BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 99 hits with Last Name = 'maclntyre' and Initial = 'e'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Melanocortin receptor 4


(Homo sapiens (Human))
BDBM50168724
PNG
(1-[(R)-2-[((1S,2S)-1-Amino-1,2,3,4-tetrahydro-naph...)
Show SMILES CC(C)(C)NC(=O)C1(CCN(CC1)C(=O)[C@@H](Cc1ccc(Cl)cc1)NC(=O)[C@H]1CCc2ccccc2[C@H]1N)C1CCCCC1
Show InChI InChI=1S/C36H49ClN4O3/c1-35(2,3)40-34(44)36(26-10-5-4-6-11-26)19-21-41(22-20-36)33(43)30(23-24-13-16-27(37)17-14-24)39-32(42)29-18-15-25-9-7-8-12-28(25)31(29)38/h7-9,12-14,16-17,26,29-31H,4-6,10-11,15,18-23,38H2,1-3H3,(H,39,42)(H,40,44)/t29-,30+,31+/m0/s1
PDB

KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 0.370n/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Concentration required for 50% inhibition by displacement of of [125I]NDP-alpha-MSH of human MC4R expressed in CHO cells


Bioorg Med Chem Lett 15: 3430-3 (2005)


Article DOI: 10.1016/j.bmcl.2005.05.012
BindingDB Entry DOI: 10.7270/Q2959H2N
More data for this
Ligand-Target Pair
Melanocortin receptor 4


(Homo sapiens (Human))
BDBM50168725
PNG
(1-[2-[((R)-3-Amino-1,2,3,4-tetrahydro-naphthalene-...)
Show SMILES CC(C)(C)NC(=O)C1(CCN(CC1)C(=O)[C@@H](Cc1ccc(Cl)cc1)NC(=O)C1Cc2ccccc2CC1N)C1CCCCC1
Show InChI InChI=1S/C36H49ClN4O3/c1-35(2,3)40-34(44)36(27-11-5-4-6-12-27)17-19-41(20-18-36)33(43)31(21-24-13-15-28(37)16-14-24)39-32(42)29-22-25-9-7-8-10-26(25)23-30(29)38/h7-10,13-16,27,29-31H,4-6,11-12,17-23,38H2,1-3H3,(H,39,42)(H,40,44)/t29?,30?,31-/m1/s1
PDB

KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 0.560n/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Concentration required for 50% inhibition by displacement of of [125I]NDP-alpha-MSH of human MC4R expressed in CHO cells


Bioorg Med Chem Lett 15: 3430-3 (2005)


Article DOI: 10.1016/j.bmcl.2005.05.012
BindingDB Entry DOI: 10.7270/Q2959H2N
More data for this
Ligand-Target Pair
Melanocortin receptor 4


(Homo sapiens (Human))
BDBM50168726
PNG
(1-[(R)-2-[((1R,2R)-1-Amino-1,2,3,4-tetrahydro-naph...)
Show SMILES CC(C)(C)NC(=O)C1(CCN(CC1)C(=O)[C@@H](Cc1ccc(Cl)cc1)NC(=O)[C@@H]1CCc2ccccc2[C@@H]1N)C1CCCCC1
Show InChI InChI=1S/C36H49ClN4O3/c1-35(2,3)40-34(44)36(26-10-5-4-6-11-26)19-21-41(22-20-36)33(43)30(23-24-13-16-27(37)17-14-24)39-32(42)29-18-15-25-9-7-8-12-28(25)31(29)38/h7-9,12-14,16-17,26,29-31H,4-6,10-11,15,18-23,38H2,1-3H3,(H,39,42)(H,40,44)/t29-,30-,31+/m1/s1
PDB

KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 0.770n/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Concentration required for 50% inhibition by displacement of of [125I]NDP-alpha-MSH of human MC4R expressed in CHO cells


Bioorg Med Chem Lett 15: 3430-3 (2005)


Article DOI: 10.1016/j.bmcl.2005.05.012
BindingDB Entry DOI: 10.7270/Q2959H2N
More data for this
Ligand-Target Pair
Melanocortin receptor 4


(Homo sapiens (Human))
BDBM50024350
PNG
(CHEMBL2113041)
Show SMILES CC(C)(C)NC(=O)C1(CCN(CC1)C(=O)[C@@H](Cc1ccc(Cl)cc1)NC(=O)C1CCCc2ccccc2C1N)C1CCCCC1
Show InChI InChI=1S/C37H51ClN4O3/c1-36(2,3)41-35(45)37(27-12-5-4-6-13-27)20-22-42(23-21-37)34(44)31(24-25-16-18-28(38)19-17-25)40-33(43)30-15-9-11-26-10-7-8-14-29(26)32(30)39/h7-8,10,14,16-19,27,30-32H,4-6,9,11-13,15,20-24,39H2,1-3H3,(H,40,43)(H,41,45)/t30?,31-,32?/m1/s1
PDB

KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 1.10n/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Concentration required for 50% inhibition by displacement of of [125I]NDP-alpha-MSH of human MC4R expressed in CHO cells


Bioorg Med Chem Lett 15: 3430-3 (2005)


Article DOI: 10.1016/j.bmcl.2005.05.012
BindingDB Entry DOI: 10.7270/Q2959H2N
More data for this
Ligand-Target Pair
Melanocortin receptor 4


(Homo sapiens (Human))
BDBM50168727
PNG
(1-[(R)-2-[((1S,2S)-1-Amino-1-methyl-1,2,3,4-tetrah...)
Show SMILES CC(C)(C)NC(=O)C1(CCN(CC1)C(=O)[C@@H](Cc1ccc(Cl)cc1)NC(=O)[C@H]1CCc2ccccc2[C@@]1(C)N)C1CCCCC1
Show InChI InChI=1S/C37H51ClN4O3/c1-35(2,3)41-34(45)37(27-11-6-5-7-12-27)20-22-42(23-21-37)33(44)31(24-25-14-17-28(38)18-15-25)40-32(43)30-19-16-26-10-8-9-13-29(26)36(30,4)39/h8-10,13-15,17-18,27,30-31H,5-7,11-12,16,19-24,39H2,1-4H3,(H,40,43)(H,41,45)/t30-,31-,36-/m1/s1
PDB

KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 1.10n/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Concentration required for 50% inhibition by displacement of of [125I]NDP-alpha-MSH of human MC4R expressed in CHO cells


Bioorg Med Chem Lett 15: 3430-3 (2005)


Article DOI: 10.1016/j.bmcl.2005.05.012
BindingDB Entry DOI: 10.7270/Q2959H2N
More data for this
Ligand-Target Pair
Melanocortin receptor 4


(Homo sapiens (Human))
BDBM50119368
PNG
((R)-1,2,3,4-Tetrahydro-isoquinoline-3-carboxylic a...)
Show SMILES Clc1ccc(C[C@@H](NC(=O)[C@H]2Cc3ccccc3CN2)C(=O)N2CCC(Cn3cncn3)(CC2)C2CCCCC2)cc1
Show InChI InChI=1S/C33H41ClN6O2/c34-28-12-10-24(11-13-28)18-30(38-31(41)29-19-25-6-4-5-7-26(25)20-36-29)32(42)39-16-14-33(15-17-39,21-40-23-35-22-37-40)27-8-2-1-3-9-27/h4-7,10-13,22-23,27,29-30,36H,1-3,8-9,14-21H2,(H,38,41)/t29-,30-/m1/s1
PDB

KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
Purchase

CHEMBL
MCE
PC cid
PC sid
PDB
UniChem

Patents


Similars

PDB
Article
PubMed
n/an/a 1.20n/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Concentration required for 50% inhibition by displacement of of [125I]NDP-alpha-MSH of human MC4R expressed in CHO cells


Bioorg Med Chem Lett 15: 3430-3 (2005)


Article DOI: 10.1016/j.bmcl.2005.05.012
BindingDB Entry DOI: 10.7270/Q2959H2N
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
Melanocortin receptor 4


(Homo sapiens (Human))
BDBM50168723
PNG
(1-[2-[((R)-1-Amino-indane-2-carbonyl)-amino]-3-(4-...)
Show SMILES CC(C)(C)NC(=O)C1(CCN(CC1)C(=O)[C@@H](Cc1ccc(Cl)cc1)NC(=O)C1Cc2ccccc2C1N)C1CCCCC1
Show InChI InChI=1S/C35H47ClN4O3/c1-34(2,3)39-33(43)35(25-10-5-4-6-11-25)17-19-40(20-18-35)32(42)29(21-23-13-15-26(36)16-14-23)38-31(41)28-22-24-9-7-8-12-27(24)30(28)37/h7-9,12-16,25,28-30H,4-6,10-11,17-22,37H2,1-3H3,(H,38,41)(H,39,43)/t28?,29-,30?/m1/s1
PDB

KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 1.90n/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Concentration required for 50% inhibition by displacement of of [125I]NDP-alpha-MSH of human MC4R expressed in CHO cells


Bioorg Med Chem Lett 15: 3430-3 (2005)


Article DOI: 10.1016/j.bmcl.2005.05.012
BindingDB Entry DOI: 10.7270/Q2959H2N
More data for this
Ligand-Target Pair
Melanocortin receptor 4


(Homo sapiens (Human))
BDBM50323150
PNG
(CHEMBL1209253 | N-(2-(4-((3S,4R)-1-tert-butyl-4-(2...)
Show SMILES CC(C)N(CC(C1CCCCC1)N1CCN(CC1)C(=O)[C@@H]1CN(C[C@H]1c1ccc(F)cc1F)C(C)(C)C)S(C)(=O)=O |r|
Show InChI InChI=1S/C31H50F2N4O3S/c1-22(2)37(41(6,39)40)21-29(23-10-8-7-9-11-23)34-14-16-35(17-15-34)30(38)27-20-36(31(3,4)5)19-26(27)25-13-12-24(32)18-28(25)33/h12-13,18,22-23,26-27,29H,7-11,14-17,19-21H2,1-6H3/t26-,27+,29?/m0/s1
PDB

KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 13n/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Agonist activity at human MC4 receptor expressed in CHO cells assessed as increase of alpha-MSH-induced cAMP accumulation


Bioorg Med Chem Lett 20: 4483-6 (2010)


Article DOI: 10.1016/j.bmcl.2010.06.038
BindingDB Entry DOI: 10.7270/Q2C829GJ
More data for this
Ligand-Target Pair
Melanocortin receptor 4


(Homo sapiens (Human))
BDBM50323150
PNG
(CHEMBL1209253 | N-(2-(4-((3S,4R)-1-tert-butyl-4-(2...)
Show SMILES CC(C)N(CC(C1CCCCC1)N1CCN(CC1)C(=O)[C@@H]1CN(C[C@H]1c1ccc(F)cc1F)C(C)(C)C)S(C)(=O)=O |r|
Show InChI InChI=1S/C31H50F2N4O3S/c1-22(2)37(41(6,39)40)21-29(23-10-8-7-9-11-23)34-14-16-35(17-15-34)30(38)27-20-36(31(3,4)5)19-26(27)25-13-12-24(32)18-28(25)33/h12-13,18,22-23,26-27,29H,7-11,14-17,19-21H2,1-6H3/t26-,27+,29?/m0/s1
PDB

KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 13n/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Displacement of [125I]NDP-alpha-MSH from human MC4 receptor expressed in CHO cells


Bioorg Med Chem Lett 20: 4483-6 (2010)


Article DOI: 10.1016/j.bmcl.2010.06.038
BindingDB Entry DOI: 10.7270/Q2C829GJ
More data for this
Ligand-Target Pair
Melanocortin receptor 4


(Homo sapiens (Human))
BDBM50323159
PNG
(CHEMBL1209321 | N-(2-(4-((3S,4R)-1-tert-butyl-4-(2...)
Show SMILES CC(C)CC(CN(C(C)C)C(C)=O)N1CCN(CC1)C(=O)[C@@H]1CN(C[C@H]1c1ccc(F)cc1F)C(C)(C)C |r|
Show InChI InChI=1S/C30H48F2N4O2/c1-20(2)15-24(17-36(21(3)4)22(5)37)33-11-13-34(14-12-33)29(38)27-19-35(30(6,7)8)18-26(27)25-10-9-23(31)16-28(25)32/h9-10,16,20-21,24,26-27H,11-15,17-19H2,1-8H3/t24?,26-,27+/m0/s1
PDB

KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 23n/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Displacement of [125I]NDP-alpha-MSH from human MC4 receptor expressed in CHO cells


Bioorg Med Chem Lett 20: 4483-6 (2010)


Article DOI: 10.1016/j.bmcl.2010.06.038
BindingDB Entry DOI: 10.7270/Q2C829GJ
More data for this
Ligand-Target Pair
Melanocortin receptor 4


(Homo sapiens (Human))
BDBM50323159
PNG
(CHEMBL1209321 | N-(2-(4-((3S,4R)-1-tert-butyl-4-(2...)
Show SMILES CC(C)CC(CN(C(C)C)C(C)=O)N1CCN(CC1)C(=O)[C@@H]1CN(C[C@H]1c1ccc(F)cc1F)C(C)(C)C |r|
Show InChI InChI=1S/C30H48F2N4O2/c1-20(2)15-24(17-36(21(3)4)22(5)37)33-11-13-34(14-12-33)29(38)27-19-35(30(6,7)8)18-26(27)25-10-9-23(31)16-28(25)32/h9-10,16,20-21,24,26-27H,11-15,17-19H2,1-8H3/t24?,26-,27+/m0/s1
PDB

KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 23n/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Agonist activity at human MC4 receptor expressed in CHO cells assessed as increase of alpha-MSH-induced cAMP accumulation


Bioorg Med Chem Lett 20: 4483-6 (2010)


Article DOI: 10.1016/j.bmcl.2010.06.038
BindingDB Entry DOI: 10.7270/Q2C829GJ
More data for this
Ligand-Target Pair
Melanocortin receptor 5


(Homo sapiens (Human))
BDBM50168726
PNG
(1-[(R)-2-[((1R,2R)-1-Amino-1,2,3,4-tetrahydro-naph...)
Show SMILES CC(C)(C)NC(=O)C1(CCN(CC1)C(=O)[C@@H](Cc1ccc(Cl)cc1)NC(=O)[C@@H]1CCc2ccccc2[C@@H]1N)C1CCCCC1
Show InChI InChI=1S/C36H49ClN4O3/c1-35(2,3)40-34(44)36(26-10-5-4-6-11-26)19-21-41(22-20-36)33(43)30(23-24-13-16-27(37)17-14-24)39-32(42)29-18-15-25-9-7-8-12-28(25)31(29)38/h7-9,12-14,16-17,26,29-31H,4-6,10-11,15,18-23,38H2,1-3H3,(H,39,42)(H,40,44)/t29-,30-,31+/m1/s1
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 24n/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Concentration required for 50% inhibition by displacement of of [125I]NDP-alpha-MSH of human MC5R expressed in CHO cells


Bioorg Med Chem Lett 15: 3430-3 (2005)


Article DOI: 10.1016/j.bmcl.2005.05.012
BindingDB Entry DOI: 10.7270/Q2959H2N
More data for this
Ligand-Target Pair
Melanocortin receptor 4


(Homo sapiens (Human))
BDBM50323158
PNG
(CHEMBL1209382 | N-(2-(4-((3S,4R)-1-tert-butyl-4-(2...)
Show SMILES CC(C)CC(CN(C(C)C)S(C)(=O)=O)N1CCN(CC1)C(=O)[C@@H]1CN(C[C@H]1c1ccc(F)cc1F)C(C)(C)C |r|
Show InChI InChI=1S/C29H48F2N4O3S/c1-20(2)15-23(17-35(21(3)4)39(8,37)38)32-11-13-33(14-12-32)28(36)26-19-34(29(5,6)7)18-25(26)24-10-9-22(30)16-27(24)31/h9-10,16,20-21,23,25-26H,11-15,17-19H2,1-8H3/t23?,25-,26+/m0/s1
PDB

KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 27n/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Displacement of [125I]NDP-alpha-MSH from human MC4 receptor expressed in CHO cells


Bioorg Med Chem Lett 20: 4483-6 (2010)


Article DOI: 10.1016/j.bmcl.2010.06.038
BindingDB Entry DOI: 10.7270/Q2C829GJ
More data for this
Ligand-Target Pair
Melanocortin receptor 4


(Homo sapiens (Human))
BDBM50323158
PNG
(CHEMBL1209382 | N-(2-(4-((3S,4R)-1-tert-butyl-4-(2...)
Show SMILES CC(C)CC(CN(C(C)C)S(C)(=O)=O)N1CCN(CC1)C(=O)[C@@H]1CN(C[C@H]1c1ccc(F)cc1F)C(C)(C)C |r|
Show InChI InChI=1S/C29H48F2N4O3S/c1-20(2)15-23(17-35(21(3)4)39(8,37)38)32-11-13-33(14-12-32)28(36)26-19-34(29(5,6)7)18-25(26)24-10-9-22(30)16-27(24)31/h9-10,16,20-21,23,25-26H,11-15,17-19H2,1-8H3/t23?,25-,26+/m0/s1
PDB

KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 27n/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Agonist activity at human MC4 receptor expressed in CHO cells assessed as increase of alpha-MSH-induced cAMP accumulation


Bioorg Med Chem Lett 20: 4483-6 (2010)


Article DOI: 10.1016/j.bmcl.2010.06.038
BindingDB Entry DOI: 10.7270/Q2C829GJ
More data for this
Ligand-Target Pair
Melanocortin receptor 4


(Homo sapiens (Human))
BDBM50323151
PNG
(CHEMBL1209252 | N-(2-(4-((3S,4R)-1-tert-butyl-4-(2...)
Show SMILES CC(C)N(CC(C1CCCCC1)N1CCN(CC1)C(=O)[C@@H]1CN(C[C@H]1c1ccc(F)cc1F)C(C)(C)C)C(C)=O |r|
Show InChI InChI=1S/C32H50F2N4O2/c1-22(2)38(23(3)39)21-30(24-10-8-7-9-11-24)35-14-16-36(17-15-35)31(40)28-20-37(32(4,5)6)19-27(28)26-13-12-25(33)18-29(26)34/h12-13,18,22,24,27-28,30H,7-11,14-17,19-21H2,1-6H3/t27-,28+,30?/m0/s1
PDB

KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 29n/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Agonist activity at human MC4 receptor expressed in CHO cells assessed as increase of alpha-MSH-induced cAMP accumulation


Bioorg Med Chem Lett 20: 4483-6 (2010)


Article DOI: 10.1016/j.bmcl.2010.06.038
BindingDB Entry DOI: 10.7270/Q2C829GJ
More data for this
Ligand-Target Pair
Melanocortin receptor 4


(Homo sapiens (Human))
BDBM50323151
PNG
(CHEMBL1209252 | N-(2-(4-((3S,4R)-1-tert-butyl-4-(2...)
Show SMILES CC(C)N(CC(C1CCCCC1)N1CCN(CC1)C(=O)[C@@H]1CN(C[C@H]1c1ccc(F)cc1F)C(C)(C)C)C(C)=O |r|
Show InChI InChI=1S/C32H50F2N4O2/c1-22(2)38(23(3)39)21-30(24-10-8-7-9-11-24)35-14-16-36(17-15-35)31(40)28-20-37(32(4,5)6)19-27(28)26-13-12-25(33)18-29(26)34/h12-13,18,22,24,27-28,30H,7-11,14-17,19-21H2,1-6H3/t27-,28+,30?/m0/s1
PDB

KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 29n/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Displacement of [125I]NDP-alpha-MSH from human MC4 receptor expressed in CHO cells


Bioorg Med Chem Lett 20: 4483-6 (2010)


Article DOI: 10.1016/j.bmcl.2010.06.038
BindingDB Entry DOI: 10.7270/Q2C829GJ
More data for this
Ligand-Target Pair
Melanocortin receptor 5


(Homo sapiens (Human))
BDBM50168727
PNG
(1-[(R)-2-[((1S,2S)-1-Amino-1-methyl-1,2,3,4-tetrah...)
Show SMILES CC(C)(C)NC(=O)C1(CCN(CC1)C(=O)[C@@H](Cc1ccc(Cl)cc1)NC(=O)[C@H]1CCc2ccccc2[C@@]1(C)N)C1CCCCC1
Show InChI InChI=1S/C37H51ClN4O3/c1-35(2,3)41-34(45)37(27-11-6-5-7-12-27)20-22-42(23-21-37)33(44)31(24-25-14-17-28(38)18-15-25)40-32(43)30-19-16-26-10-8-9-13-29(26)36(30,4)39/h8-10,13-15,17-18,27,30-31H,5-7,11-12,16,19-24,39H2,1-4H3,(H,40,43)(H,41,45)/t30-,31-,36-/m1/s1
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 31n/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Concentration required for 50% inhibition by displacement of of [125I]NDP-alpha-MSH of human MC5R expressed in CHO cells


Bioorg Med Chem Lett 15: 3430-3 (2005)


Article DOI: 10.1016/j.bmcl.2005.05.012
BindingDB Entry DOI: 10.7270/Q2959H2N
More data for this
Ligand-Target Pair
Melanocortin receptor 3


(Homo sapiens (Human))
BDBM50168726
PNG
(1-[(R)-2-[((1R,2R)-1-Amino-1,2,3,4-tetrahydro-naph...)
Show SMILES CC(C)(C)NC(=O)C1(CCN(CC1)C(=O)[C@@H](Cc1ccc(Cl)cc1)NC(=O)[C@@H]1CCc2ccccc2[C@@H]1N)C1CCCCC1
Show InChI InChI=1S/C36H49ClN4O3/c1-35(2,3)40-34(44)36(26-10-5-4-6-11-26)19-21-41(22-20-36)33(43)30(23-24-13-16-27(37)17-14-24)39-32(42)29-18-15-25-9-7-8-12-28(25)31(29)38/h7-9,12-14,16-17,26,29-31H,4-6,10-11,15,18-23,38H2,1-3H3,(H,39,42)(H,40,44)/t29-,30-,31+/m1/s1
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 32n/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Concentration required for 50% inhibition by displacement of of [125I]NDP-alpha-MSH of human MC3R expressed in CHO cells


Bioorg Med Chem Lett 15: 3430-3 (2005)


Article DOI: 10.1016/j.bmcl.2005.05.012
BindingDB Entry DOI: 10.7270/Q2959H2N
More data for this
Ligand-Target Pair
Melanocortin receptor 5


(Homo sapiens (Human))
BDBM50168723
PNG
(1-[2-[((R)-1-Amino-indane-2-carbonyl)-amino]-3-(4-...)
Show SMILES CC(C)(C)NC(=O)C1(CCN(CC1)C(=O)[C@@H](Cc1ccc(Cl)cc1)NC(=O)C1Cc2ccccc2C1N)C1CCCCC1
Show InChI InChI=1S/C35H47ClN4O3/c1-34(2,3)39-33(43)35(25-10-5-4-6-11-25)17-19-40(20-18-35)32(42)29(21-23-13-15-26(36)16-14-23)38-31(41)28-22-24-9-7-8-12-27(24)30(28)37/h7-9,12-16,25,28-30H,4-6,10-11,17-22,37H2,1-3H3,(H,38,41)(H,39,43)/t28?,29-,30?/m1/s1
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 34n/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Concentration required for 50% inhibition by displacement of of [125I]NDP-alpha-MSH of human MC5R expressed in CHO cells


Bioorg Med Chem Lett 15: 3430-3 (2005)


Article DOI: 10.1016/j.bmcl.2005.05.012
BindingDB Entry DOI: 10.7270/Q2959H2N
More data for this
Ligand-Target Pair
Melanocortin receptor 5


(Homo sapiens (Human))
BDBM50168725
PNG
(1-[2-[((R)-3-Amino-1,2,3,4-tetrahydro-naphthalene-...)
Show SMILES CC(C)(C)NC(=O)C1(CCN(CC1)C(=O)[C@@H](Cc1ccc(Cl)cc1)NC(=O)C1Cc2ccccc2CC1N)C1CCCCC1
Show InChI InChI=1S/C36H49ClN4O3/c1-35(2,3)40-34(44)36(27-11-5-4-6-12-27)17-19-41(20-18-36)33(43)31(21-24-13-15-28(37)16-14-24)39-32(42)29-22-25-9-7-8-10-26(25)23-30(29)38/h7-10,13-16,27,29-31H,4-6,11-12,17-23,38H2,1-3H3,(H,39,42)(H,40,44)/t29?,30?,31-/m1/s1
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 40n/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Concentration required for 50% inhibition by displacement of of [125I]NDP-alpha-MSH of human MC5R expressed in CHO cells


Bioorg Med Chem Lett 15: 3430-3 (2005)


Article DOI: 10.1016/j.bmcl.2005.05.012
BindingDB Entry DOI: 10.7270/Q2959H2N
More data for this
Ligand-Target Pair
Melanocortin receptor 4


(Homo sapiens (Human))
BDBM50323156
PNG
(CHEMBL1209458 | N-(2-(4-((3S,4R)-1-tert-butyl-4-(2...)
Show SMILES CC(C)N(CC(N1CCN(CC1)C(=O)[C@@H]1CN(C[C@H]1c1ccc(F)cc1F)C(C)(C)C)C(C)(C)C)S(C)(=O)=O |r|
Show InChI InChI=1S/C29H48F2N4O3S/c1-20(2)35(39(9,37)38)19-26(28(3,4)5)32-12-14-33(15-13-32)27(36)24-18-34(29(6,7)8)17-23(24)22-11-10-21(30)16-25(22)31/h10-11,16,20,23-24,26H,12-15,17-19H2,1-9H3/t23-,24+,26?/m0/s1
PDB

KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 46n/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Displacement of [125I]NDP-alpha-MSH from human MC4 receptor expressed in CHO cells


Bioorg Med Chem Lett 20: 4483-6 (2010)


Article DOI: 10.1016/j.bmcl.2010.06.038
BindingDB Entry DOI: 10.7270/Q2C829GJ
More data for this
Ligand-Target Pair
Melanocortin receptor 4


(Homo sapiens (Human))
BDBM50323156
PNG
(CHEMBL1209458 | N-(2-(4-((3S,4R)-1-tert-butyl-4-(2...)
Show SMILES CC(C)N(CC(N1CCN(CC1)C(=O)[C@@H]1CN(C[C@H]1c1ccc(F)cc1F)C(C)(C)C)C(C)(C)C)S(C)(=O)=O |r|
Show InChI InChI=1S/C29H48F2N4O3S/c1-20(2)35(39(9,37)38)19-26(28(3,4)5)32-12-14-33(15-13-32)27(36)24-18-34(29(6,7)8)17-23(24)22-11-10-21(30)16-25(22)31/h10-11,16,20,23-24,26H,12-15,17-19H2,1-9H3/t23-,24+,26?/m0/s1
PDB

KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 46n/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Agonist activity at human MC4 receptor expressed in CHO cells assessed as increase of alpha-MSH-induced cAMP accumulation


Bioorg Med Chem Lett 20: 4483-6 (2010)


Article DOI: 10.1016/j.bmcl.2010.06.038
BindingDB Entry DOI: 10.7270/Q2C829GJ
More data for this
Ligand-Target Pair
Melanocortin receptor 3


(Homo sapiens (Human))
BDBM50168725
PNG
(1-[2-[((R)-3-Amino-1,2,3,4-tetrahydro-naphthalene-...)
Show SMILES CC(C)(C)NC(=O)C1(CCN(CC1)C(=O)[C@@H](Cc1ccc(Cl)cc1)NC(=O)C1Cc2ccccc2CC1N)C1CCCCC1
Show InChI InChI=1S/C36H49ClN4O3/c1-35(2,3)40-34(44)36(27-11-5-4-6-12-27)17-19-41(20-18-36)33(43)31(21-24-13-15-28(37)16-14-24)39-32(42)29-22-25-9-7-8-10-26(25)23-30(29)38/h7-10,13-16,27,29-31H,4-6,11-12,17-23,38H2,1-3H3,(H,39,42)(H,40,44)/t29?,30?,31-/m1/s1
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 48n/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Concentration required for 50% inhibition by displacement of of [125I]NDP-alpha-MSH of human MC3R expressed in CHO cells


Bioorg Med Chem Lett 15: 3430-3 (2005)


Article DOI: 10.1016/j.bmcl.2005.05.012
BindingDB Entry DOI: 10.7270/Q2959H2N
More data for this
Ligand-Target Pair
Melanocortin receptor 5


(Homo sapiens (Human))
BDBM50024350
PNG
(CHEMBL2113041)
Show SMILES CC(C)(C)NC(=O)C1(CCN(CC1)C(=O)[C@@H](Cc1ccc(Cl)cc1)NC(=O)C1CCCc2ccccc2C1N)C1CCCCC1
Show InChI InChI=1S/C37H51ClN4O3/c1-36(2,3)41-35(45)37(27-12-5-4-6-13-27)20-22-42(23-21-37)34(44)31(24-25-16-18-28(38)19-17-25)40-33(43)30-15-9-11-26-10-7-8-14-29(26)32(30)39/h7-8,10,14,16-19,27,30-32H,4-6,9,11-13,15,20-24,39H2,1-3H3,(H,40,43)(H,41,45)/t30?,31-,32?/m1/s1
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 54n/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Concentration required for 50% inhibition by displacement of of [125I]NDP-alpha-MSH of human MC5R expressed in CHO cells


Bioorg Med Chem Lett 15: 3430-3 (2005)


Article DOI: 10.1016/j.bmcl.2005.05.012
BindingDB Entry DOI: 10.7270/Q2959H2N
More data for this
Ligand-Target Pair
Melanocortin receptor 4


(Homo sapiens (Human))
BDBM50323160
PNG
(CHEMBL1209320 | N-(2-(4-((3S,4R)-1-tert-butyl-4-(2...)
Show SMILES CC(C)N(CC(C1CCCCC1)N1CCN(CC1)C(=O)[C@@H]1CN(C[C@H]1c1ccc(F)cc1F)C(C)(C)C)C(=O)c1cnn(c1)C(C)C |r|
Show InChI InChI=1S/C37H56F2N6O2/c1-25(2)44(35(46)28-20-40-45(21-28)26(3)4)24-34(27-11-9-8-10-12-27)41-15-17-42(18-16-41)36(47)32-23-43(37(5,6)7)22-31(32)30-14-13-29(38)19-33(30)39/h13-14,19-21,25-27,31-32,34H,8-12,15-18,22-24H2,1-7H3/t31-,32+,34?/m0/s1
PDB

KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 62n/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Agonist activity at human MC4 receptor expressed in CHO cells assessed as increase of alpha-MSH-induced cAMP accumulation


Bioorg Med Chem Lett 20: 4483-6 (2010)


Article DOI: 10.1016/j.bmcl.2010.06.038
BindingDB Entry DOI: 10.7270/Q2C829GJ
More data for this
Ligand-Target Pair
Melanocortin receptor 4


(Homo sapiens (Human))
BDBM50323160
PNG
(CHEMBL1209320 | N-(2-(4-((3S,4R)-1-tert-butyl-4-(2...)
Show SMILES CC(C)N(CC(C1CCCCC1)N1CCN(CC1)C(=O)[C@@H]1CN(C[C@H]1c1ccc(F)cc1F)C(C)(C)C)C(=O)c1cnn(c1)C(C)C |r|
Show InChI InChI=1S/C37H56F2N6O2/c1-25(2)44(35(46)28-20-40-45(21-28)26(3)4)24-34(27-11-9-8-10-12-27)41-15-17-42(18-16-41)36(47)32-23-43(37(5,6)7)22-31(32)30-14-13-29(38)19-33(30)39/h13-14,19-21,25-27,31-32,34H,8-12,15-18,22-24H2,1-7H3/t31-,32+,34?/m0/s1
PDB

KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 62n/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Displacement of [125I]NDP-alpha-MSH from human MC4 receptor expressed in CHO cells


Bioorg Med Chem Lett 20: 4483-6 (2010)


Article DOI: 10.1016/j.bmcl.2010.06.038
BindingDB Entry DOI: 10.7270/Q2C829GJ
More data for this
Ligand-Target Pair
Melanocortin receptor 4


(Homo sapiens (Human))
BDBM50323149
PNG
(CHEMBL1209318 | N-(2-(4-((3S,4R)-1-tert-butyl-4-(2...)
Show SMILES CC(C)N(CC(C1CCCCC1)N1CCN(CC1)C(=O)[C@@H]1CN(C[C@H]1c1ccc(F)cc1F)C(C)(C)C)C(=O)c1cccnn1 |r|
Show InChI InChI=1S/C35H50F2N6O2/c1-24(2)43(34(45)31-12-9-15-38-39-31)23-32(25-10-7-6-8-11-25)40-16-18-41(19-17-40)33(44)29-22-42(35(3,4)5)21-28(29)27-14-13-26(36)20-30(27)37/h9,12-15,20,24-25,28-29,32H,6-8,10-11,16-19,21-23H2,1-5H3/t28-,29+,32?/m0/s1
PDB

KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 64n/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Displacement of [125I]NDP-alpha-MSH from human MC4 receptor expressed in CHO cells


Bioorg Med Chem Lett 20: 4483-6 (2010)


Article DOI: 10.1016/j.bmcl.2010.06.038
BindingDB Entry DOI: 10.7270/Q2C829GJ
More data for this
Ligand-Target Pair
Melanocortin receptor 4


(Homo sapiens (Human))
BDBM50323149
PNG
(CHEMBL1209318 | N-(2-(4-((3S,4R)-1-tert-butyl-4-(2...)
Show SMILES CC(C)N(CC(C1CCCCC1)N1CCN(CC1)C(=O)[C@@H]1CN(C[C@H]1c1ccc(F)cc1F)C(C)(C)C)C(=O)c1cccnn1 |r|
Show InChI InChI=1S/C35H50F2N6O2/c1-24(2)43(34(45)31-12-9-15-38-39-31)23-32(25-10-7-6-8-11-25)40-16-18-41(19-17-40)33(44)29-22-42(35(3,4)5)21-28(29)27-14-13-26(36)20-30(27)37/h9,12-15,20,24-25,28-29,32H,6-8,10-11,16-19,21-23H2,1-5H3/t28-,29+,32?/m0/s1
PDB

KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 64n/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Agonist activity at human MC4 receptor expressed in CHO cells assessed as increase of alpha-MSH-induced cAMP accumulation


Bioorg Med Chem Lett 20: 4483-6 (2010)


Article DOI: 10.1016/j.bmcl.2010.06.038
BindingDB Entry DOI: 10.7270/Q2C829GJ
More data for this
Ligand-Target Pair
Melanocortin receptor 5


(Homo sapiens (Human))
BDBM50168724
PNG
(1-[(R)-2-[((1S,2S)-1-Amino-1,2,3,4-tetrahydro-naph...)
Show SMILES CC(C)(C)NC(=O)C1(CCN(CC1)C(=O)[C@@H](Cc1ccc(Cl)cc1)NC(=O)[C@H]1CCc2ccccc2[C@H]1N)C1CCCCC1
Show InChI InChI=1S/C36H49ClN4O3/c1-35(2,3)40-34(44)36(26-10-5-4-6-11-26)19-21-41(22-20-36)33(43)30(23-24-13-16-27(37)17-14-24)39-32(42)29-18-15-25-9-7-8-12-28(25)31(29)38/h7-9,12-14,16-17,26,29-31H,4-6,10-11,15,18-23,38H2,1-3H3,(H,39,42)(H,40,44)/t29-,30+,31+/m0/s1
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 64n/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Concentration required for 50% inhibition by displacement of of [125I]NDP-alpha-MSH of human MC5R expressed in CHO cells


Bioorg Med Chem Lett 15: 3430-3 (2005)


Article DOI: 10.1016/j.bmcl.2005.05.012
BindingDB Entry DOI: 10.7270/Q2959H2N
More data for this
Ligand-Target Pair
Melanocortin receptor 3


(Homo sapiens (Human))
BDBM50168723
PNG
(1-[2-[((R)-1-Amino-indane-2-carbonyl)-amino]-3-(4-...)
Show SMILES CC(C)(C)NC(=O)C1(CCN(CC1)C(=O)[C@@H](Cc1ccc(Cl)cc1)NC(=O)C1Cc2ccccc2C1N)C1CCCCC1
Show InChI InChI=1S/C35H47ClN4O3/c1-34(2,3)39-33(43)35(25-10-5-4-6-11-25)17-19-40(20-18-35)32(42)29(21-23-13-15-26(36)16-14-23)38-31(41)28-22-24-9-7-8-12-27(24)30(28)37/h7-9,12-16,25,28-30H,4-6,10-11,17-22,37H2,1-3H3,(H,38,41)(H,39,43)/t28?,29-,30?/m1/s1
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 83n/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Concentration required for 50% inhibition by displacement of of [125I]NDP-alpha-MSH of human MC3R expressed in CHO cells


Bioorg Med Chem Lett 15: 3430-3 (2005)


Article DOI: 10.1016/j.bmcl.2005.05.012
BindingDB Entry DOI: 10.7270/Q2959H2N
More data for this
Ligand-Target Pair
Melanocortin receptor 3


(Homo sapiens (Human))
BDBM50024350
PNG
(CHEMBL2113041)
Show SMILES CC(C)(C)NC(=O)C1(CCN(CC1)C(=O)[C@@H](Cc1ccc(Cl)cc1)NC(=O)C1CCCc2ccccc2C1N)C1CCCCC1
Show InChI InChI=1S/C37H51ClN4O3/c1-36(2,3)41-35(45)37(27-12-5-4-6-13-27)20-22-42(23-21-37)34(44)31(24-25-16-18-28(38)19-17-25)40-33(43)30-15-9-11-26-10-7-8-14-29(26)32(30)39/h7-8,10,14,16-19,27,30-32H,4-6,9,11-13,15,20-24,39H2,1-3H3,(H,40,43)(H,41,45)/t30?,31-,32?/m1/s1
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 97n/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Concentration required for 50% inhibition by displacement of of [125I]NDP-alpha-MSH of human MC3R expressed in CHO cells


Bioorg Med Chem Lett 15: 3430-3 (2005)


Article DOI: 10.1016/j.bmcl.2005.05.012
BindingDB Entry DOI: 10.7270/Q2959H2N
More data for this
Ligand-Target Pair
Melanocortin receptor 3


(Homo sapiens (Human))
BDBM50168724
PNG
(1-[(R)-2-[((1S,2S)-1-Amino-1,2,3,4-tetrahydro-naph...)
Show SMILES CC(C)(C)NC(=O)C1(CCN(CC1)C(=O)[C@@H](Cc1ccc(Cl)cc1)NC(=O)[C@H]1CCc2ccccc2[C@H]1N)C1CCCCC1
Show InChI InChI=1S/C36H49ClN4O3/c1-35(2,3)40-34(44)36(26-10-5-4-6-11-26)19-21-41(22-20-36)33(43)30(23-24-13-16-27(37)17-14-24)39-32(42)29-18-15-25-9-7-8-12-28(25)31(29)38/h7-9,12-14,16-17,26,29-31H,4-6,10-11,15,18-23,38H2,1-3H3,(H,39,42)(H,40,44)/t29-,30+,31+/m0/s1
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 120n/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Concentration required for 50% inhibition by displacement of of [125I]NDP-alpha-MSH of human MC3R expressed in CHO cells


Bioorg Med Chem Lett 15: 3430-3 (2005)


Article DOI: 10.1016/j.bmcl.2005.05.012
BindingDB Entry DOI: 10.7270/Q2959H2N
More data for this
Ligand-Target Pair
Melanocortin receptor 4


(Homo sapiens (Human))
BDBM50323148
PNG
(CHEMBL1209319 | N-(2-(4-((3S,4R)-1-tert-butyl-4-(2...)
Show SMILES CC(C)N(CC(C1CCCCC1)N1CCN(CC1)C(=O)[C@@H]1CN(C[C@H]1c1ccc(F)cc1F)C(C)(C)C)C(=O)c1ncccn1 |r|
Show InChI InChI=1S/C35H50F2N6O2/c1-24(2)43(34(45)32-38-14-9-15-39-32)23-31(25-10-7-6-8-11-25)40-16-18-41(19-17-40)33(44)29-22-42(35(3,4)5)21-28(29)27-13-12-26(36)20-30(27)37/h9,12-15,20,24-25,28-29,31H,6-8,10-11,16-19,21-23H2,1-5H3/t28-,29+,31?/m0/s1
PDB

KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 130n/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Displacement of [125I]NDP-alpha-MSH from human MC4 receptor expressed in CHO cells


Bioorg Med Chem Lett 20: 4483-6 (2010)


Article DOI: 10.1016/j.bmcl.2010.06.038
BindingDB Entry DOI: 10.7270/Q2C829GJ
More data for this
Ligand-Target Pair
Melanocortin receptor 5


(Homo sapiens (Human))
BDBM50323149
PNG
(CHEMBL1209318 | N-(2-(4-((3S,4R)-1-tert-butyl-4-(2...)
Show SMILES CC(C)N(CC(C1CCCCC1)N1CCN(CC1)C(=O)[C@@H]1CN(C[C@H]1c1ccc(F)cc1F)C(C)(C)C)C(=O)c1cccnn1 |r|
Show InChI InChI=1S/C35H50F2N6O2/c1-24(2)43(34(45)31-12-9-15-38-39-31)23-32(25-10-7-6-8-11-25)40-16-18-41(19-17-40)33(44)29-22-42(35(3,4)5)21-28(29)27-14-13-26(36)20-30(27)37/h9,12-15,20,24-25,28-29,32H,6-8,10-11,16-19,21-23H2,1-5H3/t28-,29+,32?/m0/s1
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 130n/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Displacement of [125I]NDP-alpha-MSH from human MC5 receptor expressed in CHO cells


Bioorg Med Chem Lett 20: 4483-6 (2010)


Article DOI: 10.1016/j.bmcl.2010.06.038
BindingDB Entry DOI: 10.7270/Q2C829GJ
More data for this
Ligand-Target Pair
Melanocortin receptor 4


(Homo sapiens (Human))
BDBM50323157
PNG
(CHEMBL1209383 | N-(2-(4-((3S,4R)-1-tert-butyl-4-(2...)
Show SMILES CC(C)N(CC(N1CCN(CC1)C(=O)[C@@H]1CN(C[C@H]1c1ccc(F)cc1F)C(C)(C)C)C(C)(C)C)C(C)=O |r|
Show InChI InChI=1S/C30H48F2N4O2/c1-20(2)36(21(3)37)19-27(29(4,5)6)33-12-14-34(15-13-33)28(38)25-18-35(30(7,8)9)17-24(25)23-11-10-22(31)16-26(23)32/h10-11,16,20,24-25,27H,12-15,17-19H2,1-9H3/t24-,25+,27?/m0/s1
PDB

KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 150n/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Displacement of [125I]NDP-alpha-MSH from human MC4 receptor expressed in CHO cells


Bioorg Med Chem Lett 20: 4483-6 (2010)


Article DOI: 10.1016/j.bmcl.2010.06.038
BindingDB Entry DOI: 10.7270/Q2C829GJ
More data for this
Ligand-Target Pair
Melanocortin receptor 4


(Homo sapiens (Human))
BDBM50323157
PNG
(CHEMBL1209383 | N-(2-(4-((3S,4R)-1-tert-butyl-4-(2...)
Show SMILES CC(C)N(CC(N1CCN(CC1)C(=O)[C@@H]1CN(C[C@H]1c1ccc(F)cc1F)C(C)(C)C)C(C)(C)C)C(C)=O |r|
Show InChI InChI=1S/C30H48F2N4O2/c1-20(2)36(21(3)37)19-27(29(4,5)6)33-12-14-34(15-13-33)28(38)25-18-35(30(7,8)9)17-24(25)23-11-10-22(31)16-26(23)32/h10-11,16,20,24-25,27H,12-15,17-19H2,1-9H3/t24-,25+,27?/m0/s1
PDB

KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 150n/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Agonist activity at human MC4 receptor expressed in CHO cells assessed as increase of alpha-MSH-induced cAMP accumulation


Bioorg Med Chem Lett 20: 4483-6 (2010)


Article DOI: 10.1016/j.bmcl.2010.06.038
BindingDB Entry DOI: 10.7270/Q2C829GJ
More data for this
Ligand-Target Pair
Melanocortin receptor 3


(Homo sapiens (Human))
BDBM50168727
PNG
(1-[(R)-2-[((1S,2S)-1-Amino-1-methyl-1,2,3,4-tetrah...)
Show SMILES CC(C)(C)NC(=O)C1(CCN(CC1)C(=O)[C@@H](Cc1ccc(Cl)cc1)NC(=O)[C@H]1CCc2ccccc2[C@@]1(C)N)C1CCCCC1
Show InChI InChI=1S/C37H51ClN4O3/c1-35(2,3)41-34(45)37(27-11-6-5-7-12-27)20-22-42(23-21-37)33(44)31(24-25-14-17-28(38)18-15-25)40-32(43)30-19-16-26-10-8-9-13-29(26)36(30,4)39/h8-10,13-15,17-18,27,30-31H,5-7,11-12,16,19-24,39H2,1-4H3,(H,40,43)(H,41,45)/t30-,31-,36-/m1/s1
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 170n/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Concentration required for 50% inhibition by displacement of of [125I]NDP-alpha-MSH of human MC3R expressed in CHO cells


Bioorg Med Chem Lett 15: 3430-3 (2005)


Article DOI: 10.1016/j.bmcl.2005.05.012
BindingDB Entry DOI: 10.7270/Q2959H2N
More data for this
Ligand-Target Pair
Melanocortin receptor 4


(Homo sapiens (Human))
BDBM50323153
PNG
(((3S,4R)-1-tert-butyl-4-(2,4-difluorophenyl)pyrrol...)
Show SMILES CCCN(CCC)CC(C1CCCCC1)N1CCN(CC1)C(=O)[C@@H]1CN(C[C@H]1c1ccc(F)cc1F)C(C)(C)C |r|
Show InChI InChI=1S/C33H54F2N4O/c1-6-15-36(16-7-2)24-31(25-11-9-8-10-12-25)37-17-19-38(20-18-37)32(40)29-23-39(33(3,4)5)22-28(29)27-14-13-26(34)21-30(27)35/h13-14,21,25,28-29,31H,6-12,15-20,22-24H2,1-5H3/t28-,29+,31?/m0/s1
PDB

KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 200n/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Displacement of [125I]NDP-alpha-MSH from human MC4 receptor expressed in CHO cells


Bioorg Med Chem Lett 20: 4483-6 (2010)


Article DOI: 10.1016/j.bmcl.2010.06.038
BindingDB Entry DOI: 10.7270/Q2C829GJ
More data for this
Ligand-Target Pair
Melanocyte-stimulating hormone receptor


(Homo sapiens (Human))
BDBM50024350
PNG
(CHEMBL2113041)
Show SMILES CC(C)(C)NC(=O)C1(CCN(CC1)C(=O)[C@@H](Cc1ccc(Cl)cc1)NC(=O)C1CCCc2ccccc2C1N)C1CCCCC1
Show InChI InChI=1S/C37H51ClN4O3/c1-36(2,3)41-35(45)37(27-12-5-4-6-13-27)20-22-42(23-21-37)34(44)31(24-25-16-18-28(38)19-17-25)40-33(43)30-15-9-11-26-10-7-8-14-29(26)32(30)39/h7-8,10,14,16-19,27,30-32H,4-6,9,11-13,15,20-24,39H2,1-3H3,(H,40,43)(H,41,45)/t30?,31-,32?/m1/s1
PDB

KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 220n/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Concentration required for 50% inhibition by displacement of of [125I]NDP-alpha-MSH of human MC1R expressed in CHO cells


Bioorg Med Chem Lett 15: 3430-3 (2005)


Article DOI: 10.1016/j.bmcl.2005.05.012
BindingDB Entry DOI: 10.7270/Q2959H2N
More data for this
Ligand-Target Pair
Melanocortin receptor 5


(Homo sapiens (Human))
BDBM50323150
PNG
(CHEMBL1209253 | N-(2-(4-((3S,4R)-1-tert-butyl-4-(2...)
Show SMILES CC(C)N(CC(C1CCCCC1)N1CCN(CC1)C(=O)[C@@H]1CN(C[C@H]1c1ccc(F)cc1F)C(C)(C)C)S(C)(=O)=O |r|
Show InChI InChI=1S/C31H50F2N4O3S/c1-22(2)37(41(6,39)40)21-29(23-10-8-7-9-11-23)34-14-16-35(17-15-34)30(38)27-20-36(31(3,4)5)19-26(27)25-13-12-24(32)18-28(25)33/h12-13,18,22-23,26-27,29H,7-11,14-17,19-21H2,1-6H3/t26-,27+,29?/m0/s1
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 250n/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Displacement of [125I]NDP-alpha-MSH from human MC5 receptor expressed in CHO cells


Bioorg Med Chem Lett 20: 4483-6 (2010)


Article DOI: 10.1016/j.bmcl.2010.06.038
BindingDB Entry DOI: 10.7270/Q2C829GJ
More data for this
Ligand-Target Pair
Melanocortin receptor 4


(Homo sapiens (Human))
BDBM50323152
PNG
(((3S,4R)-1-tert-butyl-4-(2,4-difluorophenyl)pyrrol...)
Show SMILES CCN(CC)CC(C1CCCCC1)N1CCN(CC1)C(=O)[C@@H]1CN(C[C@H]1c1ccc(F)cc1F)C(C)(C)C |r|
Show InChI InChI=1S/C31H50F2N4O/c1-6-34(7-2)22-29(23-11-9-8-10-12-23)35-15-17-36(18-16-35)30(38)27-21-37(31(3,4)5)20-26(27)25-14-13-24(32)19-28(25)33/h13-14,19,23,26-27,29H,6-12,15-18,20-22H2,1-5H3/t26-,27+,29?/m0/s1
PDB

KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 260n/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Agonist activity at human MC4 receptor expressed in CHO cells assessed as increase of alpha-MSH-induced cAMP accumulation


Bioorg Med Chem Lett 20: 4483-6 (2010)


Article DOI: 10.1016/j.bmcl.2010.06.038
BindingDB Entry DOI: 10.7270/Q2C829GJ
More data for this
Ligand-Target Pair
Melanocortin receptor 4


(Homo sapiens (Human))
BDBM50323155
PNG
(((3S,4R)-1-tert-butyl-4-(2,4-difluorophenyl)pyrrol...)
Show SMILES CC(C)NCC(C1CCCCC1)N1CCN(CC1)C(=O)[C@@H]1CN(C[C@H]1c1ccc(F)cc1F)C(C)(C)C |r|
Show InChI InChI=1S/C30H48F2N4O/c1-21(2)33-18-28(22-9-7-6-8-10-22)34-13-15-35(16-14-34)29(37)26-20-36(30(3,4)5)19-25(26)24-12-11-23(31)17-27(24)32/h11-12,17,21-22,25-26,28,33H,6-10,13-16,18-20H2,1-5H3/t25-,26+,28?/m0/s1
PDB

KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 310n/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Agonist activity at human MC4 receptor expressed in CHO cells assessed as increase of alpha-MSH-induced cAMP accumulation


Bioorg Med Chem Lett 20: 4483-6 (2010)


Article DOI: 10.1016/j.bmcl.2010.06.038
BindingDB Entry DOI: 10.7270/Q2C829GJ
More data for this
Ligand-Target Pair
Melanocortin receptor 5


(Homo sapiens (Human))
BDBM50119368
PNG
((R)-1,2,3,4-Tetrahydro-isoquinoline-3-carboxylic a...)
Show SMILES Clc1ccc(C[C@@H](NC(=O)[C@H]2Cc3ccccc3CN2)C(=O)N2CCC(Cn3cncn3)(CC2)C2CCCCC2)cc1
Show InChI InChI=1S/C33H41ClN6O2/c34-28-12-10-24(11-13-28)18-30(38-31(41)29-19-25-6-4-5-7-26(25)20-36-29)32(42)39-16-14-33(15-17-39,21-40-23-35-22-37-40)27-8-2-1-3-9-27/h4-7,10-13,22-23,27,29-30,36H,1-3,8-9,14-21H2,(H,38,41)/t29-,30-/m1/s1
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
Purchase

CHEMBL
MCE
PC cid
PC sid
PDB
UniChem

Patents


Similars

Article
PubMed
n/an/a 326n/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Concentration required for 50% inhibition by displacement of of [125I]NDP-alpha-MSH of human MC5R expressed in CHO cells


Bioorg Med Chem Lett 15: 3430-3 (2005)


Article DOI: 10.1016/j.bmcl.2005.05.012
BindingDB Entry DOI: 10.7270/Q2959H2N
More data for this
Ligand-Target Pair
Melanocyte-stimulating hormone receptor


(Homo sapiens (Human))
BDBM50168724
PNG
(1-[(R)-2-[((1S,2S)-1-Amino-1,2,3,4-tetrahydro-naph...)
Show SMILES CC(C)(C)NC(=O)C1(CCN(CC1)C(=O)[C@@H](Cc1ccc(Cl)cc1)NC(=O)[C@H]1CCc2ccccc2[C@H]1N)C1CCCCC1
Show InChI InChI=1S/C36H49ClN4O3/c1-35(2,3)40-34(44)36(26-10-5-4-6-11-26)19-21-41(22-20-36)33(43)30(23-24-13-16-27(37)17-14-24)39-32(42)29-18-15-25-9-7-8-12-28(25)31(29)38/h7-9,12-14,16-17,26,29-31H,4-6,10-11,15,18-23,38H2,1-3H3,(H,39,42)(H,40,44)/t29-,30+,31+/m0/s1
PDB

KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 530n/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Concentration required for 50% inhibition by displacement of of [125I]NDP-alpha-MSH of human MC1R expressed in CHO cells


Bioorg Med Chem Lett 15: 3430-3 (2005)


Article DOI: 10.1016/j.bmcl.2005.05.012
BindingDB Entry DOI: 10.7270/Q2959H2N
More data for this
Ligand-Target Pair
Melanocyte-stimulating hormone receptor


(Homo sapiens (Human))
BDBM50168727
PNG
(1-[(R)-2-[((1S,2S)-1-Amino-1-methyl-1,2,3,4-tetrah...)
Show SMILES CC(C)(C)NC(=O)C1(CCN(CC1)C(=O)[C@@H](Cc1ccc(Cl)cc1)NC(=O)[C@H]1CCc2ccccc2[C@@]1(C)N)C1CCCCC1
Show InChI InChI=1S/C37H51ClN4O3/c1-35(2,3)41-34(45)37(27-11-6-5-7-12-27)20-22-42(23-21-37)33(44)31(24-25-14-17-28(38)18-15-25)40-32(43)30-19-16-26-10-8-9-13-29(26)36(30,4)39/h8-10,13-15,17-18,27,30-31H,5-7,11-12,16,19-24,39H2,1-4H3,(H,40,43)(H,41,45)/t30-,31-,36-/m1/s1
PDB

KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 620n/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Concentration required for 50% inhibition by displacement of of [125I]NDP-alpha-MSH of human MC1R expressed in CHO cells


Bioorg Med Chem Lett 15: 3430-3 (2005)


Article DOI: 10.1016/j.bmcl.2005.05.012
BindingDB Entry DOI: 10.7270/Q2959H2N
More data for this
Ligand-Target Pair
Melanocortin receptor 5


(Homo sapiens (Human))
BDBM50323160
PNG
(CHEMBL1209320 | N-(2-(4-((3S,4R)-1-tert-butyl-4-(2...)
Show SMILES CC(C)N(CC(C1CCCCC1)N1CCN(CC1)C(=O)[C@@H]1CN(C[C@H]1c1ccc(F)cc1F)C(C)(C)C)C(=O)c1cnn(c1)C(C)C |r|
Show InChI InChI=1S/C37H56F2N6O2/c1-25(2)44(35(46)28-20-40-45(21-28)26(3)4)24-34(27-11-9-8-10-12-27)41-15-17-42(18-16-41)36(47)32-23-43(37(5,6)7)22-31(32)30-14-13-29(38)19-33(30)39/h13-14,19-21,25-27,31-32,34H,8-12,15-18,22-24H2,1-7H3/t31-,32+,34?/m0/s1
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 620n/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Displacement of [125I]NDP-alpha-MSH from human MC5 receptor expressed in CHO cells


Bioorg Med Chem Lett 20: 4483-6 (2010)


Article DOI: 10.1016/j.bmcl.2010.06.038
BindingDB Entry DOI: 10.7270/Q2C829GJ
More data for this
Ligand-Target Pair
Melanocortin receptor 5


(Homo sapiens (Human))
BDBM50323151
PNG
(CHEMBL1209252 | N-(2-(4-((3S,4R)-1-tert-butyl-4-(2...)
Show SMILES CC(C)N(CC(C1CCCCC1)N1CCN(CC1)C(=O)[C@@H]1CN(C[C@H]1c1ccc(F)cc1F)C(C)(C)C)C(C)=O |r|
Show InChI InChI=1S/C32H50F2N4O2/c1-22(2)38(23(3)39)21-30(24-10-8-7-9-11-24)35-14-16-36(17-15-35)31(40)28-20-37(32(4,5)6)19-27(28)26-13-12-25(33)18-29(26)34/h12-13,18,22,24,27-28,30H,7-11,14-17,19-21H2,1-6H3/t27-,28+,30?/m0/s1
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 660n/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Displacement of [125I]NDP-alpha-MSH from human MC5 receptor expressed in CHO cells


Bioorg Med Chem Lett 20: 4483-6 (2010)


Article DOI: 10.1016/j.bmcl.2010.06.038
BindingDB Entry DOI: 10.7270/Q2C829GJ
More data for this
Ligand-Target Pair
Melanocyte-stimulating hormone receptor


(Homo sapiens (Human))
BDBM50323160
PNG
(CHEMBL1209320 | N-(2-(4-((3S,4R)-1-tert-butyl-4-(2...)
Show SMILES CC(C)N(CC(C1CCCCC1)N1CCN(CC1)C(=O)[C@@H]1CN(C[C@H]1c1ccc(F)cc1F)C(C)(C)C)C(=O)c1cnn(c1)C(C)C |r|
Show InChI InChI=1S/C37H56F2N6O2/c1-25(2)44(35(46)28-20-40-45(21-28)26(3)4)24-34(27-11-9-8-10-12-27)41-15-17-42(18-16-41)36(47)32-23-43(37(5,6)7)22-31(32)30-14-13-29(38)19-33(30)39/h13-14,19-21,25-27,31-32,34H,8-12,15-18,22-24H2,1-7H3/t31-,32+,34?/m0/s1
PDB

KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 730n/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Displacement of [125I]NDP-alpha-MSH from human MC1 receptor expressed in CHO cells


Bioorg Med Chem Lett 20: 4483-6 (2010)


Article DOI: 10.1016/j.bmcl.2010.06.038
BindingDB Entry DOI: 10.7270/Q2C829GJ
More data for this
Ligand-Target Pair
Melanocortin receptor 3


(Homo sapiens (Human))
BDBM50119368
PNG
((R)-1,2,3,4-Tetrahydro-isoquinoline-3-carboxylic a...)
Show SMILES Clc1ccc(C[C@@H](NC(=O)[C@H]2Cc3ccccc3CN2)C(=O)N2CCC(Cn3cncn3)(CC2)C2CCCCC2)cc1
Show InChI InChI=1S/C33H41ClN6O2/c34-28-12-10-24(11-13-28)18-30(38-31(41)29-19-25-6-4-5-7-26(25)20-36-29)32(42)39-16-14-33(15-17-39,21-40-23-35-22-37-40)27-8-2-1-3-9-27/h4-7,10-13,22-23,27,29-30,36H,1-3,8-9,14-21H2,(H,38,41)/t29-,30-/m1/s1
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
Purchase

CHEMBL
MCE
PC cid
PC sid
PDB
UniChem

Patents


Similars

Article
PubMed
n/an/a 761n/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Concentration required for 50% inhibition by displacement of of [125I]NDP-alpha-MSH of human MC3R expressed in CHO cells


Bioorg Med Chem Lett 15: 3430-3 (2005)


Article DOI: 10.1016/j.bmcl.2005.05.012
BindingDB Entry DOI: 10.7270/Q2959H2N
More data for this
Ligand-Target Pair
Melanocortin receptor 3


(Homo sapiens (Human))
BDBM50323149
PNG
(CHEMBL1209318 | N-(2-(4-((3S,4R)-1-tert-butyl-4-(2...)
Show SMILES CC(C)N(CC(C1CCCCC1)N1CCN(CC1)C(=O)[C@@H]1CN(C[C@H]1c1ccc(F)cc1F)C(C)(C)C)C(=O)c1cccnn1 |r|
Show InChI InChI=1S/C35H50F2N6O2/c1-24(2)43(34(45)31-12-9-15-38-39-31)23-32(25-10-7-6-8-11-25)40-16-18-41(19-17-40)33(44)29-22-42(35(3,4)5)21-28(29)27-14-13-26(36)20-30(27)37/h9,12-15,20,24-25,28-29,32H,6-8,10-11,16-19,21-23H2,1-5H3/t28-,29+,32?/m0/s1
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 770n/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Displacement of [125I]NDP-alpha-MSH from human MC3 receptor expressed in CHO cells


Bioorg Med Chem Lett 20: 4483-6 (2010)


Article DOI: 10.1016/j.bmcl.2010.06.038
BindingDB Entry DOI: 10.7270/Q2C829GJ
More data for this
Ligand-Target Pair
Displayed 1 to 50 (of 99 total )  |  Next  |  Last  >>
Jump to: