Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Sodium/potassium-transporting ATPase subunit alpha-4/beta-1 (Rattus norvegicus) | BDBM50255109![]() (CHEMBL4081196) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 0.00200 | n/a | n/a | n/a | n/a | n/a | n/a |
Department of Medicinal Chemistry and Institute for Therapeutics Discovery and Development, College of Pharmacy , University of Minnesota , Minneapolis , Minnesota 55414 , United States. Curated by ChEMBL | Assay Description Inhibition of recombinant rat Na+/K+-ATPase alpha4/beta1 expressed in baculovirus infected insect Sf9 cell membranes using [gamma-32P]ATP as substrat... | J Med Chem 61: 1800-1820 (2018) Article DOI: 10.1021/acs.jmedchem.7b00925 BindingDB Entry DOI: 10.7270/Q2T43WJH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium/potassium-transporting ATPase subunit alpha-4/beta-1 (Rattus norvegicus) | BDBM50255111![]() (CHEMBL4092961) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 0.0110 | n/a | n/a | n/a | n/a | n/a | n/a |
Department of Medicinal Chemistry and Institute for Therapeutics Discovery and Development, College of Pharmacy , University of Minnesota , Minneapolis , Minnesota 55414 , United States. Curated by ChEMBL | Assay Description Inhibition of recombinant rat Na+/K+-ATPase alpha4/beta1 expressed in baculovirus infected insect Sf9 cell membranes using [gamma-32P]ATP as substrat... | J Med Chem 61: 1800-1820 (2018) Article DOI: 10.1021/acs.jmedchem.7b00925 BindingDB Entry DOI: 10.7270/Q2T43WJH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium/potassium-transporting ATPase subunit alpha-4/beta-1 (Rattus norvegicus) | BDBM50255122![]() (CHEMBL4059538) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 0.600 | n/a | n/a | n/a | n/a | n/a | n/a |
Department of Medicinal Chemistry and Institute for Therapeutics Discovery and Development, College of Pharmacy , University of Minnesota , Minneapolis , Minnesota 55414 , United States. Curated by ChEMBL | Assay Description Inhibition of recombinant rat Na+/K+-ATPase alpha4/beta1 expressed in baculovirus infected insect Sf9 cell membranes using [gamma-32P]ATP as substrat... | J Med Chem 61: 1800-1820 (2018) Article DOI: 10.1021/acs.jmedchem.7b00925 BindingDB Entry DOI: 10.7270/Q2T43WJH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclin-A1/Cyclin-dependent kinase 2 (Homo sapiens (Human)) | BDBM2579![]() ((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet ![]() | Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 1.40 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of CDK2/Cyclin A1 (unknown origin) using histone H1 as substrate preincubated for 20 mins followed by 33P-ATP addition and measured after ... | Citation and Details Article DOI: 10.1016/j.ejmech.2021.113232 BindingDB Entry DOI: 10.7270/Q22J6GMW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium/potassium-transporting ATPase subunit alpha-4/beta-1 (Rattus norvegicus) | BDBM50255138![]() (CHEMBL4066361) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.40 | n/a | n/a | n/a | n/a | n/a | n/a |
Department of Medicinal Chemistry and Institute for Therapeutics Discovery and Development, College of Pharmacy , University of Minnesota , Minneapolis , Minnesota 55414 , United States. Curated by ChEMBL | Assay Description Inhibition of recombinant rat Na+/K+-ATPase alpha4/beta1 expressed in baculovirus infected insect Sf9 cell membranes using [gamma-32P]ATP as substrat... | J Med Chem 61: 1800-1820 (2018) Article DOI: 10.1021/acs.jmedchem.7b00925 BindingDB Entry DOI: 10.7270/Q2T43WJH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclin-O (Homo sapiens) | BDBM2579![]() ((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...) | UniProtKB/SwissProt GoogleScholar AffyNet ![]() | Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 1.5 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of CDK2/Cyclin-O (unknown origin) using histone H1 as substrate preincubated for 20 mins followed by 33P-ATP addition and measured after 2... | Citation and Details Article DOI: 10.1016/j.ejmech.2021.113232 BindingDB Entry DOI: 10.7270/Q22J6GMW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclin-dependent kinase 2/G1/S-specific cyclin-E1 (Homo sapiens (Human)) | BDBM2579![]() ((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet ![]() | Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 1.60 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of CDK2/Cyclin E (unknown origin) using histone H1 as substrate preincubated for 20 mins followed by 33P-ATP addition and measured after 2... | Citation and Details Article DOI: 10.1016/j.ejmech.2021.113232 BindingDB Entry DOI: 10.7270/Q22J6GMW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium/potassium-transporting ATPase subunit alpha-4/beta-3 (Rattus norvegicus) | BDBM50286739![]() (4-((1R,3S,5S,8R,10R,11R,13R,14S,17R)-1,5,11,14-tet...) | UniProtKB/SwissProt GoogleScholar AffyNet ![]() | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 1.80 | n/a | n/a | n/a | n/a | n/a | n/a |
Department of Medicinal Chemistry and Institute for Therapeutics Discovery and Development, College of Pharmacy , University of Minnesota , Minneapolis , Minnesota 55414 , United States. Curated by ChEMBL | Assay Description Inhibition of recombinant rat Na+/K+-ATPase alpha4/beta3 expressed in baculovirus infected Sf9 cell membranes using [gamma-32P]ATP as substrate prein... | J Med Chem 61: 1800-1820 (2018) Article DOI: 10.1021/acs.jmedchem.7b00925 BindingDB Entry DOI: 10.7270/Q2T43WJH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclin-dependent kinase 2/G1/S-specific cyclin-E1 (Homo sapiens (Human)) | BDBM50563174![]() (CHEMBL1708376) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 2.30 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of CDK2/Cyclin E (unknown origin) using histone H1 as substrate preincubated for 20 mins followed by 33P-ATP addition and measured after 2... | Citation and Details Article DOI: 10.1016/j.ejmech.2021.113232 BindingDB Entry DOI: 10.7270/Q22J6GMW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium/potassium-transporting ATPase subunit alpha-4/beta-1 (Rattus norvegicus) | BDBM50255120![]() (CHEBI:38178 | STROPHANTHIDIN) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | Purchase MCE PC cid PC sid UniChem | Article PubMed | n/a | n/a | 2.40 | n/a | n/a | n/a | n/a | n/a | n/a |
Department of Medicinal Chemistry and Institute for Therapeutics Discovery and Development, College of Pharmacy , University of Minnesota , Minneapolis , Minnesota 55414 , United States. Curated by ChEMBL | Assay Description Inhibition of recombinant rat Na+/K+-ATPase alpha4/beta1 expressed in baculovirus infected insect Sf9 cell membranes using [gamma-32P]ATP as substrat... | J Med Chem 61: 1800-1820 (2018) Article DOI: 10.1021/acs.jmedchem.7b00925 BindingDB Entry DOI: 10.7270/Q2T43WJH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Endothelin-1 receptor (RAT) | BDBM50064000![]() (CHEMBL3400988) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 3.30 | n/a | n/a | n/a | n/a | n/a | n/a |
Southeast University Curated by ChEMBL | Assay Description Displacement of PD156707 from rat ETA receptor after 1 hr by Lowry method | Bioorg Med Chem 23: 657-67 (2015) Article DOI: 10.1016/j.bmc.2015.01.003 BindingDB Entry DOI: 10.7270/Q28K7BRM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Endothelin-1 receptor (RAT) | BDBM50063998![]() (CHEMBL3400989) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 3.90 | n/a | n/a | n/a | n/a | n/a | n/a |
Southeast University Curated by ChEMBL | Assay Description Displacement of [125I]ET-1 from rat ETA receptor after 1 hr by Lowry method | Bioorg Med Chem 23: 657-67 (2015) Article DOI: 10.1016/j.bmc.2015.01.003 BindingDB Entry DOI: 10.7270/Q28K7BRM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium/potassium-transporting ATPase subunit alpha-4/beta-1 (Rattus norvegicus) | BDBM50255119![]() (CHEMBL4071710) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 4 | n/a | n/a | n/a | n/a | n/a | n/a |
Department of Medicinal Chemistry and Institute for Therapeutics Discovery and Development, College of Pharmacy , University of Minnesota , Minneapolis , Minnesota 55414 , United States. Curated by ChEMBL | Assay Description Inhibition of recombinant rat Na+/K+-ATPase alpha4/beta1 expressed in baculovirus infected insect Sf9 cell membranes using [gamma-32P]ATP as substrat... | J Med Chem 61: 1800-1820 (2018) Article DOI: 10.1021/acs.jmedchem.7b00925 BindingDB Entry DOI: 10.7270/Q2T43WJH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium/potassium-transporting ATPase subunit alpha-4/beta-1 (Rattus norvegicus) | BDBM50286739![]() (4-((1R,3S,5S,8R,10R,11R,13R,14S,17R)-1,5,11,14-tet...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | PDB Article PubMed | n/a | n/a | 4.30 | n/a | n/a | n/a | n/a | n/a | n/a |
Department of Medicinal Chemistry and Institute for Therapeutics Discovery and Development, College of Pharmacy , University of Minnesota , Minneapolis , Minnesota 55414 , United States. Curated by ChEMBL | Assay Description Inhibition of recombinant rat Na+/K+-ATPase alpha4/beta1 expressed in baculovirus infected insect Sf9 cell membranes using [gamma-32P]ATP as substrat... | J Med Chem 61: 1800-1820 (2018) Article DOI: 10.1021/acs.jmedchem.7b00925 BindingDB Entry DOI: 10.7270/Q2T43WJH | |||||||||||
More data for this Ligand-Target Pair | ![]() 3D Structure (crystal) | ||||||||||||
Endothelin-1 receptor (RAT) | BDBM50061101![]() (4-(1,1-Dimethylethyl)-N-(6-(2-hydroxyethoxy)-5-(2-...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet ![]() | Purchase CHEMBL DrugBank MCE PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 4.70 | n/a | n/a | n/a | n/a | n/a | n/a |
Southeast University Curated by ChEMBL | Assay Description Displacement of [125I]ET-1 from rat ETA receptor after 1 hr by Lowry method | Bioorg Med Chem 23: 657-67 (2015) Article DOI: 10.1016/j.bmc.2015.01.003 BindingDB Entry DOI: 10.7270/Q28K7BRM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium/potassium-transporting ATPase subunit alpha-4/beta-1 (Rattus norvegicus) | BDBM50255140![]() (CHEMBL4076623) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 4.90 | n/a | n/a | n/a | n/a | n/a | n/a |
Department of Medicinal Chemistry and Institute for Therapeutics Discovery and Development, College of Pharmacy , University of Minnesota , Minneapolis , Minnesota 55414 , United States. Curated by ChEMBL | Assay Description Inhibition of recombinant rat Na+/K+-ATPase alpha4/beta1 expressed in baculovirus infected insect Sf9 cell membranes using [gamma-32P]ATP as substrat... | J Med Chem 61: 1800-1820 (2018) Article DOI: 10.1021/acs.jmedchem.7b00925 BindingDB Entry DOI: 10.7270/Q2T43WJH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium/potassium-transporting ATPase subunit alpha-4/beta-1 (Rattus norvegicus) | BDBM50255139![]() (CHEMBL4085219) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 5 | n/a | n/a | n/a | n/a | n/a | n/a |
Department of Medicinal Chemistry and Institute for Therapeutics Discovery and Development, College of Pharmacy , University of Minnesota , Minneapolis , Minnesota 55414 , United States. Curated by ChEMBL | Assay Description Inhibition of recombinant rat Na+/K+-ATPase alpha4/beta1 expressed in baculovirus infected insect Sf9 cell membranes using [gamma-32P]ATP as substrat... | J Med Chem 61: 1800-1820 (2018) Article DOI: 10.1021/acs.jmedchem.7b00925 BindingDB Entry DOI: 10.7270/Q2T43WJH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium/potassium-transporting ATPase subunit alpha-4/beta-1 (Rattus norvegicus) | BDBM46355![]() (DIGOXIN | MLS000069819 | SMR000059217 | US10668094...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | Purchase DrugBank KEGG PC cid PC sid PDB UniChem Patents Similars | PDB Article PubMed | n/a | n/a | 5.5 | n/a | n/a | n/a | n/a | n/a | n/a |
Department of Medicinal Chemistry and Institute for Therapeutics Discovery and Development, College of Pharmacy , University of Minnesota , Minneapolis , Minnesota 55414 , United States. Curated by ChEMBL | Assay Description Inhibition of recombinant rat Na+/K+-ATPase alpha4/beta1 expressed in baculovirus infected insect Sf9 cell membranes using [gamma-32P]ATP as substrat... | J Med Chem 61: 1800-1820 (2018) Article DOI: 10.1021/acs.jmedchem.7b00925 BindingDB Entry DOI: 10.7270/Q2T43WJH | |||||||||||
More data for this Ligand-Target Pair | ![]() 3D Structure (crystal) | ||||||||||||
Endothelin-1 receptor (RAT) | BDBM50063997![]() (CHEMBL3400996) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 5.5 | n/a | n/a | n/a | n/a | n/a | n/a |
Southeast University Curated by ChEMBL | Assay Description Displacement of [125I]ET-1 from rat ETA receptor after 1 hr by Lowry method | Bioorg Med Chem 23: 657-67 (2015) Article DOI: 10.1016/j.bmc.2015.01.003 BindingDB Entry DOI: 10.7270/Q28K7BRM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dipeptidyl peptidase 4 (Homo sapiens (Human)) | BDBM11162![]() ((1R)-3-oxo-3-[3-(trifluoroethyl)-5,6-dihydro[1,2,4...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | Purchase CHEMBL DrugBank MCE PC cid PC sid PDB UniChem Similars | DrugBank PDB Article PubMed | n/a | n/a | 7.80 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of recombinant human DPP4 using Gly-Pro-AMC as substrate incubated for 1 hr by fluorogenic assay | Citation and Details Article DOI: 10.1016/j.bmc.2020.115861 BindingDB Entry DOI: 10.7270/Q2930XTC | |||||||||||
More data for this Ligand-Target Pair | ![]() 3D Structure (crystal) | ||||||||||||
Cyclin-dependent kinase 2/G1/S-specific cyclin-E1 (Homo sapiens (Human)) | BDBM50563177![]() (CHEMBL4763182) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 8.90 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of CDK2/Cyclin E (unknown origin) using histone H1 as substrate preincubated for 20 mins followed by 33P-ATP addition and measured after 2... | Citation and Details Article DOI: 10.1016/j.ejmech.2021.113232 BindingDB Entry DOI: 10.7270/Q22J6GMW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium/potassium-transporting ATPase subunit alpha-4/beta-1 (Rattus norvegicus) | BDBM50255128![]() (CHEMBL4067657) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 10 | n/a | n/a | n/a | n/a | n/a | n/a |
Department of Medicinal Chemistry and Institute for Therapeutics Discovery and Development, College of Pharmacy , University of Minnesota , Minneapolis , Minnesota 55414 , United States. Curated by ChEMBL | Assay Description Inhibition of recombinant rat Na+/K+-ATPase alpha4/beta1 expressed in baculovirus infected insect Sf9 cell membranes using [gamma-32P]ATP as substrat... | J Med Chem 61: 1800-1820 (2018) Article DOI: 10.1021/acs.jmedchem.7b00925 BindingDB Entry DOI: 10.7270/Q2T43WJH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium/potassium-transporting ATPase subunit alpha-4/beta-1 (Rattus norvegicus) | BDBM50255117![]() (CHEMBL4072996) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 12 | n/a | n/a | n/a | n/a | n/a | n/a |
Department of Medicinal Chemistry and Institute for Therapeutics Discovery and Development, College of Pharmacy , University of Minnesota , Minneapolis , Minnesota 55414 , United States. Curated by ChEMBL | Assay Description Inhibition of recombinant rat Na+/K+-ATPase alpha4/beta1 expressed in baculovirus infected insect Sf9 cell membranes using [gamma-32P]ATP as substrat... | J Med Chem 61: 1800-1820 (2018) Article DOI: 10.1021/acs.jmedchem.7b00925 BindingDB Entry DOI: 10.7270/Q2T43WJH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium/potassium-transporting ATPase subunit alpha-4/beta-1 (Rattus norvegicus) | BDBM50255121![]() (CHEBI:4037 | CHEMBL1075788) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | Purchase MCE KEGG PC cid PC sid UniChem | Article PubMed | n/a | n/a | 12 | n/a | n/a | n/a | n/a | n/a | n/a |
Department of Medicinal Chemistry and Institute for Therapeutics Discovery and Development, College of Pharmacy , University of Minnesota , Minneapolis , Minnesota 55414 , United States. Curated by ChEMBL | Assay Description Inhibition of recombinant rat Na+/K+-ATPase alpha4/beta1 expressed in baculovirus infected insect Sf9 cell membranes using [gamma-32P]ATP as substrat... | J Med Chem 61: 1800-1820 (2018) Article DOI: 10.1021/acs.jmedchem.7b00925 BindingDB Entry DOI: 10.7270/Q2T43WJH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Endothelin-1 receptor (RAT) | BDBM50063999![]() (CHEMBL3400984) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 12 | n/a | n/a | n/a | n/a | n/a | n/a |
Southeast University Curated by ChEMBL | Assay Description Displacement of [125I]ET-1 from rat ETA receptor after 1 hr by Lowry method | Bioorg Med Chem 23: 657-67 (2015) Article DOI: 10.1016/j.bmc.2015.01.003 BindingDB Entry DOI: 10.7270/Q28K7BRM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium/potassium-transporting ATPase subunit alpha-4/beta-1 (Rattus norvegicus) | BDBM50255116![]() (CHEMBL4074239) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 13 | n/a | n/a | n/a | n/a | n/a | n/a |
Department of Medicinal Chemistry and Institute for Therapeutics Discovery and Development, College of Pharmacy , University of Minnesota , Minneapolis , Minnesota 55414 , United States. Curated by ChEMBL | Assay Description Inhibition of recombinant rat Na+/K+-ATPase alpha4/beta1 expressed in baculovirus infected insect Sf9 cell membranes using [gamma-32P]ATP as substrat... | J Med Chem 61: 1800-1820 (2018) Article DOI: 10.1021/acs.jmedchem.7b00925 BindingDB Entry DOI: 10.7270/Q2T43WJH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dipeptidyl peptidase 4 (Homo sapiens (Human)) | BDBM50462415![]() (CHEMBL4250492) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 14 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of recombinant human DPP4 using Gly-Pro-AMC as substrate incubated for 1 hr by fluorogenic assay | Citation and Details Article DOI: 10.1016/j.bmc.2020.115861 BindingDB Entry DOI: 10.7270/Q2930XTC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Endothelin-1 receptor (RAT) | BDBM50063996![]() (CHEMBL3400998) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 19 | n/a | n/a | n/a | n/a | n/a | n/a |
Southeast University Curated by ChEMBL | Assay Description Displacement of [125I]ET-1 from rat ETA receptor after 1 hr by Lowry method | Bioorg Med Chem 23: 657-67 (2015) Article DOI: 10.1016/j.bmc.2015.01.003 BindingDB Entry DOI: 10.7270/Q28K7BRM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclin-A1/Cyclin-dependent kinase 2 (Homo sapiens (Human)) | BDBM50563174![]() (CHEMBL1708376) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 24 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of CDK2/Cyclin A1 (unknown origin) using histone H1 as substrate preincubated for 20 mins followed by 33P-ATP addition and measured after ... | Citation and Details Article DOI: 10.1016/j.ejmech.2021.113232 BindingDB Entry DOI: 10.7270/Q22J6GMW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclin-dependent kinase 2/G1/S-specific cyclin-E1 (Homo sapiens (Human)) | BDBM50563140![]() (CHEMBL1906448) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 27 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of CDK2/Cyclin E (unknown origin) using histone H1 as substrate preincubated for 20 mins followed by 33P-ATP addition and measured after 2... | Citation and Details Article DOI: 10.1016/j.ejmech.2021.113232 BindingDB Entry DOI: 10.7270/Q22J6GMW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dipeptidyl peptidase 4 (Homo sapiens (Human)) | BDBM50552244![]() (CHEMBL4790735) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 28 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of recombinant human DPP4 using Gly-Pro-AMC as substrate incubated for 1 hr by fluorogenic assay | Citation and Details Article DOI: 10.1016/j.bmc.2020.115861 BindingDB Entry DOI: 10.7270/Q2930XTC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Endothelin-1 receptor (RAT) | BDBM50029352![]() (CHEMBL336033 | [(5S,8S,11R,14S,16aR)-8-(1H-Indol-3...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet ![]() | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 28 | n/a | n/a | n/a | n/a | n/a | n/a |
Southeast University Curated by ChEMBL | Assay Description Displacement of [125I]ET-1 from rat ETA receptor after 1 hr by Lowry method | Bioorg Med Chem 23: 657-67 (2015) Article DOI: 10.1016/j.bmc.2015.01.003 BindingDB Entry DOI: 10.7270/Q28K7BRM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium/potassium-transporting ATPase subunit alpha-3/beta-1 (Rattus norvegicus) | BDBM50286739![]() (4-((1R,3S,5S,8R,10R,11R,13R,14S,17R)-1,5,11,14-tet...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | PDB Article PubMed | n/a | n/a | 31 | n/a | n/a | n/a | n/a | n/a | n/a |
Department of Medicinal Chemistry and Institute for Therapeutics Discovery and Development, College of Pharmacy , University of Minnesota , Minneapolis , Minnesota 55414 , United States. Curated by ChEMBL | Assay Description Inhibition of recombinant rat Na+/K+-ATPase alpha3/beta1 expressed in baculovirus infected insect Sf9 cell membranes using [gamma-32P]ATP as substrat... | J Med Chem 61: 1800-1820 (2018) Article DOI: 10.1021/acs.jmedchem.7b00925 BindingDB Entry DOI: 10.7270/Q2T43WJH | |||||||||||
More data for this Ligand-Target Pair | ![]() 3D Structure (crystal) | ||||||||||||
Sodium/potassium-transporting ATPase subunit alpha-4/beta-1 (Rattus norvegicus) | BDBM50255108![]() (CHEMBL4077606) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 32 | n/a | n/a | n/a | n/a | n/a | n/a |
Department of Medicinal Chemistry and Institute for Therapeutics Discovery and Development, College of Pharmacy , University of Minnesota , Minneapolis , Minnesota 55414 , United States. Curated by ChEMBL | Assay Description Inhibition of recombinant rat Na+/K+-ATPase alpha4/beta1 expressed in baculovirus infected insect Sf9 cell membranes using [gamma-32P]ATP as substrat... | J Med Chem 61: 1800-1820 (2018) Article DOI: 10.1021/acs.jmedchem.7b00925 BindingDB Entry DOI: 10.7270/Q2T43WJH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium/potassium-transporting ATPase subunit alpha-4/beta-1 (Rattus norvegicus) | BDBM50255107![]() (CHEMBL4093925) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 32 | n/a | n/a | n/a | n/a | n/a | n/a |
Department of Medicinal Chemistry and Institute for Therapeutics Discovery and Development, College of Pharmacy , University of Minnesota , Minneapolis , Minnesota 55414 , United States. Curated by ChEMBL | Assay Description Inhibition of recombinant rat Na+/K+-ATPase alpha4/beta1 expressed in baculovirus infected insect Sf9 cell membranes using [gamma-32P]ATP as substrat... | J Med Chem 61: 1800-1820 (2018) Article DOI: 10.1021/acs.jmedchem.7b00925 BindingDB Entry DOI: 10.7270/Q2T43WJH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium/potassium-transporting ATPase subunit alpha-4/beta-1 (Rattus norvegicus) | BDBM50255114![]() (CHEMBL4072200) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 33 | n/a | n/a | n/a | n/a | n/a | n/a |
Department of Medicinal Chemistry and Institute for Therapeutics Discovery and Development, College of Pharmacy , University of Minnesota , Minneapolis , Minnesota 55414 , United States. Curated by ChEMBL | Assay Description Inhibition of recombinant rat Na+/K+-ATPase alpha4/beta1 expressed in baculovirus infected insect Sf9 cell membranes using [gamma-32P]ATP as substrat... | J Med Chem 61: 1800-1820 (2018) Article DOI: 10.1021/acs.jmedchem.7b00925 BindingDB Entry DOI: 10.7270/Q2T43WJH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclin-O (Homo sapiens) | BDBM50563174![]() (CHEMBL1708376) | UniProtKB/SwissProt GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 33 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of CDK2/Cyclin-O (unknown origin) using histone H1 as substrate preincubated for 20 mins followed by 33P-ATP addition and measured after 2... | Citation and Details Article DOI: 10.1016/j.ejmech.2021.113232 BindingDB Entry DOI: 10.7270/Q22J6GMW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium/potassium-transporting ATPase subunit alpha-4/beta-1 (Rattus norvegicus) | BDBM50255127![]() (CHEMBL4095064) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 39 | n/a | n/a | n/a | n/a | n/a | n/a |
Department of Medicinal Chemistry and Institute for Therapeutics Discovery and Development, College of Pharmacy , University of Minnesota , Minneapolis , Minnesota 55414 , United States. Curated by ChEMBL | Assay Description Inhibition of recombinant rat Na+/K+-ATPase alpha4/beta1 expressed in baculovirus infected insect Sf9 cell membranes using [gamma-32P]ATP as substrat... | J Med Chem 61: 1800-1820 (2018) Article DOI: 10.1021/acs.jmedchem.7b00925 BindingDB Entry DOI: 10.7270/Q2T43WJH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclin-O (Homo sapiens) | BDBM50563177![]() (CHEMBL4763182) | UniProtKB/SwissProt GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 42 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of CDK2/Cyclin-O (unknown origin) using histone H1 as substrate preincubated for 20 mins followed by 33P-ATP addition and measured after 2... | Citation and Details Article DOI: 10.1016/j.ejmech.2021.113232 BindingDB Entry DOI: 10.7270/Q22J6GMW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclin-A1/Cyclin-dependent kinase 2 (Homo sapiens (Human)) | BDBM50563177![]() (CHEMBL4763182) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 46 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of CDK2/Cyclin A1 (unknown origin) using histone H1 as substrate preincubated for 20 mins followed by 33P-ATP addition and measured after ... | Citation and Details Article DOI: 10.1016/j.ejmech.2021.113232 BindingDB Entry DOI: 10.7270/Q22J6GMW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Histone deacetylase 1 (Homo sapiens (Human)) | BDBM50082211![]() (CHEMBL3421742) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 60 | n/a | n/a | n/a | n/a | n/a | n/a |
Southeast University Curated by ChEMBL | Assay Description Inhibition of recombinant HDAC1 (unknown origin) using fluorogenic substrate Boc-Lys (acetyl)-AMC after 20 mins by homogeneous fluorescence release a... | Eur J Med Chem 96: 1-13 (2015) Article DOI: 10.1016/j.ejmech.2015.04.002 BindingDB Entry DOI: 10.7270/Q21G0P01 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Aurora kinase A (Homo sapiens (Human)) | BDBM50029422![]() (CHEMBL3343311) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 61 | n/a | n/a | n/a | n/a | n/a | n/a |
Southeast University Curated by ChEMBL | Assay Description Inhibition of Aurora-A (unknown origin) using STK substrate 2-biotin by HTRF-KinEASE-STK assay | Bioorg Med Chem 22: 5813-23 (2014) Article DOI: 10.1016/j.bmc.2014.09.029 BindingDB Entry DOI: 10.7270/Q279468G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Histone deacetylase 1 (Homo sapiens (Human)) | BDBM50094049![]() (CHEMBL3585965) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 70 | n/a | n/a | n/a | n/a | n/a | n/a |
Southeast University Curated by ChEMBL | Assay Description Inhibition of recombinant HDAC1 (unknown origin) incubated for 10 mins using Boc-Lys(acetyl)-AMC fluorogenic substrate by homogeneous fluorescence re... | Bioorg Med Chem 23: 3457-71 (2015) Article DOI: 10.1016/j.bmc.2015.04.028 BindingDB Entry DOI: 10.7270/Q2W95BXX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Histone deacetylase 1 (Homo sapiens (Human)) | BDBM50082261![]() (CHEMBL3421746) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 70 | n/a | n/a | n/a | n/a | n/a | n/a |
Southeast University Curated by ChEMBL | Assay Description Inhibition of recombinant HDAC1 (unknown origin) using fluorogenic substrate Boc-Lys (acetyl)-AMC after 20 mins by homogeneous fluorescence release a... | Eur J Med Chem 96: 1-13 (2015) Article DOI: 10.1016/j.ejmech.2015.04.002 BindingDB Entry DOI: 10.7270/Q21G0P01 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Aurora kinase A (Homo sapiens (Human)) | BDBM50029416![]() (CHEMBL3343310) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 78 | n/a | n/a | n/a | n/a | n/a | n/a |
Southeast University Curated by ChEMBL | Assay Description Inhibition of Aurora-A (unknown origin) using STK substrate 2-biotin by HTRF-KinEASE-STK assay | Bioorg Med Chem 22: 5813-23 (2014) Article DOI: 10.1016/j.bmc.2014.09.029 BindingDB Entry DOI: 10.7270/Q279468G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Histone deacetylase 1 (Homo sapiens (Human)) | BDBM50094054![]() (CHEMBL3585968) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 80 | n/a | n/a | n/a | n/a | n/a | n/a |
Southeast University Curated by ChEMBL | Assay Description Inhibition of recombinant HDAC1 (unknown origin) incubated for 10 mins using Boc-Lys(acetyl)-AMC fluorogenic substrate by homogeneous fluorescence re... | Bioorg Med Chem 23: 3457-71 (2015) Article DOI: 10.1016/j.bmc.2015.04.028 BindingDB Entry DOI: 10.7270/Q2W95BXX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Aurora kinase A (Homo sapiens (Human)) | BDBM50029449![]() (CHEMBL3343321) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 82 | n/a | n/a | n/a | n/a | n/a | n/a |
Southeast University Curated by ChEMBL | Assay Description Inhibition of Aurora-A (unknown origin) using STK substrate 2-biotin by HTRF-KinEASE-STK assay | Bioorg Med Chem 22: 5813-23 (2014) Article DOI: 10.1016/j.bmc.2014.09.029 BindingDB Entry DOI: 10.7270/Q279468G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Histone deacetylase 1 (Homo sapiens (Human)) | BDBM50082210![]() (CHEMBL3421741) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 90 | n/a | n/a | n/a | n/a | n/a | n/a |
Southeast University Curated by ChEMBL | Assay Description Inhibition of recombinant HDAC1 (unknown origin) using fluorogenic substrate Boc-Lys (acetyl)-AMC after 20 mins by homogeneous fluorescence release a... | Eur J Med Chem 96: 1-13 (2015) Article DOI: 10.1016/j.ejmech.2015.04.002 BindingDB Entry DOI: 10.7270/Q21G0P01 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cholinesterase (Equus caballus (Horse)) | BDBM50559361![]() (CHEMBL4782213) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 90 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of equine serum BuChE using butyrylthiocholine iodide as substrate preincubated for 5 mins followed by substrate addition and measured aft... | Citation and Details Article DOI: 10.1016/j.bmcl.2020.127756 BindingDB Entry DOI: 10.7270/Q2CF9TS5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Endothelin receptor type B (RAT) | BDBM50061101![]() (4-(1,1-Dimethylethyl)-N-(6-(2-hydroxyethoxy)-5-(2-...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet ![]() | Purchase CHEMBL DrugBank MCE PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 95 | n/a | n/a | n/a | n/a | n/a | n/a |
Southeast University Curated by ChEMBL | Assay Description Displacement of [125I]ET-1 from rat ETB receptor after 1 hr by Lowry method | Bioorg Med Chem 23: 657-67 (2015) Article DOI: 10.1016/j.bmc.2015.01.003 BindingDB Entry DOI: 10.7270/Q28K7BRM | |||||||||||
More data for this Ligand-Target Pair |
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