Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Genome polyprotein (Hepatitis C virus) | BDBM50142916 ((1S,4R,6S,14S,18R)-14-Cyclopentyloxycarbonylamino-...) | PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 0.800 | n/a | n/a | n/a | n/a | n/a | n/a |
IDENIX Pharmaceuticals Curated by ChEMBL | Assay Description Inhibition of full length Hepatitis C virus genotype 1b Con1 NS3/4A by FRET assay | Bioorg Med Chem Lett 24: 4444-9 (2014) Article DOI: 10.1016/j.bmcl.2014.08.002 BindingDB Entry DOI: 10.7270/Q20C4XBK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Genome polyprotein (Hepatitis C virus) | BDBM50023510 (CHEMBL3326826) | PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.30 | n/a | n/a | n/a | n/a | n/a | n/a |
IDENIX Pharmaceuticals Curated by ChEMBL | Assay Description Inhibition of full length Hepatitis C virus genotype 1b Con1 NS3/4A by FRET assay | Bioorg Med Chem Lett 24: 4444-9 (2014) Article DOI: 10.1016/j.bmcl.2014.08.002 BindingDB Entry DOI: 10.7270/Q20C4XBK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 2B (Homo sapiens (Human)) | BDBM50191171 (2-(4-flurophenyl)-1,10b-dihydro-benzo[e]pyrazolo[1...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.80 | n/a | n/a | n/a | n/a | n/a | n/a |
Hopital Saint-Louis Curated by ChEMBL | Assay Description Activity at 5HT2B receptor expressed in CHO cell assessed as inhibition of alpha-methyl-5HT-stimulated calcium release | Bioorg Med Chem Lett 16: 4830-3 (2006) Article DOI: 10.1016/j.bmcl.2006.06.068 BindingDB Entry DOI: 10.7270/Q2BV7G7X | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Genome polyprotein (Hepatitis C virus) | BDBM50023579 (CHEMBL3326830) | PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 2.10 | n/a | n/a | n/a | n/a | n/a | n/a |
IDENIX Pharmaceuticals Curated by ChEMBL | Assay Description Inhibition of full length Hepatitis C virus genotype 1b Con1 NS3/4A by FRET assay | Bioorg Med Chem Lett 24: 4444-9 (2014) Article DOI: 10.1016/j.bmcl.2014.08.002 BindingDB Entry DOI: 10.7270/Q20C4XBK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Genome polyprotein (Hepatitis C virus) | BDBM50023508 (CHEMBL3326539) | PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 3.5 | n/a | n/a | n/a | n/a | n/a | n/a |
IDENIX Pharmaceuticals Curated by ChEMBL | Assay Description Inhibition of full length Hepatitis C virus genotype 1b Con1 NS3/4A by FRET assay | Bioorg Med Chem Lett 24: 4444-9 (2014) Article DOI: 10.1016/j.bmcl.2014.08.002 BindingDB Entry DOI: 10.7270/Q20C4XBK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Genome polyprotein (Hepatitis C virus) | BDBM50023578 (CHEMBL3326829) | PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 6.60 | n/a | n/a | n/a | n/a | n/a | n/a |
IDENIX Pharmaceuticals Curated by ChEMBL | Assay Description Inhibition of full length Hepatitis C virus genotype 1b Con1 NS3/4A by FRET assay | Bioorg Med Chem Lett 24: 4444-9 (2014) Article DOI: 10.1016/j.bmcl.2014.08.002 BindingDB Entry DOI: 10.7270/Q20C4XBK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 2B (Homo sapiens (Human)) | BDBM50191182 (1-propyl-4'-(pyridin-4-yl)-8'-oxa-5',6'-diazaspiro...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 15 | n/a | n/a | n/a | n/a | n/a | n/a |
Hopital Saint-Louis Curated by ChEMBL | Assay Description Activity at 5HT2B receptor expressed in CHO cell assessed as inhibition of alpha-methyl-5HT-stimulated calcium release | Bioorg Med Chem Lett 16: 4830-3 (2006) Article DOI: 10.1016/j.bmcl.2006.06.068 BindingDB Entry DOI: 10.7270/Q2BV7G7X | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Reverse transcriptase (Human immunodeficiency virus 1) | BDBM50138406 (3TC Triphosphate | CHEMBL1230 | LAMIVUDINE | Lamiv...) | PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | Purchase CHEMBL KEGG PC cid PC sid PDB UniChem Similars | Article PubMed | n/a | n/a | 15 | n/a | n/a | n/a | n/a | n/a | n/a |
Idenix an MSD Company Curated by ChEMBL | Assay Description Inhibition of full-length wild-type HIV1 reverse transcriptase expressed in Escherichia coli BL21(DE3) pre-incubated for 30 mins before addition of t... | J Med Chem 61: 9218-9228 (2018) Article DOI: 10.1021/acs.jmedchem.8b00141 BindingDB Entry DOI: 10.7270/Q2NC63TK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 2B (Homo sapiens (Human)) | BDBM50191179 (1-(2-phenylethyl)-4'-(pyridin-4-yl)-8'-oxa-5',6'-d...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 16 | n/a | n/a | n/a | n/a | n/a | n/a |
Hopital Saint-Louis Curated by ChEMBL | Assay Description Activity at 5HT2B receptor expressed in CHO cell assessed as inhibition of alpha-methyl-5HT-stimulated calcium release | Bioorg Med Chem Lett 16: 4830-3 (2006) Article DOI: 10.1016/j.bmcl.2006.06.068 BindingDB Entry DOI: 10.7270/Q2BV7G7X | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Genome polyprotein (Hepatitis C virus) | BDBM50023509 (CHEMBL3326540) | PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 17 | n/a | n/a | n/a | n/a | n/a | n/a |
IDENIX Pharmaceuticals Curated by ChEMBL | Assay Description Inhibition of full length Hepatitis C virus genotype 1b Con1 NS3/4A by FRET assay | Bioorg Med Chem Lett 24: 4444-9 (2014) Article DOI: 10.1016/j.bmcl.2014.08.002 BindingDB Entry DOI: 10.7270/Q20C4XBK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 2B (Homo sapiens (Human)) | BDBM50191173 (1-(2-methylpropyl)-4'-(pyridin-4-yl)-8'-oxa-5',6'-...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 21 | n/a | n/a | n/a | n/a | n/a | n/a |
Hopital Saint-Louis Curated by ChEMBL | Assay Description Activity at 5HT2B receptor expressed in CHO cell assessed as inhibition of alpha-methyl-5HT-stimulated calcium release | Bioorg Med Chem Lett 16: 4830-3 (2006) Article DOI: 10.1016/j.bmcl.2006.06.068 BindingDB Entry DOI: 10.7270/Q2BV7G7X | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 2B (Homo sapiens (Human)) | BDBM50191181 (12'-fluoro-4'-(4-fluorophenyl)-1-propyl-8'-oxa-5',...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 26 | n/a | n/a | n/a | n/a | n/a | n/a |
Hopital Saint-Louis Curated by ChEMBL | Assay Description Activity at 5HT2B receptor expressed in CHO cell assessed as inhibition of alpha-methyl-5HT-stimulated calcium release | Bioorg Med Chem Lett 16: 4830-3 (2006) Article DOI: 10.1016/j.bmcl.2006.06.068 BindingDB Entry DOI: 10.7270/Q2BV7G7X | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 2B (Homo sapiens (Human)) | BDBM50191208 (12'-bromo-4'-(4-fluorophenyl)-1-propyl-8'-oxa-5',6...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 29 | n/a | n/a | n/a | n/a | n/a | n/a |
Hopital Saint-Louis Curated by ChEMBL | Assay Description Activity at 5HT2B receptor expressed in CHO cell assessed as inhibition of alpha-methyl-5HT-stimulated calcium release | Bioorg Med Chem Lett 16: 4830-3 (2006) Article DOI: 10.1016/j.bmcl.2006.06.068 BindingDB Entry DOI: 10.7270/Q2BV7G7X | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 2B (Homo sapiens (Human)) | BDBM50191194 (12'-bromo-4'-(4-fluorophenyl)-1-methyl-8'-oxa-5',6...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 30 | n/a | n/a | n/a | n/a | n/a | n/a |
Hopital Saint-Louis Curated by ChEMBL | Assay Description Activity at 5HT2B receptor expressed in CHO cell assessed as inhibition of alpha-methyl-5HT-stimulated calcium release | Bioorg Med Chem Lett 16: 4830-3 (2006) Article DOI: 10.1016/j.bmcl.2006.06.068 BindingDB Entry DOI: 10.7270/Q2BV7G7X | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 2B (Homo sapiens (Human)) | BDBM50191191 (12'-chloro-4'-(4-fluorophenyl)-1-propyl-8'-oxa-5',...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 32 | n/a | n/a | n/a | n/a | n/a | n/a |
Hopital Saint-Louis Curated by ChEMBL | Assay Description Activity at 5HT2B receptor expressed in CHO cell assessed as inhibition of alpha-methyl-5HT-stimulated calcium release | Bioorg Med Chem Lett 16: 4830-3 (2006) Article DOI: 10.1016/j.bmcl.2006.06.068 BindingDB Entry DOI: 10.7270/Q2BV7G7X | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 2B (Homo sapiens (Human)) | BDBM50191196 (1-ethyl-4'-(pyridin-4-yl)-8'-oxa-5',6'-diazaspiro[...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 42 | n/a | n/a | n/a | n/a | n/a | n/a |
Hopital Saint-Louis Curated by ChEMBL | Assay Description Activity at 5HT2B receptor expressed in CHO cell assessed as inhibition of alpha-methyl-5HT-stimulated calcium release | Bioorg Med Chem Lett 16: 4830-3 (2006) Article DOI: 10.1016/j.bmcl.2006.06.068 BindingDB Entry DOI: 10.7270/Q2BV7G7X | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Genome polyprotein (Hepatitis C virus) | BDBM50023507 (CHEMBL3326538) | PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 45 | n/a | n/a | n/a | n/a | n/a | n/a |
IDENIX Pharmaceuticals Curated by ChEMBL | Assay Description Inhibition of full length Hepatitis C virus genotype 1b Con1 NS3/4A by FRET assay | Bioorg Med Chem Lett 24: 4444-9 (2014) Article DOI: 10.1016/j.bmcl.2014.08.002 BindingDB Entry DOI: 10.7270/Q20C4XBK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 2B (Homo sapiens (Human)) | BDBM50191209 (4'-(4-fluorophenyl)-10'-methoxy-1-methyl-8'-oxa-5'...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 46 | n/a | n/a | n/a | n/a | n/a | n/a |
Hopital Saint-Louis Curated by ChEMBL | Assay Description Activity at 5HT2B receptor expressed in CHO cell assessed as inhibition of alpha-methyl-5HT-stimulated calcium release | Bioorg Med Chem Lett 16: 4830-3 (2006) Article DOI: 10.1016/j.bmcl.2006.06.068 BindingDB Entry DOI: 10.7270/Q2BV7G7X | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 2B (Homo sapiens (Human)) | BDBM50191188 (1-methyl-4'-phenyl-8'-oxa-5',6'-diazaspiro[piperid...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 50 | n/a | n/a | n/a | n/a | n/a | n/a |
Hopital Saint-Louis Curated by ChEMBL | Assay Description Activity at 5HT2B receptor expressed in CHO cell assessed as inhibition of alpha-methyl-5HT-stimulated calcium release | Bioorg Med Chem Lett 16: 4830-3 (2006) Article DOI: 10.1016/j.bmcl.2006.06.068 BindingDB Entry DOI: 10.7270/Q2BV7G7X | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 2B (Homo sapiens (Human)) | BDBM50191178 (12'-bromo-1-methyl-4'-phenyl-8'-oxa-5',6'-diazaspi...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 92 | n/a | n/a | n/a | n/a | n/a | n/a |
Hopital Saint-Louis Curated by ChEMBL | Assay Description Activity at 5HT2B receptor expressed in CHO cell assessed as inhibition of alpha-methyl-5HT-stimulated calcium release | Bioorg Med Chem Lett 16: 4830-3 (2006) Article DOI: 10.1016/j.bmcl.2006.06.068 BindingDB Entry DOI: 10.7270/Q2BV7G7X | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 2B (Homo sapiens (Human)) | BDBM50191212 (1-methyl-4'-(pyridin-4-yl)-8'-oxa-5',6'-diazaspiro...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 95 | n/a | n/a | n/a | n/a | n/a | n/a |
Hopital Saint-Louis Curated by ChEMBL | Assay Description Activity at 5HT2B receptor expressed in CHO cell assessed as inhibition of alpha-methyl-5HT-stimulated calcium release | Bioorg Med Chem Lett 16: 4830-3 (2006) Article DOI: 10.1016/j.bmcl.2006.06.068 BindingDB Entry DOI: 10.7270/Q2BV7G7X | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 2B (Homo sapiens (Human)) | BDBM50191187 (12'-bromo-4'-(4-chlorophenyl)-1-methyl-8'-oxa-5',6...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 100 | n/a | n/a | n/a | n/a | n/a | n/a |
Hopital Saint-Louis Curated by ChEMBL | Assay Description Activity at 5HT2B receptor expressed in CHO cell assessed as inhibition of alpha-methyl-5HT-stimulated calcium release | Bioorg Med Chem Lett 16: 4830-3 (2006) Article DOI: 10.1016/j.bmcl.2006.06.068 BindingDB Entry DOI: 10.7270/Q2BV7G7X | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Reverse transcriptase (Human immunodeficiency virus 1) | BDBM50459813 (CHEMBL4205384) | PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | KEGG PC cid PC sid UniChem | Article PubMed | n/a | n/a | 114 | n/a | n/a | n/a | n/a | n/a | n/a |
Idenix an MSD Company Curated by ChEMBL | Assay Description Inhibition of full-length wild-type HIV1 reverse transcriptase expressed in Escherichia coli BL21(DE3) pre-incubated for 30 mins before addition of t... | J Med Chem 61: 9218-9228 (2018) Article DOI: 10.1021/acs.jmedchem.8b00141 BindingDB Entry DOI: 10.7270/Q2NC63TK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 2B (Homo sapiens (Human)) | BDBM50191180 (4'-(4-fluorophenyl)-12'-methyl-1-propyl-8'-oxa-5',...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 115 | n/a | n/a | n/a | n/a | n/a | n/a |
Hopital Saint-Louis Curated by ChEMBL | Assay Description Activity at 5HT2B receptor expressed in CHO cell assessed as inhibition of alpha-methyl-5HT-stimulated calcium release | Bioorg Med Chem Lett 16: 4830-3 (2006) Article DOI: 10.1016/j.bmcl.2006.06.068 BindingDB Entry DOI: 10.7270/Q2BV7G7X | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 2B (Homo sapiens (Human)) | BDBM50191175 (4'-(4-chlorophenyl)-1-(propan-2-yl)-8'-oxa-5',6'-d...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 133 | n/a | n/a | n/a | n/a | n/a | n/a |
Hopital Saint-Louis Curated by ChEMBL | Assay Description Activity at 5HT2B receptor expressed in CHO cell assessed as inhibition of alpha-methyl-5HT-stimulated calcium release | Bioorg Med Chem Lett 16: 4830-3 (2006) Article DOI: 10.1016/j.bmcl.2006.06.068 BindingDB Entry DOI: 10.7270/Q2BV7G7X | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 2B (Homo sapiens (Human)) | BDBM50191211 (12'-bromo-4'-[4-(difluoromethoxy)phenyl]-1-methyl-...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 175 | n/a | n/a | n/a | n/a | n/a | n/a |
Hopital Saint-Louis Curated by ChEMBL | Assay Description Activity at 5HT2B receptor expressed in CHO cell assessed as inhibition of alpha-methyl-5HT-stimulated calcium release | Bioorg Med Chem Lett 16: 4830-3 (2006) Article DOI: 10.1016/j.bmcl.2006.06.068 BindingDB Entry DOI: 10.7270/Q2BV7G7X | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 2B (Homo sapiens (Human)) | BDBM50191172 (12'-bromo-4'-(4-methoxyphenyl)-1-propyl-8'-oxa-5',...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 179 | n/a | n/a | n/a | n/a | n/a | n/a |
Hopital Saint-Louis Curated by ChEMBL | Assay Description Activity at 5HT2B receptor expressed in CHO cell assessed as inhibition of alpha-methyl-5HT-stimulated calcium release | Bioorg Med Chem Lett 16: 4830-3 (2006) Article DOI: 10.1016/j.bmcl.2006.06.068 BindingDB Entry DOI: 10.7270/Q2BV7G7X | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 2B (Homo sapiens (Human)) | BDBM50191185 (12'-bromo-4'-phenyl-1-(propan-2-yl)-8'-oxa-5',6'-d...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 188 | n/a | n/a | n/a | n/a | n/a | n/a |
Hopital Saint-Louis Curated by ChEMBL | Assay Description Activity at 5HT2B receptor expressed in CHO cell assessed as inhibition of alpha-methyl-5HT-stimulated calcium release | Bioorg Med Chem Lett 16: 4830-3 (2006) Article DOI: 10.1016/j.bmcl.2006.06.068 BindingDB Entry DOI: 10.7270/Q2BV7G7X | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Genome polyprotein (Hepatitis C Virus (Virus)) | BDBM426318 (US10513534, Compound 406) | PDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | KEGG PC cid PC sid UniChem | US Patent | n/a | n/a | <250 | n/a | n/a | n/a | n/a | n/a | n/a |
IDENIX PHARMACEUTICALS LLC; CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE; UNIVERSITE DE MONTPELLIER US Patent | Assay Description Test compounds in the form of nucleoside triphosphates were examined for inhibitory activity against purified HCV polymerase in a standard assay. Bac... | US Patent US10513534 (2019) BindingDB Entry DOI: 10.7270/Q2BC41XJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Genome polyprotein (Hepatitis C Virus (Virus)) | BDBM426315 (US10513534, Compound 403) | PDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | KEGG PC cid PC sid UniChem | US Patent | n/a | n/a | <250 | n/a | n/a | n/a | n/a | n/a | n/a |
IDENIX PHARMACEUTICALS LLC; CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE; UNIVERSITE DE MONTPELLIER US Patent | US Patent US10513534 (2019) BindingDB Entry DOI: 10.7270/Q2BC41XJ | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Genome polyprotein (Hepatitis C Virus (Virus)) | BDBM426317 (US10513534, Compound 405) | PDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | KEGG PC cid PC sid UniChem | US Patent | n/a | n/a | <250 | n/a | n/a | n/a | n/a | n/a | n/a |
IDENIX PHARMACEUTICALS LLC; CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE; UNIVERSITE DE MONTPELLIER US Patent | US Patent US10513534 (2019) BindingDB Entry DOI: 10.7270/Q2BC41XJ | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Genome polyprotein (Hepatitis C Virus (Virus)) | BDBM426312 (US10513534, Compound 401) | PDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | KEGG PC cid PC sid UniChem | US Patent | n/a | n/a | <250 | n/a | n/a | n/a | n/a | n/a | n/a |
IDENIX PHARMACEUTICALS LLC; CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE; UNIVERSITE DE MONTPELLIER US Patent | Assay Description Test compounds in the form of nucleoside triphosphates were examined for inhibitory activity against purified HCV polymerase in a standard assay. Bac... | US Patent US10513534 (2019) BindingDB Entry DOI: 10.7270/Q2BC41XJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Genome polyprotein (Hepatitis C Virus (Virus)) | BDBM426319 (US10513534, Compound 407) | PDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | KEGG PC cid PC sid UniChem | US Patent | n/a | n/a | <250 | n/a | n/a | n/a | n/a | n/a | n/a |
IDENIX PHARMACEUTICALS LLC; CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE; UNIVERSITE DE MONTPELLIER US Patent | US Patent US10513534 (2019) BindingDB Entry DOI: 10.7270/Q2BC41XJ | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Reverse transcriptase (Human immunodeficiency virus 1) | BDBM50459816 (CHEMBL518606) | PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | Purchase MCE KEGG PC cid PC sid PDB UniChem | Article PubMed | n/a | n/a | 263 | n/a | n/a | n/a | n/a | n/a | n/a |
Idenix an MSD Company Curated by ChEMBL | Assay Description Inhibition of full-length wild-type HIV1 reverse transcriptase expressed in Escherichia coli BL21(DE3) pre-incubated for 30 mins before addition of t... | J Med Chem 61: 9218-9228 (2018) Article DOI: 10.1021/acs.jmedchem.8b00141 BindingDB Entry DOI: 10.7270/Q2NC63TK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Genome polyprotein (Hepatitis C virus) | BDBM50023581 (CHEMBL3326537) | PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 278 | n/a | n/a | n/a | n/a | n/a | n/a |
IDENIX Pharmaceuticals Curated by ChEMBL | Assay Description Inhibition of full length Hepatitis C virus genotype 1b Con1 NS3/4A by FRET assay | Bioorg Med Chem Lett 24: 4444-9 (2014) Article DOI: 10.1016/j.bmcl.2014.08.002 BindingDB Entry DOI: 10.7270/Q20C4XBK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 2B (Homo sapiens (Human)) | BDBM50191204 (4'-(4-chlorophenyl)-1-methyl-8'-oxa-5',6'-diazaspi...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 280 | n/a | n/a | n/a | n/a | n/a | n/a |
Hopital Saint-Louis Curated by ChEMBL | Assay Description Activity at 5HT2B receptor expressed in CHO cell assessed as inhibition of alpha-methyl-5HT-stimulated calcium release | Bioorg Med Chem Lett 16: 4830-3 (2006) Article DOI: 10.1016/j.bmcl.2006.06.068 BindingDB Entry DOI: 10.7270/Q2BV7G7X | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Reverse transcriptase (Human immunodeficiency virus 1) | BDBM50459815 (CHEMBL4216055) | PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | KEGG PC cid PC sid UniChem | Article PubMed | n/a | n/a | 324 | n/a | n/a | n/a | n/a | n/a | n/a |
Idenix an MSD Company Curated by ChEMBL | Assay Description Inhibition of full-length wild-type HIV1 reverse transcriptase expressed in Escherichia coli BL21(DE3) pre-incubated for 30 mins before addition of t... | J Med Chem 61: 9218-9228 (2018) Article DOI: 10.1021/acs.jmedchem.8b00141 BindingDB Entry DOI: 10.7270/Q2NC63TK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 2B (Homo sapiens (Human)) | BDBM50191206 (1-benzyl-4'-(4-chlorophenyl)-8'-oxa-5',6'-diazaspi...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 350 | n/a | n/a | n/a | n/a | n/a | n/a |
Hopital Saint-Louis Curated by ChEMBL | Assay Description Activity at 5HT2B receptor expressed in CHO cell assessed as inhibition of alpha-methyl-5HT-stimulated calcium release | Bioorg Med Chem Lett 16: 4830-3 (2006) Article DOI: 10.1016/j.bmcl.2006.06.068 BindingDB Entry DOI: 10.7270/Q2BV7G7X | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 2B (Homo sapiens (Human)) | BDBM50191210 (4'-(4-bromophenyl)-1-methyl-8'-oxa-5',6'-diazaspir...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 426 | n/a | n/a | n/a | n/a | n/a | n/a |
Hopital Saint-Louis Curated by ChEMBL | Assay Description Activity at 5HT2B receptor expressed in CHO cell assessed as inhibition of alpha-methyl-5HT-stimulated calcium release | Bioorg Med Chem Lett 16: 4830-3 (2006) Article DOI: 10.1016/j.bmcl.2006.06.068 BindingDB Entry DOI: 10.7270/Q2BV7G7X | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 2B (Homo sapiens (Human)) | BDBM50191199 (12'-bromo-4'-[2-(difluoromethoxy)phenyl]-1-methyl-...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 427 | n/a | n/a | n/a | n/a | n/a | n/a |
Hopital Saint-Louis Curated by ChEMBL | Assay Description Activity at 5HT2B receptor expressed in CHO cell assessed as inhibition of alpha-methyl-5HT-stimulated calcium release | Bioorg Med Chem Lett 16: 4830-3 (2006) Article DOI: 10.1016/j.bmcl.2006.06.068 BindingDB Entry DOI: 10.7270/Q2BV7G7X | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Reverse transcriptase (Human immunodeficiency virus 1) | BDBM50459812 (CHEMBL4214561) | PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | KEGG PC cid PC sid UniChem | Article PubMed | n/a | n/a | 444 | n/a | n/a | n/a | n/a | n/a | n/a |
Idenix an MSD Company Curated by ChEMBL | Assay Description Inhibition of full-length wild-type HIV1 reverse transcriptase expressed in Escherichia coli BL21(DE3) pre-incubated for 30 mins before addition of t... | J Med Chem 61: 9218-9228 (2018) Article DOI: 10.1021/acs.jmedchem.8b00141 BindingDB Entry DOI: 10.7270/Q2NC63TK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 2B (Homo sapiens (Human)) | BDBM50191176 (4'-(2-chlorophenyl)-1-propyl-8'-oxa-5',6'-diazaspi...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 500 | n/a | n/a | n/a | n/a | n/a | n/a |
Hopital Saint-Louis Curated by ChEMBL | Assay Description Activity at 5HT2B receptor expressed in CHO cell assessed as inhibition of alpha-methyl-5HT-stimulated calcium release | Bioorg Med Chem Lett 16: 4830-3 (2006) Article DOI: 10.1016/j.bmcl.2006.06.068 BindingDB Entry DOI: 10.7270/Q2BV7G7X | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Reverse transcriptase (Human immunodeficiency virus 1) | BDBM50459817 (CHEMBL4211088) | PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | KEGG PC cid PC sid UniChem | Article PubMed | n/a | n/a | 523 | n/a | n/a | n/a | n/a | n/a | n/a |
Idenix an MSD Company Curated by ChEMBL | Assay Description Inhibition of full-length wild-type HIV1 reverse transcriptase expressed in Escherichia coli BL21(DE3) pre-incubated for 30 mins before addition of t... | J Med Chem 61: 9218-9228 (2018) Article DOI: 10.1021/acs.jmedchem.8b00141 BindingDB Entry DOI: 10.7270/Q2NC63TK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 2B (Homo sapiens (Human)) | BDBM50191192 (12'-bromo-4'-(3,4-dichlorophenyl)-1-methyl-8'-oxa-...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 542 | n/a | n/a | n/a | n/a | n/a | n/a |
Hopital Saint-Louis Curated by ChEMBL | Assay Description Activity at 5HT2B receptor expressed in CHO cell assessed as inhibition of alpha-methyl-5HT-stimulated calcium release | Bioorg Med Chem Lett 16: 4830-3 (2006) Article DOI: 10.1016/j.bmcl.2006.06.068 BindingDB Entry DOI: 10.7270/Q2BV7G7X | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 2B (Homo sapiens (Human)) | BDBM50191186 (4'-(2-chlorophenyl)-1-methyl-8'-oxa-5',6'-diazaspi...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 753 | n/a | n/a | n/a | n/a | n/a | n/a |
Hopital Saint-Louis Curated by ChEMBL | Assay Description Activity at 5HT2B receptor expressed in CHO cell assessed as inhibition of alpha-methyl-5HT-stimulated calcium release | Bioorg Med Chem Lett 16: 4830-3 (2006) Article DOI: 10.1016/j.bmcl.2006.06.068 BindingDB Entry DOI: 10.7270/Q2BV7G7X | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 2B (Homo sapiens (Human)) | BDBM50191195 (12'-bromo-4'-(4-bromophenyl)-1-propyl-8'-oxa-5',6'...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 791 | n/a | n/a | n/a | n/a | n/a | n/a |
Hopital Saint-Louis Curated by ChEMBL | Assay Description Activity at 5HT2B receptor expressed in CHO cell assessed as inhibition of alpha-methyl-5HT-stimulated calcium release | Bioorg Med Chem Lett 16: 4830-3 (2006) Article DOI: 10.1016/j.bmcl.2006.06.068 BindingDB Entry DOI: 10.7270/Q2BV7G7X | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 2B (Homo sapiens (Human)) | BDBM50191207 (12'-bromo-4'-(2-chlorophenyl)-1-methyl-8'-oxa-5',6...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 856 | n/a | n/a | n/a | n/a | n/a | n/a |
Hopital Saint-Louis Curated by ChEMBL | Assay Description Activity at 5HT2B receptor expressed in CHO cell assessed as inhibition of alpha-methyl-5HT-stimulated calcium release | Bioorg Med Chem Lett 16: 4830-3 (2006) Article DOI: 10.1016/j.bmcl.2006.06.068 BindingDB Entry DOI: 10.7270/Q2BV7G7X | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Genome polyprotein (Hepatitis C virus) | BDBM50023576 (CHEMBL3326827) | PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | <1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
IDENIX Pharmaceuticals Curated by ChEMBL | Assay Description Inhibition of full length Hepatitis C virus genotype 1b Con1 NS3/4A by FRET assay | Bioorg Med Chem Lett 24: 4444-9 (2014) Article DOI: 10.1016/j.bmcl.2014.08.002 BindingDB Entry DOI: 10.7270/Q20C4XBK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Genome polyprotein (Hepatitis C virus) | BDBM50023577 (CHEMBL3326828) | PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | <1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
IDENIX Pharmaceuticals Curated by ChEMBL | Assay Description Inhibition of full length Hepatitis C virus genotype 1b Con1 NS3/4A by FRET assay | Bioorg Med Chem Lett 24: 4444-9 (2014) Article DOI: 10.1016/j.bmcl.2014.08.002 BindingDB Entry DOI: 10.7270/Q20C4XBK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 2B (Homo sapiens (Human)) | BDBM50191203 (4'-(4-bromophenyl)-10'-methoxy-1-methyl-8'-oxa-5',...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.28E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Hopital Saint-Louis Curated by ChEMBL | Assay Description Activity at 5HT2B receptor expressed in CHO cell assessed as inhibition of alpha-methyl-5HT-stimulated calcium release | Bioorg Med Chem Lett 16: 4830-3 (2006) Article DOI: 10.1016/j.bmcl.2006.06.068 BindingDB Entry DOI: 10.7270/Q2BV7G7X | |||||||||||
More data for this Ligand-Target Pair |
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