Compile Data Set for Download or QSAR

Found 93 hits with Last Name = 'okawara' and Initial = 't'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
DNA topoisomerase 1 (Homo sapiens (Human))	BDBM50142519 (CHEMBL47027 | N-[2-(3,4,5-triihydroxy-benzoylamino...) Show SMILES Oc1cc(cc(O)c1O)C(=O)Nc1ccccc1NC(=O)c1cc(O)c(O)c(O)c1 Show InChI InChI=1S/C20H16N2O8/c23-13-5-9(6-14(24)17(13)27)19(29)21-11-3-1-2-4-12(11)22-20(30)10-7-15(25)18(28)16(26)8-10/h1-8,23-28H,(H,21,29)(H,22,30)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	400	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Kumamoto University Curated by ChEMBL					Assay Description Inhibition of relaxation activities of DNA topoisomerase I with respect to pBR322 DNA				Bioorg Med Chem Lett 14: 1669-72 (2004) Article DOI: 10.1016/j.bmcl.2004.01.060 BindingDB Entry DOI: 10.7270/Q2GX4B0X
					More data for this Ligand-Target Pair
DNA topoisomerase 2-alpha/2-beta (Homo sapiens (Human))	BDBM50142519 (CHEMBL47027 | N-[2-(3,4,5-triihydroxy-benzoylamino...) Show SMILES Oc1cc(cc(O)c1O)C(=O)Nc1ccccc1NC(=O)c1cc(O)c(O)c(O)c1 Show InChI InChI=1S/C20H16N2O8/c23-13-5-9(6-14(24)17(13)27)19(29)21-11-3-1-2-4-12(11)22-20(30)10-7-15(25)18(28)16(26)8-10/h1-8,23-28H,(H,21,29)(H,22,30)	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	7.41E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Kumamoto University Curated by ChEMBL					Assay Description Inhibition of relaxation activities of DNA topoisomerase II with respect to pBR322 DNA				Bioorg Med Chem Lett 14: 1669-72 (2004) Article DOI: 10.1016/j.bmcl.2004.01.060 BindingDB Entry DOI: 10.7270/Q2GX4B0X
					More data for this Ligand-Target Pair
DNA topoisomerase 2-alpha/2-beta (Homo sapiens (Human))	BDBM50142519 (CHEMBL47027 | N-[2-(3,4,5-triihydroxy-benzoylamino...) Show SMILES Oc1cc(cc(O)c1O)C(=O)Nc1ccccc1NC(=O)c1cc(O)c(O)c(O)c1 Show InChI InChI=1S/C20H16N2O8/c23-13-5-9(6-14(24)17(13)27)19(29)21-11-3-1-2-4-12(11)22-20(30)10-7-15(25)18(28)16(26)8-10/h1-8,23-28H,(H,21,29)(H,22,30)	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
Kumamoto University Curated by ChEMBL					Assay Description Inhibitory concentration against relaxation activity of DNA topoisomerase II by detecting the conversion of supercoiled pBR322 DNA to its relaxed for...				Bioorg Med Chem Lett 14: 1669-72 (2004) Article DOI: 10.1016/j.bmcl.2004.01.060 BindingDB Entry DOI: 10.7270/Q2GX4B0X
					More data for this Ligand-Target Pair
Poly(ADP-ribose) glycohydrolase (Rattus norvegicus)	BDBM50350107 (CHEMBL1230692) Show SMILES Nc1ncnc2n(cnc12)[C@@H]1O[C@H](CO[P@@](O)(=O)O[P@](O)(=O)OC[C@H]2NC[C@H](O)[C@@H]2O)[C@@H](O)[C@H]1O |r| Show InChI InChI=1S/C15H24N6O12P2/c16-13-9-14(19-4-18-13)21(5-20-9)15-12(25)11(24)8(32-15)3-31-35(28,29)33-34(26,27)30-2-6-10(23)7(22)1-17-6/h4-8,10-12,15,17,22-25H,1-3H2,(H,26,27)(H,28,29)(H2,16,18,19)/t6-,7+,8-,10-,11-,12-,15-/m1/s1	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL KEGG MMDB PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
Kumamoto Health Science University Curated by ChEMBL					Assay Description Inhibition of rat testis GST-tagged PARG catalytic activity after 30 mins using [32P]poly(ADP-ribose) by radioassay				Bioorg Med Chem Lett 24: 3802-6 (2014) Article DOI: 10.1016/j.bmcl.2014.06.065 BindingDB Entry DOI: 10.7270/Q2348N18
					More data for this Ligand-Target Pair				3D Structure (crystal)
DNA topoisomerase 2-alpha/2-beta (Homo sapiens (Human))	BDBM50142517 (CHEMBL47885 | N-[4-(3,4,5-triihydroxy-benzoylamino...) Show SMILES Oc1cc(cc(O)c1O)C(=O)Nc1ccc(NC(=O)c2cc(O)c(O)c(O)c2)cc1 Show InChI InChI=1S/C20H16N2O8/c23-13-5-9(6-14(24)17(13)27)19(29)21-11-1-2-12(4-3-11)22-20(30)10-7-15(25)18(28)16(26)8-10/h1-8,23-28H,(H,21,29)(H,22,30)	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	150	n/a	n/a	n/a	n/a	n/a	n/a
Kumamoto University Curated by ChEMBL					Assay Description Inhibitory concentration against relaxation activity of DNA topoisomerase II by detecting the conversion of supercoiled pBR322 DNA to its relaxed for...				Bioorg Med Chem Lett 14: 1669-72 (2004) Article DOI: 10.1016/j.bmcl.2004.01.060 BindingDB Entry DOI: 10.7270/Q2GX4B0X
					More data for this Ligand-Target Pair
DNA topoisomerase 2-alpha/2-beta (Homo sapiens (Human))	BDBM50142507 (CHEMBL47526 | N-[3-(3,4,5-triihydroxy-benzoylamino...) Show SMILES Oc1cc(cc(O)c1O)C(=O)Nc1cccc(NC(=O)c2cc(O)c(O)c(O)c2)c1 Show InChI InChI=1S/C20H16N2O8/c23-13-4-9(5-14(24)17(13)27)19(29)21-11-2-1-3-12(8-11)22-20(30)10-6-15(25)18(28)16(26)7-10/h1-8,23-28H,(H,21,29)(H,22,30)	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	220	n/a	n/a	n/a	n/a	n/a	n/a
Kumamoto University Curated by ChEMBL					Assay Description Inhibitory concentration against relaxation activity of DNA topoisomerase II by detecting the conversion of supercoiled pBR322 DNA to its relaxed for...				Bioorg Med Chem Lett 14: 1669-72 (2004) Article DOI: 10.1016/j.bmcl.2004.01.060 BindingDB Entry DOI: 10.7270/Q2GX4B0X
					More data for this Ligand-Target Pair
DNA topoisomerase 1 (Homo sapiens (Human))	BDBM50142519 (CHEMBL47027 | N-[2-(3,4,5-triihydroxy-benzoylamino...) Show SMILES Oc1cc(cc(O)c1O)C(=O)Nc1ccccc1NC(=O)c1cc(O)c(O)c(O)c1 Show InChI InChI=1S/C20H16N2O8/c23-13-5-9(6-14(24)17(13)27)19(29)21-11-3-1-2-4-12(11)22-20(30)10-7-15(25)18(28)16(26)8-10/h1-8,23-28H,(H,21,29)(H,22,30)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	900	n/a	n/a	n/a	n/a	n/a	n/a
Kumamoto University Curated by ChEMBL					Assay Description Inhibitory concentration against relaxation activity of DNA topoisomerase I by detecting the conversion of supercoiled pBR322 DNA to its relaxed form				Bioorg Med Chem Lett 14: 1669-72 (2004) Article DOI: 10.1016/j.bmcl.2004.01.060 BindingDB Entry DOI: 10.7270/Q2GX4B0X
					More data for this Ligand-Target Pair
Poly(ADP-ribose) glycohydrolase (Rattus norvegicus)	BDBM50052832 (CHEMBL3318753) Show SMILES OC[C@H]1OC(O)[C@H](O)[C@@H](OC(=O)c2cc(O)c(O)c(O)c2)[C@@H]1O |r| Show InChI InChI=1S/C13H16O10/c14-3-7-9(18)11(10(19)13(21)22-7)23-12(20)4-1-5(15)8(17)6(16)2-4/h1-2,7,9-11,13-19,21H,3H2/t7-,9-,10-,11+,13?/m1/s1	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	950	n/a	n/a	n/a	n/a	n/a	n/a
Kumamoto Health Science University Curated by ChEMBL					Assay Description Inhibition of rat testis GST-tagged PARG catalytic activity after 30 mins using [32P]poly(ADP-ribose) by radioassay				Bioorg Med Chem Lett 24: 3802-6 (2014) Article DOI: 10.1016/j.bmcl.2014.06.065 BindingDB Entry DOI: 10.7270/Q2348N18
					More data for this Ligand-Target Pair
Poly(ADP-ribose) glycohydrolase (Rattus norvegicus)	BDBM50053036 (CHEMBL3318737) Show SMILES Oc1ccc(\C=N\NC(=O)c2ccc(cc2)C(=O)N\N=C\c2ccc(O)c(O)c2O)c(O)c1O Show InChI InChI=1S/C22H18N4O8/c27-15-7-5-13(17(29)19(15)31)9-23-25-21(33)11-1-2-12(4-3-11)22(34)26-24-10-14-6-8-16(28)20(32)18(14)30/h1-10,27-32H,(H,25,33)(H,26,34)/b23-9+,24-10+	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Kumamoto Health Science University Curated by ChEMBL					Assay Description Inhibition of rat testis GST-tagged PARG catalytic activity after 30 mins using [32P]poly(ADP-ribose) by radioassay				Bioorg Med Chem Lett 24: 3802-6 (2014) Article DOI: 10.1016/j.bmcl.2014.06.065 BindingDB Entry DOI: 10.7270/Q2348N18
					More data for this Ligand-Target Pair
DNA topoisomerase 1 (Homo sapiens (Human))	BDBM50142517 (CHEMBL47885 | N-[4-(3,4,5-triihydroxy-benzoylamino...) Show SMILES Oc1cc(cc(O)c1O)C(=O)Nc1ccc(NC(=O)c2cc(O)c(O)c(O)c2)cc1 Show InChI InChI=1S/C20H16N2O8/c23-13-5-9(6-14(24)17(13)27)19(29)21-11-1-2-12(4-3-11)22-20(30)10-7-15(25)18(28)16(26)8-10/h1-8,23-28H,(H,21,29)(H,22,30)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
Kumamoto University Curated by ChEMBL					Assay Description Inhibitory concentration against relaxation activity of DNA topoisomerase I by detecting the conversion of supercoiled pBR322 DNA to its relaxed form				Bioorg Med Chem Lett 14: 1669-72 (2004) Article DOI: 10.1016/j.bmcl.2004.01.060 BindingDB Entry DOI: 10.7270/Q2GX4B0X
					More data for this Ligand-Target Pair
Poly(ADP-ribose) glycohydrolase (Rattus norvegicus)	BDBM50052838 (CHEMBL3318748) Show SMILES Oc1ccc(\C=N\NC(=O)CC(=O)N\N=C\c2ccc(O)c(O)c2O)c(O)c1O Show InChI InChI=1S/C17H16N4O8/c22-10-3-1-8(14(26)16(10)28)6-18-20-12(24)5-13(25)21-19-7-9-2-4-11(23)17(29)15(9)27/h1-4,6-7,22-23,26-29H,5H2,(H,20,24)(H,21,25)/b18-6+,19-7+	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
Kumamoto Health Science University Curated by ChEMBL					Assay Description Inhibition of rat testis GST-tagged PARG catalytic activity after 30 mins using [32P]poly(ADP-ribose) by radioassay				Bioorg Med Chem Lett 24: 3802-6 (2014) Article DOI: 10.1016/j.bmcl.2014.06.065 BindingDB Entry DOI: 10.7270/Q2348N18
					More data for this Ligand-Target Pair
DNA topoisomerase 1 (Homo sapiens (Human))	BDBM50142507 (CHEMBL47526 | N-[3-(3,4,5-triihydroxy-benzoylamino...) Show SMILES Oc1cc(cc(O)c1O)C(=O)Nc1cccc(NC(=O)c2cc(O)c(O)c(O)c2)c1 Show InChI InChI=1S/C20H16N2O8/c23-13-4-9(5-14(24)17(13)27)19(29)21-11-2-1-3-12(8-11)22-20(30)10-6-15(25)18(28)16(26)7-10/h1-8,23-28H,(H,21,29)(H,22,30)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
Kumamoto University Curated by ChEMBL					Assay Description Inhibitory concentration against relaxation activity of DNA topoisomerase I by detecting the conversion of supercoiled pBR322 DNA to its relaxed form				Bioorg Med Chem Lett 14: 1669-72 (2004) Article DOI: 10.1016/j.bmcl.2004.01.060 BindingDB Entry DOI: 10.7270/Q2GX4B0X
					More data for this Ligand-Target Pair
Poly(ADP-ribose) glycohydrolase (Rattus norvegicus)	BDBM50053035 (CHEMBL3318738) Show SMILES Oc1cc(\C=N\NC(=O)c2ccc(cc2)C(=O)N\N=C\c2cc(O)c(O)c(O)c2)cc(O)c1O Show InChI InChI=1S/C22H18N4O8/c27-15-5-11(6-16(28)19(15)31)9-23-25-21(33)13-1-2-14(4-3-13)22(34)26-24-10-12-7-17(29)20(32)18(30)8-12/h1-10,27-32H,(H,25,33)(H,26,34)/b23-9+,24-10+	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Kumamoto Health Science University Curated by ChEMBL					Assay Description Inhibition of rat testis GST-tagged PARG catalytic activity after 30 mins using [32P]poly(ADP-ribose) by radioassay				Bioorg Med Chem Lett 24: 3802-6 (2014) Article DOI: 10.1016/j.bmcl.2014.06.065 BindingDB Entry DOI: 10.7270/Q2348N18
					More data for this Ligand-Target Pair
DNA topoisomerase 1 (Homo sapiens (Human))	BDBM50142526 (CHEMBL44765 | N-[4-(3,4-dihydroxy-benzoylamino)-ph...) Show SMILES Oc1ccc(cc1O)C(=O)Nc1ccc(NC(=O)c2ccc(O)c(O)c2)cc1 Show InChI InChI=1S/C20H16N2O6/c23-15-7-1-11(9-17(15)25)19(27)21-13-3-5-14(6-4-13)22-20(28)12-2-8-16(24)18(26)10-12/h1-10,23-26H,(H,21,27)(H,22,28)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
Kumamoto University Curated by ChEMBL					Assay Description Inhibitory concentration against relaxation activity of DNA topoisomerase I by detecting the conversion of supercoiled pBR322 DNA to its relaxed form				Bioorg Med Chem Lett 14: 1669-72 (2004) Article DOI: 10.1016/j.bmcl.2004.01.060 BindingDB Entry DOI: 10.7270/Q2GX4B0X
					More data for this Ligand-Target Pair
Poly(ADP-ribose) glycohydrolase (Rattus norvegicus)	BDBM50052839 (CHEMBL3318747) Show SMILES Oc1cc(\C=N\NC(=O)C(=O)N\N=C\c2cc(O)c(O)c(O)c2)cc(O)c1O Show InChI InChI=1S/C16H14N4O8/c21-9-1-7(2-10(22)13(9)25)5-17-19-15(27)16(28)20-18-6-8-3-11(23)14(26)12(24)4-8/h1-6,21-26H,(H,19,27)(H,20,28)/b17-5+,18-6+	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
Kumamoto Health Science University Curated by ChEMBL					Assay Description Inhibition of rat testis GST-tagged PARG catalytic activity after 30 mins using [32P]poly(ADP-ribose) by radioassay				Bioorg Med Chem Lett 24: 3802-6 (2014) Article DOI: 10.1016/j.bmcl.2014.06.065 BindingDB Entry DOI: 10.7270/Q2348N18
					More data for this Ligand-Target Pair
Poly(ADP-ribose) glycohydrolase (Rattus norvegicus)	BDBM50052831 (CHEMBL3318754) Show SMILES OC(=O)CCN1C(=S)S\C(C1=O)=C1/N(Cc2c(Cl)cccc2Cl)c2ccc(Br)cc2C1=O Show InChI InChI=1S/C21H13BrCl2N2O4S2/c22-10-4-5-15-11(8-10)18(29)17(26(15)9-12-13(23)2-1-3-14(12)24)19-20(30)25(21(31)32-19)7-6-16(27)28/h1-5,8H,6-7,9H2,(H,27,28)/b19-17-	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
Kumamoto Health Science University Curated by ChEMBL					Assay Description Inhibition of rat testis GST-tagged PARG catalytic activity after 30 mins using [32P]poly(ADP-ribose) by radioassay				Bioorg Med Chem Lett 24: 3802-6 (2014) Article DOI: 10.1016/j.bmcl.2014.06.065 BindingDB Entry DOI: 10.7270/Q2348N18
					More data for this Ligand-Target Pair
DNA topoisomerase 1 (Homo sapiens (Human))	BDBM50410165 (CHEMBL372661) Show SMILES Oc1ccc2OC(=O)\C(=C\c3cc(O)c(O)c(O)c3)c2c1 Show InChI InChI=1S/C15H10O6/c16-8-1-2-13-9(6-8)10(15(20)21-13)3-7-4-11(17)14(19)12(18)5-7/h1-6,16-19H/b10-3+	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Kumamoto University Curated by ChEMBL					Assay Description Inhibitory concentration against DNA topoisomerase I activity				Bioorg Med Chem Lett 15: 2065-8 (2005) Article DOI: 10.1016/j.bmcl.2005.02.052 BindingDB Entry DOI: 10.7270/Q2WH2R6D
					More data for this Ligand-Target Pair
Poly(ADP-ribose) glycohydrolase (Rattus norvegicus)	BDBM50052840 (CHEMBL3318746) Show SMILES Oc1ccc(\C=N\NC(=O)C(=O)N\N=C\c2ccc(O)c(O)c2O)c(O)c1O Show InChI InChI=1S/C16H14N4O8/c21-9-3-1-7(11(23)13(9)25)5-17-19-15(27)16(28)20-18-6-8-2-4-10(22)14(26)12(8)24/h1-6,21-26H,(H,19,27)(H,20,28)/b17-5+,18-6+	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	3.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Kumamoto Health Science University Curated by ChEMBL					Assay Description Inhibition of rat testis GST-tagged PARG catalytic activity after 30 mins using [32P]poly(ADP-ribose) by radioassay				Bioorg Med Chem Lett 24: 3802-6 (2014) Article DOI: 10.1016/j.bmcl.2014.06.065 BindingDB Entry DOI: 10.7270/Q2348N18
					More data for this Ligand-Target Pair
Poly(ADP-ribose) glycohydrolase (Rattus norvegicus)	BDBM50052843 (CHEMBL3318743) Show SMILES Oc1ccc(\C=N\NC(=O)c2cccc(c2)C(=O)N\N=C\c2ccc(O)c(O)c2O)c(O)c1O Show InChI InChI=1S/C22H18N4O8/c27-15-6-4-13(17(29)19(15)31)9-23-25-21(33)11-2-1-3-12(8-11)22(34)26-24-10-14-5-7-16(28)20(32)18(14)30/h1-10,27-32H,(H,25,33)(H,26,34)/b23-9+,24-10+	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Kumamoto Health Science University Curated by ChEMBL					Assay Description Inhibition of rat testis GST-tagged PARG catalytic activity after 30 mins using [32P]poly(ADP-ribose) by radioassay				Bioorg Med Chem Lett 24: 3802-6 (2014) Article DOI: 10.1016/j.bmcl.2014.06.065 BindingDB Entry DOI: 10.7270/Q2348N18
					More data for this Ligand-Target Pair
Poly(ADP-ribose) glycohydrolase (Rattus norvegicus)	BDBM50052842 (CHEMBL3318744) Show SMILES Oc1cc(\C=N\NC(=O)c2cccc(c2)C(=O)N\N=C\c2cc(O)c(O)c(O)c2)cc(O)c1O Show InChI InChI=1S/C22H18N4O8/c27-15-4-11(5-16(28)19(15)31)9-23-25-21(33)13-2-1-3-14(8-13)22(34)26-24-10-12-6-17(29)20(32)18(30)7-12/h1-10,27-32H,(H,25,33)(H,26,34)/b23-9+,24-10+	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Kumamoto Health Science University Curated by ChEMBL					Assay Description Inhibition of rat testis GST-tagged PARG catalytic activity after 30 mins using [32P]poly(ADP-ribose) by radioassay				Bioorg Med Chem Lett 24: 3802-6 (2014) Article DOI: 10.1016/j.bmcl.2014.06.065 BindingDB Entry DOI: 10.7270/Q2348N18
					More data for this Ligand-Target Pair
DNA topoisomerase 1 (Homo sapiens (Human))	BDBM50410153 (CHEMBL197216) Show SMILES Oc1cc(\C=C2\C(=O)Oc3ccccc23)cc(O)c1O Show InChI InChI=1S/C15H10O5/c16-11-6-8(7-12(17)14(11)18)5-10-9-3-1-2-4-13(9)20-15(10)19/h1-7,16-18H/b10-5+	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Kumamoto University Curated by ChEMBL					Assay Description Inhibitory concentration against DNA topoisomerase I activity				Bioorg Med Chem Lett 15: 2065-8 (2005) Article DOI: 10.1016/j.bmcl.2005.02.052 BindingDB Entry DOI: 10.7270/Q2WH2R6D
					More data for this Ligand-Target Pair
DNA topoisomerase 1 (Homo sapiens (Human))	BDBM50142529 (Acetic acid 2,3-diacetoxy-5-[2-(3,4,5-triacetoxy-b...) Show SMILES CC(=O)Oc1cc(cc(OC(C)=O)c1OC(C)=O)C(=O)Nc1ccccc1NC(=O)c1cc(OC(C)=O)c(OC(C)=O)c(OC(C)=O)c1 Show InChI InChI=1S/C32H28N2O14/c1-15(35)43-25-11-21(12-26(44-16(2)36)29(25)47-19(5)39)31(41)33-23-9-7-8-10-24(23)34-32(42)22-13-27(45-17(3)37)30(48-20(6)40)28(14-22)46-18(4)38/h7-14H,1-6H3,(H,33,41)(H,34,42)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
Kumamoto University Curated by ChEMBL					Assay Description Inhibitory concentration against relaxation activity of DNA topoisomerase I by detecting the conversion of supercoiled pBR322 DNA to its relaxed form				Bioorg Med Chem Lett 14: 1669-72 (2004) Article DOI: 10.1016/j.bmcl.2004.01.060 BindingDB Entry DOI: 10.7270/Q2GX4B0X
					More data for this Ligand-Target Pair
DNA topoisomerase 1 (Homo sapiens (Human))	BDBM50410158 (CHEMBL195195) Show SMILES Oc1ccc2OC(=O)\C(=C\c3ccc(O)c(O)c3)c2c1 Show InChI InChI=1S/C15H10O5/c16-9-2-4-14-10(7-9)11(15(19)20-14)5-8-1-3-12(17)13(18)6-8/h1-7,16-18H/b11-5+	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Kumamoto University Curated by ChEMBL					Assay Description Inhibitory concentration against DNA topoisomerase I activity				Bioorg Med Chem Lett 15: 2065-8 (2005) Article DOI: 10.1016/j.bmcl.2005.02.052 BindingDB Entry DOI: 10.7270/Q2WH2R6D
					More data for this Ligand-Target Pair
DNA topoisomerase 1 (Homo sapiens (Human))	BDBM50142509 (CHEMBL44441 | N-[2-(3,4-dihydroxy-benzoylamino)-ph...) Show SMILES Oc1ccc(cc1O)C(=O)Nc1ccccc1NC(=O)c1ccc(O)c(O)c1 Show InChI InChI=1S/C20H16N2O6/c23-15-7-5-11(9-17(15)25)19(27)21-13-3-1-2-4-14(13)22-20(28)12-6-8-16(24)18(26)10-12/h1-10,23-26H,(H,21,27)(H,22,28)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
Kumamoto University Curated by ChEMBL					Assay Description Inhibitory concentration against relaxation activity of DNA topoisomerase I by detecting the conversion of supercoiled pBR322 DNA to its relaxed form				Bioorg Med Chem Lett 14: 1669-72 (2004) Article DOI: 10.1016/j.bmcl.2004.01.060 BindingDB Entry DOI: 10.7270/Q2GX4B0X
					More data for this Ligand-Target Pair
DNA topoisomerase 1 (Homo sapiens (Human))	BDBM50142528 (CHEMBL296351 | N-Benzothiazol-2-yl-3,4,5-trihydrox...) Show SMILES Oc1cc(cc(O)c1O)C(=O)Nc1nc2ccccc2s1 Show InChI InChI=1S/C14H10N2O4S/c17-9-5-7(6-10(18)12(9)19)13(20)16-14-15-8-3-1-2-4-11(8)21-14/h1-6,17-19H,(H,15,16,20)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Kumamoto University Curated by ChEMBL					Assay Description Inhibitory concentration against relaxation activity of DNA topoisomerase I by detecting the conversion of supercoiled pBR322 DNA to its relaxed form				Bioorg Med Chem Lett 14: 1669-72 (2004) Article DOI: 10.1016/j.bmcl.2004.01.060 BindingDB Entry DOI: 10.7270/Q2GX4B0X
					More data for this Ligand-Target Pair
Poly(ADP-ribose) glycohydrolase (Rattus norvegicus)	BDBM50052835 (CHEMBL3318751) Show SMILES Oc1cc(\C=N\NC(=O)CCC(=O)N\N=C\c2cc(O)c(O)c(O)c2)cc(O)c1O Show InChI InChI=1S/C18H18N4O8/c23-11-3-9(4-12(24)17(11)29)7-19-21-15(27)1-2-16(28)22-20-8-10-5-13(25)18(30)14(26)6-10/h3-8,23-26,29-30H,1-2H2,(H,21,27)(H,22,28)/b19-7+,20-8+	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Kumamoto Health Science University Curated by ChEMBL					Assay Description Inhibition of rat testis GST-tagged PARG catalytic activity after 30 mins using [32P]poly(ADP-ribose) by radioassay				Bioorg Med Chem Lett 24: 3802-6 (2014) Article DOI: 10.1016/j.bmcl.2014.06.065 BindingDB Entry DOI: 10.7270/Q2348N18
					More data for this Ligand-Target Pair
DNA topoisomerase 1 (Homo sapiens (Human))	BDBM50142514 (Acetic acid 2,3-diacetoxy-5-[4-(3,4,5-triacetoxy-b...) Show SMILES CC(=O)Oc1cc(cc(OC(C)=O)c1OC(C)=O)C(=O)Nc1ccc(NC(=O)c2cc(OC(C)=O)c(OC(C)=O)c(OC(C)=O)c2)cc1 Show InChI InChI=1S/C32H28N2O14/c1-15(35)43-25-11-21(12-26(44-16(2)36)29(25)47-19(5)39)31(41)33-23-7-9-24(10-8-23)34-32(42)22-13-27(45-17(3)37)30(48-20(6)40)28(14-22)46-18(4)38/h7-14H,1-6H3,(H,33,41)(H,34,42)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
Kumamoto University Curated by ChEMBL					Assay Description Inhibitory concentration against relaxation activity of DNA topoisomerase I by detecting the conversion of supercoiled pBR322 DNA to its relaxed form				Bioorg Med Chem Lett 14: 1669-72 (2004) Article DOI: 10.1016/j.bmcl.2004.01.060 BindingDB Entry DOI: 10.7270/Q2GX4B0X
					More data for this Ligand-Target Pair
Poly(ADP-ribose) glycohydrolase (Rattus norvegicus)	BDBM50052836 (CHEMBL3318750) Show SMILES Oc1ccc(\C=N\NC(=O)CCC(=O)N\N=C\c2ccc(O)c(O)c2O)c(O)c1O Show InChI InChI=1S/C18H18N4O8/c23-11-3-1-9(15(27)17(11)29)7-19-21-13(25)5-6-14(26)22-20-8-10-2-4-12(24)18(30)16(10)28/h1-4,7-8,23-24,27-30H,5-6H2,(H,21,25)(H,22,26)/b19-7+,20-8+	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
Kumamoto Health Science University Curated by ChEMBL					Assay Description Inhibition of rat testis GST-tagged PARG catalytic activity after 30 mins using [32P]poly(ADP-ribose) by radioassay				Bioorg Med Chem Lett 24: 3802-6 (2014) Article DOI: 10.1016/j.bmcl.2014.06.065 BindingDB Entry DOI: 10.7270/Q2348N18
					More data for this Ligand-Target Pair
Poly(ADP-ribose) glycohydrolase (Rattus norvegicus)	BDBM50053034 (CHEMBL3318739) Show SMILES Oc1cc(O)c(\C=N\NC(=O)c2ccc(cc2)C(=O)N\N=C\c2c(O)cc(O)cc2O)c(O)c1 Show InChI InChI=1S/C22H18N4O8/c27-13-5-17(29)15(18(30)6-13)9-23-25-21(33)11-1-2-12(4-3-11)22(34)26-24-10-16-19(31)7-14(28)8-20(16)32/h1-10,27-32H,(H,25,33)(H,26,34)/b23-9+,24-10+	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
Kumamoto Health Science University Curated by ChEMBL					Assay Description Inhibition of rat testis GST-tagged PARG catalytic activity after 30 mins using [32P]poly(ADP-ribose) by radioassay				Bioorg Med Chem Lett 24: 3802-6 (2014) Article DOI: 10.1016/j.bmcl.2014.06.065 BindingDB Entry DOI: 10.7270/Q2348N18
					More data for this Ligand-Target Pair
DNA topoisomerase 1 (Homo sapiens (Human))	BDBM50142523 (CHEMBL297255 | N-[3-(3,4-dihydroxy-benzoylamino)-p...) Show SMILES Oc1ccc(cc1O)C(=O)Nc1cccc(NC(=O)c2ccc(O)c(O)c2)c1 Show InChI InChI=1S/C20H16N2O6/c23-15-6-4-11(8-17(15)25)19(27)21-13-2-1-3-14(10-13)22-20(28)12-5-7-16(24)18(26)9-12/h1-10,23-26H,(H,21,27)(H,22,28)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Kumamoto University Curated by ChEMBL					Assay Description Inhibitory concentration against relaxation activity of DNA topoisomerase I by detecting the conversion of supercoiled pBR322 DNA to its relaxed form				Bioorg Med Chem Lett 14: 1669-72 (2004) Article DOI: 10.1016/j.bmcl.2004.01.060 BindingDB Entry DOI: 10.7270/Q2GX4B0X
					More data for this Ligand-Target Pair
DNA topoisomerase 1 (Homo sapiens (Human))	BDBM50142510 (Acetic acid 2,3-diacetoxy-5-[3-(3,4,5-triacetoxy-b...) Show SMILES CC(=O)Oc1cc(cc(OC(C)=O)c1OC(C)=O)C(=O)Nc1cccc(NC(=O)c2cc(OC(C)=O)c(OC(C)=O)c(OC(C)=O)c2)c1 Show InChI InChI=1S/C32H28N2O14/c1-15(35)43-25-10-21(11-26(44-16(2)36)29(25)47-19(5)39)31(41)33-23-8-7-9-24(14-23)34-32(42)22-12-27(45-17(3)37)30(48-20(6)40)28(13-22)46-18(4)38/h7-14H,1-6H3,(H,33,41)(H,34,42)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.12E+4	n/a	n/a	n/a	n/a	n/a	n/a
Kumamoto University Curated by ChEMBL					Assay Description Inhibitory concentration against relaxation activity of DNA topoisomerase I by detecting the conversion of supercoiled pBR322 DNA to its relaxed form				Bioorg Med Chem Lett 14: 1669-72 (2004) Article DOI: 10.1016/j.bmcl.2004.01.060 BindingDB Entry DOI: 10.7270/Q2GX4B0X
					More data for this Ligand-Target Pair
Poly(ADP-ribose) glycohydrolase (Rattus norvegicus)	BDBM50052834 (CHEMBL3317464) Show SMILES Oc1ccc(\C=N\NC(=O)CCCC(=O)N\N=C\c2ccc(O)c(O)c2O)c(O)c1O Show InChI InChI=1S/C19H20N4O8/c24-12-6-4-10(16(28)18(12)30)8-20-22-14(26)2-1-3-15(27)23-21-9-11-5-7-13(25)19(31)17(11)29/h4-9,24-25,28-31H,1-3H2,(H,22,26)(H,23,27)/b20-8+,21-9+	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.39E+4	n/a	n/a	n/a	n/a	n/a	n/a
Kumamoto Health Science University Curated by ChEMBL					Assay Description Inhibition of rat testis GST-tagged PARG catalytic activity after 30 mins using [32P]poly(ADP-ribose) by radioassay				Bioorg Med Chem Lett 24: 3802-6 (2014) Article DOI: 10.1016/j.bmcl.2014.06.065 BindingDB Entry DOI: 10.7270/Q2348N18
					More data for this Ligand-Target Pair
Poly(ADP-ribose) glycohydrolase (Rattus norvegicus)	BDBM50053033 (CHEMBL3318740) Show SMILES Oc1cccc(\C=N\NC(=O)c2cccc(c2)C(=O)N\N=C\c2cccc(O)c2O)c1O Show InChI InChI=1S/C22H18N4O6/c27-17-8-2-6-15(19(17)29)11-23-25-21(31)13-4-1-5-14(10-13)22(32)26-24-12-16-7-3-9-18(28)20(16)30/h1-12,27-30H,(H,25,31)(H,26,32)/b23-11+,24-12+	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.48E+4	n/a	n/a	n/a	n/a	n/a	n/a
Kumamoto Health Science University Curated by ChEMBL					Assay Description Inhibition of rat testis GST-tagged PARG catalytic activity after 30 mins using [32P]poly(ADP-ribose) by radioassay				Bioorg Med Chem Lett 24: 3802-6 (2014) Article DOI: 10.1016/j.bmcl.2014.06.065 BindingDB Entry DOI: 10.7270/Q2348N18
					More data for this Ligand-Target Pair
Poly(ADP-ribose) glycohydrolase (Rattus norvegicus)	BDBM50052837 (CHEMBL3318749) Show SMILES Oc1cc(\C=N\NC(=O)CC(=O)N\N=C\c2cc(O)c(O)c(O)c2)cc(O)c1O Show InChI InChI=1S/C17H16N4O8/c22-10-1-8(2-11(23)16(10)28)6-18-20-14(26)5-15(27)21-19-7-9-3-12(24)17(29)13(25)4-9/h1-4,6-7,22-25,28-29H,5H2,(H,20,26)(H,21,27)/b18-6+,19-7+	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.54E+4	n/a	n/a	n/a	n/a	n/a	n/a
Kumamoto Health Science University Curated by ChEMBL					Assay Description Inhibition of rat testis GST-tagged PARG catalytic activity after 30 mins using [32P]poly(ADP-ribose) by radioassay				Bioorg Med Chem Lett 24: 3802-6 (2014) Article DOI: 10.1016/j.bmcl.2014.06.065 BindingDB Entry DOI: 10.7270/Q2348N18
					More data for this Ligand-Target Pair
DNA topoisomerase 1 (Homo sapiens (Human))	BDBM50142515 (CHEMBL44747 | N-Benzothiazol-2-yl-3,4-dihydroxy-be...) Show SMILES Oc1ccc(cc1O)C(=O)Nc1nc2ccccc2s1 Show InChI InChI=1S/C14H10N2O3S/c17-10-6-5-8(7-11(10)18)13(19)16-14-15-9-3-1-2-4-12(9)20-14/h1-7,17-18H,(H,15,16,19)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.69E+4	n/a	n/a	n/a	n/a	n/a	n/a
Kumamoto University Curated by ChEMBL					Assay Description Inhibitory concentration against relaxation activity of DNA topoisomerase I by detecting the conversion of supercoiled pBR322 DNA to its relaxed form				Bioorg Med Chem Lett 14: 1669-72 (2004) Article DOI: 10.1016/j.bmcl.2004.01.060 BindingDB Entry DOI: 10.7270/Q2GX4B0X
					More data for this Ligand-Target Pair
Poly(ADP-ribose) glycohydrolase (Rattus norvegicus)	BDBM50052841 (CHEMBL3318745) Show SMILES Oc1cc(O)c(\C=N\NC(=O)c2cccc(c2)C(=O)N\N=C\c2c(O)cc(O)cc2O)c(O)c1 Show InChI InChI=1S/C22H18N4O8/c27-13-5-17(29)15(18(30)6-13)9-23-25-21(33)11-2-1-3-12(4-11)22(34)26-24-10-16-19(31)7-14(28)8-20(16)32/h1-10,27-32H,(H,25,33)(H,26,34)/b23-9+,24-10+	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.88E+4	n/a	n/a	n/a	n/a	n/a	n/a
Kumamoto Health Science University Curated by ChEMBL					Assay Description Inhibition of rat testis GST-tagged PARG catalytic activity after 30 mins using [32P]poly(ADP-ribose) by radioassay				Bioorg Med Chem Lett 24: 3802-6 (2014) Article DOI: 10.1016/j.bmcl.2014.06.065 BindingDB Entry DOI: 10.7270/Q2348N18
					More data for this Ligand-Target Pair
Poly(ADP-ribose) glycohydrolase (Rattus norvegicus)	BDBM50052844 (CHEMBL3318742) Show SMILES Oc1ccc(\C=N\NC(=O)c2cccc(c2)C(=O)N\N=C\c2ccc(O)c(O)c2)cc1O Show InChI InChI=1S/C22H18N4O6/c27-17-6-4-13(8-19(17)29)11-23-25-21(31)15-2-1-3-16(10-15)22(32)26-24-12-14-5-7-18(28)20(30)9-14/h1-12,27-30H,(H,25,31)(H,26,32)/b23-11+,24-12+	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.92E+4	n/a	n/a	n/a	n/a	n/a	n/a
Kumamoto Health Science University Curated by ChEMBL					Assay Description Inhibition of rat testis GST-tagged PARG catalytic activity after 30 mins using [32P]poly(ADP-ribose) by radioassay				Bioorg Med Chem Lett 24: 3802-6 (2014) Article DOI: 10.1016/j.bmcl.2014.06.065 BindingDB Entry DOI: 10.7270/Q2348N18
					More data for this Ligand-Target Pair
Poly(ADP-ribose) glycohydrolase (Rattus norvegicus)	BDBM50052833 (CHEMBL3318752) Show SMILES Oc1cc(\C=N\NC(=O)CCCC(=O)N\N=C\c2cc(O)c(O)c(O)c2)cc(O)c1O Show InChI InChI=1S/C19H20N4O8/c24-12-4-10(5-13(25)18(12)30)8-20-22-16(28)2-1-3-17(29)23-21-9-11-6-14(26)19(31)15(27)7-11/h4-9,24-27,30-31H,1-3H2,(H,22,28)(H,23,29)/b20-8+,21-9+	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.74E+4	n/a	n/a	n/a	n/a	n/a	n/a
Kumamoto Health Science University Curated by ChEMBL					Assay Description Inhibition of rat testis GST-tagged PARG catalytic activity after 30 mins using [32P]poly(ADP-ribose) by radioassay				Bioorg Med Chem Lett 24: 3802-6 (2014) Article DOI: 10.1016/j.bmcl.2014.06.065 BindingDB Entry DOI: 10.7270/Q2348N18
					More data for this Ligand-Target Pair
DNA topoisomerase 1 (Homo sapiens (Human))	BDBM50142525 (CHEMBL47524 | N-(4,5-Dihydro-thiazol-2-yl)-3,4,5-t...) Show SMILES Oc1cc(cc(O)c1O)C(=O)NC1=NCCS1 |t:13| Show InChI InChI=1S/C10H10N2O4S/c13-6-3-5(4-7(14)8(6)15)9(16)12-10-11-1-2-17-10/h3-4,13-15H,1-2H2,(H,11,12,16)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.44E+4	n/a	n/a	n/a	n/a	n/a	n/a
Kumamoto University Curated by ChEMBL					Assay Description Inhibitory concentration against relaxation activity of DNA topoisomerase I by detecting the conversion of supercoiled pBR322 DNA to its relaxed form				Bioorg Med Chem Lett 14: 1669-72 (2004) Article DOI: 10.1016/j.bmcl.2004.01.060 BindingDB Entry DOI: 10.7270/Q2GX4B0X
					More data for this Ligand-Target Pair
Poly(ADP-ribose) glycohydrolase (Rattus norvegicus)	BDBM50053032 (CHEMBL3318741) Show SMILES Oc1ccc(\C=N\NC(=O)c2cccc(c2)C(=O)N\N=C\c2ccc(O)cc2O)c(O)c1 Show InChI InChI=1S/C22H18N4O6/c27-17-6-4-15(19(29)9-17)11-23-25-21(31)13-2-1-3-14(8-13)22(32)26-24-12-16-5-7-18(28)10-20(16)30/h1-12,27-30H,(H,25,31)(H,26,32)/b23-11+,24-12+	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	4.01E+4	n/a	n/a	n/a	n/a	n/a	n/a
Kumamoto Health Science University Curated by ChEMBL					Assay Description Inhibition of rat testis GST-tagged PARG catalytic activity after 30 mins using [32P]poly(ADP-ribose) by radioassay				Bioorg Med Chem Lett 24: 3802-6 (2014) Article DOI: 10.1016/j.bmcl.2014.06.065 BindingDB Entry DOI: 10.7270/Q2348N18
					More data for this Ligand-Target Pair
DNA topoisomerase 1 (Homo sapiens (Human))	BDBM50142513 (Acetic acid 2-acetoxy-5-[3-(3,4-diacetoxy-benzoyla...) Show SMILES CC(=O)Oc1ccc(cc1OC(C)=O)C(=O)Nc1cccc(NC(=O)c2ccc(OC(C)=O)c(OC(C)=O)c2)c1 Show InChI InChI=1S/C28H24N2O10/c1-15(31)37-23-10-8-19(12-25(23)39-17(3)33)27(35)29-21-6-5-7-22(14-21)30-28(36)20-9-11-24(38-16(2)32)26(13-20)40-18(4)34/h5-14H,1-4H3,(H,29,35)(H,30,36)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.32E+4	n/a	n/a	n/a	n/a	n/a	n/a
Kumamoto University Curated by ChEMBL					Assay Description Inhibitory concentration against relaxation activity of DNA topoisomerase I by detecting the conversion of supercoiled pBR322 DNA to its relaxed form				Bioorg Med Chem Lett 14: 1669-72 (2004) Article DOI: 10.1016/j.bmcl.2004.01.060 BindingDB Entry DOI: 10.7270/Q2GX4B0X
					More data for this Ligand-Target Pair
Signal transducer and activator of transcription 3 (Homo sapiens (Human))	BDBM50338992 (CHEMBL1687978 | N-[5-(2-Furyl)-1,3,4-oxadiazol-2-y...) Show SMILES O=C(Nc1nnc(o1)-c1ccco1)c1cc(nc2ccccc12)-c1cccc2ccccc12 Show InChI InChI=1S/C26H16N4O3/c31-24(28-26-30-29-25(33-26)23-13-6-14-32-23)20-15-22(27-21-12-4-3-10-19(20)21)18-11-5-8-16-7-1-2-9-17(16)18/h1-15H,(H,28,30,31)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of STAT3 transcriptional activity in human HeLa cells by luciferase reporter gene assay				ACS Med Chem Lett 1: 371-375 (2010) Article DOI: 10.1021/ml1000273 BindingDB Entry DOI: 10.7270/Q2FJ2H21
					More data for this Ligand-Target Pair
Signal transducer and activator of transcription 3 (Homo sapiens (Human))	BDBM50338996 (2-(4-Chlorophenyl)-N-(5-phenyl-1,3,4-oxadiazol-2-y...) Show SMILES Clc1ccc(cc1)-c1nnc(NC(=O)c2cc(nc3ccccc23)-c2ccccc2)o1 Show InChI InChI=1S/C24H15ClN4O2/c25-17-12-10-16(11-13-17)23-28-29-24(31-23)27-22(30)19-14-21(15-6-2-1-3-7-15)26-20-9-5-4-8-18(19)20/h1-14H,(H,27,29,30)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of STAT3 transcriptional activity in human HeLa cells by luciferase reporter gene assay				ACS Med Chem Lett 1: 371-375 (2010) Article DOI: 10.1021/ml1000273 BindingDB Entry DOI: 10.7270/Q2FJ2H21
					More data for this Ligand-Target Pair
Signal transducer and activator of transcription 3 (Homo sapiens (Human))	BDBM50338994 (CHEMBL1687976 | N-[5-(2-Furyl)-1,3,4-oxadiazol-2-y...) Show SMILES O=C(Nc1nnc(o1)-c1ccco1)c1cc(nc2ccccc12)-c1cccs1 Show InChI InChI=1S/C20H12N4O3S/c25-18(22-20-24-23-19(27-20)16-7-3-9-26-16)13-11-15(17-8-4-10-28-17)21-14-6-2-1-5-12(13)14/h1-11H,(H,22,24,25)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of STAT3 transcriptional activity in human HeLa cells by luciferase reporter gene assay				ACS Med Chem Lett 1: 371-375 (2010) Article DOI: 10.1021/ml1000273 BindingDB Entry DOI: 10.7270/Q2FJ2H21
					More data for this Ligand-Target Pair
DNA topoisomerase 2-alpha (Homo sapiens (Human))	BDBM50410153 (CHEMBL197216) Show SMILES Oc1cc(\C=C2\C(=O)Oc3ccccc23)cc(O)c1O Show InChI InChI=1S/C15H10O5/c16-11-6-8(7-12(17)14(11)18)5-10-9-3-1-2-4-13(9)20-15(10)19/h1-7,16-18H/b10-5+	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
Kumamoto University Curated by ChEMBL					Assay Description Inhibitory concentration against DNA topoisomerase II activity				Bioorg Med Chem Lett 15: 2065-8 (2005) Article DOI: 10.1016/j.bmcl.2005.02.052 BindingDB Entry DOI: 10.7270/Q2WH2R6D
					More data for this Ligand-Target Pair
Signal transducer and activator of transcription 3 (Homo sapiens (Human))	BDBM50338995 (2-Phenyl-N-(5-phenyl-1,3,4-oxadiazol-2-yl)-4-quino...) Show SMILES O=C(Nc1nnc(o1)-c1ccccc1)c1cc(nc2ccccc12)-c1ccccc1 Show InChI InChI=1S/C24H16N4O2/c29-22(26-24-28-27-23(30-24)17-11-5-2-6-12-17)19-15-21(16-9-3-1-4-10-16)25-20-14-8-7-13-18(19)20/h1-15H,(H,26,28,29)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.60E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of STAT3 transcriptional activity in human HeLa cells by luciferase reporter gene assay				ACS Med Chem Lett 1: 371-375 (2010) Article DOI: 10.1021/ml1000273 BindingDB Entry DOI: 10.7270/Q2FJ2H21
					More data for this Ligand-Target Pair
Signal transducer and activator of transcription 3 (Homo sapiens (Human))	BDBM50338993 (2-(2-Furyl)-N-[5-(2-furyl)-1,3,4-oxadiazol-2-yl]-4...) Show SMILES O=C(Nc1nnc(o1)-c1ccco1)c1cc(nc2ccccc12)-c1ccco1 Show InChI InChI=1S/C20H12N4O4/c25-18(22-20-24-23-19(28-20)17-8-4-10-27-17)13-11-15(16-7-3-9-26-16)21-14-6-2-1-5-12(13)14/h1-11H,(H,22,24,25)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.60E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of STAT3 transcriptional activity in human HeLa cells by luciferase reporter gene assay				ACS Med Chem Lett 1: 371-375 (2010) Article DOI: 10.1021/ml1000273 BindingDB Entry DOI: 10.7270/Q2FJ2H21
					More data for this Ligand-Target Pair
Signal transducer and activator of transcription 3 (Homo sapiens (Human))	BDBM50338998 (CHEMBL1687965 | N-[5-(3-Furyl)-1,3,4-oxadiazol-2-y...) Show SMILES O=C(Nc1nnc(o1)-c1ccoc1)c1cc(nc2ccccc12)-c1ccccc1 Show InChI InChI=1S/C22H14N4O3/c27-20(24-22-26-25-21(29-22)15-10-11-28-13-15)17-12-19(14-6-2-1-3-7-14)23-18-9-5-4-8-16(17)18/h1-13H,(H,24,26,27)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of STAT3 transcriptional activity in human HeLa cells by luciferase reporter gene assay				ACS Med Chem Lett 1: 371-375 (2010) Article DOI: 10.1021/ml1000273 BindingDB Entry DOI: 10.7270/Q2FJ2H21
					More data for this Ligand-Target Pair
Signal transducer and activator of transcription 3 (Homo sapiens (Human))	BDBM50338991 (CHEMBL1687979 | N-[5-(2-Furyl)-1,3,4-oxadiazol-2-y...) Show SMILES O=C(Nc1nnc(o1)-c1ccco1)c1cc(nc2ccccc12)-c1ccccc1 Show InChI InChI=1S/C22H14N4O3/c27-20(24-22-26-25-21(29-22)19-11-6-12-28-19)16-13-18(14-7-2-1-3-8-14)23-17-10-5-4-9-15(16)17/h1-13H,(H,24,26,27)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.40E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of STAT3 transcriptional activity in human HeLa cells by luciferase reporter gene assay				ACS Med Chem Lett 1: 371-375 (2010) Article DOI: 10.1021/ml1000273 BindingDB Entry DOI: 10.7270/Q2FJ2H21
					More data for this Ligand-Target Pair
Poly(ADP-ribose) glycohydrolase (Rattus norvegicus)	BDBM50053038 (CHEMBL3318735) Show SMILES Oc1ccc(\C=N\NC(=O)c2ccc(cc2)C(=O)N\N=C\c2ccc(O)cc2O)c(O)c1 Show InChI InChI=1S/C22H18N4O6/c27-17-7-5-15(19(29)9-17)11-23-25-21(31)13-1-2-14(4-3-13)22(32)26-24-12-16-6-8-18(28)10-20(16)30/h1-12,27-30H,(H,25,31)(H,26,32)/b23-11+,24-12+	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>7.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
Kumamoto Health Science University Curated by ChEMBL					Assay Description Inhibition of rat testis GST-tagged PARG catalytic activity after 30 mins using [32P]poly(ADP-ribose) by radioassay				Bioorg Med Chem Lett 24: 3802-6 (2014) Article DOI: 10.1016/j.bmcl.2014.06.065 BindingDB Entry DOI: 10.7270/Q2348N18
					More data for this Ligand-Target Pair

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