Compile Data Set for Download or QSAR

Found 150 hits with Last Name = 'basha' and Initial = 'a'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Polyunsaturated fatty acid 5-lipoxygenase (Homo sapiens (Human))	BDBM50369069 (CHEMBL1907933) Show SMILES C[C@@H](C#Cc1ccc(Oc2ccc(F)cc2)o1)N(O)C(N)=O |r| Show InChI InChI=1S/C15H13FN2O4/c1-10(18(20)15(17)19)2-5-12-8-9-14(21-12)22-13-6-3-11(16)4-7-13/h3-4,6-10,20H,1H3,(H2,17,19)/t10-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description 5-lipoxygenase Inhibitory activity was measured by enzyme immunoassay using human whole blood stimulated with calcium ionophore (A23187) and LTB4 (le...				J Med Chem 38: 4768-75 (1996) BindingDB Entry DOI: 10.7270/Q2V40VV9
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Homo sapiens (Human))	BDBM50029778 (CHEMBL264717 | N-{3-[5-(4-fluorophenoxy)-2-furyl]p...) Show SMILES NC(=O)N(O)CC#Cc1ccc(Oc2ccc(F)cc2)o1 Show InChI InChI=1S/C14H11FN2O4/c15-10-3-5-12(6-4-10)21-13-8-7-11(20-13)2-1-9-17(19)14(16)18/h3-8,19H,9H2,(H2,16,18)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	60	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description 5-lipoxygenase Inhibitory activity was measured by enzyme immunoassay using human whole blood stimulated with calcium ionophore (A23187) and LTB4 (le...				J Med Chem 38: 4768-75 (1996) BindingDB Entry DOI: 10.7270/Q2V40VV9
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Homo sapiens (Human))	BDBM50029776 (CHEMBL359455 | N-{3-[5-(4-fluorobenzyl)thien-2-yl]...) Show SMILES NC(=O)N(O)CC#Cc1ccc(Cc2ccc(F)cc2)s1 Show InChI InChI=1S/C15H13FN2O2S/c16-12-5-3-11(4-6-12)10-14-8-7-13(21-14)2-1-9-18(20)15(17)19/h3-8,20H,9-10H2,(H2,17,19)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	70	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description 5-lipoxygenase Inhibitory activity was measured by enzyme immunoassay using human whole blood stimulated with calcium ionophore (A23187) and LTB4 (l...				J Med Chem 38: 4768-75 (1996) BindingDB Entry DOI: 10.7270/Q2V40VV9
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Homo sapiens (Human))	BDBM50369068 (A-79175 | CHEMBL90552) Show SMILES C[C@H](C#Cc1ccc(Oc2ccc(F)cc2)o1)N(O)C(N)=O Show InChI InChI=1S/C15H13FN2O4/c1-10(18(20)15(17)19)2-5-12-8-9-14(21-12)22-13-6-3-11(16)4-7-13/h3-4,6-10,20H,1H3,(H2,17,19)/t10-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	80	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description 5-lipoxygenase Inhibitory activity was measured by enzyme immunoassay using human whole blood stimulated with calcium ionophore (A23187) and LTB4 (le...				J Med Chem 38: 4768-75 (1996) BindingDB Entry DOI: 10.7270/Q2V40VV9
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Homo sapiens (Human))	BDBM50029775 ((R)-(+)-N-{3-[5-(4-fluorophenoxy)furan-2-yl]-1-met...) Show SMILES CC(C#Cc1ccc(Oc2ccc(F)cc2)o1)N(O)C(N)=O Show InChI InChI=1S/C15H13FN2O4/c1-10(18(20)15(17)19)2-5-12-8-9-14(21-12)22-13-6-3-11(16)4-7-13/h3-4,6-10,20H,1H3,(H2,17,19)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	80	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description 5-lipoxygenase Inhibitory activity was measured by enzyme immunoassay using human whole blood stimulated with calcium ionophore (A23187) and LTB4 (le...				J Med Chem 38: 4768-75 (1996) BindingDB Entry DOI: 10.7270/Q2V40VV9
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid lipoxygenase ALOX12 (Homo sapiens (Human))	BDBM50009004 ((phenidone)1-Phenyl-pyrazolidin-3-one | 1-Phenyl-p...) Show SMILES O=C1CCN(N1)c1ccccc1 Show InChI InChI=1S/C9H10N2O/c12-9-6-7-11(10-9)8-4-2-1-3-5-8/h1-5H,6-7H2,(H,10,12)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Compound was tested in vitro for inhibition of 12-LO human platelet				J Med Chem 39: 3938-50 (1996) Article DOI: 10.1021/jm960372b BindingDB Entry DOI: 10.7270/Q2GQ6WWW
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Homo sapiens (Human))	BDBM50029780 (CHEMBL145318 | N-{(2Z)-3-[5-(4-fluorophenoxy)furan...) Show SMILES CC(\C=C/c1ccc(Oc2ccc(F)cc2)o1)N(O)C(N)=O Show InChI InChI=1S/C15H15FN2O4/c1-10(18(20)15(17)19)2-5-12-8-9-14(21-12)22-13-6-3-11(16)4-7-13/h2-10,20H,1H3,(H2,17,19)/b5-2-	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	160	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description 5-lipoxygenase Inhibitory activity was measured by enzyme immunoassay using human whole blood stimulated with calcium ionophore (A23187) and LTB4 (le...				J Med Chem 38: 4768-75 (1996) BindingDB Entry DOI: 10.7270/Q2V40VV9
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Homo sapiens (Human))	BDBM50029781 ((R)-(+)-N-{3-[5-(4-fluorobenzyl)thien-2-yl]-1-meth...) Show SMILES C[C@H](C#Cc1ccc(Cc2ccc(F)cc2)s1)N(O)C(N)=O Show InChI InChI=1S/C16H15FN2O2S/c1-11(19(21)16(18)20)2-7-14-8-9-15(22-14)10-12-3-5-13(17)6-4-12/h3-6,8-9,11,21H,10H2,1H3,(H2,18,20)/t11-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	160	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description 5-lipoxygenase Inhibitory activity was measured by enzyme immunoassay using human whole blood stimulated with calcium ionophore (A23187) and LTB4 (le...				J Med Chem 38: 4768-75 (1996) BindingDB Entry DOI: 10.7270/Q2V40VV9
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Homo sapiens (Human))	BDBM50029779 (CHEMBL144028 | N-{3-[5-(4-fluorobenzyl)thien-2-yl]...) Show SMILES CC(C#Cc1ccc(Cc2ccc(F)cc2)s1)N(O)C(N)=O Show InChI InChI=1S/C16H15FN2O2S/c1-11(19(21)16(18)20)2-7-14-8-9-15(22-14)10-12-3-5-13(17)6-4-12/h3-6,8-9,11,21H,10H2,1H3,(H2,18,20)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description 5-lipoxygenase Inhibitory activity was measured by enzyme immunoassay using human whole blood stimulated with calcium ionophore (A23187) and LTB4 (le...				J Med Chem 38: 4768-75 (1996) BindingDB Entry DOI: 10.7270/Q2V40VV9
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Homo sapiens (Human))	BDBM50053509 (1-(3-Benzyloxy-phenyl)-[1,2,4]triazinan-3-one | CH...) Show SMILES O=C1NCCN(N1)c1cccc(OCc2ccccc2)c1 Show InChI InChI=1S/C16H17N3O2/c20-16-17-9-10-19(18-16)14-7-4-8-15(11-14)21-12-13-5-2-1-3-6-13/h1-8,11H,9-10,12H2,(H2,17,18,20)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description In vitro 5-lipoxygenase inhibitory activity against calcium ionophore (A23187) induced LTB4 formation in human polymorphonuclear leukocytes.				J Med Chem 39: 3938-50 (1996) Article DOI: 10.1021/jm960372b BindingDB Entry DOI: 10.7270/Q2GQ6WWW
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Homo sapiens (Human))	BDBM50029777 ((S)-(-)-N-{3-[5-(4-fluorobenzyl)thien-2-yl]-1-meth...) Show SMILES C[C@@H](C#Cc1ccc(Cc2ccc(F)cc2)s1)N(O)C(N)=O Show InChI InChI=1S/C16H15FN2O2S/c1-11(19(21)16(18)20)2-7-14-8-9-15(22-14)10-12-3-5-13(17)6-4-12/h3-6,8-9,11,21H,10H2,1H3,(H2,18,20)/t11-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	PubMed	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description 5-lipoxygenase Inhibitory activity was measured by enzyme immunoassay using human whole blood stimulated with calcium ionophore (A23187) and LTB4 (le...				J Med Chem 38: 4768-75 (1996) BindingDB Entry DOI: 10.7270/Q2V40VV9
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Homo sapiens (Human))	BDBM50009004 ((phenidone)1-Phenyl-pyrazolidin-3-one | 1-Phenyl-p...) Show SMILES O=C1CCN(N1)c1ccccc1 Show InChI InChI=1S/C9H10N2O/c12-9-6-7-11(10-9)8-4-2-1-3-5-8/h1-5H,6-7H2,(H,10,12)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description In vitro 5-lipoxygenase inhibitory activity of the compound against calcium ionophore (A23187) induced LTB4 formation in human whole blood				J Med Chem 39: 3938-50 (1996) Article DOI: 10.1021/jm960372b BindingDB Entry DOI: 10.7270/Q2GQ6WWW
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid lipoxygenase ALOX15 (Homo sapiens (Human))	BDBM50009004 ((phenidone)1-Phenyl-pyrazolidin-3-one | 1-Phenyl-p...) Show SMILES O=C1CCN(N1)c1ccccc1 Show InChI InChI=1S/C9H10N2O/c12-9-6-7-11(10-9)8-4-2-1-3-5-8/h1-5H,6-7H2,(H,10,12)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	420	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Compound was tested in vitro for inhibition of 15-lipoxygenase soyabean				J Med Chem 39: 3938-50 (1996) Article DOI: 10.1021/jm960372b BindingDB Entry DOI: 10.7270/Q2GQ6WWW
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus)	BDBM50009004 ((phenidone)1-Phenyl-pyrazolidin-3-one | 1-Phenyl-p...) Show SMILES O=C1CCN(N1)c1ccccc1 Show InChI InChI=1S/C9H10N2O/c12-9-6-7-11(10-9)8-4-2-1-3-5-8/h1-5H,6-7H2,(H,10,12)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	520	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description In vitro 5-lipoxygenase inhibitory activity of the compound against calcium ionophore (A23187) induced LTB4 formation in rat polymorphonuclear leukoc...				J Med Chem 39: 3938-50 (1996) Article DOI: 10.1021/jm960372b BindingDB Entry DOI: 10.7270/Q2GQ6WWW
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Homo sapiens (Human))	BDBM50009941 (1-Phenyl-tetrahydro-pyridazin-3-one | CHEMBL30110) Show SMILES O=C1CCCN(N1)c1ccccc1 Show InChI InChI=1S/C10H12N2O/c13-10-7-4-8-12(11-10)9-5-2-1-3-6-9/h1-3,5-6H,4,7-8H2,(H,11,13)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	700	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description In vitro 5-lipoxygenase inhibitory activity of the compound against calcium ionophore (A23187) induced LTB4 formation in human whole blood				J Med Chem 39: 3938-50 (1996) Article DOI: 10.1021/jm960372b BindingDB Entry DOI: 10.7270/Q2GQ6WWW
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Homo sapiens (Human))	BDBM50280197 (1-(3-Chloro-phenyl)-pyrazolidin-3-one | CHEMBL3024...) Show SMILES Clc1cccc(c1)N1CCC(=O)N1 Show InChI InChI=1S/C9H9ClN2O/c10-7-2-1-3-8(6-7)12-5-4-9(13)11-12/h1-3,6H,4-5H2,(H,11,13)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article	n/a	n/a	730	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibitory activity against 5-lipoxygenase.				Bioorg Med Chem Lett 2: 1357-1360 (1992) Article DOI: 10.1016/S0960-894X(00)80512-0 BindingDB Entry DOI: 10.7270/Q2CC10M8
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Homo sapiens (Human))	BDBM50000541 ((+-)-1-(1-Benzo[b]thien-2-ylethyl)-1-hydroxyurea |...) Show SMILES CC(N(O)C(N)=O)c1cc2ccccc2s1 Show InChI InChI=1S/C11H12N2O2S/c1-7(13(15)11(12)14)10-6-8-4-2-3-5-9(8)16-10/h2-7,15H,1H3,(H2,12,14)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE PC cid PC sid UniChem Patents Similars	DrugBank PubMed	n/a	n/a	740	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description 5-lipoxygenase Inhibitory activity was measured by enzyme immunoassay using human whole blood stimulated with calcium ionophore (A23187) and LTB4 (le...				J Med Chem 38: 4768-75 (1996) BindingDB Entry DOI: 10.7270/Q2V40VV9
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Homo sapiens (Human))	BDBM50009941 (1-Phenyl-tetrahydro-pyridazin-3-one | CHEMBL30110) Show SMILES O=C1CCCN(N1)c1ccccc1 Show InChI InChI=1S/C10H12N2O/c13-10-7-4-8-12(11-10)9-5-2-1-3-6-9/h1-3,5-6H,4,7-8H2,(H,11,13)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description In vitro 5-lipoxygenase inhibitory activity against calcium ionophore (A23187) induced LTB4 formation in human polymorphonuclear leukocytes.				J Med Chem 39: 3938-50 (1996) Article DOI: 10.1021/jm960372b BindingDB Entry DOI: 10.7270/Q2GQ6WWW
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus)	BDBM50053509 (1-(3-Benzyloxy-phenyl)-[1,2,4]triazinan-3-one | CH...) Show SMILES O=C1NCCN(N1)c1cccc(OCc2ccccc2)c1 Show InChI InChI=1S/C16H17N3O2/c20-16-17-9-10-19(18-16)14-7-4-8-15(11-14)21-12-13-5-2-1-3-6-13/h1-8,11H,9-10,12H2,(H2,17,18,20)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	1.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of 5-lipoxygenase catalysis in rat basophilic leukemia (RBL) cells by measuring 5-HETE product formation				J Med Chem 39: 3938-50 (1996) Article DOI: 10.1021/jm960372b BindingDB Entry DOI: 10.7270/Q2GQ6WWW
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Homo sapiens (Human))	BDBM50280185 (1-(4-Chloro-phenyl)-pyrazolidin-3-one | CHEMBL2960...) Show SMILES Clc1ccc(cc1)N1CCC(=O)N1 Show InChI InChI=1S/C9H9ClN2O/c10-7-1-3-8(4-2-7)12-6-5-9(13)11-12/h1-4H,5-6H2,(H,11,13)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article	n/a	n/a	1.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibitory activity against 5-lipoxygenase.				Bioorg Med Chem Lett 2: 1357-1360 (1992) Article DOI: 10.1016/S0960-894X(00)80512-0 BindingDB Entry DOI: 10.7270/Q2CC10M8
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus)	BDBM50009941 (1-Phenyl-tetrahydro-pyridazin-3-one | CHEMBL30110) Show SMILES O=C1CCCN(N1)c1ccccc1 Show InChI InChI=1S/C10H12N2O/c13-10-7-4-8-12(11-10)9-5-2-1-3-6-9/h1-3,5-6H,4,7-8H2,(H,11,13)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description In vitro 5-lipoxygenase inhibitory activity of the compound against calcium ionophore (A23187) induced LTB4 formation in rat polymorphonuclear leukoc...				J Med Chem 39: 3938-50 (1996) Article DOI: 10.1021/jm960372b BindingDB Entry DOI: 10.7270/Q2GQ6WWW
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Homo sapiens (Human))	BDBM50280192 (1-m-Tolyl-pyrazolidin-3-one | CHEMBL26084) Show SMILES Cc1cccc(c1)N1CCC(=O)N1 Show InChI InChI=1S/C10H12N2O/c1-8-3-2-4-9(7-8)12-6-5-10(13)11-12/h2-4,7H,5-6H2,1H3,(H,11,13)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article	n/a	n/a	1.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibitory activity against 5-lipoxygenase.				Bioorg Med Chem Lett 2: 1357-1360 (1992) Article DOI: 10.1016/S0960-894X(00)80512-0 BindingDB Entry DOI: 10.7270/Q2CC10M8
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Homo sapiens (Human))	BDBM50009004 ((phenidone)1-Phenyl-pyrazolidin-3-one | 1-Phenyl-p...) Show SMILES O=C1CCN(N1)c1ccccc1 Show InChI InChI=1S/C9H10N2O/c12-9-6-7-11(10-9)8-4-2-1-3-5-8/h1-5H,6-7H2,(H,10,12)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description In vitro 5-lipoxygenase inhibitory activity against calcium ionophore (A23187) induced LTB4 formation in human polymorphonuclear leukocytes.				J Med Chem 39: 3938-50 (1996) Article DOI: 10.1021/jm960372b BindingDB Entry DOI: 10.7270/Q2GQ6WWW
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus)	BDBM50053514 (5-Butyl-1-phenyl-[1,2,4]triazinan-3-one | 5-butyl-...) Show SMILES CCCCC1CN(NC(=O)N1)c1ccccc1 Show InChI InChI=1S/C13H19N3O/c1-2-3-7-11-10-16(15-13(17)14-11)12-8-5-4-6-9-12/h4-6,8-9,11H,2-3,7,10H2,1H3,(H2,14,15,17)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of 5-lipoxygenase catalysis in rat basophilic leukemia (RBL) cells by measuring 5-HETE product formation				J Med Chem 39: 3938-50 (1996) Article DOI: 10.1021/jm960372b BindingDB Entry DOI: 10.7270/Q2GQ6WWW
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Homo sapiens (Human))	BDBM50053480 (1-(6-Chloro-pyridin-2-yl)-5-methyl-[1,2,4]triazina...) Show SMILES CC1CN(NC(=O)N1)c1cccc(Cl)n1 Show InChI InChI=1S/C9H11ClN4O/c1-6-5-14(13-9(15)11-6)8-4-2-3-7(10)12-8/h2-4,6H,5H2,1H3,(H2,11,13,15)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description In vitro 5-lipoxygenase inhibitory activity against calcium ionophore (A23187) induced LTB4 formation in human polymorphonuclear leukocytes.				J Med Chem 39: 3938-50 (1996) Article DOI: 10.1021/jm960372b BindingDB Entry DOI: 10.7270/Q2GQ6WWW
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Homo sapiens (Human))	BDBM50053475 (5-Methyl-1-(6-methyl-pyridin-2-yl)-[1,2,4]triazina...) Show SMILES CC1CN(NC(=O)N1)c1cccc(C)n1 Show InChI InChI=1S/C10H14N4O/c1-7-4-3-5-9(11-7)14-6-8(2)12-10(15)13-14/h3-5,8H,6H2,1-2H3,(H2,12,13,15)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description In vitro 5-lipoxygenase inhibitory activity against calcium ionophore (A23187) induced LTB4 formation in human polymorphonuclear leukocytes.				J Med Chem 39: 3938-50 (1996) Article DOI: 10.1021/jm960372b BindingDB Entry DOI: 10.7270/Q2GQ6WWW
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Homo sapiens (Human))	BDBM50053478 (1-(3-Fluoro-phenyl)-5-methyl-[1,2,4]triazinan-3-on...) Show SMILES CC1CN(NC(=O)N1)c1cccc(F)c1 Show InChI InChI=1S/C10H12FN3O/c1-7-6-14(13-10(15)12-7)9-4-2-3-8(11)5-9/h2-5,7H,6H2,1H3,(H2,12,13,15)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description In vitro 5-lipoxygenase inhibitory activity against calcium ionophore (A23187) induced LTB4 formation in human polymorphonuclear leukocytes.				J Med Chem 39: 3938-50 (1996) Article DOI: 10.1021/jm960372b BindingDB Entry DOI: 10.7270/Q2GQ6WWW
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Homo sapiens (Human))	BDBM50280176 (1-(3-Bromo-phenyl)-tetrahydro-pyridazin-3-one | CH...) Show SMILES Brc1cccc(c1)N1CCCC(=O)N1 Show InChI InChI=1S/C10H11BrN2O/c11-8-3-1-4-9(7-8)13-6-2-5-10(14)12-13/h1,3-4,7H,2,5-6H2,(H,12,14)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article	n/a	n/a	1.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibitory activity against 5-lipoxygenase.				Bioorg Med Chem Lett 2: 1357-1360 (1992) Article DOI: 10.1016/S0960-894X(00)80512-0 BindingDB Entry DOI: 10.7270/Q2CC10M8
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus)	BDBM50009004 ((phenidone)1-Phenyl-pyrazolidin-3-one | 1-Phenyl-p...) Show SMILES O=C1CCN(N1)c1ccccc1 Show InChI InChI=1S/C9H10N2O/c12-9-6-7-11(10-9)8-4-2-1-3-5-8/h1-5H,6-7H2,(H,10,12)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of 5-lipoxygenase catalysis in rat basophilic leukemia (RBL) cells by measuring 5-HETE product formation				J Med Chem 39: 3938-50 (1996) Article DOI: 10.1021/jm960372b BindingDB Entry DOI: 10.7270/Q2GQ6WWW
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Homo sapiens (Human))	BDBM50009004 ((phenidone)1-Phenyl-pyrazolidin-3-one | 1-Phenyl-p...) Show SMILES O=C1CCN(N1)c1ccccc1 Show InChI InChI=1S/C9H10N2O/c12-9-6-7-11(10-9)8-4-2-1-3-5-8/h1-5H,6-7H2,(H,10,12)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article	n/a	n/a	1.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibitory activity against 5-lipoxygenase.				Bioorg Med Chem Lett 2: 1357-1360 (1992) Article DOI: 10.1016/S0960-894X(00)80512-0 BindingDB Entry DOI: 10.7270/Q2CC10M8
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Homo sapiens (Human))	BDBM50053495 (1-m-Tolyl-[1,2,4]triazinan-3-one | 1-m-tolyl-1,2,4...) Show SMILES Cc1cccc(c1)N1CCNC(=O)N1 Show InChI InChI=1S/C10H13N3O/c1-8-3-2-4-9(7-8)13-6-5-11-10(14)12-13/h2-4,7H,5-6H2,1H3,(H2,11,12,14)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description In vitro 5-lipoxygenase inhibitory activity against calcium ionophore (A23187) induced LTB4 formation in human polymorphonuclear leukocytes.				J Med Chem 39: 3938-50 (1996) Article DOI: 10.1021/jm960372b BindingDB Entry DOI: 10.7270/Q2GQ6WWW
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Homo sapiens (Human))	BDBM50053491 (1-(3-Chloro-phenyl)-[1,2,4]triazinan-3-one | CHEMB...) Show SMILES Clc1cccc(c1)N1CCNC(=O)N1 Show InChI InChI=1S/C9H10ClN3O/c10-7-2-1-3-8(6-7)13-5-4-11-9(14)12-13/h1-3,6H,4-5H2,(H2,11,12,14)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description In vitro 5-lipoxygenase inhibitory activity against calcium ionophore (A23187) induced LTB4 formation in human polymorphonuclear leukocytes.				J Med Chem 39: 3938-50 (1996) Article DOI: 10.1021/jm960372b BindingDB Entry DOI: 10.7270/Q2GQ6WWW
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus)	BDBM50053462 (1-(3-Thiophen-2-yl-phenyl)-[1,2,4]triazinan-3-one ...) Show SMILES O=C1NCCN(N1)c1cccc(c1)-c1cccs1 Show InChI InChI=1S/C13H13N3OS/c17-13-14-6-7-16(15-13)11-4-1-3-10(9-11)12-5-2-8-18-12/h1-5,8-9H,6-7H2,(H2,14,15,17)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of 5-lipoxygenase catalysis in rat basophilic leukemia (RBL) cells by measuring 5-HETE product formation				J Med Chem 39: 3938-50 (1996) Article DOI: 10.1021/jm960372b BindingDB Entry DOI: 10.7270/Q2GQ6WWW
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Homo sapiens (Human))	BDBM50053474 (1-(3-(methylthio)phenyl)-1,2,4-triazinan-3-one | 1...) Show SMILES CSc1cccc(c1)N1CCNC(=O)N1 Show InChI InChI=1S/C10H13N3OS/c1-15-9-4-2-3-8(7-9)13-6-5-11-10(14)12-13/h2-4,7H,5-6H2,1H3,(H2,11,12,14)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description In vitro 5-lipoxygenase inhibitory activity against calcium ionophore (A23187) induced LTB4 formation in human polymorphonuclear leukocytes.				J Med Chem 39: 3938-50 (1996) Article DOI: 10.1021/jm960372b BindingDB Entry DOI: 10.7270/Q2GQ6WWW
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus)	BDBM50053461 (1-(6-Bromo-pyridin-2-yl)-5-methyl-[1,2,4]triazinan...) Show SMILES CC1CN(NC(=O)N1)c1cccc(Br)n1 Show InChI InChI=1S/C9H11BrN4O/c1-6-5-14(13-9(15)11-6)8-4-2-3-7(10)12-8/h2-4,6H,5H2,1H3,(H2,11,13,15)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of 5-lipoxygenase catalysis in rat basophilic leukemia (RBL) cells by measuring 5-HETE product formation				J Med Chem 39: 3938-50 (1996) Article DOI: 10.1021/jm960372b BindingDB Entry DOI: 10.7270/Q2GQ6WWW
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Homo sapiens (Human))	BDBM50280196 (1-(3-Chloro-phenyl)-tetrahydro-pyridazin-3-one | C...) Show SMILES Clc1cccc(c1)N1CCCC(=O)N1 Show InChI InChI=1S/C10H11ClN2O/c11-8-3-1-4-9(7-8)13-6-2-5-10(14)12-13/h1,3-4,7H,2,5-6H2,(H,12,14)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article	n/a	n/a	2.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibitory activity against 5-lipoxygenase.				Bioorg Med Chem Lett 2: 1357-1360 (1992) Article DOI: 10.1016/S0960-894X(00)80512-0 BindingDB Entry DOI: 10.7270/Q2CC10M8
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus)	BDBM50053489 (1-(3-Bromo-phenyl)-5-methyl-[1,2,4]triazinan-3-one...) Show SMILES CC1CN(NC(=O)N1)c1cccc(Br)c1 Show InChI InChI=1S/C10H12BrN3O/c1-7-6-14(13-10(15)12-7)9-4-2-3-8(11)5-9/h2-5,7H,6H2,1H3,(H2,12,13,15)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of 5-lipoxygenase catalysis in rat basophilic leukemia (RBL) cells by measuring 5-HETE product formation				J Med Chem 39: 3938-50 (1996) Article DOI: 10.1021/jm960372b BindingDB Entry DOI: 10.7270/Q2GQ6WWW
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Homo sapiens (Human))	BDBM50053504 (5-Phenoxy-1-phenyl-[1,2,4]triazinan-3-one | CHEMBL...) Show SMILES O=C1NC(CN(N1)c1ccccc1)Oc1ccccc1 Show InChI InChI=1S/C15H15N3O2/c19-15-16-14(20-13-9-5-2-6-10-13)11-18(17-15)12-7-3-1-4-8-12/h1-10,14H,11H2,(H2,16,17,19)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description In vitro 5-lipoxygenase inhibitory activity against calcium ionophore (A23187) induced LTB4 formation in human polymorphonuclear leukocytes.				J Med Chem 39: 3938-50 (1996) Article DOI: 10.1021/jm960372b BindingDB Entry DOI: 10.7270/Q2GQ6WWW
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Homo sapiens (Human))	BDBM50053473 (5-(4-Fluoro-phenoxy)-1-phenyl-[1,2,4]triazinan-3-o...) Show SMILES Fc1ccc(OC2CN(NC(=O)N2)c2ccccc2)cc1 Show InChI InChI=1S/C15H14FN3O2/c16-11-6-8-13(9-7-11)21-14-10-19(18-15(20)17-14)12-4-2-1-3-5-12/h1-9,14H,10H2,(H2,17,18,20)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description In vitro 5-lipoxygenase inhibitory activity against calcium ionophore (A23187) induced LTB4 formation in human polymorphonuclear leukocytes.				J Med Chem 39: 3938-50 (1996) Article DOI: 10.1021/jm960372b BindingDB Entry DOI: 10.7270/Q2GQ6WWW
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus)	BDBM50053477 (1-(3-Chloro-phenyl)-5-methyl-[1,2,4]triazinan-3-on...) Show SMILES CC1CN(NC(=O)N1)c1cccc(Cl)c1 Show InChI InChI=1S/C10H12ClN3O/c1-7-6-14(13-10(15)12-7)9-4-2-3-8(11)5-9/h2-5,7H,6H2,1H3,(H2,12,13,15)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of 5-lipoxygenase catalysis in rat basophilic leukemia (RBL) cells by measuring 5-HETE product formation				J Med Chem 39: 3938-50 (1996) Article DOI: 10.1021/jm960372b BindingDB Entry DOI: 10.7270/Q2GQ6WWW
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Homo sapiens (Human))	BDBM50053477 (1-(3-Chloro-phenyl)-5-methyl-[1,2,4]triazinan-3-on...) Show SMILES CC1CN(NC(=O)N1)c1cccc(Cl)c1 Show InChI InChI=1S/C10H12ClN3O/c1-7-6-14(13-10(15)12-7)9-4-2-3-8(11)5-9/h2-5,7H,6H2,1H3,(H2,12,13,15)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description In vitro 5-lipoxygenase inhibitory activity against calcium ionophore (A23187) induced LTB4 formation in human polymorphonuclear leukocytes.				J Med Chem 39: 3938-50 (1996) Article DOI: 10.1021/jm960372b BindingDB Entry DOI: 10.7270/Q2GQ6WWW
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus)	BDBM50053503 (5-Methyl-1-(3-thiophen-2-yl-phenyl)-[1,2,4]triazin...) Show SMILES CC1CN(NC(=O)N1)c1cccc(c1)-c1cccs1 Show InChI InChI=1S/C14H15N3OS/c1-10-9-17(16-14(18)15-10)12-5-2-4-11(8-12)13-6-3-7-19-13/h2-8,10H,9H2,1H3,(H2,15,16,18)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of 5-lipoxygenase catalysis in rat basophilic leukemia (RBL) cells by measuring 5-HETE product formation				J Med Chem 39: 3938-50 (1996) Article DOI: 10.1021/jm960372b BindingDB Entry DOI: 10.7270/Q2GQ6WWW
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Homo sapiens (Human))	BDBM50053481 (1-(6-Fluoro-pyridin-2-yl)-[1,2,4]triazinan-3-one |...) Show SMILES Fc1cccc(n1)N1CCNC(=O)N1 Show InChI InChI=1S/C8H9FN4O/c9-6-2-1-3-7(11-6)13-5-4-10-8(14)12-13/h1-3H,4-5H2,(H2,10,12,14)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description In vitro 5-lipoxygenase inhibitory activity against calcium ionophore (A23187) induced LTB4 formation in human polymorphonuclear leukocytes.				J Med Chem 39: 3938-50 (1996) Article DOI: 10.1021/jm960372b BindingDB Entry DOI: 10.7270/Q2GQ6WWW
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Homo sapiens (Human))	BDBM50280180 (1-(3-Ethyl-phenyl)-tetrahydro-pyridazin-3-one | CH...) Show SMILES CCc1cccc(c1)N1CCCC(=O)N1 Show InChI InChI=1S/C12H16N2O/c1-2-10-5-3-6-11(9-10)14-8-4-7-12(15)13-14/h3,5-6,9H,2,4,7-8H2,1H3,(H,13,15)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article	n/a	n/a	3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibitory activity against 5-lipoxygenase.				Bioorg Med Chem Lett 2: 1357-1360 (1992) Article DOI: 10.1016/S0960-894X(00)80512-0 BindingDB Entry DOI: 10.7270/Q2CC10M8
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Homo sapiens (Human))	BDBM50053461 (1-(6-Bromo-pyridin-2-yl)-5-methyl-[1,2,4]triazinan...) Show SMILES CC1CN(NC(=O)N1)c1cccc(Br)n1 Show InChI InChI=1S/C9H11BrN4O/c1-6-5-14(13-9(15)11-6)8-4-2-3-7(10)12-8/h2-4,6H,5H2,1H3,(H2,11,13,15)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description In vitro 5-lipoxygenase inhibitory activity against calcium ionophore (A23187) induced LTB4 formation in human polymorphonuclear leukocytes.				J Med Chem 39: 3938-50 (1996) Article DOI: 10.1021/jm960372b BindingDB Entry DOI: 10.7270/Q2GQ6WWW
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Homo sapiens (Human))	BDBM50280175 (1-m-Tolyl-tetrahydro-pyridazin-3-one | CHEMBL30151) Show SMILES Cc1cccc(c1)N1CCCC(=O)N1 Show InChI InChI=1S/C11H14N2O/c1-9-4-2-5-10(8-9)13-7-3-6-11(14)12-13/h2,4-5,8H,3,6-7H2,1H3,(H,12,14)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article	n/a	n/a	3.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibitory activity against 5-lipoxygenase.				Bioorg Med Chem Lett 2: 1357-1360 (1992) Article DOI: 10.1016/S0960-894X(00)80512-0 BindingDB Entry DOI: 10.7270/Q2CC10M8
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus)	BDBM50053480 (1-(6-Chloro-pyridin-2-yl)-5-methyl-[1,2,4]triazina...) Show SMILES CC1CN(NC(=O)N1)c1cccc(Cl)n1 Show InChI InChI=1S/C9H11ClN4O/c1-6-5-14(13-9(15)11-6)8-4-2-3-7(10)12-8/h2-4,6H,5H2,1H3,(H2,11,13,15)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of 5-lipoxygenase catalysis in rat basophilic leukemia (RBL) cells by measuring 5-HETE product formation				J Med Chem 39: 3938-50 (1996) Article DOI: 10.1021/jm960372b BindingDB Entry DOI: 10.7270/Q2GQ6WWW
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus)	BDBM50053457 (1-(6-Bromo-pyridin-2-yl)-[1,2,4]triazinan-3-one | ...) Show SMILES Brc1cccc(n1)N1CCNC(=O)N1 Show InChI InChI=1S/C8H9BrN4O/c9-6-2-1-3-7(11-6)13-5-4-10-8(14)12-13/h1-3H,4-5H2,(H2,10,12,14)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of 5-lipoxygenase catalysis in rat basophilic leukemia (RBL) cells by measuring 5-HETE product formation				J Med Chem 39: 3938-50 (1996) Article DOI: 10.1021/jm960372b BindingDB Entry DOI: 10.7270/Q2GQ6WWW
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Homo sapiens (Human))	BDBM50053479 (1-(6-Methoxy-pyridin-2-yl)-[1,2,4]triazinan-3-one ...) Show SMILES COc1cccc(n1)N1CCNC(=O)N1 Show InChI InChI=1S/C9H12N4O2/c1-15-8-4-2-3-7(11-8)13-6-5-10-9(14)12-13/h2-4H,5-6H2,1H3,(H2,10,12,14)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description In vitro 5-lipoxygenase inhibitory activity against calcium ionophore (A23187) induced LTB4 formation in human polymorphonuclear leukocytes.				J Med Chem 39: 3938-50 (1996) Article DOI: 10.1021/jm960372b BindingDB Entry DOI: 10.7270/Q2GQ6WWW
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Homo sapiens (Human))	BDBM50280198 (1-p-Tolyl-pyrazolidin-3-one | CHEMBL29508) Show SMILES Cc1ccc(cc1)N1CCC(=O)N1 Show InChI InChI=1S/C10H12N2O/c1-8-2-4-9(5-3-8)12-7-6-10(13)11-12/h2-5H,6-7H2,1H3,(H,11,13)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article	n/a	n/a	3.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibitory activity against 5-lipoxygenase.				Bioorg Med Chem Lett 2: 1357-1360 (1992) Article DOI: 10.1016/S0960-894X(00)80512-0 BindingDB Entry DOI: 10.7270/Q2CC10M8
					More data for this Ligand-Target Pair

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