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BDBM357013 5-Phenyl-N-(pyridin-2-ylmethyl)-2-(pyrimidin-5-yl)quinazolin-4-amine::US10214511, Example 1

SMILES:

InChI Key:

Data: 19 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 19 hits for monomerid = 357013   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Glycogen synthase kinase-3 beta


(Homo sapiens (Human))
BDBM357013
PNG
(5-Phenyl-N-(pyridin-2-ylmethyl)-2-(pyrimidin-5-yl)...)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 5.00E+4n/an/an/an/an/an/a



Bristol-Myers Squibb Company

US Patent




US Patent US10214511 (2019)

More data for this
Ligand-Target Pair
Non-receptor tyrosine-protein kinase TYK2


(Homo sapiens (Human))
BDBM357013
PNG
(5-Phenyl-N-(pyridin-2-ylmethyl)-2-(pyrimidin-5-yl)...)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 5.00E+4n/an/an/an/an/an/a



Bristol-Myers Squibb Company

US Patent




US Patent US10214511 (2019)

More data for this
Ligand-Target Pair
Interleukin-1 receptor-associated kinase 4


(Homo sapiens (Human))
BDBM357013
PNG
(5-Phenyl-N-(pyridin-2-ylmethyl)-2-(pyrimidin-5-yl)...)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 5.00E+4n/an/an/an/an/an/a



Bristol-Myers Squibb Company

US Patent




US Patent US10214511 (2019)

More data for this
Ligand-Target Pair
Interleukin-1 receptor-associated kinase 1


(Homo sapiens (Human))
BDBM357013
PNG
(5-Phenyl-N-(pyridin-2-ylmethyl)-2-(pyrimidin-5-yl)...)
KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 5.00E+4n/an/an/an/an/an/a



Bristol-Myers Squibb Company

US Patent




US Patent US10214511 (2019)

More data for this
Ligand-Target Pair
Aurora kinase B


(Homo sapiens (Human))
BDBM357013
PNG
(5-Phenyl-N-(pyridin-2-ylmethyl)-2-(pyrimidin-5-yl)...)
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 5.00E+4n/an/an/an/an/an/a



Bristol-Myers Squibb Company

US Patent




US Patent US10214511 (2019)

More data for this
Ligand-Target Pair
Cytoplasmic tyrosine-protein kinase BMX


(Homo sapiens (Human))
BDBM357013
PNG
(5-Phenyl-N-(pyridin-2-ylmethyl)-2-(pyrimidin-5-yl)...)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 5.00E+4n/an/an/an/an/an/a



Bristol-Myers Squibb Company

US Patent




US Patent US10214511 (2019)

More data for this
Ligand-Target Pair
Tyrosine-protein kinase BTK


(Homo sapiens (Human))
BDBM357013
PNG
(5-Phenyl-N-(pyridin-2-ylmethyl)-2-(pyrimidin-5-yl)...)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 5.00E+4n/an/an/an/an/an/a



Bristol-Myers Squibb Company

US Patent




US Patent US10214511 (2019)

More data for this
Ligand-Target Pair
CDK2/CycE


(Homo sapiens (Human))
BDBM357013
PNG
(5-Phenyl-N-(pyridin-2-ylmethyl)-2-(pyrimidin-5-yl)...)
PDB

UniProtKB/SwissProt

antibodypedia
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 5.00E+4n/an/an/an/an/an/a



Bristol-Myers Squibb Company

US Patent




US Patent US10214511 (2019)

More data for this
Ligand-Target Pair
Interleukin-1 receptor-associated kinase 1


(Homo sapiens (Human))
BDBM357013
PNG
(5-Phenyl-N-(pyridin-2-ylmethyl)-2-(pyrimidin-5-yl)...)
KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 5.00E+4n/an/an/an/an/an/a



Bristol-Myers Squibb Company

US Patent




US Patent US10214511 (2019)

More data for this
Ligand-Target Pair
Tyrosine-protein kinase ITK/TSK


(Homo sapiens (Human))
BDBM357013
PNG
(5-Phenyl-N-(pyridin-2-ylmethyl)-2-(pyrimidin-5-yl)...)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 5.00E+4n/an/an/an/an/an/a



Bristol-Myers Squibb Company

US Patent




US Patent US10214511 (2019)

More data for this
Ligand-Target Pair
Tyrosine-protein kinase JAK2


(Homo sapiens (Human))
BDBM357013
PNG
(5-Phenyl-N-(pyridin-2-ylmethyl)-2-(pyrimidin-5-yl)...)
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 2.39E+4n/an/an/an/an/an/a



Bristol-Myers Squibb Company

US Patent




US Patent US10214511 (2019)

More data for this
Ligand-Target Pair
Tyrosine-protein kinase JAK3


(Homo sapiens (Human))
BDBM357013
PNG
(5-Phenyl-N-(pyridin-2-ylmethyl)-2-(pyrimidin-5-yl)...)
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 5.00E+4n/an/an/an/an/an/a



Bristol-Myers Squibb Company

US Patent




US Patent US10214511 (2019)

More data for this
Ligand-Target Pair
Tyrosine-protein kinase Lck


(Homo sapiens (Human))
BDBM357013
PNG
(5-Phenyl-N-(pyridin-2-ylmethyl)-2-(pyrimidin-5-yl)...)
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 5.00E+4n/an/an/an/an/an/a



Bristol-Myers Squibb Company

US Patent




US Patent US10214511 (2019)

More data for this
Ligand-Target Pair
Tyrosine-protein kinase Lyn


(Homo sapiens (Human))
BDBM357013
PNG
(5-Phenyl-N-(pyridin-2-ylmethyl)-2-(pyrimidin-5-yl)...)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 5.00E+4n/an/an/an/an/an/a



Bristol-Myers Squibb Company

US Patent




US Patent US10214511 (2019)

More data for this
Ligand-Target Pair
Nuclear receptor subfamily 2 group C member 2


(Homo sapiens (Human))
BDBM357013
PNG
(5-Phenyl-N-(pyridin-2-ylmethyl)-2-(pyrimidin-5-yl)...)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 5.00E+4n/an/an/an/an/an/a



Bristol-Myers Squibb Company

US Patent




US Patent US10214511 (2019)

More data for this
Ligand-Target Pair
Serine/threonine-protein kinase TBK1


(Homo sapiens (Human))
BDBM357013
PNG
(5-Phenyl-N-(pyridin-2-ylmethyl)-2-(pyrimidin-5-yl)...)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 5.00E+4n/an/an/an/an/an/a



Bristol-Myers Squibb Company

US Patent




US Patent US10214511 (2019)

More data for this
Ligand-Target Pair
Tyrosine-protein kinase TEC


(Homo sapiens (Human))
BDBM357013
PNG
(5-Phenyl-N-(pyridin-2-ylmethyl)-2-(pyrimidin-5-yl)...)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 5.00E+4n/an/an/an/an/an/a



Bristol-Myers Squibb Company

US Patent




US Patent US10214511 (2019)

More data for this
Ligand-Target Pair
Tyrosine-protein kinase TXK


(Homo sapiens (Human))
BDBM357013
PNG
(5-Phenyl-N-(pyridin-2-ylmethyl)-2-(pyrimidin-5-yl)...)
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 5.00E+4n/an/an/an/an/an/a



Bristol-Myers Squibb Company

US Patent




US Patent US10214511 (2019)

More data for this
Ligand-Target Pair
Inhibitor of nuclear factor kappa-B kinase subunit epsilon


(Homo sapiens (Human))
BDBM357013
PNG
(5-Phenyl-N-(pyridin-2-ylmethyl)-2-(pyrimidin-5-yl)...)
Reactome pathway
KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 5.00E+4n/an/an/an/an/an/a



Bristol-Myers Squibb Company

US Patent




US Patent US10214511 (2019)

More data for this
Ligand-Target Pair