Compile Data Set for Download or QSAR

Found 47 hits with Last Name = 'kwong' and Initial = 'cd'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Epidermal growth factor receptor/Receptor tyrosine-protein kinase erbB-2 (Homo sapiens (Human))	BDBM50289961 (CHEMBL65376 | Pentanedioic acid furan-2-ylmethyl e...) Show SMILES [O-][N+](=O)\C=C\c1ccc(OC(=O)CCCC(=O)OCc2ccco2)cc1 Show InChI InChI=1S/C18H17NO7/c20-17(25-13-16-3-2-12-24-16)4-1-5-18(21)26-15-8-6-14(7-9-15)10-11-19(22)23/h2-3,6-12H,1,4-5,13H2/b11-10+	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article	n/a	n/a	290	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of ligand-stimulated autophosphorylation of EGFR/HER2 chimeric receptor expressed in NIH3T3 cells				Bioorg Med Chem Lett 7: 2109-2114 (1997) Article DOI: 10.1016/S0960-894X(97)00369-7 BindingDB Entry DOI: 10.7270/Q2N016H3
					More data for this Ligand-Target Pair
Epidermal growth factor receptor/Receptor tyrosine-protein kinase erbB-2 (Homo sapiens (Human))	BDBM50289957 (CHEMBL304442 | Pentanedioic acid 4-((E)-2-nitro-vi...) Show SMILES [O-][N+](=O)\C=C\c1ccc(OC(=O)CCCC(=O)Oc2ccccc2)cc1 Show InChI InChI=1S/C19H17NO6/c21-18(25-16-5-2-1-3-6-16)7-4-8-19(22)26-17-11-9-15(10-12-17)13-14-20(23)24/h1-3,5-6,9-14H,4,7-8H2/b14-13+	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	420	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of ligand-stimulated autophosphorylation of EGFR/HER2 chimeric receptor expressed in NIH3T3 cells				Bioorg Med Chem Lett 7: 2109-2114 (1997) Article DOI: 10.1016/S0960-894X(97)00369-7 BindingDB Entry DOI: 10.7270/Q2N016H3
					More data for this Ligand-Target Pair
Epidermal growth factor receptor/Receptor tyrosine-protein kinase erbB-2 (Homo sapiens (Human))	BDBM50289964 (CHEMBL63559 | Pentanedioic acid 4-methoxy-phenyl e...) Show SMILES COc1ccc(OC(=O)CCCC(=O)Oc2ccc(\C=C\[N+]([O-])=O)cc2)cc1 Show InChI InChI=1S/C20H19NO7/c1-26-16-9-11-18(12-10-16)28-20(23)4-2-3-19(22)27-17-7-5-15(6-8-17)13-14-21(24)25/h5-14H,2-4H2,1H3/b14-13+	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of ligand-stimulated autophosphorylation of EGFR/HER2 chimeric receptor expressed in NIH3T3 cells				Bioorg Med Chem Lett 7: 2109-2114 (1997) Article DOI: 10.1016/S0960-894X(97)00369-7 BindingDB Entry DOI: 10.7270/Q2N016H3
					More data for this Ligand-Target Pair
DNA topoisomerase 1 (Homo sapiens (Human))	BDBM50203110 (CHEMBL3914791) Show SMILES [I-].C[n+]1c2-c3ccccc3-c3nc(cc(c23)c2ccccc12)-c1ccccc1 Show InChI InChI=1S/C25H17N2/c1-27-22-14-8-7-11-17(22)20-15-21(16-9-3-2-4-10-16)26-24-18-12-5-6-13-19(18)25(27)23(20)24/h2-15H,1H3/q+1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Southern Research Institute Curated by ChEMBL					Assay Description Inhibition of human DNA topoisomerase 1 using pHOT1 as substrate after 30 mins by agarose gel electrophoresis				Bioorg Med Chem 24: 6119-6130 (2016) Article DOI: 10.1016/j.bmc.2016.02.028 BindingDB Entry DOI: 10.7270/Q2BG2QZJ
					More data for this Ligand-Target Pair
DNA topoisomerase 1 (Homo sapiens (Human))	BDBM50203111 (CHEMBL3968023) Show SMILES [I-].C[n+]1ccc2c3c(nc4cc5OCOc5cc24)-c2ccccc2-c13 Show InChI InChI=1S/C20H13N2O2/c1-22-7-6-11-14-8-16-17(24-10-23-16)9-15(14)21-19-12-4-2-3-5-13(12)20(22)18(11)19/h2-9H,10H2,1H3/q+1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.02E+3	n/a	n/a	n/a	n/a	n/a	n/a
Southern Research Institute Curated by ChEMBL					Assay Description Inhibition of human DNA topoisomerase 1 using pHOT1 as substrate after 30 mins by agarose gel electrophoresis				Bioorg Med Chem 24: 6119-6130 (2016) Article DOI: 10.1016/j.bmc.2016.02.028 BindingDB Entry DOI: 10.7270/Q2BG2QZJ
					More data for this Ligand-Target Pair
DNA topoisomerase 1 (Homo sapiens (Human))	BDBM50203043 (CHEMBL3896867) Show SMILES [Br-].C(c1ccccc1)[n+]1ccc2c3c(nc4cc5OCOc5cc24)-c2ccccc2-c13 Show InChI InChI=1S/C26H17N2O2/c1-2-6-16(7-3-1)14-28-11-10-17-20-12-22-23(30-15-29-22)13-21(20)27-25-18-8-4-5-9-19(18)26(28)24(17)25/h1-13H,14-15H2/q+1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Southern Research Institute Curated by ChEMBL					Assay Description Inhibition of human DNA topoisomerase 1 using pHOT1 as substrate after 30 mins by agarose gel electrophoresis				Bioorg Med Chem 24: 6119-6130 (2016) Article DOI: 10.1016/j.bmc.2016.02.028 BindingDB Entry DOI: 10.7270/Q2BG2QZJ
					More data for this Ligand-Target Pair
DNA topoisomerase 1 (Homo sapiens (Human))	BDBM50203113 (CHEMBL3889816) Show SMILES [Br-].C(c1ccccc1)[n+]1ccc2c3c(nc4ccccc24)-c2ccccc2-c13 Show InChI InChI=1S/C25H17N2/c1-2-8-17(9-3-1)16-27-15-14-19-18-10-6-7-13-22(18)26-24-20-11-4-5-12-21(20)25(27)23(19)24/h1-15H,16H2/q+1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.34E+3	n/a	n/a	n/a	n/a	n/a	n/a
Southern Research Institute Curated by ChEMBL					Assay Description Inhibition of human DNA topoisomerase 1 using pHOT1 as substrate after 30 mins by agarose gel electrophoresis				Bioorg Med Chem 24: 6119-6130 (2016) Article DOI: 10.1016/j.bmc.2016.02.028 BindingDB Entry DOI: 10.7270/Q2BG2QZJ
					More data for this Ligand-Target Pair
DNA topoisomerase 1 (Homo sapiens (Human))	BDBM50202837 (CHEMBL3941751) Show SMILES Cc1ccc(cc1)S([O-])(=O)=O.C[n+]1ccc2c3c(nc4ccccc24)-c2ccccc2-c13 Show InChI InChI=1S/C19H13N2/c1-21-11-10-13-12-6-4-5-9-16(12)20-18-14-7-2-3-8-15(14)19(21)17(13)18/h2-11H,1H3/q+1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.58E+3	n/a	n/a	n/a	n/a	n/a	n/a
Southern Research Institute Curated by ChEMBL					Assay Description Inhibition of human DNA topoisomerase 1 using pHOT1 as substrate after 30 mins by agarose gel electrophoresis				Bioorg Med Chem 24: 6119-6130 (2016) Article DOI: 10.1016/j.bmc.2016.02.028 BindingDB Entry DOI: 10.7270/Q2BG2QZJ
					More data for this Ligand-Target Pair
DNA topoisomerase 1 (Homo sapiens (Human))	BDBM50203040 (CHEMBL3932774) Show SMILES [I-].CC[n+]1ccc2c3c(nc4ccccc24)-c2ccccc2-c13 Show InChI InChI=1S/C20H15N2/c1-2-22-12-11-14-13-7-5-6-10-17(13)21-19-15-8-3-4-9-16(15)20(22)18(14)19/h3-12H,2H2,1H3/q+1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
Southern Research Institute Curated by ChEMBL					Assay Description Inhibition of human DNA topoisomerase 1 using pHOT1 as substrate after 30 mins by agarose gel electrophoresis				Bioorg Med Chem 24: 6119-6130 (2016) Article DOI: 10.1016/j.bmc.2016.02.028 BindingDB Entry DOI: 10.7270/Q2BG2QZJ
					More data for this Ligand-Target Pair
DNA topoisomerase 1 (Homo sapiens (Human))	BDBM50203048 (CHEMBL3984603) Show SMILES [I-].Cc1cc2c3c(nc4ccccc24)-c2ccccc2-c3[n+]1C Show InChI InChI=1S/C20H15N2/c1-12-11-16-13-7-5-6-10-17(13)21-19-14-8-3-4-9-15(14)20(18(16)19)22(12)2/h3-11H,1-2H3/q+1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
Southern Research Institute Curated by ChEMBL					Assay Description Inhibition of human DNA topoisomerase 1 using pHOT1 as substrate after 30 mins by agarose gel electrophoresis				Bioorg Med Chem 24: 6119-6130 (2016) Article DOI: 10.1016/j.bmc.2016.02.028 BindingDB Entry DOI: 10.7270/Q2BG2QZJ
					More data for this Ligand-Target Pair
Epidermal growth factor receptor/Receptor tyrosine-protein kinase erbB-2 (Homo sapiens (Human))	BDBM50289963 (CHEMBL3142195 | CHEMBL92506 | Pentanedioic acid (2...) Show SMILES CC(C)O[C@@H]1[C@@H](COC(=O)CCCC(=O)Oc2ccc(\C=C\[N+]([O-])=O)cc2)O[C@H]([C@@H]1OC(C)C)n1cnc2c(N)ncnc12 |r| Show InChI InChI=1S/C29H36N6O9/c1-17(2)41-25-21(44-29(26(25)42-18(3)4)34-16-33-24-27(30)31-15-32-28(24)34)14-40-22(36)6-5-7-23(37)43-20-10-8-19(9-11-20)12-13-35(38)39/h8-13,15-18,21,25-26,29H,5-7,14H2,1-4H3,(H2,30,31,32)/b13-12+	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article	n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of ligand-stimulated autophosphorylation of EGFR/HER2 chimeric receptor expressed in NIH3T3 cells				Bioorg Med Chem Lett 7: 2109-2114 (1997) Article DOI: 10.1016/S0960-894X(97)00369-7 BindingDB Entry DOI: 10.7270/Q2N016H3
					More data for this Ligand-Target Pair
Receptor tyrosine-protein kinase erbB-2 (Homo sapiens (Human))	BDBM50289961 (CHEMBL65376 | Pentanedioic acid furan-2-ylmethyl e...) Show SMILES [O-][N+](=O)\C=C\c1ccc(OC(=O)CCCC(=O)OCc2ccco2)cc1 Show InChI InChI=1S/C18H17NO7/c20-17(25-13-16-3-2-12-24-16)4-1-5-18(21)26-15-8-6-14(7-9-15)10-11-19(22)23/h2-3,6-12H,1,4-5,13H2/b11-10+	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article	n/a	n/a	3.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of autophosphorylation of HER-2 expressed in NIH3T3 cell lines				Bioorg Med Chem Lett 7: 2109-2114 (1997) Article DOI: 10.1016/S0960-894X(97)00369-7 BindingDB Entry DOI: 10.7270/Q2N016H3
					More data for this Ligand-Target Pair
Receptor tyrosine-protein kinase erbB-2 (Homo sapiens (Human))	BDBM50289957 (CHEMBL304442 | Pentanedioic acid 4-((E)-2-nitro-vi...) Show SMILES [O-][N+](=O)\C=C\c1ccc(OC(=O)CCCC(=O)Oc2ccccc2)cc1 Show InChI InChI=1S/C19H17NO6/c21-18(25-16-5-2-1-3-6-16)7-4-8-19(22)26-17-11-9-15(10-12-17)13-14-20(23)24/h1-3,5-6,9-14H,4,7-8H2/b14-13+	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	4.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of autophosphorylation of HER-2 expressed in NIH3T3 cell lines				Bioorg Med Chem Lett 7: 2109-2114 (1997) Article DOI: 10.1016/S0960-894X(97)00369-7 BindingDB Entry DOI: 10.7270/Q2N016H3
					More data for this Ligand-Target Pair
Receptor tyrosine-protein kinase erbB-2 (Homo sapiens (Human))	BDBM50289963 (CHEMBL3142195 | CHEMBL92506 | Pentanedioic acid (2...) Show SMILES CC(C)O[C@@H]1[C@@H](COC(=O)CCCC(=O)Oc2ccc(\C=C\[N+]([O-])=O)cc2)O[C@H]([C@@H]1OC(C)C)n1cnc2c(N)ncnc12 |r| Show InChI InChI=1S/C29H36N6O9/c1-17(2)41-25-21(44-29(26(25)42-18(3)4)34-16-33-24-27(30)31-15-32-28(24)34)14-40-22(36)6-5-7-23(37)43-20-10-8-19(9-11-20)12-13-35(38)39/h8-13,15-18,21,25-26,29H,5-7,14H2,1-4H3,(H2,30,31,32)/b13-12+	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article	n/a	n/a	4.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of autophosphorylation of HER-2 expressed in NIH3T3 cell lines				Bioorg Med Chem Lett 7: 2109-2114 (1997) Article DOI: 10.1016/S0960-894X(97)00369-7 BindingDB Entry DOI: 10.7270/Q2N016H3
					More data for this Ligand-Target Pair
DNA topoisomerase 1 (Homo sapiens (Human))	BDBM50202840 (CHEMBL3904763) Show SMILES [I-].C[n+]1ccc2c3c(nc4ccccc24)-c2ccccc2-c13 Show InChI InChI=1S/C19H13N2/c1-21-11-10-13-12-6-4-5-9-16(12)20-18-14-7-2-3-8-15(14)19(21)17(13)18/h2-11H,1H3/q+1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.54E+3	n/a	n/a	n/a	n/a	n/a	n/a
Southern Research Institute Curated by ChEMBL					Assay Description Inhibition of human DNA topoisomerase 1 using pHOT1 as substrate after 30 mins by agarose gel electrophoresis				Bioorg Med Chem 24: 6119-6130 (2016) Article DOI: 10.1016/j.bmc.2016.02.028 BindingDB Entry DOI: 10.7270/Q2BG2QZJ
					More data for this Ligand-Target Pair
Epidermal growth factor receptor/Receptor tyrosine-protein kinase erbB-2 (Homo sapiens (Human))	BDBM50214741 (CHEMBL65096) Show SMILES [O-][N+](=O)\C=C\c1ccc(OC(=O)CCCC(=O)NCc2ccccc2)cc1 Show InChI InChI=1S/C20H20N2O5/c23-19(21-15-17-5-2-1-3-6-17)7-4-8-20(24)27-18-11-9-16(10-12-18)13-14-22(25)26/h1-3,5-6,9-14H,4,7-8,15H2,(H,21,23)/b14-13+	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	4.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of ligand-stimulated autophosphorylation of EGFR/HER2 chimeric receptor expressed in NIH3T3 cells				Bioorg Med Chem Lett 7: 2109-2114 (1997) Article DOI: 10.1016/S0960-894X(97)00369-7 BindingDB Entry DOI: 10.7270/Q2N016H3
					More data for this Ligand-Target Pair
DNA topoisomerase 1 (Homo sapiens (Human))	BDBM50203042 (CHEMBL3923820) Show SMILES [Br-].CCOC(=O)C[n+]1ccc2c3c(nc4ccccc24)-c2ccccc2-c13 Show InChI InChI=1S/C22H17N2O2/c1-2-26-19(25)13-24-12-11-15-14-7-5-6-10-18(14)23-21-16-8-3-4-9-17(16)22(24)20(15)21/h3-12H,2,13H2,1H3/q+1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.69E+3	n/a	n/a	n/a	n/a	n/a	n/a
Southern Research Institute Curated by ChEMBL					Assay Description Inhibition of human DNA topoisomerase 1 using pHOT1 as substrate after 30 mins by agarose gel electrophoresis				Bioorg Med Chem 24: 6119-6130 (2016) Article DOI: 10.1016/j.bmc.2016.02.028 BindingDB Entry DOI: 10.7270/Q2BG2QZJ
					More data for this Ligand-Target Pair
Receptor tyrosine-protein kinase erbB-2 (Homo sapiens (Human))	BDBM50289964 (CHEMBL63559 | Pentanedioic acid 4-methoxy-phenyl e...) Show SMILES COc1ccc(OC(=O)CCCC(=O)Oc2ccc(\C=C\[N+]([O-])=O)cc2)cc1 Show InChI InChI=1S/C20H19NO7/c1-26-16-9-11-18(12-10-16)28-20(23)4-2-3-19(22)27-17-7-5-15(6-8-17)13-14-21(24)25/h5-14H,2-4H2,1H3/b14-13+	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	6.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of autophosphorylation of HER-2 expressed in NIH3T3 cell lines				Bioorg Med Chem Lett 7: 2109-2114 (1997) Article DOI: 10.1016/S0960-894X(97)00369-7 BindingDB Entry DOI: 10.7270/Q2N016H3
					More data for this Ligand-Target Pair
Epidermal growth factor receptor/Receptor tyrosine-protein kinase erbB-2 (Homo sapiens (Human))	BDBM50214742 (CHEMBL302905) Show SMILES COc1cccc(OC(=O)CCCC(=O)Oc2ccc(\C=C\[N+]([O-])=O)cc2)c1 Show InChI InChI=1S/C20H19NO7/c1-26-17-4-2-5-18(14-17)28-20(23)7-3-6-19(22)27-16-10-8-15(9-11-16)12-13-21(24)25/h2,4-5,8-14H,3,6-7H2,1H3/b13-12+	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article	n/a	n/a	9.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of ligand-stimulated autophosphorylation of EGFR/HER2 chimeric receptor expressed in NIH3T3 cells				Bioorg Med Chem Lett 7: 2109-2114 (1997) Article DOI: 10.1016/S0960-894X(97)00369-7 BindingDB Entry DOI: 10.7270/Q2N016H3
					More data for this Ligand-Target Pair
DNA topoisomerase 1 (Homo sapiens (Human))	BDBM50203044 (CHEMBL3960953) Show SMILES [Br-].C(c1ccccc1)[n+]1ccc2cc(nc3-c4ccccc4-c1c23)-c1ccccc1 Show InChI InChI=1S/C27H19N2/c1-3-9-19(10-4-1)18-29-16-15-21-17-24(20-11-5-2-6-12-20)28-26-22-13-7-8-14-23(22)27(29)25(21)26/h1-17H,18H2/q+1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	9.74E+3	n/a	n/a	n/a	n/a	n/a	n/a
Southern Research Institute Curated by ChEMBL					Assay Description Inhibition of human DNA topoisomerase 1 using pHOT1 as substrate after 30 mins by agarose gel electrophoresis				Bioorg Med Chem 24: 6119-6130 (2016) Article DOI: 10.1016/j.bmc.2016.02.028 BindingDB Entry DOI: 10.7270/Q2BG2QZJ
					More data for this Ligand-Target Pair
Epidermal growth factor receptor/Receptor tyrosine-protein kinase erbB-2 (Homo sapiens (Human))	BDBM50214738 (CHEMBL65594) Show SMILES [O-][N+](=O)\C=C\c1ccc(OC(=O)CCCC(=O)Nc2ccccc2)cc1 Show InChI InChI=1S/C19H18N2O5/c22-18(20-16-5-2-1-3-6-16)7-4-8-19(23)26-17-11-9-15(10-12-17)13-14-21(24)25/h1-3,5-6,9-14H,4,7-8H2,(H,20,22)/b14-13+	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of ligand-stimulated autophosphorylation of EGFR/HER2 chimeric receptor expressed in NIH3T3 cells				Bioorg Med Chem Lett 7: 2109-2114 (1997) Article DOI: 10.1016/S0960-894X(97)00369-7 BindingDB Entry DOI: 10.7270/Q2N016H3
					More data for this Ligand-Target Pair
Epidermal growth factor receptor/Receptor tyrosine-protein kinase erbB-2 (Homo sapiens (Human))	BDBM50214739 (CHEMBL68413) Show SMILES COc1ccccc1OC(=O)CCCC(=O)Oc1ccc(\C=C\[N+]([O-])=O)cc1 Show InChI InChI=1S/C20H19NO7/c1-26-17-5-2-3-6-18(17)28-20(23)8-4-7-19(22)27-16-11-9-15(10-12-16)13-14-21(24)25/h2-3,5-6,9-14H,4,7-8H2,1H3/b14-13+	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of ligand-stimulated autophosphorylation of EGFR/HER2 chimeric receptor expressed in NIH3T3 cells				Bioorg Med Chem Lett 7: 2109-2114 (1997) Article DOI: 10.1016/S0960-894X(97)00369-7 BindingDB Entry DOI: 10.7270/Q2N016H3
					More data for this Ligand-Target Pair
Epidermal growth factor receptor/Receptor tyrosine-protein kinase erbB-2 (Homo sapiens (Human))	BDBM50214743 (CHEMBL63650) Show SMILES [O-][N+](=O)\C=C\c1ccc(OC(=O)CCCC(=O)Oc2ccc(F)cc2)cc1 Show InChI InChI=1S/C19H16FNO6/c20-15-6-10-17(11-7-15)27-19(23)3-1-2-18(22)26-16-8-4-14(5-9-16)12-13-21(24)25/h4-13H,1-3H2/b13-12+	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of ligand-stimulated autophosphorylation of EGFR/HER2 chimeric receptor expressed in NIH3T3 cells				Bioorg Med Chem Lett 7: 2109-2114 (1997) Article DOI: 10.1016/S0960-894X(97)00369-7 BindingDB Entry DOI: 10.7270/Q2N016H3
					More data for this Ligand-Target Pair
Epidermal growth factor receptor/Receptor tyrosine-protein kinase erbB-2 (Homo sapiens (Human))	BDBM50214740 (CHEMBL67009) Show SMILES [O-][N+](=O)\C=C\c1ccc(OC(=O)CCCC(=O)OCc2ccccc2)cc1 Show InChI InChI=1S/C20H19NO6/c22-19(26-15-17-5-2-1-3-6-17)7-4-8-20(23)27-18-11-9-16(10-12-18)13-14-21(24)25/h1-3,5-6,9-14H,4,7-8,15H2/b14-13+	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of ligand-stimulated autophosphorylation of EGFR/HER2 chimeric receptor expressed in NIH3T3 cells				Bioorg Med Chem Lett 7: 2109-2114 (1997) Article DOI: 10.1016/S0960-894X(97)00369-7 BindingDB Entry DOI: 10.7270/Q2N016H3
					More data for this Ligand-Target Pair
Epidermal growth factor receptor/Receptor tyrosine-protein kinase erbB-2 (Homo sapiens (Human))	BDBM50214737 (CHEMBL63772) Show SMILES [O-][N+](=O)\C=C\c1ccc(OC(=O)CCCC(=O)OCCc2ccccc2)cc1 Show InChI InChI=1S/C21H21NO6/c23-20(27-16-14-17-5-2-1-3-6-17)7-4-8-21(24)28-19-11-9-18(10-12-19)13-15-22(25)26/h1-3,5-6,9-13,15H,4,7-8,14,16H2/b15-13+	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of ligand-stimulated autophosphorylation of EGFR/HER2 chimeric receptor expressed in NIH3T3 cells				Bioorg Med Chem Lett 7: 2109-2114 (1997) Article DOI: 10.1016/S0960-894X(97)00369-7 BindingDB Entry DOI: 10.7270/Q2N016H3
					More data for this Ligand-Target Pair
DNA topoisomerase 1 (Homo sapiens (Human))	BDBM50202835 (CHEMBL3895295) Show SMILES [Br-].COc1ccc-2c(c1)-c1[n+](Cc3ccccc3)ccc3ccnc-2c13 Show InChI InChI=1S/C22H17N2O/c1-25-17-7-8-18-19(13-17)22-20-16(9-11-23-21(18)20)10-12-24(22)14-15-5-3-2-4-6-15/h2-13H,14H2,1H3/q+1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.23E+4	n/a	n/a	n/a	n/a	n/a	n/a
Southern Research Institute Curated by ChEMBL					Assay Description Inhibition of human DNA topoisomerase 1 using pHOT1 as substrate after 30 mins by agarose gel electrophoresis				Bioorg Med Chem 24: 6119-6130 (2016) Article DOI: 10.1016/j.bmc.2016.02.028 BindingDB Entry DOI: 10.7270/Q2BG2QZJ
					More data for this Ligand-Target Pair
DNA topoisomerase 1 (Homo sapiens (Human))	BDBM50203049 (CHEMBL3904207) Show SMILES [I-].Cc1cc2cc[n+](C)c3-c4ccccc4-c(n1)c23 Show InChI InChI=1S/C16H13N2/c1-10-9-11-7-8-18(2)16-13-6-4-3-5-12(13)15(17-10)14(11)16/h3-9H,1-2H3/q+1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.24E+4	n/a	n/a	n/a	n/a	n/a	n/a
Southern Research Institute Curated by ChEMBL					Assay Description Inhibition of human DNA topoisomerase 1 using pHOT1 as substrate after 30 mins by agarose gel electrophoresis				Bioorg Med Chem 24: 6119-6130 (2016) Article DOI: 10.1016/j.bmc.2016.02.028 BindingDB Entry DOI: 10.7270/Q2BG2QZJ
					More data for this Ligand-Target Pair
DNA topoisomerase 1 (Homo sapiens (Human))	BDBM50203041 (CHEMBL3895818) Show SMILES [Br-].CC[n+]1c2-c3ccccc3-c3nc(cc(c23)c2ccccc12)-c1ccccc1 Show InChI InChI=1S/C26H19N2/c1-2-28-23-15-9-8-12-18(23)21-16-22(17-10-4-3-5-11-17)27-25-19-13-6-7-14-20(19)26(28)24(21)25/h3-16H,2H2,1H3/q+1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	<1.36E+4	n/a	n/a	n/a	n/a	n/a	n/a
Southern Research Institute Curated by ChEMBL					Assay Description Inhibition of human DNA topoisomerase 1 using pHOT1 as substrate after 30 mins by agarose gel electrophoresis				Bioorg Med Chem 24: 6119-6130 (2016) Article DOI: 10.1016/j.bmc.2016.02.028 BindingDB Entry DOI: 10.7270/Q2BG2QZJ
					More data for this Ligand-Target Pair
DNA topoisomerase 1 (Homo sapiens (Human))	BDBM50202838 (CHEBI:67605 | Eupolauridine) Show SMILES c1ccc-2c(c1)-c1nccc3ccnc-2c13 Show InChI InChI=1S/C14H8N2/c1-2-4-11-10(3-1)13-12-9(5-7-15-13)6-8-16-14(11)12/h1-8H	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.05E+4	n/a	n/a	n/a	n/a	n/a	n/a
Southern Research Institute Curated by ChEMBL					Assay Description Inhibition of human DNA topoisomerase 1 using pHOT1 as substrate after 30 mins by agarose gel electrophoresis				Bioorg Med Chem 24: 6119-6130 (2016) Article DOI: 10.1016/j.bmc.2016.02.028 BindingDB Entry DOI: 10.7270/Q2BG2QZJ
					More data for this Ligand-Target Pair
DNA topoisomerase 1 (Homo sapiens (Human))	BDBM50202880 (CHEMBL3914880) Show SMILES [Br-].Cc1ccc(C[n+]2ccc3ccnc4-c5ccccc5-c2c34)cc1 Show InChI InChI=1S/C22H17N2/c1-15-6-8-16(9-7-15)14-24-13-11-17-10-12-23-21-18-4-2-3-5-19(18)22(24)20(17)21/h2-13H,14H2,1H3/q+1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.82E+4	n/a	n/a	n/a	n/a	n/a	n/a
Southern Research Institute Curated by ChEMBL					Assay Description Inhibition of human DNA topoisomerase 1 using pHOT1 as substrate after 30 mins by agarose gel electrophoresis				Bioorg Med Chem 24: 6119-6130 (2016) Article DOI: 10.1016/j.bmc.2016.02.028 BindingDB Entry DOI: 10.7270/Q2BG2QZJ
					More data for this Ligand-Target Pair
DNA topoisomerase 1 (Homo sapiens (Human))	BDBM50203046 (CHEMBL3913215) Show SMILES [I-].C[n+]1ccc2cc(nc3-c4ccccc4-c1c23)-c1ccccc1 Show InChI InChI=1S/C21H15N2/c1-23-12-11-15-13-18(14-7-3-2-4-8-14)22-20-16-9-5-6-10-17(16)21(23)19(15)20/h2-13H,1H3/q+1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.84E+4	n/a	n/a	n/a	n/a	n/a	n/a
Southern Research Institute Curated by ChEMBL					Assay Description Inhibition of human DNA topoisomerase 1 using pHOT1 as substrate after 30 mins by agarose gel electrophoresis				Bioorg Med Chem 24: 6119-6130 (2016) Article DOI: 10.1016/j.bmc.2016.02.028 BindingDB Entry DOI: 10.7270/Q2BG2QZJ
					More data for this Ligand-Target Pair
DNA topoisomerase 1 (Homo sapiens (Human))	BDBM50202841 (CHEMBL3972163) Show SMILES [I-].C[n+]1ccc2ccnc3-c4ccccc4-c1c23 Show InChI InChI=1S/C15H11N2/c1-17-9-7-10-6-8-16-14-11-4-2-3-5-12(11)15(17)13(10)14/h2-9H,1H3/q+1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.88E+4	n/a	n/a	n/a	n/a	n/a	n/a
Southern Research Institute Curated by ChEMBL					Assay Description Inhibition of human DNA topoisomerase 1 using pHOT1 as substrate after 30 mins by agarose gel electrophoresis				Bioorg Med Chem 24: 6119-6130 (2016) Article DOI: 10.1016/j.bmc.2016.02.028 BindingDB Entry DOI: 10.7270/Q2BG2QZJ
					More data for this Ligand-Target Pair
DNA topoisomerase 1 (Homo sapiens (Human))	BDBM50203038 (CHEMBL3975075) Show SMILES [Br-].Cc1cc2cc[n+](Cc3ccccc3)c3-c4ccccc4-c(n1)c23 Show InChI InChI=1S/C22H17N2/c1-15-13-17-11-12-24(14-16-7-3-2-4-8-16)22-19-10-6-5-9-18(19)21(23-15)20(17)22/h2-13H,14H2,1H3/q+1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.08E+4	n/a	n/a	n/a	n/a	n/a	n/a
Southern Research Institute Curated by ChEMBL					Assay Description Inhibition of human DNA topoisomerase 1 using pHOT1 as substrate after 30 mins by agarose gel electrophoresis				Bioorg Med Chem 24: 6119-6130 (2016) Article DOI: 10.1016/j.bmc.2016.02.028 BindingDB Entry DOI: 10.7270/Q2BG2QZJ
					More data for this Ligand-Target Pair
DNA topoisomerase 1 (Homo sapiens (Human))	BDBM50203037 (CHEMBL3890769) Show SMILES [Br-].COc1cc(C[n+]2ccc3ccnc4-c5ccccc5-c2c34)cc(OC)c1 Show InChI InChI=1S/C23H19N2O2/c1-26-17-11-15(12-18(13-17)27-2)14-25-10-8-16-7-9-24-22-19-5-3-4-6-20(19)23(25)21(16)22/h3-13H,14H2,1-2H3/q+1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.44E+4	n/a	n/a	n/a	n/a	n/a	n/a
Southern Research Institute Curated by ChEMBL					Assay Description Inhibition of human DNA topoisomerase 1 using pHOT1 as substrate after 30 mins by agarose gel electrophoresis				Bioorg Med Chem 24: 6119-6130 (2016) Article DOI: 10.1016/j.bmc.2016.02.028 BindingDB Entry DOI: 10.7270/Q2BG2QZJ
					More data for this Ligand-Target Pair
DNA topoisomerase 1 (Homo sapiens (Human))	BDBM50203039 (CHEMBL3903152) Show SMILES Cc1cc(C)cc(CS([O-])(=O)=O)c1.N[n+]1ccc2ccnc3-c4ccccc4-c1c23 Show InChI InChI=1S/C14H10N3/c15-17-8-6-9-5-7-16-13-10-3-1-2-4-11(10)14(17)12(9)13/h1-8H,15H2/q+1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.57E+4	n/a	n/a	n/a	n/a	n/a	n/a
Southern Research Institute Curated by ChEMBL					Assay Description Inhibition of human DNA topoisomerase 1 using pHOT1 as substrate after 30 mins by agarose gel electrophoresis				Bioorg Med Chem 24: 6119-6130 (2016) Article DOI: 10.1016/j.bmc.2016.02.028 BindingDB Entry DOI: 10.7270/Q2BG2QZJ
					More data for this Ligand-Target Pair
DNA topoisomerase 1 (Homo sapiens (Human))	BDBM50203045 (CHEMBL3915026) Show SMILES [I-].CC[n+]1ccc2ccnc3-c4ccccc4-c1c23 Show InChI InChI=1S/C16H13N2/c1-2-18-10-8-11-7-9-17-15-12-5-3-4-6-13(12)16(18)14(11)15/h3-10H,2H2,1H3/q+1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.16E+4	n/a	n/a	n/a	n/a	n/a	n/a
Southern Research Institute Curated by ChEMBL					Assay Description Inhibition of human DNA topoisomerase 1 using pHOT1 as substrate after 30 mins by agarose gel electrophoresis				Bioorg Med Chem 24: 6119-6130 (2016) Article DOI: 10.1016/j.bmc.2016.02.028 BindingDB Entry DOI: 10.7270/Q2BG2QZJ
					More data for this Ligand-Target Pair
DNA topoisomerase 1 (Homo sapiens (Human))	BDBM50203047 (CHEMBL3932850) Show SMILES [Br-].Cc1ccc-2c(c1)-c1[n+](Cc3ccccc3)ccc3ccnc-2c13 Show InChI InChI=1S/C22H17N2/c1-15-7-8-18-19(13-15)22-20-17(9-11-23-21(18)20)10-12-24(22)14-16-5-3-2-4-6-16/h2-13H,14H2,1H3/q+1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.62E+4	n/a	n/a	n/a	n/a	n/a	n/a
Southern Research Institute Curated by ChEMBL					Assay Description Inhibition of human DNA topoisomerase 1 using pHOT1 as substrate after 30 mins by agarose gel electrophoresis				Bioorg Med Chem 24: 6119-6130 (2016) Article DOI: 10.1016/j.bmc.2016.02.028 BindingDB Entry DOI: 10.7270/Q2BG2QZJ
					More data for this Ligand-Target Pair
DNA topoisomerase 1 (Homo sapiens (Human))	BDBM50202834 (CHEMBL3957092) Show SMILES [Br-].Brc1cccc(C[n+]2ccc3ccnc4-c5ccccc5-c2c34)c1 Show InChI InChI=1S/C21H14BrN2/c22-16-5-3-4-14(12-16)13-24-11-9-15-8-10-23-20-17-6-1-2-7-18(17)21(24)19(15)20/h1-12H,13H2/q+1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.84E+4	n/a	n/a	n/a	n/a	n/a	n/a
Southern Research Institute Curated by ChEMBL					Assay Description Inhibition of human DNA topoisomerase 1 using pHOT1 as substrate after 30 mins by agarose gel electrophoresis				Bioorg Med Chem 24: 6119-6130 (2016) Article DOI: 10.1016/j.bmc.2016.02.028 BindingDB Entry DOI: 10.7270/Q2BG2QZJ
					More data for this Ligand-Target Pair
DNA topoisomerase 1 (Homo sapiens (Human))	BDBM50203050 (CHEMBL3984682) Show SMILES [Br-].[O-][N+](=O)c1ccc(C[n+]2ccc3ccnc4-c5ccccc5-c2c34)cc1 Show InChI InChI=1S/C21H14N3O2/c25-24(26)16-7-5-14(6-8-16)13-23-12-10-15-9-11-22-20-17-3-1-2-4-18(17)21(23)19(15)20/h1-12H,13H2/q+1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.99E+4	n/a	n/a	n/a	n/a	n/a	n/a
Southern Research Institute Curated by ChEMBL					Assay Description Inhibition of human DNA topoisomerase 1 using pHOT1 as substrate after 30 mins by agarose gel electrophoresis				Bioorg Med Chem 24: 6119-6130 (2016) Article DOI: 10.1016/j.bmc.2016.02.028 BindingDB Entry DOI: 10.7270/Q2BG2QZJ
					More data for this Ligand-Target Pair
DNA topoisomerase 1 (Homo sapiens (Human))	BDBM50202863 (CHEMBL3896944) Show SMILES [Br-].Clc1cccc(C[n+]2ccc3ccnc4-c5ccccc5-c2c34)c1 Show InChI InChI=1S/C21H14ClN2/c22-16-5-3-4-14(12-16)13-24-11-9-15-8-10-23-20-17-6-1-2-7-18(17)21(24)19(15)20/h1-12H,13H2/q+1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.36E+4	n/a	n/a	n/a	n/a	n/a	n/a
Southern Research Institute Curated by ChEMBL					Assay Description Inhibition of human DNA topoisomerase 1 using pHOT1 as substrate after 30 mins by agarose gel electrophoresis				Bioorg Med Chem 24: 6119-6130 (2016) Article DOI: 10.1016/j.bmc.2016.02.028 BindingDB Entry DOI: 10.7270/Q2BG2QZJ
					More data for this Ligand-Target Pair
DNA topoisomerase 1 (Homo sapiens (Human))	BDBM50202895 (CHEMBL3976611) Show SMILES [Br-].FC(F)(F)c1ccc(C[n+]2ccc3ccnc4-c5ccccc5-c2c34)cc1 Show InChI InChI=1S/C22H14F3N2/c23-22(24,25)16-7-5-14(6-8-16)13-27-12-10-15-9-11-26-20-17-3-1-2-4-18(17)21(27)19(15)20/h1-12H,13H2/q+1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.99E+4	n/a	n/a	n/a	n/a	n/a	n/a
Southern Research Institute Curated by ChEMBL					Assay Description Inhibition of human DNA topoisomerase 1 using pHOT1 as substrate after 30 mins by agarose gel electrophoresis				Bioorg Med Chem 24: 6119-6130 (2016) Article DOI: 10.1016/j.bmc.2016.02.028 BindingDB Entry DOI: 10.7270/Q2BG2QZJ
					More data for this Ligand-Target Pair
DNA topoisomerase 1 (Homo sapiens (Human))	BDBM50203066 (CHEMBL3904846) Show SMILES [Br-].C(c1ccc2ccccc2c1)[n+]1ccc2ccnc3-c4ccccc4-c1c23 Show InChI InChI=1S/C25H17N2/c1-2-6-20-15-17(9-10-18(20)5-1)16-27-14-12-19-11-13-26-24-21-7-3-4-8-22(21)25(27)23(19)24/h1-15H,16H2/q+1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	7.05E+4	n/a	n/a	n/a	n/a	n/a	n/a
Southern Research Institute Curated by ChEMBL					Assay Description Inhibition of human DNA topoisomerase 1 using pHOT1 as substrate after 30 mins by agarose gel electrophoresis				Bioorg Med Chem 24: 6119-6130 (2016) Article DOI: 10.1016/j.bmc.2016.02.028 BindingDB Entry DOI: 10.7270/Q2BG2QZJ
					More data for this Ligand-Target Pair
DNA topoisomerase 1 (Homo sapiens (Human))	BDBM50203112 (CHEMBL3984838) Show SMILES [Br-].C(c1ccccc1)[n+]1ccc2ccnc3-c4ccccc4-c1c23 Show InChI InChI=1S/C21H15N2/c1-2-6-15(7-3-1)14-23-13-11-16-10-12-22-20-17-8-4-5-9-18(17)21(23)19(16)20/h1-13H,14H2/q+1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.01E+5	n/a	n/a	n/a	n/a	n/a	n/a
Southern Research Institute Curated by ChEMBL					Assay Description Inhibition of human DNA topoisomerase 1 using pHOT1 as substrate after 30 mins by agarose gel electrophoresis				Bioorg Med Chem 24: 6119-6130 (2016) Article DOI: 10.1016/j.bmc.2016.02.028 BindingDB Entry DOI: 10.7270/Q2BG2QZJ
					More data for this Ligand-Target Pair
DNA topoisomerase 1 (Homo sapiens (Human))	BDBM50203051 (CHEMBL3985749) Show SMILES [Br-].Fc1ccc(C[n+]2ccc3ccnc4-c5ccccc5-c2c34)c(F)c1 Show InChI InChI=1S/C21H13F2N2/c22-15-6-5-14(18(23)11-15)12-25-10-8-13-7-9-24-20-16-3-1-2-4-17(16)21(25)19(13)20/h1-11H,12H2/q+1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.09E+5	n/a	n/a	n/a	n/a	n/a	n/a
Southern Research Institute Curated by ChEMBL					Assay Description Inhibition of human DNA topoisomerase 1 using pHOT1 as substrate after 30 mins by agarose gel electrophoresis				Bioorg Med Chem 24: 6119-6130 (2016) Article DOI: 10.1016/j.bmc.2016.02.028 BindingDB Entry DOI: 10.7270/Q2BG2QZJ
					More data for this Ligand-Target Pair
DNA topoisomerase 1 (Homo sapiens (Human))	BDBM50202839 (CHEMBL3968109) Show SMILES [Br-].Fc1ccc(C[n+]2ccc3ccnc4-c5ccccc5-c2c34)cc1 Show InChI InChI=1S/C21H14FN2/c22-16-7-5-14(6-8-16)13-24-12-10-15-9-11-23-20-17-3-1-2-4-18(17)21(24)19(15)20/h1-12H,13H2/q+1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.27E+5	n/a	n/a	n/a	n/a	n/a	n/a
Southern Research Institute Curated by ChEMBL					Assay Description Inhibition of human DNA topoisomerase 1 using pHOT1 as substrate after 30 mins by agarose gel electrophoresis				Bioorg Med Chem 24: 6119-6130 (2016) Article DOI: 10.1016/j.bmc.2016.02.028 BindingDB Entry DOI: 10.7270/Q2BG2QZJ
					More data for this Ligand-Target Pair
DNA topoisomerase 1 (Homo sapiens (Human))	BDBM50202836 (CHEMBL3894198) Show SMILES [Br-].O=C(C[n+]1ccc2ccnc3-c4ccccc4-c1c23)c1ccccc1 Show InChI InChI=1S/C22H15N2O/c25-19(15-6-2-1-3-7-15)14-24-13-11-16-10-12-23-21-17-8-4-5-9-18(17)22(24)20(16)21/h1-13H,14H2/q+1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.36E+5	n/a	n/a	n/a	n/a	n/a	n/a
Southern Research Institute Curated by ChEMBL					Assay Description Inhibition of human DNA topoisomerase 1 using pHOT1 as substrate after 30 mins by agarose gel electrophoresis				Bioorg Med Chem 24: 6119-6130 (2016) Article DOI: 10.1016/j.bmc.2016.02.028 BindingDB Entry DOI: 10.7270/Q2BG2QZJ
					More data for this Ligand-Target Pair
DNA topoisomerase 1 (Homo sapiens (Human))	BDBM50203067 (CHEMBL3922223) Show SMILES [Br-].CCOC(=O)C[n+]1ccc2ccnc3-c4ccccc4-c1c23 Show InChI InChI=1S/C18H15N2O2/c1-2-22-15(21)11-20-10-8-12-7-9-19-17-13-5-3-4-6-14(13)18(20)16(12)17/h3-10H,2,11H2,1H3/q+1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	2.42E+5	n/a	n/a	n/a	n/a	n/a	n/a
Southern Research Institute Curated by ChEMBL					Assay Description Inhibition of human DNA topoisomerase 1 using pHOT1 as substrate after 30 mins by agarose gel electrophoresis				Bioorg Med Chem 24: 6119-6130 (2016) Article DOI: 10.1016/j.bmc.2016.02.028 BindingDB Entry DOI: 10.7270/Q2BG2QZJ
					More data for this Ligand-Target Pair