxy]-3-methyl-c...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid PDB UniChem Similars | Article PubMed | 360 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Nippon Roche Research Center | Assay Description Inhibition activity against C. albicans Nmt and human Nmt as assessed by IC50 using myristoyl-CoA (0.5 uM) and peptide substrate GLTISKLFRR-NH2 (0.5 ... | Chem Biol 9: 1119-28 (2002) Article DOI: 10.1016/S1074-5521(02)00240-5 BindingDB Entry DOI: 10.7270/Q2BV7F0C | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Myristoyl-CoA:protein N-myristoyltransferase (Nmt) (Candida albicans (Yeast)) | BDBM96235 (4-[2-hydroxy-3-(isopropylamino)propoxy]-3-methyl-c...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid PDB UniChem Similars | Article PubMed | 390 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Nippon Roche Research Center | Assay Description Inhibition activity against C. albicans Nmt and human Nmt as assessed by IC50 using myristoyl-CoA (0.5 uM) and peptide substrate GLTISKLFRR-NH2 (0.5 ... | Chem Biol 9: 1119-28 (2002) Article DOI: 10.1016/S1074-5521(02)00240-5 BindingDB Entry DOI: 10.7270/Q2BV7F0C | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Myristoyl-CoA:protein N-myristoyltransferase (Nmt) (Candida albicans (Yeast)) | BDBM96235 (4-[2-hydroxy-3-(isopropylamino)propoxy]-3-methyl-c...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid PDB UniChem Similars | Article PubMed | 420 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Nippon Roche Research Center | Assay Description Inhibition activity against C. albicans Nmt and human Nmt as assessed by IC50 using myristoyl-CoA (0.5 uM) and peptide substrate GLTISKLFRR-NH2 (0.5 ... | Chem Biol 9: 1119-28 (2002) Article DOI: 10.1016/S1074-5521(02)00240-5 BindingDB Entry DOI: 10.7270/Q2BV7F0C | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Myristoyl-CoA:protein N-myristoyltransferase (Nmt) (Candida albicans (Yeast)) | BDBM96235 (4-[2-hydroxy-3-(isopropylamino)propoxy]-3-methyl-c...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid PDB UniChem Similars | Article PubMed | 450 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Nippon Roche Research Center | Assay Description Inhibition activity against C. albicans Nmt and human Nmt as assessed by IC50 using myristoyl-CoA (0.5 uM) and peptide substrate GLTISKLFRR-NH2 (0.5 ... | Chem Biol 9: 1119-28 (2002) Article DOI: 10.1016/S1074-5521(02)00240-5 BindingDB Entry DOI: 10.7270/Q2BV7F0C | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Myristoyl-CoA:protein N-myristoyltransferase (Nmt) (Candida albicans (Yeast)) | BDBM96235 (4-[2-hydroxy-3-(isopropylamino)propoxy]-3-methyl-c...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid PDB UniChem Similars | Article PubMed | 450 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Nippon Roche Research Center | Assay Description Inhibition activity against C. albicans Nmt and human Nmt as assessed by IC50 using myristoyl-CoA (0.5 uM) and peptide substrate GLTISKLFRR-NH2 (0.5 ... | Chem Biol 9: 1119-28 (2002) Article DOI: 10.1016/S1074-5521(02)00240-5 BindingDB Entry DOI: 10.7270/Q2BV7F0C | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Myristoyl-CoA:protein N-myristoyltransferase (Nmt) (Candida albicans (Yeast)) | BDBM96235 (4-[2-hydroxy-3-(isopropylamino)propoxy]-3-methyl-c...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid PDB UniChem Similars | Article PubMed | 450 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Nippon Roche Research Center | Assay Description Inhibition activity against C. albicans Nmt and human Nmt as assessed by IC50 using myristoyl-CoA (0.5 uM) and peptide substrate GLTISKLFRR-NH2 (0.5 ... | Chem Biol 9: 1119-28 (2002) Article DOI: 10.1016/S1074-5521(02)00240-5 BindingDB Entry DOI: 10.7270/Q2BV7F0C | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Myristoyl-CoA:protein N-myristoyltransferase (Nmt) (Candida albicans (Yeast)) | BDBM96235 (4-[2-hydroxy-3-(isopropylamino)propoxy]-3-methyl-c...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid PDB UniChem Similars | Article PubMed | 540 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Nippon Roche Research Center | Assay Description Inhibition activity against C. albicans Nmt and human Nmt as assessed by IC50 using myristoyl-CoA (0.5 uM) and peptide substrate GLTISKLFRR-NH2 (0.5 ... | Chem Biol 9: 1119-28 (2002) Article DOI: 10.1016/S1074-5521(02)00240-5 BindingDB Entry DOI: 10.7270/Q2BV7F0C | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Myristoyl-CoA:protein N-myristoyltransferase (Nmt) (Candida albicans (Yeast)) | BDBM96235 (4-[2-hydroxy-3-(isopropylamino)propoxy]-3-methyl-c...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid PDB UniChem Similars | Article PubMed | 540 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Nippon Roche Research Center | Assay Description Inhibition activity against C. albicans Nmt and human Nmt as assessed by IC50 using myristoyl-CoA (0.5 uM) and peptide substrate GLTISKLFRR-NH2 (0.5 ... | Chem Biol 9: 1119-28 (2002) Article DOI: 10.1016/S1074-5521(02)00240-5 BindingDB Entry DOI: 10.7270/Q2BV7F0C | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Myristoyl-CoA:protein N-myristoyltransferase (Nmt) (Candida albicans (Yeast)) | BDBM96235 (4-[2-hydroxy-3-(isopropylamino)propoxy]-3-methyl-c...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid PDB UniChem Similars | Article PubMed | 600 | n/a | 980 | n/a | n/a | n/a | n/a | n/a | n/a |
Nippon Roche Research Center | Assay Description Inhibition activity against C. albicans Nmt and human Nmt as assessed by IC50 using myristoyl-CoA (0.5 uM) and peptide substrate GLTISKLFRR-NH2 (0.5 ... | Chem Biol 9: 1119-28 (2002) Article DOI: 10.1016/S1074-5521(02)00240-5 BindingDB Entry DOI: 10.7270/Q2BV7F0C | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Myristoyl-CoA:protein N-myristoyltransferase (Nmt) (Candida albicans (Yeast)) | BDBM96235 (4-[2-hydroxy-3-(isopropylamino)propoxy]-3-methyl-c...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid PDB UniChem Similars | Article PubMed | 690 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Nippon Roche Research Center | Assay Description Inhibition activity against C. albicans Nmt and human Nmt as assessed by IC50 using myristoyl-CoA (0.5 uM) and peptide substrate GLTISKLFRR-NH2 (0.5 ... | Chem Biol 9: 1119-28 (2002) Article DOI: 10.1016/S1074-5521(02)00240-5 BindingDB Entry DOI: 10.7270/Q2BV7F0C | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Myristoyl-CoA:protein N-myristoyltransferase (Nmt) (Candida albicans (Yeast)) | BDBM96235 (4-[2-hydroxy-3-(isopropylamino)propoxy]-3-methyl-c...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid PDB UniChem Similars | Article PubMed | 860 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Nippon Roche Research Center | Assay Description Inhibition activity against C. albicans Nmt and human Nmt as assessed by IC50 using myristoyl-CoA (0.5 uM) and peptide substrate GLTISKLFRR-NH2 (0.5 ... | Chem Biol 9: 1119-28 (2002) Article DOI: 10.1016/S1074-5521(02)00240-5 BindingDB Entry DOI: 10.7270/Q2BV7F0C | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Myristoyl-CoA:protein N-myristoyltransferase (Nmt) (Candida albicans (Yeast)) | BDBM96235 (4-[2-hydroxy-3-(isopropylamino)propoxy]-3-methyl-c...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid PDB UniChem Similars | Article PubMed | 890 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Nippon Roche Research Center | Assay Description Inhibition activity against C. albicans Nmt and human Nmt as assessed by IC50 using myristoyl-CoA (0.5 uM) and peptide substrate GLTISKLFRR-NH2 (0.5 ... | Chem Biol 9: 1119-28 (2002) Article DOI: 10.1016/S1074-5521(02)00240-5 BindingDB Entry DOI: 10.7270/Q2BV7F0C | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Myristoyl-CoA:protein N-myristoyltransferase (Nmt) (Candida albicans (Yeast)) | BDBM96235 (4-[2-hydroxy-3-(isopropylamino)propoxy]-3-methyl-c...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid PDB UniChem Similars | Article PubMed | 1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Nippon Roche Research Center | Assay Description Inhibition activity against C. albicans Nmt and human Nmt as assessed by IC50 using myristoyl-CoA (0.5 uM) and peptide substrate GLTISKLFRR-NH2 (0.5 ... | Chem Biol 9: 1119-28 (2002) Article DOI: 10.1016/S1074-5521(02)00240-5 BindingDB Entry DOI: 10.7270/Q2BV7F0C | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Myristoyl-CoA:protein N-myristoyltransferase (Nmt) (Candida albicans (Yeast)) | BDBM96235 (4-[2-hydroxy-3-(isopropylamino)propoxy]-3-methyl-c...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid PDB UniChem Similars | Article PubMed | 1.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Nippon Roche Research Center | Assay Description Inhibition activity against C. albicans Nmt and human Nmt as assessed by IC50 using myristoyl-CoA (0.5 uM) and peptide substrate GLTISKLFRR-NH2 (0.5 ... | Chem Biol 9: 1119-28 (2002) Article DOI: 10.1016/S1074-5521(02)00240-5 BindingDB Entry DOI: 10.7270/Q2BV7F0C | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Myristoyl-CoA:protein N-myristoyltransferase (Nmt) (Candida albicans (Yeast)) | BDBM96235 (4-[2-hydroxy-3-(isopropylamino)propoxy]-3-methyl-c...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid PDB UniChem Similars | Article PubMed | 1.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Nippon Roche Research Center | Assay Description Inhibition activity against C. albicans Nmt and human Nmt as assessed by IC50 using myristoyl-CoA (0.5 uM) and peptide substrate GLTISKLFRR-NH2 (0.5 ... | Chem Biol 9: 1119-28 (2002) Article DOI: 10.1016/S1074-5521(02)00240-5 BindingDB Entry DOI: 10.7270/Q2BV7F0C | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Myristoyl-CoA:protein N-myristoyltransferase (Nmt) (Candida albicans (Yeast)) | BDBM96235 (4-[2-hydroxy-3-(isopropylamino)propoxy]-3-methyl-c...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid PDB UniChem Similars | Article PubMed | 1.90E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Nippon Roche Research Center | Assay Description Inhibition activity against C. albicans Nmt and human Nmt as assessed by IC50 using myristoyl-CoA (0.5 uM) and peptide substrate GLTISKLFRR-NH2 (0.5 ... | Chem Biol 9: 1119-28 (2002) Article DOI: 10.1016/S1074-5521(02)00240-5 BindingDB Entry DOI: 10.7270/Q2BV7F0C | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Myristoyl-CoA:protein N-myristoyltransferase (Nmt) (Candida albicans (Yeast)) | BDBM96235 (4-[2-hydroxy-3-(isopropylamino)propoxy]-3-methyl-c...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid PDB UniChem Similars | Article PubMed | 2.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Nippon Roche Research Center | Assay Description Inhibition activity against C. albicans Nmt and human Nmt as assessed by IC50 using myristoyl-CoA (0.5 uM) and peptide substrate GLTISKLFRR-NH2 (0.5 ... | Chem Biol 9: 1119-28 (2002) Article DOI: 10.1016/S1074-5521(02)00240-5 BindingDB Entry DOI: 10.7270/Q2BV7F0C | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Myristoyl-CoA:protein N-myristoyltransferase (Nmt) (Candida albicans (Yeast)) | BDBM96235 (4-[2-hydroxy-3-(isopropylamino)propoxy]-3-methyl-c...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid PDB UniChem Similars | Article PubMed | 2.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Nippon Roche Research Center | Assay Description Inhibition activity against C. albicans Nmt and human Nmt as assessed by IC50 using myristoyl-CoA (0.5 uM) and peptide substrate GLTISKLFRR-NH2 (0.5 ... | Chem Biol 9: 1119-28 (2002) Article DOI: 10.1016/S1074-5521(02)00240-5 BindingDB Entry DOI: 10.7270/Q2BV7F0C | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Myristoyl-CoA:protein N-myristoyltransferase (Nmt) (Candida albicans (Yeast)) | BDBM96235 (4-[2-hydroxy-3-(isopropylamino)propoxy]-3-methyl-c...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid PDB UniChem Similars | Article PubMed | 6.90E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Nippon Roche Research Center | Assay Description Inhibition activity against C. albicans Nmt and human Nmt as assessed by IC50 using myristoyl-CoA (0.5 uM) and peptide substrate GLTISKLFRR-NH2 (0.5 ... | Chem Biol 9: 1119-28 (2002) Article DOI: 10.1016/S1074-5521(02)00240-5 BindingDB Entry DOI: 10.7270/Q2BV7F0C | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Myristoyl-CoA:protein N-myristoyltransferase (Nmt) (Candida albicans (Yeast)) | BDBM96235 (4-[2-hydroxy-3-(isopropylamino)propoxy]-3-methyl-c...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid PDB UniChem Similars | Article PubMed | >8.90E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Nippon Roche Research Center | Assay Description Inhibition activity against C. albicans Nmt and human Nmt as assessed by IC50 using myristoyl-CoA (0.5 uM) and peptide substrate GLTISKLFRR-NH2 (0.5 ... | Chem Biol 9: 1119-28 (2002) Article DOI: 10.1016/S1074-5521(02)00240-5 BindingDB Entry DOI: 10.7270/Q2BV7F0C | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Myristoyl-CoA:protein N-myristoyltransferase (Nmt) (Candida albicans (Yeast)) | BDBM96235 (4-[2-hydroxy-3-(isopropylamino)propoxy]-3-methyl-c...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid PDB UniChem Similars | Article | n/a | n/a | 2.27E+8 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of candida N-myristoyltransferase | Citation and Details Article DOI: 10.1007/s00044-008-9120-5 BindingDB Entry DOI: 10.7270/Q2XD14KS | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Adrenergic receptor beta (Homo sapiens (Human)) | BDBM96235 (4-[2-hydroxy-3-(isopropylamino)propoxy]-3-methyl-c...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid PDB UniChem Similars | PubMed | n/a | n/a | 98 | n/a | n/a | n/a | n/a | n/a | n/a |
Nippon Roche Research Center Curated by ChEMBL | Assay Description Compound was evaluated for its Beta adrenergic receptor blocking action | Bioorg Med Chem Lett 11: 1833-7 (2001) BindingDB Entry DOI: 10.7270/Q2KS6TRW | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Peptide N-myristoyltransferase (Homo sapiens (Human)) | BDBM96235 (4-[2-hydroxy-3-(isopropylamino)propoxy]-3-methyl-c...) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid PDB UniChem Similars | PubMed | n/a | n/a | 980 | n/a | n/a | n/a | n/a | n/a | n/a |
Nippon Roche Research Center Curated by ChEMBL | Assay Description Inhibitory activity against Candida albicans N-myristoyltransferase (CaNmt) | Bioorg Med Chem Lett 11: 1833-7 (2001) BindingDB Entry DOI: 10.7270/Q2KS6TRW | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Peptide N-myristoyltransferase (Homo sapiens (Human)) | BDBM96235 (4-[2-hydroxy-3-(isopropylamino)propoxy]-3-methyl-c...) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid PDB UniChem Similars | PubMed | n/a | n/a | 1.94E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Nippon Roche Research Center Curated by ChEMBL | Assay Description In vitro ability of the compound to displace radiolabelled FTI from farnesyltransferase in cultured Ha-ras transformed RAT1 cells | Bioorg Med Chem Lett 11: 1833-7 (2001) BindingDB Entry DOI: 10.7270/Q2KS6TRW | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Fructose-1,6-bisphosphate aldolase (FBA) (Mycobacterium tuberculosis (strain H37Rv)) | BDBM96235 (4-[2-hydroxy-3-(isopropylamino)propoxy]-3-methyl-c...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid PDB UniChem Similars | PCBioAssay | n/a | n/a | 843 | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute Molecular Screening Center Curated by PubChem BioAssay | PubChem Bioassay (2013) BindingDB Entry DOI: 10.7270/Q25719N6 | ||||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Myristoyl-CoA:protein N-myristoyltransferase (Nmt) (Candida albicans (Yeast)) | BDBM96235 (4-[2-hydroxy-3-(isopropylamino)propoxy]-3-methyl-c...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid PDB UniChem Similars | Article | n/a | n/a | 980 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of candida N-myristoyltransferase | Citation and Details Article DOI: 10.1007/s00044-008-9120-5 BindingDB Entry DOI: 10.7270/Q2XD14KS | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Myristoyl-CoA:protein N-myristoyltransferase (Nmt) (Homo sapiens (Human)) | BDBM96235 (4-[2-hydroxy-3-(isopropylamino)propoxy]-3-methyl-c...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid PDB UniChem Similars | Article PubMed | n/a | n/a | 1.94E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Nippon Roche Research Center | Assay Description Inhibition activity against C. albicans Nmt and human Nmt as assessed by IC50 using myristoyl-CoA (0.5 uM) and peptide substrate GLTISKLFRR-NH2 (0.5 ... | Chem Biol 9: 1119-28 (2002) Article DOI: 10.1016/S1074-5521(02)00240-5 BindingDB Entry DOI: 10.7270/Q2BV7F0C | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
