Compile Data Set for Download or QSAR

Found 27 hits with Last Name = 'maloney' and Initial = 'pj'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Thromboxane-A synthase (Homo sapiens (Human))	BDBM50017914 (3-(1-Ethyl-5-pyridin-3-ylmethyl-1H-pyrrol-2-yl)-2-...) Show SMILES CCn1c(Cc2cccnc2)ccc1\C=C(\C)C(O)=O Show InChI InChI=1S/C16H18N2O2/c1-3-18-14(9-12(2)16(19)20)6-7-15(18)10-13-5-4-8-17-11-13/h4-9,11H,3,10H2,1-2H3,(H,19,20)/b12-9-	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	42	n/a	n/a	n/a	n/a	n/a	n/a
Syntex Research Curated by ChEMBL					Assay Description Inhibition of thromboxane A2 synthetase as reduced ADP-induced aggregation of human platelet rich plasma in the presence of pig aortal microsomes				J Med Chem 32: 890-7 (1989) BindingDB Entry DOI: 10.7270/Q26W993X
					More data for this Ligand-Target Pair
Thromboxane-A synthase (Homo sapiens (Human))	BDBM50017903 (3-(1-tert-Butyl-5-pyridin-3-ylmethyl-1H-pyrrol-3-y...) Show SMILES C\C(=C\c1cc(Cc2cccnc2)n(c1)C(C)(C)C)C(O)=O Show InChI InChI=1S/C18H22N2O2/c1-13(17(21)22)8-15-10-16(20(12-15)18(2,3)4)9-14-6-5-7-19-11-14/h5-8,10-12H,9H2,1-4H3,(H,21,22)/b13-8-	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	44	n/a	n/a	n/a	n/a	n/a	n/a
Syntex Research Curated by ChEMBL					Assay Description Inhibition of thromboxane A2 synthetase as reduced ADP-induced aggregation of human platelet rich plasma in the presence of pig aortal microsomes				J Med Chem 32: 890-7 (1989) BindingDB Entry DOI: 10.7270/Q26W993X
					More data for this Ligand-Target Pair
Thromboxane-A synthase (Homo sapiens (Human))	BDBM50017905 (2-Methyl-3-(1-methyl-5-pyridin-3-ylmethyl-1H-pyrro...) Show SMILES C\C(=C\c1ccc(Cc2cccnc2)n1C)C(O)=O Show InChI InChI=1S/C15H16N2O2/c1-11(15(18)19)8-13-5-6-14(17(13)2)9-12-4-3-7-16-10-12/h3-8,10H,9H2,1-2H3,(H,18,19)/b11-8-	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
Syntex Research Curated by ChEMBL					Assay Description Inhibition of thromboxane A2 synthetase as reduced ADP-induced aggregation of human platelet rich plasma in the presence of pig aortal microsomes				J Med Chem 32: 890-7 (1989) BindingDB Entry DOI: 10.7270/Q26W993X
					More data for this Ligand-Target Pair
cGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B (Homo sapiens (Human))	BDBM50000334 (6,7-Dichloro-1,5-dihydro-imidazo[2,1-b]quinazolin-...) Show SMILES Clc1ccc2N=C3NC(=O)CN3Cc2c1Cl |t:5| Show InChI InChI=1S/C10H7Cl2N3O/c11-6-1-2-7-5(9(6)12)3-15-4-8(16)14-10(15)13-7/h1-2H,3-4H2,(H,13,14,16)	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE PC cid PC sid PDB UniChem Patents Similars	PDB PubMed	n/a	n/a	82	n/a	n/a	n/a	n/a	n/a	n/a
Syntex Research Curated by ChEMBL					Assay Description Inhibition of human blood platelet c-AMP phosphodiesterase				J Med Chem 35: 620-8 (1992) BindingDB Entry DOI: 10.7270/Q2PZ57SK
					More data for this Ligand-Target Pair				3D Structure (crystal)
Thromboxane-A synthase (Homo sapiens (Human))	BDBM50000308 (6-(Imidazol-1-yl-phenyl-methyl)-3,4-dihydro-1H-qui...) Show SMILES O=C1CCc2cc(ccc2N1)C(c1ccccc1)n1ccnc1 Show InChI InChI=1S/C19H17N3O/c23-18-9-7-15-12-16(6-8-17(15)21-18)19(22-11-10-20-13-22)14-4-2-1-3-5-14/h1-6,8,10-13,19H,7,9H2,(H,21,23)	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	PubMed	n/a	n/a	350	n/a	n/a	n/a	n/a	n/a	n/a
Syntex Research Curated by ChEMBL					Assay Description Compound was evaluated for the inhibition of human blood platelet,thromboxane A2 synthase				J Med Chem 35: 620-8 (1992) BindingDB Entry DOI: 10.7270/Q2PZ57SK
					More data for this Ligand-Target Pair
Thromboxane-A synthase (Homo sapiens (Human))	BDBM50000318 (6-(2-Imidazol-1-yl-vinyl)-1H-quinolin-2-one | CHEM...) Show SMILES O=c1ccc2cc(\C=C\n3ccnc3)ccc2[nH]1 Show InChI InChI=1S/C14H11N3O/c18-14-4-2-12-9-11(1-3-13(12)16-14)5-7-17-8-6-15-10-17/h1-10H,(H,16,18)/b7-5+	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	380	n/a	n/a	n/a	n/a	n/a	n/a
Syntex Research Curated by ChEMBL					Assay Description Compound was evaluated for the inhibition of human blood platelet,thromboxane A2 synthase				J Med Chem 35: 620-8 (1992) BindingDB Entry DOI: 10.7270/Q2PZ57SK
					More data for this Ligand-Target Pair
Thromboxane-A synthase (Homo sapiens (Human))	BDBM50000306 (6-Pyridin-3-yl-3,4-dihydro-1H-quinolin-2-one | 6-P...) Show SMILES O=C1CCc2cc(ccc2N1)-c1cccnc1 Show InChI InChI=1S/C14H12N2O/c17-14-6-4-11-8-10(3-5-13(11)16-14)12-2-1-7-15-9-12/h1-3,5,7-9H,4,6H2,(H,16,17)	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	540	n/a	n/a	n/a	n/a	n/a	n/a
Syntex Research Curated by ChEMBL					Assay Description Compound was evaluated for the inhibition of human blood platelet,thromboxane A2 synthase				J Med Chem 35: 620-8 (1992) BindingDB Entry DOI: 10.7270/Q2PZ57SK
					More data for this Ligand-Target Pair
Thromboxane-A synthase (Homo sapiens (Human))	BDBM50017909 (3-(5-Imidazol-1-ylmethyl-1-methyl-1H-pyrrol-2-yl)-...) Show SMILES C\C(=C\c1ccc(Cn2ccnc2)n1C)C(O)=O Show InChI InChI=1S/C13H15N3O2/c1-10(13(17)18)7-11-3-4-12(15(11)2)8-16-6-5-14-9-16/h3-7,9H,8H2,1-2H3,(H,17,18)/b10-7-	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Syntex Research Curated by ChEMBL					Assay Description Inhibition of thromboxane A2 synthetase as reduced ADP-induced aggregation of human platelet rich plasma in the presence of pig aortal microsomes				J Med Chem 32: 890-7 (1989) BindingDB Entry DOI: 10.7270/Q26W993X
					More data for this Ligand-Target Pair
Thromboxane-A synthase (Homo sapiens (Human))	BDBM50000310 (6-(2-Imidazol-1-yl-vinyl)-3,4-dihydro-1H-quinolin-...) Show SMILES O=C1CCc2cc(\C=C\n3ccnc3)ccc2N1 Show InChI InChI=1S/C14H13N3O/c18-14-4-2-12-9-11(1-3-13(12)16-14)5-7-17-8-6-15-10-17/h1,3,5-10H,2,4H2,(H,16,18)/b7-5+	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Syntex Research Curated by ChEMBL					Assay Description Compound was evaluated for the inhibition of human blood platelet thromboxane A2 synthase				J Med Chem 35: 620-8 (1992) BindingDB Entry DOI: 10.7270/Q2PZ57SK
					More data for this Ligand-Target Pair
Thromboxane-A synthase (Homo sapiens (Human))	BDBM50017896 ((E)-3-(4-Imidazol-1-ylmethyl-phenyl)-acrylic acid ...) Show SMILES OC(=O)\C=C\c1ccc(Cn2ccnc2)cc1 Show InChI InChI=1S/C13H12N2O2/c16-13(17)6-5-11-1-3-12(4-2-11)9-15-8-7-14-10-15/h1-8,10H,9H2,(H,16,17)/b6-5+	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	1.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
Syntex Research Curated by ChEMBL					Assay Description Inhibition of thromboxane A2 synthetase as reduced ADP-induced aggregation of human platelet rich plasma in the presence of pig aortal microsomes				J Med Chem 32: 890-7 (1989) BindingDB Entry DOI: 10.7270/Q26W993X
					More data for this Ligand-Target Pair
Thromboxane-A synthase (Homo sapiens (Human))	BDBM50017912 (3-(5-Imidazol-1-ylmethyl-1-methyl-1H-pyrrol-3-yl)-...) Show SMILES C\C(=C/c1cc(Cn2ccnc2)n(C)c1)C(O)=O Show InChI InChI=1S/C13H15N3O2/c1-10(13(17)18)5-11-6-12(15(2)7-11)8-16-4-3-14-9-16/h3-7,9H,8H2,1-2H3,(H,17,18)/b10-5+	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
Syntex Research Curated by ChEMBL					Assay Description Inhibition of thromboxane A2 synthetase as reduced ADP-induced aggregation of human platelet rich plasma in the presence of pig aortal microsomes				J Med Chem 32: 890-7 (1989) BindingDB Entry DOI: 10.7270/Q26W993X
					More data for this Ligand-Target Pair
Thromboxane-A synthase (Homo sapiens (Human))	BDBM50000309 (6-Imidazol-1-yl-3,4-dihydro-1H-quinolin-2-one | CH...) Show SMILES O=C1CCc2cc(ccc2N1)-n1ccnc1 Show InChI InChI=1S/C12H11N3O/c16-12-4-1-9-7-10(2-3-11(9)14-12)15-6-5-13-8-15/h2-3,5-8H,1,4H2,(H,14,16)	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents	PubMed	n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Syntex Research Curated by ChEMBL					Assay Description Compound was evaluated for the inhibition of human blood platelet,thromboxane A2 synthase				J Med Chem 35: 620-8 (1992) BindingDB Entry DOI: 10.7270/Q2PZ57SK
					More data for this Ligand-Target Pair
Thromboxane-A synthase (Homo sapiens (Human))	BDBM50017915 (3-(1-Isopropyl-5-pyridin-3-ylmethyl-1H-pyrrol-2-yl...) Show SMILES CC(C)n1c(Cc2cccnc2)ccc1\C=C(\C)C(O)=O Show InChI InChI=1S/C17H20N2O2/c1-12(2)19-15(9-13(3)17(20)21)6-7-16(19)10-14-5-4-8-18-11-14/h4-9,11-12H,10H2,1-3H3,(H,20,21)/b13-9-	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Syntex Research Curated by ChEMBL					Assay Description Inhibition of thromboxane A2 synthetase as reduced ADP-induced aggregation of human platelet rich plasma in the presence of pig aortal microsomes				J Med Chem 32: 890-7 (1989) BindingDB Entry DOI: 10.7270/Q26W993X
					More data for this Ligand-Target Pair
Thromboxane-A synthase (Homo sapiens (Human))	BDBM50017908 (3-(5-Imidazol-1-ylmethyl-1-methyl-1H-pyrrol-2-yl)-...) Show SMILES Cn1c(Cn2ccnc2)ccc1\C=C\C(O)=O Show InChI InChI=1S/C12H13N3O2/c1-14-10(4-5-12(16)17)2-3-11(14)8-15-7-6-13-9-15/h2-7,9H,8H2,1H3,(H,16,17)/b5-4+	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	3.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
Syntex Research Curated by ChEMBL					Assay Description Inhibition of thromboxane A2 synthetase as reduced ADP-induced aggregation of human platelet rich plasma in the presence of pig aortal microsomes				J Med Chem 32: 890-7 (1989) BindingDB Entry DOI: 10.7270/Q26W993X
					More data for this Ligand-Target Pair
cGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B (Homo sapiens (Human))	BDBM50000318 (6-(2-Imidazol-1-yl-vinyl)-1H-quinolin-2-one | CHEM...) Show SMILES O=c1ccc2cc(\C=C\n3ccnc3)ccc2[nH]1 Show InChI InChI=1S/C14H11N3O/c18-14-4-2-12-9-11(1-3-13(12)16-14)5-7-17-8-6-15-10-17/h1-10H,(H,16,18)/b7-5+	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	4.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Syntex Research Curated by ChEMBL					Assay Description Inhibition of human blood platelet c-AMP phosphodiesterase				J Med Chem 35: 620-8 (1992) BindingDB Entry DOI: 10.7270/Q2PZ57SK
					More data for this Ligand-Target Pair
cGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B (Homo sapiens (Human))	BDBM50000306 (6-Pyridin-3-yl-3,4-dihydro-1H-quinolin-2-one | 6-P...) Show SMILES O=C1CCc2cc(ccc2N1)-c1cccnc1 Show InChI InChI=1S/C14H12N2O/c17-14-6-4-11-8-10(3-5-13(11)16-14)12-2-1-7-15-9-12/h1-3,5,7-9H,4,6H2,(H,16,17)	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	4.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
Syntex Research Curated by ChEMBL					Assay Description Inhibition of human blood platelet c-AMP phosphodiesterase				J Med Chem 35: 620-8 (1992) BindingDB Entry DOI: 10.7270/Q2PZ57SK
					More data for this Ligand-Target Pair
Thromboxane-A synthase (Homo sapiens (Human))	BDBM50017910 (3-(5-Imidazol-1-ylmethyl-1-methyl-1H-pyrrol-3-yl)-...) Show SMILES Cn1cc(\C=C\C(O)=O)cc1Cn1ccnc1 Show InChI InChI=1S/C12H13N3O2/c1-14-7-10(2-3-12(16)17)6-11(14)8-15-5-4-13-9-15/h2-7,9H,8H2,1H3,(H,16,17)/b3-2+	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	4.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
Syntex Research Curated by ChEMBL					Assay Description Inhibition of thromboxane A2 synthetase as reduced ADP-induced aggregation of human platelet rich plasma in the presence of pig aortal microsomes				J Med Chem 32: 890-7 (1989) BindingDB Entry DOI: 10.7270/Q26W993X
					More data for this Ligand-Target Pair
cGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B (Homo sapiens (Human))	BDBM50000315 ((CI-914)6-(4-Imidazol-1-yl-phenyl)-4,5-dihydro-2H-...) Show SMILES O=C1CCC(=NN1)c1ccc(cc1)-n1ccnc1 |c:4| Show InChI InChI=1S/C13H12N4O/c18-13-6-5-12(15-16-13)10-1-3-11(4-2-10)17-8-7-14-9-17/h1-4,7-9H,5-6H2,(H,16,18)	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	4.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
Syntex Research Curated by ChEMBL					Assay Description Inhibition of human blood platelet c-AMP phosphodiesterase				J Med Chem 35: 620-8 (1992) BindingDB Entry DOI: 10.7270/Q2PZ57SK
					More data for this Ligand-Target Pair
cGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B (Homo sapiens (Human))	BDBM50000310 (6-(2-Imidazol-1-yl-vinyl)-3,4-dihydro-1H-quinolin-...) Show SMILES O=C1CCc2cc(\C=C\n3ccnc3)ccc2N1 Show InChI InChI=1S/C14H13N3O/c18-14-4-2-12-9-11(1-3-13(12)16-14)5-7-17-8-6-15-10-17/h1,3,5-10H,2,4H2,(H,16,18)/b7-5+	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	6.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
Syntex Research Curated by ChEMBL					Assay Description Inhibition of human blood platelet c-AMP phosphodiesterase				J Med Chem 35: 620-8 (1992) BindingDB Entry DOI: 10.7270/Q2PZ57SK
					More data for this Ligand-Target Pair
Thromboxane-A synthase (Homo sapiens (Human))	BDBM50017913 (2-(5-Imidazol-1-ylmethyl-1-methyl-1H-pyrrol-2-yl)-...) Show SMILES COC(=O)[C@@H]1CC1c1ccc(Cn2ccnc2)n1C Show InChI InChI=1S/C14H17N3O2/c1-16-10(8-17-6-5-15-9-17)3-4-13(16)11-7-12(11)14(18)19-2/h3-6,9,11-12H,7-8H2,1-2H3/t11?,12-/m1/s1	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	9.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Syntex Research Curated by ChEMBL					Assay Description Inhibition of thromboxane A2 synthetase as reduced ADP-induced aggregation of human platelet rich plasma in the presence of pig aortal microsomes				J Med Chem 32: 890-7 (1989) BindingDB Entry DOI: 10.7270/Q26W993X
					More data for this Ligand-Target Pair
Thromboxane-A synthase (Homo sapiens (Human))	BDBM50017901 (3-(5-Imidazol-1-ylmethyl-1H-pyrrol-2-yl)-2-methyl-...) Show SMILES C\C(=C/c1ccc(Cn2ccnc2)[nH]1)C(O)=O Show InChI InChI=1S/C12H13N3O2/c1-9(12(16)17)6-10-2-3-11(14-10)7-15-5-4-13-8-15/h2-6,8,14H,7H2,1H3,(H,16,17)/b9-6+	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	9.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Syntex Research Curated by ChEMBL					Assay Description Inhibition of thromboxane A2 synthetase as reduced ADP-induced aggregation of human platelet rich plasma in the presence of pig aortal microsomes				J Med Chem 32: 890-7 (1989) BindingDB Entry DOI: 10.7270/Q26W993X
					More data for this Ligand-Target Pair
cGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B (Homo sapiens (Human))	BDBM50000328 (6-(1-Imidazol-1-ylmethyl-hexyl)-3,4-dihydro-1H-qui...) Show SMILES CCCCCC(Cn1ccnc1)c1ccc2NC(=O)CCc2c1 Show InChI InChI=1S/C19H25N3O/c1-2-3-4-5-17(13-22-11-10-20-14-22)15-6-8-18-16(12-15)7-9-19(23)21-18/h6,8,10-12,14,17H,2-5,7,9,13H2,1H3,(H,21,23)	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	PubMed	n/a	n/a	1.40E+4	n/a	n/a	n/a	n/a	n/a	n/a
Syntex Research Curated by ChEMBL					Assay Description Inhibition of human blood platelet c-AMP phosphodiesterase				J Med Chem 35: 620-8 (1992) BindingDB Entry DOI: 10.7270/Q2PZ57SK
					More data for this Ligand-Target Pair
cGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B (Homo sapiens (Human))	BDBM50000309 (6-Imidazol-1-yl-3,4-dihydro-1H-quinolin-2-one | CH...) Show SMILES O=C1CCc2cc(ccc2N1)-n1ccnc1 Show InChI InChI=1S/C12H11N3O/c16-12-4-1-9-7-10(2-3-11(9)14-12)15-6-5-13-8-15/h2-3,5-8H,1,4H2,(H,14,16)	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents	PubMed	n/a	n/a	1.60E+4	n/a	n/a	n/a	n/a	n/a	n/a
Syntex Research Curated by ChEMBL					Assay Description Inhibition of human blood platelet c-AMP phosphodiesterase				J Med Chem 35: 620-8 (1992) BindingDB Entry DOI: 10.7270/Q2PZ57SK
					More data for this Ligand-Target Pair
Thromboxane-A synthase (Homo sapiens (Human))	BDBM50017898 (2-Methyl-3-(1-phenyl-5-pyridin-3-ylmethyl-1H-pyrro...) Show SMILES C\C(=C\c1ccc(Cc2cccnc2)n1-c1ccccc1)C(O)=O Show InChI InChI=1S/C20H18N2O2/c1-15(20(23)24)12-18-9-10-19(13-16-6-5-11-21-14-16)22(18)17-7-3-2-4-8-17/h2-12,14H,13H2,1H3,(H,23,24)/b15-12-	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.40E+4	n/a	n/a	n/a	n/a	n/a	n/a
Syntex Research Curated by ChEMBL					Assay Description Inhibition of thromboxane A2 synthetase as reduced ADP-induced aggregation of human platelet rich plasma in the presence of pig aortal microsomes				J Med Chem 32: 890-7 (1989) BindingDB Entry DOI: 10.7270/Q26W993X
					More data for this Ligand-Target Pair
Thromboxane-A synthase (Homo sapiens (Human))	BDBM50000328 (6-(1-Imidazol-1-ylmethyl-hexyl)-3,4-dihydro-1H-qui...) Show SMILES CCCCCC(Cn1ccnc1)c1ccc2NC(=O)CCc2c1 Show InChI InChI=1S/C19H25N3O/c1-2-3-4-5-17(13-22-11-10-20-14-22)15-6-8-18-16(12-15)7-9-19(23)21-18/h6,8,10-12,14,17H,2-5,7,9,13H2,1H3,(H,21,23)	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	PubMed	n/a	n/a	2.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
Syntex Research Curated by ChEMBL					Assay Description Compound was evaluated for the inhibition of human blood platelet thromboxane A2 synthase				J Med Chem 35: 620-8 (1992) BindingDB Entry DOI: 10.7270/Q2PZ57SK
					More data for this Ligand-Target Pair
cGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B (Homo sapiens (Human))	BDBM50000308 (6-(Imidazol-1-yl-phenyl-methyl)-3,4-dihydro-1H-qui...) Show SMILES O=C1CCc2cc(ccc2N1)C(c1ccccc1)n1ccnc1 Show InChI InChI=1S/C19H17N3O/c23-18-9-7-15-12-16(6-8-17(15)21-18)19(22-11-10-20-13-22)14-4-2-1-3-5-14/h1-6,8,10-13,19H,7,9H2,(H,21,23)	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	PubMed	n/a	n/a	4.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Syntex Research Curated by ChEMBL					Assay Description Inhibition of human blood platelet c-AMP phosphodiesterase				J Med Chem 35: 620-8 (1992) BindingDB Entry DOI: 10.7270/Q2PZ57SK
					More data for this Ligand-Target Pair
Thromboxane-A synthase (Homo sapiens (Human))	BDBM50017907 (3-[1-(2,2-Dimethyl-propyl)-5-pyridin-3-ylmethyl-1H...) Show SMILES C\C(=C\c1ccc(Cc2cccnc2)n1CC(C)(C)C)C(O)=O Show InChI InChI=1S/C19H24N2O2/c1-14(18(22)23)10-16-7-8-17(21(16)13-19(2,3)4)11-15-6-5-9-20-12-15/h5-10,12H,11,13H2,1-4H3,(H,22,23)/b14-10-	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	7.80E+4	n/a	n/a	n/a	n/a	n/a	n/a
Syntex Research Curated by ChEMBL					Assay Description Inhibition of thromboxane A2 synthetase as reduced ADP-induced aggregation of human platelet rich plasma in the presence of pig aortal microsomes				J Med Chem 32: 890-7 (1989) BindingDB Entry DOI: 10.7270/Q26W993X
					More data for this Ligand-Target Pair