BindingDB PrimarySearch

Found 455 hits with Last Name = 'zaib' and Initial = 's'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Amine oxidase [flavin-containing] A (Homo sapiens (Human))	BDBM218829 (1,4-Bis(2-pentanoylimino-5-(2-methoxy-2-oxoethylid...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1	n/a	n/a	n/a	n/a	7.4	n/a
Quaid-i-Azam University					Assay Description The assay was performed in a polystyrene 96-well plate having flat bottom containing 200 μL of the total reaction mixture. For each assay, mixtu...				Bioorg Chem 70: 17-26 (2017) Article DOI: 10.1016/j.bioorg.2016.11.004 BindingDB Entry DOI: 10.7270/Q2WM1C7Z
Quaid-i-Azam University					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] A (Homo sapiens (Human))	BDBM15581 (CHEMBL8706 \| CLG \| CLORGILINE \| Clorgyline \| N-[3-...) Show SMILES CN(CCCOc1ccc(Cl)cc1Cl)CC#C Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	4.5	n/a	n/a	n/a	n/a	7.4	n/a
Quaid-i-Azam University					Assay Description The assay was performed in a polystyrene 96-well plate having flat bottom containing 200 μL of the total reaction mixture. For each assay, mixtu...				Bioorg Chem 70: 17-26 (2017) Article DOI: 10.1016/j.bioorg.2016.11.004 BindingDB Entry DOI: 10.7270/Q2WM1C7Z
Quaid-i-Azam University					More data for this Ligand-Target Pair				3D Structure (crystal)
Amine oxidase [flavin-containing] A (Rattus norvegicus (rat))	BDBM15581 (CHEMBL8706 \| CLG \| CLORGILINE \| Clorgyline \| N-[3-...) Show SMILES CN(CCCOc1ccc(Cl)cc1Cl)CC#C Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars	DrugBank PDB Article PubMed	n/a	n/a	4.5	n/a	n/a	n/a	n/a	n/a	n/a
Government College University Curated by ChEMBL					Assay Description Inhibition of MAO-A in rat liver mitochondria using p-tyramine as substrate preincubated for 10 mins followed by substrate addition measured after 30...				Eur J Med Chem 143: 1373-1386 (2018) Article DOI: 10.1016/j.ejmech.2017.10.036 BindingDB Entry DOI: 10.7270/Q21V5HHC
Government College University Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Amine oxidase [flavin-containing] A (Homo sapiens (Human))	BDBM218826 (1,2-Bis(2-(2-chlorobenzoylimino)-5-(2-methoxy-2-ox...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	9	n/a	n/a	n/a	n/a	7.4	n/a
Quaid-i-Azam University					Assay Description The assay was performed in a polystyrene 96-well plate having flat bottom containing 200 μL of the total reaction mixture. For each assay, mixtu...				Bioorg Chem 70: 17-26 (2017) Article DOI: 10.1016/j.bioorg.2016.11.004 BindingDB Entry DOI: 10.7270/Q2WM1C7Z
Quaid-i-Azam University					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Bos taurus)	BDBM50004262 (CHEMBL1438301) Show SMILES NS(=O)(=O)c1ccc(NC(=S)NC(=O)c2cccs2)cc1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
COMSATS Institute of Information Technology Curated by ChEMBL					Assay Description Inhibition of bovine erythrocyte carbonic anhydrase 2 using p-nitrophenyl acetate as substrate preincubated for 10 mins before substrate addition mea...				Eur J Med Chem 78: 140-50 (2014) Article DOI: 10.1016/j.ejmech.2014.03.023 BindingDB Entry DOI: 10.7270/Q2PN975X
					More data for this Ligand-Target Pair
Cholinesterase (Equus caballus (Horse))	BDBM50004244 (CHEMBL3237461) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	17	n/a	n/a	n/a	n/a	n/a	n/a
Government College Women University Curated by ChEMBL					Assay Description Inhibition of BuChE in equine serum using butyrylthiocholine chloride as substrate preincubated with enzyme for 10 mins prior to substrate challenge ...				Eur J Med Chem 78: 106-17 (2014) Article DOI: 10.1016/j.ejmech.2014.03.035 BindingDB Entry DOI: 10.7270/Q2TD9ZVD
Government College Women University Curated by ChEMBL					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] B (Homo sapiens (Human))	BDBM39862 (Deprenyl \| METHYL-(1-METHYL-2-PHENYL-ETHYL)-PROP-2...) Show SMILES CC(Cc1ccccc1)N(C)CC#C Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase DrugBank MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	19.6	n/a	n/a	n/a	n/a	7.4	n/a
Quaid-i-Azam University					Assay Description The assay was performed in a polystyrene 96-well plate having flat bottom containing 200 μL of the total reaction mixture. For each assay, mixtu...				Bioorg Chem 70: 17-26 (2017) Article DOI: 10.1016/j.bioorg.2016.11.004 BindingDB Entry DOI: 10.7270/Q2WM1C7Z
Quaid-i-Azam University					More data for this Ligand-Target Pair
Cholinesterase (Homo sapiens (Human))	BDBM8960 ((+/-)-2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimet...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
Quaid-i-Azam University Curated by ChEMBL					Assay Description Inhibition of human BChE by Ellman's method				Bioorg Med Chem 22: 6163-73 (2014) Article DOI: 10.1016/j.bmc.2014.08.026 BindingDB Entry DOI: 10.7270/Q2JQ12M3
Quaid-i-Azam University Curated by ChEMBL					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] B (Rattus norvegicus (rat))	BDBM39862 (Deprenyl \| METHYL-(1-METHYL-2-PHENYL-ETHYL)-PROP-2...) Show SMILES CC(Cc1ccccc1)N(C)CC#C Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase DrugBank MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
Government College University Curated by ChEMBL					Assay Description Inhibition of MAO-B in rat liver mitochondria using p-tyramine as substrate preincubated for 10 mins followed by substrate addition measured after 30...				Eur J Med Chem 143: 1373-1386 (2018) Article DOI: 10.1016/j.ejmech.2017.10.036 BindingDB Entry DOI: 10.7270/Q21V5HHC
Government College University Curated by ChEMBL					More data for this Ligand-Target Pair
Cholinesterase (Equus caballus (Horse))	BDBM50004238 (CHEMBL3237453) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	26	n/a	n/a	n/a	n/a	n/a	n/a
Government College Women University Curated by ChEMBL					Assay Description Inhibition of BuChE in equine serum using butyrylthiocholine chloride as substrate preincubated with enzyme for 10 mins prior to substrate challenge ...				Eur J Med Chem 78: 106-17 (2014) Article DOI: 10.1016/j.ejmech.2014.03.035 BindingDB Entry DOI: 10.7270/Q2TD9ZVD
Government College Women University Curated by ChEMBL					More data for this Ligand-Target Pair
Acetylcholinesterase (Electrophorus electricus (Electric eel))	BDBM8960 ((+/-)-2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimet...) Show SMILES Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
Quaid-I-Azam University Curated by ChEMBL					Assay Description Inhibition of electric eel acetylcholinesterase using acetylthiocholine iodide as substrate preincubated for 10 mins before substrate addition after ...				Eur J Med Chem 78: 43-53 (2014) Article DOI: 10.1016/j.ejmech.2014.03.015 BindingDB Entry DOI: 10.7270/Q2KW5HKK
Quaid-I-Azam University Curated by ChEMBL					More data for this Ligand-Target Pair
Acetylcholinesterase (Electrophorus electricus (Electric eel))	BDBM8960 ((+/-)-2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimet...) Show SMILES Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
Quaid-I-Azam University					Assay Description Newly synthesized coumarin thioureas were tested against electric eel AChE and horse serum BChE. The cholinesterase inhibitory activity was measured ...				Bioorg Chem 63: 58-63 (2015) Article DOI: 10.1016/j.bioorg.2015.09.009 BindingDB Entry DOI: 10.7270/Q2W957Z4
Quaid-I-Azam University					More data for this Ligand-Target Pair
Acetylcholinesterase (Electrophorus electricus (Electric eel))	BDBM8960 ((+/-)-2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimet...) Show SMILES Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
Quaid-i-Azam University Curated by ChEMBL					Assay Description Inhibition of electric eel acetylcholinesterase using acetylthiocholine iodide as substrate preincubated for 10 mins before substrate addition after ...				Eur J Med Chem 78: 167-77 (2014) Article DOI: 10.1016/j.ejmech.2014.03.046 BindingDB Entry DOI: 10.7270/Q2F76F32
Quaid-i-Azam University Curated by ChEMBL					More data for this Ligand-Target Pair
Acetylcholinesterase (Electrophorus electricus (Electric eel))	BDBM173566 (1-(2-Oxo-2H-chromene-3-carbonyl)-3-(3-chlorophenyl...) Show SMILES Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
Quaid-I-Azam University					Assay Description Newly synthesized coumarin thioureas were tested against electric eel AChE and horse serum BChE. The cholinesterase inhibitory activity was measured ...				Bioorg Chem 63: 58-63 (2015) Article DOI: 10.1016/j.bioorg.2015.09.009 BindingDB Entry DOI: 10.7270/Q2W957Z4
Quaid-I-Azam University					More data for this Ligand-Target Pair
Cholinesterase (Equus caballus (Horse))	BDBM50004241 (CHEMBL3233057) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	41	n/a	n/a	n/a	n/a	n/a	n/a
Government College Women University Curated by ChEMBL					Assay Description Inhibition of BuChE in equine serum using butyrylthiocholine chloride as substrate preincubated with enzyme for 10 mins prior to substrate challenge ...				Eur J Med Chem 78: 106-17 (2014) Article DOI: 10.1016/j.ejmech.2014.03.035 BindingDB Entry DOI: 10.7270/Q2TD9ZVD
Government College Women University Curated by ChEMBL					More data for this Ligand-Target Pair
Cholinesterase (Equus caballus (Horse))	BDBM50004248 (CHEMBL3237466) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	43	n/a	n/a	n/a	n/a	n/a	n/a
Government College Women University Curated by ChEMBL					Assay Description Inhibition of BuChE in equine serum using butyrylthiocholine chloride as substrate preincubated with enzyme for 10 mins prior to substrate challenge ...				Eur J Med Chem 78: 106-17 (2014) Article DOI: 10.1016/j.ejmech.2014.03.035 BindingDB Entry DOI: 10.7270/Q2TD9ZVD
Government College Women University Curated by ChEMBL					More data for this Ligand-Target Pair
Cholinesterase (Equus caballus (Horse))	BDBM50004240 (CHEMBL3237456) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	43	n/a	n/a	n/a	n/a	n/a	n/a
Government College Women University Curated by ChEMBL					Assay Description Inhibition of BuChE in equine serum using butyrylthiocholine chloride as substrate preincubated with enzyme for 10 mins prior to substrate challenge ...				Eur J Med Chem 78: 106-17 (2014) Article DOI: 10.1016/j.ejmech.2014.03.035 BindingDB Entry DOI: 10.7270/Q2TD9ZVD
Government College Women University Curated by ChEMBL					More data for this Ligand-Target Pair
Cholinesterase (Equus caballus (Horse))	BDBM50004239 (CHEMBL3237455) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	49	n/a	n/a	n/a	n/a	n/a	n/a
Government College Women University Curated by ChEMBL					Assay Description Inhibition of BuChE in equine serum using butyrylthiocholine chloride as substrate preincubated with enzyme for 10 mins prior to substrate challenge ...				Eur J Med Chem 78: 106-17 (2014) Article DOI: 10.1016/j.ejmech.2014.03.035 BindingDB Entry DOI: 10.7270/Q2TD9ZVD
Government College Women University Curated by ChEMBL					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Bos taurus)	BDBM50004258 (CHEMBL3237498) Show SMILES NS(=O)(=O)c1cccc(NC(=S)NC(=O)c2cccs2)c1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	52	n/a	n/a	n/a	n/a	n/a	n/a
COMSATS Institute of Information Technology Curated by ChEMBL					Assay Description Inhibition of bovine erythrocyte carbonic anhydrase 2 using p-nitrophenyl acetate as substrate preincubated for 10 mins before substrate addition mea...				Eur J Med Chem 78: 140-50 (2014) Article DOI: 10.1016/j.ejmech.2014.03.023 BindingDB Entry DOI: 10.7270/Q2PN975X
					More data for this Ligand-Target Pair
Carboxylic ester hydrolase (Equus caballus (Horse))	BDBM173563 (1-(2-Oxo-2H-chromene-3-carbonyl)-3-(2-methoxypheny...) Show SMILES COc1ccccc1NC(=S)NC(=O)c1cc2ccccc2oc1=O Show InChI	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	60	n/a	n/a	n/a	n/a	n/a	n/a
Quaid-I-Azam University					Assay Description Newly synthesized coumarin thioureas were tested against electric eel AChE and horse serum BChE. The cholinesterase inhibitory activity was measured ...				Bioorg Chem 63: 58-63 (2015) Article DOI: 10.1016/j.bioorg.2015.09.009 BindingDB Entry DOI: 10.7270/Q2W957Z4
Quaid-I-Azam University					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] A (Rattus norvegicus (rat))	BDBM50283860 (CHEMBL4169543) Show SMILES Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	110	n/a	n/a	n/a	n/a	n/a	n/a
Government College University Curated by ChEMBL					Assay Description Inhibition of MAO-A in rat liver mitochondria using p-tyramine as substrate preincubated for 10 mins followed by substrate addition measured after 30...				Eur J Med Chem 143: 1373-1386 (2018) Article DOI: 10.1016/j.ejmech.2017.10.036 BindingDB Entry DOI: 10.7270/Q21V5HHC
Government College University Curated by ChEMBL					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] A (Rattus norvegicus (rat))	BDBM50283916 (CHEMBL1782842) Show SMILES Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	120	n/a	n/a	n/a	n/a	n/a	n/a
Government College University Curated by ChEMBL					Assay Description Inhibition of MAO-A in rat liver mitochondria using p-tyramine as substrate preincubated for 10 mins followed by substrate addition measured after 30...				Eur J Med Chem 143: 1373-1386 (2018) Article DOI: 10.1016/j.ejmech.2017.10.036 BindingDB Entry DOI: 10.7270/Q21V5HHC
Government College University Curated by ChEMBL					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Homo sapiens (Human))	BDBM50524779 (CHEMBL4447079) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	140	n/a	n/a	n/a	n/a	n/a	n/a
University of Sharjah Curated by ChEMBL					Assay Description Inhibition of human recombinant N-HA-tagged carbonic anhydrase 2 expressed in HEK293T cells using p-nitrophenyl acetate as substrate measured after 3...				Bioorg Med Chem 27: 3889-3901 (2019) Article DOI: 10.1016/j.bmc.2019.07.026 BindingDB Entry DOI: 10.7270/Q2GX4G0K
University of Sharjah Curated by ChEMBL					More data for this Ligand-Target Pair
Carbonic anhydrase 12 (Homo sapiens (Human))	BDBM50524773 (CHEMBL4533978) Show SMILES CN(C)S(=O)(=O)Oc1ccc(cc1)-c1ccc2occc2c1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	170	n/a	n/a	n/a	n/a	n/a	n/a
University of Sharjah Curated by ChEMBL					Assay Description Inhibition of human recombinant N-HA--tagged carbonic anhydrase 12 expressed in HEK293T cells using p-nitrophenyl acetate as substrate measured after...				Bioorg Med Chem 27: 3889-3901 (2019) Article DOI: 10.1016/j.bmc.2019.07.026 BindingDB Entry DOI: 10.7270/Q2GX4G0K
University of Sharjah Curated by ChEMBL					More data for this Ligand-Target Pair
Carbonic anhydrase 12 (Homo sapiens (Human))	BDBM50524777 (CHEMBL4452931) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	170	n/a	n/a	n/a	n/a	n/a	n/a
University of Sharjah Curated by ChEMBL					Assay Description Inhibition of human recombinant N-HA--tagged carbonic anhydrase 12 expressed in HEK293T cells using p-nitrophenyl acetate as substrate measured after...				Bioorg Med Chem 27: 3889-3901 (2019) Article DOI: 10.1016/j.bmc.2019.07.026 BindingDB Entry DOI: 10.7270/Q2GX4G0K
University of Sharjah Curated by ChEMBL					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] A (Rattus norvegicus (rat))	BDBM50283866 (CHEMBL475017) Show SMILES Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	177	n/a	n/a	n/a	n/a	n/a	n/a
Government College University Curated by ChEMBL					Assay Description Inhibition of MAO-A in rat liver mitochondria using p-tyramine as substrate preincubated for 10 mins followed by substrate addition measured after 30...				Eur J Med Chem 143: 1373-1386 (2018) Article DOI: 10.1016/j.ejmech.2017.10.036 BindingDB Entry DOI: 10.7270/Q21V5HHC
Government College University Curated by ChEMBL					More data for this Ligand-Target Pair
Cholinesterase (Equus caballus (Horse))	BDBM50004250 (CHEMBL3237473) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	180	n/a	n/a	n/a	n/a	n/a	n/a
Government College Women University Curated by ChEMBL					Assay Description Inhibition of BuChE in equine serum using butyrylthiocholine chloride as substrate preincubated with enzyme for 10 mins prior to substrate challenge ...				Eur J Med Chem 78: 106-17 (2014) Article DOI: 10.1016/j.ejmech.2014.03.035 BindingDB Entry DOI: 10.7270/Q2TD9ZVD
Government College Women University Curated by ChEMBL					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] B (Homo sapiens (Human))	BDBM218824 (1,2-Bis(2-octanoylimino-5-(2-methoxy-2-oxoethylide...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	200	n/a	n/a	n/a	n/a	7.4	n/a
Quaid-i-Azam University					Assay Description The assay was performed in a polystyrene 96-well plate having flat bottom containing 200 μL of the total reaction mixture. For each assay, mixtu...				Bioorg Chem 70: 17-26 (2017) Article DOI: 10.1016/j.bioorg.2016.11.004 BindingDB Entry DOI: 10.7270/Q2WM1C7Z
Quaid-i-Azam University					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] B (Homo sapiens (Human))	BDBM218823 (1,2-Bis(2-pentanoylimino-5-(2-methoxy-2-oxoethylid...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	210	n/a	n/a	n/a	n/a	7.4	n/a
Quaid-i-Azam University					Assay Description The assay was performed in a polystyrene 96-well plate having flat bottom containing 200 μL of the total reaction mixture. For each assay, mixtu...				Bioorg Chem 70: 17-26 (2017) Article DOI: 10.1016/j.bioorg.2016.11.004 BindingDB Entry DOI: 10.7270/Q2WM1C7Z
Quaid-i-Azam University					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] B (Rattus norvegicus (rat))	BDBM50283933 (CHEMBL4163328) Show SMILES COC(=O)C1=C(O)c2ccccc2S(=O)(=O)N1 \|c:4\| Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	210	n/a	n/a	n/a	n/a	n/a	n/a
Government College University Curated by ChEMBL					Assay Description Inhibition of MAO-B in rat liver mitochondria using p-tyramine as substrate preincubated for 10 mins followed by substrate addition measured after 30...				Eur J Med Chem 143: 1373-1386 (2018) Article DOI: 10.1016/j.ejmech.2017.10.036 BindingDB Entry DOI: 10.7270/Q21V5HHC
Government College University Curated by ChEMBL					More data for this Ligand-Target Pair
Ectonucleotide pyrophosphatase/phosphodiesterase family member 3 (Homo sapiens (Human))	BDBM50510596 (CHEMBL4573280) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	214	n/a	n/a	n/a	n/a	n/a	n/a
University of Sharjah Curated by ChEMBL					Assay Description Inhibition of human NPP3 expressed in African green monkey COS7 cell membranes pre-incubated for 10 mins before pNP-TMP substrate addition and furthe...				Bioorg Med Chem 27: 2741-2752 (2019) Article DOI: 10.1016/j.bmc.2019.04.031 BindingDB Entry DOI: 10.7270/Q2Q52SX7
University of Sharjah Curated by ChEMBL					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Bos taurus)	BDBM50004252 (CHEMBL3237493) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	220	n/a	n/a	n/a	n/a	n/a	n/a
COMSATS Institute of Information Technology Curated by ChEMBL					Assay Description Inhibition of bovine erythrocyte carbonic anhydrase 2 using p-nitrophenyl acetate as substrate preincubated for 10 mins before substrate addition mea...				Eur J Med Chem 78: 140-50 (2014) Article DOI: 10.1016/j.ejmech.2014.03.023 BindingDB Entry DOI: 10.7270/Q2PN975X
					More data for this Ligand-Target Pair
Acetylcholinesterase (Electrophorus electricus (Electric eel))	BDBM173571 (1-(2-Oxo-2H-chromene-3-carbonyl)-3-(2-nitrophenyl)...) Show SMILES Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	230	n/a	n/a	n/a	n/a	n/a	n/a
Quaid-I-Azam University					Assay Description Newly synthesized coumarin thioureas were tested against electric eel AChE and horse serum BChE. The cholinesterase inhibitory activity was measured ...				Bioorg Chem 63: 58-63 (2015) Article DOI: 10.1016/j.bioorg.2015.09.009 BindingDB Entry DOI: 10.7270/Q2W957Z4
Quaid-I-Azam University					More data for this Ligand-Target Pair
Ectonucleotide pyrophosphatase/phosphodiesterase family member 3 (Homo sapiens (Human))	BDBM50504119 (CHEMBL4540180) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	230	n/a	n/a	n/a	n/a	n/a	n/a
University of Sharjah Curated by ChEMBL					Assay Description Inhibition of human NPP3 expressed in COS-7 cell membranes assessed as reduction in p-nitrophenol production using pNP-TMP as substrate preincubated ...				Eur J Med Chem 181: (2019) Article DOI: 10.1016/j.ejmech.2019.07.063 BindingDB Entry DOI: 10.7270/Q2B85CD9
University of Sharjah Curated by ChEMBL					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] A (Rattus norvegicus (rat))	BDBM50283915 (CHEMBL4167042) Show SMILES Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	240	n/a	n/a	n/a	n/a	n/a	n/a
Government College University Curated by ChEMBL					Assay Description Inhibition of MAO-A in rat liver mitochondria using p-tyramine as substrate preincubated for 10 mins followed by substrate addition measured after 30...				Eur J Med Chem 143: 1373-1386 (2018) Article DOI: 10.1016/j.ejmech.2017.10.036 BindingDB Entry DOI: 10.7270/Q21V5HHC
Government College University Curated by ChEMBL					More data for this Ligand-Target Pair
Carbonic anhydrase 12 (Homo sapiens (Human))	BDBM50524780 (CHEMBL4540118) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	250	n/a	n/a	n/a	n/a	n/a	n/a
University of Sharjah Curated by ChEMBL					Assay Description Inhibition of human recombinant N-HA--tagged carbonic anhydrase 12 expressed in HEK293T cells using p-nitrophenyl acetate as substrate measured after...				Bioorg Med Chem 27: 3889-3901 (2019) Article DOI: 10.1016/j.bmc.2019.07.026 BindingDB Entry DOI: 10.7270/Q2GX4G0K
University of Sharjah Curated by ChEMBL					More data for this Ligand-Target Pair
Ectonucleotide pyrophosphatase/phosphodiesterase family member 3 (Homo sapiens (Human))	BDBM50510619 (CHEMBL4585698) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	254	n/a	n/a	n/a	n/a	n/a	n/a
University of Sharjah Curated by ChEMBL					Assay Description Inhibition of human NPP3 expressed in African green monkey COS7 cell membranes pre-incubated for 10 mins before pNP-TMP substrate addition and furthe...				Bioorg Med Chem 27: 2741-2752 (2019) Article DOI: 10.1016/j.bmc.2019.04.031 BindingDB Entry DOI: 10.7270/Q2Q52SX7
University of Sharjah Curated by ChEMBL					More data for this Ligand-Target Pair
Ectonucleotide pyrophosphatase/phosphodiesterase family member 3 (Homo sapiens (Human))	BDBM50510594 (CHEMBL4451311) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	255	n/a	n/a	n/a	n/a	n/a	n/a
University of Sharjah Curated by ChEMBL					Assay Description Inhibition of human NPP3 expressed in African green monkey COS7 cell membranes pre-incubated for 10 mins before pNP-TMP substrate addition and furthe...				Bioorg Med Chem 27: 2741-2752 (2019) Article DOI: 10.1016/j.bmc.2019.04.031 BindingDB Entry DOI: 10.7270/Q2Q52SX7
University of Sharjah Curated by ChEMBL					More data for this Ligand-Target Pair
Carbonic anhydrase 12 (Homo sapiens (Human))	BDBM50524779 (CHEMBL4447079) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	270	n/a	n/a	n/a	n/a	n/a	n/a
University of Sharjah Curated by ChEMBL					Assay Description Inhibition of human recombinant N-HA--tagged carbonic anhydrase 12 expressed in HEK293T cells using p-nitrophenyl acetate as substrate measured after...				Bioorg Med Chem 27: 3889-3901 (2019) Article DOI: 10.1016/j.bmc.2019.07.026 BindingDB Entry DOI: 10.7270/Q2GX4G0K
University of Sharjah Curated by ChEMBL					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] B (Rattus norvegicus (rat))	BDBM50283855 (CHEMBL4167829) Show SMILES COC(=O)CN1C(=O)c2ccccc2S1(=O)=O Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	270	n/a	n/a	n/a	n/a	n/a	n/a
Government College University Curated by ChEMBL					Assay Description Inhibition of MAO-B in rat liver mitochondria using p-tyramine as substrate preincubated for 10 mins followed by substrate addition measured after 30...				Eur J Med Chem 143: 1373-1386 (2018) Article DOI: 10.1016/j.ejmech.2017.10.036 BindingDB Entry DOI: 10.7270/Q21V5HHC
Government College University Curated by ChEMBL					More data for this Ligand-Target Pair
Cholinesterase (Equus caballus (Horse))	BDBM50004242 (CHEMBL3237457) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	273	n/a	n/a	n/a	n/a	n/a	n/a
Government College Women University Curated by ChEMBL					Assay Description Inhibition of BuChE in equine serum using butyrylthiocholine chloride as substrate preincubated with enzyme for 10 mins prior to substrate challenge ...				Eur J Med Chem 78: 106-17 (2014) Article DOI: 10.1016/j.ejmech.2014.03.035 BindingDB Entry DOI: 10.7270/Q2TD9ZVD
Government College Women University Curated by ChEMBL					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] B (Rattus norvegicus (rat))	BDBM50283915 (CHEMBL4167042) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	290	n/a	n/a	n/a	n/a	n/a	n/a
Government College University Curated by ChEMBL					Assay Description Inhibition of MAO-B in rat liver mitochondria using p-tyramine as substrate preincubated for 10 mins followed by substrate addition measured after 30...				Eur J Med Chem 143: 1373-1386 (2018) Article DOI: 10.1016/j.ejmech.2017.10.036 BindingDB Entry DOI: 10.7270/Q21V5HHC
Government College University Curated by ChEMBL					More data for this Ligand-Target Pair
Acetylcholinesterase (Electrophorus electricus (Electric eel))	BDBM50003958 (CHEMBL3236084) Show SMILES Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	290	n/a	n/a	n/a	n/a	n/a	n/a
Quaid-I-Azam University Curated by ChEMBL					Assay Description Inhibition of electric eel acetylcholinesterase using acetylthiocholine iodide as substrate preincubated for 10 mins before substrate addition after ...				Eur J Med Chem 78: 43-53 (2014) Article DOI: 10.1016/j.ejmech.2014.03.015 BindingDB Entry DOI: 10.7270/Q2KW5HKK
Quaid-I-Azam University Curated by ChEMBL					More data for this Ligand-Target Pair
Ectonucleotide pyrophosphatase/phosphodiesterase family member 1 (Homo sapiens (Human))	BDBM50504116 (CHEMBL4473374) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	290	n/a	n/a	n/a	n/a	n/a	n/a
University of Sharjah Curated by ChEMBL					Assay Description Inhibition of human NPP1 expressed in COS-7 cell membranes assessed as reduction in p-nitrophenol production using pNP-TMP as substrate preincubated ...				Eur J Med Chem 181: (2019) Article DOI: 10.1016/j.ejmech.2019.07.063 BindingDB Entry DOI: 10.7270/Q2B85CD9
University of Sharjah Curated by ChEMBL					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] B (Rattus norvegicus (rat))	BDBM50283851 (CHEMBL4167325) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	290	n/a	n/a	n/a	n/a	n/a	n/a
Government College University Curated by ChEMBL					Assay Description Inhibition of MAO-B in rat liver mitochondria using p-tyramine as substrate preincubated for 10 mins followed by substrate addition measured after 30...				Eur J Med Chem 143: 1373-1386 (2018) Article DOI: 10.1016/j.ejmech.2017.10.036 BindingDB Entry DOI: 10.7270/Q21V5HHC
Government College University Curated by ChEMBL					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] B (Rattus norvegicus (rat))	BDBM50283866 (CHEMBL475017) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	310	n/a	n/a	n/a	n/a	n/a	n/a
Government College University Curated by ChEMBL					Assay Description Inhibition of MAO-B in rat liver mitochondria using p-tyramine as substrate preincubated for 10 mins followed by substrate addition measured after 30...				Eur J Med Chem 143: 1373-1386 (2018) Article DOI: 10.1016/j.ejmech.2017.10.036 BindingDB Entry DOI: 10.7270/Q21V5HHC
Government College University Curated by ChEMBL					More data for this Ligand-Target Pair
Carbonic anhydrase 12 (Homo sapiens (Human))	BDBM50524768 (CHEMBL4469527) Show SMILES CCCS(=O)(=O)Oc1ccc(cc1)-c1ccc2sccc2c1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	310	n/a	n/a	n/a	n/a	n/a	n/a
University of Sharjah Curated by ChEMBL					Assay Description Inhibition of human recombinant N-HA--tagged carbonic anhydrase 12 expressed in HEK293T cells using p-nitrophenyl acetate as substrate measured after...				Bioorg Med Chem 27: 3889-3901 (2019) Article DOI: 10.1016/j.bmc.2019.07.026 BindingDB Entry DOI: 10.7270/Q2GX4G0K
University of Sharjah Curated by ChEMBL					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Homo sapiens (Human))	BDBM50524768 (CHEMBL4469527) Show SMILES CCCS(=O)(=O)Oc1ccc(cc1)-c1ccc2sccc2c1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	310	n/a	n/a	n/a	n/a	n/a	n/a
University of Sharjah Curated by ChEMBL					Assay Description Inhibition of human recombinant N-HA-tagged carbonic anhydrase 2 expressed in HEK293T cells using p-nitrophenyl acetate as substrate measured after 3...				Bioorg Med Chem 27: 3889-3901 (2019) Article DOI: 10.1016/j.bmc.2019.07.026 BindingDB Entry DOI: 10.7270/Q2GX4G0K
University of Sharjah Curated by ChEMBL					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] A (Rattus norvegicus (rat))	BDBM50283853 (CHEMBL4172849) Show SMILES Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	320	n/a	n/a	n/a	n/a	n/a	n/a
Government College University Curated by ChEMBL					Assay Description Inhibition of MAO-A in rat liver mitochondria using p-tyramine as substrate preincubated for 10 mins followed by substrate addition measured after 30...				Eur J Med Chem 143: 1373-1386 (2018) Article DOI: 10.1016/j.ejmech.2017.10.036 BindingDB Entry DOI: 10.7270/Q21V5HHC
Government College University Curated by ChEMBL					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] B (Homo sapiens (Human))	BDBM218822 (1,2-Bis(2-butanoylimino-5-(2-methoxy-2-oxoethylide...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	330	n/a	n/a	n/a	n/a	7.4	n/a
Quaid-i-Azam University					Assay Description The assay was performed in a polystyrene 96-well plate having flat bottom containing 200 μL of the total reaction mixture. For each assay, mixtu...				Bioorg Chem 70: 17-26 (2017) Article DOI: 10.1016/j.bioorg.2016.11.004 BindingDB Entry DOI: 10.7270/Q2WM1C7Z
Quaid-i-Azam University					More data for this Ligand-Target Pair

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