BindingDB PrimarySearch

Found 216 hits with Last Name = 'yli-kauhaluoma' and Initial = 'j'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Protein kinase C delta type (Homo sapiens (Human))	BDBM50258529 (CHEMBL449158 \| bryostatin 1) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	0.440	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Helsinki Curated by ChEMBL					Assay Description Displacement of [3H]PDBu from human recombinant PKCdelta expressed in Sf9 cells by liquid scintillation counting				J Med Chem 52: 3969-81 (2009) Article DOI: 10.1021/jm900229p BindingDB Entry DOI: 10.7270/Q2ZK5GJ1
University of Helsinki Curated by ChEMBL					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM50000092 ((-)-(etorphine) \| (-)-morphine \| (1S,5R,13R,14S)-1...) Show SMILES Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank PDB Article PubMed	4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Helsinki Curated by ChEMBL					Assay Description Displacement of [3H]diprenorphine from human MOR expressed in African green monkey COS1 cell membranes incubated for 1 hr by scintillation counting m...				Eur J Med Chem 151: 495-507 (2018) Article DOI: 10.1016/j.ejmech.2018.02.074 BindingDB Entry DOI: 10.7270/Q2NK3HKB
University of Helsinki Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
UDP-glucuronosyltransferase 2B7 (Homo sapiens (Human))	BDBM50211740 ((1R)-phenyl-[(1R,2S,7S,8S,9S)-3,3,7-trimethyltricy...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	18.4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Helsinki Curated by ChEMBL					Assay Description Inhibition of human UGT2B7 assessed as reduction of estriol glucuronidation				J Med Chem 50: 2655-64 (2007) Article DOI: 10.1021/jm061204e BindingDB Entry DOI: 10.7270/Q23F4QF2
University of Helsinki Curated by ChEMBL					More data for this Ligand-Target Pair
Protein kinase C alpha type (Homo sapiens (Human))	BDBM50015677 ((S)-1-hydroxymethyl-2-octanoyloxy-ethyl ester \| 1,...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Helsinki Curated by ChEMBL					Assay Description Displacement of [3H]PDBu from human recombinant PKCalpha expressed in Sf9 cells by liquid scintillation counting				J Med Chem 52: 3969-81 (2009) Article DOI: 10.1021/jm900229p BindingDB Entry DOI: 10.7270/Q2ZK5GJ1
University of Helsinki Curated by ChEMBL					More data for this Ligand-Target Pair
Protein kinase C alpha type (Homo sapiens (Human))	BDBM50258472 (CHEMBL466211 \| bis(3-(trifluoromethyl)benzyl)5-(hy...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	205	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Helsinki Curated by ChEMBL					Assay Description Displacement of [3H]PDBu from human recombinant PKCalpha expressed in Sf9 cells by liquid scintillation counting				J Med Chem 52: 3969-81 (2009) Article DOI: 10.1021/jm900229p BindingDB Entry DOI: 10.7270/Q2ZK5GJ1
University of Helsinki Curated by ChEMBL					More data for this Ligand-Target Pair
Protein kinase C alpha type (Homo sapiens (Human))	BDBM50258322 (CHEMBL494361 \| diheptan-3-yl 5-(hydroxymethyl)isop...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	319	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Helsinki Curated by ChEMBL					Assay Description Displacement of [3H]PDBu from human recombinant PKCalpha expressed in Sf9 cells by liquid scintillation counting				J Med Chem 52: 3969-81 (2009) Article DOI: 10.1021/jm900229p BindingDB Entry DOI: 10.7270/Q2ZK5GJ1
University of Helsinki Curated by ChEMBL					More data for this Ligand-Target Pair
Delta-type opioid receptor (Homo sapiens (Human))	BDBM50000092 ((-)-(etorphine) \| (-)-morphine \| (1S,5R,13R,14S)-1...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank Article PubMed	340	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Helsinki Curated by ChEMBL					Assay Description Displacement of [3H]diprenorphine from human DOR expressed in African green monkey COS1 cell membranes incubated for 1 hr by scintillation counting m...				Eur J Med Chem 151: 495-507 (2018) Article DOI: 10.1016/j.ejmech.2018.02.074 BindingDB Entry DOI: 10.7270/Q2NK3HKB
University of Helsinki Curated by ChEMBL					More data for this Ligand-Target Pair
Protein kinase C delta type (Homo sapiens (Human))	BDBM50258322 (CHEMBL494361 \| diheptan-3-yl 5-(hydroxymethyl)isop...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	529	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Helsinki Curated by ChEMBL					Assay Description Displacement of [3H]PDBu from human recombinant PKCdelta expressed in Sf9 cells by liquid scintillation counting				J Med Chem 52: 3969-81 (2009) Article DOI: 10.1021/jm900229p BindingDB Entry DOI: 10.7270/Q2ZK5GJ1
University of Helsinki Curated by ChEMBL					More data for this Ligand-Target Pair
Protein kinase C delta type (Homo sapiens (Human))	BDBM50258472 (CHEMBL466211 \| bis(3-(trifluoromethyl)benzyl)5-(hy...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	590	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Helsinki Curated by ChEMBL					Assay Description Displacement of [3H]PDBu from human recombinant PKCdelta expressed in Sf9 cells by liquid scintillation counting				J Med Chem 52: 3969-81 (2009) Article DOI: 10.1021/jm900229p BindingDB Entry DOI: 10.7270/Q2ZK5GJ1
University of Helsinki Curated by ChEMBL					More data for this Ligand-Target Pair
Protein kinase C alpha type (Homo sapiens (Human))	BDBM50258321 (CHEMBL523053 \| dihexan-3-yl 5-(hydroxymethyl)isoph...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	661	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Helsinki Curated by ChEMBL					Assay Description Displacement of [3H]PDBu from human recombinant PKCalpha expressed in Sf9 cells by liquid scintillation counting				J Med Chem 52: 3969-81 (2009) Article DOI: 10.1021/jm900229p BindingDB Entry DOI: 10.7270/Q2ZK5GJ1
University of Helsinki Curated by ChEMBL					More data for this Ligand-Target Pair
Botulinum neurotoxin type A (Clostridium botulinum)	BDBM50340404 (28-Hemisuccinylbetulin \| CHEMBL1761333) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	800	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Inhibition of Clostridium BoNT/A protease light chain				Bioorg Med Chem Lett 21: 2229-31 (2011) Article DOI: 10.1016/j.bmcl.2011.02.115 BindingDB Entry DOI: 10.7270/Q2KS6RWV
The Scripps Research Institute Curated by ChEMBL					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM50370401 (CHEMBL4168822) Show SMILES Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	814	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Helsinki Curated by ChEMBL					Assay Description Displacement of [3H]diprenorphine from human MOR expressed in African green monkey COS1 cell membranes incubated for 1 hr by scintillation counting m...				Eur J Med Chem 151: 495-507 (2018) Article DOI: 10.1016/j.ejmech.2018.02.074 BindingDB Entry DOI: 10.7270/Q2NK3HKB
University of Helsinki Curated by ChEMBL					More data for this Ligand-Target Pair
Protein kinase C delta type (Homo sapiens (Human))	BDBM50258321 (CHEMBL523053 \| dihexan-3-yl 5-(hydroxymethyl)isoph...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	915	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Helsinki Curated by ChEMBL					Assay Description Displacement of [3H]PDBu from human recombinant PKCdelta expressed in Sf9 cells by liquid scintillation counting				J Med Chem 52: 3969-81 (2009) Article DOI: 10.1021/jm900229p BindingDB Entry DOI: 10.7270/Q2ZK5GJ1
University of Helsinki Curated by ChEMBL					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM50370393 (CHEMBL4168247) Show SMILES Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	1.08E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Helsinki Curated by ChEMBL					Assay Description Displacement of [3H]diprenorphine from human MOR expressed in African green monkey COS1 cell membranes incubated for 1 hr by scintillation counting m...				Eur J Med Chem 151: 495-507 (2018) Article DOI: 10.1016/j.ejmech.2018.02.074 BindingDB Entry DOI: 10.7270/Q2NK3HKB
University of Helsinki Curated by ChEMBL					More data for this Ligand-Target Pair
Delta-type opioid receptor (Homo sapiens (Human))	BDBM50370393 (CHEMBL4168247) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	1.13E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Helsinki Curated by ChEMBL					Assay Description Displacement of [3H]diprenorphine from human DOR expressed in African green monkey COS1 cell membranes incubated for 1 hr by scintillation counting m...				Eur J Med Chem 151: 495-507 (2018) Article DOI: 10.1016/j.ejmech.2018.02.074 BindingDB Entry DOI: 10.7270/Q2NK3HKB
University of Helsinki Curated by ChEMBL					More data for this Ligand-Target Pair
Delta-type opioid receptor (Homo sapiens (Human))	BDBM50370401 (CHEMBL4168822) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	1.69E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Helsinki Curated by ChEMBL					Assay Description Displacement of [3H]diprenorphine from human DOR expressed in African green monkey COS1 cell membranes incubated for 1 hr by scintillation counting m...				Eur J Med Chem 151: 495-507 (2018) Article DOI: 10.1016/j.ejmech.2018.02.074 BindingDB Entry DOI: 10.7270/Q2NK3HKB
University of Helsinki Curated by ChEMBL					More data for this Ligand-Target Pair
Orexin/Hypocretin receptor type 1 (Homo sapiens (Human))	BDBM50468969 (CHEMBL4295121) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	3.10E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Helsinki Curated by ChEMBL					Assay Description Antagonist activity at human OX1 receptor expressed in CHOK1 cells assessed as inhibition of orexin-A-induced calcium accumulation preincubated for 3...				Eur J Med Chem 157: 88-100 (2018) Article DOI: 10.1016/j.ejmech.2018.07.040 BindingDB Entry DOI: 10.7270/Q2TQ647C
University of Helsinki Curated by ChEMBL					More data for this Ligand-Target Pair
Orexin receptor type 2 (Homo sapiens (Human))	BDBM50468969 (CHEMBL4295121) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	3.20E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Helsinki Curated by ChEMBL					Assay Description Antagonist activity at human OX2 receptor expressed in CHOK1 cells assessed as inhibition of orexin-A-induced calcium accumulation preincubated for 3...				Eur J Med Chem 157: 88-100 (2018) Article DOI: 10.1016/j.ejmech.2018.07.040 BindingDB Entry DOI: 10.7270/Q2TQ647C
University of Helsinki Curated by ChEMBL					More data for this Ligand-Target Pair
Orexin receptor type 2 (Homo sapiens (Human))	BDBM50468970 (CHEMBL4281212) Show SMILES COC(=O)c1cccc2c(C=O)cc(I)c2c1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	3.60E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Helsinki Curated by ChEMBL					Assay Description Antagonist activity at human OX2 receptor expressed in CHOK1 cells assessed as inhibition of orexin-A-induced calcium accumulation preincubated for 3...				Eur J Med Chem 157: 88-100 (2018) Article DOI: 10.1016/j.ejmech.2018.07.040 BindingDB Entry DOI: 10.7270/Q2TQ647C
University of Helsinki Curated by ChEMBL					More data for this Ligand-Target Pair
Orexin receptor type 2 (Homo sapiens (Human))	BDBM50468971 (CHEMBL4291497) Show SMILES COC(=O)c1cc(CN2CCOCC2)c2ccc(Cl)ccc12 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	4.30E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Helsinki Curated by ChEMBL					Assay Description Antagonist activity at human OX2 receptor expressed in CHOK1 cells assessed as inhibition of orexin-A-induced calcium accumulation preincubated for 3...				Eur J Med Chem 157: 88-100 (2018) Article DOI: 10.1016/j.ejmech.2018.07.040 BindingDB Entry DOI: 10.7270/Q2TQ647C
University of Helsinki Curated by ChEMBL					More data for this Ligand-Target Pair
Orexin/Hypocretin receptor type 1 (Homo sapiens (Human))	BDBM50468970 (CHEMBL4281212) Show SMILES COC(=O)c1cccc2c(C=O)cc(I)c2c1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	4.80E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Helsinki Curated by ChEMBL					Assay Description Antagonist activity at human OX1 receptor expressed in CHOK1 cells assessed as inhibition of orexin-A-induced calcium accumulation preincubated for 3...				Eur J Med Chem 157: 88-100 (2018) Article DOI: 10.1016/j.ejmech.2018.07.040 BindingDB Entry DOI: 10.7270/Q2TQ647C
University of Helsinki Curated by ChEMBL					More data for this Ligand-Target Pair
Orexin/Hypocretin receptor type 1 (Homo sapiens (Human))	BDBM50468971 (CHEMBL4291497) Show SMILES COC(=O)c1cc(CN2CCOCC2)c2ccc(Cl)ccc12 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	5.40E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Helsinki Curated by ChEMBL					Assay Description Antagonist activity at human OX1 receptor expressed in CHOK1 cells assessed as inhibition of orexin-A-induced calcium accumulation preincubated for 3...				Eur J Med Chem 157: 88-100 (2018) Article DOI: 10.1016/j.ejmech.2018.07.040 BindingDB Entry DOI: 10.7270/Q2TQ647C
University of Helsinki Curated by ChEMBL					More data for this Ligand-Target Pair
Botulinum neurotoxin type A (Clostridium botulinum)	BDBM50340405 (Betulinyl 28-carboxymethoxycarvacrolate \| CHEMBL10...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	1.33E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Inhibition of Clostridium BoNT/A protease light chain				Bioorg Med Chem Lett 21: 2229-31 (2011) Article DOI: 10.1016/j.bmcl.2011.02.115 BindingDB Entry DOI: 10.7270/Q2KS6RWV
The Scripps Research Institute Curated by ChEMBL					More data for this Ligand-Target Pair
Botulinum neurotoxin type A (Clostridium botulinum)	BDBM23208 ((1R,2R,5S,8R,9R,10R,13R,14R,17S,19R)-17-hydroxy-1,...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	1.43E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Inhibition of Clostridium BoNT/A protease light chain				Bioorg Med Chem Lett 21: 2229-31 (2011) Article DOI: 10.1016/j.bmcl.2011.02.115 BindingDB Entry DOI: 10.7270/Q2KS6RWV
The Scripps Research Institute Curated by ChEMBL					More data for this Ligand-Target Pair
UDP-glucuronosyltransferase 2B17 (Homo sapiens (Human))	BDBM50211740 ((1R)-phenyl-[(1R,2S,7S,8S,9S)-3,3,7-trimethyltricy...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.18E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Helsinki Curated by ChEMBL					Assay Description Inhibition of human recombinant UGT2B17 assessed as reduction of scopoletin glucuronidation				J Med Chem 50: 2655-64 (2007) Article DOI: 10.1021/jm061204e BindingDB Entry DOI: 10.7270/Q23F4QF2
University of Helsinki Curated by ChEMBL					More data for this Ligand-Target Pair
UDP-glucuronosyltransferase 2B17 (Homo sapiens (Human))	BDBM50183611 ((rac)-5,7-dimethyl-1,2,3,4-tetrahydronaphthalen-1-...) Show SMILES Cc1cc(C)c2CCCC(O)c2c1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	5.78E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Helsinki Curated by ChEMBL					Assay Description Competitive inhibition of UGT2B17-catalyzed scopoletin glucuronidation				J Med Chem 49: 1818-27 (2006) Article DOI: 10.1021/jm051142c BindingDB Entry DOI: 10.7270/Q2B857QP
University of Helsinki Curated by ChEMBL					More data for this Ligand-Target Pair
UDP-glucuronosyltransferase 2B7 (Homo sapiens (Human))	BDBM50183611 ((rac)-5,7-dimethyl-1,2,3,4-tetrahydronaphthalen-1-...) Show SMILES Cc1cc(C)c2CCCC(O)c2c1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.01E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Helsinki Curated by ChEMBL					Assay Description Competitive inhibition of UGT2B7-catalyzed scopoletin glucuronidation				J Med Chem 49: 1818-27 (2006) Article DOI: 10.1021/jm051142c BindingDB Entry DOI: 10.7270/Q2B857QP
University of Helsinki Curated by ChEMBL					More data for this Ligand-Target Pair
UDP-glucuronosyltransferase 2B7 (Homo sapiens (Human))	BDBM50183598 ((rac)-6-methyl-3,4-dihydro-2H-chromen-4-ol \| CHEMB...) Show SMILES Cc1ccc2OCCC(O)c2c1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	1.13E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Helsinki Curated by ChEMBL					Assay Description Competitive inhibition of UGT2B7-catalyzed scopoletin glucuronidation				J Med Chem 49: 1818-27 (2006) Article DOI: 10.1021/jm051142c BindingDB Entry DOI: 10.7270/Q2B857QP
University of Helsinki Curated by ChEMBL					More data for this Ligand-Target Pair
UDP-glucuronosyltransferase 2B17 (Homo sapiens (Human))	BDBM50183611 ((rac)-5,7-dimethyl-1,2,3,4-tetrahydronaphthalen-1-...) Show SMILES Cc1cc(C)c2CCCC(O)c2c1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.90E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Helsinki Curated by ChEMBL					Assay Description Non competitive inhibition of UGT2B17-catalyzed scopoletin glucuronidation				J Med Chem 49: 1818-27 (2006) Article DOI: 10.1021/jm051142c BindingDB Entry DOI: 10.7270/Q2B857QP
University of Helsinki Curated by ChEMBL					More data for this Ligand-Target Pair
UDP-glucuronosyltransferase 2B7 (Homo sapiens (Human))	BDBM50183611 ((rac)-5,7-dimethyl-1,2,3,4-tetrahydronaphthalen-1-...) Show SMILES Cc1cc(C)c2CCCC(O)c2c1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.92E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Helsinki Curated by ChEMBL					Assay Description Non competitive inhibition of UGT2B7-catalyzed scopoletin glucuronidation				J Med Chem 49: 1818-27 (2006) Article DOI: 10.1021/jm051142c BindingDB Entry DOI: 10.7270/Q2B857QP
University of Helsinki Curated by ChEMBL					More data for this Ligand-Target Pair
UDP-glucuronosyltransferase 2B17 (Homo sapiens (Human))	BDBM50183598 ((rac)-6-methyl-3,4-dihydro-2H-chromen-4-ol \| CHEMB...) Show SMILES Cc1ccc2OCCC(O)c2c1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	2.01E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Helsinki Curated by ChEMBL					Assay Description Competitive inhibition of UGT2B17-catalyzed scopoletin glucuronidation				J Med Chem 49: 1818-27 (2006) Article DOI: 10.1021/jm051142c BindingDB Entry DOI: 10.7270/Q2B857QP
University of Helsinki Curated by ChEMBL					More data for this Ligand-Target Pair
UDP-glucuronosyltransferase 2B7 (Homo sapiens (Human))	BDBM50183598 ((rac)-6-methyl-3,4-dihydro-2H-chromen-4-ol \| CHEMB...) Show SMILES Cc1ccc2OCCC(O)c2c1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	2.58E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Helsinki Curated by ChEMBL					Assay Description Non competitive inhibition of UGT2B7-catalyzed scopoletin glucuronidation				J Med Chem 49: 1818-27 (2006) Article DOI: 10.1021/jm051142c BindingDB Entry DOI: 10.7270/Q2B857QP
University of Helsinki Curated by ChEMBL					More data for this Ligand-Target Pair
UDP-glucuronosyltransferase 2B7 (Homo sapiens (Human))	BDBM50183609 ((rac)-6-methyl-2,3-dihydro-1H-inden-1-ol \| CHEMBL2...) Show SMILES Cc1ccc2CCC(O)c2c1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	3.01E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Helsinki Curated by ChEMBL					Assay Description Competitive inhibition of UGT2B7-catalyzed scopoletin glucuronidation				J Med Chem 49: 1818-27 (2006) Article DOI: 10.1021/jm051142c BindingDB Entry DOI: 10.7270/Q2B857QP
University of Helsinki Curated by ChEMBL					More data for this Ligand-Target Pair
UDP-glucuronosyltransferase 2B17 (Homo sapiens (Human))	BDBM50183609 ((rac)-6-methyl-2,3-dihydro-1H-inden-1-ol \| CHEMBL2...) Show SMILES Cc1ccc2CCC(O)c2c1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	4.27E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Helsinki Curated by ChEMBL					Assay Description Competitive inhibition of UGT2B17-catalyzed scopoletin glucuronidation				J Med Chem 49: 1818-27 (2006) Article DOI: 10.1021/jm051142c BindingDB Entry DOI: 10.7270/Q2B857QP
University of Helsinki Curated by ChEMBL					More data for this Ligand-Target Pair
UDP-glucuronosyltransferase 2B17 (Homo sapiens (Human))	BDBM50183598 ((rac)-6-methyl-3,4-dihydro-2H-chromen-4-ol \| CHEMB...) Show SMILES Cc1ccc2OCCC(O)c2c1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	6.08E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Helsinki Curated by ChEMBL					Assay Description Non competitive inhibition of UGT2B17-catalyzed scopoletin glucuronidation				J Med Chem 49: 1818-27 (2006) Article DOI: 10.1021/jm051142c BindingDB Entry DOI: 10.7270/Q2B857QP
University of Helsinki Curated by ChEMBL					More data for this Ligand-Target Pair
UDP-glucuronosyltransferase 2B7 (Homo sapiens (Human))	BDBM50183609 ((rac)-6-methyl-2,3-dihydro-1H-inden-1-ol \| CHEMBL2...) Show SMILES Cc1ccc2CCC(O)c2c1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	6.24E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Helsinki Curated by ChEMBL					Assay Description Non competitive inhibition of UGT2B7-catalyzed scopoletin glucuronidation				J Med Chem 49: 1818-27 (2006) Article DOI: 10.1021/jm051142c BindingDB Entry DOI: 10.7270/Q2B857QP
University of Helsinki Curated by ChEMBL					More data for this Ligand-Target Pair
UDP-glucuronosyltransferase 2B17 (Homo sapiens (Human))	BDBM50183609 ((rac)-6-methyl-2,3-dihydro-1H-inden-1-ol \| CHEMBL2...) Show SMILES Cc1ccc2CCC(O)c2c1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	1.44E+6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Helsinki Curated by ChEMBL					Assay Description Non competitive inhibition of UGT2B17-catalyzed scopoletin glucuronidation				J Med Chem 49: 1818-27 (2006) Article DOI: 10.1021/jm051142c BindingDB Entry DOI: 10.7270/Q2B857QP
University of Helsinki Curated by ChEMBL					More data for this Ligand-Target Pair
Phosphatidylserine lipase ABHD16A (Homo sapiens (Human))	BDBM50507489 (CHEMBL4564841) Show SMILES COc1nn(-c2ccc(F)cc2)c(=O)o1 Show InChI	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	32	n/a	n/a	n/a	n/a	n/a	n/a
University of Helsinki Curated by ChEMBL					Assay Description Inhibition of ABHD16A (unknown origin)				ACS Med Chem Lett 9: 1269-1273 (2018) Article DOI: 10.1021/acsmedchemlett.8b00442 BindingDB Entry DOI: 10.7270/Q2KH0RM7
University of Helsinki Curated by ChEMBL					More data for this Ligand-Target Pair
UDP-glucuronosyltransferase 2B7 (Homo sapiens (Human))	BDBM50211740 ((1R)-phenyl-[(1R,2S,7S,8S,9S)-3,3,7-trimethyltricy...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	47	n/a	n/a	n/a	n/a	n/a	n/a
University of Helsinki Curated by ChEMBL					Assay Description Inhibition of human UGT2B7 by substrate-independent inhibition assay				J Med Chem 50: 2655-64 (2007) Article DOI: 10.1021/jm061204e BindingDB Entry DOI: 10.7270/Q23F4QF2
University of Helsinki Curated by ChEMBL					More data for this Ligand-Target Pair
UDP-glucuronosyltransferase 2B7 (Homo sapiens (Human))	BDBM50211740 ((1R)-phenyl-[(1R,2S,7S,8S,9S)-3,3,7-trimethyltricy...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	54	n/a	n/a	n/a	n/a	n/a	n/a
University of Helsinki Curated by ChEMBL					Assay Description Inhibition of human UGT2B7 assessed as reduction of estriol glucuronidation				J Med Chem 50: 2655-64 (2007) Article DOI: 10.1021/jm061204e BindingDB Entry DOI: 10.7270/Q23F4QF2
University of Helsinki Curated by ChEMBL					More data for this Ligand-Target Pair
Phosphatidylserine lipase ABHD16A (Homo sapiens (Human))	BDBM50336546 (CHEMBL1673415 \| Palmostatin B) Show SMILES Show InChI	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	57	n/a	n/a	n/a	n/a	n/a	n/a
University of Helsinki Curated by ChEMBL					Assay Description Reversible inhibition of human ABHD16A expressed in HEK293 cells preincubated for 30 mins followed by 40 fold compound dilution and subsequent 1-LG s...				ACS Med Chem Lett 9: 1269-1273 (2018) Article DOI: 10.1021/acsmedchemlett.8b00442 BindingDB Entry DOI: 10.7270/Q2KH0RM7
University of Helsinki Curated by ChEMBL					More data for this Ligand-Target Pair
Phosphatidylserine lipase ABHD16A (Homo sapiens (Human))	BDBM195603 (KC01) Show SMILES CCCCCCCCCCCCCC1OC(=O)\C1=C/CCCCC(N)=O Show InChI	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	90	n/a	n/a	n/a	n/a	n/a	n/a
University of Helsinki Curated by ChEMBL					Assay Description Inhibition of ABHD16A (unknown origin)				ACS Med Chem Lett 9: 1269-1273 (2018) Article DOI: 10.1021/acsmedchemlett.8b00442 BindingDB Entry DOI: 10.7270/Q2KH0RM7
University of Helsinki Curated by ChEMBL					More data for this Ligand-Target Pair
Phosphatidylserine lipase ABHD16A (Homo sapiens (Human))	BDBM50336546 (CHEMBL1673415 \| Palmostatin B) Show SMILES Show InChI	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	99	n/a	n/a	n/a	n/a	n/a	n/a
University of Helsinki Curated by ChEMBL					Assay Description Inhibition of human ABHD16A expressed in HEK293 cells preincubated for 30 mins followed by 1-LG substrate addition and measured after 90 to 120 mins ...				ACS Med Chem Lett 9: 1269-1273 (2018) Article DOI: 10.1021/acsmedchemlett.8b00442 BindingDB Entry DOI: 10.7270/Q2KH0RM7
University of Helsinki Curated by ChEMBL					More data for this Ligand-Target Pair
UDP-glucuronosyltransferase 2B7 (Homo sapiens (Human))	BDBM50211775 (((1S,3aR,4S,8aR,9S)-4,8,8-trimethyl-decahydro-1,4-...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
University of Helsinki Curated by ChEMBL					Assay Description Inhibition of human UGT2B7 assessed as reduction of estriol glucuronidation				J Med Chem 50: 2655-64 (2007) Article DOI: 10.1021/jm061204e BindingDB Entry DOI: 10.7270/Q23F4QF2
University of Helsinki Curated by ChEMBL					More data for this Ligand-Target Pair
Phosphatidylserine lipase ABHD16A (Homo sapiens (Human))	BDBM50336546 (CHEMBL1673415 \| Palmostatin B) Show SMILES Show InChI	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
University of Helsinki Curated by ChEMBL					Assay Description Inhibition of ABHD16A (unknown origin)				ACS Med Chem Lett 9: 1269-1273 (2018) Article DOI: 10.1021/acsmedchemlett.8b00442 BindingDB Entry DOI: 10.7270/Q2KH0RM7
University of Helsinki Curated by ChEMBL					More data for this Ligand-Target Pair
Phosphatidylserine lipase ABHD16A (Homo sapiens (Human))	BDBM24567 ((2S)-1-[(2S,3S)-3-hexyl-4-oxooxetan-2-yl]tridecan-...) Show SMILES Show InChI	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	170	n/a	n/a	n/a	n/a	n/a	n/a
University of Helsinki Curated by ChEMBL					Assay Description Inhibition of ABHD16A (unknown origin)				ACS Med Chem Lett 9: 1269-1273 (2018) Article DOI: 10.1021/acsmedchemlett.8b00442 BindingDB Entry DOI: 10.7270/Q2KH0RM7
University of Helsinki Curated by ChEMBL					More data for this Ligand-Target Pair
UDP-glucuronosyltransferase 2B7 (Homo sapiens (Human))	BDBM50211763 ((1R)-2-chloro-1-[(1R,2S,7S,8S,9S)-3,3,7-trimethylt...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
University of Helsinki Curated by ChEMBL					Assay Description Inhibition of human UGT2B7 assessed as reduction of estriol glucuronidation				J Med Chem 50: 2655-64 (2007) Article DOI: 10.1021/jm061204e BindingDB Entry DOI: 10.7270/Q23F4QF2
University of Helsinki Curated by ChEMBL					More data for this Ligand-Target Pair
UDP-glucuronosyltransferase 2B7 (Homo sapiens (Human))	BDBM50211780 ((1S)-2,2-dimethyl-1-[(1R,2S,7S,8S,9S)-3,3,7-trimet...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
University of Helsinki Curated by ChEMBL					Assay Description Inhibition of human UGT2B7 assessed as reduction of estriol glucuronidation				J Med Chem 50: 2655-64 (2007) Article DOI: 10.1021/jm061204e BindingDB Entry DOI: 10.7270/Q23F4QF2
University of Helsinki Curated by ChEMBL					More data for this Ligand-Target Pair
UDP-glucuronosyltransferase 2B7 (Homo sapiens (Human))	BDBM50211762 ((1S)-2-chloro-1-[(1R,2S,7S,8S,9S)-3,3,7-trimethylt...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
University of Helsinki Curated by ChEMBL					Assay Description Inhibition of human UGT2B7 assessed as reduction of estriol glucuronidation				J Med Chem 50: 2655-64 (2007) Article DOI: 10.1021/jm061204e BindingDB Entry DOI: 10.7270/Q23F4QF2
University of Helsinki Curated by ChEMBL					More data for this Ligand-Target Pair
UDP-glucuronosyltransferase 2B7 (Homo sapiens (Human))	BDBM50211777 ((1S)-1-[(1R,2S,7S,8S,9S)-3,3,7-trimethyltricyclo[5...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
University of Helsinki Curated by ChEMBL					Assay Description Inhibition of human UGT2B7 assessed as reduction of estriol glucuronidation				J Med Chem 50: 2655-64 (2007) Article DOI: 10.1021/jm061204e BindingDB Entry DOI: 10.7270/Q23F4QF2
University of Helsinki Curated by ChEMBL					More data for this Ligand-Target Pair

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