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Compile Data Set for Download or QSAR

Found 192 hits with Last Name = 'deltent' and Initial = 'mf'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Histamine H3 receptor


(Homo sapiens (Human))
BDBM50150945
PNG
(CHEBI:81390 | Immepip)
Show SMILES C(C1CCNCC1)c1c[nH]cn1
Show InChI InChI=1S/C9H15N3/c1-3-10-4-2-8(1)5-9-6-11-7-12-9/h6-8,10H,1-5H2,(H,11,12)
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0.479n/an/an/an/an/an/an/an/a



Vrije Universiteit

Curated by ChEMBL


Assay Description
Inhibitory activity measured by [3H]- N alpha- methyl-histamine binding to membranes of SK-N-MC cells expressing the human Histamine H3 receptor


J Med Chem 46: 5445-57 (2003)


Article DOI: 10.1021/jm030905y
BindingDB Entry DOI: 10.7270/Q2FN18X0
More data for this
Ligand-Target Pair
Histamine H3 receptor


(Homo sapiens (Human))
BDBM50474424
PNG
(CHEMBL153051)
Show SMILES [H][C@@]1(Cc2c[nH]cn2)CCNC1
Show InChI InChI=1S/C8H13N3/c1-2-9-4-7(1)3-8-5-10-6-11-8/h5-7,9H,1-4H2,(H,10,11)/t7-/m0/s1
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1.40n/an/an/an/an/an/an/an/a



Vrije Universiteit

Curated by ChEMBL


Assay Description
Inhibitory activity measured by [3H]- N alpha- methyl-histamine binding to membranes of SK-N-MC cells expressing the human Histamine H3 receptor


J Med Chem 46: 5445-57 (2003)


Article DOI: 10.1021/jm030905y
BindingDB Entry DOI: 10.7270/Q2FN18X0
More data for this
Ligand-Target Pair
Histamine H3 receptor


(Homo sapiens (Human))
BDBM50474427
PNG
(CHEMBL153061)
Show SMILES C(C1CCNC1)c1c[nH]cn1
Show InChI InChI=1S/C8H13N3/c1-2-9-4-7(1)3-8-5-10-6-11-8/h5-7,9H,1-4H2,(H,10,11)
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3.60n/an/an/an/an/an/an/an/a



Vrije Universiteit

Curated by ChEMBL


Assay Description
Inhibitory activity measured by [3H]- N alpha- methyl-histamine binding to membranes of SK-N-MC cells expressing the human Histamine H3 receptor


J Med Chem 46: 5445-57 (2003)


Article DOI: 10.1021/jm030905y
BindingDB Entry DOI: 10.7270/Q2FN18X0
More data for this
Ligand-Target Pair
Histamine H3 receptor


(Homo sapiens (Human))
BDBM50474428
PNG
(CHEMBL152936)
Show SMILES C=C(C1CCNCC1)c1c[nH]cn1
Show InChI InChI=1S/C10H15N3/c1-8(10-6-12-7-13-10)9-2-4-11-5-3-9/h6-7,9,11H,1-5H2,(H,12,13)
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4n/an/an/an/an/an/an/an/a



Vrije Universiteit

Curated by ChEMBL


Assay Description
Inhibitory activity measured by [3H]- N alpha- methyl-histamine binding to membranes of SK-N-MC cells expressing the human Histamine H3 receptor


J Med Chem 46: 5445-57 (2003)


Article DOI: 10.1021/jm030905y
BindingDB Entry DOI: 10.7270/Q2FN18X0
More data for this
Ligand-Target Pair
Histamine H3 receptor


(Homo sapiens (Human))
BDBM50170164
PNG
(Imbutamine)
Show SMILES NCCCCc1c[nH]cn1
Show InChI InChI=1S/C7H13N3/c8-4-2-1-3-7-5-9-6-10-7/h5-6H,1-4,8H2,(H,9,10)
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4.10n/an/an/an/an/an/an/an/a



Vrije Universiteit

Curated by ChEMBL


Assay Description
Inhibitory activity measured by [3H]- N alpha- methyl-histamine binding to membranes of SK-N-MC cells expressing the human Histamine H3 receptor


J Med Chem 46: 5445-57 (2003)


Article DOI: 10.1021/jm030905y
BindingDB Entry DOI: 10.7270/Q2FN18X0
More data for this
Ligand-Target Pair
Histamine H3 receptor


(Homo sapiens (Human))
BDBM50215536
PNG
((R)-Alpha-Methylhistamine | CHEBI:73337 | CHEMBL26...)
Show SMILES C[C@@H](N)Cc1c[nH]cn1 |r|
Show InChI InChI=1S/C6H11N3/c1-5(7)2-6-3-8-4-9-6/h3-5H,2,7H2,1H3,(H,8,9)/t5-/m1/s1
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4.40n/an/an/an/an/an/an/an/a



Vrije Universiteit

Curated by ChEMBL


Assay Description
Inhibitory activity measured by [3H]- N alpha- methyl-histamine binding to membranes of SK-N-MC cells expressing the human Histamine H3 receptor


J Med Chem 46: 5445-57 (2003)


Article DOI: 10.1021/jm030905y
BindingDB Entry DOI: 10.7270/Q2FN18X0
More data for this
Ligand-Target Pair
Histamine H3 receptor


(Homo sapiens (Human))
BDBM50409817
PNG
(CHEMBL78498 | VUF-5681)
Show SMILES C(CC1CCNCC1)Cc1cnc[nH]1
Show InChI InChI=1S/C11H19N3/c1(3-11-8-13-9-14-11)2-10-4-6-12-7-5-10/h8-10,12H,1-7H2,(H,13,14)
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4.5n/an/an/an/an/an/an/an/a



Vrije Universiteit

Curated by ChEMBL


Assay Description
Inhibitory activity measured by [3H]- N alpha- methyl-histamine binding to membranes of SK-N-MC cells expressing the human Histamine H3 receptor


J Med Chem 46: 5445-57 (2003)


Article DOI: 10.1021/jm030905y
BindingDB Entry DOI: 10.7270/Q2FN18X0
More data for this
Ligand-Target Pair
Histamine H3 receptor


(Homo sapiens (Human))
BDBM50474426
PNG
(Impentamine)
Show SMILES NCCCCCc1c[nH]cn1
Show InChI InChI=1S/C8H15N3/c9-5-3-1-2-4-8-6-10-7-11-8/h6-7H,1-5,9H2,(H,10,11)
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5.10n/an/an/an/an/an/an/an/a



Vrije Universiteit

Curated by ChEMBL


Assay Description
Inhibitory activity measured by [3H]- N alpha- methyl-histamine binding to membranes of SK-N-MC cells expressing the human Histamine H3 receptor


J Med Chem 46: 5445-57 (2003)


Article DOI: 10.1021/jm030905y
BindingDB Entry DOI: 10.7270/Q2FN18X0
More data for this
Ligand-Target Pair
Histamine H3 receptor


(Homo sapiens (Human))
BDBM50474433
PNG
(CHEMBL440730)
Show SMILES [H][C@]1(Cc2c[nH]cn2)CCNC1
Show InChI InChI=1S/C8H13N3/c1-2-9-4-7(1)3-8-5-10-6-11-8/h5-7,9H,1-4H2,(H,10,11)/t7-/m1/s1
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5.20n/an/an/an/an/an/an/an/a



Vrije Universiteit

Curated by ChEMBL


Assay Description
Inhibitory activity measured by [3H]- N alpha- methyl-histamine binding to membranes of SK-N-MC cells expressing the human Histamine H3 receptor


J Med Chem 46: 5445-57 (2003)


Article DOI: 10.1021/jm030905y
BindingDB Entry DOI: 10.7270/Q2FN18X0
More data for this
Ligand-Target Pair
Histamine H3 receptor


(Homo sapiens (Human))
BDBM50474425
PNG
(CHEMBL356666)
Show SMILES C1CC(CCN1)=Cc1c[nH]cn1 |(1.48,1.21,;-.04,1.44,;-.6,2.89,;.37,4.08,;1.9,3.85,;2.46,2.41,;-2.12,3.13,;-3.09,1.91,;-4.62,1.98,;-5.16,.53,;-3.97,-.4,;-2.68,.46,)|
Show InChI InChI=1S/C9H13N3/c1-3-10-4-2-8(1)5-9-6-11-7-12-9/h5-7,10H,1-4H2,(H,11,12)
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5.90n/an/an/an/an/an/an/an/a



Vrije Universiteit

Curated by ChEMBL


Assay Description
Inhibitory activity measured by [3H]- N alpha- methyl-histamine binding to membranes of SK-N-MC cells expressing the human Histamine H3 receptor


J Med Chem 46: 5445-57 (2003)


Article DOI: 10.1021/jm030905y
BindingDB Entry DOI: 10.7270/Q2FN18X0
More data for this
Ligand-Target Pair
Histamine H3 receptor


(Homo sapiens (Human))
BDBM50127605
PNG
((1S,2S)-2-(1H-Imidazol-4-yl)-cyclopropylamine | (1...)
Show SMILES N[C@H]1C[C@@H]1c1cnc[nH]1
Show InChI InChI=1S/C6H9N3/c7-5-1-4(5)6-2-8-3-9-6/h2-5H,1,7H2,(H,8,9)/t4-,5-/m0/s1
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9.30n/an/an/an/an/an/an/an/a



Vrije Universiteit

Curated by ChEMBL


Assay Description
Inhibitory activity measured by [3H]- N alpha- methyl-histamine binding to membranes of SK-N-MC cells expressing the human Histamine H3 receptor


J Med Chem 46: 5445-57 (2003)


Article DOI: 10.1021/jm030905y
BindingDB Entry DOI: 10.7270/Q2FN18X0
More data for this
Ligand-Target Pair
Histamine H3 receptor


(Homo sapiens (Human))
BDBM50121205
PNG
(CHEBI:18295 | Histamine)
Show SMILES NCCc1c[nH]cn1
Show InChI InChI=1S/C5H9N3/c6-2-1-5-3-7-4-8-5/h3-4H,1-2,6H2,(H,7,8)
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9.30n/an/an/an/an/an/an/an/a



Vrije Universiteit

Curated by ChEMBL


Assay Description
Inhibitory activity measured by [3H]- N alpha- methyl-histamine binding to membranes of SK-N-MC cells expressing the human Histamine H3 receptor


J Med Chem 46: 5445-57 (2003)


Article DOI: 10.1021/jm030905y
BindingDB Entry DOI: 10.7270/Q2FN18X0
More data for this
Ligand-Target Pair
Histamine H3 receptor


(Homo sapiens (Human))
BDBM50407522
PNG
(CHEMBL554031)
Show SMILES NCCCCCCc1cnc[nH]1
Show InChI InChI=1S/C9H17N3/c10-6-4-2-1-3-5-9-7-11-8-12-9/h7-8H,1-6,10H2,(H,11,12)
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10n/an/an/an/an/an/an/an/a



Vrije Universiteit

Curated by ChEMBL


Assay Description
Inhibitory activity measured by [3H]- N alpha- methyl-histamine binding to membranes of SK-N-MC cells expressing the human Histamine H3 receptor


J Med Chem 46: 5445-57 (2003)


Article DOI: 10.1021/jm030905y
BindingDB Entry DOI: 10.7270/Q2FN18X0
More data for this
Ligand-Target Pair
Histamine H4 receptor


(Homo sapiens (Human))
BDBM50121205
PNG
(CHEBI:18295 | Histamine)
Show SMILES NCCc1c[nH]cn1
Show InChI InChI=1S/C5H9N3/c6-2-1-5-3-7-4-8-5/h3-4H,1-2,6H2,(H,7,8)
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14n/an/an/an/an/an/an/an/a



Vrije Universiteit

Curated by ChEMBL


Assay Description
Inhibition of [3H]-histamine binding to membranes of SK-N-MC cells expressing the human Histamine H4 receptor


J Med Chem 46: 5445-57 (2003)


Article DOI: 10.1021/jm030905y
BindingDB Entry DOI: 10.7270/Q2FN18X0
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
Histamine H4 receptor


(Homo sapiens (Human))
BDBM50170164
PNG
(Imbutamine)
Show SMILES NCCCCc1c[nH]cn1
Show InChI InChI=1S/C7H13N3/c8-4-2-1-3-7-5-9-6-10-7/h5-6H,1-4,8H2,(H,9,10)
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14.5n/an/an/an/an/an/an/an/a



Vrije Universiteit

Curated by ChEMBL


Assay Description
Inhibitory activity measured by [3H]- N alpha- methyl-histamine binding to membranes of SK-N-MC cells expressing the human Histamine H4 receptor


J Med Chem 46: 5445-57 (2003)


Article DOI: 10.1021/jm030905y
BindingDB Entry DOI: 10.7270/Q2FN18X0
More data for this
Ligand-Target Pair
Histamine H3 receptor


(Homo sapiens (Human))
BDBM50409216
PNG
(CHEMBL150701)
Show SMILES C(Cc1cnc[nH]1)C1CCNCC1
Show InChI InChI=1S/C10H17N3/c1(2-10-7-12-8-13-10)9-3-5-11-6-4-9/h7-9,11H,1-6H2,(H,12,13)
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20n/an/an/an/an/an/an/an/a



Vrije Universiteit

Curated by ChEMBL


Assay Description
Inhibitory activity measured by [3H]- N alpha- methyl-histamine binding to membranes of SK-N-MC cells expressing the human Histamine H3 receptor


J Med Chem 46: 5445-57 (2003)


Article DOI: 10.1021/jm030905y
BindingDB Entry DOI: 10.7270/Q2FN18X0
More data for this
Ligand-Target Pair
Histamine H4 receptor


(Homo sapiens (Human))
BDBM50150945
PNG
(CHEBI:81390 | Immepip)
Show SMILES C(C1CCNCC1)c1c[nH]cn1
Show InChI InChI=1S/C9H15N3/c1-3-10-4-2-8(1)5-9-6-11-7-12-9/h6-8,10H,1-5H2,(H,11,12)
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21.9n/an/an/an/an/an/an/an/a



Vrije Universiteit

Curated by ChEMBL


Assay Description
Inhibitory activity measured by [3H]- N alpha- methyl-histamine binding to membranes of SK-N-MC cells expressing the human Histamine H4 receptor


J Med Chem 46: 5445-57 (2003)


Article DOI: 10.1021/jm030905y
BindingDB Entry DOI: 10.7270/Q2FN18X0
More data for this
Ligand-Target Pair
Histamine H4 receptor


(Homo sapiens (Human))
BDBM50474435
PNG
(Homohistamine)
Show SMILES NCCCc1c[nH]cn1
Show InChI InChI=1S/C6H11N3/c7-3-1-2-6-4-8-5-9-6/h4-5H,1-3,7H2,(H,8,9)
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34.7n/an/an/an/an/an/an/an/a



Vrije Universiteit

Curated by ChEMBL


Assay Description
Inhibitory activity measured by [3H]- N alpha- methyl-histamine binding to membranes of SK-N-MC cells expressing the human Histamine H4 receptor


J Med Chem 46: 5445-57 (2003)


Article DOI: 10.1021/jm030905y
BindingDB Entry DOI: 10.7270/Q2FN18X0
More data for this
Ligand-Target Pair
Histamine H3 receptor


(Homo sapiens (Human))
BDBM50474423
PNG
(CHEMBL153284)
Show SMILES NCC1CC1c1c[nH]cn1
Show InChI InChI=1S/C7H11N3/c8-2-5-1-6(5)7-3-9-4-10-7/h3-6H,1-2,8H2,(H,9,10)
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35n/an/an/an/an/an/an/an/a



Vrije Universiteit

Curated by ChEMBL


Assay Description
Inhibitory activity measured by [3H]- N alpha- methyl-histamine binding to membranes of SK-N-MC cells expressing the human Histamine H3 receptor


J Med Chem 46: 5445-57 (2003)


Article DOI: 10.1021/jm030905y
BindingDB Entry DOI: 10.7270/Q2FN18X0
More data for this
Ligand-Target Pair
Histamine H4 receptor


(Homo sapiens (Human))
BDBM50474433
PNG
(CHEMBL440730)
Show SMILES [H][C@]1(Cc2c[nH]cn2)CCNC1
Show InChI InChI=1S/C8H13N3/c1-2-9-4-7(1)3-8-5-10-6-11-8/h5-7,9H,1-4H2,(H,10,11)/t7-/m1/s1
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37.2n/an/an/an/an/an/an/an/a



Vrije Universiteit

Curated by ChEMBL


Assay Description
Inhibitory activity measured by [3H]- N alpha- methyl-histamine binding to membranes of SK-N-MC cells expressing the human Histamine H4 receptor


J Med Chem 46: 5445-57 (2003)


Article DOI: 10.1021/jm030905y
BindingDB Entry DOI: 10.7270/Q2FN18X0
More data for this
Ligand-Target Pair
Histamine H3 receptor


(Homo sapiens (Human))
BDBM50474435
PNG
(Homohistamine)
Show SMILES NCCCc1c[nH]cn1
Show InChI InChI=1S/C6H11N3/c7-3-1-2-6-4-8-5-9-6/h4-5H,1-3,7H2,(H,8,9)
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49n/an/an/an/an/an/an/an/a



Vrije Universiteit

Curated by ChEMBL


Assay Description
Inhibitory activity measured by [3H]- N alpha- methyl-histamine binding to membranes of SK-N-MC cells expressing the human Histamine H3 receptor


J Med Chem 46: 5445-57 (2003)


Article DOI: 10.1021/jm030905y
BindingDB Entry DOI: 10.7270/Q2FN18X0
More data for this
Ligand-Target Pair
Histamine H4 receptor


(Homo sapiens (Human))
BDBM50474427
PNG
(CHEMBL153061)
Show SMILES C(C1CCNC1)c1c[nH]cn1
Show InChI InChI=1S/C8H13N3/c1-2-9-4-7(1)3-8-5-10-6-11-8/h5-7,9H,1-4H2,(H,10,11)
PDB

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51.3n/an/an/an/an/an/an/an/a



Vrije Universiteit

Curated by ChEMBL


Assay Description
Inhibitory activity measured by [3H]- N alpha- methyl-histamine binding to membranes of SK-N-MC cells expressing the human Histamine H4 receptor


J Med Chem 46: 5445-57 (2003)


Article DOI: 10.1021/jm030905y
BindingDB Entry DOI: 10.7270/Q2FN18X0
More data for this
Ligand-Target Pair
Histamine H3 receptor


(Homo sapiens (Human))
BDBM50127607
PNG
((1R,2R)-2-(1H-Imidazol-4-yl)-cyclopropylamine | (1...)
Show SMILES N[C@@H]1C[C@H]1c1cnc[nH]1
Show InChI InChI=1S/C6H9N3/c7-5-1-4(5)6-2-8-3-9-6/h2-5H,1,7H2,(H,8,9)/t4-,5-/m1/s1
PDB

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68n/an/an/an/an/an/an/an/a



Vrije Universiteit

Curated by ChEMBL


Assay Description
Inhibitory activity measured by [3H]- N alpha- methyl-histamine binding to membranes of SK-N-MC cells expressing the human Histamine H3 receptor


J Med Chem 46: 5445-57 (2003)


Article DOI: 10.1021/jm030905y
BindingDB Entry DOI: 10.7270/Q2FN18X0
More data for this
Ligand-Target Pair
Histamine H3 receptor


(Homo sapiens (Human))
BDBM181143
PNG
(US9138393, Immepip dihydrobromide | US9144538, Imm...)
Show SMILES C(C1CCCNC1)c1c[nH]cn1
PDB

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68n/an/an/an/an/an/an/an/a



Vrije Universiteit

Curated by ChEMBL


Assay Description
Inhibitory activity measured by [3H]- N alpha- methyl-histamine binding to membranes of SK-N-MC cells expressing the human Histamine H3 receptor


J Med Chem 46: 5445-57 (2003)


Article DOI: 10.1021/jm030905y
BindingDB Entry DOI: 10.7270/Q2FN18X0
More data for this
Ligand-Target Pair
Histamine H3 receptor


(Homo sapiens (Human))
BDBM50150943
PNG
(CHEMBL154529)
Show SMILES C(CC1CCCNC1)Cc1c[nH]cn1
Show InChI InChI=1S/C11H19N3/c1(5-11-8-13-9-14-11)3-10-4-2-6-12-7-10/h8-10,12H,1-7H2,(H,13,14)
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83n/an/an/an/an/an/an/an/a



Vrije Universiteit

Curated by ChEMBL


Assay Description
Inhibitory activity measured by [3H]- N alpha- methyl-histamine binding to membranes of SK-N-MC cells expressing the human Histamine H3 receptor


J Med Chem 46: 5445-57 (2003)


Article DOI: 10.1021/jm030905y
BindingDB Entry DOI: 10.7270/Q2FN18X0
More data for this
Ligand-Target Pair
Histamine H3 receptor


(Homo sapiens (Human))
BDBM50474430
PNG
(CHEMBL152948)
Show SMILES C(CC1CCCCN1)Cc1c[nH]cn1
Show InChI InChI=1S/C11H19N3/c1-2-7-13-10(4-1)5-3-6-11-8-12-9-14-11/h8-10,13H,1-7H2,(H,12,14)
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93n/an/an/an/an/an/an/an/a



Vrije Universiteit

Curated by ChEMBL


Assay Description
Inhibitory activity measured by [3H]- N alpha- methyl-histamine binding to membranes of SK-N-MC cells expressing the human Histamine H3 receptor


J Med Chem 46: 5445-57 (2003)


Article DOI: 10.1021/jm030905y
BindingDB Entry DOI: 10.7270/Q2FN18X0
More data for this
Ligand-Target Pair
Histamine H4 receptor


(Homo sapiens (Human))
BDBM50474423
PNG
(CHEMBL153284)
Show SMILES NCC1CC1c1c[nH]cn1
Show InChI InChI=1S/C7H11N3/c8-2-5-1-6(5)7-3-9-4-10-7/h3-6H,1-2,8H2,(H,9,10)
PDB

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112n/an/an/an/an/an/an/an/a



Vrije Universiteit

Curated by ChEMBL


Assay Description
Inhibitory activity measured by [3H]- N alpha- methyl-histamine binding to membranes of SK-N-MC cells expressing the human Histamine H4 receptor


J Med Chem 46: 5445-57 (2003)


Article DOI: 10.1021/jm030905y
BindingDB Entry DOI: 10.7270/Q2FN18X0
More data for this
Ligand-Target Pair
Histamine H4 receptor


(Homo sapiens (Human))
BDBM50474424
PNG
(CHEMBL153051)
Show SMILES [H][C@@]1(Cc2c[nH]cn2)CCNC1
Show InChI InChI=1S/C8H13N3/c1-2-9-4-7(1)3-8-5-10-6-11-8/h5-7,9H,1-4H2,(H,10,11)/t7-/m0/s1
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141n/an/an/an/an/an/an/an/a



Vrije Universiteit

Curated by ChEMBL


Assay Description
Inhibitory activity measured by [3H]- N alpha- methyl-histamine binding to membranes of SK-N-MC cells expressing the human Histamine H4 receptor


J Med Chem 46: 5445-57 (2003)


Article DOI: 10.1021/jm030905y
BindingDB Entry DOI: 10.7270/Q2FN18X0
More data for this
Ligand-Target Pair
Histamine H3 receptor


(Homo sapiens (Human))
BDBM50150944
PNG
(CHEMBL153207)
Show SMILES C(Cc1c[nH]cn1)C1CCCNC1
Show InChI InChI=1S/C10H17N3/c1-2-9(6-11-5-1)3-4-10-7-12-8-13-10/h7-9,11H,1-6H2,(H,12,13)
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182n/an/an/an/an/an/an/an/a



Vrije Universiteit

Curated by ChEMBL


Assay Description
Inhibitory activity measured by [3H]- N alpha- methyl-histamine binding to membranes of SK-N-MC cells expressing the human Histamine H3 receptor


J Med Chem 46: 5445-57 (2003)


Article DOI: 10.1021/jm030905y
BindingDB Entry DOI: 10.7270/Q2FN18X0
More data for this
Ligand-Target Pair
Histamine H4 receptor


(Homo sapiens (Human))
BDBM50215536
PNG
((R)-Alpha-Methylhistamine | CHEBI:73337 | CHEMBL26...)
Show SMILES C[C@@H](N)Cc1c[nH]cn1 |r|
Show InChI InChI=1S/C6H11N3/c1-5(7)2-6-3-8-4-9-6/h3-5H,2,7H2,1H3,(H,8,9)/t5-/m1/s1
PDB

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239n/an/an/an/an/an/an/an/a



Vrije Universiteit

Curated by ChEMBL


Assay Description
Inhibitory activity measured by [3H]- N alpha- methyl-histamine binding to membranes of SK-N-MC cells expressing the human Histamine H4 receptor


J Med Chem 46: 5445-57 (2003)


Article DOI: 10.1021/jm030905y
BindingDB Entry DOI: 10.7270/Q2FN18X0
More data for this
Ligand-Target Pair
Histamine H4 receptor


(Homo sapiens (Human))
BDBM50150944
PNG
(CHEMBL153207)
Show SMILES C(Cc1c[nH]cn1)C1CCCNC1
Show InChI InChI=1S/C10H17N3/c1-2-9(6-11-5-1)3-4-10-7-12-8-13-10/h7-9,11H,1-6H2,(H,12,13)
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323n/an/an/an/an/an/an/an/a



Vrije Universiteit

Curated by ChEMBL


Assay Description
Inhibitory activity measured by [3H]- N alpha- methyl-histamine binding to membranes of SK-N-MC cells expressing the human Histamine H4 receptor


J Med Chem 46: 5445-57 (2003)


Article DOI: 10.1021/jm030905y
BindingDB Entry DOI: 10.7270/Q2FN18X0
More data for this
Ligand-Target Pair
Histamine H4 receptor


(Homo sapiens (Human))
BDBM50409216
PNG
(CHEMBL150701)
Show SMILES C(Cc1cnc[nH]1)C1CCNCC1
Show InChI InChI=1S/C10H17N3/c1(2-10-7-12-8-13-10)9-3-5-11-6-4-9/h7-9,11H,1-6H2,(H,12,13)
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371n/an/an/an/an/an/an/an/a



Vrije Universiteit

Curated by ChEMBL


Assay Description
Inhibitory activity measured by [3H]- N alpha- methyl-histamine binding to membranes of SK-N-MC cells expressing the human Histamine H4 receptor


J Med Chem 46: 5445-57 (2003)


Article DOI: 10.1021/jm030905y
BindingDB Entry DOI: 10.7270/Q2FN18X0
More data for this
Ligand-Target Pair
Histamine H4 receptor


(Homo sapiens (Human))
BDBM50474426
PNG
(Impentamine)
Show SMILES NCCCCCc1c[nH]cn1
Show InChI InChI=1S/C8H15N3/c9-5-3-1-2-4-8-6-10-7-11-8/h6-7H,1-5,9H2,(H,10,11)
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371n/an/an/an/an/an/an/an/a



Vrije Universiteit

Curated by ChEMBL


Assay Description
Inhibitory activity measured by [3H]- N alpha- methyl-histamine binding to membranes of SK-N-MC cells expressing the human Histamine H4 receptor


J Med Chem 46: 5445-57 (2003)


Article DOI: 10.1021/jm030905y
BindingDB Entry DOI: 10.7270/Q2FN18X0
More data for this
Ligand-Target Pair
Histamine H4 receptor


(Homo sapiens (Human))
BDBM50150943
PNG
(CHEMBL154529)
Show SMILES C(CC1CCCNC1)Cc1c[nH]cn1
Show InChI InChI=1S/C11H19N3/c1(5-11-8-13-9-14-11)3-10-4-2-6-12-7-10/h8-10,12H,1-7H2,(H,13,14)
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389n/an/an/an/an/an/an/an/a



Vrije Universiteit

Curated by ChEMBL


Assay Description
Inhibitory activity measured by [3H]- N alpha- methyl-histamine binding to membranes of SK-N-MC cells expressing the human Histamine H4 receptor


J Med Chem 46: 5445-57 (2003)


Article DOI: 10.1021/jm030905y
BindingDB Entry DOI: 10.7270/Q2FN18X0
More data for this
Ligand-Target Pair
Histamine H4 receptor


(Homo sapiens (Human))
BDBM50474430
PNG
(CHEMBL152948)
Show SMILES C(CC1CCCCN1)Cc1c[nH]cn1
Show InChI InChI=1S/C11H19N3/c1-2-7-13-10(4-1)5-3-6-11-8-12-9-14-11/h8-10,13H,1-7H2,(H,12,14)
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575n/an/an/an/an/an/an/an/a



Vrije Universiteit

Curated by ChEMBL


Assay Description
Inhibitory activity measured by [3H]- N alpha- methyl-histamine binding to membranes of SK-N-MC cells expressing the human Histamine H4 receptor


J Med Chem 46: 5445-57 (2003)


Article DOI: 10.1021/jm030905y
BindingDB Entry DOI: 10.7270/Q2FN18X0
More data for this
Ligand-Target Pair
Histamine H4 receptor


(Homo sapiens (Human))
BDBM50409817
PNG
(CHEMBL78498 | VUF-5681)
Show SMILES C(CC1CCNCC1)Cc1cnc[nH]1
Show InChI InChI=1S/C11H19N3/c1(3-11-8-13-9-14-11)2-10-4-6-12-7-5-10/h8-10,12H,1-7H2,(H,13,14)
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616n/an/an/an/an/an/an/an/a



Vrije Universiteit

Curated by ChEMBL


Assay Description
Inhibitory activity measured by [3H]- N alpha- methyl-histamine binding to membranes of SK-N-MC cells expressing the human Histamine H4 receptor


J Med Chem 46: 5445-57 (2003)


Article DOI: 10.1021/jm030905y
BindingDB Entry DOI: 10.7270/Q2FN18X0
More data for this
Ligand-Target Pair
Histamine H4 receptor


(Homo sapiens (Human))
BDBM181143
PNG
(US9138393, Immepip dihydrobromide | US9144538, Imm...)
Show SMILES C(C1CCCNC1)c1c[nH]cn1
PDB

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616n/an/an/an/an/an/an/an/a



Vrije Universiteit

Curated by ChEMBL


Assay Description
Inhibitory activity measured by [3H]- N alpha- methyl-histamine binding to membranes of SK-N-MC cells expressing the human Histamine H4 receptor


J Med Chem 46: 5445-57 (2003)


Article DOI: 10.1021/jm030905y
BindingDB Entry DOI: 10.7270/Q2FN18X0
More data for this
Ligand-Target Pair
Histamine H4 receptor


(Homo sapiens (Human))
BDBM50407522
PNG
(CHEMBL554031)
Show SMILES NCCCCCCc1cnc[nH]1
Show InChI InChI=1S/C9H17N3/c10-6-4-2-1-3-5-9-7-11-8-12-9/h7-8H,1-6,10H2,(H,11,12)
PDB

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758n/an/an/an/an/an/an/an/a



Vrije Universiteit

Curated by ChEMBL


Assay Description
Inhibitory activity measured by [3H]- N alpha- methyl-histamine binding to membranes of SK-N-MC cells expressing the human Histamine H4 receptor


J Med Chem 46: 5445-57 (2003)


Article DOI: 10.1021/jm030905y
BindingDB Entry DOI: 10.7270/Q2FN18X0
More data for this
Ligand-Target Pair
Histamine H3 receptor


(Homo sapiens (Human))
BDBM50474422
PNG
(CHEMBL358028)
Show SMILES C1CC(CCN1)c1c[nH]cn1
Show InChI InChI=1S/C8H13N3/c1-3-9-4-2-7(1)8-5-10-6-11-8/h5-7,9H,1-4H2,(H,10,11)
PDB

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871n/an/an/an/an/an/an/an/a



Vrije Universiteit

Curated by ChEMBL


Assay Description
Inhibitory activity measured by [3H]- N alpha- methyl-histamine binding to membranes of SK-N-MC cells expressing the human Histamine H3 receptor


J Med Chem 46: 5445-57 (2003)


Article DOI: 10.1021/jm030905y
BindingDB Entry DOI: 10.7270/Q2FN18X0
More data for this
Ligand-Target Pair
Histamine H4 receptor


(Homo sapiens (Human))
BDBM50127605
PNG
((1S,2S)-2-(1H-Imidazol-4-yl)-cyclopropylamine | (1...)
Show SMILES N[C@H]1C[C@@H]1c1cnc[nH]1
Show InChI InChI=1S/C6H9N3/c7-5-1-4(5)6-2-8-3-9-6/h2-5H,1,7H2,(H,8,9)/t4-,5-/m0/s1
PDB

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1.09E+3n/an/an/an/an/an/an/an/a



Vrije Universiteit

Curated by ChEMBL


Assay Description
Inhibitory activity measured by [3H]- N alpha- methyl-histamine binding to membranes of SK-N-MC cells expressing the human Histamine H4 receptor


J Med Chem 46: 5445-57 (2003)


Article DOI: 10.1021/jm030905y
BindingDB Entry DOI: 10.7270/Q2FN18X0
More data for this
Ligand-Target Pair
Histamine H3 receptor


(Homo sapiens (Human))
BDBM50474434
PNG
(CHEMBL150703)
Show SMILES C(C1CCCCN1)c1c[nH]cn1
Show InChI InChI=1S/C9H15N3/c1-2-4-11-8(3-1)5-9-6-10-7-12-9/h6-8,11H,1-5H2,(H,10,12)
PDB

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1.15E+3n/an/an/an/an/an/an/an/a



Vrije Universiteit

Curated by ChEMBL


Assay Description
Inhibitory activity measured by [3H]- N alpha- methyl-histamine binding to membranes of SK-N-MC cells expressing the human Histamine H3 receptor


J Med Chem 46: 5445-57 (2003)


Article DOI: 10.1021/jm030905y
BindingDB Entry DOI: 10.7270/Q2FN18X0
More data for this
Ligand-Target Pair
Histamine H4 receptor


(Homo sapiens (Human))
BDBM50474425
PNG
(CHEMBL356666)
Show SMILES C1CC(CCN1)=Cc1c[nH]cn1 |(1.48,1.21,;-.04,1.44,;-.6,2.89,;.37,4.08,;1.9,3.85,;2.46,2.41,;-2.12,3.13,;-3.09,1.91,;-4.62,1.98,;-5.16,.53,;-3.97,-.4,;-2.68,.46,)|
Show InChI InChI=1S/C9H13N3/c1-3-10-4-2-8(1)5-9-6-11-7-12-9/h5-7,10H,1-4H2,(H,11,12)
PDB

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1.73E+3n/an/an/an/an/an/an/an/a



Vrije Universiteit

Curated by ChEMBL


Assay Description
Inhibitory activity measured by [3H]- N alpha- methyl-histamine binding to membranes of SK-N-MC cells expressing the human Histamine H4 receptor


J Med Chem 46: 5445-57 (2003)


Article DOI: 10.1021/jm030905y
BindingDB Entry DOI: 10.7270/Q2FN18X0
More data for this
Ligand-Target Pair
Histamine H4 receptor


(Homo sapiens (Human))
BDBM50474422
PNG
(CHEMBL358028)
Show SMILES C1CC(CCN1)c1c[nH]cn1
Show InChI InChI=1S/C8H13N3/c1-3-9-4-2-7(1)8-5-10-6-11-8/h5-7,9H,1-4H2,(H,10,11)
PDB

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2.18E+3n/an/an/an/an/an/an/an/a



Vrije Universiteit

Curated by ChEMBL


Assay Description
Inhibitory activity measured by [3H]- N alpha- methyl-histamine binding to membranes of SK-N-MC cells expressing the human Histamine H4 receptor


J Med Chem 46: 5445-57 (2003)


Article DOI: 10.1021/jm030905y
BindingDB Entry DOI: 10.7270/Q2FN18X0
More data for this
Ligand-Target Pair
Histamine H4 receptor


(Homo sapiens (Human))
BDBM50474428
PNG
(CHEMBL152936)
Show SMILES C=C(C1CCNCC1)c1c[nH]cn1
Show InChI InChI=1S/C10H15N3/c1-8(10-6-12-7-13-10)9-2-4-11-5-3-9/h6-7,9,11H,1-5H2,(H,12,13)
PDB

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2.81E+3n/an/an/an/an/an/an/an/a



Vrije Universiteit

Curated by ChEMBL


Assay Description
Inhibitory activity measured by [3H]- N alpha- methyl-histamine binding to membranes of SK-N-MC cells expressing the human Histamine H4 receptor


J Med Chem 46: 5445-57 (2003)


Article DOI: 10.1021/jm030905y
BindingDB Entry DOI: 10.7270/Q2FN18X0
More data for this
Ligand-Target Pair
Histamine H3 receptor


(Homo sapiens (Human))
BDBM50474431
PNG
(CHEMBL150512)
Show SMILES C(Cc1c[nH]cn1)C1CCCCN1
Show InChI InChI=1S/C10H17N3/c1-2-6-12-9(3-1)4-5-10-7-11-8-13-10/h7-9,12H,1-6H2,(H,11,13)
PDB

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2.82E+3n/an/an/an/an/an/an/an/a



Vrije Universiteit

Curated by ChEMBL


Assay Description
Inhibitory activity measured by [3H]- N alpha- methyl-histamine binding to membranes of SK-N-MC cells expressing the human Histamine H3 receptor


J Med Chem 46: 5445-57 (2003)


Article DOI: 10.1021/jm030905y
BindingDB Entry DOI: 10.7270/Q2FN18X0
More data for this
Ligand-Target Pair
Histamine H4 receptor


(Homo sapiens (Human))
BDBM50127607
PNG
((1R,2R)-2-(1H-Imidazol-4-yl)-cyclopropylamine | (1...)
Show SMILES N[C@@H]1C[C@H]1c1cnc[nH]1
Show InChI InChI=1S/C6H9N3/c7-5-1-4(5)6-2-8-3-9-6/h2-5H,1,7H2,(H,8,9)/t4-,5-/m1/s1
PDB

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3.80E+3n/an/an/an/an/an/an/an/a



Vrije Universiteit

Curated by ChEMBL


Assay Description
Inhibitory activity measured by [3H]- N alpha- methyl-histamine binding to membranes of SK-N-MC cells expressing the human Histamine H4 receptor


J Med Chem 46: 5445-57 (2003)


Article DOI: 10.1021/jm030905y
BindingDB Entry DOI: 10.7270/Q2FN18X0
More data for this
Ligand-Target Pair
Histamine H3 receptor


(Homo sapiens (Human))
BDBM50474432
PNG
(CHEMBL345954)
Show SMILES O=C(C1CCNCC1)c1c[nH]cn1
Show InChI InChI=1S/C9H13N3O/c13-9(8-5-11-6-12-8)7-1-3-10-4-2-7/h5-7,10H,1-4H2,(H,11,12)
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3.89E+3n/an/an/an/an/an/an/an/a



Vrije Universiteit

Curated by ChEMBL


Assay Description
Inhibitory activity measured by [3H]- N alpha- methyl-histamine binding to membranes of SK-N-MC cells expressing the human Histamine H3 receptor


J Med Chem 46: 5445-57 (2003)


Article DOI: 10.1021/jm030905y
BindingDB Entry DOI: 10.7270/Q2FN18X0
More data for this
Ligand-Target Pair
Histamine H3 receptor


(Homo sapiens (Human))
BDBM50474429
PNG
(CHEMBL150243)
Show SMILES C1CC(=CCN1)c1c[nH]cn1 |c:2|
Show InChI InChI=1S/C8H11N3/c1-3-9-4-2-7(1)8-5-10-6-11-8/h1,5-6,9H,2-4H2,(H,10,11)
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UniChem
Article
PubMed
4.27E+3n/an/an/an/an/an/an/an/a



Vrije Universiteit

Curated by ChEMBL


Assay Description
Inhibitory activity measured by [3H]- N alpha- methyl-histamine binding to membranes of SK-N-MC cells expressing the human Histamine H3 receptor


J Med Chem 46: 5445-57 (2003)


Article DOI: 10.1021/jm030905y
BindingDB Entry DOI: 10.7270/Q2FN18X0
More data for this
Ligand-Target Pair
Histamine H4 receptor


(Homo sapiens (Human))
BDBM50474431
PNG
(CHEMBL150512)
Show SMILES C(Cc1c[nH]cn1)C1CCCCN1
Show InChI InChI=1S/C10H17N3/c1-2-6-12-9(3-1)4-5-10-7-11-8-13-10/h7-9,12H,1-6H2,(H,11,13)
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4.46E+3n/an/an/an/an/an/an/an/a



Vrije Universiteit

Curated by ChEMBL


Assay Description
Inhibitory activity measured by [3H]- N alpha- methyl-histamine binding to membranes of SK-N-MC cells expressing the human Histamine H4 receptor


J Med Chem 46: 5445-57 (2003)


Article DOI: 10.1021/jm030905y
BindingDB Entry DOI: 10.7270/Q2FN18X0
More data for this
Ligand-Target Pair
Histamine H4 receptor


(Homo sapiens (Human))
BDBM50474434
PNG
(CHEMBL150703)
Show SMILES C(C1CCCCN1)c1c[nH]cn1
Show InChI InChI=1S/C9H15N3/c1-2-4-11-8(3-1)5-9-6-10-7-12-9/h6-8,11H,1-5H2,(H,10,12)
PDB

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UniChem
Article
PubMed
8.91E+3n/an/an/an/an/an/an/an/a



Vrije Universiteit

Curated by ChEMBL


Assay Description
Inhibitory activity measured by [3H]- N alpha- methyl-histamine binding to membranes of SK-N-MC cells expressing the human Histamine H4 receptor


J Med Chem 46: 5445-57 (2003)


Article DOI: 10.1021/jm030905y
BindingDB Entry DOI: 10.7270/Q2FN18X0
More data for this
Ligand-Target Pair
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