BindingDB PrimarySearch

null

SMILES: CC1(C)CC[C@@]2(CC[C@]3(C)C(=CC[C@@H]4[C@@]5(C)CC[C@H](O)C(C)(C)[C@@H]5CC[C@@]34C)[C@@H]2C1)C(O)=O

InChI Key: InChIKey=MIJYXULNPSFWEK-GTOFXWBISA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 130 hits for monomerid = 50346601
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Aldo-keto reductase family 1 member B10 (Homo sapiens (Human))	BDBM50346601 (NSC-114945 \| OLEANOLIC_ACID \| Oleanolic acid \| Ole...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase MCE KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	72	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Gifu Pharmaceutical University Curated by ChEMBL					Assay Description Competitive inhibition of dehydrogenase activity of N-terminal 6His-tagged human AKR1B10 expressed in Escherichia coli BL21(DE3) assessed as NADP+-li...				J Nat Prod 74: 1201-6 (2011) Article DOI: 10.1021/np200118q BindingDB Entry DOI: 10.7270/Q25D8SXZ
Gifu Pharmaceutical University Curated by ChEMBL					More data for this Ligand-Target Pair
Tyrosine-protein phosphatase non-receptor type 1 [1-405] (Homo sapiens (Human))	BDBM50346601 (NSC-114945 \| OLEANOLIC_ACID \| Oleanolic acid \| Ole...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE KEGG PC cid PC sid UniChem Patents Similars		2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details BindingDB Entry DOI: 10.7270/Q2XG9W3B
TBA					More data for this Ligand-Target Pair
Tyrosine-protein phosphatase non-receptor type 1 [1-321] (Homo sapiens (Human))	BDBM50346601 (NSC-114945 \| OLEANOLIC_ACID \| Oleanolic acid \| Ole...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE KEGG PC cid PC sid UniChem Patents Similars		4.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details BindingDB Entry DOI: 10.7270/Q2XG9W3B
TBA					More data for this Ligand-Target Pair
Tyrosine-protein phosphatase non-receptor type 1 (Homo sapiens (Human))	BDBM50346601 (NSC-114945 \| OLEANOLIC_ACID \| Oleanolic acid \| Ole...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	6.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universidad Aut£noma del estado de Morelos Curated by ChEMBL					Assay Description Mixed-type inhibition of purified human GST-tagged PTP-1B using p-nitrophenylphosphate as substrate by double-reciprocal plot method				Eur J Med Chem 87: 316-27 (2014) Article DOI: 10.1016/j.ejmech.2014.09.036 BindingDB Entry DOI: 10.7270/Q2DB83NK
					More data for this Ligand-Target Pair
Tyrosine-protein phosphatase non-receptor type 1 (Homo sapiens (Human))	BDBM50346601 (NSC-114945 \| OLEANOLIC_ACID \| Oleanolic acid \| Ole...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	6.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universidad Aut£noma del Estado de Morelos Curated by ChEMBL					Assay Description Mixed type inhibition of human recombinant PTP-1B expressed in Escherichia coli TB1 using p-nitrophenyl phosphate as substrate				Eur J Med Chem 46: 2243-51 (2011) Article DOI: 10.1016/j.ejmech.2011.03.005 BindingDB Entry DOI: 10.7270/Q2FT8N4M
					More data for this Ligand-Target Pair
Glycogen phosphorylase, muscle form (Oryctolagus cuniculus (rabbit))	BDBM50346601 (NSC-114945 \| OLEANOLIC_ACID \| Oleanolic acid \| Ole...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase MCE KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.40E+4	n/a	n/a	n/a	n/a	7.2	22
Institute of Traditional Chinese Medicine, Chengde Medical University, Chengde, 067000, China					Assay Description Rabbit muscle glycogen phosphorylase a (RMGPa) activity was measured by the release of phosphate from glucose-1-phosphate at 655 nm. Each compound wa...				Chem Biol Drug Des 83: 297-305 (2014) Article DOI: 10.1111/cbdd.12241 BindingDB Entry DOI: 10.7270/Q2TH8KBS
					More data for this Ligand-Target Pair
Tyrosine-protein phosphatase non-receptor type 1 (Homo sapiens (Human))	BDBM50346601 (NSC-114945 \| OLEANOLIC_ACID \| Oleanolic acid \| Ole...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
Jiangnan University					Assay Description IC50 values were determined by pNPP assay.				Bioorg Med Chem Lett 24: 1889-94 (2014) Article DOI: 10.1016/j.bmcl.2014.03.015 BindingDB Entry DOI: 10.7270/Q2PC3122
Jiangnan University					More data for this Ligand-Target Pair
Tyrosine-protein phosphatase non-receptor type 2 (Homo sapiens (Human))	BDBM50346601 (NSC-114945 \| OLEANOLIC_ACID \| Oleanolic acid \| Ole...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase MCE KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	4.23E+3	n/a	n/a	n/a	n/a	n/a	n/a
Jiangnan University					Assay Description IC50 values were determined by pNPP assay.				Bioorg Med Chem Lett 24: 1889-94 (2014) Article DOI: 10.1016/j.bmcl.2014.03.015 BindingDB Entry DOI: 10.7270/Q2PC3122
Jiangnan University					More data for this Ligand-Target Pair
Tyrosine-protein phosphatase non-receptor type 1 (Homo sapiens (Human))	BDBM50346601 (NSC-114945 \| OLEANOLIC_ACID \| Oleanolic acid \| Ole...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.95E+3	n/a	n/a	n/a	n/a	6.5	n/a
Jiangnan University					Assay Description Briefly, the tested compounds were solubilized in DMSO and serially diluted into concentrations for the inhibitory test. The assays were carried out ...				Chem Biol Drug Des 86: 1161-7 (2015) Article DOI: 10.1111/cbdd.12587 BindingDB Entry DOI: 10.7270/Q20C4TJ1
Jiangnan University					More data for this Ligand-Target Pair
Env polyprotein (Human immunodeficiency virus 1)	BDBM50346601 (NSC-114945 \| OLEANOLIC_ACID \| Oleanolic acid \| Ole...) Show SMILES Show InChI	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase MCE KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a
Beijing Institute of Pharmacology& Toxicology Curated by ChEMBL					Assay Description Inhibition of HIV1 gp41-induced cell-cell fusion between viral envelope expressing human HL2/3 cells to CD4/CCR5 receptor expressing TZM-bl cells aft...				J Med Chem 57: 7342-54 (2014) Article DOI: 10.1021/jm500763m BindingDB Entry DOI: 10.7270/Q2GF0W3J
					More data for this Ligand-Target Pair
Tyrosine-protein phosphatase non-receptor type 1 (Homo sapiens (Human))	BDBM50346601 (NSC-114945 \| OLEANOLIC_ACID \| Oleanolic acid \| Ole...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.03E+3	n/a	n/a	n/a	n/a	n/a	n/a
Tohoku Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of PTP1B (unknown origin)				Bioorg Med Chem Lett 25: 904-7 (2015) Article DOI: 10.1016/j.bmcl.2014.12.058 BindingDB Entry DOI: 10.7270/Q29W0H5T
Tohoku Pharmaceutical University Curated by ChEMBL					More data for this Ligand-Target Pair
Tyrosine-protein phosphatase non-receptor type 2 (Homo sapiens (Human))	BDBM50346601 (NSC-114945 \| OLEANOLIC_ACID \| Oleanolic acid \| Ole...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase MCE KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
Liaoning Normal University Curated by ChEMBL					Assay Description Inhibition of TCPTP (unknown origin)				Bioorg Med Chem Lett 24: 4125-8 (2014) Article DOI: 10.1016/j.bmcl.2014.07.055 BindingDB Entry DOI: 10.7270/Q2MP54XR
Liaoning Normal University Curated by ChEMBL					More data for this Ligand-Target Pair
Tyrosine-protein phosphatase non-receptor type 1 (Homo sapiens (Human))	BDBM50346601 (NSC-114945 \| OLEANOLIC_ACID \| Oleanolic acid \| Ole...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.86E+3	n/a	n/a	n/a	n/a	n/a	n/a
Liaoning Normal University Curated by ChEMBL					Assay Description Inhibition of PTP1B (unknown origin)				Bioorg Med Chem Lett 24: 4125-8 (2014) Article DOI: 10.1016/j.bmcl.2014.07.055 BindingDB Entry DOI: 10.7270/Q2MP54XR
Liaoning Normal University Curated by ChEMBL					More data for this Ligand-Target Pair
Tyrosine-protein phosphatase non-receptor type 1 (Homo sapiens (Human))	BDBM50346601 (NSC-114945 \| OLEANOLIC_ACID \| Oleanolic acid \| Ole...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	3.02E+3	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of PTP1B (unknown origin)				Bioorg Med Chem Lett 25: 2211-6 (2015) Article DOI: 10.1016/j.bmcl.2015.03.060 BindingDB Entry DOI: 10.7270/Q2MC91Q7
Chinese Academy of Sciences Curated by ChEMBL					More data for this Ligand-Target Pair
Tyrosine-protein phosphatase non-receptor type 1 (Homo sapiens (Human))	BDBM50346601 (NSC-114945 \| OLEANOLIC_ACID \| Oleanolic acid \| Ole...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.56E+3	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of PTP1B (unknown origin) using pNPP substrate measured after 3 mins by colorimetric assay				Bioorg Med Chem Lett 25: 2028-32 (2015) Article DOI: 10.1016/j.bmcl.2015.04.003 BindingDB Entry DOI: 10.7270/Q2XP76M3
Chinese Academy of Sciences Curated by ChEMBL					More data for this Ligand-Target Pair
Tyrosine-protein phosphatase non-receptor type 2 (Homo sapiens (Human))	BDBM50346601 (NSC-114945 \| OLEANOLIC_ACID \| Oleanolic acid \| Ole...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase MCE KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	5.46E+3	n/a	n/a	n/a	n/a	n/a	n/a
Qilu University of Technology Curated by ChEMBL					Assay Description Inhibition of TCPTP (unknown origin) assessed as pNPP hydrolysis after 30 mins				Bioorg Med Chem 23: 4891-8 (2015) Article DOI: 10.1016/j.bmc.2015.05.032 BindingDB Entry DOI: 10.7270/Q28917N0
Qilu University of Technology Curated by ChEMBL					More data for this Ligand-Target Pair
Tyrosine-protein phosphatase non-receptor type 1 (Homo sapiens (Human))	BDBM50346601 (NSC-114945 \| OLEANOLIC_ACID \| Oleanolic acid \| Ole...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.54E+3	n/a	n/a	n/a	n/a	n/a	n/a
Qilu University of Technology Curated by ChEMBL					Assay Description Inhibition of recombinant PTP1B (unknown origin) assessed as pNPP hydrolysis after 30 mins				Bioorg Med Chem 23: 4891-8 (2015) Article DOI: 10.1016/j.bmc.2015.05.032 BindingDB Entry DOI: 10.7270/Q28917N0
Qilu University of Technology Curated by ChEMBL					More data for this Ligand-Target Pair
Tyrosine-protein phosphatase non-receptor type 1 (Homo sapiens (Human))	BDBM50346601 (NSC-114945 \| OLEANOLIC_ACID \| Oleanolic acid \| Ole...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Tohoku Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of human recombinant PTP1B using pNPP as substrate assessed as rate of hydrolysis incubated for 10 mins prior to substrate addition measur...				J Nat Prod 78: 1428-33 (2015) Article DOI: 10.1021/acs.jnatprod.5b00375 BindingDB Entry DOI: 10.7270/Q2VH5QM6
Tohoku Pharmaceutical University Curated by ChEMBL					More data for this Ligand-Target Pair
Tyrosine-protein phosphatase non-receptor type 1 (Homo sapiens (Human))	BDBM50346601 (NSC-114945 \| OLEANOLIC_ACID \| Oleanolic acid \| Ole...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	9.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universidad Aut£noma del estado de Morelos Curated by ChEMBL					Assay Description Inhibition of purified human GST-tagged PTP-1B using p-nitrophenylphosphate as substrate by spectrophotometry				Eur J Med Chem 87: 316-27 (2014) Article DOI: 10.1016/j.ejmech.2014.09.036 BindingDB Entry DOI: 10.7270/Q2DB83NK
					More data for this Ligand-Target Pair
Low molecular weight phosphotyrosine protein phosphatase (Homo sapiens (Human))	BDBM50346601 (NSC-114945 \| OLEANOLIC_ACID \| Oleanolic acid \| Ole...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase MCE KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.12E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universidad Aut£noma del estado de Morelos Curated by ChEMBL					Assay Description Inhibition of human LMW-PTP IF1 using p-nitrophenylphosphate as substrate by spectrophotometry				Eur J Med Chem 87: 316-27 (2014) Article DOI: 10.1016/j.ejmech.2014.09.036 BindingDB Entry DOI: 10.7270/Q2DB83NK
					More data for this Ligand-Target Pair
Low molecular weight phosphotyrosine protein phosphatase (Homo sapiens (Human))	BDBM50346601 (NSC-114945 \| OLEANOLIC_ACID \| Oleanolic acid \| Ole...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase MCE KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.29E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universidad Aut£noma del estado de Morelos Curated by ChEMBL					Assay Description Inhibition of human LMW-PTP IF2 using p-nitrophenylphosphate as substrate by spectrophotometry				Eur J Med Chem 87: 316-27 (2014) Article DOI: 10.1016/j.ejmech.2014.09.036 BindingDB Entry DOI: 10.7270/Q2DB83NK
					More data for this Ligand-Target Pair
Tyrosine-protein phosphatase non-receptor type 1 (Homo sapiens (Human))	BDBM50346601 (NSC-114945 \| OLEANOLIC_ACID \| Oleanolic acid \| Ole...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	700	n/a	n/a	n/a	n/a	n/a	n/a
Tohoku Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of PTP1B (unknown origin)				Bioorg Med Chem Lett 25: 3087-90 (2015) Article DOI: 10.1016/j.bmcl.2015.06.026 BindingDB Entry DOI: 10.7270/Q2WW7KF5
Tohoku Pharmaceutical University Curated by ChEMBL					More data for this Ligand-Target Pair
Tyrosine-protein phosphatase non-receptor type 1 (Homo sapiens (Human))	BDBM50346601 (NSC-114945 \| OLEANOLIC_ACID \| Oleanolic acid \| Ole...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	700	n/a	n/a	n/a	n/a	n/a	n/a
Tohoku Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of PTP1B (unknown origin) pre-incubated for 10 mins before addition of p-nitrophenyl phosphate substrate and measured 30 mins post substra...				Bioorg Med Chem Lett 25: 3900-2 (2015) Article DOI: 10.1016/j.bmcl.2015.07.039 BindingDB Entry DOI: 10.7270/Q2KW5HV5
Tohoku Pharmaceutical University Curated by ChEMBL					More data for this Ligand-Target Pair
Tyrosine-protein phosphatase non-receptor type 2 (Homo sapiens (Human))	BDBM50346601 (NSC-114945 \| OLEANOLIC_ACID \| Oleanolic acid \| Ole...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase MCE KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	5.46E+3	n/a	n/a	n/a	n/a	n/a	n/a
Qilu University of Technology Curated by ChEMBL					Assay Description Inhibition of TCPTP (unknown origin) assessed as hydrolysis of pNPP to pNP after 30 mins				Bioorg Med Chem 23: 7079-88 (2015) Article DOI: 10.1016/j.bmc.2015.09.024 BindingDB Entry DOI: 10.7270/Q2QZ2CTV
Qilu University of Technology Curated by ChEMBL					More data for this Ligand-Target Pair
Tyrosine-protein phosphatase non-receptor type 1 (Homo sapiens (Human))	BDBM50346601 (NSC-114945 \| OLEANOLIC_ACID \| Oleanolic acid \| Ole...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.54E+3	n/a	n/a	n/a	n/a	n/a	n/a
Qilu University of Technology Curated by ChEMBL					Assay Description Inhibition of recombinant PTP1B (unknown origin) assessed as hydrolysis of pNPP to pNP after 30 mins				Bioorg Med Chem 23: 7079-88 (2015) Article DOI: 10.1016/j.bmc.2015.09.024 BindingDB Entry DOI: 10.7270/Q2QZ2CTV
Qilu University of Technology Curated by ChEMBL					More data for this Ligand-Target Pair
Tyrosine-protein phosphatase non-receptor type 1 (Homo sapiens (Human))	BDBM50346601 (NSC-114945 \| OLEANOLIC_ACID \| Oleanolic acid \| Ole...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	730	n/a	n/a	n/a	n/a	n/a	n/a
Tohoku Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of recombinant human PTP1B using pNPP as substrate incubated for 10 mins prior to substrate addition measured after 30 mins by microplate ...				Bioorg Med Chem Lett 26: 315-7 (2016) Article DOI: 10.1016/j.bmcl.2015.12.022 BindingDB Entry DOI: 10.7270/Q2SF2Z0K
Tohoku Pharmaceutical University Curated by ChEMBL					More data for this Ligand-Target Pair
Tyrosine-protein phosphatase non-receptor type 1 (Homo sapiens (Human))	BDBM50346601 (NSC-114945 \| OLEANOLIC_ACID \| Oleanolic acid \| Ole...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	3.02E+3	n/a	n/a	n/a	n/a	n/a	n/a
Shanghai Institute of Materia Medica Curated by ChEMBL					Assay Description Inhibition of recombinant human PTP1B catalytic domain assessed as hydrolysis of pNPP after 2 mins				Bioorg Med Chem Lett 26: 778-81 (2016) Article DOI: 10.1016/j.bmcl.2015.12.097 BindingDB Entry DOI: 10.7270/Q2K939CS
Shanghai Institute of Materia Medica Curated by ChEMBL					More data for this Ligand-Target Pair
Tyrosine-protein phosphatase non-receptor type 6 (Homo sapiens (Human))	BDBM50346601 (NSC-114945 \| OLEANOLIC_ACID \| Oleanolic acid \| Ole...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase MCE KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>1.20E+5	n/a	n/a	n/a	n/a	n/a	n/a
Shanghai Institute of Materia Medica Curated by ChEMBL					Assay Description Inhibition of human SHP1 as hydrolysis of pNPP after 2 mins				Bioorg Med Chem Lett 26: 778-81 (2016) Article DOI: 10.1016/j.bmcl.2015.12.097 BindingDB Entry DOI: 10.7270/Q2K939CS
Shanghai Institute of Materia Medica Curated by ChEMBL					More data for this Ligand-Target Pair
Tyrosine-protein phosphatase non-receptor type 11 (Homo sapiens (Human))	BDBM50346601 (NSC-114945 \| OLEANOLIC_ACID \| Oleanolic acid \| Ole...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>1.20E+5	n/a	n/a	n/a	n/a	n/a	n/a
Shanghai Institute of Materia Medica Curated by ChEMBL					Assay Description Inhibition of human SHP2 as hydrolysis of pNPP after 2 mins				Bioorg Med Chem Lett 26: 778-81 (2016) Article DOI: 10.1016/j.bmcl.2015.12.097 BindingDB Entry DOI: 10.7270/Q2K939CS
Shanghai Institute of Materia Medica Curated by ChEMBL					More data for this Ligand-Target Pair
Tyrosine-protein phosphatase non-receptor type 2 (Homo sapiens (Human))	BDBM50346601 (NSC-114945 \| OLEANOLIC_ACID \| Oleanolic acid \| Ole...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase MCE KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>1.20E+5	n/a	n/a	n/a	n/a	n/a	n/a
Shanghai Institute of Materia Medica Curated by ChEMBL					Assay Description Inhibition of human TCPTP as hydrolysis of pNPP after 2 mins				Bioorg Med Chem Lett 26: 778-81 (2016) Article DOI: 10.1016/j.bmcl.2015.12.097 BindingDB Entry DOI: 10.7270/Q2K939CS
Shanghai Institute of Materia Medica Curated by ChEMBL					More data for this Ligand-Target Pair
Receptor-type tyrosine-protein phosphatase F (Homo sapiens (Human))	BDBM50346601 (NSC-114945 \| OLEANOLIC_ACID \| Oleanolic acid \| Ole...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase MCE KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>1.20E+5	n/a	n/a	n/a	n/a	n/a	n/a
Shanghai Institute of Materia Medica Curated by ChEMBL					Assay Description Inhibition of human LAR as hydrolysis of pNPP after 2 mins				Bioorg Med Chem Lett 26: 778-81 (2016) Article DOI: 10.1016/j.bmcl.2015.12.097 BindingDB Entry DOI: 10.7270/Q2K939CS
Shanghai Institute of Materia Medica Curated by ChEMBL					More data for this Ligand-Target Pair
Tyrosine-protein phosphatase non-receptor type 1 (Homo sapiens (Human))	BDBM50346601 (NSC-114945 \| OLEANOLIC_ACID \| Oleanolic acid \| Ole...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.54E+3	n/a	n/a	n/a	n/a	n/a	n/a
Qilu University of Technology Curated by ChEMBL					Assay Description Inhibition of recombinant PTP1B (unknown origin) using pNPP as substrate incubated for 30 mins				Eur J Med Chem 118: 27-33 (2016) Article DOI: 10.1016/j.ejmech.2016.04.014 BindingDB Entry DOI: 10.7270/Q2JS9SCC
Qilu University of Technology Curated by ChEMBL					More data for this Ligand-Target Pair
Tyrosine-protein phosphatase non-receptor type 2 (Homo sapiens (Human))	BDBM50346601 (NSC-114945 \| OLEANOLIC_ACID \| Oleanolic acid \| Ole...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase MCE KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	5.46E+3	n/a	n/a	n/a	n/a	n/a	n/a
Qilu University of Technology Curated by ChEMBL					Assay Description Inhibition of human TCPTP using pNPP as substrate incubated for 30 mins				Eur J Med Chem 118: 27-33 (2016) Article DOI: 10.1016/j.ejmech.2016.04.014 BindingDB Entry DOI: 10.7270/Q2JS9SCC
Qilu University of Technology Curated by ChEMBL					More data for this Ligand-Target Pair
Tyrosine-protein phosphatase non-receptor type 6 (Homo sapiens (Human))	BDBM50346601 (NSC-114945 \| OLEANOLIC_ACID \| Oleanolic acid \| Ole...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase MCE KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.42E+4	n/a	n/a	n/a	n/a	n/a	n/a
Qilu University of Technology Curated by ChEMBL					Assay Description Inhibition of human SHP1 using pNPP as substrate incubated for 30 mins				Eur J Med Chem 118: 27-33 (2016) Article DOI: 10.1016/j.ejmech.2016.04.014 BindingDB Entry DOI: 10.7270/Q2JS9SCC
Qilu University of Technology Curated by ChEMBL					More data for this Ligand-Target Pair
Tyrosine-protein phosphatase non-receptor type 11 (Homo sapiens (Human))	BDBM50346601 (NSC-114945 \| OLEANOLIC_ACID \| Oleanolic acid \| Ole...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.16E+4	n/a	n/a	n/a	n/a	n/a	n/a
Qilu University of Technology Curated by ChEMBL					Assay Description Inhibition of human SHP2 using pNPP as substrate incubated for 30 mins				Eur J Med Chem 118: 27-33 (2016) Article DOI: 10.1016/j.ejmech.2016.04.014 BindingDB Entry DOI: 10.7270/Q2JS9SCC
Qilu University of Technology Curated by ChEMBL					More data for this Ligand-Target Pair
Receptor-type tyrosine-protein phosphatase F (Homo sapiens (Human))	BDBM50346601 (NSC-114945 \| OLEANOLIC_ACID \| Oleanolic acid \| Ole...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase MCE KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.23E+4	n/a	n/a	n/a	n/a	n/a	n/a
Qilu University of Technology Curated by ChEMBL					Assay Description Inhibition of human LAR using pNPP as substrate incubated for 30 mins				Eur J Med Chem 118: 27-33 (2016) Article DOI: 10.1016/j.ejmech.2016.04.014 BindingDB Entry DOI: 10.7270/Q2JS9SCC
Qilu University of Technology Curated by ChEMBL					More data for this Ligand-Target Pair
Glycogen phosphorylase, muscle form (Oryctolagus cuniculus (rabbit))	BDBM50346601 (NSC-114945 \| OLEANOLIC_ACID \| Oleanolic acid \| Ole...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase MCE KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.40E+4	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of rabbit muscle glycogen phosphorylase A assessed as release of phosphate from glucose-1-phosphate after 25 mins by microplate reader bas...				Eur J Med Chem 46: 2011-21 (2011) Article DOI: 10.1016/j.ejmech.2011.02.053 BindingDB Entry DOI: 10.7270/Q2DB826B
Chinese Academy of Sciences Curated by ChEMBL					More data for this Ligand-Target Pair
Tyrosine-protein phosphatase non-receptor type 1 (Homo sapiens (Human))	BDBM50346601 (NSC-114945 \| OLEANOLIC_ACID \| Oleanolic acid \| Ole...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	3.84E+3	n/a	n/a	n/a	n/a	n/a	n/a
State Key Laboratory of Bioactive Substance and Function of Natural Medicines, and Key Laboratory of Bioactive Substances and Resources Utilization of Chinese Herbal Medicine Curated by ChEMBL					Assay Description Inhibition of GST-tagged human recombinant PTP1B assessed as dephosphorylation of para-nitrophenyl phosphate after 10 mins by spectrophotometric anal...				J Nat Prod 74: 2431-7 (2011) Article DOI: 10.1021/np200706n BindingDB Entry DOI: 10.7270/Q2ZS2WZ9
					More data for this Ligand-Target Pair
Glycogen phosphorylase, muscle form (Oryctolagus cuniculus (rabbit))	BDBM50346601 (NSC-114945 \| OLEANOLIC_ACID \| Oleanolic acid \| Ole...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase MCE KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.29E+4	n/a	n/a	n/a	n/a	n/a	n/a
China Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of rabbit muscle glycogen phosphorylase a assessed as release of phosphate from glucose-1-phosphate after 25 mins using malachite green st...				Bioorg Med Chem Lett 22: 1036-9 (2012) Article DOI: 10.1016/j.bmcl.2011.11.123 BindingDB Entry DOI: 10.7270/Q21J9B74
China Pharmaceutical University Curated by ChEMBL					More data for this Ligand-Target Pair
Tyrosine-protein phosphatase non-receptor type 1 (Homo sapiens (Human))	BDBM50346601 (NSC-114945 \| OLEANOLIC_ACID \| Oleanolic acid \| Ole...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	3.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
Korea Research Institute of Bioscience and Biotechnology Curated by ChEMBL					Assay Description Inhibition of human recombinant PTP1B				Bioorg Med Chem Lett 16: 3273-6 (2006) Article DOI: 10.1016/j.bmcl.2006.03.036 BindingDB Entry DOI: 10.7270/Q2ZP46WV
					More data for this Ligand-Target Pair
Nitric oxide synthase, inducible (Homo sapiens (Human))	BDBM50346601 (NSC-114945 \| OLEANOLIC_ACID \| Oleanolic acid \| Ole...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>4.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Dartmouth College Curated by ChEMBL					Assay Description Inhibition of inducible nitric oxide synthase in activated macrophages				Bioorg Med Chem Lett 15: 2215-9 (2005) Article DOI: 10.1016/j.bmcl.2005.03.031 BindingDB Entry DOI: 10.7270/Q23N245R
Dartmouth College Curated by ChEMBL					More data for this Ligand-Target Pair
Phospholipase A2 (Homo sapiens (Human))	BDBM50346601 (NSC-114945 \| OLEANOLIC_ACID \| Oleanolic acid \| Ole...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Gifu Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of phospholipase A2				J Nat Prod 74: 1201-6 (2011) Article DOI: 10.1021/np200118q BindingDB Entry DOI: 10.7270/Q25D8SXZ
Gifu Pharmaceutical University Curated by ChEMBL					More data for this Ligand-Target Pair
DNA polymerase beta (Homo sapiens (Human))	BDBM50346601 (NSC-114945 \| OLEANOLIC_ACID \| Oleanolic acid \| Ole...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Gifu Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of DNA polymerase beta				J Nat Prod 74: 1201-6 (2011) Article DOI: 10.1021/np200118q BindingDB Entry DOI: 10.7270/Q25D8SXZ
Gifu Pharmaceutical University Curated by ChEMBL					More data for this Ligand-Target Pair
Aldo-keto reductase family 1 member B10 (Homo sapiens (Human))	BDBM50346601 (NSC-114945 \| OLEANOLIC_ACID \| Oleanolic acid \| Ole...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase MCE KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	4.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Gifu Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of N-terminal 6His-tagged human AKR1B10 overexpressed in human HeLa cells assessed as inhibition of [1-14C]farnesol reduction pretreated f...				J Nat Prod 74: 1201-6 (2011) Article DOI: 10.1021/np200118q BindingDB Entry DOI: 10.7270/Q25D8SXZ
Gifu Pharmaceutical University Curated by ChEMBL					More data for this Ligand-Target Pair
Aldo-keto reductase family 1 member B1 (Homo sapiens (Human))	BDBM50346601 (NSC-114945 \| OLEANOLIC_ACID \| Oleanolic acid \| Ole...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase MCE KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.24E+5	n/a	n/a	n/a	n/a	n/a	n/a
Gifu Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of reductase activity of N-terminal 6His-tagged human recombinant AKR1B1 expressed in Escherichia coli BL21(DE3) assessed as assessed as p...				J Nat Prod 74: 1201-6 (2011) Article DOI: 10.1021/np200118q BindingDB Entry DOI: 10.7270/Q25D8SXZ
Gifu Pharmaceutical University Curated by ChEMBL					More data for this Ligand-Target Pair
Aldo-keto reductase family 1 member B10 (Homo sapiens (Human))	BDBM50346601 (NSC-114945 \| OLEANOLIC_ACID \| Oleanolic acid \| Ole...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase MCE KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	90	n/a	n/a	n/a	n/a	n/a	n/a
Gifu Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of reductase activity of N-terminal 6His-tagged human AKR1B10 expressed in Escherichia coli BL21(DE3) assessed as pyridine-3-aldehyde redu...				J Nat Prod 74: 1201-6 (2011) Article DOI: 10.1021/np200118q BindingDB Entry DOI: 10.7270/Q25D8SXZ
Gifu Pharmaceutical University Curated by ChEMBL					More data for this Ligand-Target Pair
Glycogen phosphorylase, muscle form (Oryctolagus cuniculus (rabbit))	BDBM50346601 (NSC-114945 \| OLEANOLIC_ACID \| Oleanolic acid \| Ole...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase MCE KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.40E+4	n/a	n/a	n/a	n/a	n/a	n/a
China Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of rabbit muscle GPa				Bioorg Med Chem Lett 16: 2915-9 (2006) Article DOI: 10.1016/j.bmcl.2006.03.009 BindingDB Entry DOI: 10.7270/Q2571CT8
China Pharmaceutical University Curated by ChEMBL					More data for this Ligand-Target Pair
Tyrosine-protein phosphatase non-receptor type 1 (Homo sapiens (Human))	BDBM50346601 (NSC-114945 \| OLEANOLIC_ACID \| Oleanolic acid \| Ole...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.01E+3	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of GST-tagged PTP1B (unknown origin) using pNPP as substrate measured for 2 mins by colorimetric analysis				Eur J Med Chem 69: 399-412 (2013) Article DOI: 10.1016/j.ejmech.2013.09.017 BindingDB Entry DOI: 10.7270/Q2VM4DP1
Chinese Academy of Sciences Curated by ChEMBL					More data for this Ligand-Target Pair
Tyrosine-protein phosphatase non-receptor type 1 (Homo sapiens (Human))	BDBM50346601 (NSC-114945 \| OLEANOLIC_ACID \| Oleanolic acid \| Ole...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	3.02E+3	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of PTP1B (unknown origin)				Bioorg Med Chem Lett 23: 5061-5 (2013) Article DOI: 10.1016/j.bmcl.2013.07.039 BindingDB Entry DOI: 10.7270/Q2Z60QHS
Chinese Academy of Sciences Curated by ChEMBL					More data for this Ligand-Target Pair
Tyrosine-protein phosphatase non-receptor type 1 (Homo sapiens (Human))	BDBM50346601 (NSC-114945 \| OLEANOLIC_ACID \| Oleanolic acid \| Ole...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Tohoku Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of PTP1B (unknown origin)				Bioorg Med Chem Lett 23: 2151-4 (2013) Article DOI: 10.1016/j.bmcl.2013.01.102 BindingDB Entry DOI: 10.7270/Q2Q81FFG
Tohoku Pharmaceutical University Curated by ChEMBL					More data for this Ligand-Target Pair

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