Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Sodium-dependent serotonin transporter (Homo sapiens (Human)) | BDBM50432574 (CHEMBL2347169) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 0.900 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ Libre de Bruxelles Curated by ChEMBL | Assay Description Inhibition of serotonin reuptake at human SERT expressed in HEK293 cells coexpressing macrophage scavenger receptor | J Med Chem 56: 3943-58 (2013) Article DOI: 10.1021/jm4001538 BindingDB Entry DOI: 10.7270/Q21C1Z7T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium-dependent serotonin transporter (Homo sapiens (Human)) | BDBM50432575 (CHEMBL2347168) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 2.30 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ Libre de Bruxelles Curated by ChEMBL | Assay Description Inhibition of serotonin reuptake at human SERT expressed in HEK293 cells coexpressing macrophage scavenger receptor | J Med Chem 56: 3943-58 (2013) Article DOI: 10.1021/jm4001538 BindingDB Entry DOI: 10.7270/Q21C1Z7T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium-dependent serotonin transporter (Homo sapiens (Human)) | BDBM50432580 (CHEMBL2347032) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 8 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ Libre de Bruxelles Curated by ChEMBL | Assay Description Inhibition of serotonin reuptake at human SERT expressed in HEK293 cells coexpressing macrophage scavenger receptor | J Med Chem 56: 3943-58 (2013) Article DOI: 10.1021/jm4001538 BindingDB Entry DOI: 10.7270/Q21C1Z7T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium-dependent serotonin transporter (Homo sapiens (Human)) | BDBM50432577 (CHEMBL2347166) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ Libre de Bruxelles Curated by ChEMBL | Assay Description Inhibition of serotonin reuptake at human SERT expressed in HEK293 cells coexpressing macrophage scavenger receptor | J Med Chem 56: 3943-58 (2013) Article DOI: 10.1021/jm4001538 BindingDB Entry DOI: 10.7270/Q21C1Z7T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium-dependent serotonin transporter (Homo sapiens (Human)) | BDBM50432567 (CHEMBL2347178) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 12 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ Libre de Bruxelles Curated by ChEMBL | Assay Description Inhibition of serotonin reuptake at human SERT expressed in HEK293 cells coexpressing macrophage scavenger receptor | J Med Chem 56: 3943-58 (2013) Article DOI: 10.1021/jm4001538 BindingDB Entry DOI: 10.7270/Q21C1Z7T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium-dependent serotonin transporter (Homo sapiens (Human)) | BDBM50432570 (CHEMBL2347175) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | 12 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ Libre de Bruxelles Curated by ChEMBL | Assay Description Inhibition of serotonin reuptake at human SERT expressed in HEK293 cells coexpressing macrophage scavenger receptor | J Med Chem 56: 3943-58 (2013) Article DOI: 10.1021/jm4001538 BindingDB Entry DOI: 10.7270/Q21C1Z7T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium-dependent serotonin transporter (Homo sapiens (Human)) | BDBM50432569 (CHEMBL2347176) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ Libre de Bruxelles Curated by ChEMBL | Assay Description Inhibition of serotonin reuptake at human SERT expressed in HEK293 cells coexpressing macrophage scavenger receptor | J Med Chem 56: 3943-58 (2013) Article DOI: 10.1021/jm4001538 BindingDB Entry DOI: 10.7270/Q21C1Z7T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium-dependent serotonin transporter (Homo sapiens (Human)) | BDBM50432581 (CHEMBL2347030) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 24 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ Libre de Bruxelles Curated by ChEMBL | Assay Description Inhibition of serotonin reuptake at human SERT expressed in HEK293 cells coexpressing macrophage scavenger receptor | J Med Chem 56: 3943-58 (2013) Article DOI: 10.1021/jm4001538 BindingDB Entry DOI: 10.7270/Q21C1Z7T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium-dependent serotonin transporter (Homo sapiens (Human)) | BDBM50432573 (CHEMBL2347170) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 24 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ Libre de Bruxelles Curated by ChEMBL | Assay Description Inhibition of serotonin reuptake at human SERT expressed in HEK293 cells coexpressing macrophage scavenger receptor | J Med Chem 56: 3943-58 (2013) Article DOI: 10.1021/jm4001538 BindingDB Entry DOI: 10.7270/Q21C1Z7T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium-dependent serotonin transporter (Homo sapiens (Human)) | BDBM50432582 (CHEMBL205229) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Similars | Article PubMed | 29 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ Libre de Bruxelles Curated by ChEMBL | Assay Description Inhibition of serotonin reuptake at human SERT expressed in HEK293 cells coexpressing macrophage scavenger receptor | J Med Chem 56: 3943-58 (2013) Article DOI: 10.1021/jm4001538 BindingDB Entry DOI: 10.7270/Q21C1Z7T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium-dependent serotonin transporter (Homo sapiens (Human)) | BDBM50432579 (CHEMBL2347034) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 36 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ Libre de Bruxelles Curated by ChEMBL | Assay Description Inhibition of serotonin reuptake at human SERT expressed in HEK293 cells coexpressing macrophage scavenger receptor | J Med Chem 56: 3943-58 (2013) Article DOI: 10.1021/jm4001538 BindingDB Entry DOI: 10.7270/Q21C1Z7T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium-dependent serotonin transporter (Homo sapiens (Human)) | BDBM50432578 (CHEMBL2347165) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 50 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ Libre de Bruxelles Curated by ChEMBL | Assay Description Inhibition of human SERT expressed in HEK293 cells assessed as reduction in [3]5-HT uptake | Eur J Med Chem 123: 746-762 (2016) Article DOI: 10.1016/j.ejmech.2016.07.053 BindingDB Entry DOI: 10.7270/Q2FQ9ZMZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium-dependent serotonin transporter (Homo sapiens (Human)) | BDBM50432578 (CHEMBL2347165) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 53 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ Libre de Bruxelles Curated by ChEMBL | Assay Description Inhibition of serotonin reuptake at human SERT expressed in HEK293 cells coexpressing macrophage scavenger receptor | J Med Chem 56: 3943-58 (2013) Article DOI: 10.1021/jm4001538 BindingDB Entry DOI: 10.7270/Q21C1Z7T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium-dependent serotonin transporter (Homo sapiens (Human)) | BDBM50432576 (CHEMBL2347167) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 62 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ Libre de Bruxelles Curated by ChEMBL | Assay Description Inhibition of serotonin reuptake at human SERT expressed in HEK293 cells coexpressing macrophage scavenger receptor | J Med Chem 56: 3943-58 (2013) Article DOI: 10.1021/jm4001538 BindingDB Entry DOI: 10.7270/Q21C1Z7T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium-dependent serotonin transporter (Homo sapiens (Human)) | BDBM50432571 (CHEMBL2346670) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | 174 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ Libre de Bruxelles Curated by ChEMBL | Assay Description Inhibition of serotonin reuptake at human SERT expressed in HEK293 cells coexpressing macrophage scavenger receptor | J Med Chem 56: 3943-58 (2013) Article DOI: 10.1021/jm4001538 BindingDB Entry DOI: 10.7270/Q21C1Z7T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium-dependent serotonin transporter (Homo sapiens (Human)) | BDBM50432566 (CHEMBL2347179) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 184 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ Libre de Bruxelles Curated by ChEMBL | Assay Description Inhibition of serotonin reuptake at human SERT expressed in HEK293 cells coexpressing macrophage scavenger receptor | J Med Chem 56: 3943-58 (2013) Article DOI: 10.1021/jm4001538 BindingDB Entry DOI: 10.7270/Q21C1Z7T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium-dependent serotonin transporter (Homo sapiens (Human)) | BDBM50432568 (CHEMBL2347177) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 212 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ Libre de Bruxelles Curated by ChEMBL | Assay Description Inhibition of serotonin reuptake at human SERT expressed in HEK293 cells coexpressing macrophage scavenger receptor | J Med Chem 56: 3943-58 (2013) Article DOI: 10.1021/jm4001538 BindingDB Entry DOI: 10.7270/Q21C1Z7T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium-dependent serotonin transporter (Homo sapiens (Human)) | BDBM50432572 (CHEMBL2347171) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 539 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ Libre de Bruxelles Curated by ChEMBL | Assay Description Inhibition of serotonin reuptake at human SERT expressed in HEK293 cells coexpressing macrophage scavenger receptor | J Med Chem 56: 3943-58 (2013) Article DOI: 10.1021/jm4001538 BindingDB Entry DOI: 10.7270/Q21C1Z7T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium-dependent serotonin transporter (Homo sapiens (Human)) | BDBM50432565 (CHEMBL2347181) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 631 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ Libre de Bruxelles Curated by ChEMBL | Assay Description Inhibition of serotonin reuptake at human SERT expressed in HEK293 cells coexpressing macrophage scavenger receptor | J Med Chem 56: 3943-58 (2013) Article DOI: 10.1021/jm4001538 BindingDB Entry DOI: 10.7270/Q21C1Z7T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium-dependent serotonin transporter (Homo sapiens (Human)) | BDBM50206364 (CHEMBL3933129) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 800 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ Libre de Bruxelles Curated by ChEMBL | Assay Description Inhibition of human SERT expressed in HEK293 cells assessed as reduction in [3]5-HT uptake | Eur J Med Chem 123: 746-762 (2016) Article DOI: 10.1016/j.ejmech.2016.07.053 BindingDB Entry DOI: 10.7270/Q2FQ9ZMZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium-dependent serotonin transporter (Homo sapiens (Human)) | BDBM50206372 (CHEMBL3920217) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL MMDB PC cid PC sid UniChem Similars | Article PubMed | 1.10E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ Libre de Bruxelles Curated by ChEMBL | Assay Description Inhibition of human SERT expressed in HEK293 cells assessed as reduction in [3]5-HT uptake | Eur J Med Chem 123: 746-762 (2016) Article DOI: 10.1016/j.ejmech.2016.07.053 BindingDB Entry DOI: 10.7270/Q2FQ9ZMZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium-dependent serotonin transporter (Homo sapiens (Human)) | BDBM50206360 (CHEMBL3960919) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 1.40E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ Libre de Bruxelles Curated by ChEMBL | Assay Description Inhibition of human SERT expressed in HEK293 cells assessed as reduction in [3]5-HT uptake | Eur J Med Chem 123: 746-762 (2016) Article DOI: 10.1016/j.ejmech.2016.07.053 BindingDB Entry DOI: 10.7270/Q2FQ9ZMZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Myeloperoxidase (Homo sapiens (Human)) | BDBM50432573 (CHEMBL2347170) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 3 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ Libre de Bruxelles Curated by ChEMBL | Assay Description Inhibition of human recombinant MPO-mediated taurine chlorination after 5 mins by microplate assay | J Med Chem 56: 3943-58 (2013) Article DOI: 10.1021/jm4001538 BindingDB Entry DOI: 10.7270/Q21C1Z7T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Myeloperoxidase (Homo sapiens (Human)) | BDBM50432575 (CHEMBL2347168) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 4 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ Libre de Bruxelles Curated by ChEMBL | Assay Description Inhibition of human recombinant MPO-mediated taurine chlorination after 5 mins by microplate assay | J Med Chem 56: 3943-58 (2013) Article DOI: 10.1021/jm4001538 BindingDB Entry DOI: 10.7270/Q21C1Z7T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Myeloperoxidase (Homo sapiens (Human)) | BDBM50332590 (5-(5-fluoro-1H-indol-3-yl)pentan-1-amine | CHEMBL1...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 5 | n/a | n/a | n/a | n/a | n/a | n/a |
Universite£? Libre de Bruxelles Curated by ChEMBL | Assay Description Inhibition of recombinant MPO mediated LDL oxidation using MPO/Cl-/H2O2 system | J Med Chem 53: 8747-59 (2010) Article DOI: 10.1021/jm1009988 BindingDB Entry DOI: 10.7270/Q24T6JNJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Myeloperoxidase (Homo sapiens (Human)) | BDBM50432568 (CHEMBL2347177) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 5 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ Libre de Bruxelles Curated by ChEMBL | Assay Description Inhibition of human recombinant MPO-mediated taurine chlorination after 5 mins by microplate assay | J Med Chem 56: 3943-58 (2013) Article DOI: 10.1021/jm4001538 BindingDB Entry DOI: 10.7270/Q21C1Z7T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Myeloperoxidase (Homo sapiens (Human)) | BDBM50332590 (5-(5-fluoro-1H-indol-3-yl)pentan-1-amine | CHEMBL1...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 5 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ Libre de Bruxelles Curated by ChEMBL | Assay Description Inhibition of recombinant MPO (unknown origin) assessed as reduction in taurine chloramine production preincubated with enzyme and taurine followed b... | J Med Chem 60: 6563-6586 (2017) Article DOI: 10.1021/acs.jmedchem.7b00285 BindingDB Entry DOI: 10.7270/Q27D2XD7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Myeloperoxidase (Homo sapiens (Human)) | BDBM50238843 (CHEMBL4068067) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | 5 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ Libre de Bruxelles Curated by ChEMBL | Assay Description Inhibition of recombinant MPO (unknown origin) assessed as reduction in taurine chloramine production preincubated with enzyme and taurine followed b... | J Med Chem 60: 6563-6586 (2017) Article DOI: 10.1021/acs.jmedchem.7b00285 BindingDB Entry DOI: 10.7270/Q27D2XD7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Myeloperoxidase (Homo sapiens (Human)) | BDBM50432573 (CHEMBL2347170) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 6 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ Libre de Bruxelles Curated by ChEMBL | Assay Description Inhibition of human recombinant MPO-mediated LDL oxidation after 5 mins by ELISA | J Med Chem 56: 3943-58 (2013) Article DOI: 10.1021/jm4001538 BindingDB Entry DOI: 10.7270/Q21C1Z7T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Myeloperoxidase (Homo sapiens (Human)) | BDBM50432580 (CHEMBL2347032) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 6 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ Libre de Bruxelles Curated by ChEMBL | Assay Description Inhibition of human recombinant MPO-mediated taurine chlorination after 5 mins by microplate assay | J Med Chem 56: 3943-58 (2013) Article DOI: 10.1021/jm4001538 BindingDB Entry DOI: 10.7270/Q21C1Z7T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Myeloperoxidase (Homo sapiens (Human)) | BDBM50432575 (CHEMBL2347168) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 8 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ Libre de Bruxelles Curated by ChEMBL | Assay Description Inhibition of human recombinant MPO-mediated LDL oxidation after 5 mins by ELISA | J Med Chem 56: 3943-58 (2013) Article DOI: 10.1021/jm4001538 BindingDB Entry DOI: 10.7270/Q21C1Z7T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Myeloperoxidase (Homo sapiens (Human)) | BDBM50332589 (4-(5-fluoro-1H-indol-3-yl)butan-1-amine | CHEMBL16...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 8 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ Libre de Bruxelles Curated by ChEMBL | Assay Description In vitro antagonist activity against rat prostatic androgen receptor (AR) | J Med Chem 60: 6563-6586 (2017) Article DOI: 10.1021/acs.jmedchem.7b00285 BindingDB Entry DOI: 10.7270/Q27D2XD7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Myeloperoxidase (Homo sapiens (Human)) | BDBM50332590 (5-(5-fluoro-1H-indol-3-yl)pentan-1-amine | CHEMBL1...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 8 | n/a | n/a | n/a | n/a | n/a | n/a |
Universite£? Libre de Bruxelles Curated by ChEMBL | Assay Description Inhibition of recombinant MPO mediated taurine chlorination by microplate reader method | J Med Chem 53: 8747-59 (2010) Article DOI: 10.1021/jm1009988 BindingDB Entry DOI: 10.7270/Q24T6JNJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Myeloperoxidase (Homo sapiens (Human)) | BDBM50432577 (CHEMBL2347166) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 10 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ Libre de Bruxelles Curated by ChEMBL | Assay Description Inhibition of human recombinant MPO-mediated taurine chlorination after 5 mins by microplate assay | J Med Chem 56: 3943-58 (2013) Article DOI: 10.1021/jm4001538 BindingDB Entry DOI: 10.7270/Q21C1Z7T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Myeloperoxidase (Homo sapiens (Human)) | BDBM50432576 (CHEMBL2347167) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 10 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ Libre de Bruxelles Curated by ChEMBL | Assay Description Inhibition of human recombinant MPO-mediated taurine chlorination after 5 mins by microplate assay | J Med Chem 56: 3943-58 (2013) Article DOI: 10.1021/jm4001538 BindingDB Entry DOI: 10.7270/Q21C1Z7T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Myeloperoxidase (Homo sapiens (Human)) | BDBM50432569 (CHEMBL2347176) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 11 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ Libre de Bruxelles Curated by ChEMBL | Assay Description Inhibition of human recombinant MPO-mediated taurine chlorination after 5 mins by microplate assay | J Med Chem 56: 3943-58 (2013) Article DOI: 10.1021/jm4001538 BindingDB Entry DOI: 10.7270/Q21C1Z7T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Myeloperoxidase (Homo sapiens (Human)) | BDBM50332589 (4-(5-fluoro-1H-indol-3-yl)butan-1-amine | CHEMBL16...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 12 | n/a | n/a | n/a | n/a | n/a | n/a |
Universite£? Libre de Bruxelles Curated by ChEMBL | Assay Description Inhibition of recombinant MPO mediated LDL oxidation using MPO/Cl-/H2O2 system | J Med Chem 53: 8747-59 (2010) Article DOI: 10.1021/jm1009988 BindingDB Entry DOI: 10.7270/Q24T6JNJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Myeloperoxidase (Homo sapiens (Human)) | BDBM50432578 (CHEMBL2347165) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 13 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ Libre de Bruxelles Curated by ChEMBL | Assay Description Inhibition of MPO chlorination activity (unknown origin) assessed as taurine chloramine formation after 5 mins in presence of H2O2/Cl- by HTS method | Eur J Med Chem 123: 746-762 (2016) Article DOI: 10.1016/j.ejmech.2016.07.053 BindingDB Entry DOI: 10.7270/Q2FQ9ZMZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Myeloperoxidase (Homo sapiens (Human)) | BDBM50432578 (CHEMBL2347165) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 13 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ Libre de Bruxelles Curated by ChEMBL | Assay Description Inhibition of human recombinant MPO-mediated taurine chlorination after 5 mins by microplate assay | J Med Chem 56: 3943-58 (2013) Article DOI: 10.1021/jm4001538 BindingDB Entry DOI: 10.7270/Q21C1Z7T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Myeloperoxidase (Homo sapiens (Human)) | BDBM50432571 (CHEMBL2346670) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | 14 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ Libre de Bruxelles Curated by ChEMBL | Assay Description Inhibition of human recombinant MPO-mediated taurine chlorination after 5 mins by microplate assay | J Med Chem 56: 3943-58 (2013) Article DOI: 10.1021/jm4001538 BindingDB Entry DOI: 10.7270/Q21C1Z7T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Myeloperoxidase (Homo sapiens (Human)) | BDBM50332589 (4-(5-fluoro-1H-indol-3-yl)butan-1-amine | CHEMBL16...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 15 | n/a | n/a | n/a | n/a | n/a | n/a |
Universite£? Libre de Bruxelles Curated by ChEMBL | Assay Description Inhibition of recombinant MPO mediated taurine chlorination by microplate reader method | J Med Chem 53: 8747-59 (2010) Article DOI: 10.1021/jm1009988 BindingDB Entry DOI: 10.7270/Q24T6JNJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Myeloperoxidase (Homo sapiens (Human)) | BDBM50332586 (CHEMBL1630737 | N-(3-(5-fluoro-1H-indol-3-yl)propy...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 17 | n/a | n/a | n/a | n/a | n/a | n/a |
Universite£? Libre de Bruxelles Curated by ChEMBL | Assay Description Inhibition of recombinant MPO mediated LDL oxidation using MPO/Cl-/H2O2 system | J Med Chem 53: 8747-59 (2010) Article DOI: 10.1021/jm1009988 BindingDB Entry DOI: 10.7270/Q24T6JNJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Myeloperoxidase (Homo sapiens (Human)) | BDBM50432565 (CHEMBL2347181) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 18 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ Libre de Bruxelles Curated by ChEMBL | Assay Description Inhibition of cathepsin D. | J Med Chem 60: 6563-6586 (2017) Article DOI: 10.1021/acs.jmedchem.7b00285 BindingDB Entry DOI: 10.7270/Q27D2XD7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Myeloperoxidase (Homo sapiens (Human)) | BDBM50432565 (CHEMBL2347181) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 18 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ Libre de Bruxelles Curated by ChEMBL | Assay Description Inhibition of human recombinant MPO-mediated taurine chlorination after 5 mins by microplate assay | J Med Chem 56: 3943-58 (2013) Article DOI: 10.1021/jm4001538 BindingDB Entry DOI: 10.7270/Q21C1Z7T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Myeloperoxidase (Homo sapiens (Human)) | BDBM50432565 (CHEMBL2347181) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 18 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ Libre de Bruxelles Curated by ChEMBL | Assay Description Inhibition of human recombinant MPO-mediated LDL oxidation after 5 mins by ELISA | J Med Chem 56: 3943-58 (2013) Article DOI: 10.1021/jm4001538 BindingDB Entry DOI: 10.7270/Q21C1Z7T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Myeloperoxidase (Homo sapiens (Human)) | BDBM22416 ((3S,4R)-3-[(1,3-benzodioxol-5-yloxy)methyl]-4-(4-f...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | PDB Article PubMed | n/a | n/a | 20 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ Libre de Bruxelles Curated by ChEMBL | Assay Description Inhibition of recombinant MPO (unknown origin) assessed as reduction in taurine chloramine production preincubated with enzyme and taurine followed b... | J Med Chem 60: 6563-6586 (2017) Article DOI: 10.1021/acs.jmedchem.7b00285 BindingDB Entry DOI: 10.7270/Q27D2XD7 | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Myeloperoxidase (Homo sapiens (Human)) | BDBM50432574 (CHEMBL2347169) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 21 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ Libre de Bruxelles Curated by ChEMBL | Assay Description Inhibition of human recombinant MPO-mediated LDL oxidation after 5 mins by ELISA | J Med Chem 56: 3943-58 (2013) Article DOI: 10.1021/jm4001538 BindingDB Entry DOI: 10.7270/Q21C1Z7T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Myeloperoxidase (Homo sapiens (Human)) | BDBM50432580 (CHEMBL2347032) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 21 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ Libre de Bruxelles Curated by ChEMBL | Assay Description Inhibition of human recombinant MPO-mediated LDL oxidation after 5 mins by ELISA | J Med Chem 56: 3943-58 (2013) Article DOI: 10.1021/jm4001538 BindingDB Entry DOI: 10.7270/Q21C1Z7T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Myeloperoxidase (Homo sapiens (Human)) | BDBM50432569 (CHEMBL2347176) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 21 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ Libre de Bruxelles Curated by ChEMBL | Assay Description Inhibition of human recombinant MPO-mediated LDL oxidation after 5 mins by ELISA | J Med Chem 56: 3943-58 (2013) Article DOI: 10.1021/jm4001538 BindingDB Entry DOI: 10.7270/Q21C1Z7T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Myeloperoxidase (Homo sapiens (Human)) | BDBM50432579 (CHEMBL2347034) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 22 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ Libre de Bruxelles Curated by ChEMBL | Assay Description Inhibition of human recombinant MPO-mediated taurine chlorination after 5 mins by microplate assay | J Med Chem 56: 3943-58 (2013) Article DOI: 10.1021/jm4001538 BindingDB Entry DOI: 10.7270/Q21C1Z7T | |||||||||||
More data for this Ligand-Target Pair |
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