Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Oligo-1,6-glucosidase IMA1 (Saccharomyces cerevisiae S288c (Baker's yeast)) | BDBM178004 (2-(3-((3-(trifluoromethyl)benzyl)oxy)phenyl)-4H-ch...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.26E+3 | n/a | n/a | n/a | n/a | 6.8 | n/a |
Universiti Teknologi MARA | Assay Description The α-glucosidase inhibition assay had been carried out using baker¿s yeast a-glucosidase (EC 3.2.1.20) and p-nitrophenyl-α-D-glucopyranosi... | Chem Biol Drug Des 87: 361-73 (2016) Article DOI: 10.1111/cbdd.12666 BindingDB Entry DOI: 10.7270/Q2HQ3XPS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Oligo-1,6-glucosidase IMA1 (Saccharomyces cerevisiae S288c (Baker's yeast)) | BDBM178010 (2-(3-((2,3-difluorobenzyl)oxy)phenyl)-4H-chromen-4...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 3.49E+3 | n/a | n/a | n/a | n/a | 6.8 | n/a |
Universiti Teknologi MARA | Assay Description The α-glucosidase inhibition assay had been carried out using baker¿s yeast a-glucosidase (EC 3.2.1.20) and p-nitrophenyl-α-D-glucopyranosi... | Chem Biol Drug Des 87: 361-73 (2016) Article DOI: 10.1111/cbdd.12666 BindingDB Entry DOI: 10.7270/Q2HQ3XPS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Oligo-1,6-glucosidase IMA1 (Saccharomyces cerevisiae S288c (Baker's yeast)) | BDBM178004 (2-(3-((3-(trifluoromethyl)benzyl)oxy)phenyl)-4H-ch...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 5.45E+3 | n/a | n/a | n/a | n/a | 6.8 | n/a |
Universiti Teknologi MARA | Assay Description The α-glucosidase inhibition assay had been carried out using baker¿s yeast a-glucosidase (EC 3.2.1.20) and p-nitrophenyl-α-D-glucopyranosi... | Chem Biol Drug Des 87: 361-73 (2016) Article DOI: 10.1111/cbdd.12666 BindingDB Entry DOI: 10.7270/Q2HQ3XPS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Oligo-1,6-glucosidase IMA1 (Saccharomyces cerevisiae S288c (Baker's yeast)) | BDBM178007 (2-(3-((3-((trifluoromethyl)thio)benzyl)oxy)phenyl)...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 8.66E+3 | n/a | n/a | n/a | n/a | 6.8 | n/a |
Universiti Teknologi MARA | Assay Description The α-glucosidase inhibition assay had been carried out using baker¿s yeast a-glucosidase (EC 3.2.1.20) and p-nitrophenyl-α-D-glucopyranosi... | Chem Biol Drug Des 87: 361-73 (2016) Article DOI: 10.1111/cbdd.12666 BindingDB Entry DOI: 10.7270/Q2HQ3XPS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta-glucuronidase (Bos taurus (Bovine)) | BDBM178133 (3-(6-Chloro-1H-imidazo[4,5-b]pyridin-2-yl)benzene-...) | KEGG UniProtKB/TrEMBL GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.93E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Universiti Teknologi MARA (UiTM), Puncak Alam Campus | Assay Description The protocol followed in this study was earlier reported [33,34]. β-Glucuronidase activity was evaluated by measuring the absorbance at 405 nm o... | Bioorg Chem 65: 48-56 (2016) Article DOI: 10.1016/j.bioorg.2016.01.007 BindingDB Entry DOI: 10.7270/Q2ZS2V8X | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta-glucuronidase (Bos taurus (Bovine)) | BDBM178131 (4-(6-Chloro-1H-imidazo[4,5-b]pyridin-2-yl)benzene-...) | KEGG UniProtKB/TrEMBL GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 3.01E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Universiti Teknologi MARA (UiTM), Puncak Alam Campus | Assay Description The protocol followed in this study was earlier reported [33,34]. β-Glucuronidase activity was evaluated by measuring the absorbance at 405 nm o... | Bioorg Chem 65: 48-56 (2016) Article DOI: 10.1016/j.bioorg.2016.01.007 BindingDB Entry DOI: 10.7270/Q2ZS2V8X | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Oligo-1,6-glucosidase IMA1 (Saccharomyces cerevisiae S288c (Baker's yeast)) | BDBM50431165 (2-(3-hydroxyphenyl)-4H-chromen-4-one (2) | CHEMBL1...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL MMDB PC cid PC sid PDB UniChem Similars | Article PubMed | n/a | n/a | 3.47E+4 | n/a | n/a | n/a | n/a | 6.8 | n/a |
Universiti Teknologi MARA | Assay Description The α-glucosidase inhibition assay had been carried out using baker¿s yeast a-glucosidase (EC 3.2.1.20) and p-nitrophenyl-α-D-glucopyranosi... | Chem Biol Drug Des 87: 361-73 (2016) Article DOI: 10.1111/cbdd.12666 BindingDB Entry DOI: 10.7270/Q2HQ3XPS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Oligo-1,6-glucosidase IMA1 (Saccharomyces cerevisiae S288c (Baker's yeast)) | BDBM178008 (4-((3-(4-oxo-4H-chromen-2-yl)phenoxy)methyl)benzon...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 3.47E+4 | n/a | n/a | n/a | n/a | 6.8 | n/a |
Universiti Teknologi MARA | Assay Description The α-glucosidase inhibition assay had been carried out using baker¿s yeast a-glucosidase (EC 3.2.1.20) and p-nitrophenyl-α-D-glucopyranosi... | Chem Biol Drug Des 87: 361-73 (2016) Article DOI: 10.1111/cbdd.12666 BindingDB Entry DOI: 10.7270/Q2HQ3XPS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Oligo-1,6-glucosidase IMA1 (Saccharomyces cerevisiae S288c (Baker's yeast)) | BDBM178009 (2-(3-((4-methoxybenzyl)oxy)phenyl)-4H-chromen-4-on...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 3.54E+4 | n/a | n/a | n/a | n/a | 6.8 | n/a |
Universiti Teknologi MARA | Assay Description The α-glucosidase inhibition assay had been carried out using baker¿s yeast a-glucosidase (EC 3.2.1.20) and p-nitrophenyl-α-D-glucopyranosi... | Chem Biol Drug Des 87: 361-73 (2016) Article DOI: 10.1111/cbdd.12666 BindingDB Entry DOI: 10.7270/Q2HQ3XPS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Oligo-1,6-glucosidase IMA1 (Saccharomyces cerevisiae S288c (Baker's yeast)) | BDBM178002 (2-(3-((4-nitrobenzyl)oxy)phenyl)-4H-chromen-4-one ...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 3.64E+4 | n/a | n/a | n/a | n/a | 6.8 | n/a |
Universiti Teknologi MARA | Assay Description The α-glucosidase inhibition assay had been carried out using baker¿s yeast a-glucosidase (EC 3.2.1.20) and p-nitrophenyl-α-D-glucopyranosi... | Chem Biol Drug Des 87: 361-73 (2016) Article DOI: 10.1111/cbdd.12666 BindingDB Entry DOI: 10.7270/Q2HQ3XPS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Oligo-1,6-glucosidase IMA1 (Saccharomyces cerevisiae S288c (Baker's yeast)) | BDBM23406 ((3R,4R,5S,6R)-5-{[(2R,3R,4R,5S,6R)-5-{[(2R,3R,4S,5...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase PC cid PC sid PDB UniChem Similars | Article PubMed | n/a | n/a | 3.83E+4 | n/a | n/a | n/a | n/a | 6.8 | n/a |
Universiti Teknologi MARA | Assay Description The α-glucosidase inhibition assay had been carried out using baker¿s yeast a-glucosidase (EC 3.2.1.20) and p-nitrophenyl-α-D-glucopyranosi... | Chem Biol Drug Des 87: 361-73 (2016) Article DOI: 10.1111/cbdd.12666 BindingDB Entry DOI: 10.7270/Q2HQ3XPS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Oligo-1,6-glucosidase IMA1 (Saccharomyces cerevisiae S288c (Baker's yeast)) | BDBM178012 (3-((3-(4-oxo-4H-chromen-2-yl)phenoxy)methyl)benzon...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 3.86E+4 | n/a | n/a | n/a | n/a | 6.8 | n/a |
Universiti Teknologi MARA | Assay Description The α-glucosidase inhibition assay had been carried out using baker¿s yeast a-glucosidase (EC 3.2.1.20) and p-nitrophenyl-α-D-glucopyranosi... | Chem Biol Drug Des 87: 361-73 (2016) Article DOI: 10.1111/cbdd.12666 BindingDB Entry DOI: 10.7270/Q2HQ3XPS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Oligo-1,6-glucosidase IMA1 (Saccharomyces cerevisiae S288c (Baker's yeast)) | BDBM178001 ((E)-1-(2-hydroxyphenyl)-3-(3-hydroxyphenyl)prop-2-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 4.47E+4 | n/a | n/a | n/a | n/a | 6.8 | n/a |
Universiti Teknologi MARA | Assay Description The α-glucosidase inhibition assay had been carried out using baker¿s yeast a-glucosidase (EC 3.2.1.20) and p-nitrophenyl-α-D-glucopyranosi... | Chem Biol Drug Des 87: 361-73 (2016) Article DOI: 10.1111/cbdd.12666 BindingDB Entry DOI: 10.7270/Q2HQ3XPS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta-glucuronidase (Bos taurus (Bovine)) | BDBM178134 (2-(6-Chloro-1H-imidazo[4,5-b]pyridin-2-yl)benzene-...) | KEGG UniProtKB/TrEMBL GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 4.61E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Universiti Teknologi MARA (UiTM), Puncak Alam Campus | Assay Description The protocol followed in this study was earlier reported [33,34]. β-Glucuronidase activity was evaluated by measuring the absorbance at 405 nm o... | Bioorg Chem 65: 48-56 (2016) Article DOI: 10.1016/j.bioorg.2016.01.007 BindingDB Entry DOI: 10.7270/Q2ZS2V8X | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta-glucuronidase (Bos taurus (Bovine)) | BDBM178139 (D-Saccharic acid 1,4-lactone) | KEGG UniProtKB/TrEMBL GoogleScholar AffyNet | Purchase KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 4.85E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Universiti Teknologi MARA (UiTM), Puncak Alam Campus | Assay Description The protocol followed in this study was earlier reported [33,34]. β-Glucuronidase activity was evaluated by measuring the absorbance at 405 nm o... | Bioorg Chem 65: 48-56 (2016) Article DOI: 10.1016/j.bioorg.2016.01.007 BindingDB Entry DOI: 10.7270/Q2ZS2V8X | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Oligo-1,6-glucosidase IMA1 (Saccharomyces cerevisiae S288c (Baker's yeast)) | BDBM178005 (2-(3-((4-(tert-butyl)benzyl)oxy)phenyl)-4H-chromen...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 4.95E+4 | n/a | n/a | n/a | n/a | 6.8 | n/a |
Universiti Teknologi MARA | Assay Description The α-glucosidase inhibition assay had been carried out using baker¿s yeast a-glucosidase (EC 3.2.1.20) and p-nitrophenyl-α-D-glucopyranosi... | Chem Biol Drug Des 87: 361-73 (2016) Article DOI: 10.1111/cbdd.12666 BindingDB Entry DOI: 10.7270/Q2HQ3XPS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta-glucuronidase (Bos taurus (Bovine)) | BDBM178132 (4-(6-Chloro-1H-imidazo[4,5-b]pyridin-2-yl)benzene-...) | KEGG UniProtKB/TrEMBL GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 4.96E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Universiti Teknologi MARA (UiTM), Puncak Alam Campus | Assay Description The protocol followed in this study was earlier reported [33,34]. β-Glucuronidase activity was evaluated by measuring the absorbance at 405 nm o... | Bioorg Chem 65: 48-56 (2016) Article DOI: 10.1016/j.bioorg.2016.01.007 BindingDB Entry DOI: 10.7270/Q2ZS2V8X | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta-glucuronidase (Bos taurus (Bovine)) | BDBM178138 (4-(6-Chloro-1H-imidazo[4,5-b]pyridin-2-yl)phenol (...) | KEGG UniProtKB/TrEMBL GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 5.26E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Universiti Teknologi MARA (UiTM), Puncak Alam Campus | Assay Description The protocol followed in this study was earlier reported [33,34]. β-Glucuronidase activity was evaluated by measuring the absorbance at 405 nm o... | Bioorg Chem 65: 48-56 (2016) Article DOI: 10.1016/j.bioorg.2016.01.007 BindingDB Entry DOI: 10.7270/Q2ZS2V8X | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Oligo-1,6-glucosidase IMA1 (Saccharomyces cerevisiae S288c (Baker's yeast)) | BDBM178003 (2-(3-(benzyloxy)phenyl)-4H-chromen-4-one (4)) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 5.97E+4 | n/a | n/a | n/a | n/a | 6.8 | n/a |
Universiti Teknologi MARA | Assay Description The α-glucosidase inhibition assay had been carried out using baker¿s yeast a-glucosidase (EC 3.2.1.20) and p-nitrophenyl-α-D-glucopyranosi... | Chem Biol Drug Des 87: 361-73 (2016) Article DOI: 10.1111/cbdd.12666 BindingDB Entry DOI: 10.7270/Q2HQ3XPS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta-glucuronidase (Bos taurus (Bovine)) | BDBM178135 (3-(6-Chloro-1H-imidazo[4,5-b]pyridin-2-yl)phenol (...) | KEGG UniProtKB/TrEMBL GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 6.81E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Universiti Teknologi MARA (UiTM), Puncak Alam Campus | Assay Description The protocol followed in this study was earlier reported [33,34]. β-Glucuronidase activity was evaluated by measuring the absorbance at 405 nm o... | Bioorg Chem 65: 48-56 (2016) Article DOI: 10.1016/j.bioorg.2016.01.007 BindingDB Entry DOI: 10.7270/Q2ZS2V8X | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Oligo-1,6-glucosidase IMA1 (Saccharomyces cerevisiae S288c (Baker's yeast)) | BDBM178011 (2-(3-((3-methylbenzyl)oxy)phenyl)-4H-chromen-4-one...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 8.87E+4 | n/a | n/a | n/a | n/a | 6.8 | n/a |
Universiti Teknologi MARA | Assay Description The α-glucosidase inhibition assay had been carried out using baker¿s yeast a-glucosidase (EC 3.2.1.20) and p-nitrophenyl-α-D-glucopyranosi... | Chem Biol Drug Des 87: 361-73 (2016) Article DOI: 10.1111/cbdd.12666 BindingDB Entry DOI: 10.7270/Q2HQ3XPS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta-glucuronidase (Bos taurus (Bovine)) | BDBM178137 (2-(6-Chloro-1H-imidazo[4,5-b]pyridin-2-yl)-5-metho...) | KEGG UniProtKB/TrEMBL GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.14E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Universiti Teknologi MARA (UiTM), Puncak Alam Campus | Assay Description The protocol followed in this study was earlier reported [33,34]. β-Glucuronidase activity was evaluated by measuring the absorbance at 405 nm o... | Bioorg Chem 65: 48-56 (2016) Article DOI: 10.1016/j.bioorg.2016.01.007 BindingDB Entry DOI: 10.7270/Q2ZS2V8X | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta-glucuronidase (Bos taurus (Bovine)) | BDBM178136 (2-(6-Chloro-1H-imidazo[4,5-b]pyridin-2-yl)-4-metho...) | KEGG UniProtKB/TrEMBL GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.29E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Universiti Teknologi MARA (UiTM), Puncak Alam Campus | Assay Description The protocol followed in this study was earlier reported [33,34]. β-Glucuronidase activity was evaluated by measuring the absorbance at 405 nm o... | Bioorg Chem 65: 48-56 (2016) Article DOI: 10.1016/j.bioorg.2016.01.007 BindingDB Entry DOI: 10.7270/Q2ZS2V8X | |||||||||||
More data for this Ligand-Target Pair |