null

SMILES: CP(C)(=O)c1c(F)cccc1-c1ccc(N2CC[C@@H](NC(=O)Nc3ccc(Cl)cc3F)C2=O)c(F)c1F

InChI Key: InChIKey=WYWXVASZSLSEEG-LJQANCHMSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 450307   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
N-formyl peptide receptor 2 (Homo sapiens (Human))	BDBM450307 (US10676431, Example 70 | US11117861, Example 70) Show SMILES CP(C)(=O)c1c(F)cccc1-c1ccc(N2CC[C@@H](NC(=O)Nc3ccc(Cl)cc3F)C2=O)c(F)c1F |r| Show InChI InChI=1S/C25H21ClF4N3O3P/c1-37(2,36)23-15(4-3-5-16(23)27)14-7-9-20(22(30)21(14)29)33-11-10-19(24(33)34)32-25(35)31-18-8-6-13(26)12-17(18)28/h3-9,12,19H,10-11H2,1-2H3,(H2,31,32,35)/t19-/m1/s1	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	0.0770	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company US Patent					Assay Description A mixture of forskolin (5 μM final for FPR2 or 10 μM final for FPR1) and IBMX (200 μM final) were added to 384-well Proxiplates (Perki...				US Patent US10676431 (2020)
					More data for this Ligand-Target Pair
fMet-Leu-Phe receptor (Homo sapiens (Human))	BDBM450307 (US10676431, Example 70 | US11117861, Example 70) Show SMILES CP(C)(=O)c1c(F)cccc1-c1ccc(N2CC[C@@H](NC(=O)Nc3ccc(Cl)cc3F)C2=O)c(F)c1F |r| Show InChI InChI=1S/C25H21ClF4N3O3P/c1-37(2,36)23-15(4-3-5-16(23)27)14-7-9-20(22(30)21(14)29)33-11-10-19(24(33)34)32-25(35)31-18-8-6-13(26)12-17(18)28/h3-9,12,19H,10-11H2,1-2H3,(H2,31,32,35)/t19-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	n/a	n/a	20	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
N-formyl peptide receptor 2 (Homo sapiens (Human))	BDBM450307 (US10676431, Example 70 | US11117861, Example 70) Show SMILES CP(C)(=O)c1c(F)cccc1-c1ccc(N2CC[C@@H](NC(=O)Nc3ccc(Cl)cc3F)C2=O)c(F)c1F |r| Show InChI InChI=1S/C25H21ClF4N3O3P/c1-37(2,36)23-15(4-3-5-16(23)27)14-7-9-20(22(30)21(14)29)33-11-10-19(24(33)34)32-25(35)31-18-8-6-13(26)12-17(18)28/h3-9,12,19H,10-11H2,1-2H3,(H2,31,32,35)/t19-/m1/s1	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	n/a	n/a	0.0770	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
fMet-Leu-Phe receptor (Homo sapiens (Human))	BDBM450307 (US10676431, Example 70 | US11117861, Example 70) Show SMILES CP(C)(=O)c1c(F)cccc1-c1ccc(N2CC[C@@H](NC(=O)Nc3ccc(Cl)cc3F)C2=O)c(F)c1F |r| Show InChI InChI=1S/C25H21ClF4N3O3P/c1-37(2,36)23-15(4-3-5-16(23)27)14-7-9-20(22(30)21(14)29)33-11-10-19(24(33)34)32-25(35)31-18-8-6-13(26)12-17(18)28/h3-9,12,19H,10-11H2,1-2H3,(H2,31,32,35)/t19-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	20	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company US Patent					Assay Description A mixture of forskolin (5 μM final for FPR2 or 10 μM final for FPR1) and IBMX (200 μM final) were added to 384-well Proxiplates (Perki...				US Patent US10676431 (2020)
					More data for this Ligand-Target Pair