BDBM65175 1-[(2,4-dichlorobenzoyl)amino]-3-[3-(trifluoromethyl)phenyl]thiourea::1-[(2,4-dichlorophenyl)carbonylamino]-3-[3-(trifluoromethyl)phenyl]thiourea::1-[[(2,4-dichlorophenyl)-oxomethyl]amino]-3-[3-(trifluoromethyl)phenyl]thiourea::MLS000588859::SMR000212491::cid_3729816

SMILES: FC(F)(F)c1cccc(NC(=S)NNC(=O)c2ccc(Cl)cc2Cl)c1

InChI Key: InChIKey=QURGAZDGMITPFZ-UHFFFAOYSA-N

Data: 2 IC50  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 65175   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
TPA: Essential protein of the mitochondrial intermembrane space (Saccharomyces cerevisiae S288c)	BDBM65175 (1-[(2,4-dichlorobenzoyl)amino]-3-[3-(trifluorometh...) Show SMILES FC(F)(F)c1cccc(NC(=S)NNC(=O)c2ccc(Cl)cc2Cl)c1 Show InChI InChI=1S/C15H10Cl2F3N3OS/c16-9-4-5-11(12(17)7-9)13(24)22-23-14(25)21-10-3-1-2-8(6-10)15(18,19)20/h1-7H,(H,22,24)(H2,21,23,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	8.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Burnham Center for Chemical Genomics Curated by PubChem BioAssay					Assay Description Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute(SBMRI, San Diego, CA...				PubChem Bioassay (2010) BindingDB Entry DOI: 10.7270/Q2F18X6W
					More data for this Ligand-Target Pair
corticotropin releasing factor-binding protein (Homo sapiens (Human))	BDBM65175 (1-[(2,4-dichlorobenzoyl)amino]-3-[3-(trifluorometh...) Show SMILES FC(F)(F)c1cccc(NC(=S)NNC(=O)c2ccc(Cl)cc2Cl)c1 Show InChI InChI=1S/C15H10Cl2F3N3OS/c16-9-4-5-11(12(17)7-9)13(24)22-23-14(25)21-10-3-1-2-8(6-10)15(18,19)20/h1-7H,(H,22,24)(H2,21,23,25)	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	n/a	n/a	>5.30E+4	n/a	n/a	n/a	n/a
Burnham Center for Chemical Genomics Curated by PubChem BioAssay					Assay Description Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...				PubChem Bioassay (2012) BindingDB Entry DOI: 10.7270/Q2VX0F3D
					More data for this Ligand-Target Pair
TPA: Essential component of the Translocase of the Inner Mitochondrial membrane (TIM23 complex) (Saccharomyces cerevisiae S288c)	BDBM65175 (1-[(2,4-dichlorobenzoyl)amino]-3-[3-(trifluorometh...) Show SMILES FC(F)(F)c1cccc(NC(=S)NNC(=O)c2ccc(Cl)cc2Cl)c1 Show InChI InChI=1S/C15H10Cl2F3N3OS/c16-9-4-5-11(12(17)7-9)13(24)22-23-14(25)21-10-3-1-2-8(6-10)15(18,19)20/h1-7H,(H,22,24)(H2,21,23,25)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	7.04E+3	n/a	n/a	n/a	n/a	n/a	n/a
Burnham Center for Chemical Genomics Curated by PubChem BioAssay					Assay Description Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute(SBMRI, San Diego, CA...				PubChem Bioassay (2011) BindingDB Entry DOI: 10.7270/Q26D5RGW
					More data for this Ligand-Target Pair