Found 91 hits with Last Name = 'hunt' and Initial = 'sj' Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Endothelin-1 receptor
(Homo sapiens (Human)) | BDBM50422267
![PNG](/data/jpeg/tenK5042/BindingDB_50422267.png) (CHEMBL263079)Show SMILES CCNc1cccc2c(cccc12)S(=O)(=O)Nc1ncc(Br)nc1OC Show InChI InChI=1S/C17H17BrN4O3S/c1-3-19-13-8-4-7-12-11(13)6-5-9-14(12)26(23,24)22-16-17(25-2)21-15(18)10-20-16/h4-10,19H,3H2,1-2H3,(H,20,22) | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 2.5 | n/a | n/a | n/a | n/a | n/a | n/a |
ZENECA Pharmaceuticals
Curated by ChEMBL
| Assay Description Inhibition of specific binding of [125-I]ET-1 to human endothelin A receptor |
J Med Chem 40: 996-1004 (1997)
Article DOI: 10.1021/jm9604585 BindingDB Entry DOI: 10.7270/Q25H7HKT |
More data for this Ligand-Target Pair | |
Endothelin-1 receptor
(Homo sapiens (Human)) | BDBM50422250
![PNG](/data/jpeg/tenK5042/BindingDB_50422250.png) (CHEMBL268174)Show SMILES COc1nc(C)cnc1NS(=O)(=O)c1cccc2c(cccc12)N(C)C Show InChI InChI=1S/C18H20N4O3S/c1-12-11-19-17(18(20-12)25-4)21-26(23,24)16-10-6-7-13-14(16)8-5-9-15(13)22(2)3/h5-11H,1-4H3,(H,19,21) | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 7.90 | n/a | n/a | n/a | n/a | n/a | n/a |
ZENECA Pharmaceuticals
Curated by ChEMBL
| Assay Description Inhibition of specific binding of [125-I]ET-1 to human endothelin A receptor |
J Med Chem 40: 996-1004 (1997)
Article DOI: 10.1021/jm9604585 BindingDB Entry DOI: 10.7270/Q25H7HKT |
More data for this Ligand-Target Pair | |
Endothelin-1 receptor
(Homo sapiens (Human)) | BDBM50422234
![PNG](/data/jpeg/tenK5042/BindingDB_50422234.png) (CHEMBL6412)Show SMILES COc1nc(Cl)cnc1NS(=O)(=O)c1cccc2c(cccc12)N(C)C Show InChI InChI=1S/C17H17ClN4O3S/c1-22(2)13-8-4-7-12-11(13)6-5-9-14(12)26(23,24)21-16-17(25-3)20-15(18)10-19-16/h4-10H,1-3H3,(H,19,21) | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 10 | n/a | n/a | n/a | n/a | n/a | n/a |
ZENECA Pharmaceuticals
Curated by ChEMBL
| Assay Description Inhibition of specific binding of [125-I]ET-1 to human endothelin A receptor |
J Med Chem 40: 996-1004 (1997)
Article DOI: 10.1021/jm9604585 BindingDB Entry DOI: 10.7270/Q25H7HKT |
More data for this Ligand-Target Pair | |
Endothelin-1 receptor
(Homo sapiens (Human)) | BDBM50422254
![PNG](/data/jpeg/tenK5042/BindingDB_50422254.png) (CHEMBL6785)Show SMILES CCN(C)c1cccc2c(cccc12)S(=O)(=O)Nc1ncc(Br)nc1OC Show InChI InChI=1S/C18H19BrN4O3S/c1-4-23(2)14-9-5-8-13-12(14)7-6-10-15(13)27(24,25)22-17-18(26-3)21-16(19)11-20-17/h5-11H,4H2,1-3H3,(H,20,22) | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 13 | n/a | n/a | n/a | n/a | n/a | n/a |
ZENECA Pharmaceuticals
Curated by ChEMBL
| Assay Description Inhibition of specific binding of [125-I] ET-1 to human Endothelin A receptor |
J Med Chem 40: 996-1004 (1997)
Article DOI: 10.1021/jm9604585 BindingDB Entry DOI: 10.7270/Q25H7HKT |
More data for this Ligand-Target Pair | |
Endothelin-1 receptor
(Homo sapiens (Human)) | BDBM50422257
![PNG](/data/jpeg/tenK5042/BindingDB_50422257.png) (CHEMBL6555)Show InChI InChI=1S/C16H15BrN4O3S/c1-18-12-7-3-6-11-10(12)5-4-8-13(11)25(22,23)21-15-16(24-2)20-14(17)9-19-15/h3-9,18H,1-2H3,(H,19,21) | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 16 | n/a | n/a | n/a | n/a | n/a | n/a |
ZENECA Pharmaceuticals
Curated by ChEMBL
| Assay Description Inhibition of specific binding of [125-I]ET-1 to human endothelin A receptor |
J Med Chem 40: 996-1004 (1997)
Article DOI: 10.1021/jm9604585 BindingDB Entry DOI: 10.7270/Q25H7HKT |
More data for this Ligand-Target Pair | |
Endothelin-1 receptor
(Homo sapiens (Human)) | BDBM50034435
![PNG](/data/jpeg/tenK5003/BindingDB_50034435.png) (5-Dimethylamino-naphthalene-1-sulfonic acid (3,4-d...)Show InChI InChI=1S/C17H19N3O3S/c1-11-12(2)18-23-17(11)19-24(21,22)16-10-6-7-13-14(16)8-5-9-15(13)20(3)4/h5-10,19H,1-4H3 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| Purchase
CHEMBL MCE PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 50 | n/a | n/a | n/a | n/a | n/a | n/a |
ZENECA Pharmaceuticals
Curated by ChEMBL
| Assay Description Inhibition of specific binding of [125-I]ET-1 to human endothelin A receptor |
J Med Chem 40: 996-1004 (1997)
Article DOI: 10.1021/jm9604585 BindingDB Entry DOI: 10.7270/Q25H7HKT |
More data for this Ligand-Target Pair | |
Endothelin-1 receptor
(Homo sapiens (Human)) | BDBM50422248
![PNG](/data/jpeg/tenK5042/BindingDB_50422248.png) (CHEMBL6800)Show SMILES COc1nc(Br)cnc1NS(=O)(=O)c1cccc2c(cccc12)N(C)C Show InChI InChI=1S/C17H17BrN4O3S/c1-22(2)13-8-4-7-12-11(13)6-5-9-14(12)26(23,24)21-16-17(25-3)20-15(18)10-19-16/h4-10H,1-3H3,(H,19,21) | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| Purchase
CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 63 | n/a | n/a | n/a | n/a | n/a | n/a |
ZENECA Pharmaceuticals
Curated by ChEMBL
| Assay Description Inhibition of specific binding of [125-I]ET-1 to human endothelin A receptor |
J Med Chem 40: 996-1004 (1997)
Article DOI: 10.1021/jm9604585 BindingDB Entry DOI: 10.7270/Q25H7HKT |
More data for this Ligand-Target Pair | |
Endothelin-1 receptor
(Homo sapiens (Human)) | BDBM50422244
![PNG](/data/jpeg/tenK5042/BindingDB_50422244.png) (CHEMBL268339)Show SMILES CN(C)c1cccc2c(cccc12)S(=O)(=O)Nc1cnc(Br)cn1 Show InChI InChI=1S/C16H15BrN4O2S/c1-21(2)13-7-3-6-12-11(13)5-4-8-14(12)24(22,23)20-16-10-18-15(17)9-19-16/h3-10H,1-2H3,(H,19,20) | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 126 | n/a | n/a | n/a | n/a | n/a | n/a |
ZENECA Pharmaceuticals
Curated by ChEMBL
| Assay Description Inhibition of specific binding of [125-I]ET-1 to human endothelin A receptor |
J Med Chem 40: 996-1004 (1997)
Article DOI: 10.1021/jm9604585 BindingDB Entry DOI: 10.7270/Q25H7HKT |
More data for this Ligand-Target Pair | |
Endothelin-1 receptor
(Homo sapiens (Human)) | BDBM50422246
![PNG](/data/jpeg/tenK5042/BindingDB_50422246.png) (CHEMBL6553)Show SMILES CN(C)c1cccc2c(cccc12)S(=O)(=O)Nc1cnc(Cl)cn1 Show InChI InChI=1S/C16H15ClN4O2S/c1-21(2)13-7-3-6-12-11(13)5-4-8-14(12)24(22,23)20-16-10-18-15(17)9-19-16/h3-10H,1-2H3,(H,19,20) | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 158 | n/a | n/a | n/a | n/a | n/a | n/a |
ZENECA Pharmaceuticals
Curated by ChEMBL
| Assay Description Inhibition of specific binding of [125-I]ET-1 to human endothelin A receptor |
J Med Chem 40: 996-1004 (1997)
Article DOI: 10.1021/jm9604585 BindingDB Entry DOI: 10.7270/Q25H7HKT |
More data for this Ligand-Target Pair | |
Endothelin-1 receptor
(Homo sapiens (Human)) | BDBM50422264
![PNG](/data/jpeg/tenK5042/BindingDB_50422264.png) (CHEMBL6761)Show SMILES CN(C)c1cccc2c(cccc12)S(=O)(=O)Nc1ccc(Cl)nn1 Show InChI InChI=1S/C16H15ClN4O2S/c1-21(2)13-7-3-6-12-11(13)5-4-8-14(12)24(22,23)20-16-10-9-15(17)18-19-16/h3-10H,1-2H3,(H,19,20) | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| Purchase
CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 200 | n/a | n/a | n/a | n/a | n/a | n/a |
ZENECA Pharmaceuticals
Curated by ChEMBL
| Assay Description Inhibition of specific binding of [125-I]ET-1 to human endothelin A receptor |
J Med Chem 40: 996-1004 (1997)
Article DOI: 10.1021/jm9604585 BindingDB Entry DOI: 10.7270/Q25H7HKT |
More data for this Ligand-Target Pair | |
Endothelin-1 receptor
(Homo sapiens (Human)) | BDBM50422243
![PNG](/data/jpeg/tenK5042/BindingDB_50422243.png) (CHEMBL6297)Show SMILES CN(C)c1cccc2c(cccc12)S(=O)(=O)Nc1ccc(Br)nn1 Show InChI InChI=1S/C16H15BrN4O2S/c1-21(2)13-7-3-6-12-11(13)5-4-8-14(12)24(22,23)20-16-10-9-15(17)18-19-16/h3-10H,1-2H3,(H,19,20) | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 251 | n/a | n/a | n/a | n/a | n/a | n/a |
ZENECA Pharmaceuticals
Curated by ChEMBL
| Assay Description Inhibition of specific binding of [125-I]ET-1 to human endothelin A receptor |
J Med Chem 40: 996-1004 (1997)
Article DOI: 10.1021/jm9604585 BindingDB Entry DOI: 10.7270/Q25H7HKT |
More data for this Ligand-Target Pair | |
Endothelin-1 receptor
(Homo sapiens (Human)) | BDBM50422249
![PNG](/data/jpeg/tenK5042/BindingDB_50422249.png) (CHEMBL266277)Show SMILES CN(C)c1cccc2c(cccc12)S(=O)(=O)Nc1ccc(Br)nc1 Show InChI InChI=1S/C17H16BrN3O2S/c1-21(2)15-7-3-6-14-13(15)5-4-8-16(14)24(22,23)20-12-9-10-17(18)19-11-12/h3-11,20H,1-2H3 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 251 | n/a | n/a | n/a | n/a | n/a | n/a |
ZENECA Pharmaceuticals
Curated by ChEMBL
| Assay Description Inhibition of specific binding of [125-I]ET-1 to human endothelin A receptor |
J Med Chem 40: 996-1004 (1997)
Article DOI: 10.1021/jm9604585 BindingDB Entry DOI: 10.7270/Q25H7HKT |
More data for this Ligand-Target Pair | |
Endothelin-1 receptor
(Homo sapiens (Human)) | BDBM50422233
![PNG](/data/jpeg/tenK5042/BindingDB_50422233.png) (CHEMBL6624)Show SMILES COc1ccc(NS(=O)(=O)c2cccc3c(cccc23)N(C)C)nn1 Show InChI InChI=1S/C17H18N4O3S/c1-21(2)14-8-4-7-13-12(14)6-5-9-15(13)25(22,23)20-16-10-11-17(24-3)19-18-16/h4-11H,1-3H3,(H,18,20) | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 316 | n/a | n/a | n/a | n/a | n/a | n/a |
ZENECA Pharmaceuticals
Curated by ChEMBL
| Assay Description Inhibition of specific binding of [125-I]ET-1 to human endothelin A receptor |
J Med Chem 40: 996-1004 (1997)
Article DOI: 10.1021/jm9604585 BindingDB Entry DOI: 10.7270/Q25H7HKT |
More data for this Ligand-Target Pair | |
Endothelin-1 receptor
(Homo sapiens (Human)) | BDBM50422265
![PNG](/data/jpeg/tenK5042/BindingDB_50422265.png) (CHEMBL268116)Show SMILES CN(C)c1cccc2c(cccc12)S(=O)(=O)Nc1ncc(Br)cc1C Show InChI InChI=1S/C18H18BrN3O2S/c1-12-10-13(19)11-20-18(12)21-25(23,24)17-9-5-6-14-15(17)7-4-8-16(14)22(2)3/h4-11H,1-3H3,(H,20,21) | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 316 | n/a | n/a | n/a | n/a | n/a | n/a |
ZENECA Pharmaceuticals
Curated by ChEMBL
| Assay Description Inhibition of specific binding of [125-I]ET-1 to human endothelin A receptor |
J Med Chem 40: 996-1004 (1997)
Article DOI: 10.1021/jm9604585 BindingDB Entry DOI: 10.7270/Q25H7HKT |
More data for this Ligand-Target Pair | |
Endothelin-1 receptor
(Homo sapiens (Human)) | BDBM50422241
![PNG](/data/jpeg/tenK5042/BindingDB_50422241.png) (CHEMBL415106)Show SMILES CN(C)c1cccc2c(cccc12)S(=O)(=O)Nc1nnc(Cl)cc1C Show InChI InChI=1S/C17H17ClN4O2S/c1-11-10-16(18)19-20-17(11)21-25(23,24)15-9-5-6-12-13(15)7-4-8-14(12)22(2)3/h4-10H,1-3H3,(H,20,21) | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 398 | n/a | n/a | n/a | n/a | n/a | n/a |
ZENECA Pharmaceuticals
Curated by ChEMBL
| Assay Description Inhibition of specific binding of [125-I]ET-1 to human endothelin A receptor |
J Med Chem 40: 996-1004 (1997)
Article DOI: 10.1021/jm9604585 BindingDB Entry DOI: 10.7270/Q25H7HKT |
More data for this Ligand-Target Pair | |
Endothelin-1 receptor
(Homo sapiens (Human)) | BDBM50422245
![PNG](/data/jpeg/tenK5042/BindingDB_50422245.png) (CHEMBL6588)Show SMILES CCOc1nc(Br)cnc1NS(=O)(=O)c1cccc2c(cccc12)N(C)C Show InChI InChI=1S/C18H19BrN4O3S/c1-4-26-18-17(20-11-16(19)21-18)22-27(24,25)15-10-6-7-12-13(15)8-5-9-14(12)23(2)3/h5-11H,4H2,1-3H3,(H,20,22) | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 501 | n/a | n/a | n/a | n/a | n/a | n/a |
ZENECA Pharmaceuticals
Curated by ChEMBL
| Assay Description Inhibition of specific binding of [125-I]ET-1 to human endothelin A receptor |
J Med Chem 40: 996-1004 (1997)
Article DOI: 10.1021/jm9604585 BindingDB Entry DOI: 10.7270/Q25H7HKT |
More data for this Ligand-Target Pair | |
Endothelin-1 receptor
(Homo sapiens (Human)) | BDBM50422266
![PNG](/data/jpeg/tenK5042/BindingDB_50422266.png) (CHEMBL7019)Show SMILES CN(C)c1cccc2c(cccc12)S(=O)(=O)Nc1cnc(Br)nc1 Show InChI InChI=1S/C16H15BrN4O2S/c1-21(2)14-7-3-6-13-12(14)5-4-8-15(13)24(22,23)20-11-9-18-16(17)19-10-11/h3-10,20H,1-2H3 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 631 | n/a | n/a | n/a | n/a | n/a | n/a |
ZENECA Pharmaceuticals
Curated by ChEMBL
| Assay Description Inhibition of specific binding of [125-I]ET-1 to human endothelin A receptor |
J Med Chem 40: 996-1004 (1997)
Article DOI: 10.1021/jm9604585 BindingDB Entry DOI: 10.7270/Q25H7HKT |
More data for this Ligand-Target Pair | |
Endothelin-1 receptor
(Homo sapiens (Human)) | BDBM50422263
![PNG](/data/jpeg/tenK5042/BindingDB_50422263.png) (CHEMBL6382)Show SMILES CN(C)c1cccc2c(cccc12)S(=O)(=O)Nc1ncc(Br)nc1C Show InChI InChI=1S/C17H17BrN4O2S/c1-11-17(19-10-16(18)20-11)21-25(23,24)15-9-5-6-12-13(15)7-4-8-14(12)22(2)3/h4-10H,1-3H3,(H,19,21) | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 631 | n/a | n/a | n/a | n/a | n/a | n/a |
ZENECA Pharmaceuticals
Curated by ChEMBL
| Assay Description Inhibition of specific binding of [125-I]ET-1 to human endothelin A receptor |
J Med Chem 40: 996-1004 (1997)
Article DOI: 10.1021/jm9604585 BindingDB Entry DOI: 10.7270/Q25H7HKT |
More data for this Ligand-Target Pair | |
Endothelin-1 receptor
(Homo sapiens (Human)) | BDBM50422258
![PNG](/data/jpeg/tenK5042/BindingDB_50422258.png) (CHEMBL6399)Show InChI InChI=1S/C16H16N4O2S/c1-20(2)14-7-3-6-13-12(14)5-4-8-15(13)23(21,22)19-16-11-17-9-10-18-16/h3-11H,1-2H3,(H,18,19) | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
ZENECA Pharmaceuticals
Curated by ChEMBL
| Assay Description Inhibition of specific binding of [125-I]ET-1 to human endothelin A receptor |
J Med Chem 40: 996-1004 (1997)
Article DOI: 10.1021/jm9604585 BindingDB Entry DOI: 10.7270/Q25H7HKT |
More data for this Ligand-Target Pair | |
Endothelin-1 receptor
(Homo sapiens (Human)) | BDBM50422253
![PNG](/data/jpeg/tenK5042/BindingDB_50422253.png) (CHEMBL6583)Show InChI InChI=1S/C17H18N4O2S/c1-12-10-19-17(11-18-12)20-24(22,23)16-9-5-6-13-14(16)7-4-8-15(13)21(2)3/h4-11H,1-3H3,(H,19,20) | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.26E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
ZENECA Pharmaceuticals
Curated by ChEMBL
| Assay Description Inhibition of specific binding of [125-I]ET-1 to human endothelin A receptor |
J Med Chem 40: 996-1004 (1997)
Article DOI: 10.1021/jm9604585 BindingDB Entry DOI: 10.7270/Q25H7HKT |
More data for this Ligand-Target Pair | |
Endothelin-1 receptor
(Homo sapiens (Human)) | BDBM50422261
![PNG](/data/jpeg/tenK5042/BindingDB_50422261.png) (CHEMBL415292)Show SMILES CN(C)c1cccc2c(cccc12)S(=O)(=O)Nc1ccc(Cl)nc1 Show InChI InChI=1S/C17H16ClN3O2S/c1-21(2)15-7-3-6-14-13(15)5-4-8-16(14)24(22,23)20-12-9-10-17(18)19-11-12/h3-11,20H,1-2H3 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 1.26E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
ZENECA Pharmaceuticals
Curated by ChEMBL
| Assay Description Inhibition of specific binding of [125-I]ET-1 to human endothelin A receptor |
J Med Chem 40: 996-1004 (1997)
Article DOI: 10.1021/jm9604585 BindingDB Entry DOI: 10.7270/Q25H7HKT |
More data for this Ligand-Target Pair | |
Endothelin-1 receptor
(Homo sapiens (Human)) | BDBM50422240
![PNG](/data/jpeg/tenK5042/BindingDB_50422240.png) (CHEMBL6411)Show SMILES CN(C)c1cccc2c(cccc12)S(=O)(=O)Nc1ccc(Br)cn1 Show InChI InChI=1S/C17H16BrN3O2S/c1-21(2)15-7-3-6-14-13(15)5-4-8-16(14)24(22,23)20-17-10-9-12(18)11-19-17/h3-11H,1-2H3,(H,19,20) | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.59E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
ZENECA Pharmaceuticals
Curated by ChEMBL
| Assay Description Inhibition of specific binding of [125-I]ET-1 to human endothelin A receptor |
J Med Chem 40: 996-1004 (1997)
Article DOI: 10.1021/jm9604585 BindingDB Entry DOI: 10.7270/Q25H7HKT |
More data for this Ligand-Target Pair | |
Endothelin-1 receptor
(Homo sapiens (Human)) | BDBM50422236
![PNG](/data/jpeg/tenK5042/BindingDB_50422236.png) (CHEMBL6463)Show InChI InChI=1S/C18H19N3O2S/c1-13-10-11-18(19-12-13)20-24(22,23)17-9-5-6-14-15(17)7-4-8-16(14)21(2)3/h4-12H,1-3H3,(H,19,20) | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 1.59E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
ZENECA Pharmaceuticals
Curated by ChEMBL
| Assay Description Inhibition of specific binding of [125-I]ET-1 to human endothelin A receptor |
J Med Chem 40: 996-1004 (1997)
Article DOI: 10.1021/jm9604585 BindingDB Entry DOI: 10.7270/Q25H7HKT |
More data for this Ligand-Target Pair | |
Endothelin-1 receptor
(Homo sapiens (Human)) | BDBM50422262
![PNG](/data/jpeg/tenK5042/BindingDB_50422262.png) (CHEMBL6433)Show SMILES CN(C)c1cccc2c(cccc12)S(=O)(=O)Nc1ncc(Cl)cn1 Show InChI InChI=1S/C16H15ClN4O2S/c1-21(2)14-7-3-6-13-12(14)5-4-8-15(13)24(22,23)20-16-18-9-11(17)10-19-16/h3-10H,1-2H3,(H,18,19,20) | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.59E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
ZENECA Pharmaceuticals
Curated by ChEMBL
| Assay Description Inhibition of specific binding of [125-I]ET-1 to human endothelin A receptor |
J Med Chem 40: 996-1004 (1997)
Article DOI: 10.1021/jm9604585 BindingDB Entry DOI: 10.7270/Q25H7HKT |
More data for this Ligand-Target Pair | |
Endothelin-1 receptor
(Homo sapiens (Human)) | BDBM50422256
![PNG](/data/jpeg/tenK5042/BindingDB_50422256.png) (CHEMBL268387)Show InChI InChI=1S/C17H18N4O2S/c1-12-10-11-17(19-18-12)20-24(22,23)16-9-5-6-13-14(16)7-4-8-15(13)21(2)3/h4-11H,1-3H3,(H,19,20) | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 1.59E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
ZENECA Pharmaceuticals
Curated by ChEMBL
| Assay Description Inhibition of specific binding of [125-I]ET-1 to human endothelin A receptor |
J Med Chem 40: 996-1004 (1997)
Article DOI: 10.1021/jm9604585 BindingDB Entry DOI: 10.7270/Q25H7HKT |
More data for this Ligand-Target Pair | |
Endothelin-1 receptor
(Homo sapiens (Human)) | BDBM50422255
![PNG](/data/jpeg/tenK5042/BindingDB_50422255.png) (CHEMBL6630)Show SMILES CN(C)c1cccc2c(cccc12)S(=O)(=O)Nc1ncc(Br)cn1 Show InChI InChI=1S/C16H15BrN4O2S/c1-21(2)14-7-3-6-13-12(14)5-4-8-15(13)24(22,23)20-16-18-9-11(17)10-19-16/h3-10H,1-2H3,(H,18,19,20) | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 2.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
ZENECA Pharmaceuticals
Curated by ChEMBL
| Assay Description Inhibition of specific binding of [125-I]ET-1 to human endothelin A receptor |
J Med Chem 40: 996-1004 (1997)
Article DOI: 10.1021/jm9604585 BindingDB Entry DOI: 10.7270/Q25H7HKT |
More data for this Ligand-Target Pair | |
Endothelin-1 receptor
(Homo sapiens (Human)) | BDBM50422238
![PNG](/data/jpeg/tenK5042/BindingDB_50422238.png) (CHEMBL6576)Show InChI InChI=1S/C15H12BrN3O3S/c1-22-15-14(17-9-13(16)18-15)19-23(20,21)12-8-4-6-10-5-2-3-7-11(10)12/h2-9H,1H3,(H,17,19) | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 2.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
ZENECA Pharmaceuticals
Curated by ChEMBL
| Assay Description Inhibition of specific binding of [125-I]ET-1 to human endothelin A receptor |
J Med Chem 40: 996-1004 (1997)
Article DOI: 10.1021/jm9604585 BindingDB Entry DOI: 10.7270/Q25H7HKT |
More data for this Ligand-Target Pair | |
Endothelin-1 receptor
(Homo sapiens (Human)) | BDBM50422237
![PNG](/data/jpeg/tenK5042/BindingDB_50422237.png) (CHEMBL266315)Show SMILES CN(C)c1cccc2c(cccc12)S(=O)(=O)Nc1ccc(Cl)cn1 Show InChI InChI=1S/C17H16ClN3O2S/c1-21(2)15-7-3-6-14-13(15)5-4-8-16(14)24(22,23)20-17-10-9-12(18)11-19-17/h3-11H,1-2H3,(H,19,20) | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 2.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
ZENECA Pharmaceuticals
Curated by ChEMBL
| Assay Description Inhibition of specific binding of [125-I]ET-1 to human endothelin A receptor |
J Med Chem 40: 996-1004 (1997)
Article DOI: 10.1021/jm9604585 BindingDB Entry DOI: 10.7270/Q25H7HKT |
More data for this Ligand-Target Pair | |
Endothelin-1 receptor
(Homo sapiens (Human)) | BDBM50422247
![PNG](/data/jpeg/tenK5042/BindingDB_50422247.png) (CHEMBL6543)Show SMILES CCc1nc(Br)cnc1NS(=O)(=O)c1cccc2c(cccc12)N(C)C Show InChI InChI=1S/C18H19BrN4O2S/c1-4-14-18(20-11-17(19)21-14)22-26(24,25)16-10-6-7-12-13(16)8-5-9-15(12)23(2)3/h5-11H,4H2,1-3H3,(H,20,22) | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 2.51E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
ZENECA Pharmaceuticals
Curated by ChEMBL
| Assay Description Inhibition of specific binding of [125-I]ET-1 to human endothelin A receptor |
J Med Chem 40: 996-1004 (1997)
Article DOI: 10.1021/jm9604585 BindingDB Entry DOI: 10.7270/Q25H7HKT |
More data for this Ligand-Target Pair | |
Endothelin-1 receptor
(Homo sapiens (Human)) | BDBM50422242
![PNG](/data/jpeg/tenK5042/BindingDB_50422242.png) (CHEMBL6400)Show SMILES CN(C)c1cccc2c(cccc12)S(=O)(=O)Nc1ccc(Br)cc1 Show InChI InChI=1S/C18H17BrN2O2S/c1-21(2)17-7-3-6-16-15(17)5-4-8-18(16)24(22,23)20-14-11-9-13(19)10-12-14/h3-12,20H,1-2H3 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 3.16E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
ZENECA Pharmaceuticals
Curated by ChEMBL
| Assay Description Inhibition of specific binding of [125-I]ET-1 to human endothelin A receptor |
J Med Chem 40: 996-1004 (1997)
Article DOI: 10.1021/jm9604585 BindingDB Entry DOI: 10.7270/Q25H7HKT |
More data for this Ligand-Target Pair | |
Endothelin-1 receptor
(Homo sapiens (Human)) | BDBM50422232
![PNG](/data/jpeg/tenK5042/BindingDB_50422232.png) (CHEMBL269237)Show SMILES CCOc1ccc(NS(=O)(=O)c2cccc3c(cccc23)N(C)C)nn1 Show InChI InChI=1S/C18H20N4O3S/c1-4-25-18-12-11-17(19-20-18)21-26(23,24)16-10-6-7-13-14(16)8-5-9-15(13)22(2)3/h5-12H,4H2,1-3H3,(H,19,21) | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 3.98E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
ZENECA Pharmaceuticals
Curated by ChEMBL
| Assay Description Inhibition of specific binding of [125-I]ET-1 to human endothelin A receptor |
J Med Chem 40: 996-1004 (1997)
Article DOI: 10.1021/jm9604585 BindingDB Entry DOI: 10.7270/Q25H7HKT |
More data for this Ligand-Target Pair | |
Endothelin-1 receptor
(Homo sapiens (Human)) | BDBM50422251
![PNG](/data/jpeg/tenK5042/BindingDB_50422251.png) (CHEMBL6660)Show SMILES CN(C)c1cccc2c(cccc12)S(=O)(=O)Nc1cc(C)c(Cl)nn1 Show InChI InChI=1S/C17H17ClN4O2S/c1-11-10-16(19-20-17(11)18)21-25(23,24)15-9-5-6-12-13(15)7-4-8-14(12)22(2)3/h4-10H,1-3H3,(H,19,21) | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 5.01E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
ZENECA Pharmaceuticals
Curated by ChEMBL
| Assay Description Inhibition of specific binding of [125-I]ET-1 to human endothelin A receptor |
J Med Chem 40: 996-1004 (1997)
Article DOI: 10.1021/jm9604585 BindingDB Entry DOI: 10.7270/Q25H7HKT |
More data for this Ligand-Target Pair | |
Endothelin-1 receptor
(Homo sapiens (Human)) | BDBM50422259
![PNG](/data/jpeg/tenK5042/BindingDB_50422259.png) (CHEMBL266684)Show InChI InChI=1S/C17H16IN3O2S/c1-21(2)15-7-3-6-14-13(15)5-4-8-16(14)24(22,23)20-17-10-9-12(18)11-19-17/h3-11H,1-2H3,(H,19,20) | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 5.01E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
ZENECA Pharmaceuticals
Curated by ChEMBL
| Assay Description Inhibition of specific binding of [125-I]ET-1 to human endothelin A receptor |
J Med Chem 40: 996-1004 (1997)
Article DOI: 10.1021/jm9604585 BindingDB Entry DOI: 10.7270/Q25H7HKT |
More data for this Ligand-Target Pair | |
Endothelin-1 receptor
(Homo sapiens (Human)) | BDBM50422235
![PNG](/data/jpeg/tenK5042/BindingDB_50422235.png) (CHEMBL6647)Show SMILES CN(C)c1cccc2c(cccc12)S(=O)(=O)Nc1ncc(Br)[nH]c1=O Show InChI InChI=1S/C16H15BrN4O3S/c1-21(2)12-7-3-6-11-10(12)5-4-8-13(11)25(23,24)20-15-16(22)19-14(17)9-18-15/h3-9H,1-2H3,(H,18,20)(H,19,22) | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 5.01E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
ZENECA Pharmaceuticals
Curated by ChEMBL
| Assay Description Inhibition of specific binding of [125-I]ET-1 to human endothelin A receptor |
J Med Chem 40: 996-1004 (1997)
Article DOI: 10.1021/jm9604585 BindingDB Entry DOI: 10.7270/Q25H7HKT |
More data for this Ligand-Target Pair | |
Endothelin-1 receptor
(Homo sapiens (Human)) | BDBM50422239
![PNG](/data/jpeg/tenK5042/BindingDB_50422239.png) (CHEMBL6468)Show InChI InChI=1S/C16H16N4O2S/c1-20(2)14-8-3-7-13-12(14)6-4-9-15(13)23(21,22)19-16-17-10-5-11-18-16/h3-11H,1-2H3,(H,17,18,19) | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 6.31E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
ZENECA Pharmaceuticals
Curated by ChEMBL
| Assay Description Inhibition of specific binding of [125-I]ET-1 to human endothelin A receptor |
J Med Chem 40: 996-1004 (1997)
Article DOI: 10.1021/jm9604585 BindingDB Entry DOI: 10.7270/Q25H7HKT |
More data for this Ligand-Target Pair | |
Endothelin-1 receptor
(Homo sapiens (Human)) | BDBM50422252
![PNG](/data/jpeg/tenK5042/BindingDB_50422252.png) (CHEMBL6778)Show SMILES CN(C)c1cccc2c(cccc12)S(=O)(=O)Nc1ccc(Cl)cc1 Show InChI InChI=1S/C18H17ClN2O2S/c1-21(2)17-7-3-6-16-15(17)5-4-8-18(16)24(22,23)20-14-11-9-13(19)10-12-14/h3-12,20H,1-2H3 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 7.94E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
ZENECA Pharmaceuticals
Curated by ChEMBL
| Assay Description Inhibition of specific binding of [125-I]ET-1 to human endothelin A receptor |
J Med Chem 40: 996-1004 (1997)
Article DOI: 10.1021/jm9604585 BindingDB Entry DOI: 10.7270/Q25H7HKT |
More data for this Ligand-Target Pair | |
Endothelin-1 receptor
(Homo sapiens (Human)) | BDBM50422260
![PNG](/data/jpeg/tenK5042/BindingDB_50422260.png) (CHEMBL6566)Show SMILES CN(C)c1cccc2c(cccc12)S(=O)(=O)Nc1ccc(Br)c(C)n1 Show InChI InChI=1S/C18H18BrN3O2S/c1-12-15(19)10-11-18(20-12)21-25(23,24)17-9-5-6-13-14(17)7-4-8-16(13)22(2)3/h4-11H,1-3H3,(H,20,21) | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
ZENECA Pharmaceuticals
Curated by ChEMBL
| Assay Description Inhibition of specific binding of [125-I]ET-1 to human endothelin A receptor |
J Med Chem 40: 996-1004 (1997)
Article DOI: 10.1021/jm9604585 BindingDB Entry DOI: 10.7270/Q25H7HKT |
More data for this Ligand-Target Pair | |
G protein-activated inward rectifier potassium channel 4
(Homo sapiens (Human)) | BDBM50439402
![PNG](/data/jpeg/tenK5043/BindingDB_50439402.png) (CHEMBL2420537)Show InChI InChI=1S/C17H19BrN2O3S/c1-12-8-9-14(11-16(12)24(22,23)20(2)3)19-17(21)10-13-6-4-5-7-15(13)18/h4-9,11H,10H2,1-3H3,(H,19,21) | Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | n/a | n/a | 1.60E+3 | n/a | n/a | n/a | n/a |
Vanderbilt University
Curated by ChEMBL
| Assay Description Activation of GIRK1/4 (unknown origin) by cell-based thallium flux assay |
Bioorg Med Chem Lett 23: 5195-8 (2013)
Article DOI: 10.1016/j.bmcl.2013.07.002 BindingDB Entry DOI: 10.7270/Q28K7BG1 |
More data for this Ligand-Target Pair | |
G protein-activated inward rectifier potassium channel 4
(Homo sapiens (Human)) | BDBM50439403
![PNG](/data/jpeg/tenK5043/BindingDB_50439403.png) (CHEMBL1558022)Show InChI InChI=1S/C17H19ClN2O3S/c1-12-8-9-14(11-16(12)24(22,23)20(2)3)19-17(21)10-13-6-4-5-7-15(13)18/h4-9,11H,10H2,1-3H3,(H,19,21) | Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| Purchase
CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 1.10E+3 | n/a | n/a | n/a | n/a |
Vanderbilt University
Curated by ChEMBL
| Assay Description Activation of GIRK1/4 (unknown origin) by cell-based thallium flux assay |
Bioorg Med Chem Lett 23: 5195-8 (2013)
Article DOI: 10.1016/j.bmcl.2013.07.002 BindingDB Entry DOI: 10.7270/Q28K7BG1 |
More data for this Ligand-Target Pair | |
G protein-activated inward rectifier potassium channel 4
(Homo sapiens (Human)) | BDBM50437983
![PNG](/data/jpeg/tenK5043/BindingDB_50437983.png) (CHEMBL2409106)Show InChI InChI=1S/C17H14F2N4O/c1-11-9-16(23(22-11)13-5-3-2-4-6-13)21-17(24)20-12-7-8-14(18)15(19)10-12/h2-10H,1H3,(H2,20,21,24) | Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| Purchase
CHEMBL MCE PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 1.80E+3 | n/a | n/a | n/a | n/a |
Vanderbilt University
Curated by ChEMBL
| Assay Description Activation of GIRK1/4 (unknown origin) by cell-based thallium flux assay |
Bioorg Med Chem Lett 23: 5195-8 (2013)
Article DOI: 10.1016/j.bmcl.2013.07.002 BindingDB Entry DOI: 10.7270/Q28K7BG1 |
More data for this Ligand-Target Pair | |
G protein-activated inward rectifier potassium channel 4
(Homo sapiens (Human)) | BDBM50115223
![PNG](/data/jpeg/tenK5011/BindingDB_50115223.png) (1-(5-Methyl-2-phenyl-2H-pyrazol-3-yl)-3-phenyl-ure...)Show InChI InChI=1S/C17H16N4O/c1-13-12-16(21(20-13)15-10-6-3-7-11-15)19-17(22)18-14-8-4-2-5-9-14/h2-12H,1H3,(H2,18,19,22) | Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| Purchase
CHEMBL MCE PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 690 | n/a | n/a | n/a | n/a |
Vanderbilt University
Curated by ChEMBL
| Assay Description Activation of GIRK1/4 (unknown origin) by cell-based thallium flux assay |
Bioorg Med Chem Lett 23: 5195-8 (2013)
Article DOI: 10.1016/j.bmcl.2013.07.002 BindingDB Entry DOI: 10.7270/Q28K7BG1 |
More data for this Ligand-Target Pair | |
G protein-activated inward rectifier potassium channel 1
(Homo sapiens (Human)) | BDBM50439404
![PNG](/data/jpeg/tenK5043/BindingDB_50439404.png) (CHEMBL2420539)Show SMILES CN(C)S(=O)(=O)c1cc(NC(=O)Cc2ccc(F)cc2)ccc1C Show InChI InChI=1S/C17H19FN2O3S/c1-12-4-9-15(11-16(12)24(22,23)20(2)3)19-17(21)10-13-5-7-14(18)8-6-13/h4-9,11H,10H2,1-3H3,(H,19,21) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| Purchase
CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 3.60E+3 | n/a | n/a | n/a | n/a |
Vanderbilt University
Curated by ChEMBL
| Assay Description Activation of GIRK1/2 (unknown origin) by cell-based thallium flux assay |
Bioorg Med Chem Lett 23: 5195-8 (2013)
Article DOI: 10.1016/j.bmcl.2013.07.002 BindingDB Entry DOI: 10.7270/Q28K7BG1 |
More data for this Ligand-Target Pair | |
G protein-activated inward rectifier potassium channel 1
(Homo sapiens (Human)) | BDBM95731
![PNG](/data/jpeg/tenK9/BindingDB_95731.png) (2-(4-chlorophenyl)-N-[3-(dimethylsulfamoyl)phenyl]...)Show SMILES CN(C)S(=O)(=O)c1cccc(NC(=O)Cc2ccc(Cl)cc2)c1 Show InChI InChI=1S/C16H17ClN2O3S/c1-19(2)23(21,22)15-5-3-4-14(11-15)18-16(20)10-12-6-8-13(17)9-7-12/h3-9,11H,10H2,1-2H3,(H,18,20) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
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PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 2.30E+3 | n/a | n/a | n/a | n/a |
Vanderbilt University
Curated by ChEMBL
| Assay Description Activation of GIRK1/2 (unknown origin) by cell-based thallium flux assay |
Bioorg Med Chem Lett 23: 5195-8 (2013)
Article DOI: 10.1016/j.bmcl.2013.07.002 BindingDB Entry DOI: 10.7270/Q28K7BG1 |
More data for this Ligand-Target Pair | |
G protein-activated inward rectifier potassium channel 1
(Homo sapiens (Human)) | BDBM50439405
![PNG](/data/jpeg/tenK5043/BindingDB_50439405.png) (CHEMBL2420538)Show InChI InChI=1S/C16H17ClN2O3S/c1-19(2)23(21,22)14-8-5-7-13(11-14)18-16(20)10-12-6-3-4-9-15(12)17/h3-9,11H,10H2,1-2H3,(H,18,20) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| Purchase
CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 3.30E+3 | n/a | n/a | n/a | n/a |
Vanderbilt University
Curated by ChEMBL
| Assay Description Activation of GIRK1/2 (unknown origin) by cell-based thallium flux assay |
Bioorg Med Chem Lett 23: 5195-8 (2013)
Article DOI: 10.1016/j.bmcl.2013.07.002 BindingDB Entry DOI: 10.7270/Q28K7BG1 |
More data for this Ligand-Target Pair | |
G protein-activated inward rectifier potassium channel 1
(Homo sapiens (Human)) | BDBM50439402
![PNG](/data/jpeg/tenK5043/BindingDB_50439402.png) (CHEMBL2420537)Show InChI InChI=1S/C17H19BrN2O3S/c1-12-8-9-14(11-16(12)24(22,23)20(2)3)19-17(21)10-13-6-4-5-7-15(13)18/h4-9,11H,10H2,1-3H3,(H,19,21) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | n/a | n/a | 1.40E+3 | n/a | n/a | n/a | n/a |
Vanderbilt University
Curated by ChEMBL
| Assay Description Activation of GIRK1/2 (unknown origin) by cell-based thallium flux assay |
Bioorg Med Chem Lett 23: 5195-8 (2013)
Article DOI: 10.1016/j.bmcl.2013.07.002 BindingDB Entry DOI: 10.7270/Q28K7BG1 |
More data for this Ligand-Target Pair | |
G protein-activated inward rectifier potassium channel 1
(Homo sapiens (Human)) | BDBM50439403
![PNG](/data/jpeg/tenK5043/BindingDB_50439403.png) (CHEMBL1558022)Show InChI InChI=1S/C17H19ClN2O3S/c1-12-8-9-14(11-16(12)24(22,23)20(2)3)19-17(21)10-13-6-4-5-7-15(13)18/h4-9,11H,10H2,1-3H3,(H,19,21) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| Purchase
CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 1.10E+3 | n/a | n/a | n/a | n/a |
Vanderbilt University
Curated by ChEMBL
| Assay Description Activation of GIRK1/2 (unknown origin) by cell-based thallium flux assay |
Bioorg Med Chem Lett 23: 5195-8 (2013)
Article DOI: 10.1016/j.bmcl.2013.07.002 BindingDB Entry DOI: 10.7270/Q28K7BG1 |
More data for this Ligand-Target Pair | |
G protein-activated inward rectifier potassium channel 1
(Homo sapiens (Human)) | BDBM50437983
![PNG](/data/jpeg/tenK5043/BindingDB_50437983.png) (CHEMBL2409106)Show InChI InChI=1S/C17H14F2N4O/c1-11-9-16(23(22-11)13-5-3-2-4-6-13)21-17(24)20-12-7-8-14(18)15(19)10-12/h2-10H,1H3,(H2,20,21,24) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| Purchase
CHEMBL MCE PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 160 | n/a | n/a | n/a | n/a |
Vanderbilt University
Curated by ChEMBL
| Assay Description Activation of GIRK1/2 (unknown origin) by cell-based thallium flux assay |
Bioorg Med Chem Lett 23: 5195-8 (2013)
Article DOI: 10.1016/j.bmcl.2013.07.002 BindingDB Entry DOI: 10.7270/Q28K7BG1 |
More data for this Ligand-Target Pair | |
G protein-activated inward rectifier potassium channel 1
(Homo sapiens (Human)) | BDBM50115223
![PNG](/data/jpeg/tenK5011/BindingDB_50115223.png) (1-(5-Methyl-2-phenyl-2H-pyrazol-3-yl)-3-phenyl-ure...)Show InChI InChI=1S/C17H16N4O/c1-13-12-16(21(20-13)15-10-6-3-7-11-15)19-17(22)18-14-8-4-2-5-9-14/h2-12H,1H3,(H2,18,19,22) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| Purchase
CHEMBL MCE PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 1.40E+3 | n/a | n/a | n/a | n/a |
Vanderbilt University
Curated by ChEMBL
| Assay Description Activation of GIRK1/2 (unknown origin) by cell-based thallium flux assay |
Bioorg Med Chem Lett 23: 5195-8 (2013)
Article DOI: 10.1016/j.bmcl.2013.07.002 BindingDB Entry DOI: 10.7270/Q28K7BG1 |
More data for this Ligand-Target Pair | |
G protein-activated inward rectifier potassium channel 4
(Homo sapiens (Human)) | BDBM50241582
![PNG](/data/jpeg/tenK5024/BindingDB_50241582.png) ((S)-7-((2S,3R,4S,5S,6R)-4,5-dihydroxy-6-(hydroxyme...)Show SMILES C[C@@H]1O[C@@H](O[C@@H]2[C@@H](O)[C@H](O)[C@@H](CO)O[C@H]2Oc2cc(O)c3C(=O)C[C@H](Oc3c2)c2ccc(O)cc2)[C@H](O)[C@H](O)[C@H]1O |r| Show InChI InChI=1S/C27H32O14/c1-10-20(32)22(34)24(36)26(37-10)41-25-23(35)21(33)18(9-28)40-27(25)38-13-6-14(30)19-15(31)8-16(39-17(19)7-13)11-2-4-12(29)5-3-11/h2-7,10,16,18,20-30,32-36H,8-9H2,1H3/t10-,16-,18+,20-,21+,22+,23-,24+,25+,26-,27+/m0/s1 | Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
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CHEMBL MCE KEGG PC cid PC sid PDB UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a |
Vanderbilt University
Curated by ChEMBL
| Assay Description Activation of recombinant human GIRK1/4 expressed in Xenopus oocytes by two-electrode voltage clamp method |
Bioorg Med Chem Lett 23: 5195-8 (2013)
Article DOI: 10.1016/j.bmcl.2013.07.002 BindingDB Entry DOI: 10.7270/Q28K7BG1 |
More data for this Ligand-Target Pair | |
G protein-activated inward rectifier potassium channel 1
(Homo sapiens (Human)) | BDBM50241582
![PNG](/data/jpeg/tenK5024/BindingDB_50241582.png) ((S)-7-((2S,3R,4S,5S,6R)-4,5-dihydroxy-6-(hydroxyme...)Show SMILES C[C@@H]1O[C@@H](O[C@@H]2[C@@H](O)[C@H](O)[C@@H](CO)O[C@H]2Oc2cc(O)c3C(=O)C[C@H](Oc3c2)c2ccc(O)cc2)[C@H](O)[C@H](O)[C@H]1O |r| Show InChI InChI=1S/C27H32O14/c1-10-20(32)22(34)24(36)26(37-10)41-25-23(35)21(33)18(9-28)40-27(25)38-13-6-14(30)19-15(31)8-16(39-17(19)7-13)11-2-4-12(29)5-3-11/h2-7,10,16,18,20-30,32-36H,8-9H2,1H3/t10-,16-,18+,20-,21+,22+,23-,24+,25+,26-,27+/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| Purchase
CHEMBL MCE KEGG PC cid PC sid PDB UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a |
Vanderbilt University
Curated by ChEMBL
| Assay Description Activation of recombinant human GIRK1/2 expressed in Xenopus oocytes by two-electrode voltage clamp method |
Bioorg Med Chem Lett 23: 5195-8 (2013)
Article DOI: 10.1016/j.bmcl.2013.07.002 BindingDB Entry DOI: 10.7270/Q28K7BG1 |
More data for this Ligand-Target Pair | |