Compile Data Set for Download or QSAR

Found 290 hits with Last Name = 'albanese' and Initial = 'c'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cell division cycle 7-related protein kinase (Homo sapiens (Human))	BDBM50329419 (5-(2-amino-5-bromopyrimidin-4-yl)-2-p-tolyl-1H-pyr...) Show SMILES NC(=O)c1cc([nH]c1-c1ccccc1)-c1nc(N)ncc1Br Show InChI InChI=1S/C15H12BrN5O/c16-10-7-19-15(18)21-13(10)11-6-9(14(17)22)12(20-11)8-4-2-1-3-5-8/h1-7,20H,(H2,17,22)(H2,18,19,21)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Nerviano Medical Sciences Srl Curated by ChEMBL					Assay Description Inhibition of Cdc7				J Med Chem 53: 7296-315 (2010) Article DOI: 10.1021/jm100504d BindingDB Entry DOI: 10.7270/Q24T6JM3
					More data for this Ligand-Target Pair
Cyclin-A2/Cyclin-dependent kinase 2 (Homo sapiens (Human))	BDBM7107 ((2S)-N-(5-Cyclopropyl-1H-pyrazol-3-yl)-2-[4-(1-oxo...) Show SMILES C[C@H](C(=O)Nc1cc(n[nH]1)C1CC1)c1ccc(cc1)N1Cc2ccccc2C1=O |r| Show InChI InChI=1S/C23H22N4O2/c1-14(22(28)24-21-12-20(25-26-21)16-6-7-16)15-8-10-18(11-9-15)27-13-17-4-2-3-5-19(17)23(27)29/h2-5,8-12,14,16H,6-7,13H2,1H3,(H2,24,25,26,28)/t14-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Nerviano Medical Sciences					Assay Description The biochemical activity of compounds was determined by incubation with specific enzymes and substrates in the presence ATP/[gamma-33P] ATP. After in...				J Med Chem 48: 2944-56 (2005) Article DOI: 10.1021/jm0408870 BindingDB Entry DOI: 10.7270/Q2WQ020R
					More data for this Ligand-Target Pair
Cyclin-A2/Cyclin-dependent kinase 2 (Homo sapiens (Human))	BDBM7111 ((2S)-N-(5-Cyclopropyl-1H-pyrazol-3-yl)-2-[4-(2-oxo...) Show SMILES C[C@H](C(=O)Nc1cc(n[nH]1)C1CC1)c1ccc(cc1)N1CCNC1=O |r| Show InChI InChI=1S/C18H21N5O2/c1-11(17(24)20-16-10-15(21-22-16)13-2-3-13)12-4-6-14(7-5-12)23-9-8-19-18(23)25/h4-7,10-11,13H,2-3,8-9H2,1H3,(H,19,25)(H2,20,21,22,24)/t11-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Nerviano Medical Sciences					Assay Description The biochemical activity of compounds was determined by incubation with specific enzymes and substrates in the presence ATP/[gamma-33P] ATP. After in...				J Med Chem 48: 2944-56 (2005) Article DOI: 10.1021/jm0408870 BindingDB Entry DOI: 10.7270/Q2WQ020R
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 5 activator 1 (Homo sapiens (Human))	BDBM50378657 (CHEMBL1230607) Show SMILES CC(C)CC(=O)Nc1[nH]nc2c1CN(C(=O)C1CCN(C)CC1)C2(C)C Show InChI InChI=1S/C19H31N5O2/c1-12(2)10-15(25)20-17-14-11-24(19(3,4)16(14)21-22-17)18(26)13-6-8-23(5)9-7-13/h12-13H,6-11H2,1-5H3,(H2,20,21,22,25)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
Nerviano Medical Sciences Srl Curated by ChEMBL					Assay Description Inhibition of CDK5/p25 by scintillation proximity assay				Bioorg Med Chem 18: 1844-53 (2010) Article DOI: 10.1016/j.bmc.2010.01.042 BindingDB Entry DOI: 10.7270/Q21R6RG5
					More data for this Ligand-Target Pair
Cell division cycle 7-related protein kinase (Homo sapiens (Human))	BDBM50329420 (5-(2-amino-5-chloropyrimidin-4-yl)-2-p-tolyl-1H-py...) Show SMILES NC(=O)c1cc([nH]c1-c1ccccc1)-c1nc(N)ncc1Cl Show InChI InChI=1S/C15H12ClN5O/c16-10-7-19-15(18)21-13(10)11-6-9(14(17)22)12(20-11)8-4-2-1-3-5-8/h1-7,20H,(H2,17,22)(H2,18,19,21)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
Nerviano Medical Sciences Srl Curated by ChEMBL					Assay Description Inhibition of Cdc7				J Med Chem 53: 7296-315 (2010) Article DOI: 10.1021/jm100504d BindingDB Entry DOI: 10.7270/Q24T6JM3
					More data for this Ligand-Target Pair
Cyclin-A1/Cyclin-A2/Cyclin-dependent kinase 2 (Homo sapiens (Human))	BDBM50027427 (CHEMBL1744453) Show SMILES CN1CCC(CC1)C(=O)N1Cc2c(NC(=O)c3ccsc3)n[nH]c2C1(C)C Show InChI InChI=1S/C19H25N5O2S/c1-19(2)15-14(10-24(19)18(26)12-4-7-23(3)8-5-12)16(22-21-15)20-17(25)13-6-9-27-11-13/h6,9,11-12H,4-5,7-8,10H2,1-3H3,(H2,20,21,22,25)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
Nerviano Medical Sciences Srl Curated by ChEMBL					Assay Description Inhibition of human CDK2/cyclin A expressed in Escherichia coli BL21 by scintillation proximity assay				Bioorg Med Chem 18: 1844-53 (2010) Article DOI: 10.1016/j.bmc.2010.01.042 BindingDB Entry DOI: 10.7270/Q21R6RG5
					More data for this Ligand-Target Pair
Cell division cycle 7-related protein kinase (Homo sapiens (Human))	BDBM50329416 (2-(2-Fluoro-phenyl)-5-pyridin-4-yl-1H-pyrrole-3-ca...) Show SMILES NC(=O)c1cc([nH]c1-c1ccccc1F)-c1ccncc1 Show InChI InChI=1S/C16H12FN3O/c17-13-4-2-1-3-11(13)15-12(16(18)21)9-14(20-15)10-5-7-19-8-6-10/h1-9,20H,(H2,18,21)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
Nerviano Medical Sciences Srl Curated by ChEMBL					Assay Description Inhibition of Cdc7				J Med Chem 53: 7296-315 (2010) Article DOI: 10.1021/jm100504d BindingDB Entry DOI: 10.7270/Q24T6JM3
					More data for this Ligand-Target Pair
Cell division cycle 7-related protein kinase (Homo sapiens (Human))	BDBM50329417 (5-(3-Fluoro-pyridin-4-yl)-2-phenyl-1H-pyrrole-3-ca...) Show SMILES NC(=O)c1cc([nH]c1-c1ccccc1)-c1ccncc1F Show InChI InChI=1S/C16H12FN3O/c17-13-9-19-7-6-11(13)14-8-12(16(18)21)15(20-14)10-4-2-1-3-5-10/h1-9,20H,(H2,18,21)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
Nerviano Medical Sciences Srl Curated by ChEMBL					Assay Description Inhibition of Cdc7				J Med Chem 53: 7296-315 (2010) Article DOI: 10.1021/jm100504d BindingDB Entry DOI: 10.7270/Q24T6JM3
					More data for this Ligand-Target Pair
Cyclin-A1/Cyclin-A2/Cyclin-dependent kinase 2 (Homo sapiens (Human))	BDBM50378657 (CHEMBL1230607) Show SMILES CC(C)CC(=O)Nc1[nH]nc2c1CN(C(=O)C1CCN(C)CC1)C2(C)C Show InChI InChI=1S/C19H31N5O2/c1-12(2)10-15(25)20-17-14-11-24(19(3,4)16(14)21-22-17)18(26)13-6-8-23(5)9-7-13/h12-13H,6-11H2,1-5H3,(H2,20,21,22,25)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
Nerviano Medical Sciences Srl Curated by ChEMBL					Assay Description Inhibition of human CDK2/cyclin A expressed in Escherichia coli BL21 by scintillation proximity assay				Bioorg Med Chem 18: 1844-53 (2010) Article DOI: 10.1016/j.bmc.2010.01.042 BindingDB Entry DOI: 10.7270/Q21R6RG5
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 2/G1/S-specific cyclin-E1 (Homo sapiens (Human))	BDBM50378657 (CHEMBL1230607) Show SMILES CC(C)CC(=O)Nc1[nH]nc2c1CN(C(=O)C1CCN(C)CC1)C2(C)C Show InChI InChI=1S/C19H31N5O2/c1-12(2)10-15(25)20-17-14-11-24(19(3,4)16(14)21-22-17)18(26)13-6-8-23(5)9-7-13/h12-13H,6-11H2,1-5H3,(H2,20,21,22,25)	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
Nerviano Medical Sciences Srl Curated by ChEMBL					Assay Description Inhibition of CDK2/cyclin E by scintillation proximity assay				Bioorg Med Chem 18: 1844-53 (2010) Article DOI: 10.1016/j.bmc.2010.01.042 BindingDB Entry DOI: 10.7270/Q21R6RG5
					More data for this Ligand-Target Pair
Cell division cycle 7-related protein kinase (Homo sapiens (Human))	BDBM50329418 (2-Phenyl-5-pyridin-4-yl-1H-pyrrole-3-carboxamide |...) Show SMILES NC(=O)c1cc([nH]c1-c1ccccc1)-c1ccncc1 Show InChI InChI=1S/C16H13N3O/c17-16(20)13-10-14(11-6-8-18-9-7-11)19-15(13)12-4-2-1-3-5-12/h1-10,19H,(H2,17,20)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
Nerviano Medical Sciences Srl Curated by ChEMBL					Assay Description Inhibition of Cdc7				J Med Chem 53: 7296-315 (2010) Article DOI: 10.1021/jm100504d BindingDB Entry DOI: 10.7270/Q24T6JM3
					More data for this Ligand-Target Pair
Cyclin-A1/Cyclin-A2/Cyclin-dependent kinase 2 (Homo sapiens (Human))	BDBM50027423 (CHEMBL1744456) Show SMILES CN1CCC(CC1)C(=O)N1Cc2c(NC(=O)C3CCC3)n[nH]c2C1(C)C Show InChI InChI=1S/C19H29N5O2/c1-19(2)15-14(16(22-21-15)20-17(25)12-5-4-6-12)11-24(19)18(26)13-7-9-23(3)10-8-13/h12-13H,4-11H2,1-3H3,(H2,20,21,22,25)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
Nerviano Medical Sciences Srl Curated by ChEMBL					Assay Description Inhibition of human CDK2/cyclin A expressed in Escherichia coli BL21 by scintillation proximity assay				Bioorg Med Chem 18: 1844-53 (2010) Article DOI: 10.1016/j.bmc.2010.01.042 BindingDB Entry DOI: 10.7270/Q21R6RG5
					More data for this Ligand-Target Pair
Cell division cycle 7-related protein kinase (Homo sapiens (Human))	BDBM27344 (2-(pyridin-4-yl)-1H,4H,5H,6H,7H-pyrrolo[3,2-c]pyri...) Show SMILES O=C1NCCc2[nH]c(cc12)-c1ccncc1 Show InChI InChI=1S/C12H11N3O/c16-12-9-7-11(8-1-4-13-5-2-8)15-10(9)3-6-14-12/h1-2,4-5,7,15H,3,6H2,(H,14,16)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
Nerviano Medical Sciences Oncology Curated by ChEMBL					Assay Description Inhibition of cdc7				Nat Chem Biol 4: 357-65 (2008) Article DOI: 10.1038/nchembio.90 BindingDB Entry DOI: 10.7270/Q2DV1KVK
					More data for this Ligand-Target Pair				3D Structure (crystal)
Cell division cycle 7-related protein kinase (Homo sapiens (Human))	BDBM27344 (2-(pyridin-4-yl)-1H,4H,5H,6H,7H-pyrrolo[3,2-c]pyri...) Show SMILES O=C1NCCc2[nH]c(cc12)-c1ccncc1 Show InChI InChI=1S/C12H11N3O/c16-12-9-7-11(8-1-4-13-5-2-8)15-10(9)3-6-14-12/h1-2,4-5,7,15H,3,6H2,(H,14,16)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
Nerviano Medical Sciences Srl Curated by ChEMBL					Assay Description Inhibition of Cdc7				J Med Chem 53: 7296-315 (2010) Article DOI: 10.1021/jm100504d BindingDB Entry DOI: 10.7270/Q24T6JM3
					More data for this Ligand-Target Pair				3D Structure (crystal)
Cyclin-A1/Cyclin-A2/Cyclin-dependent kinase 2 (Homo sapiens (Human))	BDBM50027430 (CHEMBL1744452) Show SMILES CN1CCC(CC1)C(=O)N1Cc2c(NC(=O)c3cccs3)n[nH]c2C1(C)C Show InChI InChI=1S/C19H25N5O2S/c1-19(2)15-13(11-24(19)18(26)12-6-8-23(3)9-7-12)16(22-21-15)20-17(25)14-5-4-10-27-14/h4-5,10,12H,6-9,11H2,1-3H3,(H2,20,21,22,25)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
Nerviano Medical Sciences Srl Curated by ChEMBL					Assay Description Inhibition of human CDK2/cyclin A expressed in Escherichia coli BL21 by scintillation proximity assay				Bioorg Med Chem 18: 1844-53 (2010) Article DOI: 10.1016/j.bmc.2010.01.042 BindingDB Entry DOI: 10.7270/Q21R6RG5
					More data for this Ligand-Target Pair
Cyclin-A1/Cyclin-A2/Cyclin-dependent kinase 2 (Homo sapiens (Human))	BDBM50027392 (CHEMBL596978) Show SMILES CN1CCC(CC1)C(=O)N1Cc2c(NC(=O)Nc3cccc(F)c3)n[nH]c2C1(C)C Show InChI InChI=1S/C21H27FN6O2/c1-21(2)17-16(12-28(21)19(29)13-7-9-27(3)10-8-13)18(26-25-17)24-20(30)23-15-6-4-5-14(22)11-15/h4-6,11,13H,7-10,12H2,1-3H3,(H3,23,24,25,26,30)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
Nerviano Medical Sciences Srl Curated by ChEMBL					Assay Description Inhibition of human CDK2/cyclin A expressed in Escherichia coli BL21 by scintillation proximity assay				Bioorg Med Chem 18: 1844-53 (2010) Article DOI: 10.1016/j.bmc.2010.01.042 BindingDB Entry DOI: 10.7270/Q21R6RG5
					More data for this Ligand-Target Pair
Cyclin-H/Cyclin-dependent kinase 7 (Homo sapiens (Human))	BDBM50378657 (CHEMBL1230607) Show SMILES CC(C)CC(=O)Nc1[nH]nc2c1CN(C(=O)C1CCN(C)CC1)C2(C)C Show InChI InChI=1S/C19H31N5O2/c1-12(2)10-15(25)20-17-14-11-24(19(3,4)16(14)21-22-17)18(26)13-6-8-23(5)9-7-13/h12-13H,6-11H2,1-5H3,(H2,20,21,22,25)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
Nerviano Medical Sciences Srl Curated by ChEMBL					Assay Description Inhibition of CDK7/cyclin H by scintillation proximity assay				Bioorg Med Chem 18: 1844-53 (2010) Article DOI: 10.1016/j.bmc.2010.01.042 BindingDB Entry DOI: 10.7270/Q21R6RG5
					More data for this Ligand-Target Pair
Cyclin-A2/Cyclin-dependent kinase 2 (Homo sapiens (Human))	BDBM7114 (3-Aminopyrazole deriv. 27 | N-(5-Cyclopropyl-1H-py...) Show SMILES CC(C(=O)Nc1cc(n[nH]1)C1CC1)c1ccc(cc1)-n1cc[nH]c1=O Show InChI InChI=1S/C18H19N5O2/c1-11(17(24)20-16-10-15(21-22-16)13-2-3-13)12-4-6-14(7-5-12)23-9-8-19-18(23)25/h4-11,13H,2-3H2,1H3,(H,19,25)(H2,20,21,22,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
Nerviano Medical Sciences					Assay Description The biochemical activity of compounds was determined by incubation with specific enzymes and substrates in the presence ATP/[gamma-33P] ATP. After in...				J Med Chem 48: 2944-56 (2005) Article DOI: 10.1021/jm0408870 BindingDB Entry DOI: 10.7270/Q2WQ020R
					More data for this Ligand-Target Pair				3D Structure (crystal)
Cyclin-A1/Cyclin-A2/Cyclin-dependent kinase 2 (Homo sapiens (Human))	BDBM50027396 (CHEMBL603243) Show SMILES CCCNC(=O)Nc1n[nH]c2c1CN(C(=O)C1CCN(C)CC1)C2(C)C Show InChI InChI=1S/C18H30N6O2/c1-5-8-19-17(26)20-15-13-11-24(18(2,3)14(13)21-22-15)16(25)12-6-9-23(4)10-7-12/h12H,5-11H2,1-4H3,(H3,19,20,21,22,26)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
Nerviano Medical Sciences Srl Curated by ChEMBL					Assay Description Inhibition of human CDK2/cyclin A expressed in Escherichia coli BL21 by scintillation proximity assay				Bioorg Med Chem 18: 1844-53 (2010) Article DOI: 10.1016/j.bmc.2010.01.042 BindingDB Entry DOI: 10.7270/Q21R6RG5
					More data for this Ligand-Target Pair
Cyclin-A1/Cyclin-A2/Cyclin-dependent kinase 2 (Homo sapiens (Human))	BDBM50027421 (CHEMBL1744457) Show SMILES CCN1CCC(CC1)C(=O)N1Cc2c(NC(=O)CC(C)C)n[nH]c2C1(C)C Show InChI InChI=1S/C20H33N5O2/c1-6-24-9-7-14(8-10-24)19(27)25-12-15-17(20(25,4)5)22-23-18(15)21-16(26)11-13(2)3/h13-14H,6-12H2,1-5H3,(H2,21,22,23,26)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
Nerviano Medical Sciences Srl Curated by ChEMBL					Assay Description Inhibition of human CDK2/cyclin A expressed in Escherichia coli BL21 by scintillation proximity assay				Bioorg Med Chem 18: 1844-53 (2010) Article DOI: 10.1016/j.bmc.2010.01.042 BindingDB Entry DOI: 10.7270/Q21R6RG5
					More data for this Ligand-Target Pair
Cyclin-A1/Cyclin-A2/Cyclin-dependent kinase 2 (Homo sapiens (Human))	BDBM50027416 (CHEMBL599249) Show SMILES CN1CCC(CC1)C(=O)N1Cc2c(NC(=O)c3cccc(F)c3)n[nH]c2C1(C)C Show InChI InChI=1S/C21H26FN5O2/c1-21(2)17-16(12-27(21)20(29)13-7-9-26(3)10-8-13)18(25-24-17)23-19(28)14-5-4-6-15(22)11-14/h4-6,11,13H,7-10,12H2,1-3H3,(H2,23,24,25,28)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
Nerviano Medical Sciences Srl Curated by ChEMBL					Assay Description Inhibition of human CDK2/cyclin A expressed in Escherichia coli BL21 by scintillation proximity assay				Bioorg Med Chem 18: 1844-53 (2010) Article DOI: 10.1016/j.bmc.2010.01.042 BindingDB Entry DOI: 10.7270/Q21R6RG5
					More data for this Ligand-Target Pair
Cell division cycle 7-related protein kinase (Homo sapiens (Human))	BDBM50329415 (2-(4-Fluoro-phenyl)-5-pyridin-4-yl-1H-pyrrole-3-ca...) Show SMILES NC(=O)c1cc([nH]c1-c1ccc(F)cc1)-c1ccncc1 Show InChI InChI=1S/C16H12FN3O/c17-12-3-1-11(2-4-12)15-13(16(18)21)9-14(20-15)10-5-7-19-8-6-10/h1-9,20H,(H2,18,21)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
Nerviano Medical Sciences Srl Curated by ChEMBL					Assay Description Inhibition of Cdc7				J Med Chem 53: 7296-315 (2010) Article DOI: 10.1021/jm100504d BindingDB Entry DOI: 10.7270/Q24T6JM3
					More data for this Ligand-Target Pair
Cyclin-A1/Cyclin-A2/Cyclin-dependent kinase 2 (Homo sapiens (Human))	BDBM50027404 (CHEMBL603478) Show SMILES CN1CCC(CC1)C(=O)N1Cc2c(NC(=O)c3ccc(F)c(F)c3)n[nH]c2C1(C)C Show InChI InChI=1S/C21H25F2N5O2/c1-21(2)17-14(11-28(21)20(30)12-6-8-27(3)9-7-12)18(26-25-17)24-19(29)13-4-5-15(22)16(23)10-13/h4-5,10,12H,6-9,11H2,1-3H3,(H2,24,25,26,29)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
Nerviano Medical Sciences Srl Curated by ChEMBL					Assay Description Inhibition of human CDK2/cyclin A expressed in Escherichia coli BL21 by scintillation proximity assay				Bioorg Med Chem 18: 1844-53 (2010) Article DOI: 10.1016/j.bmc.2010.01.042 BindingDB Entry DOI: 10.7270/Q21R6RG5
					More data for this Ligand-Target Pair
Cyclin-A1/Cyclin-A2/Cyclin-dependent kinase 2 (Homo sapiens (Human))	BDBM50027413 (CHEMBL598221) Show SMILES CN1CCC(CC1)C(=O)N1Cc2c(NC(=O)c3ccc(Cl)cc3)n[nH]c2C1(C)C Show InChI InChI=1S/C21H26ClN5O2/c1-21(2)17-16(12-27(21)20(29)14-8-10-26(3)11-9-14)18(25-24-17)23-19(28)13-4-6-15(22)7-5-13/h4-7,14H,8-12H2,1-3H3,(H2,23,24,25,28)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
Nerviano Medical Sciences Srl Curated by ChEMBL					Assay Description Inhibition of human CDK2/cyclin A expressed in Escherichia coli BL21 by scintillation proximity assay				Bioorg Med Chem 18: 1844-53 (2010) Article DOI: 10.1016/j.bmc.2010.01.042 BindingDB Entry DOI: 10.7270/Q21R6RG5
					More data for this Ligand-Target Pair
Cyclin-A1/Cyclin-A2/Cyclin-dependent kinase 2 (Homo sapiens (Human))	BDBM50027424 (CHEMBL1744455) Show SMILES CN1CCC(CC1)C(=O)N1Cc2c(NC(=O)C3CC3)n[nH]c2C1(C)C Show InChI InChI=1S/C18H27N5O2/c1-18(2)14-13(15(21-20-14)19-16(24)11-4-5-11)10-23(18)17(25)12-6-8-22(3)9-7-12/h11-12H,4-10H2,1-3H3,(H2,19,20,21,24)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
Nerviano Medical Sciences Srl Curated by ChEMBL					Assay Description Inhibition of human CDK2/cyclin A expressed in Escherichia coli BL21 by scintillation proximity assay				Bioorg Med Chem 18: 1844-53 (2010) Article DOI: 10.1016/j.bmc.2010.01.042 BindingDB Entry DOI: 10.7270/Q21R6RG5
					More data for this Ligand-Target Pair
Cyclin-A1/Cyclin-A2/Cyclin-dependent kinase 2 (Homo sapiens (Human))	BDBM50027403 (CHEMBL603887) Show SMILES CN1CCC(CC1)C(=O)N1Cc2c(NC(=O)c3cc(F)cc(F)c3)n[nH]c2C1(C)C Show InChI InChI=1S/C21H25F2N5O2/c1-21(2)17-16(11-28(21)20(30)12-4-6-27(3)7-5-12)18(26-25-17)24-19(29)13-8-14(22)10-15(23)9-13/h8-10,12H,4-7,11H2,1-3H3,(H2,24,25,26,29)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	16	n/a	n/a	n/a	n/a	n/a	n/a
Nerviano Medical Sciences Srl Curated by ChEMBL					Assay Description Inhibition of human CDK2/cyclin A expressed in Escherichia coli BL21 by scintillation proximity assay				Bioorg Med Chem 18: 1844-53 (2010) Article DOI: 10.1016/j.bmc.2010.01.042 BindingDB Entry DOI: 10.7270/Q21R6RG5
					More data for this Ligand-Target Pair
Cyclin-A1/Cyclin-A2/Cyclin-dependent kinase 2 (Homo sapiens (Human))	BDBM50027411 (CHEMBL1744450) Show SMILES OC[C@H]1O[C@@](CO)(O[C@H]2O[C@H](CO[C@H]3O[C@H](CO)[C@H](O)[C@H](O)[C@H]3O)[C@@H](O)[C@H](O)[C@H]2O)[C@@H](O)[C@@H]1O.OC[C@H]1O[C@@](CO)(O[C@@H]2O[C@H](CO[C@H]3O[C@H](CO)[C@H](O)[C@H](O)[C@H]3O)[C@@H](O)[C@H](O)[C@H]2O)[C@@H](O)[C@@H]1O Show InChI InChI=1S/C18H32O16/c19-1-5-8(22)11(25)13(27)16(31-5)30-3-7-9(23)12(26)14(28)17(32-7)34-18(4-21)15(29)10(24)6(2-20)33-18/h5-17,19-29H,1-4H2/t5-,6-,7-,8+,9-,10-,11+,12+,13-,14-,15+,16+,17+,18+/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	16	n/a	n/a	n/a	n/a	n/a	n/a
Nerviano Medical Sciences Srl Curated by ChEMBL					Assay Description Inhibition of human CDK2/cyclin A expressed in Escherichia coli BL21 by scintillation proximity assay				Bioorg Med Chem 18: 1844-53 (2010) Article DOI: 10.1016/j.bmc.2010.01.042 BindingDB Entry DOI: 10.7270/Q21R6RG5
					More data for this Ligand-Target Pair
Cyclin-A2/Cyclin-dependent kinase 2 (Homo sapiens (Human))	BDBM7112 (3-Aminopyrazole deriv. 25 | N-(5-cyclopropyl-1H-py...) Show SMILES CC(C(=O)Nc1cc(n[nH]1)C1CC1)c1ccc(cc1)-n1cc(O)[nH]c1=O Show InChI InChI=1S/C18H19N5O3/c1-10(17(25)19-15-8-14(21-22-15)12-2-3-12)11-4-6-13(7-5-11)23-9-16(24)20-18(23)26/h4-10,12,24H,2-3H2,1H3,(H,20,26)(H2,19,21,22,25)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	17	n/a	n/a	n/a	n/a	n/a	n/a
Nerviano Medical Sciences					Assay Description The biochemical activity of compounds was determined by incubation with specific enzymes and substrates in the presence ATP/[gamma-33P] ATP. After in...				J Med Chem 48: 2944-56 (2005) Article DOI: 10.1021/jm0408870 BindingDB Entry DOI: 10.7270/Q2WQ020R
					More data for this Ligand-Target Pair
Cyclin-A2/Cyclin-dependent kinase 2 (Homo sapiens (Human))	BDBM7118 ((2S)-N-(5-Cyclopropyl-1H-pyrazol-3-yl)-2-[4-(3-met...) Show SMILES C[C@H](C(=O)Nc1cc(n[nH]1)C1CC1)c1ccc(cc1)N1CCN(C)C1=O |r| Show InChI InChI=1S/C19H23N5O2/c1-12(18(25)20-17-11-16(21-22-17)14-3-4-14)13-5-7-15(8-6-13)24-10-9-23(2)19(24)26/h5-8,11-12,14H,3-4,9-10H2,1-2H3,(H2,20,21,22,25)/t12-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	17	n/a	n/a	n/a	n/a	n/a	n/a
Nerviano Medical Sciences					Assay Description The biochemical activity of compounds was determined by incubation with specific enzymes and substrates in the presence ATP/[gamma-33P] ATP. After in...				J Med Chem 48: 2944-56 (2005) Article DOI: 10.1021/jm0408870 BindingDB Entry DOI: 10.7270/Q2WQ020R
					More data for this Ligand-Target Pair
Cell division cycle 7-related protein kinase (Homo sapiens (Human))	BDBM50329426 (5-(2-Amino-5-fluoro-pyrimidin-4-yl)-2-phenyl-1H-py...) Show SMILES NC(=O)c1cc([nH]c1-c1ccccc1)-c1nc(N)ncc1F Show InChI InChI=1S/C15H12FN5O/c16-10-7-19-15(18)21-13(10)11-6-9(14(17)22)12(20-11)8-4-2-1-3-5-8/h1-7,20H,(H2,17,22)(H2,18,19,21)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	18	n/a	n/a	n/a	n/a	n/a	n/a
Nerviano Medical Sciences Srl Curated by ChEMBL					Assay Description Inhibition of Cdc7				J Med Chem 53: 7296-315 (2010) Article DOI: 10.1021/jm100504d BindingDB Entry DOI: 10.7270/Q24T6JM3
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 9 (Homo sapiens (Human))	BDBM5655 (2-(2-chlorophenyl)-5,7-dihydroxy-8-[(3S,4R)-3-hydr...) Show SMILES CN1CC[C@@H]([C@H](O)C1)c1c(O)cc(O)c2c1oc(cc2=O)-c1ccccc1Cl |r| Show InChI InChI=1S/C21H20ClNO5/c1-23-7-6-12(17(27)10-23)19-14(24)8-15(25)20-16(26)9-18(28-21(19)20)11-4-2-3-5-13(11)22/h2-5,8-9,12,17,24-25,27H,6-7,10H2,1H3/t12-,17+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank MMDB PDB Article PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
Nerviano Medical Sciences Oncology Curated by ChEMBL					Assay Description Inhibition of cdk9				Nat Chem Biol 4: 357-65 (2008) Article DOI: 10.1038/nchembio.90 BindingDB Entry DOI: 10.7270/Q2DV1KVK
					More data for this Ligand-Target Pair				3D Structure (crystal)
Cyclin-A2/Cyclin-dependent kinase 2 (Homo sapiens (Human))	BDBM7103 (1-(4-{1-[(5-cyclopropyl-1H-pyrazol-3-yl)carbamoyl]...) Show SMILES CC(C(=O)Nc1cc(n[nH]1)C1CC1)c1ccc(cc1)N1CCC(C(N)=O)C1=O Show InChI InChI=1S/C20H23N5O3/c1-11(19(27)22-17-10-16(23-24-17)13-2-3-13)12-4-6-14(7-5-12)25-9-8-15(18(21)26)20(25)28/h4-7,10-11,13,15H,2-3,8-9H2,1H3,(H2,21,26)(H2,22,23,24,27)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	7.4	22
Nerviano Medical Sciences					Assay Description The biochemical activity of compounds was determined by incubation with specific enzymes and substrates in the presence ATP/[gamma-33P] ATP. After in...				J Med Chem 48: 2944-56 (2005) Article DOI: 10.1021/jm0408870 BindingDB Entry DOI: 10.7270/Q2WQ020R
					More data for this Ligand-Target Pair
Cyclin-A2/Cyclin-dependent kinase 2 (Homo sapiens (Human))	BDBM7120 ((2S)-N-(5-Cyclopropyl-1H-pyrazol-3-yl)-2-[4-(2-oxo...) Show SMILES C[C@H](C(=O)Nc1cc(n[nH]1)C1CC1)c1ccc(cc1)N1CCOC1=O |r| Show InChI InChI=1S/C18H20N4O3/c1-11(17(23)19-16-10-15(20-21-16)13-2-3-13)12-4-6-14(7-5-12)22-8-9-25-18(22)24/h4-7,10-11,13H,2-3,8-9H2,1H3,(H2,19,20,21,23)/t11-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
Nerviano Medical Sciences					Assay Description The biochemical activity of compounds was determined by incubation with specific enzymes and substrates in the presence ATP/[gamma-33P] ATP. After in...				J Med Chem 48: 2944-56 (2005) Article DOI: 10.1021/jm0408870 BindingDB Entry DOI: 10.7270/Q2WQ020R
					More data for this Ligand-Target Pair
Cyclin-A1/Cyclin-A2/Cyclin-dependent kinase 2 (Homo sapiens (Human))	BDBM50027398 (CHEMBL597992) Show SMILES CN1CCC(CC1)C(=O)N1Cc2c(NC(=O)NCc3ccccc3)n[nH]c2C1(C)C Show InChI InChI=1S/C22H30N6O2/c1-22(2)18-17(14-28(22)20(29)16-9-11-27(3)12-10-16)19(26-25-18)24-21(30)23-13-15-7-5-4-6-8-15/h4-8,16H,9-14H2,1-3H3,(H3,23,24,25,26,30)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	21	n/a	n/a	n/a	n/a	n/a	n/a
Nerviano Medical Sciences Srl Curated by ChEMBL					Assay Description Inhibition of human CDK2/cyclin A expressed in Escherichia coli BL21 by scintillation proximity assay				Bioorg Med Chem 18: 1844-53 (2010) Article DOI: 10.1016/j.bmc.2010.01.042 BindingDB Entry DOI: 10.7270/Q21R6RG5
					More data for this Ligand-Target Pair
Cell division cycle 7-related protein kinase (Homo sapiens (Human))	BDBM50329433 (5-(2-Amino-pyrimidin-4-yl)-2-thiophen-2-yl-1H-pyrr...) Show SMILES NC(=O)c1cc([nH]c1-c1cccs1)-c1ccnc(N)n1 Show InChI InChI=1S/C13H11N5OS/c14-12(19)7-6-9(8-3-4-16-13(15)18-8)17-11(7)10-2-1-5-20-10/h1-6,17H,(H2,14,19)(H2,15,16,18)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	22	n/a	n/a	n/a	n/a	n/a	n/a
Nerviano Medical Sciences Srl Curated by ChEMBL					Assay Description Inhibition of Cdc7				J Med Chem 53: 7296-315 (2010) Article DOI: 10.1021/jm100504d BindingDB Entry DOI: 10.7270/Q24T6JM3
					More data for this Ligand-Target Pair
Cell division cycle 7-related protein kinase (Homo sapiens (Human))	BDBM50329427 (5-(2-Amino-pyrimidin-4-yl)-2-phenyl-1H-pyrrole-3-c...) Show SMILES NC(=O)c1cc([nH]c1-c1ccccc1)-c1ccnc(N)n1 Show InChI InChI=1S/C15H13N5O/c16-14(21)10-8-12(11-6-7-18-15(17)20-11)19-13(10)9-4-2-1-3-5-9/h1-8,19H,(H2,16,21)(H2,17,18,20)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	22	n/a	n/a	n/a	n/a	n/a	n/a
Nerviano Medical Sciences Srl Curated by ChEMBL					Assay Description Inhibition of Cdc7				J Med Chem 53: 7296-315 (2010) Article DOI: 10.1021/jm100504d BindingDB Entry DOI: 10.7270/Q24T6JM3
					More data for this Ligand-Target Pair
Cell division cycle 7-related protein kinase (Homo sapiens (Human))	BDBM50329414 (2-(4-Methoxy-phenyl)-5-pyridin-4-yl-1H-pyrrole-3-c...) Show SMILES COc1ccc(cc1)-c1[nH]c(cc1C(N)=O)-c1ccncc1 Show InChI InChI=1S/C17H15N3O2/c1-22-13-4-2-12(3-5-13)16-14(17(18)21)10-15(20-16)11-6-8-19-9-7-11/h2-10,20H,1H3,(H2,18,21)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	23	n/a	n/a	n/a	n/a	n/a	n/a
Nerviano Medical Sciences Srl Curated by ChEMBL					Assay Description Inhibition of Cdc7				J Med Chem 53: 7296-315 (2010) Article DOI: 10.1021/jm100504d BindingDB Entry DOI: 10.7270/Q24T6JM3
					More data for this Ligand-Target Pair
Cyclin-A1/Cyclin-A2/Cyclin-dependent kinase 2 (Homo sapiens (Human))	BDBM50027417 (CHEMBL599237) Show SMILES CN1CCC(CC1)C(=O)N1Cc2c(NC(=O)c3ccc(F)cc3)n[nH]c2C1(C)C Show InChI InChI=1S/C21H26FN5O2/c1-21(2)17-16(12-27(21)20(29)14-8-10-26(3)11-9-14)18(25-24-17)23-19(28)13-4-6-15(22)7-5-13/h4-7,14H,8-12H2,1-3H3,(H2,23,24,25,28)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	23	n/a	n/a	n/a	n/a	n/a	n/a
Nerviano Medical Sciences Srl Curated by ChEMBL					Assay Description Inhibition of human CDK2/cyclin A expressed in Escherichia coli BL21 by scintillation proximity assay				Bioorg Med Chem 18: 1844-53 (2010) Article DOI: 10.1016/j.bmc.2010.01.042 BindingDB Entry DOI: 10.7270/Q21R6RG5
					More data for this Ligand-Target Pair
Cyclin-A1/Cyclin-A2/Cyclin-dependent kinase 2 (Homo sapiens (Human))	BDBM50027390 (CHEMBL606336) Show SMILES CN1CCC(CC1)C(=O)N1Cc2c(NC(=O)c3ccccc3)n[nH]c2C1(C)C Show InChI InChI=1S/C21H27N5O2/c1-21(2)17-16(13-26(21)20(28)15-9-11-25(3)12-10-15)18(24-23-17)22-19(27)14-7-5-4-6-8-14/h4-8,15H,9-13H2,1-3H3,(H2,22,23,24,27)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	23	n/a	n/a	n/a	n/a	n/a	n/a
Nerviano Medical Sciences Srl Curated by ChEMBL					Assay Description Inhibition of human CDK2/cyclin A expressed in Escherichia coli BL21 by scintillation proximity assay				Bioorg Med Chem 18: 1844-53 (2010) Article DOI: 10.1016/j.bmc.2010.01.042 BindingDB Entry DOI: 10.7270/Q21R6RG5
					More data for this Ligand-Target Pair
Cell division cycle 7-related protein kinase (Homo sapiens (Human))	BDBM50329425 (2-(3-Fluoro-phenyl)-5-pyridin-4-yl-1H-pyrrole-3-ca...) Show SMILES NC(=O)c1cc([nH]c1-c1cccc(F)c1)-c1ccncc1 Show InChI InChI=1S/C16H12FN3O/c17-12-3-1-2-11(8-12)15-13(16(18)21)9-14(20-15)10-4-6-19-7-5-10/h1-9,20H,(H2,18,21)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	23	n/a	n/a	n/a	n/a	n/a	n/a
Nerviano Medical Sciences Srl Curated by ChEMBL					Assay Description Inhibition of Cdc7				J Med Chem 53: 7296-315 (2010) Article DOI: 10.1021/jm100504d BindingDB Entry DOI: 10.7270/Q24T6JM3
					More data for this Ligand-Target Pair
Cyclin-A1/Cyclin-A2/Cyclin-dependent kinase 2 (Homo sapiens (Human))	BDBM50027420 (CHEMBL1744458) Show SMILES CC(C)CC(=O)Nc1n[nH]c2c1CN(C(=O)C1CCN(CC1)C1CC1)C2(C)C Show InChI InChI=1S/C21H33N5O2/c1-13(2)11-17(27)22-19-16-12-26(21(3,4)18(16)23-24-19)20(28)14-7-9-25(10-8-14)15-5-6-15/h13-15H,5-12H2,1-4H3,(H2,22,23,24,27)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	24	n/a	n/a	n/a	n/a	n/a	n/a
Nerviano Medical Sciences Srl Curated by ChEMBL					Assay Description Inhibition of human CDK2/cyclin A expressed in Escherichia coli BL21 by scintillation proximity assay				Bioorg Med Chem 18: 1844-53 (2010) Article DOI: 10.1016/j.bmc.2010.01.042 BindingDB Entry DOI: 10.7270/Q21R6RG5
					More data for this Ligand-Target Pair
Cyclin-A1/Cyclin-A2/Cyclin-dependent kinase 2 (Homo sapiens (Human))	BDBM50027402 (CHEMBL1744451) Show SMILES CN1CCC(CC1)C(=O)N1Cc2c(NC(=O)c3ccncc3)n[nH]c2C1(C)C Show InChI InChI=1S/C20H26N6O2/c1-20(2)16-15(12-26(20)19(28)14-6-10-25(3)11-7-14)17(24-23-16)22-18(27)13-4-8-21-9-5-13/h4-5,8-9,14H,6-7,10-12H2,1-3H3,(H2,22,23,24,27)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	25	n/a	n/a	n/a	n/a	n/a	n/a
Nerviano Medical Sciences Srl Curated by ChEMBL					Assay Description Inhibition of human CDK2/cyclin A expressed in Escherichia coli BL21 by scintillation proximity assay				Bioorg Med Chem 18: 1844-53 (2010) Article DOI: 10.1016/j.bmc.2010.01.042 BindingDB Entry DOI: 10.7270/Q21R6RG5
					More data for this Ligand-Target Pair
Cyclin-A1/Cyclin-A2/Cyclin-dependent kinase 2 (Homo sapiens (Human))	BDBM50027428 (CHEMBL603249) Show SMILES CN1CCC(CC1)C(=O)N1Cc2c(NC(=O)c3ccc(cc3)C(F)(F)F)n[nH]c2C1(C)C Show InChI InChI=1S/C22H26F3N5O2/c1-21(2)17-16(12-30(21)20(32)14-8-10-29(3)11-9-14)18(28-27-17)26-19(31)13-4-6-15(7-5-13)22(23,24)25/h4-7,14H,8-12H2,1-3H3,(H2,26,27,28,31)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	26	n/a	n/a	n/a	n/a	n/a	n/a
Nerviano Medical Sciences Srl Curated by ChEMBL					Assay Description Inhibition of human CDK2/cyclin A expressed in Escherichia coli BL21 by scintillation proximity assay				Bioorg Med Chem 18: 1844-53 (2010) Article DOI: 10.1016/j.bmc.2010.01.042 BindingDB Entry DOI: 10.7270/Q21R6RG5
					More data for this Ligand-Target Pair
Cyclin-A1/Cyclin-A2/Cyclin-dependent kinase 2 (Homo sapiens (Human))	BDBM50027412 (CHEMBL1744449) Show SMILES CN1CCC(CC1)C(=O)N1Cc2c(NC(=O)c3ccc4ccccc4c3)n[nH]c2C1(C)C Show InChI InChI=1S/C25H29N5O2/c1-25(2)21-20(15-30(25)24(32)17-10-12-29(3)13-11-17)22(28-27-21)26-23(31)19-9-8-16-6-4-5-7-18(16)14-19/h4-9,14,17H,10-13,15H2,1-3H3,(H2,26,27,28,31)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	27	n/a	n/a	n/a	n/a	n/a	n/a
Nerviano Medical Sciences Srl Curated by ChEMBL					Assay Description Inhibition of human CDK2/cyclin A expressed in Escherichia coli BL21 by scintillation proximity assay				Bioorg Med Chem 18: 1844-53 (2010) Article DOI: 10.1016/j.bmc.2010.01.042 BindingDB Entry DOI: 10.7270/Q21R6RG5
					More data for this Ligand-Target Pair
Cyclin-A1/Cyclin-A2/Cyclin-dependent kinase 2 (Homo sapiens (Human))	BDBM50027414 (CHEMBL606187) Show SMILES CC1(C)N(Cc2c(NC(=O)c3ccc(F)cc3)n[nH]c12)C(=O)C1CCNCC1 Show InChI InChI=1S/C20H24FN5O2/c1-20(2)16-15(11-26(20)19(28)13-7-9-22-10-8-13)17(25-24-16)23-18(27)12-3-5-14(21)6-4-12/h3-6,13,22H,7-11H2,1-2H3,(H2,23,24,25,27)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
Nerviano Medical Sciences Srl Curated by ChEMBL					Assay Description Inhibition of human CDK2/cyclin A expressed in Escherichia coli BL21 by scintillation proximity assay				Bioorg Med Chem 18: 1844-53 (2010) Article DOI: 10.1016/j.bmc.2010.01.042 BindingDB Entry DOI: 10.7270/Q21R6RG5
					More data for this Ligand-Target Pair
Cyclin-A1/Cyclin-A2/Cyclin-dependent kinase 2 (Homo sapiens (Human))	BDBM50027429 (CHEMBL603543) Show SMILES CCN1CCC(CC1)C(=O)N1Cc2c(NC(=O)c3ccc(F)cc3)n[nH]c2C1(C)C Show InChI InChI=1S/C22H28FN5O2/c1-4-27-11-9-15(10-12-27)21(30)28-13-17-18(22(28,2)3)25-26-19(17)24-20(29)14-5-7-16(23)8-6-14/h5-8,15H,4,9-13H2,1-3H3,(H2,24,25,26,29)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
Nerviano Medical Sciences Srl Curated by ChEMBL					Assay Description Inhibition of human CDK2/cyclin A expressed in Escherichia coli BL21 by scintillation proximity assay				Bioorg Med Chem 18: 1844-53 (2010) Article DOI: 10.1016/j.bmc.2010.01.042 BindingDB Entry DOI: 10.7270/Q21R6RG5
					More data for this Ligand-Target Pair
Cyclin-A1/Cyclin-A2/Cyclin-dependent kinase 2 (Homo sapiens (Human))	BDBM50027400 (CHEMBL597390) Show SMILES CC(C)(C)C(=O)N1Cc2c(NC(=O)c3ccc(F)cc3)n[nH]c2C1(C)C Show InChI InChI=1S/C19H23FN4O2/c1-18(2,3)17(26)24-10-13-14(19(24,4)5)22-23-15(13)21-16(25)11-6-8-12(20)9-7-11/h6-9H,10H2,1-5H3,(H2,21,22,23,25)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
Nerviano Medical Sciences Srl Curated by ChEMBL					Assay Description Inhibition of human CDK2/cyclin A expressed in Escherichia coli BL21 by scintillation proximity assay				Bioorg Med Chem 18: 1844-53 (2010) Article DOI: 10.1016/j.bmc.2010.01.042 BindingDB Entry DOI: 10.7270/Q21R6RG5
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 1 (Homo sapiens (Human))	BDBM5655 (2-(2-chlorophenyl)-5,7-dihydroxy-8-[(3S,4R)-3-hydr...) Show SMILES CN1CC[C@@H]([C@H](O)C1)c1c(O)cc(O)c2c1oc(cc2=O)-c1ccccc1Cl |r| Show InChI InChI=1S/C21H20ClNO5/c1-23-7-6-12(17(27)10-23)19-14(24)8-15(25)20-16(26)9-18(28-21(19)20)11-4-2-3-5-13(11)22/h2-5,8-9,12,17,24-25,27H,6-7,10H2,1H3/t12-,17+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank Article PubMed	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
Nerviano Medical Sciences Oncology Curated by ChEMBL					Assay Description Inhibition of cdk1				Nat Chem Biol 4: 357-65 (2008) Article DOI: 10.1038/nchembio.90 BindingDB Entry DOI: 10.7270/Q2DV1KVK
					More data for this Ligand-Target Pair
Cyclin-A1/Cyclin-A2/Cyclin-dependent kinase 2 (Homo sapiens (Human))	BDBM50027425 (CHEMBL1744454) Show SMILES CN1CCC(CC1)C(=O)N1Cc2c(NC(=O)c3ccco3)n[nH]c2C1(C)C Show InChI InChI=1S/C19H25N5O3/c1-19(2)15-13(11-24(19)18(26)12-6-8-23(3)9-7-12)16(22-21-15)20-17(25)14-5-4-10-27-14/h4-5,10,12H,6-9,11H2,1-3H3,(H2,20,21,22,25)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	33	n/a	n/a	n/a	n/a	n/a	n/a
Nerviano Medical Sciences Srl Curated by ChEMBL					Assay Description Inhibition of human CDK2/cyclin A expressed in Escherichia coli BL21 by scintillation proximity assay				Bioorg Med Chem 18: 1844-53 (2010) Article DOI: 10.1016/j.bmc.2010.01.042 BindingDB Entry DOI: 10.7270/Q21R6RG5
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 9 (Homo sapiens (Human))	BDBM27344 (2-(pyridin-4-yl)-1H,4H,5H,6H,7H-pyrrolo[3,2-c]pyri...) Show SMILES O=C1NCCc2[nH]c(cc12)-c1ccncc1 Show InChI InChI=1S/C12H11N3O/c16-12-9-7-11(8-1-4-13-5-2-8)15-10(9)3-6-14-12/h1-2,4-5,7,15H,3,6H2,(H,14,16)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	34	n/a	n/a	n/a	n/a	n/a	n/a
Nerviano Medical Sciences Oncology Curated by ChEMBL					Assay Description Inhibition of cdk9				Nat Chem Biol 4: 357-65 (2008) Article DOI: 10.1038/nchembio.90 BindingDB Entry DOI: 10.7270/Q2DV1KVK
					More data for this Ligand-Target Pair

Displayed 1 to 50 (of 290 total )  |  Next  |  Last  >>

Jump to: