Compile Data Set for Download or QSAR

Found 69 hits with Last Name = 'sliedregt' and Initial = 'la'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Asialoglycoprotein receptor 1 (Mus musculus)	BDBM50074090 (CHEMBL2368210 | Galactoside analogue) Show SMILES OC[C@@H]1O[C@@H](OCCCCC(=O)NCCCNC(=O)CCOCC(COCCC(=O)NCCCNC(=O)CCCCO[C@@H]2O[C@@H](CO)[C@H](O)[C@H](O)[C@@H]2O)(COCCC(=O)NCCCNC(=O)CCCCO[C@@H]2O[C@@H](CO)[C@H](O)[C@H](O)[C@@H]2O)NC(=O)CNC(=O)OCc2ccccc2)[C@@H](O)[C@@H](O)[C@H]1O Show InChI InChI=1S/C65H110N8O30/c74-34-42-52(84)55(87)58(90)61(101-42)97-27-7-4-15-45(77)66-21-10-24-69-48(80)18-30-94-38-65(73-51(83)33-72-64(93)100-37-41-13-2-1-3-14-41,39-95-31-19-49(81)70-25-11-22-67-46(78)16-5-8-28-98-62-59(91)56(88)53(85)43(35-75)102-62)40-96-32-20-50(82)71-26-12-23-68-47(79)17-6-9-29-99-63-60(92)57(89)54(86)44(36-76)103-63/h1-3,13-14,42-44,52-63,74-76,84-92H,4-12,15-40H2,(H,66,77)(H,67,78)(H,68,79)(H,69,80)(H,70,81)(H,71,82)(H,72,93)(H,73,83)/t42?,43?,44?,52-,53-,54-,55?,56?,57?,58?,59?,60?,61?,62?,63?,65?/m1/s1	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	93	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Leiden University Curated by ChEMBL					Assay Description Affinity tested by in vitro competition assay of [125I]ASOR binding to parenchymal rat liver cells				J Med Chem 42: 609-18 (1999) Article DOI: 10.1021/jm981078h BindingDB Entry DOI: 10.7270/Q2BR8RCC
					More data for this Ligand-Target Pair
Asialoglycoprotein receptor 1 (Mus musculus)	BDBM50074091 (CHEMBL2368208 | Galactoside analogue) Show SMILES OC[C@@H]1O[C@@H](OCCCCC(=O)NCC(=O)NCCCC(=O)OCC(COC(=O)CCCNC(=O)CNC(=O)CCCCO[C@@H]2O[C@@H](CO)[C@H](O)[C@H](O)[C@@H]2O)(COC(=O)CCCNC(=O)CNC(=O)CCCCO[C@@H]2O[C@@H](CO)[C@H](O)[C@H](O)[C@@H]2O)NC(=O)CNC(=O)OCc2ccccc2)[C@@H](O)[C@@H](O)[C@H]1O Show InChI InChI=1S/C65H104N8O33/c74-31-39-52(87)55(90)58(93)61(104-39)97-24-7-4-15-42(77)69-27-45(80)66-21-10-18-49(84)101-35-65(73-48(83)30-72-64(96)100-34-38-13-2-1-3-14-38,36-102-50(85)19-11-22-67-46(81)28-70-43(78)16-5-8-25-98-62-59(94)56(91)53(88)40(32-75)105-62)37-103-51(86)20-12-23-68-47(82)29-71-44(79)17-6-9-26-99-63-60(95)57(92)54(89)41(33-76)106-63/h1-3,13-14,39-41,52-63,74-76,87-95H,4-12,15-37H2,(H,66,80)(H,67,81)(H,68,82)(H,69,77)(H,70,78)(H,71,79)(H,72,96)(H,73,83)/t39?,40?,41?,52-,53-,54-,55?,56?,57?,58?,59?,60?,61?,62?,63?,65?/m1/s1	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	93	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Leiden University Curated by ChEMBL					Assay Description Affinity tested by in vitro competition assay of [125I]ASOR binding to parenchymal rat liver cells				J Med Chem 42: 609-18 (1999) Article DOI: 10.1021/jm981078h BindingDB Entry DOI: 10.7270/Q2BR8RCC
					More data for this Ligand-Target Pair
Asialoglycoprotein receptor 1 (Mus musculus)	BDBM50074089 (CHEMBL2368207 | TG(20)C-Galactoside analogue) Show SMILES [H][C@@]12CC[C@H](C(C)CCCC(C)C)[C@@]1(C)CC[C@@]1([H])[C@@]2([H])CC=C2C[C@H](CC[C@]12C)OC(=O)CNC(=O)CCCCC(=O)NCC(=O)NC(COCOCCOCCOCCOCCO[C@@H]1O[C@@H](CO)[C@H](O)[C@H](O)[C@@H]1O)(COCOCCOCCOCCOCCO[C@@H]1O[C@@H](CO)[C@H](O)[C@H](O)[C@@H]1O)COCOCCOCCOCCOCCO[C@@H]1O[C@@H](CO)[C@H](O)[C@H](O)[C@@H]1O |t:24| Show InChI InChI=1S/C86H153N3O38/c1-57(2)9-8-10-58(3)62-15-16-63-61-14-13-59-45-60(17-19-84(59,4)64(61)18-20-85(62,63)5)124-71(96)47-88-69(94)12-7-6-11-68(93)87-46-70(95)89-86(51-118-54-115-36-33-109-24-21-106-27-30-112-39-42-121-81-78(103)75(100)72(97)65(48-90)125-81,52-119-55-116-37-34-110-25-22-107-28-31-113-40-43-122-82-79(104)76(101)73(98)66(49-91)126-82)53-120-56-117-38-35-111-26-23-108-29-32-114-41-44-123-83-80(105)77(102)74(99)67(50-92)127-83/h13,57-58,60-67,72-83,90-92,97-105H,6-12,14-56H2,1-5H3,(H,87,93)(H,88,94)(H,89,95)/t58?,60-,61?,62+,63?,64?,65?,66?,67?,72+,73+,74+,75?,76?,77?,78?,79?,80?,81?,82?,83?,84-,85+,86?/m0/s1	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	200	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Leiden University Curated by ChEMBL					Assay Description Affinity tested by in vitro competition assay of [125I]ASOR binding to parenchymal rat liver cells				J Med Chem 42: 609-18 (1999) Article DOI: 10.1021/jm981078h BindingDB Entry DOI: 10.7270/Q2BR8RCC
					More data for this Ligand-Target Pair
Sphingosine 1-phosphate receptor 5 (Homo sapiens (Human))	BDBM195889 (US9670220, 33) Show SMILES OC(=O)CCN1CCc2oc(cc2C1)-c1ccc(OCc2ccccc2F)cc1 Show InChI InChI=1S/C23H22FNO4/c24-20-4-2-1-3-17(20)15-28-19-7-5-16(6-8-19)22-13-18-14-25(12-10-23(26)27)11-9-21(18)29-22/h1-8,13H,9-12,14-15H2,(H,26,27)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	16	n/a	n/a	n/a	n/a
Abbvie B.V.; AbbiVie Inc. US Patent					Assay Description The CHO-human-S1P5-Aeqorin assay was bought from Euroscreen, Brussels (Euroscreen, Technical dossier, Human Lysophospholid S1P5 (Edg8) receptor, DNA ...				US Patent US9670220 (2017) BindingDB Entry DOI: 10.7270/Q2QJ7FHD
					More data for this Ligand-Target Pair
Sphingosine 1-phosphate receptor 1 (Homo sapiens (Human))	BDBM195889 (US9670220, 33) Show SMILES OC(=O)CCN1CCc2oc(cc2C1)-c1ccc(OCc2ccccc2F)cc1 Show InChI InChI=1S/C23H22FNO4/c24-20-4-2-1-3-17(20)15-28-19-7-5-16(6-8-19)22-13-18-14-25(12-10-23(26)27)11-9-21(18)29-22/h1-8,13H,9-12,14-15H2,(H,26,27)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	100	n/a	n/a	n/a	25
Abbvie B.V.; AbbiVie Inc. US Patent					Assay Description The CHO-K1-Human S1P1-c-AMP assay was performed at Euroscreenfast, Brussels (Euroscreen, Human S1P1 coupling Gi/0, (Edg1) receptor, catalog no: FAST-...				US Patent US9670220 (2017) BindingDB Entry DOI: 10.7270/Q2QJ7FHD
					More data for this Ligand-Target Pair
Sphingosine 1-phosphate receptor 3 (Homo sapiens (Human))	BDBM195889 (US9670220, 33) Show SMILES OC(=O)CCN1CCc2oc(cc2C1)-c1ccc(OCc2ccccc2F)cc1 Show InChI InChI=1S/C23H22FNO4/c24-20-4-2-1-3-17(20)15-28-19-7-5-16(6-8-19)22-13-18-14-25(12-10-23(26)27)11-9-21(18)29-22/h1-8,13H,9-12,14-15H2,(H,26,27)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	3.20E+3	n/a	n/a	n/a	n/a
Abbvie B.V.; AbbiVie Inc. US Patent					Assay Description The CHO-human-S1P3-Aeqorin assay (CHO/Gα16/AEQ/h-S1P3) was established at Solvay Pharmaceuticals. The plasmid DNA coding for the S1P3 receptor (...				US Patent US9670220 (2017) BindingDB Entry DOI: 10.7270/Q2QJ7FHD
					More data for this Ligand-Target Pair
Sphingosine 1-phosphate receptor 5 (Homo sapiens (Human))	BDBM195890 (US9670220, 35) Show SMILES OC(=O)CCCN1CCc2oc(cc2C1)-c1ccc(OCc2ccccc2F)cc1 Show InChI InChI=1S/C24H24FNO4/c25-21-5-2-1-4-18(21)16-29-20-9-7-17(8-10-20)23-14-19-15-26(12-3-6-24(27)28)13-11-22(19)30-23/h1-2,4-5,7-10,14H,3,6,11-13,15-16H2,(H,27,28)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	5	n/a	n/a	n/a	n/a
Abbvie B.V.; AbbiVie Inc. US Patent					Assay Description The CHO-human-S1P5-Aeqorin assay was bought from Euroscreen, Brussels (Euroscreen, Technical dossier, Human Lysophospholid S1P5 (Edg8) receptor, DNA ...				US Patent US9670220 (2017) BindingDB Entry DOI: 10.7270/Q2QJ7FHD
					More data for this Ligand-Target Pair
Sphingosine 1-phosphate receptor 1 (Homo sapiens (Human))	BDBM195890 (US9670220, 35) Show SMILES OC(=O)CCCN1CCc2oc(cc2C1)-c1ccc(OCc2ccccc2F)cc1 Show InChI InChI=1S/C24H24FNO4/c25-21-5-2-1-4-18(21)16-29-20-9-7-17(8-10-20)23-14-19-15-26(12-3-6-24(27)28)13-11-22(19)30-23/h1-2,4-5,7-10,14H,3,6,11-13,15-16H2,(H,27,28)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	250	n/a	n/a	n/a	25
Abbvie B.V.; AbbiVie Inc. US Patent					Assay Description The CHO-K1-Human S1P1-c-AMP assay was performed at Euroscreenfast, Brussels (Euroscreen, Human S1P1 coupling Gi/0, (Edg1) receptor, catalog no: FAST-...				US Patent US9670220 (2017) BindingDB Entry DOI: 10.7270/Q2QJ7FHD
					More data for this Ligand-Target Pair
Sphingosine 1-phosphate receptor 3 (Homo sapiens (Human))	BDBM195890 (US9670220, 35) Show SMILES OC(=O)CCCN1CCc2oc(cc2C1)-c1ccc(OCc2ccccc2F)cc1 Show InChI InChI=1S/C24H24FNO4/c25-21-5-2-1-4-18(21)16-29-20-9-7-17(8-10-20)23-14-19-15-26(12-3-6-24(27)28)13-11-22(19)30-23/h1-2,4-5,7-10,14H,3,6,11-13,15-16H2,(H,27,28)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	5.00E+3	n/a	n/a	n/a	n/a
Abbvie B.V.; AbbiVie Inc. US Patent					Assay Description The CHO-human-S1P3-Aeqorin assay (CHO/Gα16/AEQ/h-S1P3) was established at Solvay Pharmaceuticals. The plasmid DNA coding for the S1P3 receptor (...				US Patent US9670220 (2017) BindingDB Entry DOI: 10.7270/Q2QJ7FHD
					More data for this Ligand-Target Pair
Sphingosine 1-phosphate receptor 5 (Homo sapiens (Human))	BDBM195892 (US9670220, 47) Show SMILES OC(=O)CCN1CCc2oc(nc2C1)-c1ccc(OCc2ccccc2F)cc1 Show InChI InChI=1S/C22H21FN2O4/c23-18-4-2-1-3-16(18)14-28-17-7-5-15(6-8-17)22-24-19-13-25(12-10-21(26)27)11-9-20(19)29-22/h1-8H,9-14H2,(H,26,27)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	10	n/a	n/a	n/a	n/a
Abbvie B.V.; AbbiVie Inc. US Patent					Assay Description The CHO-human-S1P5-Aeqorin assay was bought from Euroscreen, Brussels (Euroscreen, Technical dossier, Human Lysophospholid S1P5 (Edg8) receptor, DNA ...				US Patent US9670220 (2017) BindingDB Entry DOI: 10.7270/Q2QJ7FHD
					More data for this Ligand-Target Pair
Sphingosine 1-phosphate receptor 1 (Homo sapiens (Human))	BDBM195892 (US9670220, 47) Show SMILES OC(=O)CCN1CCc2oc(nc2C1)-c1ccc(OCc2ccccc2F)cc1 Show InChI InChI=1S/C22H21FN2O4/c23-18-4-2-1-3-16(18)14-28-17-7-5-15(6-8-17)22-24-19-13-25(12-10-21(26)27)11-9-20(19)29-22/h1-8H,9-14H2,(H,26,27)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	>3.20E+3	n/a	n/a	n/a	25
Abbvie B.V.; AbbiVie Inc. US Patent					Assay Description The CHO-K1-Human S1P1-c-AMP assay was performed at Euroscreenfast, Brussels (Euroscreen, Human S1P1 coupling Gi/0, (Edg1) receptor, catalog no: FAST-...				US Patent US9670220 (2017) BindingDB Entry DOI: 10.7270/Q2QJ7FHD
					More data for this Ligand-Target Pair
Sphingosine 1-phosphate receptor 3 (Homo sapiens (Human))	BDBM195892 (US9670220, 47) Show SMILES OC(=O)CCN1CCc2oc(nc2C1)-c1ccc(OCc2ccccc2F)cc1 Show InChI InChI=1S/C22H21FN2O4/c23-18-4-2-1-3-16(18)14-28-17-7-5-15(6-8-17)22-24-19-13-25(12-10-21(26)27)11-9-20(19)29-22/h1-8H,9-14H2,(H,26,27)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
Abbvie B.V.; AbbiVie Inc. US Patent					Assay Description The CHO-human-S1P3-Aeqorin assay (CHO/Gα16/AEQ/h-S1P3) was established at Solvay Pharmaceuticals. The plasmid DNA coding for the S1P3 receptor (...				US Patent US9670220 (2017) BindingDB Entry DOI: 10.7270/Q2QJ7FHD
					More data for this Ligand-Target Pair
Sphingosine 1-phosphate receptor 5 (Homo sapiens (Human))	BDBM195893 (US9670220, 53) Show SMILES OC(=O)CCCN1CCc2oc(nc2C1)-c1ccc(OCc2ccccc2)cc1 Show InChI InChI=1S/C23H24N2O4/c26-22(27)7-4-13-25-14-12-21-20(15-25)24-23(29-21)18-8-10-19(11-9-18)28-16-17-5-2-1-3-6-17/h1-3,5-6,8-11H,4,7,12-16H2,(H,26,27)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	13	n/a	n/a	n/a	n/a
Abbvie B.V.; AbbiVie Inc. US Patent					Assay Description The CHO-human-S1P5-Aeqorin assay was bought from Euroscreen, Brussels (Euroscreen, Technical dossier, Human Lysophospholid S1P5 (Edg8) receptor, DNA ...				US Patent US9670220 (2017) BindingDB Entry DOI: 10.7270/Q2QJ7FHD
					More data for this Ligand-Target Pair
Sphingosine 1-phosphate receptor 1 (Homo sapiens (Human))	BDBM195893 (US9670220, 53) Show SMILES OC(=O)CCCN1CCc2oc(nc2C1)-c1ccc(OCc2ccccc2)cc1 Show InChI InChI=1S/C23H24N2O4/c26-22(27)7-4-13-25-14-12-21-20(15-25)24-23(29-21)18-8-10-19(11-9-18)28-16-17-5-2-1-3-6-17/h1-3,5-6,8-11H,4,7,12-16H2,(H,26,27)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	>3.20E+4	n/a	n/a	n/a	n/a
Abbvie B.V.; AbbiVie Inc. US Patent					Assay Description The CHO-K1-human-S1P1-Acqorin assay was bought from Euroscreen Fast, Brussels (Euroscreen, Technical dossier, Human S1P1 (Edg1) receptor, DNA clone a...				US Patent US9670220 (2017) BindingDB Entry DOI: 10.7270/Q2QJ7FHD
					More data for this Ligand-Target Pair
Sphingosine 1-phosphate receptor 3 (Homo sapiens (Human))	BDBM195893 (US9670220, 53) Show SMILES OC(=O)CCCN1CCc2oc(nc2C1)-c1ccc(OCc2ccccc2)cc1 Show InChI InChI=1S/C23H24N2O4/c26-22(27)7-4-13-25-14-12-21-20(15-25)24-23(29-21)18-8-10-19(11-9-18)28-16-17-5-2-1-3-6-17/h1-3,5-6,8-11H,4,7,12-16H2,(H,26,27)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
Abbvie B.V.; AbbiVie Inc. US Patent					Assay Description The CHO-human-S1P3-Aeqorin assay (CHO/Gα16/AEQ/h-S1P3) was established at Solvay Pharmaceuticals. The plasmid DNA coding for the S1P3 receptor (...				US Patent US9670220 (2017) BindingDB Entry DOI: 10.7270/Q2QJ7FHD
					More data for this Ligand-Target Pair
Sphingosine 1-phosphate receptor 5 (Homo sapiens (Human))	BDBM195894 (US9670220, 57) Show SMILES OC(=O)CCCN1CCc2oc(nc2C1)-c1ccc(OCc2cccc(F)c2F)cc1 Show InChI InChI=1S/C23H22F2N2O4/c24-18-4-1-3-16(22(18)25)14-30-17-8-6-15(7-9-17)23-26-19-13-27(11-2-5-21(28)29)12-10-20(19)31-23/h1,3-4,6-9H,2,5,10-14H2,(H,28,29)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	10	n/a	n/a	n/a	n/a
Abbvie B.V.; AbbiVie Inc. US Patent					Assay Description The CHO-human-S1P5-Aeqorin assay was bought from Euroscreen, Brussels (Euroscreen, Technical dossier, Human Lysophospholid S1P5 (Edg8) receptor, DNA ...				US Patent US9670220 (2017) BindingDB Entry DOI: 10.7270/Q2QJ7FHD
					More data for this Ligand-Target Pair
Sphingosine 1-phosphate receptor 1 (Homo sapiens (Human))	BDBM195894 (US9670220, 57) Show SMILES OC(=O)CCCN1CCc2oc(nc2C1)-c1ccc(OCc2cccc(F)c2F)cc1 Show InChI InChI=1S/C23H22F2N2O4/c24-18-4-1-3-16(22(18)25)14-30-17-8-6-15(7-9-17)23-26-19-13-27(11-2-5-21(28)29)12-10-20(19)31-23/h1,3-4,6-9H,2,5,10-14H2,(H,28,29)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	>3.20E+3	n/a	n/a	n/a	25
Abbvie B.V.; AbbiVie Inc. US Patent					Assay Description The CHO-K1-Human S1P1-c-AMP assay was performed at Euroscreenfast, Brussels (Euroscreen, Human S1P1 coupling Gi/0, (Edg1) receptor, catalog no: FAST-...				US Patent US9670220 (2017) BindingDB Entry DOI: 10.7270/Q2QJ7FHD
					More data for this Ligand-Target Pair
Sphingosine 1-phosphate receptor 3 (Homo sapiens (Human))	BDBM195894 (US9670220, 57) Show SMILES OC(=O)CCCN1CCc2oc(nc2C1)-c1ccc(OCc2cccc(F)c2F)cc1 Show InChI InChI=1S/C23H22F2N2O4/c24-18-4-1-3-16(22(18)25)14-30-17-8-6-15(7-9-17)23-26-19-13-27(11-2-5-21(28)29)12-10-20(19)31-23/h1,3-4,6-9H,2,5,10-14H2,(H,28,29)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
Abbvie B.V.; AbbiVie Inc. US Patent					Assay Description The CHO-human-S1P3-Aeqorin assay (CHO/Gα16/AEQ/h-S1P3) was established at Solvay Pharmaceuticals. The plasmid DNA coding for the S1P3 receptor (...				US Patent US9670220 (2017) BindingDB Entry DOI: 10.7270/Q2QJ7FHD
					More data for this Ligand-Target Pair
Sphingosine 1-phosphate receptor 5 (Homo sapiens (Human))	BDBM195895 (US9670220, 73) Show SMILES OC(=O)CCCN1CCc2oc(cc2C1)-c1ccc(OCc2ccccc2F)c(F)c1 Show InChI InChI=1S/C24H23F2NO4/c25-19-5-2-1-4-17(19)15-30-22-8-7-16(12-20(22)26)23-13-18-14-27(10-3-6-24(28)29)11-9-21(18)31-23/h1-2,4-5,7-8,12-13H,3,6,9-11,14-15H2,(H,28,29)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	6.30	n/a	n/a	n/a	n/a
Abbvie B.V.; AbbiVie Inc. US Patent					Assay Description The CHO-human-S1P5-Aeqorin assay was bought from Euroscreen, Brussels (Euroscreen, Technical dossier, Human Lysophospholid S1P5 (Edg8) receptor, DNA ...				US Patent US9670220 (2017) BindingDB Entry DOI: 10.7270/Q2QJ7FHD
					More data for this Ligand-Target Pair
Sphingosine 1-phosphate receptor 1 (Homo sapiens (Human))	BDBM195895 (US9670220, 73) Show SMILES OC(=O)CCCN1CCc2oc(cc2C1)-c1ccc(OCc2ccccc2F)c(F)c1 Show InChI InChI=1S/C24H23F2NO4/c25-19-5-2-1-4-17(19)15-30-22-8-7-16(12-20(22)26)23-13-18-14-27(10-3-6-24(28)29)11-9-21(18)31-23/h1-2,4-5,7-8,12-13H,3,6,9-11,14-15H2,(H,28,29)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	10	n/a	n/a	n/a	25
Abbvie B.V.; AbbiVie Inc. US Patent					Assay Description The CHO-K1-Human S1P1-c-AMP assay was performed at Euroscreenfast, Brussels (Euroscreen, Human S1P1 coupling Gi/0, (Edg1) receptor, catalog no: FAST-...				US Patent US9670220 (2017) BindingDB Entry DOI: 10.7270/Q2QJ7FHD
					More data for this Ligand-Target Pair
Sphingosine 1-phosphate receptor 3 (Homo sapiens (Human))	BDBM195895 (US9670220, 73) Show SMILES OC(=O)CCCN1CCc2oc(cc2C1)-c1ccc(OCc2ccccc2F)c(F)c1 Show InChI InChI=1S/C24H23F2NO4/c25-19-5-2-1-4-17(19)15-30-22-8-7-16(12-20(22)26)23-13-18-14-27(10-3-6-24(28)29)11-9-21(18)31-23/h1-2,4-5,7-8,12-13H,3,6,9-11,14-15H2,(H,28,29)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	500	n/a	n/a	n/a	n/a
Abbvie B.V.; AbbiVie Inc. US Patent					Assay Description The CHO-human-S1P3-Aeqorin assay (CHO/Gα16/AEQ/h-S1P3) was established at Solvay Pharmaceuticals. The plasmid DNA coding for the S1P3 receptor (...				US Patent US9670220 (2017) BindingDB Entry DOI: 10.7270/Q2QJ7FHD
					More data for this Ligand-Target Pair
Sphingosine 1-phosphate receptor 5 (Homo sapiens (Human))	BDBM195896 (US9670220, 76) Show SMILES CC(CC(O)=O)N1CCc2oc(cc2C1)-c1ccc(OCc2ccccc2)cc1 Show InChI InChI=1S/C24H25NO4/c1-17(13-24(26)27)25-12-11-22-20(15-25)14-23(29-22)19-7-9-21(10-8-19)28-16-18-5-3-2-4-6-18/h2-10,14,17H,11-13,15-16H2,1H3,(H,26,27)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	7.90	n/a	n/a	n/a	n/a
Abbvie B.V.; AbbiVie Inc. US Patent					Assay Description The CHO-human-S1P5-Aeqorin assay was bought from Euroscreen, Brussels (Euroscreen, Technical dossier, Human Lysophospholid S1P5 (Edg8) receptor, DNA ...				US Patent US9670220 (2017) BindingDB Entry DOI: 10.7270/Q2QJ7FHD
					More data for this Ligand-Target Pair
Sphingosine 1-phosphate receptor 1 (Homo sapiens (Human))	BDBM195896 (US9670220, 76) Show SMILES CC(CC(O)=O)N1CCc2oc(cc2C1)-c1ccc(OCc2ccccc2)cc1 Show InChI InChI=1S/C24H25NO4/c1-17(13-24(26)27)25-12-11-22-20(15-25)14-23(29-22)19-7-9-21(10-8-19)28-16-18-5-3-2-4-6-18/h2-10,14,17H,11-13,15-16H2,1H3,(H,26,27)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	250	n/a	n/a	n/a	25
Abbvie B.V.; AbbiVie Inc. US Patent					Assay Description The CHO-K1-Human S1P1-c-AMP assay was performed at Euroscreenfast, Brussels (Euroscreen, Human S1P1 coupling Gi/0, (Edg1) receptor, catalog no: FAST-...				US Patent US9670220 (2017) BindingDB Entry DOI: 10.7270/Q2QJ7FHD
					More data for this Ligand-Target Pair
Sphingosine 1-phosphate receptor 3 (Homo sapiens (Human))	BDBM195896 (US9670220, 76) Show SMILES CC(CC(O)=O)N1CCc2oc(cc2C1)-c1ccc(OCc2ccccc2)cc1 Show InChI InChI=1S/C24H25NO4/c1-17(13-24(26)27)25-12-11-22-20(15-25)14-23(29-22)19-7-9-21(10-8-19)28-16-18-5-3-2-4-6-18/h2-10,14,17H,11-13,15-16H2,1H3,(H,26,27)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
Abbvie B.V.; AbbiVie Inc. US Patent					Assay Description The CHO-human-S1P3-Aeqorin assay (CHO/Gα16/AEQ/h-S1P3) was established at Solvay Pharmaceuticals. The plasmid DNA coding for the S1P3 receptor (...				US Patent US9670220 (2017) BindingDB Entry DOI: 10.7270/Q2QJ7FHD
					More data for this Ligand-Target Pair
Sphingosine 1-phosphate receptor 5 (Homo sapiens (Human))	BDBM195897 (US9670220, 77) Show SMILES CC(CN1CCc2oc(cc2C1)-c1ccc(OCc2ccc(Cl)cc2)cc1)C(O)=O Show InChI InChI=1S/C24H24ClNO4/c1-16(24(27)28)13-26-11-10-22-19(14-26)12-23(30-22)18-4-8-21(9-5-18)29-15-17-2-6-20(25)7-3-17/h2-9,12,16H,10-11,13-15H2,1H3,(H,27,28)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	4	n/a	n/a	n/a	n/a
Abbvie B.V.; AbbiVie Inc. US Patent					Assay Description The CHO-human-S1P5-Aeqorin assay was bought from Euroscreen, Brussels (Euroscreen, Technical dossier, Human Lysophospholid S1P5 (Edg8) receptor, DNA ...				US Patent US9670220 (2017) BindingDB Entry DOI: 10.7270/Q2QJ7FHD
					More data for this Ligand-Target Pair
Sphingosine 1-phosphate receptor 1 (Homo sapiens (Human))	BDBM195897 (US9670220, 77) Show SMILES CC(CN1CCc2oc(cc2C1)-c1ccc(OCc2ccc(Cl)cc2)cc1)C(O)=O Show InChI InChI=1S/C24H24ClNO4/c1-16(24(27)28)13-26-11-10-22-19(14-26)12-23(30-22)18-4-8-21(9-5-18)29-15-17-2-6-20(25)7-3-17/h2-9,12,16H,10-11,13-15H2,1H3,(H,27,28)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	32	n/a	n/a	n/a	25
Abbvie B.V.; AbbiVie Inc. US Patent					Assay Description The CHO-K1-Human S1P1-c-AMP assay was performed at Euroscreenfast, Brussels (Euroscreen, Human S1P1 coupling Gi/0, (Edg1) receptor, catalog no: FAST-...				US Patent US9670220 (2017) BindingDB Entry DOI: 10.7270/Q2QJ7FHD
					More data for this Ligand-Target Pair
Sphingosine 1-phosphate receptor 3 (Homo sapiens (Human))	BDBM195897 (US9670220, 77) Show SMILES CC(CN1CCc2oc(cc2C1)-c1ccc(OCc2ccc(Cl)cc2)cc1)C(O)=O Show InChI InChI=1S/C24H24ClNO4/c1-16(24(27)28)13-26-11-10-22-19(14-26)12-23(30-22)18-4-8-21(9-5-18)29-15-17-2-6-20(25)7-3-17/h2-9,12,16H,10-11,13-15H2,1H3,(H,27,28)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	790	n/a	n/a	n/a	n/a
Abbvie B.V.; AbbiVie Inc. US Patent					Assay Description The CHO-human-S1P3-Aeqorin assay (CHO/Gα16/AEQ/h-S1P3) was established at Solvay Pharmaceuticals. The plasmid DNA coding for the S1P3 receptor (...				US Patent US9670220 (2017) BindingDB Entry DOI: 10.7270/Q2QJ7FHD
					More data for this Ligand-Target Pair
Sphingosine 1-phosphate receptor 5 (Homo sapiens (Human))	BDBM195899 (US9670220, 85) Show SMILES OC(=O)CCCN1CCc2oc(nc2C1)-c1ccc(OCc2ccc(cc2)C(F)(F)F)c(F)c1 Show InChI InChI=1S/C24H22F4N2O4/c25-18-12-16(5-8-20(18)33-14-15-3-6-17(7-4-15)24(26,27)28)23-29-19-13-30(10-1-2-22(31)32)11-9-21(19)34-23/h3-8,12H,1-2,9-11,13-14H2,(H,31,32)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	2.5	n/a	n/a	n/a	n/a
Abbvie B.V.; AbbiVie Inc. US Patent					Assay Description The CHO-human-S1P5-Aeqorin assay was bought from Euroscreen, Brussels (Euroscreen, Technical dossier, Human Lysophospholid S1P5 (Edg8) receptor, DNA ...				US Patent US9670220 (2017) BindingDB Entry DOI: 10.7270/Q2QJ7FHD
					More data for this Ligand-Target Pair
Sphingosine 1-phosphate receptor 1 (Homo sapiens (Human))	BDBM195899 (US9670220, 85) Show SMILES OC(=O)CCCN1CCc2oc(nc2C1)-c1ccc(OCc2ccc(cc2)C(F)(F)F)c(F)c1 Show InChI InChI=1S/C24H22F4N2O4/c25-18-12-16(5-8-20(18)33-14-15-3-6-17(7-4-15)24(26,27)28)23-29-19-13-30(10-1-2-22(31)32)11-9-21(19)34-23/h3-8,12H,1-2,9-11,13-14H2,(H,31,32)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	>3.20E+3	n/a	n/a	n/a	25
Abbvie B.V.; AbbiVie Inc. US Patent					Assay Description The CHO-K1-Human S1P1-c-AMP assay was performed at Euroscreenfast, Brussels (Euroscreen, Human S1P1 coupling Gi/0, (Edg1) receptor, catalog no: FAST-...				US Patent US9670220 (2017) BindingDB Entry DOI: 10.7270/Q2QJ7FHD
					More data for this Ligand-Target Pair
Sphingosine 1-phosphate receptor 3 (Homo sapiens (Human))	BDBM195899 (US9670220, 85) Show SMILES OC(=O)CCCN1CCc2oc(nc2C1)-c1ccc(OCc2ccc(cc2)C(F)(F)F)c(F)c1 Show InChI InChI=1S/C24H22F4N2O4/c25-18-12-16(5-8-20(18)33-14-15-3-6-17(7-4-15)24(26,27)28)23-29-19-13-30(10-1-2-22(31)32)11-9-21(19)34-23/h3-8,12H,1-2,9-11,13-14H2,(H,31,32)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	500	n/a	n/a	n/a	n/a
Abbvie B.V.; AbbiVie Inc. US Patent					Assay Description The CHO-human-S1P3-Aeqorin assay (CHO/Gα16/AEQ/h-S1P3) was established at Solvay Pharmaceuticals. The plasmid DNA coding for the S1P3 receptor (...				US Patent US9670220 (2017) BindingDB Entry DOI: 10.7270/Q2QJ7FHD
					More data for this Ligand-Target Pair
Sphingosine 1-phosphate receptor 5 (Homo sapiens (Human))	BDBM196174 (US9670220, 89) Show SMILES Cc1cc(ccc1OCc1ccccc1F)-c1nc2CN(CCCC(O)=O)CCc2o1 Show InChI InChI=1S/C24H25FN2O4/c1-16-13-17(8-9-21(16)30-15-18-5-2-3-6-19(18)25)24-26-20-14-27(11-4-7-23(28)29)12-10-22(20)31-24/h2-3,5-6,8-9,13H,4,7,10-12,14-15H2,1H3,(H,28,29)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	6.30	n/a	n/a	n/a	n/a
Abbvie B.V.; AbbiVie Inc. US Patent					Assay Description The CHO-human-S1P5-Aeqorin assay was bought from Euroscreen, Brussels (Euroscreen, Technical dossier, Human Lysophospholid S1P5 (Edg8) receptor, DNA ...				US Patent US9670220 (2017) BindingDB Entry DOI: 10.7270/Q2QJ7FHD
					More data for this Ligand-Target Pair
Sphingosine 1-phosphate receptor 1 (Homo sapiens (Human))	BDBM196174 (US9670220, 89) Show SMILES Cc1cc(ccc1OCc1ccccc1F)-c1nc2CN(CCCC(O)=O)CCc2o1 Show InChI InChI=1S/C24H25FN2O4/c1-16-13-17(8-9-21(16)30-15-18-5-2-3-6-19(18)25)24-26-20-14-27(11-4-7-23(28)29)12-10-22(20)31-24/h2-3,5-6,8-9,13H,4,7,10-12,14-15H2,1H3,(H,28,29)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	1.30E+3	n/a	n/a	n/a	25
Abbvie B.V.; AbbiVie Inc. US Patent					Assay Description The CHO-K1-Human S1P1-c-AMP assay was performed at Euroscreenfast, Brussels (Euroscreen, Human S1P1 coupling Gi/0, (Edg1) receptor, catalog no: FAST-...				US Patent US9670220 (2017) BindingDB Entry DOI: 10.7270/Q2QJ7FHD
					More data for this Ligand-Target Pair
Sphingosine 1-phosphate receptor 3 (Homo sapiens (Human))	BDBM196174 (US9670220, 89) Show SMILES Cc1cc(ccc1OCc1ccccc1F)-c1nc2CN(CCCC(O)=O)CCc2o1 Show InChI InChI=1S/C24H25FN2O4/c1-16-13-17(8-9-21(16)30-15-18-5-2-3-6-19(18)25)24-26-20-14-27(11-4-7-23(28)29)12-10-22(20)31-24/h2-3,5-6,8-9,13H,4,7,10-12,14-15H2,1H3,(H,28,29)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
Abbvie B.V.; AbbiVie Inc. US Patent					Assay Description The CHO-human-S1P3-Aeqorin assay (CHO/Gα16/AEQ/h-S1P3) was established at Solvay Pharmaceuticals. The plasmid DNA coding for the S1P3 receptor (...				US Patent US9670220 (2017) BindingDB Entry DOI: 10.7270/Q2QJ7FHD
					More data for this Ligand-Target Pair
Sphingosine 1-phosphate receptor 5 (Homo sapiens (Human))	BDBM196179 (US9670220, 146) Show SMILES CC(CN1CCc2oc(nc2C1)-c1ccc(OCc2ccccc2)cc1)C(O)=O Show InChI InChI=1S/C23H24N2O4/c1-16(23(26)27)13-25-12-11-21-20(14-25)24-22(29-21)18-7-9-19(10-8-18)28-15-17-5-3-2-4-6-17/h2-10,16H,11-15H2,1H3,(H,26,27)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	16	n/a	n/a	n/a	n/a
Abbvie B.V.; AbbiVie Inc. US Patent					Assay Description The CHO-human-S1P5-Aeqorin assay was bought from Euroscreen, Brussels (Euroscreen, Technical dossier, Human Lysophospholid S1P5 (Edg8) receptor, DNA ...				US Patent US9670220 (2017) BindingDB Entry DOI: 10.7270/Q2QJ7FHD
					More data for this Ligand-Target Pair
Sphingosine 1-phosphate receptor 1 (Homo sapiens (Human))	BDBM196179 (US9670220, 146) Show SMILES CC(CN1CCc2oc(nc2C1)-c1ccc(OCc2ccccc2)cc1)C(O)=O Show InChI InChI=1S/C23H24N2O4/c1-16(23(26)27)13-25-12-11-21-20(14-25)24-22(29-21)18-7-9-19(10-8-18)28-15-17-5-3-2-4-6-17/h2-10,16H,11-15H2,1H3,(H,26,27)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	>3.20E+3	n/a	n/a	n/a	25
Abbvie B.V.; AbbiVie Inc. US Patent					Assay Description The CHO-K1-Human S1P1-c-AMP assay was performed at Euroscreenfast, Brussels (Euroscreen, Human S1P1 coupling Gi/0, (Edg1) receptor, catalog no: FAST-...				US Patent US9670220 (2017) BindingDB Entry DOI: 10.7270/Q2QJ7FHD
					More data for this Ligand-Target Pair
Sphingosine 1-phosphate receptor 3 (Homo sapiens (Human))	BDBM196179 (US9670220, 146) Show SMILES CC(CN1CCc2oc(nc2C1)-c1ccc(OCc2ccccc2)cc1)C(O)=O Show InChI InChI=1S/C23H24N2O4/c1-16(23(26)27)13-25-12-11-21-20(14-25)24-22(29-21)18-7-9-19(10-8-18)28-15-17-5-3-2-4-6-17/h2-10,16H,11-15H2,1H3,(H,26,27)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
Abbvie B.V.; AbbiVie Inc. US Patent					Assay Description The CHO-human-S1P3-Aeqorin assay (CHO/Gα16/AEQ/h-S1P3) was established at Solvay Pharmaceuticals. The plasmid DNA coding for the S1P3 receptor (...				US Patent US9670220 (2017) BindingDB Entry DOI: 10.7270/Q2QJ7FHD
					More data for this Ligand-Target Pair
Sphingosine 1-phosphate receptor 5 (Homo sapiens (Human))	BDBM196180 (US9670220, 156) Show SMILES CC(CN1CCc2oc(nc2C1)-c1ccc(OCc2ccc(cc2)C(F)(F)F)cc1)C(O)=O Show InChI InChI=1S/C24H23F3N2O4/c1-15(23(30)31)12-29-11-10-21-20(13-29)28-22(33-21)17-4-8-19(9-5-17)32-14-16-2-6-18(7-3-16)24(25,26)27/h2-9,15H,10-14H2,1H3,(H,30,31)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	4	n/a	n/a	n/a	n/a
Abbvie B.V.; AbbiVie Inc. US Patent					Assay Description The CHO-human-S1P5-Aeqorin assay was bought from Euroscreen, Brussels (Euroscreen, Technical dossier, Human Lysophospholid S1P5 (Edg8) receptor, DNA ...				US Patent US9670220 (2017) BindingDB Entry DOI: 10.7270/Q2QJ7FHD
					More data for this Ligand-Target Pair
Sphingosine 1-phosphate receptor 1 (Homo sapiens (Human))	BDBM196180 (US9670220, 156) Show SMILES CC(CN1CCc2oc(nc2C1)-c1ccc(OCc2ccc(cc2)C(F)(F)F)cc1)C(O)=O Show InChI InChI=1S/C24H23F3N2O4/c1-15(23(30)31)12-29-11-10-21-20(13-29)28-22(33-21)17-4-8-19(9-5-17)32-14-16-2-6-18(7-3-16)24(25,26)27/h2-9,15H,10-14H2,1H3,(H,30,31)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	630	n/a	n/a	n/a	25
Abbvie B.V.; AbbiVie Inc. US Patent					Assay Description The CHO-K1-Human S1P1-c-AMP assay was performed at Euroscreenfast, Brussels (Euroscreen, Human S1P1 coupling Gi/0, (Edg1) receptor, catalog no: FAST-...				US Patent US9670220 (2017) BindingDB Entry DOI: 10.7270/Q2QJ7FHD
					More data for this Ligand-Target Pair
Sphingosine 1-phosphate receptor 3 (Homo sapiens (Human))	BDBM196180 (US9670220, 156) Show SMILES CC(CN1CCc2oc(nc2C1)-c1ccc(OCc2ccc(cc2)C(F)(F)F)cc1)C(O)=O Show InChI InChI=1S/C24H23F3N2O4/c1-15(23(30)31)12-29-11-10-21-20(13-29)28-22(33-21)17-4-8-19(9-5-17)32-14-16-2-6-18(7-3-16)24(25,26)27/h2-9,15H,10-14H2,1H3,(H,30,31)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	3.20E+3	n/a	n/a	n/a	n/a
Abbvie B.V.; AbbiVie Inc. US Patent					Assay Description The CHO-human-S1P3-Aeqorin assay (CHO/Gα16/AEQ/h-S1P3) was established at Solvay Pharmaceuticals. The plasmid DNA coding for the S1P3 receptor (...				US Patent US9670220 (2017) BindingDB Entry DOI: 10.7270/Q2QJ7FHD
					More data for this Ligand-Target Pair
Sphingosine 1-phosphate receptor 5 (Homo sapiens (Human))	BDBM196198 (US9670220, 157) Show SMILES CC(CN1CCc2oc(nc2C1)-c1ccc(OCc2ccc(Cl)cc2)cc1)C(O)=O Show InChI InChI=1S/C23H23ClN2O4/c1-15(23(27)28)12-26-11-10-21-20(13-26)25-22(30-21)17-4-8-19(9-5-17)29-14-16-2-6-18(24)7-3-16/h2-9,15H,10-14H2,1H3,(H,27,28)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	7.90	n/a	n/a	n/a	n/a
Abbvie B.V.; AbbiVie Inc. US Patent					Assay Description The CHO-human-S1P5-Aeqorin assay was bought from Euroscreen, Brussels (Euroscreen, Technical dossier, Human Lysophospholid S1P5 (Edg8) receptor, DNA ...				US Patent US9670220 (2017) BindingDB Entry DOI: 10.7270/Q2QJ7FHD
					More data for this Ligand-Target Pair
Sphingosine 1-phosphate receptor 1 (Homo sapiens (Human))	BDBM196198 (US9670220, 157) Show SMILES CC(CN1CCc2oc(nc2C1)-c1ccc(OCc2ccc(Cl)cc2)cc1)C(O)=O Show InChI InChI=1S/C23H23ClN2O4/c1-15(23(27)28)12-26-11-10-21-20(13-26)25-22(30-21)17-4-8-19(9-5-17)29-14-16-2-6-18(24)7-3-16/h2-9,15H,10-14H2,1H3,(H,27,28)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	630	n/a	n/a	n/a	25
Abbvie B.V.; AbbiVie Inc. US Patent					Assay Description The CHO-K1-Human S1P1-c-AMP assay was performed at Euroscreenfast, Brussels (Euroscreen, Human S1P1 coupling Gi/0, (Edg1) receptor, catalog no: FAST-...				US Patent US9670220 (2017) BindingDB Entry DOI: 10.7270/Q2QJ7FHD
					More data for this Ligand-Target Pair
Sphingosine 1-phosphate receptor 3 (Homo sapiens (Human))	BDBM196198 (US9670220, 157) Show SMILES CC(CN1CCc2oc(nc2C1)-c1ccc(OCc2ccc(Cl)cc2)cc1)C(O)=O Show InChI InChI=1S/C23H23ClN2O4/c1-15(23(27)28)12-26-11-10-21-20(13-26)25-22(30-21)17-4-8-19(9-5-17)29-14-16-2-6-18(24)7-3-16/h2-9,15H,10-14H2,1H3,(H,27,28)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	5.00E+3	n/a	n/a	n/a	n/a
Abbvie B.V.; AbbiVie Inc. US Patent					Assay Description The CHO-human-S1P3-Aeqorin assay (CHO/Gα16/AEQ/h-S1P3) was established at Solvay Pharmaceuticals. The plasmid DNA coding for the S1P3 receptor (...				US Patent US9670220 (2017) BindingDB Entry DOI: 10.7270/Q2QJ7FHD
					More data for this Ligand-Target Pair
Sphingosine 1-phosphate receptor 5 (Homo sapiens (Human))	BDBM196211 (US9670220, 175) Show SMILES CC(CC(O)=O)N1CCc2oc(nc2C1)-c1ccc(OCc2cccc(F)c2F)cc1 Show InChI InChI=1S/C23H22F2N2O4/c1-14(11-21(28)29)27-10-9-20-19(12-27)26-23(31-20)15-5-7-17(8-6-15)30-13-16-3-2-4-18(24)22(16)25/h2-8,14H,9-13H2,1H3,(H,28,29)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	5	n/a	n/a	n/a	n/a
Abbvie B.V.; AbbiVie Inc. US Patent					Assay Description The CHO-human-S1P5-Aeqorin assay was bought from Euroscreen, Brussels (Euroscreen, Technical dossier, Human Lysophospholid S1P5 (Edg8) receptor, DNA ...				US Patent US9670220 (2017) BindingDB Entry DOI: 10.7270/Q2QJ7FHD
					More data for this Ligand-Target Pair
Sphingosine 1-phosphate receptor 1 (Homo sapiens (Human))	BDBM196211 (US9670220, 175) Show SMILES CC(CC(O)=O)N1CCc2oc(nc2C1)-c1ccc(OCc2cccc(F)c2F)cc1 Show InChI InChI=1S/C23H22F2N2O4/c1-14(11-21(28)29)27-10-9-20-19(12-27)26-23(31-20)15-5-7-17(8-6-15)30-13-16-3-2-4-18(24)22(16)25/h2-8,14H,9-13H2,1H3,(H,28,29)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	>3.20E+3	n/a	n/a	n/a	25
Abbvie B.V.; AbbiVie Inc. US Patent					Assay Description The CHO-K1-Human S1P1-c-AMP assay was performed at Euroscreenfast, Brussels (Euroscreen, Human S1P1 coupling Gi/0, (Edg1) receptor, catalog no: FAST-...				US Patent US9670220 (2017) BindingDB Entry DOI: 10.7270/Q2QJ7FHD
					More data for this Ligand-Target Pair
Sphingosine 1-phosphate receptor 3 (Homo sapiens (Human))	BDBM196211 (US9670220, 175) Show SMILES CC(CC(O)=O)N1CCc2oc(nc2C1)-c1ccc(OCc2cccc(F)c2F)cc1 Show InChI InChI=1S/C23H22F2N2O4/c1-14(11-21(28)29)27-10-9-20-19(12-27)26-23(31-20)15-5-7-17(8-6-15)30-13-16-3-2-4-18(24)22(16)25/h2-8,14H,9-13H2,1H3,(H,28,29)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	1.60E+3	n/a	n/a	n/a	n/a
Abbvie B.V.; AbbiVie Inc. US Patent					Assay Description The CHO-human-S1P3-Aeqorin assay (CHO/Gα16/AEQ/h-S1P3) was established at Solvay Pharmaceuticals. The plasmid DNA coding for the S1P3 receptor (...				US Patent US9670220 (2017) BindingDB Entry DOI: 10.7270/Q2QJ7FHD
					More data for this Ligand-Target Pair
Sphingosine 1-phosphate receptor 5 (Homo sapiens (Human))	BDBM196221 (US9670220, 211) Show SMILES OC(=O)CCCN1CCc2oc(nc2C1)-c1ccc(OCc2ccc(Cl)cc2)cc1F Show InChI InChI=1S/C23H22ClFN2O4/c24-16-5-3-15(4-6-16)14-30-17-7-8-18(19(25)12-17)23-26-20-13-27(10-1-2-22(28)29)11-9-21(20)31-23/h3-8,12H,1-2,9-11,13-14H2,(H,28,29)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	5	n/a	n/a	n/a	n/a
Abbvie B.V.; AbbiVie Inc. US Patent					Assay Description The CHO-human-S1P5-Aeqorin assay was bought from Euroscreen, Brussels (Euroscreen, Technical dossier, Human Lysophospholid S1P5 (Edg8) receptor, DNA ...				US Patent US9670220 (2017) BindingDB Entry DOI: 10.7270/Q2QJ7FHD
					More data for this Ligand-Target Pair
Sphingosine 1-phosphate receptor 1 (Homo sapiens (Human))	BDBM196221 (US9670220, 211) Show SMILES OC(=O)CCCN1CCc2oc(nc2C1)-c1ccc(OCc2ccc(Cl)cc2)cc1F Show InChI InChI=1S/C23H22ClFN2O4/c24-16-5-3-15(4-6-16)14-30-17-7-8-18(19(25)12-17)23-26-20-13-27(10-1-2-22(28)29)11-9-21(20)31-23/h3-8,12H,1-2,9-11,13-14H2,(H,28,29)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	790	n/a	n/a	n/a	25
Abbvie B.V.; AbbiVie Inc. US Patent					Assay Description The CHO-K1-Human S1P1-c-AMP assay was performed at Euroscreenfast, Brussels (Euroscreen, Human S1P1 coupling Gi/0, (Edg1) receptor, catalog no: FAST-...				US Patent US9670220 (2017) BindingDB Entry DOI: 10.7270/Q2QJ7FHD
					More data for this Ligand-Target Pair
Sphingosine 1-phosphate receptor 3 (Homo sapiens (Human))	BDBM196221 (US9670220, 211) Show SMILES OC(=O)CCCN1CCc2oc(nc2C1)-c1ccc(OCc2ccc(Cl)cc2)cc1F Show InChI InChI=1S/C23H22ClFN2O4/c24-16-5-3-15(4-6-16)14-30-17-7-8-18(19(25)12-17)23-26-20-13-27(10-1-2-22(28)29)11-9-21(20)31-23/h3-8,12H,1-2,9-11,13-14H2,(H,28,29)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
Abbvie B.V.; AbbiVie Inc. US Patent					Assay Description The CHO-human-S1P3-Aeqorin assay (CHO/Gα16/AEQ/h-S1P3) was established at Solvay Pharmaceuticals. The plasmid DNA coding for the S1P3 receptor (...				US Patent US9670220 (2017) BindingDB Entry DOI: 10.7270/Q2QJ7FHD
					More data for this Ligand-Target Pair
Sphingosine 1-phosphate receptor 5 (Homo sapiens (Human))	BDBM196260 (US9670220, 227) Show SMILES OC(=O)CCCN1CCc2oc(nc2C1)-c1ccc(OCc2ccc(Cl)c(Cl)c2)c(F)c1 Show InChI InChI=1S/C23H21Cl2FN2O4/c24-16-5-3-14(10-17(16)25)13-31-20-6-4-15(11-18(20)26)23-27-19-12-28(8-1-2-22(29)30)9-7-21(19)32-23/h3-6,10-11H,1-2,7-9,12-13H2,(H,29,30)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	3.20	n/a	n/a	n/a	n/a
Abbvie B.V.; AbbiVie Inc. US Patent					Assay Description The CHO-human-S1P5-Aeqorin assay was bought from Euroscreen, Brussels (Euroscreen, Technical dossier, Human Lysophospholid S1P5 (Edg8) receptor, DNA ...				US Patent US9670220 (2017) BindingDB Entry DOI: 10.7270/Q2QJ7FHD
					More data for this Ligand-Target Pair
Sphingosine 1-phosphate receptor 1 (Homo sapiens (Human))	BDBM196260 (US9670220, 227) Show SMILES OC(=O)CCCN1CCc2oc(nc2C1)-c1ccc(OCc2ccc(Cl)c(Cl)c2)c(F)c1 Show InChI InChI=1S/C23H21Cl2FN2O4/c24-16-5-3-14(10-17(16)25)13-31-20-6-4-15(11-18(20)26)23-27-19-12-28(8-1-2-22(29)30)9-7-21(19)32-23/h3-6,10-11H,1-2,7-9,12-13H2,(H,29,30)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	1.00E+3	n/a	n/a	n/a	25
Abbvie B.V.; AbbiVie Inc. US Patent					Assay Description The CHO-K1-Human S1P1-c-AMP assay was performed at Euroscreenfast, Brussels (Euroscreen, Human S1P1 coupling Gi/0, (Edg1) receptor, catalog no: FAST-...				US Patent US9670220 (2017) BindingDB Entry DOI: 10.7270/Q2QJ7FHD
					More data for this Ligand-Target Pair

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