BDBM50204483 7-phenyl-1-(5-(trifluoromethyl)oxazol-2-yl)heptan-1-one::CHEMBL373606

SMILES: FC(F)(F)c1cnc(o1)C(=O)CCCCCCc1ccccc1

InChI Key: InChIKey=GBJNNWLWHPYARC-UHFFFAOYSA-N

Data: 4 KI  7 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 11 hits for monomerid = 50204483   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Fatty-acid amide hydrolase 1 (aa 30-579) (Rattus norvegicus (rat))	BDBM50204483 (7-phenyl-1-(5-(trifluoromethyl)oxazol-2-yl)heptan-...) Show SMILES FC(F)(F)c1cnc(o1)C(=O)CCCCCCc1ccccc1 Show InChI InChI=1S/C17H18F3NO2/c18-17(19,20)15-12-21-16(23-15)14(22)11-7-2-1-4-8-13-9-5-3-6-10-13/h3,5-6,9-10,12H,1-2,4,7-8,11H2	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	0.800	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Inhibition of rat FAAH				Bioorg Med Chem Lett 18: 5842-6 (2008) Article DOI: 10.1016/j.bmcl.2008.06.084 BindingDB Entry DOI: 10.7270/Q2DN44V8
					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 (Homo sapiens (Human))	BDBM50204483 (7-phenyl-1-(5-(trifluoromethyl)oxazol-2-yl)heptan-...) Show SMILES FC(F)(F)c1cnc(o1)C(=O)CCCCCCc1ccccc1 Show InChI InChI=1S/C17H18F3NO2/c18-17(19,20)15-12-21-16(23-15)14(22)11-7-2-1-4-8-13-9-5-3-6-10-13/h3,5-6,9-10,12H,1-2,4,7-8,11H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	0.800	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Inhibition of rat recombinant FAAH expressed in Escherichia coli by [14C]oleamide breakdown				J Med Chem 50: 1058-68 (2007) Article DOI: 10.1021/jm0611509 BindingDB Entry DOI: 10.7270/Q26H4J6G
					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 (Homo sapiens (Human))	BDBM50204483 (7-phenyl-1-(5-(trifluoromethyl)oxazol-2-yl)heptan-...) Show SMILES FC(F)(F)c1cnc(o1)C(=O)CCCCCCc1ccccc1 Show InChI InChI=1S/C17H18F3NO2/c18-17(19,20)15-12-21-16(23-15)14(22)11-7-2-1-4-8-13-9-5-3-6-10-13/h3,5-6,9-10,12H,1-2,4,7-8,11H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	0.800	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Inhibition of FAAH				J Med Chem 54: 2529-91 (2011) Article DOI: 10.1021/jm1013693 BindingDB Entry DOI: 10.7270/Q24M95PH
					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 (aa 30-579) (Rattus norvegicus (rat))	BDBM50204483 (7-phenyl-1-(5-(trifluoromethyl)oxazol-2-yl)heptan-...) Show SMILES FC(F)(F)c1cnc(o1)C(=O)CCCCCCc1ccccc1 Show InChI InChI=1S/C17H18F3NO2/c18-17(19,20)15-12-21-16(23-15)14(22)11-7-2-1-4-8-13-9-5-3-6-10-13/h3,5-6,9-10,12H,1-2,4,7-8,11H2	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	0.800	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research& Development Curated by ChEMBL					Assay Description Inhibition of rat FAAH				Bioorg Med Chem 16: 1562-95 (2008) Article DOI: 10.1016/j.bmc.2007.11.015 BindingDB Entry DOI: 10.7270/Q21J9BNH
					More data for this Ligand-Target Pair
Neutral cholesterol ester hydrolase 1 (Homo sapiens (Human))	BDBM50204483 (7-phenyl-1-(5-(trifluoromethyl)oxazol-2-yl)heptan-...) Show SMILES FC(F)(F)c1cnc(o1)C(=O)CCCCCCc1ccccc1 Show InChI InChI=1S/C17H18F3NO2/c18-17(19,20)15-12-21-16(23-15)14(22)11-7-2-1-4-8-13-9-5-3-6-10-13/h3,5-6,9-10,12H,1-2,4,7-8,11H2	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Inhibition of KIAA1363				J Med Chem 50: 1058-68 (2007) Article DOI: 10.1021/jm0611509 BindingDB Entry DOI: 10.7270/Q26H4J6G
					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 (Homo sapiens (Human))	BDBM50204483 (7-phenyl-1-(5-(trifluoromethyl)oxazol-2-yl)heptan-...) Show SMILES FC(F)(F)c1cnc(o1)C(=O)CCCCCCc1ccccc1 Show InChI InChI=1S/C17H18F3NO2/c18-17(19,20)15-12-21-16(23-15)14(22)11-7-2-1-4-8-13-9-5-3-6-10-13/h3,5-6,9-10,12H,1-2,4,7-8,11H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	77	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Inhibition of rat recombinant FAAH expressed in Escherichia coli by [14C]oleamide breakdown				J Med Chem 50: 1058-68 (2007) Article DOI: 10.1021/jm0611509 BindingDB Entry DOI: 10.7270/Q26H4J6G
					More data for this Ligand-Target Pair
Sn1-specific diacylglycerol lipase alpha (Homo sapiens (Human))	BDBM50204483 (7-phenyl-1-(5-(trifluoromethyl)oxazol-2-yl)heptan-...) Show SMILES FC(F)(F)c1cnc(o1)C(=O)CCCCCCc1ccccc1 Show InChI InChI=1S/C17H18F3NO2/c18-17(19,20)15-12-21-16(23-15)14(22)11-7-2-1-4-8-13-9-5-3-6-10-13/h3,5-6,9-10,12H,1-2,4,7-8,11H2	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	<1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Leiden University Curated by ChEMBL					Assay Description Inhibition of full-length human DAGLalpha expressed in HEK293T cell membranes using para-nitrophenylbutyrate by colorimetric assay				J Med Chem 58: 9742-53 (2015) Article DOI: 10.1021/acs.jmedchem.5b01627 BindingDB Entry DOI: 10.7270/Q2D50QZ9
					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 (aa 30-579) (Rattus norvegicus (rat))	BDBM50204483 (7-phenyl-1-(5-(trifluoromethyl)oxazol-2-yl)heptan-...) Show SMILES FC(F)(F)c1cnc(o1)C(=O)CCCCCCc1ccccc1 Show InChI InChI=1S/C17H18F3NO2/c18-17(19,20)15-12-21-16(23-15)14(22)11-7-2-1-4-8-13-9-5-3-6-10-13/h3,5-6,9-10,12H,1-2,4,7-8,11H2	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	70	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Inhibition of rat FAAH				Bioorg Med Chem Lett 18: 5842-6 (2008) Article DOI: 10.1016/j.bmcl.2008.06.084 BindingDB Entry DOI: 10.7270/Q2DN44V8
					More data for this Ligand-Target Pair
Acyl-CoA: cholesterol acyltransferase (ACAT) (Homo sapiens (Human))	BDBM50204483 (7-phenyl-1-(5-(trifluoromethyl)oxazol-2-yl)heptan-...) Show SMILES FC(F)(F)c1cnc(o1)C(=O)CCCCCCc1ccccc1 Show InChI InChI=1S/C17H18F3NO2/c18-17(19,20)15-12-21-16(23-15)14(22)11-7-2-1-4-8-13-9-5-3-6-10-13/h3,5-6,9-10,12H,1-2,4,7-8,11H2	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Inhibition of TGH (unknown origin)				Bioorg Med Chem Lett 18: 5842-6 (2008) Article DOI: 10.1016/j.bmcl.2008.06.084 BindingDB Entry DOI: 10.7270/Q2DN44V8
					More data for this Ligand-Target Pair
Neutral cholesterol ester hydrolase 1 (Homo sapiens (Human))	BDBM50204483 (7-phenyl-1-(5-(trifluoromethyl)oxazol-2-yl)heptan-...) Show SMILES FC(F)(F)c1cnc(o1)C(=O)CCCCCCc1ccccc1 Show InChI InChI=1S/C17H18F3NO2/c18-17(19,20)15-12-21-16(23-15)14(22)11-7-2-1-4-8-13-9-5-3-6-10-13/h3,5-6,9-10,12H,1-2,4,7-8,11H2	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Inhibition of KIAA1363 (unknown origin)				Bioorg Med Chem Lett 18: 5842-6 (2008) Article DOI: 10.1016/j.bmcl.2008.06.084 BindingDB Entry DOI: 10.7270/Q2DN44V8
					More data for this Ligand-Target Pair
Acyl-CoA: cholesterol acyltransferase (ACAT) (Homo sapiens (Human))	BDBM50204483 (7-phenyl-1-(5-(trifluoromethyl)oxazol-2-yl)heptan-...) Show SMILES FC(F)(F)c1cnc(o1)C(=O)CCCCCCc1ccccc1 Show InChI InChI=1S/C17H18F3NO2/c18-17(19,20)15-12-21-16(23-15)14(22)11-7-2-1-4-8-13-9-5-3-6-10-13/h3,5-6,9-10,12H,1-2,4,7-8,11H2	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Inhibition of TGH				J Med Chem 50: 1058-68 (2007) Article DOI: 10.1021/jm0611509 BindingDB Entry DOI: 10.7270/Q26H4J6G
					More data for this Ligand-Target Pair