BindingDB PrimarySearch

Found 78 hits with Last Name = 'emerling' and Initial = 'd'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Transient receptor potential cation channel subfamily V member 4 (Mus musculus)	BDBM50117636 (CHEMBL3613642) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	57	n/a	n/a	n/a	n/a	n/a	n/a
Renovis, Inc. Curated by ChEMBL					Assay Description Antagonist activity at mouse TRPV4 receptor expressed in HEK293 cells assessed as inhibition of 4alpha-PDD-stimulated calcium flux after 10 mins				Bioorg Med Chem Lett 25: 4011-5 (2015) Article DOI: 10.1016/j.bmcl.2015.06.098 BindingDB Entry DOI: 10.7270/Q2PG1THP
Renovis, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 [30-579] (Rattus norvegicus (rat))	BDBM50311785 (CHEMBL1079421 \| Phenmedipham) Show SMILES COC(=O)Nc1cccc(OC(=O)Nc2cccc(C)c2)c1 Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	77	n/a	n/a	n/a	n/a	n/a	n/a
Renovis, Inc Curated by ChEMBL					Assay Description Inhibition of rat FAAH				Bioorg Med Chem Lett 19: 6793-6 (2009) Article DOI: 10.1016/j.bmcl.2009.09.086 BindingDB Entry DOI: 10.7270/Q2BV7GRN
Renovis, Inc Curated by ChEMBL					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 4 (Rattus norvegicus)	BDBM50117636 (CHEMBL3613642) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	120	n/a	n/a	n/a	n/a	n/a	n/a
Renovis, Inc. Curated by ChEMBL					Assay Description Antagonist activity at rat TRPV4 receptor expressed in HEK293 cells assessed as inhibition of 4alpha-PDD-stimulated calcium flux after 10 mins				Bioorg Med Chem Lett 25: 4011-5 (2015) Article DOI: 10.1016/j.bmcl.2015.06.098 BindingDB Entry DOI: 10.7270/Q2PG1THP
Renovis, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 (Homo sapiens (Human))	BDBM50311785 (CHEMBL1079421 \| Phenmedipham) Show SMILES COC(=O)Nc1cccc(OC(=O)Nc2cccc(C)c2)c1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	152	n/a	n/a	n/a	n/a	n/a	n/a
Renovis, Inc Curated by ChEMBL					Assay Description Inhibition of human FAAH-mediated hydrolysis of [3H]AEA				Bioorg Med Chem Lett 19: 6793-6 (2009) Article DOI: 10.1016/j.bmcl.2009.09.086 BindingDB Entry DOI: 10.7270/Q2BV7GRN
Renovis, Inc Curated by ChEMBL					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily M member 8 (Homo sapiens (Human))	BDBM50331290 (CHEMBL1289953 \| N-(3-aminopropyl)-2-(3-methylbenzy...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	160	n/a	n/a	n/a	n/a	n/a	n/a
Renovis, Inc. Curated by ChEMBL					Assay Description Antagonist activity at human TRPM8 receptor expressed in human T-REx-293 cells assessed as inhibition of menthol-induced 45calcium influx treated 5 m...				Bioorg Med Chem Lett 20: 7076-9 (2010) Article DOI: 10.1016/j.bmcl.2010.09.099 BindingDB Entry DOI: 10.7270/Q2DN459H
Renovis, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily M member 8 (Homo sapiens (Human))	BDBM50331290 (CHEMBL1289953 \| N-(3-aminopropyl)-2-(3-methylbenzy...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	190	n/a	n/a	n/a	n/a	n/a	n/a
Renovis, Inc. Curated by ChEMBL					Assay Description Antagonist activity at human TRPM8 receptor expressed in human T-REx-293 cells assessed as inhibition of icilin-induced 45calcium influx treated 5 mi...				Bioorg Med Chem Lett 20: 7076-9 (2010) Article DOI: 10.1016/j.bmcl.2010.09.099 BindingDB Entry DOI: 10.7270/Q2DN459H
Renovis, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 4 (Homo sapiens (Human))	BDBM50117640 (CHEMBL3613639) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	260	n/a	n/a	n/a	n/a	n/a	n/a
Renovis, Inc. Curated by ChEMBL					Assay Description Antagonist activity at human TRPV4 receptor expressed in HEK293 cells assessed as inhibition of EC80 of 4alpha-PDD-stimulated calcium flux after 10 m...				Bioorg Med Chem Lett 25: 4011-5 (2015) Article DOI: 10.1016/j.bmcl.2015.06.098 BindingDB Entry DOI: 10.7270/Q2PG1THP
Renovis, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 4 (Mus musculus)	BDBM50117636 (CHEMBL3613642) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	320	n/a	n/a	n/a	n/a	n/a	n/a
Renovis, Inc. Curated by ChEMBL					Assay Description Antagonist activity at mouse TRPV4 receptor expressed in HEK293 cells assessed as inhibition of EC80 of 4alpha-PDD-stimulated calcium flux after 10 m...				Bioorg Med Chem Lett 25: 4011-5 (2015) Article DOI: 10.1016/j.bmcl.2015.06.098 BindingDB Entry DOI: 10.7270/Q2PG1THP
Renovis, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily M member 8 (Homo sapiens (Human))	BDBM82302 (5-BENZYLOXYTRYPTAMINE \| 5-BZT \| CAS_20776-45-8 \| C...) Show SMILES NCCc1c[nH]c2ccc(OCc3ccccc3)cc12 Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	340	n/a	n/a	n/a	n/a	n/a	n/a
Renovis, Inc. Curated by ChEMBL					Assay Description Antagonist activity at human TRPM8 receptor expressed in human T-REx-293 cells assessed as inhibition of menthol-induced 45calcium influx treated 5 m...				Bioorg Med Chem Lett 20: 7076-9 (2010) Article DOI: 10.1016/j.bmcl.2010.09.099 BindingDB Entry DOI: 10.7270/Q2DN459H
Renovis, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 4 (Rattus norvegicus)	BDBM50117639 (CHEMBL3613640) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	370	n/a	n/a	n/a	n/a	n/a	n/a
Renovis, Inc. Curated by ChEMBL					Assay Description Antagonist activity at rat TRPV4 receptor expressed in HEK293 cells assessed as inhibition of EC80 of 4alpha-PDD-stimulated calcium flux after 10 min...				Bioorg Med Chem Lett 25: 4011-5 (2015) Article DOI: 10.1016/j.bmcl.2015.06.098 BindingDB Entry DOI: 10.7270/Q2PG1THP
Renovis, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 (Homo sapiens (Human))	BDBM50311785 (CHEMBL1079421 \| Phenmedipham) Show SMILES COC(=O)Nc1cccc(OC(=O)Nc2cccc(C)c2)c1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	377	n/a	n/a	n/a	n/a	n/a	n/a
Renovis, Inc Curated by ChEMBL					Assay Description Inhibition of human FAAH				Bioorg Med Chem Lett 19: 6793-6 (2009) Article DOI: 10.1016/j.bmcl.2009.09.086 BindingDB Entry DOI: 10.7270/Q2BV7GRN
Renovis, Inc Curated by ChEMBL					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 4 (Homo sapiens (Human))	BDBM50117639 (CHEMBL3613640) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	380	n/a	n/a	n/a	n/a	n/a	n/a
Renovis, Inc. Curated by ChEMBL					Assay Description Antagonist activity at human TRPV4 receptor expressed in HEK293 cells assessed as inhibition of EC80 of 4alpha-PDD-stimulated calcium flux after 10 m...				Bioorg Med Chem Lett 25: 4011-5 (2015) Article DOI: 10.1016/j.bmcl.2015.06.098 BindingDB Entry DOI: 10.7270/Q2PG1THP
Renovis, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 4 (Homo sapiens (Human))	BDBM50117646 (CHEMBL3613628) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	390	n/a	n/a	n/a	n/a	n/a	n/a
Renovis, Inc. Curated by ChEMBL					Assay Description Antagonist activity at human TRPV4 receptor expressed in HEK293 cells assessed as inhibition of EC80 of 4alpha-PDD-stimulated calcium flux after 10 m...				Bioorg Med Chem Lett 25: 4011-5 (2015) Article DOI: 10.1016/j.bmcl.2015.06.098 BindingDB Entry DOI: 10.7270/Q2PG1THP
Renovis, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 4 (Rattus norvegicus)	BDBM50117640 (CHEMBL3613639) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	390	n/a	n/a	n/a	n/a	n/a	n/a
Renovis, Inc. Curated by ChEMBL					Assay Description Antagonist activity at rat TRPV4 receptor expressed in HEK293 cells assessed as inhibition of EC80 of 4alpha-PDD-stimulated calcium flux after 10 min...				Bioorg Med Chem Lett 25: 4011-5 (2015) Article DOI: 10.1016/j.bmcl.2015.06.098 BindingDB Entry DOI: 10.7270/Q2PG1THP
Renovis, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 4 (Homo sapiens (Human))	BDBM50117636 (CHEMBL3613642) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	420	n/a	n/a	n/a	n/a	n/a	n/a
Renovis, Inc. Curated by ChEMBL					Assay Description Antagonist activity at human TRPV4 receptor expressed in HEK293 cells assessed as inhibition of EC80 of 4alpha-PDD-stimulated calcium flux after 10 m...				Bioorg Med Chem Lett 25: 4011-5 (2015) Article DOI: 10.1016/j.bmcl.2015.06.098 BindingDB Entry DOI: 10.7270/Q2PG1THP
Renovis, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 (Homo sapiens (Human))	BDBM50311786 (Amperozide \| CHEMBL1079935) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	455	n/a	n/a	n/a	n/a	n/a	n/a
Renovis, Inc Curated by ChEMBL					Assay Description Inhibition of human FAAH-mediated hydrolysis of [3H]AEA				Bioorg Med Chem Lett 19: 6793-6 (2009) Article DOI: 10.1016/j.bmcl.2009.09.086 BindingDB Entry DOI: 10.7270/Q2BV7GRN
Renovis, Inc Curated by ChEMBL					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 4 (Rattus norvegicus)	BDBM50117638 (CHEMBL3613641) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	490	n/a	n/a	n/a	n/a	n/a	n/a
Renovis, Inc. Curated by ChEMBL					Assay Description Antagonist activity at rat TRPV4 receptor expressed in HEK293 cells assessed as inhibition of EC80 of 4alpha-PDD-stimulated calcium flux after 10 min...				Bioorg Med Chem Lett 25: 4011-5 (2015) Article DOI: 10.1016/j.bmcl.2015.06.098 BindingDB Entry DOI: 10.7270/Q2PG1THP
Renovis, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 4 (Homo sapiens (Human))	BDBM50117638 (CHEMBL3613641) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	540	n/a	n/a	n/a	n/a	n/a	n/a
Renovis, Inc. Curated by ChEMBL					Assay Description Antagonist activity at human TRPV4 receptor expressed in HEK293 cells assessed as inhibition of EC80 of 4alpha-PDD-stimulated calcium flux after 10 m...				Bioorg Med Chem Lett 25: 4011-5 (2015) Article DOI: 10.1016/j.bmcl.2015.06.098 BindingDB Entry DOI: 10.7270/Q2PG1THP
Renovis, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 4 (Homo sapiens (Human))	BDBM50117636 (CHEMBL3613642) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	570	n/a	n/a	n/a	n/a	n/a	n/a
Renovis, Inc. Curated by ChEMBL					Assay Description Antagonist activity at human TRPV4 expressed in HEK293 cells assessed as inhibition of 20% hypotonic solution-induced Ca2+ influx				Bioorg Med Chem Lett 25: 4011-5 (2015) Article DOI: 10.1016/j.bmcl.2015.06.098 BindingDB Entry DOI: 10.7270/Q2PG1THP
Renovis, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 4 (Rattus norvegicus)	BDBM50117636 (CHEMBL3613642) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	660	n/a	n/a	n/a	n/a	n/a	n/a
Renovis, Inc. Curated by ChEMBL					Assay Description Antagonist activity at rat TRPV4 receptor expressed in HEK293 cells assessed as inhibition of EC80 of 4alpha-PDD-stimulated calcium flux after 10 min...				Bioorg Med Chem Lett 25: 4011-5 (2015) Article DOI: 10.1016/j.bmcl.2015.06.098 BindingDB Entry DOI: 10.7270/Q2PG1THP
Renovis, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily M member 8 (Homo sapiens (Human))	BDBM82302 (5-BENZYLOXYTRYPTAMINE \| 5-BZT \| CAS_20776-45-8 \| C...) Show SMILES NCCc1c[nH]c2ccc(OCc3ccccc3)cc12 Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	660	n/a	n/a	n/a	n/a	n/a	n/a
Renovis, Inc. Curated by ChEMBL					Assay Description Antagonist activity at human TRPM8 receptor expressed in human T-REx-293 cells assessed as inhibition of icilin-induced 45calcium influx treated 5 mi...				Bioorg Med Chem Lett 20: 7076-9 (2010) Article DOI: 10.1016/j.bmcl.2010.09.099 BindingDB Entry DOI: 10.7270/Q2DN459H
Renovis, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 4 (Homo sapiens (Human))	BDBM50117645 (CHEMBL3613629) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	710	n/a	n/a	n/a	n/a	n/a	n/a
Renovis, Inc. Curated by ChEMBL					Assay Description Antagonist activity at human TRPV4 receptor expressed in HEK293 cells assessed as inhibition of EC80 of 4alpha-PDD-stimulated calcium flux after 10 m...				Bioorg Med Chem Lett 25: 4011-5 (2015) Article DOI: 10.1016/j.bmcl.2015.06.098 BindingDB Entry DOI: 10.7270/Q2PG1THP
Renovis, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 4 (Homo sapiens (Human))	BDBM50117650 (CHEMBL3613638) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	800	n/a	n/a	n/a	n/a	n/a	n/a
Renovis, Inc. Curated by ChEMBL					Assay Description Antagonist activity at human TRPV4 receptor expressed in HEK293 cells assessed as inhibition of EC80 of 4alpha-PDD-stimulated calcium flux after 10 m...				Bioorg Med Chem Lett 25: 4011-5 (2015) Article DOI: 10.1016/j.bmcl.2015.06.098 BindingDB Entry DOI: 10.7270/Q2PG1THP
Renovis, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 4 (Homo sapiens (Human))	BDBM50117652 (CHEMBL3613636) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	910	n/a	n/a	n/a	n/a	n/a	n/a
Renovis, Inc. Curated by ChEMBL					Assay Description Antagonist activity at human TRPV4 receptor expressed in HEK293 cells assessed as inhibition of EC80 of 4alpha-PDD-stimulated calcium flux after 10 m...				Bioorg Med Chem Lett 25: 4011-5 (2015) Article DOI: 10.1016/j.bmcl.2015.06.098 BindingDB Entry DOI: 10.7270/Q2PG1THP
Renovis, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 4 (Homo sapiens (Human))	BDBM50117637 (CHEMBL3613643) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	930	n/a	n/a	n/a	n/a	n/a	n/a
Renovis, Inc. Curated by ChEMBL					Assay Description Antagonist activity at human TRPV4 receptor expressed in HEK293 cells assessed as inhibition of EC80 of 4alpha-PDD-stimulated calcium flux after 10 m...				Bioorg Med Chem Lett 25: 4011-5 (2015) Article DOI: 10.1016/j.bmcl.2015.06.098 BindingDB Entry DOI: 10.7270/Q2PG1THP
Renovis, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 4 (Homo sapiens (Human))	BDBM50117647 (CHEMBL3613627) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	930	n/a	n/a	n/a	n/a	n/a	n/a
Renovis, Inc. Curated by ChEMBL					Assay Description Antagonist activity at human TRPV4 receptor expressed in HEK293 cells assessed as inhibition of EC80 of 4alpha-PDD-stimulated calcium flux after 10 m...				Bioorg Med Chem Lett 25: 4011-5 (2015) Article DOI: 10.1016/j.bmcl.2015.06.098 BindingDB Entry DOI: 10.7270/Q2PG1THP
Renovis, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 4 (Rattus norvegicus)	BDBM50117645 (CHEMBL3613629) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	940	n/a	n/a	n/a	n/a	n/a	n/a
Renovis, Inc. Curated by ChEMBL					Assay Description Antagonist activity at rat TRPV4 receptor expressed in HEK293 cells assessed as inhibition of EC80 of 4alpha-PDD-stimulated calcium flux after 10 min...				Bioorg Med Chem Lett 25: 4011-5 (2015) Article DOI: 10.1016/j.bmcl.2015.06.098 BindingDB Entry DOI: 10.7270/Q2PG1THP
Renovis, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 4 (Rattus norvegicus)	BDBM50117646 (CHEMBL3613628) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.05E+3	n/a	n/a	n/a	n/a	n/a	n/a
Renovis, Inc. Curated by ChEMBL					Assay Description Antagonist activity at rat TRPV4 receptor expressed in HEK293 cells assessed as inhibition of EC80 of 4alpha-PDD-stimulated calcium flux after 10 min...				Bioorg Med Chem Lett 25: 4011-5 (2015) Article DOI: 10.1016/j.bmcl.2015.06.098 BindingDB Entry DOI: 10.7270/Q2PG1THP
Renovis, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 4 (Homo sapiens (Human))	BDBM50117651 (CHEMBL3613637) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.28E+3	n/a	n/a	n/a	n/a	n/a	n/a
Renovis, Inc. Curated by ChEMBL					Assay Description Antagonist activity at human TRPV4 receptor expressed in HEK293 cells assessed as inhibition of EC80 of 4alpha-PDD-stimulated calcium flux after 10 m...				Bioorg Med Chem Lett 25: 4011-5 (2015) Article DOI: 10.1016/j.bmcl.2015.06.098 BindingDB Entry DOI: 10.7270/Q2PG1THP
Renovis, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 4 (Homo sapiens (Human))	BDBM50117654 (CHEMBL3613634) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	1.32E+3	n/a	n/a	n/a	n/a	n/a	n/a
Renovis, Inc. Curated by ChEMBL					Assay Description Antagonist activity at human TRPV4 receptor expressed in HEK293 cells assessed as inhibition of EC80 of 4alpha-PDD-stimulated calcium flux after 10 m...				Bioorg Med Chem Lett 25: 4011-5 (2015) Article DOI: 10.1016/j.bmcl.2015.06.098 BindingDB Entry DOI: 10.7270/Q2PG1THP
Renovis, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 (Homo sapiens (Human))	BDBM50311786 (Amperozide \| CHEMBL1079935) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	1.34E+3	n/a	n/a	n/a	n/a	n/a	n/a
Renovis, Inc Curated by ChEMBL					Assay Description Inhibition of human FAAH				Bioorg Med Chem Lett 19: 6793-6 (2009) Article DOI: 10.1016/j.bmcl.2009.09.086 BindingDB Entry DOI: 10.7270/Q2BV7GRN
Renovis, Inc Curated by ChEMBL					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily M member 8 (Homo sapiens (Human))	BDBM50331285 (2-(5-(benzyloxy)-2-methyl-1H-indol-3-yl)ethanamine...) Show SMILES Cc1[nH]c2ccc(OCc3ccccc3)cc2c1CCN Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Renovis, Inc. Curated by ChEMBL					Assay Description Antagonist activity at human TRPM8 receptor expressed in human T-REx-293 cells assessed as inhibition of menthol-induced 45calcium influx treated 5 m...				Bioorg Med Chem Lett 20: 7076-9 (2010) Article DOI: 10.1016/j.bmcl.2010.09.099 BindingDB Entry DOI: 10.7270/Q2DN459H
Renovis, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 4 (Rattus norvegicus)	BDBM50117644 (CHEMBL3613630) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.94E+3	n/a	n/a	n/a	n/a	n/a	n/a
Renovis, Inc. Curated by ChEMBL					Assay Description Antagonist activity at rat TRPV4 receptor expressed in HEK293 cells assessed as inhibition of EC80 of 4alpha-PDD-stimulated calcium flux after 10 min...				Bioorg Med Chem Lett 25: 4011-5 (2015) Article DOI: 10.1016/j.bmcl.2015.06.098 BindingDB Entry DOI: 10.7270/Q2PG1THP
Renovis, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 4 (Rattus norvegicus)	BDBM50117636 (CHEMBL3613642) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Renovis, Inc. Curated by ChEMBL					Assay Description Antagonist activity at rat TRPV4 expressed in HEK293 cells assessed as inhibition of 20% hypotonic solution-induced Ca2+ influx				Bioorg Med Chem Lett 25: 4011-5 (2015) Article DOI: 10.1016/j.bmcl.2015.06.098 BindingDB Entry DOI: 10.7270/Q2PG1THP
Renovis, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 4 (Homo sapiens (Human))	BDBM50117653 (CHEMBL3613635) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.11E+3	n/a	n/a	n/a	n/a	n/a	n/a
Renovis, Inc. Curated by ChEMBL					Assay Description Antagonist activity at human TRPV4 receptor expressed in HEK293 cells assessed as inhibition of EC80 of 4alpha-PDD-stimulated calcium flux after 10 m...				Bioorg Med Chem Lett 25: 4011-5 (2015) Article DOI: 10.1016/j.bmcl.2015.06.098 BindingDB Entry DOI: 10.7270/Q2PG1THP
Renovis, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 4 (Homo sapiens (Human))	BDBM50117644 (CHEMBL3613630) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.17E+3	n/a	n/a	n/a	n/a	n/a	n/a
Renovis, Inc. Curated by ChEMBL					Assay Description Antagonist activity at human TRPV4 receptor expressed in HEK293 cells assessed as inhibition of EC80 of 4alpha-PDD-stimulated calcium flux after 10 m...				Bioorg Med Chem Lett 25: 4011-5 (2015) Article DOI: 10.1016/j.bmcl.2015.06.098 BindingDB Entry DOI: 10.7270/Q2PG1THP
Renovis, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily M member 8 (Homo sapiens (Human))	BDBM50331285 (2-(5-(benzyloxy)-2-methyl-1H-indol-3-yl)ethanamine...) Show SMILES Cc1[nH]c2ccc(OCc3ccccc3)cc2c1CCN Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.36E+3	n/a	n/a	n/a	n/a	n/a	n/a
Renovis, Inc. Curated by ChEMBL					Assay Description Antagonist activity at human TRPM8 receptor expressed in human T-REx-293 cells assessed as inhibition of icilin-induced 45calcium influx treated 5 mi...				Bioorg Med Chem Lett 20: 7076-9 (2010) Article DOI: 10.1016/j.bmcl.2010.09.099 BindingDB Entry DOI: 10.7270/Q2DN459H
Renovis, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily A member 1 (Homo sapiens (Human))	BDBM50305208 (3-Methyl-4-phenylbut-3-en-2-one oxime \| CHEMBL6037...) Show SMILES CC(N=O)C(C)=Cc1ccccc1 \|w:6.6\| Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
Renovis, Inc. Curated by ChEMBL					Assay Description Antagonist activity at human TRPA1 expressed in HEK293 cells assessed as [45]Ca2+ influx by microbeta plate count				Bioorg Med Chem Lett 20: 276-9 (2010) Article DOI: 10.1016/j.bmcl.2009.10.113 BindingDB Entry DOI: 10.7270/Q2K074C4
Renovis, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily A member 1 (Homo sapiens (Human))	BDBM50305207 (4-(4-chlorophenyl)-3-methylbut-3-en-2-one oxime \| ...) Show SMILES CC(N=O)C(C)=Cc1ccc(Cl)cc1 \|w:6.6\| Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
Renovis, Inc. Curated by ChEMBL					Assay Description Antagonist activity at human TRPA1 expressed in HEK293 cells assessed as [45]Ca2+ influx by microbeta plate count				Bioorg Med Chem Lett 20: 276-9 (2010) Article DOI: 10.1016/j.bmcl.2009.10.113 BindingDB Entry DOI: 10.7270/Q2K074C4
Renovis, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 4 (Rattus norvegicus)	BDBM50117637 (CHEMBL3613643) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.92E+3	n/a	n/a	n/a	n/a	n/a	n/a
Renovis, Inc. Curated by ChEMBL					Assay Description Antagonist activity at rat TRPV4 receptor expressed in HEK293 cells assessed as inhibition of EC80 of 4alpha-PDD-stimulated calcium flux after 10 min...				Bioorg Med Chem Lett 25: 4011-5 (2015) Article DOI: 10.1016/j.bmcl.2015.06.098 BindingDB Entry DOI: 10.7270/Q2PG1THP
Renovis, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily M member 8 (Homo sapiens (Human))	BDBM50247069 (2-(7-(benzyloxy)-1H-indol-3-yl)ethanamine \| CHEMBL...) Show SMILES NCCc1c[nH]c2c(OCc3ccccc3)cccc12 Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	3.34E+3	n/a	n/a	n/a	n/a	n/a	n/a
Renovis, Inc. Curated by ChEMBL					Assay Description Antagonist activity at human TRPM8 receptor expressed in human T-REx-293 cells assessed as inhibition of menthol-induced 45calcium influx treated 5 m...				Bioorg Med Chem Lett 20: 7076-9 (2010) Article DOI: 10.1016/j.bmcl.2010.09.099 BindingDB Entry DOI: 10.7270/Q2DN459H
Renovis, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 4 (Rattus norvegicus)	BDBM50117647 (CHEMBL3613627) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
Renovis, Inc. Curated by ChEMBL					Assay Description Antagonist activity at rat TRPV4 receptor expressed in HEK293 cells assessed as inhibition of EC80 of 4alpha-PDD-stimulated calcium flux after 10 min...				Bioorg Med Chem Lett 25: 4011-5 (2015) Article DOI: 10.1016/j.bmcl.2015.06.098 BindingDB Entry DOI: 10.7270/Q2PG1THP
Renovis, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 4 (Homo sapiens (Human))	BDBM50117641 (CHEMBL3613633) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.22E+3	n/a	n/a	n/a	n/a	n/a	n/a
Renovis, Inc. Curated by ChEMBL					Assay Description Antagonist activity at human TRPV4 receptor expressed in HEK293 cells assessed as inhibition of EC80 of 4alpha-PDD-stimulated calcium flux after 10 m...				Bioorg Med Chem Lett 25: 4011-5 (2015) Article DOI: 10.1016/j.bmcl.2015.06.098 BindingDB Entry DOI: 10.7270/Q2PG1THP
Renovis, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 4 (Rattus norvegicus)	BDBM50117649 (CHEMBL3613625) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
Renovis, Inc. Curated by ChEMBL					Assay Description Antagonist activity at rat TRPV4 receptor expressed in HEK293 cells assessed as inhibition of EC80 of 4alpha-PDD-stimulated calcium flux after 10 min...				Bioorg Med Chem Lett 25: 4011-5 (2015) Article DOI: 10.1016/j.bmcl.2015.06.098 BindingDB Entry DOI: 10.7270/Q2PG1THP
Renovis, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 4 (Homo sapiens (Human))	BDBM50117648 (CHEMBL3613626) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.93E+3	n/a	n/a	n/a	n/a	n/a	n/a
Renovis, Inc. Curated by ChEMBL					Assay Description Antagonist activity at human TRPV4 receptor expressed in HEK293 cells assessed as inhibition of EC80 of 4alpha-PDD-stimulated calcium flux after 10 m...				Bioorg Med Chem Lett 25: 4011-5 (2015) Article DOI: 10.1016/j.bmcl.2015.06.098 BindingDB Entry DOI: 10.7270/Q2PG1THP
Renovis, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily M member 8 (Homo sapiens (Human))	BDBM50054758 (CHEMBL357130 \| [2-(5-Benzyloxy-1H-indol-3-yl)-ethy...) Show SMILES CN(C)CCc1c[nH]c2ccc(OCc3ccccc3)cc12 Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.63E+3	n/a	n/a	n/a	n/a	n/a	n/a
Renovis, Inc. Curated by ChEMBL					Assay Description Antagonist activity at human TRPM8 receptor expressed in human T-REx-293 cells assessed as inhibition of menthol-induced 45calcium influx treated 5 m...				Bioorg Med Chem Lett 20: 7076-9 (2010) Article DOI: 10.1016/j.bmcl.2010.09.099 BindingDB Entry DOI: 10.7270/Q2DN459H
Renovis, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 4 (Rattus norvegicus)	BDBM50117641 (CHEMBL3613633) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.74E+3	n/a	n/a	n/a	n/a	n/a	n/a
Renovis, Inc. Curated by ChEMBL					Assay Description Antagonist activity at rat TRPV4 receptor expressed in HEK293 cells assessed as inhibition of EC80 of 4alpha-PDD-stimulated calcium flux after 10 min...				Bioorg Med Chem Lett 25: 4011-5 (2015) Article DOI: 10.1016/j.bmcl.2015.06.098 BindingDB Entry DOI: 10.7270/Q2PG1THP
Renovis, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily M member 8 (Homo sapiens (Human))	BDBM50054758 (CHEMBL357130 \| [2-(5-Benzyloxy-1H-indol-3-yl)-ethy...) Show SMILES CN(C)CCc1c[nH]c2ccc(OCc3ccccc3)cc12 Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.96E+3	n/a	n/a	n/a	n/a	n/a	n/a
Renovis, Inc. Curated by ChEMBL					Assay Description Antagonist activity at human TRPM8 receptor expressed in human T-REx-293 cells assessed as inhibition of icilin-induced 45calcium influx treated 5 mi...				Bioorg Med Chem Lett 20: 7076-9 (2010) Article DOI: 10.1016/j.bmcl.2010.09.099 BindingDB Entry DOI: 10.7270/Q2DN459H
Renovis, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 4 (Rattus norvegicus)	BDBM50117648 (CHEMBL3613626) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	6.49E+3	n/a	n/a	n/a	n/a	n/a	n/a
Renovis, Inc. Curated by ChEMBL					Assay Description Antagonist activity at rat TRPV4 receptor expressed in HEK293 cells assessed as inhibition of EC80 of 4alpha-PDD-stimulated calcium flux after 10 min...				Bioorg Med Chem Lett 25: 4011-5 (2015) Article DOI: 10.1016/j.bmcl.2015.06.098 BindingDB Entry DOI: 10.7270/Q2PG1THP
Renovis, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 4 (Homo sapiens (Human))	BDBM50117649 (CHEMBL3613625) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.53E+3	n/a	n/a	n/a	n/a	n/a	n/a
Renovis, Inc. Curated by ChEMBL					Assay Description Antagonist activity at human TRPV4 receptor expressed in HEK293 cells assessed as inhibition of EC80 of 4alpha-PDD-stimulated calcium flux after 10 m...				Bioorg Med Chem Lett 25: 4011-5 (2015) Article DOI: 10.1016/j.bmcl.2015.06.098 BindingDB Entry DOI: 10.7270/Q2PG1THP
Renovis, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair

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