Compile Data Set for Download or QSAR

Found 85 hits with Last Name = 'vallgårda' and Initial = 'j'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50011261 ((+)7-Dipropylamino-8-methyl-5,6,7,8-tetrahydro-nap...) Show SMILES CCCN(CCC)[C@@H]1CCc2cccc(O)c2[C@@H]1C Show InChI InChI=1S/C17H27NO/c1-4-11-18(12-5-2)15-10-9-14-7-6-8-16(19)17(14)13(15)3/h6-8,13,15,19H,4-5,9-12H2,1-3H3/t13-,15-/m1/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	2.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Uppsala University Curated by ChEMBL					Assay Description Binding affinity at 5-hydroxytryptamine 1A receptor by the displacement of [3H]8-OH-DPAT in rat brain.				J Med Chem 34: 497-510 (1991) BindingDB Entry DOI: 10.7270/Q2PK0GRB
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50051944 (3-((1R,2S)-2-Dipropylamino-cyclopropyl)-phenol | C...) Show SMILES CCCN(CCC)[C@H]1C[C@@H]1c1cccc(O)c1 Show InChI InChI=1S/C15H23NO/c1-3-8-16(9-4-2)15-11-14(15)12-6-5-7-13(17)10-12/h5-7,10,14-15,17H,3-4,8-9,11H2,1-2H3/t14-,15+/m1/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Uppsala University Curated by ChEMBL					Assay Description In vitro binding affinity of compound towards 5-hydroxytryptamine 1A receptor was determined using [3H]-8-OH-DPAT as radioligand; range=2.2-3.2				J Med Chem 39: 1485-93 (1996) Article DOI: 10.1021/jm9507136 BindingDB Entry DOI: 10.7270/Q2RR1ZWN
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50011252 (7-Dipropylamino-8-methyl-5,6,7,8-tetrahydro-naphth...) Show SMILES CCCN(CCC)[C@H]1CCc2cccc(O)c2[C@H]1C Show InChI InChI=1S/C17H27NO/c1-4-11-18(12-5-2)15-10-9-14-7-6-8-16(19)17(14)13(15)3/h6-8,13,15,19H,4-5,9-12H2,1-3H3/t13-,15-/m0/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	2.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Uppsala University Curated by ChEMBL					Assay Description Binding affinity at 5-hydroxytryptamine 1A receptor by the displacement of [3H]8-OH-DPAT in rat brain.				J Med Chem 34: 497-510 (1991) BindingDB Entry DOI: 10.7270/Q2PK0GRB
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50011252 (7-Dipropylamino-8-methyl-5,6,7,8-tetrahydro-naphth...) Show SMILES CCCN(CCC)[C@H]1CCc2cccc(O)c2[C@H]1C Show InChI InChI=1S/C17H27NO/c1-4-11-18(12-5-2)15-10-9-14-7-6-8-16(19)17(14)13(15)3/h6-8,13,15,19H,4-5,9-12H2,1-3H3/t13-,15-/m0/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	2.84	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Uppsala University Curated by ChEMBL					Assay Description Binding affinity at 5-hydroxytryptamine 1A receptor by the displacement of [3H]8-OH-DPAT in rat brain.				J Med Chem 34: 497-510 (1991) BindingDB Entry DOI: 10.7270/Q2PK0GRB
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM21393 (7-(dipropylamino)-5,6,7,8-tetrahydronaphthalen-1-o...) Show SMILES CCCN(CCC)C1CCc2cccc(O)c2C1 Show InChI InChI=1S/C16H25NO/c1-3-10-17(11-4-2)14-9-8-13-6-5-7-16(18)15(13)12-14/h5-7,14,18H,3-4,8-12H2,1-2H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	PubMed	3.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Uppsala University Curated by ChEMBL					Assay Description Binding affinity at 5-hydroxytryptamine 1A receptor by the displacement of [3H]8-OH-DPAT in rat brain.				J Med Chem 34: 497-510 (1991) BindingDB Entry DOI: 10.7270/Q2PK0GRB
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50051945 (2-((1S,2R)-2-Dipropylamino-cyclopropyl)-4-fluoro-p...) Show SMILES CCCN(CCC)[C@@H]1C[C@H]1c1cc(F)ccc1O Show InChI InChI=1S/C15H22FNO/c1-3-7-17(8-4-2)14-10-12(14)13-9-11(16)5-6-15(13)18/h5-6,9,12,14,18H,3-4,7-8,10H2,1-2H3/t12-,14+/m0/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Uppsala University Curated by ChEMBL					Assay Description In vitro binding affinity of compound towards 5-hydroxytryptamine 1A receptor was determined using [3H]8-OH-DPAT as radioligand; range=2.7-3.6				J Med Chem 39: 1485-93 (1996) Article DOI: 10.1021/jm9507136 BindingDB Entry DOI: 10.7270/Q2RR1ZWN
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50011246 (4-Propyl-1,2,3,4,4a,5,6,10b-octahydro-benzo[f]quin...) Show SMILES CCCN1CCC[C@@H]2[C@@H]1CCc1cccc(O)c21 Show InChI InChI=1S/C16H23NO/c1-2-10-17-11-4-6-13-14(17)9-8-12-5-3-7-15(18)16(12)13/h3,5,7,13-14,18H,2,4,6,8-11H2,1H3/t13-,14+/m1/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	3.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Uppsala University Curated by ChEMBL					Assay Description Binding affinity at 5-hydroxytryptamine 1A receptor by the displacement of [3H]8-OH-DPAT in rat brain.				J Med Chem 34: 497-510 (1991) BindingDB Entry DOI: 10.7270/Q2PK0GRB
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50011247 (7-Dipropylamino-5,6,7,8-tetrahydro-naphthalen-1-ol...) Show SMILES CCCN(CCC)[C@H]1CCc2cccc(O)c2C1 Show InChI InChI=1S/C16H25NO/c1-3-10-17(11-4-2)14-9-8-13-6-5-7-16(18)15(13)12-14/h5-7,14,18H,3-4,8-12H2,1-2H3/t14-/m0/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	PubMed	4.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Uppsala University Curated by ChEMBL					Assay Description Binding affinity at 5-hydroxytryptamine 1A receptor by the displacement of [3H]8-OH-DPAT in rat brain.				J Med Chem 34: 497-510 (1991) BindingDB Entry DOI: 10.7270/Q2PK0GRB
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50011264 (2-(2-Dipropylamino-cyclopropyl)-phenol; hydrobromi...) Show SMILES CCCN(CCC)[C@@H]1C[C@H]1c1ccccc1O Show InChI InChI=1S/C15H23NO/c1-3-9-16(10-4-2)14-11-13(14)12-7-5-6-8-15(12)17/h5-8,13-14,17H,3-4,9-11H2,1-2H3/t13-,14+/m0/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Uppsala University Curated by ChEMBL					Assay Description In vitro binding affinity of compound towards 5-hydroxytryptamine 1A receptor was determined using [3H]8-OH-DPAT as radioligand; range=4.6-5.2				J Med Chem 39: 1485-93 (1996) Article DOI: 10.1021/jm9507136 BindingDB Entry DOI: 10.7270/Q2RR1ZWN
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50011247 (7-Dipropylamino-5,6,7,8-tetrahydro-naphthalen-1-ol...) Show SMILES CCCN(CCC)[C@H]1CCc2cccc(O)c2C1 Show InChI InChI=1S/C16H25NO/c1-3-10-17(11-4-2)14-9-8-13-6-5-7-16(18)15(13)12-14/h5-7,14,18H,3-4,8-12H2,1-2H3/t14-/m0/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	PubMed	6.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Uppsala University Curated by ChEMBL					Assay Description Binding affinity at 5-hydroxytryptamine 1A receptor by the displacement of [3H]8-OH-DPAT in rat brain.				J Med Chem 34: 497-510 (1991) BindingDB Entry DOI: 10.7270/Q2PK0GRB
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50453032 (CHEMBL2368632) Show SMILES Br.CCCN(CCC)[C@H]1C[C@H]1c1ccccc1O |r| Show InChI InChI=1S/C15H23NO.BrH/c1-3-9-16(10-4-2)14-11-13(14)12-7-5-6-8-15(12)17;/h5-8,13-14,17H,3-4,9-11H2,1-2H3;1H/t13-,14-;/m0./s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	8	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Uppsala University Curated by ChEMBL					Assay Description Binding affinity at 5-hydroxytryptamine 1A receptor by the displacement of [3H]8-OH-DPAT in rat brain.				J Med Chem 34: 497-510 (1991) BindingDB Entry DOI: 10.7270/Q2PK0GRB
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50051959 (CHEMBL35584 | Dipropyl-((1R,2R)-2-thiophen-2-yl-cy...) Show SMILES CCCN(CCC)[C@@H]1C[C@H]1c1cccs1 Show InChI InChI=1S/C13H21NS/c1-3-7-14(8-4-2)12-10-11(12)13-6-5-9-15-13/h5-6,9,11-12H,3-4,7-8,10H2,1-2H3/t11-,12-/m1/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	11	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Uppsala University Curated by ChEMBL					Assay Description In vitro binding affinity of compound towards 5-hydroxytryptamine 1A receptor was determined using [3H]8-OH-DPAT as radioligand; range=12-14				J Med Chem 39: 1485-93 (1996) Article DOI: 10.1021/jm9507136 BindingDB Entry DOI: 10.7270/Q2RR1ZWN
					More data for this Ligand-Target Pair
11-beta-hydroxysteroid dehydrogenase 1 (Homo sapiens (Human))	BDBM50319660 ((S)-2-((1S,2S,4R)-Bicyclo[2.2.1]heptan-2-ylamino)-...) Show SMILES CC(C)c1sc(N[C@H]2C[C@@H]3CC[C@H]2C3)nc1O |r| Show InChI InChI=1S/C13H20N2OS/c1-7(2)11-12(16)15-13(17-11)14-10-6-8-3-4-9(10)5-8/h7-10,16H,3-6H2,1-2H3,(H,14,15)/t8-,9+,10+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	12.2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Displacement of [3H]-cortisone human 17beta-HSD1 expressed in Escherichia coli after 30 mins by scintillation proximity assay				J Med Chem 53: 4481-7 (2010) Article DOI: 10.1021/jm100242d BindingDB Entry DOI: 10.7270/Q2WW7HVQ
					More data for this Ligand-Target Pair
11-beta-hydroxysteroid dehydrogenase 1 (Homo sapiens (Human))	BDBM50319665 ((S)-2-((1S,2S,4R)-Bicyclo[2.2.1]heptan-2-ylamino)-...) Show SMILES CC(C)[C@]1(C)SC(N[C@H]2C[C@@H]3CC[C@H]2C3)=NC1=O |r,c:16| Show InChI InChI=1S/C14H22N2OS/c1-8(2)14(3)12(17)16-13(18-14)15-11-7-9-4-5-10(11)6-9/h8-11H,4-7H2,1-3H3,(H,15,16,17)/t9-,10+,11+,14+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	12.8	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Displacement of [3H]-cortisone human 17beta-HSD1 expressed in Escherichia coli after 30 mins by scintillation proximity assay				J Med Chem 53: 4481-7 (2010) Article DOI: 10.1021/jm100242d BindingDB Entry DOI: 10.7270/Q2WW7HVQ
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50051946 (CHEMBL37503 | Dipropyl-(2-thiophen-2-yl-cyclopropy...) Show SMILES CCCN(CCC)C1CC1c1cccs1 Show InChI InChI=1S/C13H21NS/c1-3-7-14(8-4-2)12-10-11(12)13-6-5-9-15-13/h5-6,9,11-12H,3-4,7-8,10H2,1-2H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	13	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Uppsala University Curated by ChEMBL					Assay Description In vitro binding affinity of compound towards 5-hydroxytryptamine 1A receptor was determined using [3H]8-OH-DPAT as radioligand; range=12-14				J Med Chem 39: 1485-93 (1996) Article DOI: 10.1021/jm9507136 BindingDB Entry DOI: 10.7270/Q2RR1ZWN
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50051947 (CHEMBL287461 | [(1R,2S)-2-(2-Methoxy-phenyl)-cyclo...) Show SMILES CCCN(CCC)[C@@H]1C[C@H]1c1ccccc1OC Show InChI InChI=1S/C16H25NO/c1-4-10-17(11-5-2)15-12-14(15)13-8-6-7-9-16(13)18-3/h6-9,14-15H,4-5,10-12H2,1-3H3/t14-,15+/m0/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	17	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Uppsala University Curated by ChEMBL					Assay Description In vitro binding affinity of compound towards 5-hydroxytryptamine 1A receptor was determined using [3H]8-OH-DPAT as radioligand; range=16-20				J Med Chem 39: 1485-93 (1996) Article DOI: 10.1021/jm9507136 BindingDB Entry DOI: 10.7270/Q2RR1ZWN
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50453033 (CHEMBL2368621) Show SMILES Br.CCCN(CCC)[C@H]1C[C@H]1c1cccc(O)c1 |r| Show InChI InChI=1S/C15H23NO.BrH/c1-3-8-16(9-4-2)15-11-14(15)12-6-5-7-13(17)10-12;/h5-7,10,14-15,17H,3-4,8-9,11H2,1-2H3;1H/t14-,15-;/m0./s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	17	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Uppsala University Curated by ChEMBL					Assay Description Binding affinity at 5-hydroxytryptamine 1A receptor by the displacement of [3H]8-OH-DPAT in rat brain.				J Med Chem 34: 497-510 (1991) BindingDB Entry DOI: 10.7270/Q2PK0GRB
					More data for this Ligand-Target Pair
11-beta-hydroxysteroid dehydrogenase 1 (Homo sapiens (Human))	BDBM50319664 ((R,S)-2-((+/-)-exo-Bicyclo[2.2.1]heptan-2-ylamino)...) Show SMILES CC(C)C1(C)SC(N[C@H]2C[C@@H]3CC[C@H]2C3)=NC1=O |r,c:16| Show InChI InChI=1S/C14H22N2OS/c1-8(2)14(3)12(17)16-13(18-14)15-11-7-9-4-5-10(11)6-9/h8-11H,4-7H2,1-3H3,(H,15,16,17)/t9-,10+,11+,14?/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	17.3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Displacement of [3H]-cortisone human 17beta-HSD1 expressed in Escherichia coli after 30 mins by scintillation proximity assay				J Med Chem 53: 4481-7 (2010) Article DOI: 10.1021/jm100242d BindingDB Entry DOI: 10.7270/Q2WW7HVQ
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50051958 (CHEMBL543530 | Dipropyl-(2-thiophen-3-yl-cycloprop...) Show SMILES CCCN(CCC)C1CC1c1ccsc1 Show InChI InChI=1S/C13H21NS/c1-3-6-14(7-4-2)13-9-12(13)11-5-8-15-10-11/h5,8,10,12-13H,3-4,6-7,9H2,1-2H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	21	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Uppsala University Curated by ChEMBL					Assay Description In vitro binding affinity of compound towards 5-hydroxytryptamine 1A receptor was determined using [3H]8-OH-DPAT as radioligand; range=19-23				J Med Chem 39: 1485-93 (1996) Article DOI: 10.1021/jm9507136 BindingDB Entry DOI: 10.7270/Q2RR1ZWN
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50051962 (CHEMBL542094 | [2-(2-Bromo-phenyl)-cyclopropyl]-di...) Show SMILES CCCN(CCC)C1CC1c1ccccc1Br Show InChI InChI=1S/C15H22BrN/c1-3-9-17(10-4-2)15-11-13(15)12-7-5-6-8-14(12)16/h5-8,13,15H,3-4,9-11H2,1-2H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	22	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Uppsala University Curated by ChEMBL					Assay Description In vitro binding affinity of compound towards 5-hydroxytryptamine 1A receptor was determined using [3H]8-OH-DPAT as radioligand; range=20-23				J Med Chem 39: 1485-93 (1996) Article DOI: 10.1021/jm9507136 BindingDB Entry DOI: 10.7270/Q2RR1ZWN
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50051949 ((2-Phenyl-cyclopropyl)-dipropyl-amine; hydrochlori...) Show SMILES CCCN(CCC)C1CC1c1ccccc1 Show InChI InChI=1S/C15H23N/c1-3-10-16(11-4-2)15-12-14(15)13-8-6-5-7-9-13/h5-9,14-15H,3-4,10-12H2,1-2H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	24	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Uppsala University Curated by ChEMBL					Assay Description In vitro binding affinity of compound towards 5-hydroxytryptamine 1A receptor was determined using [3H]-8-OH-DPAT as radioligand; range=21-28				J Med Chem 39: 1485-93 (1996) Article DOI: 10.1021/jm9507136 BindingDB Entry DOI: 10.7270/Q2RR1ZWN
					More data for this Ligand-Target Pair
11-beta-hydroxysteroid dehydrogenase 1 (Homo sapiens (Human))	BDBM50319666 ((S)-2-((1R,2R,4S)-Bicyclo[2.2.1]heptan-2-ylamino)-...) Show SMILES CC(C)[C@]1(C)SC(N[C@@H]2C[C@H]3CC[C@@H]2C3)=NC1=O |r,c:16| Show InChI InChI=1S/C14H22N2OS/c1-8(2)14(3)12(17)16-13(18-14)15-11-7-9-4-5-10(11)6-9/h8-11H,4-7H2,1-3H3,(H,15,16,17)/t9-,10+,11+,14-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	27.8	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Displacement of [3H]-cortisone human 17beta-HSD1 expressed in Escherichia coli after 30 mins by scintillation proximity assay				J Med Chem 53: 4481-7 (2010) Article DOI: 10.1021/jm100242d BindingDB Entry DOI: 10.7270/Q2WW7HVQ
					More data for this Ligand-Target Pair
11-beta-hydroxysteroid dehydrogenase 1 (Homo sapiens (Human))	BDBM50319667 ((R)-2-((1S,2S,4R)-Bicyclo[2.2.1]heptan-2-ylamino)-...) Show SMILES CC(C)[C@@]1(C)SC(N[C@H]2C[C@@H]3CC[C@H]2C3)=NC1=O |r,c:16| Show InChI InChI=1S/C14H22N2OS/c1-8(2)14(3)12(17)16-13(18-14)15-11-7-9-4-5-10(11)6-9/h8-11H,4-7H2,1-3H3,(H,15,16,17)/t9-,10+,11+,14-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	30.6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Displacement of [3H]-cortisone human 17beta-HSD1 expressed in Escherichia coli after 30 mins by scintillation proximity assay				J Med Chem 53: 4481-7 (2010) Article DOI: 10.1021/jm100242d BindingDB Entry DOI: 10.7270/Q2WW7HVQ
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50011251 (4-Propyl-1,2,3,4,4a,5,6,10b-octahydro-benzo[f]quin...) Show SMILES CCCN1CCC[C@H]2[C@H]1CCc1cccc(O)c21 Show InChI InChI=1S/C16H23NO/c1-2-10-17-11-4-6-13-14(17)9-8-12-5-3-7-15(18)16(12)13/h3,5,7,13-14,18H,2,4,6,8-11H2,1H3/t13-,14+/m0/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	32	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Uppsala University Curated by ChEMBL					Assay Description Binding affinity at 5-hydroxytryptamine 1A receptor by the displacement of [3H]8-OH-DPAT in rat brain.				J Med Chem 34: 497-510 (1991) BindingDB Entry DOI: 10.7270/Q2PK0GRB
					More data for this Ligand-Target Pair
11-beta-hydroxysteroid dehydrogenase 1 (Homo sapiens (Human))	BDBM50319668 ((R)-2-((1R,2R,4S)-Bicyclo[2.2.1]heptan-2-ylamino)-...) Show SMILES CC(C)[C@@]1(C)SC(N[C@@H]2C[C@H]3CC[C@@H]2C3)=NC1=O |r,c:16| Show InChI InChI=1S/C14H22N2OS/c1-8(2)14(3)12(17)16-13(18-14)15-11-7-9-4-5-10(11)6-9/h8-11H,4-7H2,1-3H3,(H,15,16,17)/t9-,10+,11+,14+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	47.2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Displacement of [3H]-cortisone human 17beta-HSD1 expressed in Escherichia coli after 30 mins by scintillation proximity assay				J Med Chem 53: 4481-7 (2010) Article DOI: 10.1021/jm100242d BindingDB Entry DOI: 10.7270/Q2WW7HVQ
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50011265 ((+)-7-Dipropylamino-6-methyl-5,6,7,8-tetrahydro-na...) Show SMILES CCCN(CCC)[C@H]1Cc2c(O)cccc2C[C@@H]1C Show InChI InChI=1S/C17H27NO/c1-4-9-18(10-5-2)16-12-15-14(11-13(16)3)7-6-8-17(15)19/h6-8,13,16,19H,4-5,9-12H2,1-3H3/t13-,16-/m0/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	49.6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Uppsala University Curated by ChEMBL					Assay Description Binding affinity at 5-hydroxytryptamine 1A receptor by the displacement of [3H]8-OH-DPAT in rat brain.				J Med Chem 34: 497-510 (1991) BindingDB Entry DOI: 10.7270/Q2PK0GRB
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50011265 ((+)-7-Dipropylamino-6-methyl-5,6,7,8-tetrahydro-na...) Show SMILES CCCN(CCC)[C@H]1Cc2c(O)cccc2C[C@@H]1C Show InChI InChI=1S/C17H27NO/c1-4-9-18(10-5-2)16-12-15-14(11-13(16)3)7-6-8-17(15)19/h6-8,13,16,19H,4-5,9-12H2,1-3H3/t13-,16-/m0/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	50	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Uppsala University Curated by ChEMBL					Assay Description Binding affinity at 5-hydroxytryptamine 1A receptor by the displacement of [3H]8-OH-DPAT in rat brain.				J Med Chem 34: 497-510 (1991) BindingDB Entry DOI: 10.7270/Q2PK0GRB
					More data for this Ligand-Target Pair
11-beta-hydroxysteroid dehydrogenase 1 (Homo sapiens (Human))	BDBM50319659 (2-(bicyclo[2.2.1]heptan-2-ylamino)-5-isopropylthia...) Show SMILES CC(C)c1sc(NC2CC3CCC2C3)nc1O Show InChI InChI=1S/C13H20N2OS/c1-7(2)11-12(16)15-13(17-11)14-10-6-8-3-4-9(10)5-8/h7-10,16H,3-6H2,1-2H3,(H,14,15)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	58	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Displacement of [3H]-cortisone human 17beta-HSD1 expressed in Escherichia coli after 30 mins by scintillation proximity assay				J Med Chem 53: 4481-7 (2010) Article DOI: 10.1021/jm100242d BindingDB Entry DOI: 10.7270/Q2WW7HVQ
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50051951 (CHEMBL544005 | [2-(2-Fluoro-phenyl)-cyclopropyl]-d...) Show SMILES CCCN(CCC)C1CC1c1ccccc1F Show InChI InChI=1S/C15H22FN/c1-3-9-17(10-4-2)15-11-13(15)12-7-5-6-8-14(12)16/h5-8,13,15H,3-4,9-11H2,1-2H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	59	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Uppsala University Curated by ChEMBL					Assay Description In vitro binding affinity of compound towards 5-hydroxytryptamine 1A receptor was determined using [3H]-8-OH-DPAT as radioligand; range=48-77				J Med Chem 39: 1485-93 (1996) Article DOI: 10.1021/jm9507136 BindingDB Entry DOI: 10.7270/Q2RR1ZWN
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50051960 (CHEMBL554110 | [(1S,2R)-2-(5-Fluoro-2-methoxy-phen...) Show SMILES CCCN(CCC)[C@H]1C[C@@H]1c1cc(F)ccc1OC Show InChI InChI=1S/C16H24FNO/c1-4-8-18(9-5-2)15-11-13(15)14-10-12(17)6-7-16(14)19-3/h6-7,10,13,15H,4-5,8-9,11H2,1-3H3/t13-,15+/m1/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Uppsala University Curated by ChEMBL					Assay Description In vitro binding affinity of compound towards 5-hydroxytryptamine 1A receptor was determined using [3H]-8-OH-DPAT as radioligand; range=39-87				J Med Chem 39: 1485-93 (1996) Article DOI: 10.1021/jm9507136 BindingDB Entry DOI: 10.7270/Q2RR1ZWN
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50051954 (CHEMBL553030 | [2-(4-Fluoro-phenyl)-cyclopropyl]-d...) Show SMILES CCCN(CCC)C1CC1c1ccc(F)cc1 Show InChI InChI=1S/C15H22FN/c1-3-9-17(10-4-2)15-11-14(15)12-5-7-13(16)8-6-12/h5-8,14-15H,3-4,9-11H2,1-2H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	76	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Uppsala University Curated by ChEMBL					Assay Description In vitro binding affinity of compound towards 5-hydroxytryptamine 1A receptor was determined using [3H]8-OH-DPAT as radioligand; range=63-95				J Med Chem 39: 1485-93 (1996) Article DOI: 10.1021/jm9507136 BindingDB Entry DOI: 10.7270/Q2RR1ZWN
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50051945 (2-((1S,2R)-2-Dipropylamino-cyclopropyl)-4-fluoro-p...) Show SMILES CCCN(CCC)[C@@H]1C[C@H]1c1cc(F)ccc1O Show InChI InChI=1S/C15H22FNO/c1-3-7-17(8-4-2)14-10-12(14)13-9-11(16)5-6-15(13)18/h5-6,9,12,14,18H,3-4,7-8,10H2,1-2H3/t12-,14+/m0/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	99	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Uppsala University Curated by ChEMBL					Assay Description In vitro binding affinity of compound towards 5-hydroxytryptamine 1A receptor was determined using [3H]8-OH-DPAT as radioligand; range=78-140				J Med Chem 39: 1485-93 (1996) Article DOI: 10.1021/jm9507136 BindingDB Entry DOI: 10.7270/Q2RR1ZWN
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50051965 (CHEMBL539499 | [2-(3-Fluoro-phenyl)-cyclopropyl]-d...) Show SMILES CCCN(CCC)C1CC1c1cccc(F)c1 Show InChI InChI=1S/C15H22FN/c1-3-8-17(9-4-2)15-11-14(15)12-6-5-7-13(16)10-12/h5-7,10,14-15H,3-4,8-9,11H2,1-2H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Uppsala University Curated by ChEMBL					Assay Description In vitro binding affinity of compound towards 5-hydroxytryptamine 1A receptor was determined using [3H]8-OH-DPAT as radioligand; range=85-130				J Med Chem 39: 1485-93 (1996) Article DOI: 10.1021/jm9507136 BindingDB Entry DOI: 10.7270/Q2RR1ZWN
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50051960 (CHEMBL554110 | [(1S,2R)-2-(5-Fluoro-2-methoxy-phen...) Show SMILES CCCN(CCC)[C@H]1C[C@@H]1c1cc(F)ccc1OC Show InChI InChI=1S/C16H24FNO/c1-4-8-18(9-5-2)15-11-13(15)14-10-12(17)6-7-16(14)19-3/h6-7,10,13,15H,4-5,8-9,11H2,1-3H3/t13-,15+/m1/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	140	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Uppsala University Curated by ChEMBL					Assay Description In vitro binding affinity of compound towards 5-hydroxytryptamine 1A receptor was determined using [3H]8-OH-DPAT as radioligand; range=89-280				J Med Chem 39: 1485-93 (1996) Article DOI: 10.1021/jm9507136 BindingDB Entry DOI: 10.7270/Q2RR1ZWN
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50051956 (2-((1R,2S)-2-Dipropylamino-cyclopropyl)-phenol | C...) Show SMILES CCCN(CCC)[C@H]1C[C@@H]1c1ccccc1O Show InChI InChI=1S/C15H23NO/c1-3-9-16(10-4-2)14-11-13(14)12-7-5-6-8-15(12)17/h5-8,13-14,17H,3-4,9-11H2,1-2H3/t13-,14+/m1/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	140	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Uppsala University Curated by ChEMBL					Assay Description In vitro binding affinity of compound towards 5-hydroxytryptamine 1A receptor was determined using [3H]8-OH-DPAT as radioligand; range=100-230				J Med Chem 39: 1485-93 (1996) Article DOI: 10.1021/jm9507136 BindingDB Entry DOI: 10.7270/Q2RR1ZWN
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50011248 (1-Propyl-1,2,3,4,4a,5,10,10a-octahydro-benzo[g]qui...) Show SMILES CCCN1CCC[C@H]2Cc3cccc(O)c3C[C@@H]12 Show InChI InChI=1S/C16H23NO/c1-2-8-17-9-4-6-13-10-12-5-3-7-16(18)14(12)11-15(13)17/h3,5,7,13,15,18H,2,4,6,8-11H2,1H3/t13-,15+/m0/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	151	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Uppsala University Curated by ChEMBL					Assay Description Binding affinity at 5-hydroxytryptamine 1A receptor by the displacement of [3H]8-OH-DPAT in rat brain.				J Med Chem 34: 497-510 (1991) BindingDB Entry DOI: 10.7270/Q2PK0GRB
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50051960 (CHEMBL554110 | [(1S,2R)-2-(5-Fluoro-2-methoxy-phen...) Show SMILES CCCN(CCC)[C@H]1C[C@@H]1c1cc(F)ccc1OC Show InChI InChI=1S/C16H24FNO/c1-4-8-18(9-5-2)15-11-13(15)14-10-12(17)6-7-16(14)19-3/h6-7,10,13,15H,4-5,8-9,11H2,1-3H3/t13-,15+/m1/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	199	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Uppsala University Curated by ChEMBL					Assay Description In vitro binding affinity of compound towards 5-hydroxytryptamine 1A receptor was determined using [3H]8-OH-DPAT as radioligand; range=174-224				J Med Chem 39: 1485-93 (1996) Article DOI: 10.1021/jm9507136 BindingDB Entry DOI: 10.7270/Q2RR1ZWN
					More data for this Ligand-Target Pair
11-beta-hydroxysteroid dehydrogenase 1 (Homo sapiens (Human))	BDBM50319661 ((R)-2-((1R,2R,4S)-Bicyclo[2.2.1]heptan-2-ylamino)-...) Show SMILES CC(C)c1sc(N[C@@H]2C[C@H]3CC[C@@H]2C3)nc1O |r| Show InChI InChI=1S/C13H20N2OS/c1-7(2)11-12(16)15-13(17-11)14-10-6-8-3-4-9(10)5-8/h7-10,16H,3-6H2,1-2H3,(H,14,15)/t8-,9+,10+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	227	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Displacement of [3H]-cortisone human 17beta-HSD1 expressed in Escherichia coli after 30 mins by scintillation proximity assay				J Med Chem 53: 4481-7 (2010) Article DOI: 10.1021/jm100242d BindingDB Entry DOI: 10.7270/Q2WW7HVQ
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50051950 (CHEMBL34652 | [(1S,2R)-2-(2-Methoxy-phenyl)-cyclop...) Show SMILES CCCN(CCC)[C@H]1C[C@@H]1c1ccccc1OC Show InChI InChI=1S/C16H25NO/c1-4-10-17(11-5-2)15-12-14(15)13-8-6-7-9-16(13)18-3/h6-9,14-15H,4-5,10-12H2,1-3H3/t14-,15+/m1/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	230	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Uppsala University Curated by ChEMBL					Assay Description In vitro binding affinity of compound towards 5-hydroxytryptamine 1A receptor was determined using [3H]8-OH-DPAT as radioligand; range=160-430				J Med Chem 39: 1485-93 (1996) Article DOI: 10.1021/jm9507136 BindingDB Entry DOI: 10.7270/Q2RR1ZWN
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50051953 (CHEMBL544947 | [2-(2,3-Dichloro-phenyl)-cyclopropy...) Show SMILES CCCN(CCC)C1CC1c1cccc(Cl)c1Cl Show InChI InChI=1S/C15H21Cl2N/c1-3-8-18(9-4-2)14-10-12(14)11-6-5-7-13(16)15(11)17/h5-7,12,14H,3-4,8-10H2,1-2H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	>300	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Uppsala University Curated by ChEMBL					Assay Description In vitro binding affinity of compound towards 5-hydroxytryptamine 1A receptor was determined using [3H]8-OH-DPAT as radioligand				J Med Chem 39: 1485-93 (1996) Article DOI: 10.1021/jm9507136 BindingDB Entry DOI: 10.7270/Q2RR1ZWN
					More data for this Ligand-Target Pair
11-beta-hydroxysteroid dehydrogenase 1 (Homo sapiens (Human))	BDBM50319660 ((S)-2-((1S,2S,4R)-Bicyclo[2.2.1]heptan-2-ylamino)-...) Show SMILES CC(C)c1sc(N[C@H]2C[C@@H]3CC[C@H]2C3)nc1O |r| Show InChI InChI=1S/C13H20N2OS/c1-7(2)11-12(16)15-13(17-11)14-10-6-8-3-4-9(10)5-8/h7-10,16H,3-6H2,1-2H3,(H,14,15)/t8-,9+,10+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	329	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Displacement of [3H]-cortisone human 17beta-HSD1 expressed in Escherichia coli after 30 mins by scintillation proximity assay				J Med Chem 53: 4481-7 (2010) Article DOI: 10.1021/jm100242d BindingDB Entry DOI: 10.7270/Q2WW7HVQ
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50051945 (2-((1S,2R)-2-Dipropylamino-cyclopropyl)-4-fluoro-p...) Show SMILES CCCN(CCC)[C@@H]1C[C@H]1c1cc(F)ccc1O Show InChI InChI=1S/C15H22FNO/c1-3-7-17(8-4-2)14-10-12(14)13-9-11(16)5-6-15(13)18/h5-6,9,12,14,18H,3-4,7-8,10H2,1-2H3/t12-,14+/m0/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	348	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Uppsala University Curated by ChEMBL					Assay Description In vitro binding affinity of compound towards 5-hydroxytryptamine 1A receptor was determined using [3H]8-OH-DPAT as radioligand; range=184-503				J Med Chem 39: 1485-93 (1996) Article DOI: 10.1021/jm9507136 BindingDB Entry DOI: 10.7270/Q2RR1ZWN
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50011262 (7-Dipropylamino-6-methyl-5,6,7,8-tetrahydro-naphth...) Show SMILES CCCN(CCC)[C@@H]1Cc2c(O)cccc2C[C@@H]1C Show InChI InChI=1S/C17H27NO/c1-4-9-18(10-5-2)16-12-15-14(11-13(16)3)7-6-8-17(15)19/h6-8,13,16,19H,4-5,9-12H2,1-3H3/t13-,16+/m0/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	394	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Uppsala University Curated by ChEMBL					Assay Description Binding affinity at 5-hydroxytryptamine 1A receptor by the displacement of [3H]8-OH-DPAT in rat brain.				J Med Chem 34: 497-510 (1991) BindingDB Entry DOI: 10.7270/Q2PK0GRB
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50011260 (3-(2-Dipropylamino-cyclopropyl)-phenol; hydrobromi...) Show SMILES CCCN(CCC)[C@@H]1C[C@H]1c1cccc(O)c1 Show InChI InChI=1S/C15H23NO/c1-3-8-16(9-4-2)15-11-14(15)12-6-5-7-13(17)10-12/h5-7,10,14-15,17H,3-4,8-9,11H2,1-2H3/t14-,15+/m0/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	460	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Uppsala University Curated by ChEMBL					Assay Description In vitro binding affinity of compound towards 5-hydroxytryptamine 1A receptor was determined using [3H]8-OH-DPAT as radioligand; range=240-760				J Med Chem 39: 1485-93 (1996) Article DOI: 10.1021/jm9507136 BindingDB Entry DOI: 10.7270/Q2RR1ZWN
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50368163 (CHEMBL545098) Show SMILES CCCN(CCC)[C@@H]1C[C@@H]1c1cccc(O)c1 |r| Show InChI InChI=1S/C15H23NO/c1-3-8-16(9-4-2)15-11-14(15)12-6-5-7-13(17)10-12/h5-7,10,14-15,17H,3-4,8-9,11H2,1-2H3/t14-,15-/m1/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	501	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Uppsala University Curated by ChEMBL					Assay Description Binding affinity at 5-hydroxytryptamine 1A receptor by the displacement of [3H]8-OH-DPAT in rat brain.				J Med Chem 34: 497-510 (1991) BindingDB Entry DOI: 10.7270/Q2PK0GRB
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50011256 ((+)-7-Dipropylamino-6-methyl-5,6,7,8-tetrahydro-na...) Show SMILES CCCN(CCC)[C@H]1Cc2c(O)cccc2C[C@H]1C Show InChI InChI=1S/C17H27NO/c1-4-9-18(10-5-2)16-12-15-14(11-13(16)3)7-6-8-17(15)19/h6-8,13,16,19H,4-5,9-12H2,1-3H3/t13-,16+/m1/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	656	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Uppsala University Curated by ChEMBL					Assay Description Binding affinity at 5-hydroxytryptamine 1A receptor by the displacement of [3H]8-OH-DPAT in rat brain.				J Med Chem 34: 497-510 (1991) BindingDB Entry DOI: 10.7270/Q2PK0GRB
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50011256 ((+)-7-Dipropylamino-6-methyl-5,6,7,8-tetrahydro-na...) Show SMILES CCCN(CCC)[C@H]1Cc2c(O)cccc2C[C@H]1C Show InChI InChI=1S/C17H27NO/c1-4-9-18(10-5-2)16-12-15-14(11-13(16)3)7-6-8-17(15)19/h6-8,13,16,19H,4-5,9-12H2,1-3H3/t13-,16+/m1/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	656	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Uppsala University Curated by ChEMBL					Assay Description Binding affinity at 5-hydroxytryptamine 1A receptor by the displacement of [3H]8-OH-DPAT in rat brain.				J Med Chem 34: 497-510 (1991) BindingDB Entry DOI: 10.7270/Q2PK0GRB
					More data for this Ligand-Target Pair
11-beta-hydroxysteroid dehydrogenase 1 (Homo sapiens (Human))	BDBM50319661 ((R)-2-((1R,2R,4S)-Bicyclo[2.2.1]heptan-2-ylamino)-...) Show SMILES CC(C)c1sc(N[C@@H]2C[C@H]3CC[C@@H]2C3)nc1O |r| Show InChI InChI=1S/C13H20N2OS/c1-7(2)11-12(16)15-13(17-11)14-10-6-8-3-4-9(10)5-8/h7-10,16H,3-6H2,1-2H3,(H,14,15)/t8-,9+,10+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	770	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Displacement of [3H]-cortisone human 17beta-HSD1 expressed in Escherichia coli after 30 mins by scintillation proximity assay				J Med Chem 53: 4481-7 (2010) Article DOI: 10.1021/jm100242d BindingDB Entry DOI: 10.7270/Q2WW7HVQ
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50051952 (CHEMBL34989 | Dipropyl-((1S,2S)-2-thiophen-2-yl-cy...) Show SMILES CCCN(CCC)[C@H]1C[C@@H]1c1cccs1 Show InChI InChI=1S/C13H21NS/c1-3-7-14(8-4-2)12-10-11(12)13-6-5-9-15-13/h5-6,9,11-12H,3-4,7-8,10H2,1-2H3/t11-,12-/m0/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	820	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Uppsala University Curated by ChEMBL					Assay Description In vitro binding affinity of compound towards 5-hydroxytryptamine 1A receptor was determined using [3H]8-OH-DPAT as radioligand; range=710-980				J Med Chem 39: 1485-93 (1996) Article DOI: 10.1021/jm9507136 BindingDB Entry DOI: 10.7270/Q2RR1ZWN
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50368165 (CHEMBL540354) Show SMILES CCCN(CCC)[C@@H]1C[C@@H]1c1ccccc1O |r| Show InChI InChI=1S/C15H23NO/c1-3-9-16(10-4-2)14-11-13(14)12-7-5-6-8-15(12)17/h5-8,13-14,17H,3-4,9-11H2,1-2H3/t13-,14-/m1/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	923	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Uppsala University Curated by ChEMBL					Assay Description Binding affinity at 5-hydroxytryptamine 1A receptor by the displacement of [3H]8-OH-DPAT in rat brain.				J Med Chem 34: 497-510 (1991) BindingDB Entry DOI: 10.7270/Q2PK0GRB
					More data for this Ligand-Target Pair

Displayed 1 to 50 (of 85 total )  |  Next  |  Last  >>

Jump to: