Found 679 hits with Last Name = 'currie' and Initial = 'm' Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Nitric oxide synthase, inducible
(Mus musculus (mouse)) | BDBM50055281
(2-Ethyl-isothiourea | CHEMBL321691 | ETHYLISOTHIOU...)Show InChI InChI=1S/C3H8N2S/c1-2-6-3(4)5/h2H2,1H3,(H3,4,5) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| Purchase
CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem
Patents
Similars
| PDB Article PubMed
| 5.20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Washington University Medical School
Curated by ChEMBL
| Assay Description Binding affinity against mouse Inducible nitric oxide synthase (iNOS) |
J Med Chem 39: 5110-8 (1997)
Article DOI: 10.1021/jm960481q BindingDB Entry DOI: 10.7270/Q29W0DKZ |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
Nitric oxide synthase, inducible
(Homo sapiens (Human)) | BDBM50064015
(7-Propyl-azepan-(2Z)-ylideneamine; hydrochloride |...)Show InChI InChI=1S/C9H18N2/c1-2-5-8-6-3-4-7-9(10)11-8/h8H,2-7H2,1H3,(H2,10,11) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 90 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description Inhibitory activity against L-arginine binding to Inducible nitric oxide synthase |
J Med Chem 41: 1361-6 (1998)
Article DOI: 10.1021/jm9704715 BindingDB Entry DOI: 10.7270/Q2348M29 |
More data for this Ligand-Target Pair | |
Sodium-dependent serotonin transporter
(Homo sapiens (Human)) | BDBM50371827
(CHEMBL256227)Show InChI InChI=1S/C19H31NO2/c1-5-13-22-19(16-10-8-11-18(14-16)21-4)12-7-6-9-17(19)15-20(2)3/h8,10-11,14,17H,5-7,9,12-13,15H2,1-4H3/t17-,19+/m1/s1 | PDB
KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 25 | n/a | n/a | n/a | n/a | n/a | n/a |
Sepracor Inc.
Curated by ChEMBL
| Assay Description Inhibition of SERT mediated 5-hydroxytryptamine uptake |
Bioorg Med Chem Lett 18: 1674-80 (2008)
Article DOI: 10.1016/j.bmcl.2008.01.051 BindingDB Entry DOI: 10.7270/Q2VQ33HQ |
More data for this Ligand-Target Pair | |
Sodium-dependent serotonin transporter
(Homo sapiens (Human)) | BDBM50371825
(CHEMBL404197)Show SMILES COc1cccc(c1)[C@]1(CCCC[C@@H]1CN(C)C)OCC1CC1 Show InChI InChI=1S/C20H31NO2/c1-21(2)14-18-7-4-5-12-20(18,23-15-16-10-11-16)17-8-6-9-19(13-17)22-3/h6,8-9,13,16,18H,4-5,7,10-12,14-15H2,1-3H3/t18-,20+/m1/s1 | PDB
KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 25 | n/a | n/a | n/a | n/a | n/a | n/a |
Sepracor Inc.
Curated by ChEMBL
| Assay Description Inhibition of SERT mediated 5-hydroxytryptamine uptake |
Bioorg Med Chem Lett 18: 1674-80 (2008)
Article DOI: 10.1016/j.bmcl.2008.01.051 BindingDB Entry DOI: 10.7270/Q2VQ33HQ |
More data for this Ligand-Target Pair | |
Mu-type opioid receptor
(Homo sapiens (Human)) | BDBM50176263
(3-((1R,2R)-2-((dimethylamino)methyl)-1-hydroxycycl...)Show InChI InChI=1S/C15H23NO2/c1-16(2)11-13-6-3-4-9-15(13,18)12-7-5-8-14(17)10-12/h5,7-8,10,13,17-18H,3-4,6,9,11H2,1-2H3/t13-,15+/m1/s1 | PDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 47 | n/a | n/a | n/a | n/a | n/a | n/a |
Sepracor Inc.
Curated by ChEMBL
| Assay Description Binding affinity to mu opioid receptor |
Bioorg Med Chem Lett 18: 1674-80 (2008)
Article DOI: 10.1016/j.bmcl.2008.01.051 BindingDB Entry DOI: 10.7270/Q2VQ33HQ |
More data for this Ligand-Target Pair | |
Mu-type opioid receptor
(Homo sapiens (Human)) | BDBM50371815
(CHEMBL402116)Show InChI InChI=1S/C15H23NO2/c1-16-11-13-6-3-4-9-15(13,18-2)12-7-5-8-14(17)10-12/h5,7-8,10,13,16-17H,3-4,6,9,11H2,1-2H3/t13-,15+/m1/s1 | PDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 48 | n/a | n/a | n/a | n/a | n/a | n/a |
Sepracor Inc.
Curated by ChEMBL
| Assay Description Binding affinity to mu opioid receptor |
Bioorg Med Chem Lett 18: 1674-80 (2008)
Article DOI: 10.1016/j.bmcl.2008.01.051 BindingDB Entry DOI: 10.7270/Q2VQ33HQ |
More data for this Ligand-Target Pair | |
Mu-type opioid receptor
(Homo sapiens (Human)) | BDBM50371815
(CHEMBL402116)Show InChI InChI=1S/C15H23NO2/c1-16-11-13-6-3-4-9-15(13,18-2)12-7-5-8-14(17)10-12/h5,7-8,10,13,16-17H,3-4,6,9,11H2,1-2H3/t13-,15+/m1/s1 | PDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 48 | n/a | n/a | n/a | n/a | n/a | n/a |
Sepracor Inc.
Curated by ChEMBL
| Assay Description Binding affinity to mu opioid receptor |
Bioorg Med Chem Lett 18: 1674-80 (2008)
Article DOI: 10.1016/j.bmcl.2008.01.051 BindingDB Entry DOI: 10.7270/Q2VQ33HQ |
More data for this Ligand-Target Pair | |
Mu-type opioid receptor
(Homo sapiens (Human)) | BDBM50371832
(CHEMBL270642)Show InChI InChI=1S/C16H25NO2/c1-17(2)12-14-7-4-5-10-16(14,19-3)13-8-6-9-15(18)11-13/h6,8-9,11,14,18H,4-5,7,10,12H2,1-3H3/t14-,16+/m1/s1 | PDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 56 | n/a | n/a | n/a | n/a | n/a | n/a |
Sepracor Inc.
Curated by ChEMBL
| Assay Description Binding affinity to mu opioid receptor |
Bioorg Med Chem Lett 18: 1674-80 (2008)
Article DOI: 10.1016/j.bmcl.2008.01.051 BindingDB Entry DOI: 10.7270/Q2VQ33HQ |
More data for this Ligand-Target Pair | |
Nitric oxide synthase, brain
(Homo sapiens (Human)) | BDBM50062142
(4,6-Dimethyl-piperidin-(2Z)-ylideneamine | CHEMBL2...)Show InChI InChI=1S/C7H14N2/c1-5-3-6(2)9-7(8)4-5/h5-6H,3-4H2,1-2H3,(H2,8,9) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 60 | n/a | n/a | n/a | n/a | n/a | n/a |
G. D. Searle Research and Development
Curated by ChEMBL
| Assay Description Inhibition of human Neuronal nitric oxide synthase |
J Med Chem 41: 96-101 (1998)
Article DOI: 10.1021/jm9705059 BindingDB Entry DOI: 10.7270/Q2GM86D2 |
More data for this Ligand-Target Pair | |
Nitric oxide synthase, inducible
(Homo sapiens (Human)) | BDBM50062142
(4,6-Dimethyl-piperidin-(2Z)-ylideneamine | CHEMBL2...)Show InChI InChI=1S/C7H14N2/c1-5-3-6(2)9-7(8)4-5/h5-6H,3-4H2,1-2H3,(H2,8,9) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 80 | n/a | n/a | n/a | n/a | n/a | n/a |
G. D. Searle Research and Development
Curated by ChEMBL
| Assay Description Inhibition of human Inducible nitric oxide synthase |
J Med Chem 41: 96-101 (1998)
Article DOI: 10.1021/jm9705059 BindingDB Entry DOI: 10.7270/Q2GM86D2 |
More data for this Ligand-Target Pair | |
Mu-type opioid receptor
(Homo sapiens (Human)) | BDBM50371814
(CHEMBL407563)Show InChI InChI=1S/C15H23NO2/c1-16-11-13-6-3-4-9-15(13,18-2)12-7-5-8-14(17)10-12/h5,7-8,10,13,16-17H,3-4,6,9,11H2,1-2H3/t13-,15+/m0/s1 | PDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 84 | n/a | n/a | n/a | n/a | n/a | n/a |
Sepracor Inc.
Curated by ChEMBL
| Assay Description Binding affinity to mu opioid receptor |
Bioorg Med Chem Lett 18: 1674-80 (2008)
Article DOI: 10.1016/j.bmcl.2008.01.051 BindingDB Entry DOI: 10.7270/Q2VQ33HQ |
More data for this Ligand-Target Pair | |
Mu-type opioid receptor
(Homo sapiens (Human)) | BDBM50371831
(CHEMBL270570)Show InChI InChI=1S/C19H31NO2/c1-4-5-13-22-19(16-10-8-11-18(21)14-16)12-7-6-9-17(19)15-20(2)3/h8,10-11,14,17,21H,4-7,9,12-13,15H2,1-3H3/t17-,19+/m1/s1 | PDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 97 | n/a | n/a | n/a | n/a | n/a | n/a |
Sepracor Inc.
Curated by ChEMBL
| Assay Description Binding affinity to mu opioid receptor |
Bioorg Med Chem Lett 18: 1674-80 (2008)
Article DOI: 10.1016/j.bmcl.2008.01.051 BindingDB Entry DOI: 10.7270/Q2VQ33HQ |
More data for this Ligand-Target Pair | |
Nitric oxide synthase, inducible
(Homo sapiens (Human)) | BDBM50062133
(4-Methyl-piperidin-(2E)-ylideneamine | 4-Methyl-pi...)Show InChI InChI=1S/C6H12N2/c1-5-2-3-8-6(7)4-5/h5H,2-4H2,1H3,(H2,7,8) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL MCE PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 100 | n/a | n/a | n/a | n/a | n/a | n/a |
G. D. Searle Research and Development
Curated by ChEMBL
| Assay Description Inhibition of human Inducible nitric oxide synthase |
J Med Chem 41: 96-101 (1998)
Article DOI: 10.1021/jm9705059 BindingDB Entry DOI: 10.7270/Q2GM86D2 |
More data for this Ligand-Target Pair | |
Sodium-dependent serotonin transporter
(Homo sapiens (Human)) | BDBM50371826
(CHEMBL258140)Show InChI InChI=1S/C20H33NO2/c1-5-6-14-23-20(17-11-9-12-19(15-17)22-4)13-8-7-10-18(20)16-21(2)3/h9,11-12,15,18H,5-8,10,13-14,16H2,1-4H3/t18-,20+/m1/s1 | PDB
KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 110 | n/a | n/a | n/a | n/a | n/a | n/a |
Sepracor Inc.
Curated by ChEMBL
| Assay Description Inhibition of SERT mediated 5-hydroxytryptamine uptake |
Bioorg Med Chem Lett 18: 1674-80 (2008)
Article DOI: 10.1016/j.bmcl.2008.01.051 BindingDB Entry DOI: 10.7270/Q2VQ33HQ |
More data for this Ligand-Target Pair | |
Mu-type opioid receptor
(Homo sapiens (Human)) | BDBM50371824
(CHEMBL272063)Show InChI InChI=1S/C17H27NO2/c1-4-20-17(14-9-7-10-16(19)12-14)11-6-5-8-15(17)13-18(2)3/h7,9-10,12,15,19H,4-6,8,11,13H2,1-3H3/t15-,17+/m1/s1 | PDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 130 | n/a | n/a | n/a | n/a | n/a | n/a |
Sepracor Inc.
Curated by ChEMBL
| Assay Description Binding affinity to mu opioid receptor |
Bioorg Med Chem Lett 18: 1674-80 (2008)
Article DOI: 10.1016/j.bmcl.2008.01.051 BindingDB Entry DOI: 10.7270/Q2VQ33HQ |
More data for this Ligand-Target Pair | |
Mu-type opioid receptor
(Homo sapiens (Human)) | BDBM50371822
(CHEMBL255768)Show InChI InChI=1S/C19H29NO2/c1-20(2)13-17-6-3-4-11-19(17,22-14-15-9-10-15)16-7-5-8-18(21)12-16/h5,7-8,12,15,17,21H,3-4,6,9-11,13-14H2,1-2H3/t17-,19+/m1/s1 | PDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 130 | n/a | n/a | n/a | n/a | n/a | n/a |
Sepracor Inc.
Curated by ChEMBL
| Assay Description Binding affinity to mu opioid receptor |
Bioorg Med Chem Lett 18: 1674-80 (2008)
Article DOI: 10.1016/j.bmcl.2008.01.051 BindingDB Entry DOI: 10.7270/Q2VQ33HQ |
More data for this Ligand-Target Pair | |
Nitric oxide synthase, inducible
(Homo sapiens (Human)) | BDBM50055280
(2-(2-Fluoro-ethyl)-isothiourea | CHEMBL148951)Show InChI InChI=1S/C3H7FN2S/c4-1-2-7-3(5)6/h1-2H2,(H3,5,6) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 140 | n/a | n/a | n/a | n/a | n/a | n/a |
Washington University Medical School
Curated by ChEMBL
| Assay Description The compound was evaluated for the inhibitory potencies using human Inducible nitric oxide synthase (hiNOS) |
J Med Chem 39: 5110-8 (1997)
Article DOI: 10.1021/jm960481q BindingDB Entry DOI: 10.7270/Q29W0DKZ |
More data for this Ligand-Target Pair | |
Nitric oxide synthase, inducible
(Homo sapiens (Human)) | BDBM50064015
(7-Propyl-azepan-(2Z)-ylideneamine; hydrochloride |...)Show InChI InChI=1S/C9H18N2/c1-2-5-8-6-3-4-7-9(10)11-8/h8H,2-7H2,1H3,(H2,10,11) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 160 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description Inhibitory activity evaluated for soluble cell extract of human Inducible nitric oxide synthase and partially purified by DEAE-sepharose chromatograp... |
J Med Chem 41: 1361-6 (1998)
Article DOI: 10.1021/jm9704715 BindingDB Entry DOI: 10.7270/Q2348M29 |
More data for this Ligand-Target Pair | |
Nitric oxide synthase, inducible
(Homo sapiens (Human)) | BDBM50055281
(2-Ethyl-isothiourea | CHEMBL321691 | ETHYLISOTHIOU...)Show InChI InChI=1S/C3H8N2S/c1-2-6-3(4)5/h2H2,1H3,(H3,4,5) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem
Patents
Similars
| PDB Article PubMed
| n/a | n/a | 160 | n/a | n/a | n/a | n/a | n/a | n/a |
Washington University Medical School
Curated by ChEMBL
| Assay Description The compound was evaluated for the inhibitory potencies using human Inducible nitric oxide synthase (hiNOS) |
J Med Chem 39: 5110-8 (1997)
Article DOI: 10.1021/jm960481q BindingDB Entry DOI: 10.7270/Q29W0DKZ |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
Sodium-dependent noradrenaline transporter
(Homo sapiens (Human)) | BDBM50371828
(CHEMBL272533)Show InChI InChI=1S/C17H27NO2/c1-18(2)13-15-8-5-6-11-17(15,20-4)14-9-7-10-16(12-14)19-3/h7,9-10,12,15H,5-6,8,11,13H2,1-4H3/t15-,17+/m1/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 161 | n/a | n/a | n/a | n/a | n/a | n/a |
Sepracor Inc.
Curated by ChEMBL
| Assay Description Inhibition of NET mediated norepinephrine uptake |
Bioorg Med Chem Lett 18: 1674-80 (2008)
Article DOI: 10.1016/j.bmcl.2008.01.051 BindingDB Entry DOI: 10.7270/Q2VQ33HQ |
More data for this Ligand-Target Pair | |
Nitric oxide synthase, inducible
(Homo sapiens (Human)) | BDBM50066778
(5-Ethyl-4-methyl-pyrrolidin-(2E)-ylideneamine; hyd...)Show InChI InChI=1S/C7H14N2/c1-3-6-5(2)4-7(8)9-6/h5-6H,3-4H2,1-2H3,(H2,8,9) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 170 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description Inhibition of cloned (from RNA) human inducible nitric oxide synthase (hiNOS) |
J Med Chem 41: 3675-83 (1998)
Article DOI: 10.1021/jm970840x BindingDB Entry DOI: 10.7270/Q2XP75MP |
More data for this Ligand-Target Pair | |
Nitric oxide synthase, brain
(Homo sapiens (Human)) | BDBM50066778
(5-Ethyl-4-methyl-pyrrolidin-(2E)-ylideneamine; hyd...)Show InChI InChI=1S/C7H14N2/c1-3-6-5(2)4-7(8)9-6/h5-6H,3-4H2,1-2H3,(H2,8,9) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 170 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description Inhibition of cloned (from RNA) human Neuronal nitric oxide synthase |
J Med Chem 41: 3675-83 (1998)
Article DOI: 10.1021/jm970840x BindingDB Entry DOI: 10.7270/Q2XP75MP |
More data for this Ligand-Target Pair | |
Sodium-dependent serotonin transporter
(Homo sapiens (Human)) | BDBM50371833
(CHEMBL403388)Show InChI InChI=1S/C18H29NO2/c1-5-21-18(15-10-8-11-17(13-15)20-4)12-7-6-9-16(18)14-19(2)3/h8,10-11,13,16H,5-7,9,12,14H2,1-4H3/t16-,18+/m1/s1 | PDB
KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 181 | n/a | n/a | n/a | n/a | n/a | n/a |
Sepracor Inc.
Curated by ChEMBL
| Assay Description Inhibition of SERT mediated 5-hydroxytryptamine uptake |
Bioorg Med Chem Lett 18: 1674-80 (2008)
Article DOI: 10.1016/j.bmcl.2008.01.051 BindingDB Entry DOI: 10.7270/Q2VQ33HQ |
More data for this Ligand-Target Pair | |
Mu-type opioid receptor
(Homo sapiens (Human)) | BDBM50371823
(CHEMBL270786)Show InChI InChI=1S/C18H29NO2/c1-4-12-21-18(15-9-7-10-17(20)13-15)11-6-5-8-16(18)14-19(2)3/h7,9-10,13,16,20H,4-6,8,11-12,14H2,1-3H3/t16-,18+/m1/s1 | PDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 190 | n/a | n/a | n/a | n/a | n/a | n/a |
Sepracor Inc.
Curated by ChEMBL
| Assay Description Binding affinity to mu opioid receptor |
Bioorg Med Chem Lett 18: 1674-80 (2008)
Article DOI: 10.1016/j.bmcl.2008.01.051 BindingDB Entry DOI: 10.7270/Q2VQ33HQ |
More data for this Ligand-Target Pair | |
Nitric oxide synthase, inducible
(Homo sapiens (Human)) | BDBM50064018
(7-Allyl-azepan-(2Z)-ylideneamine; hydrochloride | ...)Show InChI InChI=1S/C9H16N2/c1-2-5-8-6-3-4-7-9(10)11-8/h2,8H,1,3-7H2,(H2,10,11) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 190 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description Inhibitory activity evaluated for soluble cell extract of human Inducible nitric oxide synthase and partially purified by DEAE-sepharose chromatograp... |
J Med Chem 41: 1361-6 (1998)
Article DOI: 10.1021/jm9704715 BindingDB Entry DOI: 10.7270/Q2348M29 |
More data for this Ligand-Target Pair | |
Mu-type opioid receptor
(Homo sapiens (Human)) | BDBM50371820
(CHEMBL257264)Show InChI InChI=1S/C17H27NO3/c1-18(2)13-15-6-3-4-9-17(15,21-11-10-19)14-7-5-8-16(20)12-14/h5,7-8,12,15,19-20H,3-4,6,9-11,13H2,1-2H3/t15-,17+/m1/s1 | PDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 190 | n/a | n/a | n/a | n/a | n/a | n/a |
Sepracor Inc.
Curated by ChEMBL
| Assay Description Binding affinity to mu opioid receptor |
Bioorg Med Chem Lett 18: 1674-80 (2008)
Article DOI: 10.1016/j.bmcl.2008.01.051 BindingDB Entry DOI: 10.7270/Q2VQ33HQ |
More data for this Ligand-Target Pair | |
Nitric oxide synthase, brain
(Homo sapiens (Human)) | BDBM50062133
(4-Methyl-piperidin-(2E)-ylideneamine | 4-Methyl-pi...)Show InChI InChI=1S/C6H12N2/c1-5-2-3-8-6(7)4-5/h5H,2-4H2,1H3,(H2,7,8) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL MCE PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 200 | n/a | n/a | n/a | n/a | n/a | n/a |
G. D. Searle Research and Development
Curated by ChEMBL
| Assay Description Inhibition of human Neuronal nitric oxide synthase |
J Med Chem 41: 96-101 (1998)
Article DOI: 10.1021/jm9705059 BindingDB Entry DOI: 10.7270/Q2GM86D2 |
More data for this Ligand-Target Pair | |
Nitric oxide synthase, inducible
(Homo sapiens (Human)) | BDBM50062132
(6-Propyl-piperidin-(2Z)-ylideneamine | CHEMBL6760)Show InChI InChI=1S/C8H16N2/c1-2-4-7-5-3-6-8(9)10-7/h7H,2-6H2,1H3,(H2,9,10) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 200 | n/a | n/a | n/a | n/a | n/a | n/a |
G. D. Searle Research and Development
Curated by ChEMBL
| Assay Description Inhibition of human Inducible nitric oxide synthase |
J Med Chem 41: 96-101 (1998)
Article DOI: 10.1021/jm9705059 BindingDB Entry DOI: 10.7270/Q2GM86D2 |
More data for this Ligand-Target Pair | |
Nitric oxide synthase, inducible
(Homo sapiens (Human)) | BDBM50066775
(5-Pentyl-4-trifluoromethyl-pyrrolidin-(2E)-ylidene...)Show InChI InChI=1S/C10H17F3N2/c1-2-3-4-5-8-7(10(11,12)13)6-9(14)15-8/h7-8H,2-6H2,1H3,(H2,14,15) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 230 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description Inhibition of cloned (from RNA) human inducible nitric oxide synthase (hiNOS) |
J Med Chem 41: 3675-83 (1998)
Article DOI: 10.1021/jm970840x BindingDB Entry DOI: 10.7270/Q2XP75MP |
More data for this Ligand-Target Pair | |
Nitric oxide synthase, inducible
(Homo sapiens (Human)) | BDBM50066785
(4-Methyl-5-propyl-pyrrolidin-(2E)-ylideneamine; hy...)Show InChI InChI=1S/C8H16N2/c1-3-4-7-6(2)5-8(9)10-7/h6-7H,3-5H2,1-2H3,(H2,9,10) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 300 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description Inhibition of cloned (from RNA) human inducible nitric oxide synthase (hiNOS) |
J Med Chem 41: 3675-83 (1998)
Article DOI: 10.1021/jm970840x BindingDB Entry DOI: 10.7270/Q2XP75MP |
More data for this Ligand-Target Pair | |
Nitric oxide synthase, endothelial
(Homo sapiens (Human)) | BDBM50062142
(4,6-Dimethyl-piperidin-(2Z)-ylideneamine | CHEMBL2...)Show InChI InChI=1S/C7H14N2/c1-5-3-6(2)9-7(8)4-5/h5-6H,3-4H2,1-2H3,(H2,8,9) | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 300 | n/a | n/a | n/a | n/a | n/a | n/a |
G. D. Searle Research and Development
Curated by ChEMBL
| Assay Description inhibition of human endothelial constitutive Endothelial nitric oxide synthase (heNOS) |
J Med Chem 41: 96-101 (1998)
Article DOI: 10.1021/jm9705059 BindingDB Entry DOI: 10.7270/Q2GM86D2 |
More data for this Ligand-Target Pair | |
Nitric oxide synthase, inducible
(Homo sapiens (Human)) | BDBM50066774
(4-Methyl-5-pentyl-pyrrolidin-(2E)-ylideneamine; hy...)Show InChI InChI=1S/C10H20N2/c1-3-4-5-6-9-8(2)7-10(11)12-9/h8-9H,3-7H2,1-2H3,(H2,11,12) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 360 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description Inhibition of cloned (from RNA) human inducible nitric oxide synthase (hiNOS) |
J Med Chem 41: 3675-83 (1998)
Article DOI: 10.1021/jm970840x BindingDB Entry DOI: 10.7270/Q2XP75MP |
More data for this Ligand-Target Pair | |
Nitric oxide synthase, inducible
(Homo sapiens (Human)) | BDBM50066774
(4-Methyl-5-pentyl-pyrrolidin-(2E)-ylideneamine; hy...)Show InChI InChI=1S/C10H20N2/c1-3-4-5-6-9-8(2)7-10(11)12-9/h8-9H,3-7H2,1-2H3,(H2,11,12) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 360 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description Inhibition of cloned (from RNA) human inducible nitric oxide synthase (hiNOS) |
J Med Chem 41: 3675-83 (1998)
Article DOI: 10.1021/jm970840x BindingDB Entry DOI: 10.7270/Q2XP75MP |
More data for this Ligand-Target Pair | |
Nitric oxide synthase, brain
(Homo sapiens (Human)) | BDBM50066785
(4-Methyl-5-propyl-pyrrolidin-(2E)-ylideneamine; hy...)Show InChI InChI=1S/C8H16N2/c1-3-4-7-6(2)5-8(9)10-7/h6-7H,3-5H2,1-2H3,(H2,9,10) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 390 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description Inhibition of cloned (from RNA) human Neuronal nitric oxide synthase |
J Med Chem 41: 3675-83 (1998)
Article DOI: 10.1021/jm970840x BindingDB Entry DOI: 10.7270/Q2XP75MP |
More data for this Ligand-Target Pair | |
Nitric oxide synthase, brain
(Homo sapiens (Human)) | BDBM50062137
(6-Methyl-piperidin-(2Z)-ylideneamine | CHEMBL26567...)Show InChI InChI=1S/C6H12N2/c1-5-3-2-4-6(7)8-5/h5H,2-4H2,1H3,(H2,7,8) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 400 | n/a | n/a | n/a | n/a | n/a | n/a |
G. D. Searle Research and Development
Curated by ChEMBL
| Assay Description Inhibition of human Neuronal nitric oxide synthase |
J Med Chem 41: 96-101 (1998)
Article DOI: 10.1021/jm9705059 BindingDB Entry DOI: 10.7270/Q2GM86D2 |
More data for this Ligand-Target Pair | |
Nitric oxide synthase, brain
(Homo sapiens (Human)) | BDBM50064015
(7-Propyl-azepan-(2Z)-ylideneamine; hydrochloride |...)Show InChI InChI=1S/C9H18N2/c1-2-5-8-6-3-4-7-9(10)11-8/h8H,2-7H2,1H3,(H2,10,11) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 460 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description Inhibitory activity evaluated from soluble cell extract of human Neuronal nitric oxide synthase and partially purified by DEAE-sepharose chromatograp... |
J Med Chem 41: 1361-6 (1998)
Article DOI: 10.1021/jm9704715 BindingDB Entry DOI: 10.7270/Q2348M29 |
More data for this Ligand-Target Pair | |
Nitric oxide synthase, inducible
(Homo sapiens (Human)) | BDBM50062131
(6-Trifluoromethyl-piperidin-(2Z)-ylideneamine | CH...)Show InChI InChI=1S/C6H9F3N2/c7-6(8,9)4-2-1-3-5(10)11-4/h4H,1-3H2,(H2,10,11) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
| Article PubMed
| n/a | n/a | 500 | n/a | n/a | n/a | n/a | n/a | n/a |
G. D. Searle Research and Development
Curated by ChEMBL
| Assay Description Inhibition of human Inducible nitric oxide synthase |
J Med Chem 41: 96-101 (1998)
Article DOI: 10.1021/jm9705059 BindingDB Entry DOI: 10.7270/Q2GM86D2 |
More data for this Ligand-Target Pair | |
Nitric oxide synthase, brain
(Homo sapiens (Human)) | BDBM50062131
(6-Trifluoromethyl-piperidin-(2Z)-ylideneamine | CH...)Show InChI InChI=1S/C6H9F3N2/c7-6(8,9)4-2-1-3-5(10)11-4/h4H,1-3H2,(H2,10,11) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
| Article PubMed
| n/a | n/a | 500 | n/a | n/a | n/a | n/a | n/a | n/a |
G. D. Searle Research and Development
Curated by ChEMBL
| Assay Description Inhibition of human Neuronal nitric oxide synthase |
J Med Chem 41: 96-101 (1998)
Article DOI: 10.1021/jm9705059 BindingDB Entry DOI: 10.7270/Q2GM86D2 |
More data for this Ligand-Target Pair | |
Nitric oxide synthase, inducible
(Homo sapiens (Human)) | BDBM50064011
(7-Butyl-azepan-(2Z)-ylideneamine; hydrochloride | ...)Show InChI InChI=1S/C10H20N2/c1-2-3-6-9-7-4-5-8-10(11)12-9/h9H,2-8H2,1H3,(H2,11,12) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 500 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description Inhibitory activity evaluated for soluble cell extract of human Inducible nitric oxide synthase and partially purified by DEAE-sepharose chromatograp... |
J Med Chem 41: 1361-6 (1998)
Article DOI: 10.1021/jm9704715 BindingDB Entry DOI: 10.7270/Q2348M29 |
More data for this Ligand-Target Pair | |
Nitric oxide synthase, inducible
(Mus musculus (mouse)) | BDBM50225106
((2S)-2-amino-5-{[(E)-amino(nitroimino)methyl]amino...)Show SMILES N[C@@H](CCCNC(N)=N[N+]([O-])=O)C(O)=O |r,w:8.8| Show InChI InChI=1S/C6H13N5O4/c7-4(5(12)13)2-1-3-9-6(8)10-11(14)15/h4H,1-3,7H2,(H,12,13)(H3,8,9,10)/t4-/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| CHEMBL MMDB PC cid PC sid PDB UniChem
Patents
Similars
| PubMed
| n/a | n/a | 500 | n/a | n/a | n/a | n/a | n/a | n/a |
G. D. Searle Research and Development
Curated by ChEMBL
| Assay Description Tested for inhibition of mouse inducible nitric oxide synthase |
J Med Chem 37: 3886-8 (1994)
BindingDB Entry DOI: 10.7270/Q29P328V |
More data for this Ligand-Target Pair | |
Nitric oxide synthase, brain
(Homo sapiens (Human)) | BDBM50062132
(6-Propyl-piperidin-(2Z)-ylideneamine | CHEMBL6760)Show InChI InChI=1S/C8H16N2/c1-2-4-7-5-3-6-8(9)10-7/h7H,2-6H2,1H3,(H2,9,10) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 500 | n/a | n/a | n/a | n/a | n/a | n/a |
G. D. Searle Research and Development
Curated by ChEMBL
| Assay Description Inhibition of human Neuronal nitric oxide synthase |
J Med Chem 41: 96-101 (1998)
Article DOI: 10.1021/jm9705059 BindingDB Entry DOI: 10.7270/Q2GM86D2 |
More data for this Ligand-Target Pair | |
Nitric oxide synthase, brain
(Homo sapiens (Human)) | BDBM50049252
(2-Amino-5-(N-nitro-guanidino)-pentanoic acid | CHE...)Show InChI InChI=1S/C6H13N5O4/c7-4(5(12)13)2-1-3-10(6(8)9)11(14)15/h4H,1-3,7H2,(H3,8,9)(H,12,13)/t4-/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
| Article PubMed
| n/a | n/a | 500 | n/a | n/a | n/a | n/a | n/a | n/a |
G. D. Searle Research and Development
Curated by ChEMBL
| Assay Description Inhibitory activity against human Neuronal nitric oxide synthase |
J Med Chem 39: 669-72 (1996)
Article DOI: 10.1021/jm950766n BindingDB Entry DOI: 10.7270/Q261110M |
More data for this Ligand-Target Pair | |
Nitric oxide synthase, inducible
(Homo sapiens (Human)) | BDBM50062137
(6-Methyl-piperidin-(2Z)-ylideneamine | CHEMBL26567...)Show InChI InChI=1S/C6H12N2/c1-5-3-2-4-6(7)8-5/h5H,2-4H2,1H3,(H2,7,8) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 500 | n/a | n/a | n/a | n/a | n/a | n/a |
G. D. Searle Research and Development
Curated by ChEMBL
| Assay Description Inhibition of human Inducible nitric oxide synthase |
J Med Chem 41: 96-101 (1998)
Article DOI: 10.1021/jm9705059 BindingDB Entry DOI: 10.7270/Q2GM86D2 |
More data for this Ligand-Target Pair | |
Nitric oxide synthase, endothelial
(Homo sapiens (Human)) | BDBM50225106
((2S)-2-amino-5-{[(E)-amino(nitroimino)methyl]amino...)Show SMILES N[C@@H](CCCNC(N)=N[N+]([O-])=O)C(O)=O |r,w:8.8| Show InChI InChI=1S/C6H13N5O4/c7-4(5(12)13)2-1-3-9-6(8)10-11(14)15/h4H,1-3,7H2,(H,12,13)(H3,8,9,10)/t4-/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL MMDB PC cid PC sid PDB UniChem
Patents
Similars
| PDB Article PubMed
| n/a | n/a | 500 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description Inhibition of cloned (from RNA) human endothelial constitutive Endothelial nitric oxide synthase (heNOS) |
J Med Chem 41: 3675-83 (1998)
Article DOI: 10.1021/jm970840x BindingDB Entry DOI: 10.7270/Q2XP75MP |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
Nitric oxide synthase, brain
(Homo sapiens (Human)) | BDBM50225106
((2S)-2-amino-5-{[(E)-amino(nitroimino)methyl]amino...)Show SMILES N[C@@H](CCCNC(N)=N[N+]([O-])=O)C(O)=O |r,w:8.8| Show InChI InChI=1S/C6H13N5O4/c7-4(5(12)13)2-1-3-9-6(8)10-11(14)15/h4H,1-3,7H2,(H,12,13)(H3,8,9,10)/t4-/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL MMDB PC cid PC sid PDB UniChem
Patents
Similars
| PDB Article PubMed
| n/a | n/a | 500 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description Inhibition of cloned (from RNA) human Neuronal nitric oxide synthase |
J Med Chem 41: 3675-83 (1998)
Article DOI: 10.1021/jm970840x BindingDB Entry DOI: 10.7270/Q2XP75MP |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
Nitric oxide synthase, endothelial
(Homo sapiens (Human)) | BDBM50049252
(2-Amino-5-(N-nitro-guanidino)-pentanoic acid | CHE...)Show InChI InChI=1S/C6H13N5O4/c7-4(5(12)13)2-1-3-10(6(8)9)11(14)15/h4H,1-3,7H2,(H3,8,9)(H,12,13)/t4-/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
| Article PubMed
| n/a | n/a | 500 | n/a | n/a | n/a | n/a | n/a | n/a |
G. D. Searle Research and Development
Curated by ChEMBL
| Assay Description Inhibitory activity against human Endothelial nitric oxide synthase |
J Med Chem 39: 669-72 (1996)
Article DOI: 10.1021/jm950766n BindingDB Entry DOI: 10.7270/Q261110M |
More data for this Ligand-Target Pair | |
Sodium-dependent noradrenaline transporter
(Homo sapiens (Human)) | BDBM50371832
(CHEMBL270642)Show InChI InChI=1S/C16H25NO2/c1-17(2)12-14-7-4-5-10-16(14,19-3)13-8-6-9-15(18)11-13/h6,8-9,11,14,18H,4-5,7,10,12H2,1-3H3/t14-,16+/m1/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 525 | n/a | n/a | n/a | n/a | n/a | n/a |
Sepracor Inc.
Curated by ChEMBL
| Assay Description Inhibition of NET mediated norepinephrine uptake |
Bioorg Med Chem Lett 18: 1674-80 (2008)
Article DOI: 10.1016/j.bmcl.2008.01.051 BindingDB Entry DOI: 10.7270/Q2VQ33HQ |
More data for this Ligand-Target Pair | |
Nitric oxide synthase, inducible
(Mus musculus (mouse)) | BDBM50064015
(7-Propyl-azepan-(2Z)-ylideneamine; hydrochloride |...)Show InChI InChI=1S/C9H18N2/c1-2-5-8-6-3-4-7-9(10)11-8/h8H,2-7H2,1H3,(H2,10,11) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 600 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description The ability of compound to inhibit mouse Inducible nitric oxide synthase in LPS stimulated mouse RAW cells was determined |
J Med Chem 41: 1361-6 (1998)
Article DOI: 10.1021/jm9704715 BindingDB Entry DOI: 10.7270/Q2348M29 |
More data for this Ligand-Target Pair | |
Nitric oxide synthase, inducible
(Mus musculus (mouse)) | BDBM50064018
(7-Allyl-azepan-(2Z)-ylideneamine; hydrochloride | ...)Show InChI InChI=1S/C9H16N2/c1-2-5-8-6-3-4-7-9(10)11-8/h2,8H,1,3-7H2,(H2,10,11) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 600 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description The ability of compound to inhibit mouse Inducible nitric oxide synthase in LPS stimulated mouse RAW cells was determined |
J Med Chem 41: 1361-6 (1998)
Article DOI: 10.1021/jm9704715 BindingDB Entry DOI: 10.7270/Q2348M29 |
More data for this Ligand-Target Pair | |
Nitric oxide synthase, endothelial
(Homo sapiens (Human)) | BDBM50062137
(6-Methyl-piperidin-(2Z)-ylideneamine | CHEMBL26567...)Show InChI InChI=1S/C6H12N2/c1-5-3-2-4-6(7)8-5/h5H,2-4H2,1H3,(H2,7,8) | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 600 | n/a | n/a | n/a | n/a | n/a | n/a |
G. D. Searle Research and Development
Curated by ChEMBL
| Assay Description inhibition of human endothelial constitutive Endothelial nitric oxide synthase (heNOS) |
J Med Chem 41: 96-101 (1998)
Article DOI: 10.1021/jm9705059 BindingDB Entry DOI: 10.7270/Q2GM86D2 |
More data for this Ligand-Target Pair | |