Compile Data Set for Download or QSAR

Found 209 hits with Last Name = 'brooks' and Initial = 'dw'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus)	BDBM50015087 (2',4',6'-Trimethyl-biphenyl-4-carboxylic acid hydr...) Show SMILES CN(O)C(=O)c1ccc(cc1)-c1c(C)cc(C)cc1C Show InChI InChI=1S/C17H19NO2/c1-11-9-12(2)16(13(3)10-11)14-5-7-15(8-6-14)17(19)18(4)20/h5-10,20H,1-4H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	60	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description In vitro inhibitory activity against 5-lipoxygenase in rat RBL-1 cells				J Med Chem 30: 2121-6 (1987) BindingDB Entry DOI: 10.7270/Q29Z93XT
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid lipoxygenase ALOX12 (Homo sapiens (Human))	BDBM50009004 ((phenidone)1-Phenyl-pyrazolidin-3-one | 1-Phenyl-p...) Show SMILES O=C1CCN(N1)c1ccccc1 Show InChI InChI=1S/C9H10N2O/c12-9-6-7-11(10-9)8-4-2-1-3-5-8/h1-5H,6-7H2,(H,10,12)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibitory activity of the compound against human platelet 12-lipoxygenase was evaluated				Bioorg Med Chem Lett 2: 1353-1356 (1992) Article DOI: 10.1016/S0960-894X(00)80511-9 BindingDB Entry DOI: 10.7270/Q2H41RC2
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus)	BDBM50015178 ((E)-N-hydroxy-N-methyl-3-(naphthalen-2-yl)acrylami...) Show SMILES CN(O)C(=O)\C=C\c1ccc2ccccc2c1 Show InChI InChI=1S/C14H13NO2/c1-15(17)14(16)9-7-11-6-8-12-4-2-3-5-13(12)10-11/h2-10,17H,1H3/b9-7+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description In vitro inhibitory activity against 5-lipoxygenase in rat RBL-1 cells				J Med Chem 30: 2121-6 (1987) BindingDB Entry DOI: 10.7270/Q29Z93XT
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus)	BDBM50024448 (5-Hydroxycarbamoylmethyl-icosa-6,8,11,14-tetraenoi...) Show SMILES CCCCC\C=C/C\C=C/C\C=C/C=C/C(CCCC(O)=O)CC(=O)NO Show InChI InChI=1S/C22H35NO4/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-16-20(19-21(24)23-27)17-15-18-22(25)26/h6-7,9-10,12-14,16,20,27H,2-5,8,11,15,17-19H2,1H3,(H,23,24)(H,25,26)/b7-6-,10-9-,13-12-,16-14+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	190	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro inhibitory activity against 5-lipoxygenase from rat basophilic leukemia cells.				J Med Chem 30: 1177-86 (1987) BindingDB Entry DOI: 10.7270/Q25M668Q
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus)	BDBM50015163 (CHEMBL65655 | N-Hydroxy-N-methyl-3-(2',4',6'-trime...) Show SMILES CN(O)C(=O)\C=C\c1ccc(cc1)-c1c(C)cc(C)cc1C Show InChI InChI=1S/C19H21NO2/c1-13-11-14(2)19(15(3)12-13)17-8-5-16(6-9-17)7-10-18(21)20(4)22/h5-12,22H,1-4H3/b10-7+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	220	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description In vitro inhibitory activity against 5-lipoxygenase in rat RBL-1 cells				J Med Chem 30: 2121-6 (1987) BindingDB Entry DOI: 10.7270/Q29Z93XT
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus)	BDBM50015159 (2-(4-Benzyloxy-phenyl)-N-hydroxy-N-methyl-propiona...) Show SMILES CC(C(=O)N(C)O)c1ccc(OCc2ccccc2)cc1 Show InChI InChI=1S/C17H19NO3/c1-13(17(19)18(2)20)15-8-10-16(11-9-15)21-12-14-6-4-3-5-7-14/h3-11,13,20H,12H2,1-2H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	280	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description In vitro inhibitory activity against 5-lipoxygenase in rat RBL-1 cells				J Med Chem 30: 2121-6 (1987) BindingDB Entry DOI: 10.7270/Q29Z93XT
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus)	BDBM50015159 (2-(4-Benzyloxy-phenyl)-N-hydroxy-N-methyl-propiona...) Show SMILES CC(C(=O)N(C)O)c1ccc(OCc2ccccc2)cc1 Show InChI InChI=1S/C17H19NO3/c1-13(17(19)18(2)20)15-8-10-16(11-9-15)21-12-14-6-4-3-5-7-14/h3-11,13,20H,12H2,1-2H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	280	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description In vitro inhibition of 5-lipoxygenase in RBL-1 cells				J Med Chem 31: 3-5 (1988) BindingDB Entry DOI: 10.7270/Q2V40T6C
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus)	BDBM50015174 (2',4',6'-Trimethyl-biphenyl-4-carboxylic acid hydr...) Show SMILES Cc1cc(C)c(c(C)c1)-c1ccc(cc1)C(=O)NO Show InChI InChI=1S/C16H17NO2/c1-10-8-11(2)15(12(3)9-10)13-4-6-14(7-5-13)16(18)17-19/h4-9,19H,1-3H3,(H,17,18)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	290	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description In vitro inhibitory activity against 5-lipoxygenase in rat RBL-1 cells				J Med Chem 30: 2121-6 (1987) BindingDB Entry DOI: 10.7270/Q29Z93XT
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus)	BDBM50012887 (CHEMBL65430 | N-Hydroxy-2-(4-isobutyl-phenyl)-N-me...) Show SMILES CC(C)Cc1ccc(cc1)C(C)C(=O)N(C)O Show InChI InChI=1S/C14H21NO2/c1-10(2)9-12-5-7-13(8-6-12)11(3)14(16)15(4)17/h5-8,10-11,17H,9H2,1-4H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	290	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description In vitro inhibition of 5-lipoxygenase in RBL-1 cells				J Med Chem 31: 3-5 (1988) BindingDB Entry DOI: 10.7270/Q2V40T6C
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus)	BDBM7460 (2-(3,4-dihydroxyphenyl)-3,5,7-trihydroxy-4H-chrome...) Show SMILES Oc1cc(O)c2c(c1)oc(-c1ccc(O)c(O)c1)c(O)c2=O Show InChI InChI=1S/C15H10O7/c16-7-4-10(19)12-11(5-7)22-15(14(21)13(12)20)6-1-2-8(17)9(18)3-6/h1-5,16-19,21H	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PubMed	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description In vitro inhibition of 5-lipoxygenase (5-lo) from the 20000 g supernatant of RBI-1 cells				J Med Chem 34: 2158-65 (1991) BindingDB Entry DOI: 10.7270/Q2NS0SWM
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Homo sapiens (Human))	BDBM50009004 ((phenidone)1-Phenyl-pyrazolidin-3-one | 1-Phenyl-p...) Show SMILES O=C1CCN(N1)c1ccccc1 Show InChI InChI=1S/C9H10N2O/c12-9-6-7-11(10-9)8-4-2-1-3-5-8/h1-5H,6-7H2,(H,10,12)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibitory activity of the compound against human whole blood, LTB4 5-lipoxygenase was evaluated				Bioorg Med Chem Lett 2: 1353-1356 (1992) Article DOI: 10.1016/S0960-894X(00)80511-9 BindingDB Entry DOI: 10.7270/Q2H41RC2
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus)	BDBM50012420 (2-(4-Fluoro-phenyl)-5-methyl-thiazol-4-ol | CHEMBL...) Show SMILES Cc1sc(nc1O)-c1ccc(F)cc1 Show InChI InChI=1S/C10H8FNOS/c1-6-9(13)12-10(14-6)7-2-4-8(11)5-3-7/h2-5,13H,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	350	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description In vitro inhibition of 5-lipoxygenase (5-lo) from the 20000 g supernatant of RBI-1 cells				J Med Chem 34: 2158-65 (1991) BindingDB Entry DOI: 10.7270/Q2NS0SWM
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus)	BDBM50022683 (CHEMBL418304 | N-[1-(4-Benzyloxy-phenyl)-ethyl]-N-...) Show SMILES CC(N(O)C(C)=O)c1ccc(OCc2ccccc2)cc1 Show InChI InChI=1S/C17H19NO3/c1-13(18(20)14(2)19)16-8-10-17(11-9-16)21-12-15-6-4-3-5-7-15/h3-11,13,20H,12H2,1-2H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	370	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description In vitro inhibition of 5-lipoxygenase in RBL-1 cells				J Med Chem 31: 3-5 (1988) BindingDB Entry DOI: 10.7270/Q2V40T6C
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus)	BDBM50012392 (2-(4-Methoxy-phenyl)-5-phenyl-thiazol-4-ol | CHEMB...) Show SMILES COc1ccc(cc1)-c1nc(O)c(s1)-c1ccccc1 Show InChI InChI=1S/C16H13NO2S/c1-19-13-9-7-12(8-10-13)16-17-15(18)14(20-16)11-5-3-2-4-6-11/h2-10,18H,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	370	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description In vitro inhibition of 5-lipoxygenase (5-lo) from the 20000 g supernatant of RBI-1 cells				J Med Chem 34: 2158-65 (1991) BindingDB Entry DOI: 10.7270/Q2NS0SWM
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus)	BDBM50012381 (CHEMBL67434 | Methyl-carbamic acid 2-phenyl-5-prop...) Show SMILES CCCc1sc(nc1OC(=O)NC)-c1ccccc1 Show InChI InChI=1S/C14H16N2O2S/c1-3-7-11-12(18-14(17)15-2)16-13(19-11)10-8-5-4-6-9-10/h4-6,8-9H,3,7H2,1-2H3,(H,15,17)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	400	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of 5-lipoxygenase (5-lo) in intact rat polymorphonuclear leukocyte RPMNL				J Med Chem 34: 2158-65 (1991) BindingDB Entry DOI: 10.7270/Q2NS0SWM
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus)	BDBM32020 (4-[4-(3,4-dihydroxyphenyl)-2,3-dimethyl-butyl]pyro...) Show SMILES CC(Cc1ccc(O)c(O)c1)C(C)Cc1ccc(O)c(O)c1 Show InChI InChI=1S/C18H22O4/c1-11(7-13-3-5-15(19)17(21)9-13)12(2)8-14-4-6-16(20)18(22)10-14/h3-6,9-12,19-22H,7-8H2,1-2H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	PDB PubMed	n/a	n/a	400	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description In vitro inhibition of 5-lipoxygenase (5-lo) from the 20000 g supernatant of RBI-1 cells				J Med Chem 34: 2158-65 (1991) BindingDB Entry DOI: 10.7270/Q2NS0SWM
					More data for this Ligand-Target Pair				3D Structure (crystal)
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus)	BDBM50012389 (Acetic acid 2,5-diphenyl-thiazol-4-yl ester | CHEM...) Show SMILES CC(=O)Oc1nc(sc1-c1ccccc1)-c1ccccc1 Show InChI InChI=1S/C17H13NO2S/c1-12(19)20-16-15(13-8-4-2-5-9-13)21-17(18-16)14-10-6-3-7-11-14/h2-11H,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	400	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description In vitro inhibition of 5-lipoxygenase (5-lo) from the 20000 g supernatant of RBI-1 cells				J Med Chem 34: 2158-65 (1991) BindingDB Entry DOI: 10.7270/Q2NS0SWM
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus)	BDBM50015139 (CHEMBL67411 | N-Hydroxy-2-(6-methoxy-naphthalen-2-...) Show SMILES COc1ccc2cc(ccc2c1)C(C)C(=O)N(C)O Show InChI InChI=1S/C15H17NO3/c1-10(15(17)16(2)18)11-4-5-13-9-14(19-3)7-6-12(13)8-11/h4-10,18H,1-3H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	410	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description In vitro inhibitory activity against 5-lipoxygenase in rat RBL-1 cells				J Med Chem 30: 2121-6 (1987) BindingDB Entry DOI: 10.7270/Q29Z93XT
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid lipoxygenase ALOX15 (Homo sapiens (Human))	BDBM50009004 ((phenidone)1-Phenyl-pyrazolidin-3-one | 1-Phenyl-p...) Show SMILES O=C1CCN(N1)c1ccccc1 Show InChI InChI=1S/C9H10N2O/c12-9-6-7-11(10-9)8-4-2-1-3-5-8/h1-5H,6-7H2,(H,10,12)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article	n/a	n/a	420	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibitory activity of the compound against soyabean 15-lipoxygenase was evaluated				Bioorg Med Chem Lett 2: 1353-1356 (1992) Article DOI: 10.1016/S0960-894X(00)80511-9 BindingDB Entry DOI: 10.7270/Q2H41RC2
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus)	BDBM50023166 (CHEMBL444271 | N-Hydroxy-N-[1-(4-isobutyl-phenyl)-...) Show SMILES CC(C)Cc1ccc(cc1)C(C)N(O)C(C)=O Show InChI InChI=1S/C14H21NO2/c1-10(2)9-13-5-7-14(8-6-13)11(3)15(17)12(4)16/h5-8,10-11,17H,9H2,1-4H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	420	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description In vitro inhibition of 5-lipoxygenase in RBL-1 cells				J Med Chem 31: 3-5 (1988) BindingDB Entry DOI: 10.7270/Q2V40T6C
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Homo sapiens (Human))	BDBM50012389 (Acetic acid 2,5-diphenyl-thiazol-4-yl ester | CHEM...) Show SMILES CC(=O)Oc1nc(sc1-c1ccccc1)-c1ccccc1 Show InChI InChI=1S/C17H13NO2S/c1-12(19)20-16-15(13-8-4-2-5-9-13)21-17(18-16)14-10-6-3-7-11-14/h2-11H,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	450	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description The compound was tested for the inhibition of 5-lipoxygenase (5-lo) in human whole blood (HWBL)				J Med Chem 34: 2158-65 (1991) BindingDB Entry DOI: 10.7270/Q2NS0SWM
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus)	BDBM50012392 (2-(4-Methoxy-phenyl)-5-phenyl-thiazol-4-ol | CHEMB...) Show SMILES COc1ccc(cc1)-c1nc(O)c(s1)-c1ccccc1 Show InChI InChI=1S/C16H13NO2S/c1-19-13-9-7-12(8-10-13)16-17-15(18)14(20-16)11-5-3-2-4-6-11/h2-10,18H,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	450	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of 5-lipoxygenase (5-lo) in intact rat polymorphonuclear leukocyte RPMNL				J Med Chem 34: 2158-65 (1991) BindingDB Entry DOI: 10.7270/Q2NS0SWM
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus)	BDBM50012395 (CHEMBL68703 | Phenyl-carbamic acid 2-phenyl-5-prop...) Show SMILES CCCc1sc(nc1OC(=O)Nc1ccccc1)-c1ccccc1 Show InChI InChI=1S/C19H18N2O2S/c1-2-9-16-17(21-18(24-16)14-10-5-3-6-11-14)23-19(22)20-15-12-7-4-8-13-15/h3-8,10-13H,2,9H2,1H3,(H,20,22)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	460	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description In vitro inhibition of 5-lipoxygenase (5-lo) from the 20000 g supernatant of RBI-1 cells				J Med Chem 34: 2158-65 (1991) BindingDB Entry DOI: 10.7270/Q2NS0SWM
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Homo sapiens (Human))	BDBM50012435 (2-(4-Fluoro-phenyl)-5-phenyl-thiazol-4-ol | CHEMBL...) Show SMILES Oc1nc(sc1-c1ccccc1)-c1ccc(F)cc1 Show InChI InChI=1S/C15H10FNOS/c16-12-8-6-11(7-9-12)15-17-14(18)13(19-15)10-4-2-1-3-5-10/h1-9,18H	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	470	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description The compound was tested for the inhibition of 5-lipoxygenase (5-lo) in human whole blood (HWBL)				J Med Chem 34: 2158-65 (1991) BindingDB Entry DOI: 10.7270/Q2NS0SWM
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus)	BDBM50012410 (Acetic acid 5-butyl-2-phenyl-thiazol-4-yl ester | ...) Show SMILES CCCCc1sc(nc1OC(C)=O)-c1ccccc1 Show InChI InChI=1S/C15H17NO2S/c1-3-4-10-13-14(18-11(2)17)16-15(19-13)12-8-6-5-7-9-12/h5-9H,3-4,10H2,1-2H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	500	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of 5-lipoxygenase (5-lo) in intact rat polymorphonuclear leukocyte RPMNL				J Med Chem 34: 2158-65 (1991) BindingDB Entry DOI: 10.7270/Q2NS0SWM
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus)	BDBM50012391 (CHEMBL67589 | Hexanoic acid 2,5-diphenyl-thiazol-4...) Show SMILES CCCCCC(=O)Oc1nc(sc1-c1ccccc1)-c1ccccc1 Show InChI InChI=1S/C21H21NO2S/c1-2-3-6-15-18(23)24-20-19(16-11-7-4-8-12-16)25-21(22-20)17-13-9-5-10-14-17/h4-5,7-14H,2-3,6,15H2,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	500	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description In vitro inhibition of 5-lipoxygenase (5-lo) from the 20000 g supernatant of RBI-1 cells				J Med Chem 34: 2158-65 (1991) BindingDB Entry DOI: 10.7270/Q2NS0SWM
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus)	BDBM50012435 (2-(4-Fluoro-phenyl)-5-phenyl-thiazol-4-ol | CHEMBL...) Show SMILES Oc1nc(sc1-c1ccccc1)-c1ccc(F)cc1 Show InChI InChI=1S/C15H10FNOS/c16-12-8-6-11(7-9-12)15-17-14(18)13(19-15)10-4-2-1-3-5-10/h1-9,18H	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	500	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description In vitro inhibition of 5-lipoxygenase (5-lo) from the 20000 g supernatant of RBI-1 cells				J Med Chem 34: 2158-65 (1991) BindingDB Entry DOI: 10.7270/Q2NS0SWM
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus)	BDBM50012432 (2-(2-Fluoro-phenyl)-5-methyl-thiazol-4-ol | CHEMBL...) Show SMILES Cc1sc(nc1O)-c1ccccc1F Show InChI InChI=1S/C10H8FNOS/c1-6-9(13)12-10(14-6)7-4-2-3-5-8(7)11/h2-5,13H,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	500	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description In vitro inhibition of 5-lipoxygenase (5-lo) from the 20000 g supernatant of RBI-1 cells				J Med Chem 34: 2158-65 (1991) BindingDB Entry DOI: 10.7270/Q2NS0SWM
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus)	BDBM50012387 (2-(4-Bromo-phenyl)-5-methyl-thiazol-4-ol | CHEMBL3...) Show SMILES Cc1sc(nc1O)-c1ccc(Br)cc1 Show InChI InChI=1S/C10H8BrNOS/c1-6-9(13)12-10(14-6)7-2-4-8(11)5-3-7/h2-5,13H,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	510	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description In vitro inhibition of 5-lipoxygenase (5-lo) from the 20000 g supernatant of RBI-1 cells				J Med Chem 34: 2158-65 (1991) BindingDB Entry DOI: 10.7270/Q2NS0SWM
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus)	BDBM50009004 ((phenidone)1-Phenyl-pyrazolidin-3-one | 1-Phenyl-p...) Show SMILES O=C1CCN(N1)c1ccccc1 Show InChI InChI=1S/C9H10N2O/c12-9-6-7-11(10-9)8-4-2-1-3-5-8/h1-5H,6-7H2,(H,10,12)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article	n/a	n/a	520	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibitory activity of the compound against intact rat PMNL, LTB4 5-lipoxygenase was evaluated				Bioorg Med Chem Lett 2: 1353-1356 (1992) Article DOI: 10.1016/S0960-894X(00)80511-9 BindingDB Entry DOI: 10.7270/Q2H41RC2
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus)	BDBM50009004 ((phenidone)1-Phenyl-pyrazolidin-3-one | 1-Phenyl-p...) Show SMILES O=C1CCN(N1)c1ccccc1 Show InChI InChI=1S/C9H10N2O/c12-9-6-7-11(10-9)8-4-2-1-3-5-8/h1-5H,6-7H2,(H,10,12)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article	n/a	n/a	520	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibitory activity of the compound against intact rat PMNL, LTB4 5-lipoxygenase was evaluated				Bioorg Med Chem Lett 2: 1353-1356 (1992) Article DOI: 10.1016/S0960-894X(00)80511-9 BindingDB Entry DOI: 10.7270/Q2H41RC2
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus)	BDBM50012428 (2,5-Diphenyl-thiazol-4-ol | CHEMBL308001) Show SMILES Oc1nc(sc1-c1ccccc1)-c1ccccc1 Show InChI InChI=1S/C15H11NOS/c17-14-13(11-7-3-1-4-8-11)18-15(16-14)12-9-5-2-6-10-12/h1-10,17H	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	530	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description In vitro inhibition of 5-lipoxygenase (5-lo) from the 20000 g supernatant of RBI-1 cells				J Med Chem 34: 2158-65 (1991) BindingDB Entry DOI: 10.7270/Q2NS0SWM
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus)	BDBM50012407 (Acetic acid 2-phenyl-5-propyl-thiazol-4-yl ester |...) Show SMILES CCCc1sc(nc1OC(C)=O)-c1ccccc1 Show InChI InChI=1S/C14H15NO2S/c1-3-7-12-13(17-10(2)16)15-14(18-12)11-8-5-4-6-9-11/h4-6,8-9H,3,7H2,1-2H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	530	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description In vitro inhibition of 5-lipoxygenase (5-lo) from the 20000 g supernatant of RBI-1 cells				J Med Chem 34: 2158-65 (1991) BindingDB Entry DOI: 10.7270/Q2NS0SWM
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus)	BDBM50023167 (CHEMBL146487 | N-Hydroxy-N-(1-naphthalen-2-yl-ethy...) Show SMILES CC(N(O)C(C)=O)c1ccc2ccccc2c1 Show InChI InChI=1S/C14H15NO2/c1-10(15(17)11(2)16)13-8-7-12-5-3-4-6-14(12)9-13/h3-10,17H,1-2H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	540	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description In vitro inhibition of 5-lipoxygenase in RBL-1 cells				J Med Chem 31: 3-5 (1988) BindingDB Entry DOI: 10.7270/Q2V40T6C
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus)	BDBM50012405 (5-Phenyl-2-pyridin-4-yl-thiazol-4-ol | CHEMBL30407...) Show SMILES Oc1nc(sc1-c1ccccc1)-c1ccncc1 Show InChI InChI=1S/C14H10N2OS/c17-13-12(10-4-2-1-3-5-10)18-14(16-13)11-6-8-15-9-7-11/h1-9,17H	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	540	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description In vitro inhibition of 5-lipoxygenase (5-lo) from the 20000 g supernatant of RBI-1 cells				J Med Chem 34: 2158-65 (1991) BindingDB Entry DOI: 10.7270/Q2NS0SWM
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus)	BDBM50012382 (2-(4-Chloro-phenyl)-5-methyl-thiazol-4-ol | CHEMBL...) Show SMILES Cc1sc(nc1O)-c1ccc(Cl)cc1 Show InChI InChI=1S/C10H8ClNOS/c1-6-9(13)12-10(14-6)7-2-4-8(11)5-3-7/h2-5,13H,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	570	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description In vitro inhibition of 5-lipoxygenase (5-lo) from the 20000 g supernatant of RBI-1 cells				J Med Chem 34: 2158-65 (1991) BindingDB Entry DOI: 10.7270/Q2NS0SWM
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus)	BDBM50012377 (2-Phenyl-5-propyl-thiazol-4-ol | CHEMBL69213) Show SMILES CCCc1sc(nc1O)-c1ccccc1 Show InChI InChI=1S/C12H13NOS/c1-2-6-10-11(14)13-12(15-10)9-7-4-3-5-8-9/h3-5,7-8,14H,2,6H2,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	580	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description In vitro inhibition of 5-lipoxygenase (5-lo) from the 20000 g supernatant of RBI-1 cells				J Med Chem 34: 2158-65 (1991) BindingDB Entry DOI: 10.7270/Q2NS0SWM
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus)	BDBM50015138 (CHEMBL146477 | N-Hydroxy-N-methyl-2-naphthalen-2-y...) Show SMILES CC(C(=O)N(C)O)c1ccc2ccccc2c1 Show InChI InChI=1S/C14H15NO2/c1-10(14(16)15(2)17)12-8-7-11-5-3-4-6-13(11)9-12/h3-10,17H,1-2H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	590	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description In vitro inhibition of 5-lipoxygenase in RBL-1 cells				J Med Chem 31: 3-5 (1988) BindingDB Entry DOI: 10.7270/Q2V40T6C
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus)	BDBM50000541 ((+-)-1-(1-Benzo[b]thien-2-ylethyl)-1-hydroxyurea |...) Show SMILES CC(N(O)C(N)=O)c1cc2ccccc2s1 Show InChI InChI=1S/C11H12N2O2S/c1-7(13(15)11(12)14)10-6-8-4-2-3-5-9(8)16-10/h2-7,15H,1H3,(H2,12,14)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	600	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description In vitro inhibition of 5-lipoxygenase (5-lo) from the 20000 g supernatant of RBI-1 cells				J Med Chem 34: 2158-65 (1991) BindingDB Entry DOI: 10.7270/Q2NS0SWM
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus)	BDBM50012393 (5-Methyl-2-p-tolyl-thiazol-4-ol | CHEMBL69094) Show SMILES Cc1sc(nc1O)-c1ccc(C)cc1 Show InChI InChI=1S/C11H11NOS/c1-7-3-5-9(6-4-7)11-12-10(13)8(2)14-11/h3-6,13H,1-2H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	630	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description In vitro inhibition of 5-lipoxygenase (5-lo) from the 20000 g supernatant of RBI-1 cells				J Med Chem 34: 2158-65 (1991) BindingDB Entry DOI: 10.7270/Q2NS0SWM
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus)	BDBM50012407 (Acetic acid 2-phenyl-5-propyl-thiazol-4-yl ester |...) Show SMILES CCCc1sc(nc1OC(C)=O)-c1ccccc1 Show InChI InChI=1S/C14H15NO2S/c1-3-7-12-13(17-10(2)16)15-14(18-12)11-8-5-4-6-9-11/h4-6,8-9H,3,7H2,1-2H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	660	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description In vitro inhibition of 5-lipoxygenase (5-lo) from the 20000 g supernatant of RBI-1 cells				J Med Chem 34: 2158-65 (1991) BindingDB Entry DOI: 10.7270/Q2NS0SWM
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus)	BDBM50012413 (2-(3-Fluoro-phenyl)-5-methyl-thiazol-4-ol | CHEMBL...) Show SMILES Cc1sc(nc1O)-c1cccc(F)c1 Show InChI InChI=1S/C10H8FNOS/c1-6-9(13)12-10(14-6)7-3-2-4-8(11)5-7/h2-5,13H,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	660	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description In vitro inhibition of 5-lipoxygenase (5-lo) from the 20000 g supernatant of RBI-1 cells				J Med Chem 34: 2158-65 (1991) BindingDB Entry DOI: 10.7270/Q2NS0SWM
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus)	BDBM50012429 (5-Phenethyl-2-phenyl-thiazol-4-ol | CHEMBL302965) Show SMILES Oc1nc(sc1CCc1ccccc1)-c1ccccc1 Show InChI InChI=1S/C17H15NOS/c19-16-15(12-11-13-7-3-1-4-8-13)20-17(18-16)14-9-5-2-6-10-14/h1-10,19H,11-12H2	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	690	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description In vitro inhibition of 5-lipoxygenase (5-lo) from the 20000 g supernatant of RBI-1 cells				J Med Chem 34: 2158-65 (1991) BindingDB Entry DOI: 10.7270/Q2NS0SWM
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus)	BDBM50012404 (2-Methyl-5-phenyl-thiazol-4-ol | CHEMBL69093) Show SMILES Cc1nc(O)c(s1)-c1ccccc1 Show InChI InChI=1S/C10H9NOS/c1-7-11-10(12)9(13-7)8-5-3-2-4-6-8/h2-6,12H,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	700	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description In vitro inhibition of 5-lipoxygenase (5-lo) from the 20000 g supernatant of RBI-1 cells				J Med Chem 34: 2158-65 (1991) BindingDB Entry DOI: 10.7270/Q2NS0SWM
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus)	BDBM50012398 (4-(4-Hydroxy-5-methyl-thiazol-2-yl)-benzonitrile |...) Show SMILES Cc1sc(nc1O)-c1ccc(cc1)C#N Show InChI InChI=1S/C11H8N2OS/c1-7-10(14)13-11(15-7)9-4-2-8(6-12)3-5-9/h2-5,14H,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	700	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description In vitro inhibition of 5-lipoxygenase (5-lo) from the 20000 g supernatant of RBI-1 cells				J Med Chem 34: 2158-65 (1991) BindingDB Entry DOI: 10.7270/Q2NS0SWM
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus)	BDBM50012375 (CHEMBL303632 | Carbonic acid ethyl ester 2-phenyl-...) Show SMILES CCCc1sc(nc1OC(=O)OCC)-c1ccccc1 Show InChI InChI=1S/C15H17NO3S/c1-3-8-12-13(19-15(17)18-4-2)16-14(20-12)11-9-6-5-7-10-11/h5-7,9-10H,3-4,8H2,1-2H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	700	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of 5-lipoxygenase (5-lo) in intact rat polymorphonuclear leukocyte RPMNL				J Med Chem 34: 2158-65 (1991) BindingDB Entry DOI: 10.7270/Q2NS0SWM
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus)	BDBM50012385 (4-(4-Hydroxy-5-methyl-thiazol-2-yl)-benzoic acid e...) Show SMILES CCOC(=O)c1ccc(cc1)-c1nc(O)c(C)s1 Show InChI InChI=1S/C13H13NO3S/c1-3-17-13(16)10-6-4-9(5-7-10)12-14-11(15)8(2)18-12/h4-7,15H,3H2,1-2H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	710	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description In vitro inhibition of 5-lipoxygenase (5-lo) from the 20000 g supernatant of RBI-1 cells				J Med Chem 34: 2158-65 (1991) BindingDB Entry DOI: 10.7270/Q2NS0SWM
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus)	BDBM50015092 (2-(4-Butoxy-phenyl)-N-hydroxy-N-methyl-propionamid...) Show SMILES CCCCOc1ccc(cc1)C(C)C(=O)N(C)O Show InChI InChI=1S/C14H21NO3/c1-4-5-10-18-13-8-6-12(7-9-13)11(2)14(16)15(3)17/h6-9,11,17H,4-5,10H2,1-3H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	730	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description In vitro inhibitory activity against 5-lipoxygenase in rat RBL-1 cells				J Med Chem 30: 2121-6 (1987) BindingDB Entry DOI: 10.7270/Q29Z93XT
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Homo sapiens (Human))	BDBM50280197 (1-(3-Chloro-phenyl)-pyrazolidin-3-one | CHEMBL3024...) Show SMILES Clc1cccc(c1)N1CCC(=O)N1 Show InChI InChI=1S/C9H9ClN2O/c10-7-2-1-3-8(6-7)12-5-4-9(13)11-12/h1-3,6H,4-5H2,(H,11,13)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article	n/a	n/a	730	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibitory activity against 5-lipoxygenase.				Bioorg Med Chem Lett 2: 1357-1360 (1992) Article DOI: 10.1016/S0960-894X(00)80512-0 BindingDB Entry DOI: 10.7270/Q2CC10M8
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Homo sapiens (Human))	BDBM50012425 (5-Phenyl-2-p-tolyl-thiazol-4-ol | CHEMBL67708) Show SMILES Cc1ccc(cc1)-c1nc(O)c(s1)-c1ccccc1 Show InChI InChI=1S/C16H13NOS/c1-11-7-9-13(10-8-11)16-17-15(18)14(19-16)12-5-3-2-4-6-12/h2-10,18H,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	740	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description The compound was tested for the inhibition of 5-lipoxygenase (5-lo) in human whole blood (HWBL)				J Med Chem 34: 2158-65 (1991) BindingDB Entry DOI: 10.7270/Q2NS0SWM
					More data for this Ligand-Target Pair

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