BindingDB PrimarySearch

Found 1801 hits with Last Name = 'lal' and Initial = 'a'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Urokinase plasminogen activator surface receptor (Homo sapiens (Human))	BDBM50005397 (CHEMBL2206684) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Research Center Curated by ChEMBL					Assay Description Binding affinity to uPAR				Bioorg Med Chem 20: 6989-7001 (2012) Article DOI: 10.1016/j.bmc.2012.10.010 BindingDB Entry DOI: 10.7270/Q26W9C80
National Research Center Curated by ChEMBL					More data for this Ligand-Target Pair
Urokinase plasminogen activator surface receptor (Homo sapiens (Human))	BDBM50402366 (CHEMBL2206696) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.00100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Research Center Curated by ChEMBL					Assay Description Binding affinity to uPAR				Bioorg Med Chem 20: 6989-7001 (2012) Article DOI: 10.1016/j.bmc.2012.10.010 BindingDB Entry DOI: 10.7270/Q26W9C80
National Research Center Curated by ChEMBL					More data for this Ligand-Target Pair
Urokinase plasminogen activator surface receptor (Homo sapiens (Human))	BDBM50005398 (CHEMBL2206694) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.00100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Research Center Curated by ChEMBL					Assay Description Binding affinity to uPAR				Bioorg Med Chem 20: 6989-7001 (2012) Article DOI: 10.1016/j.bmc.2012.10.010 BindingDB Entry DOI: 10.7270/Q26W9C80
National Research Center Curated by ChEMBL					More data for this Ligand-Target Pair
Urokinase plasminogen activator surface receptor (Homo sapiens (Human))	BDBM50402361 (CHEMBL2206680) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.00200	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Research Center Curated by ChEMBL					Assay Description Binding affinity to uPAR				Bioorg Med Chem 20: 6989-7001 (2012) Article DOI: 10.1016/j.bmc.2012.10.010 BindingDB Entry DOI: 10.7270/Q26W9C80
National Research Center Curated by ChEMBL					More data for this Ligand-Target Pair
Urokinase plasminogen activator surface receptor (Homo sapiens (Human))	BDBM50402378 (CHEMBL2206685) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.00200	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Research Center Curated by ChEMBL					Assay Description Binding affinity to uPAR				Bioorg Med Chem 20: 6989-7001 (2012) Article DOI: 10.1016/j.bmc.2012.10.010 BindingDB Entry DOI: 10.7270/Q26W9C80
National Research Center Curated by ChEMBL					More data for this Ligand-Target Pair
Urokinase plasminogen activator surface receptor (Homo sapiens (Human))	BDBM50402373 (CHEMBL2206691) Show SMILES Nc1c(cc(-c2ccccc2)n1-c1cccc(Cl)c1)C#N Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.00200	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Research Center Curated by ChEMBL					Assay Description Binding affinity to uPAR				Bioorg Med Chem 20: 6989-7001 (2012) Article DOI: 10.1016/j.bmc.2012.10.010 BindingDB Entry DOI: 10.7270/Q26W9C80
National Research Center Curated by ChEMBL					More data for this Ligand-Target Pair
Urokinase plasminogen activator surface receptor (Homo sapiens (Human))	BDBM50402360 (CHEMBL2206681) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	0.00200	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Research Center Curated by ChEMBL					Assay Description Binding affinity to uPAR				Bioorg Med Chem 20: 6989-7001 (2012) Article DOI: 10.1016/j.bmc.2012.10.010 BindingDB Entry DOI: 10.7270/Q26W9C80
National Research Center Curated by ChEMBL					More data for this Ligand-Target Pair
Urokinase plasminogen activator surface receptor (Homo sapiens (Human))	BDBM50402372 (CHEMBL2206692) Show SMILES Nc1c(cc(-c2ccccc2)n1-c1ccc(Cl)cc1)C#N Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.00300	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Research Center Curated by ChEMBL					Assay Description Binding affinity to uPAR				Bioorg Med Chem 20: 6989-7001 (2012) Article DOI: 10.1016/j.bmc.2012.10.010 BindingDB Entry DOI: 10.7270/Q26W9C80
National Research Center Curated by ChEMBL					More data for this Ligand-Target Pair
Urokinase plasminogen activator surface receptor (Homo sapiens (Human))	BDBM50402374 (CHEMBL2206690) Show SMILES Nc1c(cc(-c2ccccc2)n1-c1ccc(Br)cc1)C#N Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.00300	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Research Center Curated by ChEMBL					Assay Description Binding affinity to uPAR				Bioorg Med Chem 20: 6989-7001 (2012) Article DOI: 10.1016/j.bmc.2012.10.010 BindingDB Entry DOI: 10.7270/Q26W9C80
National Research Center Curated by ChEMBL					More data for this Ligand-Target Pair
Urokinase plasminogen activator surface receptor (Homo sapiens (Human))	BDBM50402371 (CHEMBL2206693) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	0.00300	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Research Center Curated by ChEMBL					Assay Description Binding affinity to uPAR				Bioorg Med Chem 20: 6989-7001 (2012) Article DOI: 10.1016/j.bmc.2012.10.010 BindingDB Entry DOI: 10.7270/Q26W9C80
National Research Center Curated by ChEMBL					More data for this Ligand-Target Pair
Urokinase plasminogen activator surface receptor (Homo sapiens (Human))	BDBM50402362 (CHEMBL2206700) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.00400	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Research Center Curated by ChEMBL					Assay Description Binding affinity to uPAR				Bioorg Med Chem 20: 6989-7001 (2012) Article DOI: 10.1016/j.bmc.2012.10.010 BindingDB Entry DOI: 10.7270/Q26W9C80
National Research Center Curated by ChEMBL					More data for this Ligand-Target Pair
Urokinase plasminogen activator surface receptor (Homo sapiens (Human))	BDBM50402363 (CHEMBL2206699) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.00400	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Research Center Curated by ChEMBL					Assay Description Binding affinity to uPAR				Bioorg Med Chem 20: 6989-7001 (2012) Article DOI: 10.1016/j.bmc.2012.10.010 BindingDB Entry DOI: 10.7270/Q26W9C80
National Research Center Curated by ChEMBL					More data for this Ligand-Target Pair
Urokinase plasminogen activator surface receptor (Homo sapiens (Human))	BDBM50402375 (CHEMBL2206689) Show SMILES Nc1c(cc(-c2ccccc2)n1-c1cccc(Br)c1)C#N Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.00400	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Research Center Curated by ChEMBL					Assay Description Binding affinity to uPAR				Bioorg Med Chem 20: 6989-7001 (2012) Article DOI: 10.1016/j.bmc.2012.10.010 BindingDB Entry DOI: 10.7270/Q26W9C80
National Research Center Curated by ChEMBL					More data for this Ligand-Target Pair
Urokinase plasminogen activator surface receptor (Homo sapiens (Human))	BDBM50402370 (CHEMBL2206683) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.00600	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Research Center Curated by ChEMBL					Assay Description Binding affinity to uPAR				Bioorg Med Chem 20: 6989-7001 (2012) Article DOI: 10.1016/j.bmc.2012.10.010 BindingDB Entry DOI: 10.7270/Q26W9C80
National Research Center Curated by ChEMBL					More data for this Ligand-Target Pair
Urokinase plasminogen activator surface receptor (Homo sapiens (Human))	BDBM50402367 (CHEMBL2206695) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.00700	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Research Center Curated by ChEMBL					Assay Description Binding affinity to uPAR				Bioorg Med Chem 20: 6989-7001 (2012) Article DOI: 10.1016/j.bmc.2012.10.010 BindingDB Entry DOI: 10.7270/Q26W9C80
National Research Center Curated by ChEMBL					More data for this Ligand-Target Pair
Urokinase plasminogen activator surface receptor (Homo sapiens (Human))	BDBM50402376 (CHEMBL2206688) Show SMILES Nc1c(cc(-c2ccccc2)n1-c1ccncc1)C#N Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.00800	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Research Center Curated by ChEMBL					Assay Description Binding affinity to uPAR				Bioorg Med Chem 20: 6989-7001 (2012) Article DOI: 10.1016/j.bmc.2012.10.010 BindingDB Entry DOI: 10.7270/Q26W9C80
National Research Center Curated by ChEMBL					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Homo sapiens (Human))	BDBM50130563 ((3R)-7-Hydroxy-N-[(1S)-1-{[(3R,4R)-4-(3-hydroxyphe...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	0.0100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Science and Technology Curated by ChEMBL					Assay Description Antagonist activity at kappa opioid receptor (unknown origin) assessed as stimulation of [35S]GTPgammaS				Eur J Med Chem 141: 632-647 (2017) Article DOI: 10.1016/j.ejmech.2017.10.012 BindingDB Entry DOI: 10.7270/Q2V98BQ2
University of Science and Technology Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Urokinase plasminogen activator surface receptor (Homo sapiens (Human))	BDBM50402364 (CHEMBL2206698) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.0110	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Research Center Curated by ChEMBL					Assay Description Binding affinity to uPAR				Bioorg Med Chem 20: 6989-7001 (2012) Article DOI: 10.1016/j.bmc.2012.10.010 BindingDB Entry DOI: 10.7270/Q26W9C80
National Research Center Curated by ChEMBL					More data for this Ligand-Target Pair
Urokinase plasminogen activator surface receptor (Homo sapiens (Human))	BDBM50402365 (CHEMBL2206697) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.0120	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Research Center Curated by ChEMBL					Assay Description Binding affinity to uPAR				Bioorg Med Chem 20: 6989-7001 (2012) Article DOI: 10.1016/j.bmc.2012.10.010 BindingDB Entry DOI: 10.7270/Q26W9C80
National Research Center Curated by ChEMBL					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Cavia porcellus (domestic guinea pig))	BDBM50130563 ((3R)-7-Hydroxy-N-[(1S)-1-{[(3R,4R)-4-(3-hydroxyphe...) Show SMILES Show InChI	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	0.0200	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Science and Technology Curated by ChEMBL					Assay Description Displacement of [3H]U69,593 from kappa opioid receptor in guinea pig brain membranes after 2 hrs				Eur J Med Chem 141: 632-647 (2017) Article DOI: 10.1016/j.ejmech.2017.10.012 BindingDB Entry DOI: 10.7270/Q2V98BQ2
University of Science and Technology Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Urokinase plasminogen activator surface receptor (Homo sapiens (Human))	BDBM50402377 (CHEMBL2206687) Show SMILES Nc1c(cc(-c2ccccc2)n1-c1ccccn1)C#N Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	0.0330	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Research Center Curated by ChEMBL					Assay Description Binding affinity to uPAR				Bioorg Med Chem 20: 6989-7001 (2012) Article DOI: 10.1016/j.bmc.2012.10.010 BindingDB Entry DOI: 10.7270/Q26W9C80
National Research Center Curated by ChEMBL					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Homo sapiens (Human))	BDBM50026603 (Buprenorphine \| CHEBI:3216) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	DrugBank PC cid PC sid UniChem Patents Similars	DrugBank Article PubMed	0.0400	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Science and Technology Curated by ChEMBL					Assay Description Antagonist activity at kappa opioid receptor (unknown origin) assessed as stimulation of [35S]GTPgammaS				Eur J Med Chem 141: 632-647 (2017) Article DOI: 10.1016/j.ejmech.2017.10.012 BindingDB Entry DOI: 10.7270/Q2V98BQ2
University of Science and Technology Curated by ChEMBL					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Cavia porcellus (domestic guinea pig))	BDBM50026614 (CHEMBL575508) Show SMILES Show InChI	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.0530	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Science and Technology Curated by ChEMBL					Assay Description Displacement of [3H]U69,593 from kappa opioid receptor in guinea pig brain membranes after 2 hrs				Eur J Med Chem 141: 632-647 (2017) Article DOI: 10.1016/j.ejmech.2017.10.012 BindingDB Entry DOI: 10.7270/Q2V98BQ2
University of Science and Technology Curated by ChEMBL					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Homo sapiens (Human))	BDBM50464462 (CHEMBL4283681) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	0.170	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Science and Technology Curated by ChEMBL					Assay Description Antagonist activity at human kappa opioid receptor expressed in CHO cells assessed as stimulation of [35S]GTPgammaS				Eur J Med Chem 141: 632-647 (2017) Article DOI: 10.1016/j.ejmech.2017.10.012 BindingDB Entry DOI: 10.7270/Q2V98BQ2
University of Science and Technology Curated by ChEMBL					More data for this Ligand-Target Pair
Cannabinoid receptor 2 (Homo sapiens (Human))	BDBM50072775 (2-((1R,2R,5R)-5-hydroxy-2-(3-hydroxypropyl)cyclohe...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	0.200	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The University of Mississippi Curated by ChEMBL					Assay Description Agonist activity at recombinant human full length CB2 receptor expressed in HEK293 cell membranes after 2 hrs by [35S]GTP-gammaS binding assay				Eur J Med Chem 143: 983-996 (2018) Article DOI: 10.1016/j.ejmech.2017.11.043 BindingDB Entry DOI: 10.7270/Q2D50QN8
The University of Mississippi Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Urokinase plasminogen activator surface receptor (Homo sapiens (Human))	BDBM50402379 (CHEMBL2206686) Show SMILES O=C(CC(C#N)C#N)c1ccccc1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem	Article PubMed	0.296	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Research Center Curated by ChEMBL					Assay Description Binding affinity to uPAR				Bioorg Med Chem 20: 6989-7001 (2012) Article DOI: 10.1016/j.bmc.2012.10.010 BindingDB Entry DOI: 10.7270/Q26W9C80
National Research Center Curated by ChEMBL					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1 (Homo sapiens (Human))	BDBM50412340 (CHEMBL540359) Show SMILES Show InChI	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.316	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Displacement of [3H]N-methyl Scopolamine from human muscarinic acetylcholine M1 receptor expressed in CHO cells by scintillation proximity assay				J Med Chem 51: 4866-9 (2008) Article DOI: 10.1021/jm800634k BindingDB Entry DOI: 10.7270/Q2MG7QQS
GlaxoSmithKline Curated by ChEMBL					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Homo sapiens (Human))	BDBM50072775 (2-((1R,2R,5R)-5-hydroxy-2-(3-hydroxypropyl)cyclohe...) Show SMILES Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	0.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The University of Mississippi Curated by ChEMBL					Assay Description Displacement of [3H]CP-55,940 from recombinant human full length CB1 receptor expressed in HEK293 cell membranes after 90 mins by topcount method				Eur J Med Chem 143: 983-996 (2018) Article DOI: 10.1016/j.ejmech.2017.11.043 BindingDB Entry DOI: 10.7270/Q2D50QN8
The University of Mississippi Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Cannabinoid receptor 2 (Homo sapiens (Human))	BDBM50072775 (2-((1R,2R,5R)-5-hydroxy-2-(3-hydroxypropyl)cyclohe...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	0.690	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The University of Mississippi Curated by ChEMBL					Assay Description Displacement of [3H]CP-55,940 from recombinant human full length CB2 receptor expressed in HEK293 cell membranes after 90 mins by topcount method				Eur J Med Chem 143: 983-996 (2018) Article DOI: 10.1016/j.ejmech.2017.11.043 BindingDB Entry DOI: 10.7270/Q2D50QN8
The University of Mississippi Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Cannabinoid receptor 1 (Homo sapiens (Human))	BDBM50072775 (2-((1R,2R,5R)-5-hydroxy-2-(3-hydroxypropyl)cyclohe...) Show SMILES Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	0.700	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The University of Mississippi Curated by ChEMBL					Assay Description Agonist activity at recombinant human full length CB1 receptor expressed in HEK293 cell membranes after 2 hrs by [35S]GTP-gammaS binding assay				Eur J Med Chem 143: 983-996 (2018) Article DOI: 10.1016/j.ejmech.2017.11.043 BindingDB Entry DOI: 10.7270/Q2D50QN8
The University of Mississippi Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Urokinase plasminogen activator surface receptor (Homo sapiens (Human))	BDBM50402368 (CHEMBL2206682) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	1.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Research Center Curated by ChEMBL					Assay Description Binding affinity to uPAR				Bioorg Med Chem 20: 6989-7001 (2012) Article DOI: 10.1016/j.bmc.2012.10.010 BindingDB Entry DOI: 10.7270/Q26W9C80
National Research Center Curated by ChEMBL					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Homo sapiens (Human))	BDBM50580098 (CHEMBL5075948) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	1.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human carbonic anhydrase 2 by stopped-flow CO2 hydration assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00756 BindingDB Entry DOI: 10.7270/Q2V4103G
TBA					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-4/beta-2 (Homo sapiens (Human))	BDBM82070 (CAS_29790-52-1 \| NICOTINE-L (BASE) \| Nicotine-D sa...) Show SMILES CN1CCC[C@H]1c1cccnc1 \|r\| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	Purchase KEGG PC cid PC sid PDB UniChem Similars	PDB Article PubMed	1.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Displacement of [125I] alpha bungarotoxin from human neuronal alpha4beta2 nAChR expressed in human SH-SY5Y cell membrane measured after 120 mins by T...				Citation and Details Article DOI: 10.1016/j.ejmech.2020.112403 BindingDB Entry DOI: 10.7270/Q2CF9TV2
TBA					More data for this Ligand-Target Pair				3D Structure (crystal)
Mu-type opioid receptor (Rattus norvegicus (rat))	BDBM50130563 ((3R)-7-Hydroxy-N-[(1S)-1-{[(3R,4R)-4-(3-hydroxyphe...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	2.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Science and Technology Curated by ChEMBL					Assay Description Displacement of [3H]DAMGO from mu-opioid receptor in rat brain membranes after 2 hrs				Eur J Med Chem 141: 632-647 (2017) Article DOI: 10.1016/j.ejmech.2017.10.012 BindingDB Entry DOI: 10.7270/Q2V98BQ2
University of Science and Technology Curated by ChEMBL					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Homo sapiens (Human))	BDBM50012152 (CHEMBL3264441) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Science and Technology Curated by ChEMBL					Assay Description Displacement of [3H]-diprenorphine from human kappa opioid receptor expressed in CHO cells after 1 hr				Eur J Med Chem 141: 632-647 (2017) Article DOI: 10.1016/j.ejmech.2017.10.012 BindingDB Entry DOI: 10.7270/Q2V98BQ2
University of Science and Technology Curated by ChEMBL					More data for this Ligand-Target Pair
Carbonic anhydrase 7 (Homo sapiens (Human))	BDBM10880 (AZA \| AZA2 \| AZM acetazolamide \| Acerazolamide, AA...) Show SMILES CC(=O)Nc1nnc(s1)S(N)(=O)=O Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank PDB Article PubMed	2.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human carbonic anhydrase 7 by stopped-flow CO2 hydration assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00756 BindingDB Entry DOI: 10.7270/Q2V4103G
TBA					More data for this Ligand-Target Pair				3D Structure (crystal)
Carbonic anhydrase 12 (Homo sapiens (Human))	BDBM50580101 (CHEMBL5081179) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	2.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human carbonic anhydrase 12 by stopped-flow CO2 hydration assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00756 BindingDB Entry DOI: 10.7270/Q2V4103G
TBA					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M2 (Homo sapiens (Human))	BDBM50412340 (CHEMBL540359) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.16	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Displacement of [3H]N-methyl Scopolamine from human muscarinic acetylcholine M2 receptor expressed in CHO cells coexpressed with Gqi5 by scintillatio...				J Med Chem 51: 4866-9 (2008) Article DOI: 10.1021/jm800634k BindingDB Entry DOI: 10.7270/Q2MG7QQS
GlaxoSmithKline Curated by ChEMBL					More data for this Ligand-Target Pair
Delta-type opioid receptor (Homo sapiens (Human))	BDBM50464462 (CHEMBL4283681) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	3.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Science and Technology Curated by ChEMBL					Assay Description Antagonist activity at human delta opioid receptor expressed in CHO cells assessed as stimulation of [35S]GTPgammaS				Eur J Med Chem 141: 632-647 (2017) Article DOI: 10.1016/j.ejmech.2017.10.012 BindingDB Entry DOI: 10.7270/Q2V98BQ2
University of Science and Technology Curated by ChEMBL					More data for this Ligand-Target Pair
Carbonic anhydrase 12 (Homo sapiens (Human))	BDBM50580100 (CHEMBL5089227) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	3.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human carbonic anhydrase 12 by stopped-flow CO2 hydration assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00756 BindingDB Entry DOI: 10.7270/Q2V4103G
TBA					More data for this Ligand-Target Pair
Carbonic anhydrase 9 (Homo sapiens (Human))	BDBM50580098 (CHEMBL5075948) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	3.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human carbonic anhydrase 9 by stopped-flow CO2 hydration assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00756 BindingDB Entry DOI: 10.7270/Q2V4103G
TBA					More data for this Ligand-Target Pair
Histone-lysine N-methyltransferase EHMT2 (Homo sapiens (Human))	BDBM50442103 (CHEMBL2441082) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	3.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of North Carolina at Chapel Hill Curated by ChEMBL					Assay Description Non-competitive inhibition of lysine methyltransferase G9a (unknown origin) using SAM as substrate by Michaelis-Menten kinetic assay				J Med Chem 56: 8931-42 (2013) Article DOI: 10.1021/jm401480r BindingDB Entry DOI: 10.7270/Q2NZ892T
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM50464462 (CHEMBL4283681) Show SMILES Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	5.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Science and Technology Curated by ChEMBL					Assay Description Antagonist activity at human mu opioid receptor expressed in CHO cells assessed as stimulation of [35S]GTPgammaS				Eur J Med Chem 141: 632-647 (2017) Article DOI: 10.1016/j.ejmech.2017.10.012 BindingDB Entry DOI: 10.7270/Q2V98BQ2
University of Science and Technology Curated by ChEMBL					More data for this Ligand-Target Pair
Carbonic anhydrase 12 (Homo sapiens (Human))	BDBM10880 (AZA \| AZA2 \| AZM acetazolamide \| Acerazolamide, AA...) Show SMILES CC(=O)Nc1nnc(s1)S(N)(=O)=O Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	5.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human CA12 by stopped-flow carbon dioxide hydration assay				Citation and Details Article DOI: 10.1016/j.ejmech.2020.112439 BindingDB Entry DOI: 10.7270/Q2057KNJ
TBA					More data for this Ligand-Target Pair				3D Structure (crystal)
Carbonic anhydrase 12 (Homo sapiens (Human))	BDBM10880 (AZA \| AZA2 \| AZM acetazolamide \| Acerazolamide, AA...) Show SMILES CC(=O)Nc1nnc(s1)S(N)(=O)=O Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	5.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human carbonic anhydrase 12 by stopped-flow CO2 hydration assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00756 BindingDB Entry DOI: 10.7270/Q2V4103G
TBA					More data for this Ligand-Target Pair				3D Structure (crystal)
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50474703 (CHEMBL1269) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	<6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Florida A and M University Curated by ChEMBL					Assay Description Displacement of [3H]7-OH-DPAT from human Dopamine receptor D3				J Med Chem 47: 497-508 (2004) Article DOI: 10.1021/jm0301033 BindingDB Entry DOI: 10.7270/Q2445Q6H
Florida A and M University Curated by ChEMBL					More data for this Ligand-Target Pair
D(4) dopamine receptor (Homo sapiens (Human))	BDBM50474703 (CHEMBL1269) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	<6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Florida A and M University Curated by ChEMBL					Assay Description Displacement of [3H]spiperone from human Dopamine receptor D4				J Med Chem 47: 497-508 (2004) Article DOI: 10.1021/jm0301033 BindingDB Entry DOI: 10.7270/Q2445Q6H
Florida A and M University Curated by ChEMBL					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50474703 (CHEMBL1269) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	<6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Florida A and M University Curated by ChEMBL					Assay Description Displacement of [3H]spiperone from human Dopamine receptor D2				J Med Chem 47: 497-508 (2004) Article DOI: 10.1021/jm0301033 BindingDB Entry DOI: 10.7270/Q2445Q6H
Florida A and M University Curated by ChEMBL					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Homo sapiens (Human))	BDBM50580099 (CHEMBL5078071) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	6.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human carbonic anhydrase 2 by stopped-flow CO2 hydration assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00756 BindingDB Entry DOI: 10.7270/Q2V4103G
TBA					More data for this Ligand-Target Pair
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50001884 (2-[4-(4-Methyl-benzyl)-piperazin-1-yl]-1-(2-methyl...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	6.62	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Florida A and M University Curated by ChEMBL					Assay Description Displacement of [3H]7-OH-DPAT from human Dopamine receptor D3				J Med Chem 47: 497-508 (2004) Article DOI: 10.1021/jm0301033 BindingDB Entry DOI: 10.7270/Q2445Q6H
Florida A and M University Curated by ChEMBL					More data for this Ligand-Target Pair

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