Compile Data Set for Download or QSAR

Found 651 hits with Last Name = 'yao' and Initial = 's'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Gag-Pol polyprotein [489-587] (Human immunodeficiency virus type 1)	BDBM50069330 ((S)-2-((S)-2-{(2R,5S)-2-Benzyl-5-[(S)-2-((S)-2-ben...) Show SMILES COC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](CC(O)[C@H](Cc1ccccc1)NC(=O)[C@H](C)NC(=O)[C@H](C)NC(=O)OCc1ccccc1)Cc1ccccc1)C(C)C)C(C)C Show InChI InChI=1S/C44H59N5O9/c1-27(2)37(42(54)49-38(28(3)4)43(55)57-7)48-41(53)34(23-31-17-11-8-12-18-31)25-36(50)35(24-32-19-13-9-14-20-32)47-40(52)29(5)45-39(51)30(6)46-44(56)58-26-33-21-15-10-16-22-33/h8-22,27-30,34-38,50H,23-26H2,1-7H3,(H,45,51)(H,46,56)(H,47,52)(H,48,53)(H,49,54)/t29-,30-,34+,35-,36?,37-,38-/m0/s1	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	0.400	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Inhibitory activity against HIV-1 Protease was determined				Bioorg Med Chem Lett 8: 699-704 (1999) BindingDB Entry DOI: 10.7270/Q20K27QJ
					More data for this Ligand-Target Pair
NAD-dependent protein deacetylase sirtuin-2 (Homo sapiens (Human))	BDBM50148827 (CHEMBL3769975) Show SMILES COc1ccc2ccccc2c1Cn1cnc2sc3CC(CCc3c2c1=O)NCc1cccnc1 Show InChI InChI=1S/C28H26N4O2S/c1-34-24-11-8-19-6-2-3-7-21(19)23(24)16-32-17-31-27-26(28(32)33)22-10-9-20(13-25(22)35-27)30-15-18-5-4-12-29-14-18/h2-8,11-12,14,17,20,30H,9-10,13,15-16H2,1H3	PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	620	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Imperial College Curated by ChEMBL					Assay Description Inhibition of recombinant human C-terminal His-tagged SIRT2 (50 to 389 end residues) expressed in Escherichia coli using tubulin-K40 peptide in prese...				J Med Chem 60: 1928-1945 (2017) Article DOI: 10.1021/acs.jmedchem.6b01690 BindingDB Entry DOI: 10.7270/Q23F4SP1
					More data for this Ligand-Target Pair
Sodium/nucleoside cotransporter 1 (Homo sapiens (Human))	BDBM14487 ((2R,3R,4S,5R)-2-(6-amino-9H-purin-9-yl)-5-(hydroxy...) Show SMILES Nc1ncnc2n(cnc12)[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1O Show InChI InChI=1S/C10H13N5O4/c11-8-5-9(13-2-12-8)15(3-14-5)10-7(18)6(17)4(1-16)19-10/h2-4,6-7,10,16-18H,1H2,(H2,11,12,13)/t4-,6-,7-,10-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Similars	Article PubMed	1.80E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Gilead Sciences, Inc. Curated by ChEMBL					Assay Description Binding affinity to recombinant human CNT1 expressed in Saccharomyces cerevisiae assessed as inhibition of [3H]-uridine transport after 15 mins by sc...				Drug Metab Dispos 41: 916-22 (2013) Article DOI: 10.1124/dmd.112.049858 BindingDB Entry DOI: 10.7270/Q21N82VJ
					More data for this Ligand-Target Pair
Solute carrier family 28 member 3 (Homo sapiens (Human))	BDBM14487 ((2R,3R,4S,5R)-2-(6-amino-9H-purin-9-yl)-5-(hydroxy...) Show SMILES Nc1ncnc2n(cnc12)[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1O Show InChI InChI=1S/C10H13N5O4/c11-8-5-9(13-2-12-8)15(3-14-5)10-7(18)6(17)4(1-16)19-10/h2-4,6-7,10,16-18H,1H2,(H2,11,12,13)/t4-,6-,7-,10-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Similars	DrugBank Article PubMed	2.10E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Gilead Sciences, Inc. Curated by ChEMBL					Assay Description Binding affinity to recombinant human CNT3 expressed in Saccharomyces cerevisiae assessed as inhibition of [3H]-uridine transport after 5 mins by sci...				Drug Metab Dispos 41: 916-22 (2013) Article DOI: 10.1124/dmd.112.049858 BindingDB Entry DOI: 10.7270/Q21N82VJ
					More data for this Ligand-Target Pair
Gag-Pol polyprotein [489-587] (Human immunodeficiency virus type 1)	BDBM50069332 ((S)-2-[(S)-2-((S)-2-{(S)-2-[(S)-2-((S)-2-tert-Buto...) Show SMILES COC(=O)[C@@H](NC(=S)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](C)NC(=O)[C@H](C)NC(=O)OC(C)(C)C)C(C)C)C(C)C Show InChI InChI=1S/C40H58N6O8S/c1-23(2)31(37(55)46-32(24(3)4)38(51)53-10)45-36(50)30(22-28-19-15-12-16-20-28)44-35(49)29(21-27-17-13-11-14-18-27)43-34(48)25(5)41-33(47)26(6)42-39(52)54-40(7,8)9/h11-20,23-26,29-32H,21-22H2,1-10H3,(H,41,47)(H,42,52)(H,43,48)(H,44,49)(H,45,50)(H,46,55)/t25-,26-,29-,30-,31-,32-/m0/s1	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	3.40E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Binding affinity was evaluated for competitive inhibition of HIV-1 Protease				Bioorg Med Chem Lett 8: 699-704 (1999) BindingDB Entry DOI: 10.7270/Q20K27QJ
					More data for this Ligand-Target Pair
Solute carrier family 28 member 3 (Homo sapiens (Human))	BDBM50088517 (CHEBI:16704 | Uridine) Show SMILES OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1ccc(=O)[nH]c1=O |r| Show InChI InChI=1S/C9H12N2O6/c12-3-4-6(14)7(15)8(17-4)11-2-1-5(13)10-9(11)16/h1-2,4,6-8,12,14-15H,3H2,(H,10,13,16)/t4-,6-,7-,8-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	3.40E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Gilead Sciences, Inc. Curated by ChEMBL					Assay Description Binding affinity to recombinant human CNT3 expressed in Saccharomyces cerevisiae assessed as inhibition of [3H]-uridine transport after 5 mins by sci...				Drug Metab Dispos 41: 916-22 (2013) Article DOI: 10.1124/dmd.112.049858 BindingDB Entry DOI: 10.7270/Q21N82VJ
					More data for this Ligand-Target Pair
Sodium/nucleoside cotransporter 1 (Homo sapiens (Human))	BDBM50088517 (CHEBI:16704 | Uridine) Show SMILES OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1ccc(=O)[nH]c1=O |r| Show InChI InChI=1S/C9H12N2O6/c12-3-4-6(14)7(15)8(17-4)11-2-1-5(13)10-9(11)16/h1-2,4,6-8,12,14-15H,3H2,(H,10,13,16)/t4-,6-,7-,8-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	5.20E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Gilead Sciences, Inc. Curated by ChEMBL					Assay Description Binding affinity to recombinant human CNT1 expressed in Saccharomyces cerevisiae assessed as inhibition of [3H]-uridine transport after 15 mins by sc...				Drug Metab Dispos 41: 916-22 (2013) Article DOI: 10.1124/dmd.112.049858 BindingDB Entry DOI: 10.7270/Q21N82VJ
					More data for this Ligand-Target Pair
Sodium/nucleoside cotransporter 2 (Homo sapiens (Human))	BDBM14487 ((2R,3R,4S,5R)-2-(6-amino-9H-purin-9-yl)-5-(hydroxy...) Show SMILES Nc1ncnc2n(cnc12)[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1O Show InChI InChI=1S/C10H13N5O4/c11-8-5-9(13-2-12-8)15(3-14-5)10-7(18)6(17)4(1-16)19-10/h2-4,6-7,10,16-18H,1H2,(H2,11,12,13)/t4-,6-,7-,10-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Similars	Article PubMed	5.30E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Gilead Sciences, Inc. Curated by ChEMBL					Assay Description Binding affinity to recombinant human CNT2 expressed in Saccharomyces cerevisiae assessed as inhibition of [3H]-uridine transport after 15 mins by sc...				Drug Metab Dispos 41: 916-22 (2013) Article DOI: 10.1124/dmd.112.049858 BindingDB Entry DOI: 10.7270/Q21N82VJ
					More data for this Ligand-Target Pair
Equilibrative nucleoside transporter 1 (Homo sapiens (Human))	BDBM50138530 ((2R,3R,5R)-2-Hydroxymethyl-5-{6-[(R)-(tetrahydro-f...) Show SMILES OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2c(N[C@@H]3CCOC3)ncnc12 Show InChI InChI=1S/C14H19N5O5/c20-3-8-10(21)11(22)14(24-8)19-6-17-9-12(15-5-16-13(9)19)18-7-1-2-23-4-7/h5-8,10-11,14,20-22H,1-4H2,(H,15,16,18)/t7?,8-,10-,11-,14?/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	1.10E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Gilead Sciences, Inc. Curated by ChEMBL					Assay Description Binding affinity to recombinant human ENT1 expressed in Saccharomyces cerevisiae assessed as inhibition of [3H]-uridine transport after 15 mins by sc...				Drug Metab Dispos 41: 916-22 (2013) Article DOI: 10.1124/dmd.112.049858 BindingDB Entry DOI: 10.7270/Q21N82VJ
					More data for this Ligand-Target Pair
Equilibrative nucleoside transporter 1 (Homo sapiens (Human))	BDBM14487 ((2R,3R,4S,5R)-2-(6-amino-9H-purin-9-yl)-5-(hydroxy...) Show SMILES Nc1ncnc2n(cnc12)[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1O Show InChI InChI=1S/C10H13N5O4/c11-8-5-9(13-2-12-8)15(3-14-5)10-7(18)6(17)4(1-16)19-10/h2-4,6-7,10,16-18H,1H2,(H2,11,12,13)/t4-,6-,7-,10-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Similars	Article PubMed	1.20E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Gilead Sciences, Inc. Curated by ChEMBL					Assay Description Binding affinity to recombinant human ENT1 expressed in Saccharomyces cerevisiae assessed as inhibition of [3H]-uridine transport after 15 mins by sc...				Drug Metab Dispos 41: 916-22 (2013) Article DOI: 10.1124/dmd.112.049858 BindingDB Entry DOI: 10.7270/Q21N82VJ
					More data for this Ligand-Target Pair
Polyphenol oxidase 2 (Agaricus bisporus (Common mushroom))	BDBM50326469 (3,4'-Dihydroxy-3',5'-dimethoxybiphenyl-4-carboxyli...) Show SMILES COc1cc(cc(OC)c1O)-c1ccc(C(O)=O)c(O)c1 Show InChI InChI=1S/C15H14O6/c1-20-12-6-9(7-13(21-2)14(12)17)8-3-4-10(15(18)19)11(16)5-8/h3-7,16-17H,1-2H3,(H,18,19)	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.50E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Jinan University Curated by ChEMBL					Assay Description Competitive inhibition of mushroom tyrosinase after 30 mins by Lineweaver-Burk double reciprocal plot analysis				Bioorg Med Chem 18: 6708-14 (2010) Article DOI: 10.1016/j.bmc.2010.07.062 BindingDB Entry DOI: 10.7270/Q2JS9QN4
					More data for this Ligand-Target Pair
Sodium/nucleoside cotransporter 2 (Homo sapiens (Human))	BDBM50088517 (CHEBI:16704 | Uridine) Show SMILES OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1ccc(=O)[nH]c1=O |r| Show InChI InChI=1S/C9H12N2O6/c12-3-4-6(14)7(15)8(17-4)11-2-1-5(13)10-9(11)16/h1-2,4,6-8,12,14-15H,3H2,(H,10,13,16)/t4-,6-,7-,8-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	3.10E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Gilead Sciences, Inc. Curated by ChEMBL					Assay Description Binding affinity to recombinant human CNT2 expressed in Saccharomyces cerevisiae assessed as inhibition of [3H]-uridine transport after 15 mins by sc...				Drug Metab Dispos 41: 916-22 (2013) Article DOI: 10.1124/dmd.112.049858 BindingDB Entry DOI: 10.7270/Q21N82VJ
					More data for this Ligand-Target Pair
Polyphenol oxidase 2 (Agaricus bisporus (Common mushroom))	BDBM50326455 (CHEMBL1243344 | N-Butyl-4'-hydroxy-3',5'-dimethoxy...) Show SMILES CCCCNC(=O)c1ccc(cc1)-c1cc(OC)c(O)c(OC)c1 Show InChI InChI=1S/C19H23NO4/c1-4-5-10-20-19(22)14-8-6-13(7-9-14)15-11-16(23-2)18(21)17(12-15)24-3/h6-9,11-12,21H,4-5,10H2,1-3H3,(H,20,22)	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.10E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Jinan University Curated by ChEMBL					Assay Description Competitive inhibition of mushroom tyrosinase after 30 mins by Lineweaver-Burk double reciprocal plot analysis				Bioorg Med Chem 18: 6708-14 (2010) Article DOI: 10.1016/j.bmc.2010.07.062 BindingDB Entry DOI: 10.7270/Q2JS9QN4
					More data for this Ligand-Target Pair
Sodium/nucleoside cotransporter 1 (Homo sapiens (Human))	BDBM50138530 ((2R,3R,5R)-2-Hydroxymethyl-5-{6-[(R)-(tetrahydro-f...) Show SMILES OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2c(N[C@@H]3CCOC3)ncnc12 Show InChI InChI=1S/C14H19N5O5/c20-3-8-10(21)11(22)14(24-8)19-6-17-9-12(15-5-16-13(9)19)18-7-1-2-23-4-7/h5-8,10-11,14,20-22H,1-4H2,(H,15,16,18)/t7?,8-,10-,11-,14?/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	3.70E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Gilead Sciences, Inc. Curated by ChEMBL					Assay Description Binding affinity to recombinant human CNT1 expressed in Saccharomyces cerevisiae assessed as inhibition of [3H]-uridine transport after 15 mins by sc...				Drug Metab Dispos 41: 916-22 (2013) Article DOI: 10.1124/dmd.112.049858 BindingDB Entry DOI: 10.7270/Q21N82VJ
					More data for this Ligand-Target Pair
Polyphenol oxidase 2 (Agaricus bisporus (Common mushroom))	BDBM50326456 (4'-Hydroxy-3',5'-dimethoxybiphenyl-4-carboxylic ac...) Show SMILES COc1cc(cc(OC)c1O)-c1ccc(cc1)C(O)=O Show InChI InChI=1S/C15H14O5/c1-19-12-7-11(8-13(20-2)14(12)16)9-3-5-10(6-4-9)15(17)18/h3-8,16H,1-2H3,(H,17,18)	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.80E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Jinan University Curated by ChEMBL					Assay Description Competitive inhibition of mushroom tyrosinase after 30 mins by Lineweaver-Burk double reciprocal plot analysis				Bioorg Med Chem 18: 6708-14 (2010) Article DOI: 10.1016/j.bmc.2010.07.062 BindingDB Entry DOI: 10.7270/Q2JS9QN4
					More data for this Ligand-Target Pair
Equilibrative nucleoside transporter 1 (Homo sapiens (Human))	BDBM50088517 (CHEBI:16704 | Uridine) Show SMILES OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1ccc(=O)[nH]c1=O |r| Show InChI InChI=1S/C9H12N2O6/c12-3-4-6(14)7(15)8(17-4)11-2-1-5(13)10-9(11)16/h1-2,4,6-8,12,14-15H,3H2,(H,10,13,16)/t4-,6-,7-,8-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	5.10E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Gilead Sciences, Inc. Curated by ChEMBL					Assay Description Binding affinity to recombinant human ENT1 expressed in Saccharomyces cerevisiae assessed as inhibition of [3H]-uridine transport after 15 mins by sc...				Drug Metab Dispos 41: 916-22 (2013) Article DOI: 10.1124/dmd.112.049858 BindingDB Entry DOI: 10.7270/Q21N82VJ
					More data for this Ligand-Target Pair
Polyphenol oxidase 2 (Agaricus bisporus (Common mushroom))	BDBM50326467 (CHEMBL1243315 | N-Benzyl-3,4'-dihydroxy-3',5'-dime...) Show SMILES COc1cc(cc(OC)c1O)-c1ccc(C(=O)NCc2ccccc2)c(O)c1 Show InChI InChI=1S/C22H21NO5/c1-27-19-11-16(12-20(28-2)21(19)25)15-8-9-17(18(24)10-15)22(26)23-13-14-6-4-3-5-7-14/h3-12,24-25H,13H2,1-2H3,(H,23,26)	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	6.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Jinan University Curated by ChEMBL					Assay Description Competitive inhibition of mushroom tyrosinase after 30 mins by Lineweaver-Burk double reciprocal plot analysis				Bioorg Med Chem 18: 6708-14 (2010) Article DOI: 10.1016/j.bmc.2010.07.062 BindingDB Entry DOI: 10.7270/Q2JS9QN4
					More data for this Ligand-Target Pair
Equilibrative nucleoside transporter 2 (Homo sapiens (Human))	BDBM14487 ((2R,3R,4S,5R)-2-(6-amino-9H-purin-9-yl)-5-(hydroxy...) Show SMILES Nc1ncnc2n(cnc12)[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1O Show InChI InChI=1S/C10H13N5O4/c11-8-5-9(13-2-12-8)15(3-14-5)10-7(18)6(17)4(1-16)19-10/h2-4,6-7,10,16-18H,1H2,(H2,11,12,13)/t4-,6-,7-,10-/m1/s1	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Similars	Article PubMed	1.06E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Gilead Sciences, Inc. Curated by ChEMBL					Assay Description Binding affinity to recombinant human ENT2 expressed in Saccharomyces cerevisiae assessed as inhibition of [3H]-uridine transport after 15 mins by sc...				Drug Metab Dispos 41: 916-22 (2013) Article DOI: 10.1124/dmd.112.049858 BindingDB Entry DOI: 10.7270/Q21N82VJ
					More data for this Ligand-Target Pair
Solute carrier family 28 member 3 (Homo sapiens (Human))	BDBM50138530 ((2R,3R,5R)-2-Hydroxymethyl-5-{6-[(R)-(tetrahydro-f...) Show SMILES OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2c(N[C@@H]3CCOC3)ncnc12 Show InChI InChI=1S/C14H19N5O5/c20-3-8-10(21)11(22)14(24-8)19-6-17-9-12(15-5-16-13(9)19)18-7-1-2-23-4-7/h5-8,10-11,14,20-22H,1-4H2,(H,15,16,18)/t7?,8-,10-,11-,14?/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	1.26E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Gilead Sciences, Inc. Curated by ChEMBL					Assay Description Binding affinity to recombinant human CNT3 expressed in Saccharomyces cerevisiae assessed as inhibition of [3H]-uridine transport after 5 mins by sci...				Drug Metab Dispos 41: 916-22 (2013) Article DOI: 10.1124/dmd.112.049858 BindingDB Entry DOI: 10.7270/Q21N82VJ
					More data for this Ligand-Target Pair
Equilibrative nucleoside transporter 2 (Homo sapiens (Human))	BDBM50138530 ((2R,3R,5R)-2-Hydroxymethyl-5-{6-[(R)-(tetrahydro-f...) Show SMILES OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2c(N[C@@H]3CCOC3)ncnc12 Show InChI InChI=1S/C14H19N5O5/c20-3-8-10(21)11(22)14(24-8)19-6-17-9-12(15-5-16-13(9)19)18-7-1-2-23-4-7/h5-8,10-11,14,20-22H,1-4H2,(H,15,16,18)/t7?,8-,10-,11-,14?/m1/s1	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	1.89E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Gilead Sciences, Inc. Curated by ChEMBL					Assay Description Binding affinity to recombinant human ENT2 expressed in Saccharomyces cerevisiae assessed as inhibition of [3H]-uridine transport after 15 mins by sc...				Drug Metab Dispos 41: 916-22 (2013) Article DOI: 10.1124/dmd.112.049858 BindingDB Entry DOI: 10.7270/Q21N82VJ
					More data for this Ligand-Target Pair
Sodium/nucleoside cotransporter 2 (Homo sapiens (Human))	BDBM50138530 ((2R,3R,5R)-2-Hydroxymethyl-5-{6-[(R)-(tetrahydro-f...) Show SMILES OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2c(N[C@@H]3CCOC3)ncnc12 Show InChI InChI=1S/C14H19N5O5/c20-3-8-10(21)11(22)14(24-8)19-6-17-9-12(15-5-16-13(9)19)18-7-1-2-23-4-7/h5-8,10-11,14,20-22H,1-4H2,(H,15,16,18)/t7?,8-,10-,11-,14?/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	2.31E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Gilead Sciences, Inc. Curated by ChEMBL					Assay Description Binding affinity to recombinant human CNT2 expressed in Saccharomyces cerevisiae assessed as inhibition of [3H]-uridine transport after 15 mins by sc...				Drug Metab Dispos 41: 916-22 (2013) Article DOI: 10.1124/dmd.112.049858 BindingDB Entry DOI: 10.7270/Q21N82VJ
					More data for this Ligand-Target Pair
Equilibrative nucleoside transporter 2 (Homo sapiens (Human))	BDBM50088517 (CHEBI:16704 | Uridine) Show SMILES OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1ccc(=O)[nH]c1=O |r| Show InChI InChI=1S/C9H12N2O6/c12-3-4-6(14)7(15)8(17-4)11-2-1-5(13)10-9(11)16/h1-2,4,6-8,12,14-15H,3H2,(H,10,13,16)/t4-,6-,7-,8-/m1/s1	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	2.42E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Gilead Sciences, Inc. Curated by ChEMBL					Assay Description Binding affinity to recombinant human ENT2 expressed in Saccharomyces cerevisiae assessed as inhibition of [3H]-uridine transport after 15 mins by sc...				Drug Metab Dispos 41: 916-22 (2013) Article DOI: 10.1124/dmd.112.049858 BindingDB Entry DOI: 10.7270/Q21N82VJ
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50165469 (CHEMBL3797911) Show SMILES COc1ccc2c(OCc3nnc4ncc(nn34)-c3ccccc3)ccnc2c1 Show InChI InChI=1S/C21H16N6O2/c1-28-15-7-8-16-17(11-15)22-10-9-19(16)29-13-20-24-25-21-23-12-18(26-27(20)21)14-5-3-2-4-6-14/h2-12H,13H2,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.190	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences (CAS) Curated by ChEMBL					Assay Description Inhibition of recombinant c-Met (unknown origin) using poly (Glu, Tyr) 4:1 as substrate incubated for 60 mins by ELISA				Eur J Med Chem 116: 239-251 (2016) Article DOI: 10.1016/j.ejmech.2016.03.076 BindingDB Entry DOI: 10.7270/Q2P27111
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50165465 (CHEMBL3797579) Show SMILES Fc1ccc(cc1)-c1cnc2nnc(n2n1)C(F)(F)c1ccc2ncccc2c1 Show InChI InChI=1S/C20H11F3N6/c21-15-6-3-12(4-7-15)17-11-25-19-27-26-18(29(19)28-17)20(22,23)14-5-8-16-13(10-14)2-1-9-24-16/h1-11H	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	0.240	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences (CAS) Curated by ChEMBL					Assay Description Inhibition of recombinant c-Met (unknown origin) using poly (Glu, Tyr) 4:1 as substrate incubated for 60 mins by ELISA				Eur J Med Chem 116: 239-251 (2016) Article DOI: 10.1016/j.ejmech.2016.03.076 BindingDB Entry DOI: 10.7270/Q2P27111
					More data for this Ligand-Target Pair				3D Structure (crystal)
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50165571 (CHEMBL3800471) Show SMILES Oc1cccc(c1)-c1cnc2nnc(Cc3ccc4ncccc4c3)n2n1 Show InChI InChI=1S/C20H14N6O/c27-16-5-1-3-15(11-16)18-12-22-20-24-23-19(26(20)25-18)10-13-6-7-17-14(9-13)4-2-8-21-17/h1-9,11-12,27H,10H2	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.420	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences (CAS) Curated by ChEMBL					Assay Description Inhibition of recombinant c-Met (unknown origin) using poly (Glu, Tyr) 4:1 as substrate incubated for 60 mins by ELISA				Eur J Med Chem 116: 239-251 (2016) Article DOI: 10.1016/j.ejmech.2016.03.076 BindingDB Entry DOI: 10.7270/Q2P27111
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50165466 (CHEMBL3800420) Show SMILES Cn1cc(cn1)-c1cnc2nnc(n2n1)C(F)(F)c1ccc2ncccc2c1 Show InChI InChI=1S/C18H12F2N8/c1-27-10-12(8-23-27)15-9-22-17-25-24-16(28(17)26-15)18(19,20)13-4-5-14-11(7-13)3-2-6-21-14/h2-10H,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.430	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences (CAS) Curated by ChEMBL					Assay Description Inhibition of c-Met in human EBC-1 cells assessed as reduction in cell proliferation after 72 hrs by SRB or MTT assay				Eur J Med Chem 116: 239-251 (2016) Article DOI: 10.1016/j.ejmech.2016.03.076 BindingDB Entry DOI: 10.7270/Q2P27111
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50165465 (CHEMBL3797579) Show SMILES Fc1ccc(cc1)-c1cnc2nnc(n2n1)C(F)(F)c1ccc2ncccc2c1 Show InChI InChI=1S/C20H11F3N6/c21-15-6-3-12(4-7-15)17-11-25-19-27-26-18(29(19)28-17)20(22,23)14-5-8-16-13(10-14)2-1-9-24-16/h1-11H	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	0.460	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences (CAS) Curated by ChEMBL					Assay Description Inhibition of c-Met in human MKN45 cells assessed as reduction in cell proliferation after 72 hrs by SRB or MTT assay				Eur J Med Chem 116: 239-251 (2016) Article DOI: 10.1016/j.ejmech.2016.03.076 BindingDB Entry DOI: 10.7270/Q2P27111
					More data for this Ligand-Target Pair				3D Structure (crystal)
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50165567 (CHEMBL3797914) Show SMILES Cn1cc(cn1)-c1cnc2nnc(Cc3ccc4ncccc4c3)n2n1 Show InChI InChI=1S/C18H14N8/c1-25-11-14(9-21-25)16-10-20-18-23-22-17(26(18)24-16)8-12-4-5-15-13(7-12)3-2-6-19-15/h2-7,9-11H,8H2,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.460	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences (CAS) Curated by ChEMBL					Assay Description Inhibition of recombinant c-Met (unknown origin) using poly (Glu, Tyr) 4:1 as substrate incubated for 60 mins by ELISA				Eur J Med Chem 116: 239-251 (2016) Article DOI: 10.1016/j.ejmech.2016.03.076 BindingDB Entry DOI: 10.7270/Q2P27111
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50165578 (CHEMBL3799192) Show SMILES C(c1nnc2ncc(nn12)-c1ccccc1)c1ccc2ncccc2c1 Show InChI InChI=1S/C20H14N6/c1-2-5-15(6-3-1)18-13-22-20-24-23-19(26(20)25-18)12-14-8-9-17-16(11-14)7-4-10-21-17/h1-11,13H,12H2	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.490	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences (CAS) Curated by ChEMBL					Assay Description Inhibition of recombinant c-Met (unknown origin) using poly (Glu, Tyr) 4:1 as substrate incubated for 60 mins by ELISA				Eur J Med Chem 116: 239-251 (2016) Article DOI: 10.1016/j.ejmech.2016.03.076 BindingDB Entry DOI: 10.7270/Q2P27111
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50165467 (CHEMBL3798905) Show SMILES FC(F)(c1nnc2ncc(nn12)-c1ccco1)c1ccc2ncccc2c1 Show InChI InChI=1S/C18H10F2N6O/c19-18(20,12-5-6-13-11(9-12)3-1-7-21-13)16-23-24-17-22-10-14(25-26(16)17)15-4-2-8-27-15/h1-10H	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.5	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences (CAS) Curated by ChEMBL					Assay Description Inhibition of recombinant c-Met (unknown origin) using poly (Glu, Tyr) 4:1 as substrate incubated for 60 mins by ELISA				Eur J Med Chem 116: 239-251 (2016) Article DOI: 10.1016/j.ejmech.2016.03.076 BindingDB Entry DOI: 10.7270/Q2P27111
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50165466 (CHEMBL3800420) Show SMILES Cn1cc(cn1)-c1cnc2nnc(n2n1)C(F)(F)c1ccc2ncccc2c1 Show InChI InChI=1S/C18H12F2N8/c1-27-10-12(8-23-27)15-9-22-17-25-24-16(28(17)26-15)18(19,20)13-4-5-14-11(7-13)3-2-6-21-14/h2-10H,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.5	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences (CAS) Curated by ChEMBL					Assay Description Inhibition of recombinant c-Met (unknown origin) using poly (Glu, Tyr) 4:1 as substrate incubated for 60 mins by ELISA				Eur J Med Chem 116: 239-251 (2016) Article DOI: 10.1016/j.ejmech.2016.03.076 BindingDB Entry DOI: 10.7270/Q2P27111
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50165572 (CHEMBL3800559) Show SMILES COc1cccc(c1)-c1cnc2nnc(Cc3ccc4ncccc4c3)n2n1 Show InChI InChI=1S/C21H16N6O/c1-28-17-6-2-4-16(12-17)19-13-23-21-25-24-20(27(21)26-19)11-14-7-8-18-15(10-14)5-3-9-22-18/h2-10,12-13H,11H2,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.590	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences (CAS) Curated by ChEMBL					Assay Description Inhibition of recombinant c-Met (unknown origin) using poly (Glu, Tyr) 4:1 as substrate incubated for 60 mins by ELISA				Eur J Med Chem 116: 239-251 (2016) Article DOI: 10.1016/j.ejmech.2016.03.076 BindingDB Entry DOI: 10.7270/Q2P27111
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50165468 (CHEMBL3799263) Show SMILES CCCn1cc(cn1)-c1cnc2nnc(n2n1)C(F)(F)c1ccc2ncccc2c1 Show InChI InChI=1S/C20H16F2N8/c1-2-8-29-12-14(10-25-29)17-11-24-19-27-26-18(30(19)28-17)20(21,22)15-5-6-16-13(9-15)4-3-7-23-16/h3-7,9-12H,2,8H2,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.670	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences (CAS) Curated by ChEMBL					Assay Description Inhibition of c-Met in human EBC-1 cells assessed as reduction in cell proliferation after 72 hrs by SRB or MTT assay				Eur J Med Chem 116: 239-251 (2016) Article DOI: 10.1016/j.ejmech.2016.03.076 BindingDB Entry DOI: 10.7270/Q2P27111
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50165465 (CHEMBL3797579) Show SMILES Fc1ccc(cc1)-c1cnc2nnc(n2n1)C(F)(F)c1ccc2ncccc2c1 Show InChI InChI=1S/C20H11F3N6/c21-15-6-3-12(4-7-15)17-11-25-19-27-26-18(29(19)28-17)20(22,23)14-5-8-16-13(10-14)2-1-9-24-16/h1-11H	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	0.850	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences (CAS) Curated by ChEMBL					Assay Description Inhibition of c-Met in human EBC-1 cells assessed as reduction in cell proliferation after 72 hrs by SRB or MTT assay				Eur J Med Chem 116: 239-251 (2016) Article DOI: 10.1016/j.ejmech.2016.03.076 BindingDB Entry DOI: 10.7270/Q2P27111
					More data for this Ligand-Target Pair				3D Structure (crystal)
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50165468 (CHEMBL3799263) Show SMILES CCCn1cc(cn1)-c1cnc2nnc(n2n1)C(F)(F)c1ccc2ncccc2c1 Show InChI InChI=1S/C20H16F2N8/c1-2-8-29-12-14(10-25-29)17-11-24-19-27-26-18(30(19)28-17)20(21,22)15-5-6-16-13(9-15)4-3-7-23-16/h3-7,9-12H,2,8H2,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.900	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences (CAS) Curated by ChEMBL					Assay Description Inhibition of recombinant c-Met (unknown origin) using poly (Glu, Tyr) 4:1 as substrate incubated for 60 mins by ELISA				Eur J Med Chem 116: 239-251 (2016) Article DOI: 10.1016/j.ejmech.2016.03.076 BindingDB Entry DOI: 10.7270/Q2P27111
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM163243 (US9062045, Comparator No. 1 (JNJ-38877605)) Show SMILES Cn1cc(cn1)-c1ccc2nnc(n2n1)C(F)(F)c1ccc2ncccc2c1 Show InChI InChI=1S/C19H13F2N7/c1-27-11-13(10-23-27)16-6-7-17-24-25-18(28(17)26-16)19(20,21)14-4-5-15-12(9-14)3-2-8-22-15/h2-11H,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.950	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences (CAS) Curated by ChEMBL					Assay Description Inhibition of recombinant c-Met (unknown origin) using poly (Glu, Tyr) 4:1 as substrate incubated for 60 mins by ELISA				Eur J Med Chem 116: 239-251 (2016) Article DOI: 10.1016/j.ejmech.2016.03.076 BindingDB Entry DOI: 10.7270/Q2P27111
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 3 (Homo sapiens (Human))	BDBM50549813 (CHEMBL4776177) Show SMILES CC(C)c1cc(Nc2cc(nc(\C=C\c3ccc(NC(=O)C=C)cc3)n2)N2CCN(C)CC2)n[nH]1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of His-tagged FGFR3 V555M mutant (unknown origin) expressed in insect cells using poly Glu-Tyr preincubated for 1 hr followed by substrate...				Citation and Details Article DOI: 10.1021/acsmedchemlett.0c00517 BindingDB Entry DOI: 10.7270/Q2RV0S9M
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50165565 (CHEMBL3800295) Show SMILES CCCn1cc(cn1)-c1cnc2nnc(Cc3ccc4ncccc4c3)n2n1 Show InChI InChI=1S/C20H18N8/c1-2-8-27-13-16(11-23-27)18-12-22-20-25-24-19(28(20)26-18)10-14-5-6-17-15(9-14)4-3-7-21-17/h3-7,9,11-13H,2,8,10H2,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.20	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences (CAS) Curated by ChEMBL					Assay Description Inhibition of recombinant c-Met (unknown origin) using poly (Glu, Tyr) 4:1 as substrate incubated for 60 mins by ELISA				Eur J Med Chem 116: 239-251 (2016) Article DOI: 10.1016/j.ejmech.2016.03.076 BindingDB Entry DOI: 10.7270/Q2P27111
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50165576 (CHEMBL3800427) Show SMILES Clc1ccc(cc1Cl)-c1cnc2nnc(Cc3ccc4ncccc4c3)n2n1 Show InChI InChI=1S/C20H12Cl2N6/c21-15-5-4-14(10-16(15)22)18-11-24-20-26-25-19(28(20)27-18)9-12-3-6-17-13(8-12)2-1-7-23-17/h1-8,10-11H,9H2	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.20	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences (CAS) Curated by ChEMBL					Assay Description Inhibition of recombinant c-Met (unknown origin) using poly (Glu, Tyr) 4:1 as substrate incubated for 60 mins by ELISA				Eur J Med Chem 116: 239-251 (2016) Article DOI: 10.1016/j.ejmech.2016.03.076 BindingDB Entry DOI: 10.7270/Q2P27111
					More data for this Ligand-Target Pair
Nucleoprotein TPR (Mus musculus)	BDBM50165465 (CHEMBL3797579) Show SMILES Fc1ccc(cc1)-c1cnc2nnc(n2n1)C(F)(F)c1ccc2ncccc2c1 Show InChI InChI=1S/C20H11F3N6/c21-15-6-3-12(4-7-15)17-11-25-19-27-26-18(29(19)28-17)20(22,23)14-5-8-16-13(10-14)2-1-9-24-16/h1-11H	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	1.30	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences (CAS) Curated by ChEMBL					Assay Description Inhibition of TPR-MET in mouse BAF3 cells assessed as reduction in cell proliferation after 72 hrs by SRB or MTT assay				Eur J Med Chem 116: 239-251 (2016) Article DOI: 10.1016/j.ejmech.2016.03.076 BindingDB Entry DOI: 10.7270/Q2P27111
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50165470 (CHEMBL3797871) Show SMILES FC(F)(c1nnc2ncc(nn12)-c1cccs1)c1ccc2ncccc2c1 Show InChI InChI=1S/C18H10F2N6S/c19-18(20,12-5-6-13-11(9-12)3-1-7-21-13)16-23-24-17-22-10-14(25-26(16)17)15-4-2-8-27-15/h1-10H	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.40	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences (CAS) Curated by ChEMBL					Assay Description Inhibition of recombinant c-Met (unknown origin) using poly (Glu, Tyr) 4:1 as substrate incubated for 60 mins by ELISA				Eur J Med Chem 116: 239-251 (2016) Article DOI: 10.1016/j.ejmech.2016.03.076 BindingDB Entry DOI: 10.7270/Q2P27111
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50165575 (CHEMBL3798623) Show SMILES [O-][N+](=O)c1cccc(c1)-c1cnc2nnc(Cc3ccc4ncccc4c3)n2n1 Show InChI InChI=1S/C20H13N7O2/c28-27(29)16-5-1-3-15(11-16)18-12-22-20-24-23-19(26(20)25-18)10-13-6-7-17-14(9-13)4-2-8-21-17/h1-9,11-12H,10H2	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences (CAS) Curated by ChEMBL					Assay Description Inhibition of recombinant c-Met (unknown origin) using poly (Glu, Tyr) 4:1 as substrate incubated for 60 mins by ELISA				Eur J Med Chem 116: 239-251 (2016) Article DOI: 10.1016/j.ejmech.2016.03.076 BindingDB Entry DOI: 10.7270/Q2P27111
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50165569 (CHEMBL3797547) Show SMILES C(c1nnc2ncc(nn12)-c1cccs1)c1ccc2ncccc2c1 Show InChI InChI=1S/C18H12N6S/c1-3-13-9-12(5-6-14(13)19-7-1)10-17-21-22-18-20-11-15(23-24(17)18)16-4-2-8-25-16/h1-9,11H,10H2	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.30	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences (CAS) Curated by ChEMBL					Assay Description Inhibition of recombinant c-Met (unknown origin) using poly (Glu, Tyr) 4:1 as substrate incubated for 60 mins by ELISA				Eur J Med Chem 116: 239-251 (2016) Article DOI: 10.1016/j.ejmech.2016.03.076 BindingDB Entry DOI: 10.7270/Q2P27111
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50165570 (CHEMBL3798174) Show SMILES C(c1nnc2ncc(nn12)-c1cnc2ccccc2c1)c1ccc2ncccc2c1 Show InChI InChI=1S/C23H15N7/c1-2-6-19-17(4-1)12-18(13-25-19)21-14-26-23-28-27-22(30(23)29-21)11-15-7-8-20-16(10-15)5-3-9-24-20/h1-10,12-14H,11H2	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.30	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences (CAS) Curated by ChEMBL					Assay Description Inhibition of recombinant c-Met (unknown origin) using poly (Glu, Tyr) 4:1 as substrate incubated for 60 mins by ELISA				Eur J Med Chem 116: 239-251 (2016) Article DOI: 10.1016/j.ejmech.2016.03.076 BindingDB Entry DOI: 10.7270/Q2P27111
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50165467 (CHEMBL3798905) Show SMILES FC(F)(c1nnc2ncc(nn12)-c1ccco1)c1ccc2ncccc2c1 Show InChI InChI=1S/C18H10F2N6O/c19-18(20,12-5-6-13-11(9-12)3-1-7-21-13)16-23-24-17-22-10-14(25-26(16)17)15-4-2-8-27-15/h1-10H	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.30	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences (CAS) Curated by ChEMBL					Assay Description Inhibition of c-Met in human EBC-1 cells assessed as reduction in cell proliferation after 72 hrs by SRB or MTT assay				Eur J Med Chem 116: 239-251 (2016) Article DOI: 10.1016/j.ejmech.2016.03.076 BindingDB Entry DOI: 10.7270/Q2P27111
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50165574 (CHEMBL3797307) Show SMILES Clc1ccc(cc1)-c1cnc2nnc(Cc3ccc4ncccc4c3)n2n1 Show InChI InChI=1S/C20H13ClN6/c21-16-6-4-14(5-7-16)18-12-23-20-25-24-19(27(20)26-18)11-13-3-8-17-15(10-13)2-1-9-22-17/h1-10,12H,11H2	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.5	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences (CAS) Curated by ChEMBL					Assay Description Inhibition of recombinant c-Met (unknown origin) using poly (Glu, Tyr) 4:1 as substrate incubated for 60 mins by ELISA				Eur J Med Chem 116: 239-251 (2016) Article DOI: 10.1016/j.ejmech.2016.03.076 BindingDB Entry DOI: 10.7270/Q2P27111
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50165476 (CHEMBL3800061) Show SMILES FC(F)(c1nnc2ncc(nn12)-c1ccccc1)c1ccc2ncccc2c1 Show InChI InChI=1S/C20H12F2N6/c21-20(22,15-8-9-16-14(11-15)7-4-10-23-16)18-25-26-19-24-12-17(27-28(18)19)13-5-2-1-3-6-13/h1-12H	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.80	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences (CAS) Curated by ChEMBL					Assay Description Inhibition of recombinant c-Met (unknown origin) using poly (Glu, Tyr) 4:1 as substrate incubated for 60 mins by ELISA				Eur J Med Chem 116: 239-251 (2016) Article DOI: 10.1016/j.ejmech.2016.03.076 BindingDB Entry DOI: 10.7270/Q2P27111
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50165568 (CHEMBL3798660) Show SMILES C(c1nnc2ncc(nn12)-c1cnn(Cc2ccccc2)c1)c1ccc2ncccc2c1 Show InChI InChI=1S/C24H18N8/c1-2-5-17(6-3-1)15-31-16-20(13-27-31)22-14-26-24-29-28-23(32(24)30-22)12-18-8-9-21-19(11-18)7-4-10-25-21/h1-11,13-14,16H,12,15H2	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	3.20	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences (CAS) Curated by ChEMBL					Assay Description Inhibition of recombinant c-Met (unknown origin) using poly (Glu, Tyr) 4:1 as substrate incubated for 60 mins by ELISA				Eur J Med Chem 116: 239-251 (2016) Article DOI: 10.1016/j.ejmech.2016.03.076 BindingDB Entry DOI: 10.7270/Q2P27111
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50165566 (CHEMBL3799924) Show SMILES CCn1cc(cn1)-c1cnc2nnc(Cc3ccc4ncccc4c3)n2n1 Show InChI InChI=1S/C19H16N8/c1-2-26-12-15(10-22-26)17-11-21-19-24-23-18(27(19)25-17)9-13-5-6-16-14(8-13)4-3-7-20-16/h3-8,10-12H,2,9H2,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.10	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences (CAS) Curated by ChEMBL					Assay Description Inhibition of recombinant c-Met (unknown origin) using poly (Glu, Tyr) 4:1 as substrate incubated for 60 mins by ELISA				Eur J Med Chem 116: 239-251 (2016) Article DOI: 10.1016/j.ejmech.2016.03.076 BindingDB Entry DOI: 10.7270/Q2P27111
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50165573 (CHEMBL3798130) Show SMILES Brc1ccc(cc1)-c1cnc2nnc(Cc3ccc4ncccc4c3)n2n1 Show InChI InChI=1S/C20H13BrN6/c21-16-6-4-14(5-7-16)18-12-23-20-25-24-19(27(20)26-18)11-13-3-8-17-15(10-13)2-1-9-22-17/h1-10,12H,11H2	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.20	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences (CAS) Curated by ChEMBL					Assay Description Inhibition of recombinant c-Met (unknown origin) using poly (Glu, Tyr) 4:1 as substrate incubated for 60 mins by ELISA				Eur J Med Chem 116: 239-251 (2016) Article DOI: 10.1016/j.ejmech.2016.03.076 BindingDB Entry DOI: 10.7270/Q2P27111
					More data for this Ligand-Target Pair

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