Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Prostaglandin E synthase (Homo sapiens (Human)) | BDBM50227631 (2-(6-chloro-1H-phenanthro[9,10-d]imidazol-2-yl)iso...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid PDB UniChem Similars | PDB Article PubMed | n/a | n/a | 1.90 | n/a | n/a | n/a | n/a | n/a | n/a |
Glenmark Pharmaceuticals Limited Curated by ChEMBL | Assay Description Inhibition of recombinant human mPGES-1 expressed in CHO cells assessed as reduction in PGE2 formation using PGH2 a substrate preincubated for 10 min... | Bioorg Med Chem Lett 27: 2594-2601 (2017) Article DOI: 10.1016/j.bmcl.2017.03.068 BindingDB Entry DOI: 10.7270/Q24B33Q3 | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Prostaglandin E synthase (Homo sapiens (Human)) | BDBM50227631 (2-(6-chloro-1H-phenanthro[9,10-d]imidazol-2-yl)iso...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid PDB UniChem Similars | PDB Article PubMed | n/a | n/a | 1.90 | n/a | n/a | n/a | n/a | n/a | n/a |
Glenmark Pharmaceuticals Limited Curated by ChEMBL | Assay Description Inhibition of human recombinant mPGES-1 expressed in CHO cells assessed as reduction in conversion of PGH2 to PGE2 incubated for 10 mins followed by ... | Bioorg Med Chem Lett 26: 5977-5984 (2016) Article DOI: 10.1016/j.bmcl.2016.10.079 BindingDB Entry DOI: 10.7270/Q2XK8HJ8 | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Prostaglandin E synthase (Homo sapiens (Human)) | BDBM50452066 (CHEMBL4206145) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 2.20 | n/a | n/a | n/a | n/a | n/a | n/a |
Glenmark Pharmaceuticals Limited Curated by ChEMBL | Assay Description Inhibition of recombinant human mPGES1 expressed in CHO cells using PGH2 as substrate pretreated for 10 mins followed by substrate addition measured ... | Bioorg Med Chem Lett 27: 5131-5138 (2017) Article DOI: 10.1016/j.bmcl.2017.10.062 BindingDB Entry DOI: 10.7270/Q2JS9T0V | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin E synthase (Homo sapiens (Human)) | BDBM50452084 (CHEMBL4207228) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 2.30 | n/a | n/a | n/a | n/a | n/a | n/a |
Glenmark Pharmaceuticals Limited Curated by ChEMBL | Assay Description Inhibition of recombinant human mPGES1 expressed in CHO cells using PGH2 as substrate pretreated for 10 mins followed by substrate addition measured ... | Bioorg Med Chem Lett 27: 5131-5138 (2017) Article DOI: 10.1016/j.bmcl.2017.10.062 BindingDB Entry DOI: 10.7270/Q2JS9T0V | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin E synthase (Homo sapiens (Human)) | BDBM50207335 (CHEMBL3961834) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | 2.60 | n/a | n/a | n/a | n/a | n/a | n/a |
Glenmark Pharmaceuticals Limited Curated by ChEMBL | Assay Description Inhibition of mPGES1 in human A549 cells assessed as reduction in IL-1beta-induced PGE2 production preincubated for 30 mins followed by incubation wi... | Bioorg Med Chem Lett 28: 1211-1218 (2018) Article DOI: 10.1016/j.bmcl.2018.02.048 BindingDB Entry DOI: 10.7270/Q2N300K5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin E synthase (Homo sapiens (Human)) | BDBM50452071 (CHEMBL4208718) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 2.80 | n/a | n/a | n/a | n/a | n/a | n/a |
Glenmark Pharmaceuticals Limited Curated by ChEMBL | Assay Description Inhibition of recombinant human mPGES1 expressed in CHO cells using PGH2 as substrate pretreated for 10 mins followed by substrate addition measured ... | Bioorg Med Chem Lett 27: 5131-5138 (2017) Article DOI: 10.1016/j.bmcl.2017.10.062 BindingDB Entry DOI: 10.7270/Q2JS9T0V | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin E synthase (Homo sapiens (Human)) | BDBM50460529 (CHEMBL4228804) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 3 | n/a | n/a | n/a | n/a | n/a | n/a |
Glenmark Pharmaceuticals Limited Curated by ChEMBL | Assay Description Inhibition of recombinant human mPGES1 expressed in CHO cells assessed as reduction in PGE2 production using PGH2 as substrate incubated for 10 mins ... | Bioorg Med Chem Lett 28: 1211-1218 (2018) Article DOI: 10.1016/j.bmcl.2018.02.048 BindingDB Entry DOI: 10.7270/Q2N300K5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin E synthase (Homo sapiens (Human)) | BDBM50460527 (CHEMBL4228430) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 3 | n/a | n/a | n/a | n/a | n/a | n/a |
Glenmark Pharmaceuticals Limited Curated by ChEMBL | Assay Description Inhibition of mPGES1 in human A549 cells assessed as reduction in IL-1beta-induced PGE2 production preincubated for 30 mins followed by incubation wi... | Bioorg Med Chem Lett 28: 1211-1218 (2018) Article DOI: 10.1016/j.bmcl.2018.02.048 BindingDB Entry DOI: 10.7270/Q2N300K5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin E synthase (Homo sapiens (Human)) | BDBM124296 (US8759537, 33) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 3 | n/a | n/a | n/a | n/a | n/a | n/a |
Glenmark Pharmaceuticals Limited Curated by ChEMBL | Assay Description Inhibition of recombinant human mPGES1 using PGH2 as substrate pretreated for 25 mins followed by substrate addition measured after 60 secs by HTRF a... | Bioorg Med Chem Lett 27: 5131-5138 (2017) Article DOI: 10.1016/j.bmcl.2017.10.062 BindingDB Entry DOI: 10.7270/Q2JS9T0V | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin E synthase (Homo sapiens (Human)) | BDBM50460540 (CHEMBL4227388) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 3.10 | n/a | n/a | n/a | n/a | n/a | n/a |
Glenmark Pharmaceuticals Limited Curated by ChEMBL | Assay Description Inhibition of recombinant human mPGES1 expressed in CHO cells assessed as reduction in PGE2 production using PGH2 as substrate incubated for 10 mins ... | Bioorg Med Chem Lett 28: 1211-1218 (2018) Article DOI: 10.1016/j.bmcl.2018.02.048 BindingDB Entry DOI: 10.7270/Q2N300K5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin E synthase (Homo sapiens (Human)) | BDBM50460542 (CHEMBL4227545) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 3.10 | n/a | n/a | n/a | n/a | n/a | n/a |
Glenmark Pharmaceuticals Limited Curated by ChEMBL | Assay Description Inhibition of recombinant human mPGES1 expressed in CHO cells assessed as reduction in PGE2 production using PGH2 as substrate incubated for 10 mins ... | Bioorg Med Chem Lett 28: 1211-1218 (2018) Article DOI: 10.1016/j.bmcl.2018.02.048 BindingDB Entry DOI: 10.7270/Q2N300K5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin E synthase (Homo sapiens (Human)) | BDBM50207335 (CHEMBL3961834) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | 3.20 | n/a | n/a | n/a | n/a | n/a | n/a |
Glenmark Pharmaceuticals Limited Curated by ChEMBL | Assay Description Inhibition of human recombinant mPGES-1 expressed in CHO cells assessed as reduction in conversion of PGH2 to PGE2 incubated for 10 mins followed by ... | Bioorg Med Chem Lett 26: 5977-5984 (2016) Article DOI: 10.1016/j.bmcl.2016.10.079 BindingDB Entry DOI: 10.7270/Q2XK8HJ8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin E synthase (Homo sapiens (Human)) | BDBM50460537 (CHEMBL4226536) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 3.20 | n/a | n/a | n/a | n/a | n/a | n/a |
Glenmark Pharmaceuticals Limited Curated by ChEMBL | Assay Description Inhibition of recombinant human mPGES1 expressed in CHO cells assessed as reduction in PGE2 production using PGH2 as substrate incubated for 10 mins ... | Bioorg Med Chem Lett 28: 1211-1218 (2018) Article DOI: 10.1016/j.bmcl.2018.02.048 BindingDB Entry DOI: 10.7270/Q2N300K5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin E synthase (Homo sapiens (Human)) | BDBM50207335 (CHEMBL3961834) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | 3.30 | n/a | n/a | n/a | n/a | n/a | n/a |
Glenmark Pharmaceuticals Limited Curated by ChEMBL | Assay Description Inhibition of recombinant human mPGES1 expressed in CHO cells assessed as reduction in PGE2 production using PGH2 as substrate incubated for 10 mins ... | Bioorg Med Chem Lett 28: 1211-1218 (2018) Article DOI: 10.1016/j.bmcl.2018.02.048 BindingDB Entry DOI: 10.7270/Q2N300K5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin E synthase (Homo sapiens (Human)) | BDBM50460531 (CHEMBL4226545) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 3.30 | n/a | n/a | n/a | n/a | n/a | n/a |
Glenmark Pharmaceuticals Limited Curated by ChEMBL | Assay Description Inhibition of recombinant human mPGES1 expressed in CHO cells assessed as reduction in PGE2 production using PGH2 as substrate incubated for 10 mins ... | Bioorg Med Chem Lett 28: 1211-1218 (2018) Article DOI: 10.1016/j.bmcl.2018.02.048 BindingDB Entry DOI: 10.7270/Q2N300K5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin E synthase (Homo sapiens (Human)) | BDBM50452078 (CHEMBL4203842) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 3.5 | n/a | n/a | n/a | n/a | n/a | n/a |
Glenmark Pharmaceuticals Limited Curated by ChEMBL | Assay Description Inhibition of recombinant human mPGES1 expressed in CHO cells using PGH2 as substrate pretreated for 10 mins followed by substrate addition measured ... | Bioorg Med Chem Lett 27: 5131-5138 (2017) Article DOI: 10.1016/j.bmcl.2017.10.062 BindingDB Entry DOI: 10.7270/Q2JS9T0V | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin E synthase (Homo sapiens (Human)) | BDBM50207322 (CHEMBL3916119) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 3.60 | n/a | n/a | n/a | n/a | n/a | n/a |
Glenmark Pharmaceuticals Limited Curated by ChEMBL | Assay Description Inhibition of human recombinant mPGES-1 expressed in CHO cells assessed as reduction in conversion of PGH2 to PGE2 incubated for 10 mins followed by ... | Bioorg Med Chem Lett 26: 5977-5984 (2016) Article DOI: 10.1016/j.bmcl.2016.10.079 BindingDB Entry DOI: 10.7270/Q2XK8HJ8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin E synthase (Homo sapiens (Human)) | BDBM50460536 (CHEMBL4225183) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 3.60 | n/a | n/a | n/a | n/a | n/a | n/a |
Glenmark Pharmaceuticals Limited Curated by ChEMBL | Assay Description Inhibition of recombinant human mPGES1 expressed in CHO cells assessed as reduction in PGE2 production using PGH2 as substrate incubated for 10 mins ... | Bioorg Med Chem Lett 28: 1211-1218 (2018) Article DOI: 10.1016/j.bmcl.2018.02.048 BindingDB Entry DOI: 10.7270/Q2N300K5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin E synthase (Homo sapiens (Human)) | BDBM50452073 (CHEMBL4210425) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 3.70 | n/a | n/a | n/a | n/a | n/a | n/a |
Glenmark Pharmaceuticals Limited Curated by ChEMBL | Assay Description Inhibition of recombinant human mPGES1 expressed in CHO cells using PGH2 as substrate pretreated for 10 mins followed by substrate addition measured ... | Bioorg Med Chem Lett 27: 5131-5138 (2017) Article DOI: 10.1016/j.bmcl.2017.10.062 BindingDB Entry DOI: 10.7270/Q2JS9T0V | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin E synthase (Homo sapiens (Human)) | BDBM50452079 (CHEMBL4206581) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 3.70 | n/a | n/a | n/a | n/a | n/a | n/a |
Glenmark Pharmaceuticals Limited Curated by ChEMBL | Assay Description Inhibition of recombinant human mPGES1 expressed in CHO cells using PGH2 as substrate pretreated for 10 mins followed by substrate addition measured ... | Bioorg Med Chem Lett 27: 5131-5138 (2017) Article DOI: 10.1016/j.bmcl.2017.10.062 BindingDB Entry DOI: 10.7270/Q2JS9T0V | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin E synthase (Homo sapiens (Human)) | BDBM50207343 (CHEMBL3931344) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 3.90 | n/a | n/a | n/a | n/a | n/a | n/a |
Glenmark Pharmaceuticals Limited Curated by ChEMBL | Assay Description Inhibition of human recombinant mPGES-1 expressed in CHO cells assessed as reduction in conversion of PGH2 to PGE2 incubated for 10 mins followed by ... | Bioorg Med Chem Lett 26: 5977-5984 (2016) Article DOI: 10.1016/j.bmcl.2016.10.079 BindingDB Entry DOI: 10.7270/Q2XK8HJ8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin E synthase (Homo sapiens (Human)) | BDBM50207343 (CHEMBL3931344) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 3.90 | n/a | n/a | n/a | n/a | n/a | n/a |
Glenmark Pharmaceuticals Limited Curated by ChEMBL | Assay Description Inhibition of recombinant human mPGES1 expressed in CHO cells using PGH2 as substrate pretreated for 10 mins followed by substrate addition measured ... | Bioorg Med Chem Lett 27: 5131-5138 (2017) Article DOI: 10.1016/j.bmcl.2017.10.062 BindingDB Entry DOI: 10.7270/Q2JS9T0V | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin E synthase (Homo sapiens (Human)) | BDBM50248978 (CHEMBL4076884) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 3.90 | n/a | n/a | n/a | n/a | n/a | n/a |
Glenmark Pharmaceuticals Limited Curated by ChEMBL | Assay Description Inhibition of recombinant human mPGES-1 expressed in CHO cells assessed as reduction in PGE2 formation using PGH2 a substrate preincubated for 10 min... | Bioorg Med Chem Lett 27: 2594-2601 (2017) Article DOI: 10.1016/j.bmcl.2017.03.068 BindingDB Entry DOI: 10.7270/Q24B33Q3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin E synthase (Homo sapiens (Human)) | BDBM124296 (US8759537, 33) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 4 | n/a | n/a | n/a | n/a | n/a | n/a |
Glenmark Pharmaceuticals Limited Curated by ChEMBL | Assay Description Inhibition of recombinant human mPGES-1 expressed in Escherichia coli Rosetta microsomes assessed as reduction in conversion of PGH2 to PGE2 incubate... | Bioorg Med Chem Lett 26: 5977-5984 (2016) Article DOI: 10.1016/j.bmcl.2016.10.079 BindingDB Entry DOI: 10.7270/Q2XK8HJ8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin E synthase (Homo sapiens (Human)) | BDBM50460541 (CHEMBL4225710) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 4 | n/a | n/a | n/a | n/a | n/a | n/a |
Glenmark Pharmaceuticals Limited Curated by ChEMBL | Assay Description Inhibition of mPGES1 in human A549 cells assessed as reduction in IL-1beta-induced PGE2 production preincubated for 30 mins followed by incubation wi... | Bioorg Med Chem Lett 28: 1211-1218 (2018) Article DOI: 10.1016/j.bmcl.2018.02.048 BindingDB Entry DOI: 10.7270/Q2N300K5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin E synthase (Homo sapiens (Human)) | BDBM50460534 (CHEMBL4229061) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 4.10 | n/a | n/a | n/a | n/a | n/a | n/a |
Glenmark Pharmaceuticals Limited Curated by ChEMBL | Assay Description Inhibition of mPGES1 in human A549 cells assessed as reduction in IL-1beta-induced PGE2 production preincubated for 30 mins followed by incubation wi... | Bioorg Med Chem Lett 28: 1211-1218 (2018) Article DOI: 10.1016/j.bmcl.2018.02.048 BindingDB Entry DOI: 10.7270/Q2N300K5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin E synthase (Homo sapiens (Human)) | BDBM50452070 (CHEMBL4204420) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 4.10 | n/a | n/a | n/a | n/a | n/a | n/a |
Glenmark Pharmaceuticals Limited Curated by ChEMBL | Assay Description Inhibition of recombinant human mPGES1 expressed in CHO cells using PGH2 as substrate pretreated for 10 mins followed by substrate addition measured ... | Bioorg Med Chem Lett 27: 5131-5138 (2017) Article DOI: 10.1016/j.bmcl.2017.10.062 BindingDB Entry DOI: 10.7270/Q2JS9T0V | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin E synthase (Homo sapiens (Human)) | BDBM50452070 (CHEMBL4204420) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 4.10 | n/a | n/a | n/a | n/a | n/a | n/a |
Glenmark Pharmaceuticals Limited Curated by ChEMBL | Assay Description Inhibition of mPGES1 in human A549 cells assessed as reduction in IL-1beta induced PGE2 production pretreated for 30 mins followed by IL-1beta additi... | Bioorg Med Chem Lett 27: 5131-5138 (2017) Article DOI: 10.1016/j.bmcl.2017.10.062 BindingDB Entry DOI: 10.7270/Q2JS9T0V | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin E synthase (Homo sapiens (Human)) | BDBM50207345 (CHEMBL3944077) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | 4.20 | n/a | n/a | n/a | n/a | n/a | n/a |
Glenmark Pharmaceuticals Limited Curated by ChEMBL | Assay Description Inhibition of human recombinant mPGES-1 expressed in CHO cells assessed as reduction in conversion of PGH2 to PGE2 incubated for 10 mins followed by ... | Bioorg Med Chem Lett 26: 5977-5984 (2016) Article DOI: 10.1016/j.bmcl.2016.10.079 BindingDB Entry DOI: 10.7270/Q2XK8HJ8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin E synthase (Homo sapiens (Human)) | BDBM50452044 (CHEMBL4213901) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 4.20 | n/a | n/a | n/a | n/a | n/a | n/a |
Glenmark Pharmaceuticals Limited Curated by ChEMBL | Assay Description Inhibition of recombinant human mPGES1 expressed in CHO cells using PGH2 as substrate pretreated for 10 mins followed by substrate addition measured ... | Bioorg Med Chem Lett 27: 5131-5138 (2017) Article DOI: 10.1016/j.bmcl.2017.10.062 BindingDB Entry DOI: 10.7270/Q2JS9T0V | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin E synthase (Homo sapiens (Human)) | BDBM50452044 (CHEMBL4213901) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 4.30 | n/a | n/a | n/a | n/a | n/a | n/a |
Glenmark Pharmaceuticals Limited Curated by ChEMBL | Assay Description Inhibition of mPGES1 in human A549 cells assessed as reduction in IL-1beta induced PGE2 production pretreated for 30 mins followed by IL-1beta additi... | Bioorg Med Chem Lett 27: 5131-5138 (2017) Article DOI: 10.1016/j.bmcl.2017.10.062 BindingDB Entry DOI: 10.7270/Q2JS9T0V | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin E synthase (Homo sapiens (Human)) | BDBM50460539 (CHEMBL4225160) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 4.30 | n/a | n/a | n/a | n/a | n/a | n/a |
Glenmark Pharmaceuticals Limited Curated by ChEMBL | Assay Description Inhibition of recombinant human mPGES1 expressed in CHO cells assessed as reduction in PGE2 production using PGH2 as substrate incubated for 10 mins ... | Bioorg Med Chem Lett 28: 1211-1218 (2018) Article DOI: 10.1016/j.bmcl.2018.02.048 BindingDB Entry DOI: 10.7270/Q2N300K5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin E synthase (Homo sapiens (Human)) | BDBM50452079 (CHEMBL4206581) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 4.40 | n/a | n/a | n/a | n/a | n/a | n/a |
Glenmark Pharmaceuticals Limited Curated by ChEMBL | Assay Description Inhibition of mPGES1 in human A549 cells assessed as reduction in IL-1beta induced PGE2 production pretreated for 30 mins followed by IL-1beta additi... | Bioorg Med Chem Lett 27: 5131-5138 (2017) Article DOI: 10.1016/j.bmcl.2017.10.062 BindingDB Entry DOI: 10.7270/Q2JS9T0V | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin E synthase (Homo sapiens (Human)) | BDBM50452045 (CHEMBL4211033) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 4.60 | n/a | n/a | n/a | n/a | n/a | n/a |
Glenmark Pharmaceuticals Limited Curated by ChEMBL | Assay Description Inhibition of recombinant human mPGES1 expressed in CHO cells using PGH2 as substrate pretreated for 10 mins followed by substrate addition measured ... | Bioorg Med Chem Lett 27: 5131-5138 (2017) Article DOI: 10.1016/j.bmcl.2017.10.062 BindingDB Entry DOI: 10.7270/Q2JS9T0V | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin E synthase (Homo sapiens (Human)) | BDBM50452074 (CHEMBL4204099) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 4.70 | n/a | n/a | n/a | n/a | n/a | n/a |
Glenmark Pharmaceuticals Limited Curated by ChEMBL | Assay Description Inhibition of recombinant human mPGES1 expressed in CHO cells using PGH2 as substrate pretreated for 10 mins followed by substrate addition measured ... | Bioorg Med Chem Lett 27: 5131-5138 (2017) Article DOI: 10.1016/j.bmcl.2017.10.062 BindingDB Entry DOI: 10.7270/Q2JS9T0V | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin E synthase (Homo sapiens (Human)) | BDBM50460539 (CHEMBL4225160) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 4.90 | n/a | n/a | n/a | n/a | n/a | n/a |
Glenmark Pharmaceuticals Limited Curated by ChEMBL | Assay Description Inhibition of recombinant human mPGES1 expressed in CHO cells assessed as reduction in PGE2 production using PGH2 as substrate incubated for 10 mins ... | Bioorg Med Chem Lett 28: 1211-1218 (2018) Article DOI: 10.1016/j.bmcl.2018.02.048 BindingDB Entry DOI: 10.7270/Q2N300K5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin E synthase (Homo sapiens (Human)) | BDBM50460533 (CHEMBL4225008) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 4.90 | n/a | n/a | n/a | n/a | n/a | n/a |
Glenmark Pharmaceuticals Limited Curated by ChEMBL | Assay Description Inhibition of recombinant human mPGES1 expressed in CHO cells assessed as reduction in PGE2 production using PGH2 as substrate incubated for 10 mins ... | Bioorg Med Chem Lett 28: 1211-1218 (2018) Article DOI: 10.1016/j.bmcl.2018.02.048 BindingDB Entry DOI: 10.7270/Q2N300K5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin E synthase (Homo sapiens (Human)) | BDBM50460528 (CHEMBL4224969) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 5 | n/a | n/a | n/a | n/a | n/a | n/a |
Glenmark Pharmaceuticals Limited Curated by ChEMBL | Assay Description Inhibition of recombinant human mPGES1 expressed in CHO cells assessed as reduction in PGE2 production using PGH2 as substrate incubated for 10 mins ... | Bioorg Med Chem Lett 28: 1211-1218 (2018) Article DOI: 10.1016/j.bmcl.2018.02.048 BindingDB Entry DOI: 10.7270/Q2N300K5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin E synthase (Homo sapiens (Human)) | BDBM50460526 (CHEMBL4224733) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 5.10 | n/a | n/a | n/a | n/a | n/a | n/a |
Glenmark Pharmaceuticals Limited Curated by ChEMBL | Assay Description Inhibition of recombinant human mPGES1 expressed in CHO cells assessed as reduction in PGE2 production using PGH2 as substrate incubated for 10 mins ... | Bioorg Med Chem Lett 28: 1211-1218 (2018) Article DOI: 10.1016/j.bmcl.2018.02.048 BindingDB Entry DOI: 10.7270/Q2N300K5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin E synthase (Homo sapiens (Human)) | BDBM50460533 (CHEMBL4225008) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 5.20 | n/a | n/a | n/a | n/a | n/a | n/a |
Glenmark Pharmaceuticals Limited Curated by ChEMBL | Assay Description Inhibition of recombinant human mPGES1 expressed in CHO cells assessed as reduction in PGE2 production using PGH2 as substrate incubated for 10 mins ... | Bioorg Med Chem Lett 28: 1211-1218 (2018) Article DOI: 10.1016/j.bmcl.2018.02.048 BindingDB Entry DOI: 10.7270/Q2N300K5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin E synthase (Homo sapiens (Human)) | BDBM50460543 (CHEMBL4226526) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 5.40 | n/a | n/a | n/a | n/a | n/a | n/a |
Glenmark Pharmaceuticals Limited Curated by ChEMBL | Assay Description Inhibition of recombinant human mPGES1 expressed in CHO cells assessed as reduction in PGE2 production using PGH2 as substrate incubated for 10 mins ... | Bioorg Med Chem Lett 28: 1211-1218 (2018) Article DOI: 10.1016/j.bmcl.2018.02.048 BindingDB Entry DOI: 10.7270/Q2N300K5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin E synthase (Homo sapiens (Human)) | BDBM50460527 (CHEMBL4228430) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 5.70 | n/a | n/a | n/a | n/a | n/a | n/a |
Glenmark Pharmaceuticals Limited Curated by ChEMBL | Assay Description Inhibition of recombinant human mPGES1 expressed in CHO cells assessed as reduction in PGE2 production using PGH2 as substrate incubated for 10 mins ... | Bioorg Med Chem Lett 28: 1211-1218 (2018) Article DOI: 10.1016/j.bmcl.2018.02.048 BindingDB Entry DOI: 10.7270/Q2N300K5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin E synthase (Homo sapiens (Human)) | BDBM50452072 (CHEMBL4218836) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 5.80 | n/a | n/a | n/a | n/a | n/a | n/a |
Glenmark Pharmaceuticals Limited Curated by ChEMBL | Assay Description Inhibition of recombinant human mPGES1 expressed in CHO cells using PGH2 as substrate pretreated for 10 mins followed by substrate addition measured ... | Bioorg Med Chem Lett 27: 5131-5138 (2017) Article DOI: 10.1016/j.bmcl.2017.10.062 BindingDB Entry DOI: 10.7270/Q2JS9T0V | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin E synthase (Homo sapiens (Human)) | BDBM50460536 (CHEMBL4225183) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 6 | n/a | n/a | n/a | n/a | n/a | n/a |
Glenmark Pharmaceuticals Limited Curated by ChEMBL | Assay Description Inhibition of mPGES1 in human A549 cells assessed as reduction in IL-1beta-induced PGE2 production preincubated for 30 mins followed by incubation wi... | Bioorg Med Chem Lett 28: 1211-1218 (2018) Article DOI: 10.1016/j.bmcl.2018.02.048 BindingDB Entry DOI: 10.7270/Q2N300K5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin E synthase (Homo sapiens (Human)) | BDBM50460546 (CHEMBL4227610) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 6 | n/a | n/a | n/a | n/a | n/a | n/a |
Glenmark Pharmaceuticals Limited Curated by ChEMBL | Assay Description Inhibition of mPGES1 in human A549 cells assessed as reduction in IL-1beta-induced PGE2 production preincubated for 30 mins followed by incubation wi... | Bioorg Med Chem Lett 28: 1211-1218 (2018) Article DOI: 10.1016/j.bmcl.2018.02.048 BindingDB Entry DOI: 10.7270/Q2N300K5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alcohol dehydrogenase class-3 (Homo sapiens (Human)) | BDBM50465807 (CHEMBL4291042) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 6.10 | n/a | n/a | n/a | n/a | n/a | n/a |
Glenmark Pharmaceuticals Limited Curated by ChEMBL | Assay Description Inhibition of human GSNOR assessed as reduction in NADH consumption after 3 mins by spectrophotometric analysis | Bioorg Med Chem Lett 28: 3766-3773 (2018) Article DOI: 10.1016/j.bmcl.2018.10.012 BindingDB Entry DOI: 10.7270/Q21G0PZK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin E synthase (Homo sapiens (Human)) | BDBM50460546 (CHEMBL4227610) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 6.10 | n/a | n/a | n/a | n/a | n/a | n/a |
Glenmark Pharmaceuticals Limited Curated by ChEMBL | Assay Description Inhibition of recombinant human mPGES1 expressed in CHO cells assessed as reduction in PGE2 production using PGH2 as substrate incubated for 10 mins ... | Bioorg Med Chem Lett 28: 1211-1218 (2018) Article DOI: 10.1016/j.bmcl.2018.02.048 BindingDB Entry DOI: 10.7270/Q2N300K5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin E synthase (Homo sapiens (Human)) | BDBM50452046 (CHEMBL4203493) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 6.20 | n/a | n/a | n/a | n/a | n/a | n/a |
Glenmark Pharmaceuticals Limited Curated by ChEMBL | Assay Description Inhibition of recombinant human mPGES1 expressed in CHO cells using PGH2 as substrate pretreated for 10 mins followed by substrate addition measured ... | Bioorg Med Chem Lett 27: 5131-5138 (2017) Article DOI: 10.1016/j.bmcl.2017.10.062 BindingDB Entry DOI: 10.7270/Q2JS9T0V | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin E synthase (Homo sapiens (Human)) | BDBM50460535 (CHEMBL4226379) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 6.30 | n/a | n/a | n/a | n/a | n/a | n/a |
Glenmark Pharmaceuticals Limited Curated by ChEMBL | Assay Description Inhibition of recombinant human mPGES1 expressed in CHO cells assessed as reduction in PGE2 production using PGH2 as substrate incubated for 10 mins ... | Bioorg Med Chem Lett 28: 1211-1218 (2018) Article DOI: 10.1016/j.bmcl.2018.02.048 BindingDB Entry DOI: 10.7270/Q2N300K5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin E synthase (Homo sapiens (Human)) | BDBM50452069 (CHEMBL4218250) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 6.30 | n/a | n/a | n/a | n/a | n/a | n/a |
Glenmark Pharmaceuticals Limited Curated by ChEMBL | Assay Description Inhibition of recombinant human mPGES1 expressed in CHO cells using PGH2 as substrate pretreated for 10 mins followed by substrate addition measured ... | Bioorg Med Chem Lett 27: 5131-5138 (2017) Article DOI: 10.1016/j.bmcl.2017.10.062 BindingDB Entry DOI: 10.7270/Q2JS9T0V | |||||||||||
More data for this Ligand-Target Pair |
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