Compile Data Set for Download or QSAR

Found 82 hits with Last Name = 'scholz' and Initial = 'th'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha (Homo sapiens (Human))	BDBM50369371 (CHEMBL1790750) Show SMILES CC[C@@H](C)[C@@H](CN(CC(=O)N[C@@H](CCO)C(O)=O)Cc1cccc2ccccc12)NC[C@@H](N)CS Show InChI InChI=1S/C26H40N4O4S/c1-3-18(2)24(28-13-21(27)17-35)15-30(16-25(32)29-23(11-12-31)26(33)34)14-20-9-6-8-19-7-4-5-10-22(19)20/h4-10,18,21,23-24,28,31,35H,3,11-17,27H2,1-2H3,(H,29,32)(H,33,34)/t18-,21-,23+,24-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.123	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of [3H]FPP incorporation into recombinant human Ha-Ras by Farnesyltransferase				J Med Chem 41: 2651-6 (1998) Article DOI: 10.1021/jm9800907 BindingDB Entry DOI: 10.7270/Q2WW7JCV
					More data for this Ligand-Target Pair
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha (Homo sapiens (Human))	BDBM50366557 (CHEMBL1790748) Show SMILES CC[C@@H](C)[C@@H](CN(CC(=O)N[C@@H](CCSC)C(O)=O)Cc1ccccc1)NC[C@@H](N)CS Show InChI InChI=1S/C23H40N4O3S2/c1-4-17(2)21(25-12-19(24)16-31)14-27(13-18-8-6-5-7-9-18)15-22(28)26-20(23(29)30)10-11-32-3/h5-9,17,19-21,25,31H,4,10-16,24H2,1-3H3,(H,26,28)(H,29,30)/t17-,19-,20+,21-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.20	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of [3H]FPP incorporation into recombinant human Ha-Ras by Farnesyltransferase				J Med Chem 41: 2651-6 (1998) Article DOI: 10.1021/jm9800907 BindingDB Entry DOI: 10.7270/Q2WW7JCV
					More data for this Ligand-Target Pair
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha (Homo sapiens (Human))	BDBM50369364 (CHEMBL1790760) Show SMILES CC[C@@H](C)[C@@H](CN(CC(=O)N[C@@H](CCSC)C(O)=O)Cc1ccccc1)NCCCS Show InChI InChI=1S/C23H39N3O3S2/c1-4-18(2)21(24-12-8-13-30)16-26(15-19-9-6-5-7-10-19)17-22(27)25-20(23(28)29)11-14-31-3/h5-7,9-10,18,20-21,24,30H,4,8,11-17H2,1-3H3,(H,25,27)(H,28,29)/t18-,20+,21-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.20	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of [3H]FPP incorporation into recombinant human Ha-Ras by Farnesyltransferase				J Med Chem 41: 2651-6 (1998) Article DOI: 10.1021/jm9800907 BindingDB Entry DOI: 10.7270/Q2WW7JCV
					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Homo sapiens (Human))	BDBM50044312 (CHEMBL302780 | Fluoro-(octane-1-sulfonyl)-methanes...) Show SMILES CCCCCCCCS(=O)(=O)C(F)S(N)(=O)=O Show InChI InChI=1S/C9H20FNO4S2/c1-2-3-4-5-6-7-8-16(12,13)9(10)17(11,14)15/h9H,2-8H2,1H3,(H2,11,14,15)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description In vitro inhibition of purified human erythrocyte carbonic anhydrase II				J Med Chem 36: 2134-41 (1993) BindingDB Entry DOI: 10.7270/Q2GX49N1
					More data for this Ligand-Target Pair
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha (Homo sapiens (Human))	BDBM50369370 (CHEMBL1790745) Show SMILES CC[C@@H](C)[C@@H](CN[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCSC)C(O)=O)NC[C@@H](N)CS Show InChI InChI=1S/C23H40N4O3S2/c1-4-16(2)21(25-13-18(24)15-31)14-26-20(12-17-8-6-5-7-9-17)22(28)27-19(23(29)30)10-11-32-3/h5-9,16,18-21,25-26,31H,4,10-15,24H2,1-3H3,(H,27,28)(H,29,30)/t16-,18-,19+,20+,21-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.80	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of [3H]FPP incorporation into recombinant human Ha-Ras by Farnesyltransferase				J Med Chem 41: 2651-6 (1998) Article DOI: 10.1021/jm9800907 BindingDB Entry DOI: 10.7270/Q2WW7JCV
					More data for this Ligand-Target Pair
Geranylgeranyl transferase type-1 subunit beta/Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha (Bos taurus (bovine))	BDBM50031179 ((S)-2-((R)-2-Amino-3-mercapto-propylamino)-3-methy...) Show SMILES CCC(C)[C@H](NC[C@@H](N)CS)C(=O)Nc1cccc(C)c1 Show InChI InChI=1S/C16H27N3OS/c1-4-12(3)15(18-9-13(17)10-21)16(20)19-14-7-5-6-11(2)8-14/h5-8,12-13,15,18,21H,4,9-10,17H2,1-3H3,(H,19,20)/t12?,13-,15+/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	6.20	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of bovine Geranylgeranyl transferase type I				J Med Chem 38: 3967-71 (1995) BindingDB Entry DOI: 10.7270/Q2XS5TD4
					More data for this Ligand-Target Pair
Geranylgeranyl transferase type-1 subunit beta/Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha (Bos taurus (bovine))	BDBM50031169 ((S)-2-((R)-2-Amino-3-mercapto-propylamino)-3-methy...) Show SMILES CCC(C)[C@H](NC[C@@H](N)CS)C(=O)NCc1cccc(Cl)c1Cl Show InChI InChI=1S/C16H25Cl2N3OS/c1-3-10(2)15(20-8-12(19)9-23)16(22)21-7-11-5-4-6-13(17)14(11)18/h4-6,10,12,15,20,23H,3,7-9,19H2,1-2H3,(H,21,22)/t10?,12-,15+/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	6.80	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of bovine Geranylgeranyl transferase type I				J Med Chem 38: 3967-71 (1995) BindingDB Entry DOI: 10.7270/Q2XS5TD4
					More data for this Ligand-Target Pair
Geranylgeranyl transferase type-1 subunit beta/Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha (Bos taurus (bovine))	BDBM50031167 ((S)-2-((R)-2-Amino-3-mercapto-propylamino)-3-methy...) Show SMILES CCC(C)[C@H](NC[C@@H](N)CS)C(=O)Nc1cccc(C)c1C Show InChI InChI=1S/C17H29N3OS/c1-5-11(2)16(19-9-14(18)10-22)17(21)20-15-8-6-7-12(3)13(15)4/h6-8,11,14,16,19,22H,5,9-10,18H2,1-4H3,(H,20,21)/t11?,14-,16+/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	8.20	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of bovine Geranylgeranyl transferase type I				J Med Chem 38: 3967-71 (1995) BindingDB Entry DOI: 10.7270/Q2XS5TD4
					More data for this Ligand-Target Pair
Geranylgeranyl transferase type-1 subunit beta/Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha (Bos taurus (bovine))	BDBM50031170 ((S)-2-((R)-2-Amino-3-mercapto-propylamino)-3-methy...) Show SMILES CCC(C)[C@H](NC[C@@H](N)CS)C(=O)NCc1ccc(Cl)cc1Cl Show InChI InChI=1S/C16H25Cl2N3OS/c1-3-10(2)15(20-8-13(19)9-23)16(22)21-7-11-4-5-12(17)6-14(11)18/h4-6,10,13,15,20,23H,3,7-9,19H2,1-2H3,(H,21,22)/t10?,13-,15+/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of bovine Geranylgeranyl transferase type I				J Med Chem 38: 3967-71 (1995) BindingDB Entry DOI: 10.7270/Q2XS5TD4
					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Homo sapiens (Human))	BDBM10880 (AZA | AZA2 | AZM acetazolamide | Acerazolamide, AA...) Show SMILES CC(=O)Nc1nnc(s1)S(N)(=O)=O Show InChI InChI=1S/C4H6N4O3S2/c1-2(9)6-3-7-8-4(12-3)13(5,10)11/h1H3,(H2,5,10,11)(H,6,7,9)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank MMDB PDB PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description In vitro inhibition of purified human erythrocyte carbonic anhydrase II				J Med Chem 36: 2134-41 (1993) BindingDB Entry DOI: 10.7270/Q2GX49N1
					More data for this Ligand-Target Pair				3D Structure (crystal)
Geranylgeranyl transferase type-1 subunit beta/Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha (Bos taurus (bovine))	BDBM50369371 (CHEMBL1790750) Show SMILES CC[C@@H](C)[C@@H](CN(CC(=O)N[C@@H](CCO)C(O)=O)Cc1cccc2ccccc12)NC[C@@H](N)CS Show InChI InChI=1S/C26H40N4O4S/c1-3-18(2)24(28-13-21(27)17-35)15-30(16-25(32)29-23(11-12-31)26(33)34)14-20-9-6-8-19-7-4-5-10-22(19)20/h4-10,18,21,23-24,28,31,35H,3,11-17,27H2,1-2H3,(H,29,32)(H,33,34)/t18-,21-,23+,24-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of bovine Geranylgeranyl transferase type I				J Med Chem 41: 2651-6 (1998) Article DOI: 10.1021/jm9800907 BindingDB Entry DOI: 10.7270/Q2WW7JCV
					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Homo sapiens (Human))	BDBM50044313 (CHEMBL304131 | Chloro-(octane-1-sulfonyl)-methanes...) Show SMILES CCCCCCCCS(=O)(=O)C(Cl)S(N)(=O)=O Show InChI InChI=1S/C9H20ClNO4S2/c1-2-3-4-5-6-7-8-16(12,13)9(10)17(11,14)15/h9H,2-8H2,1H3,(H2,11,14,15)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description In vitro inhibition of purified human erythrocyte carbonic anhydrase II				J Med Chem 36: 2134-41 (1993) BindingDB Entry DOI: 10.7270/Q2GX49N1
					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Homo sapiens (Human))	BDBM50044311 (CHEMBL67511 | TRIFLUOROMETHANE SULFONAMIDE | Trifl...) Show SMILES NS(=O)(=O)C(F)(F)F Show InChI InChI=1S/CH2F3NO2S/c2-1(3,4)8(5,6)7/h(H2,5,6,7)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents	MMDB PubMed	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description In vitro inhibition of purified human erythrocyte carbonic anhydrase II				J Med Chem 36: 2134-41 (1993) BindingDB Entry DOI: 10.7270/Q2GX49N1
					More data for this Ligand-Target Pair				3D Structure (docked)
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha (Homo sapiens (Human))	BDBM50407296 (CHEMBL2052018 | L-731735) Show SMILES CC[C@H](C)[C@@H](CN[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CCO)C(O)=O)NC[C@@H](N)CS Show InChI InChI=1S/C19H40N4O4S/c1-5-12(3)16(21-9-14(20)11-28)10-22-17(13(4)6-2)18(25)23-15(7-8-24)19(26)27/h12-17,21-22,24,28H,5-11,20H2,1-4H3,(H,23,25)(H,26,27)/t12-,13-,14+,15-,16+,17-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL MCE KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of [3H]FPP incorporation into recombinant human Ha-Ras by Farnesyltransferase				J Med Chem 41: 2651-6 (1998) Article DOI: 10.1021/jm9800907 BindingDB Entry DOI: 10.7270/Q2WW7JCV
					More data for this Ligand-Target Pair
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha (Homo sapiens (Human))	BDBM50369368 (CHEMBL1790744) Show SMILES CCC[C@H](N(C)C[C@@H](NC[C@@H](N)CS)[C@H](C)CC)C(=O)N[C@@H](CCO)C(O)=O Show InChI InChI=1S/C19H40N4O4S/c1-5-7-17(18(25)22-15(8-9-24)19(26)27)23(4)11-16(13(3)6-2)21-10-14(20)12-28/h13-17,21,24,28H,5-12,20H2,1-4H3,(H,22,25)(H,26,27)/t13-,14-,15+,16-,17+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	21	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of [3H]FPP incorporation into recombinant human Ha-Ras by Farnesyltransferase				J Med Chem 41: 2651-6 (1998) Article DOI: 10.1021/jm9800907 BindingDB Entry DOI: 10.7270/Q2WW7JCV
					More data for this Ligand-Target Pair
Geranylgeranyl transferase type-1 subunit beta/Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha (Bos taurus (bovine))	BDBM50031168 ((S)-2-((R)-2-Amino-3-mercapto-propylamino)-3-methy...) Show SMILES CCC(C)[C@H](NC[C@@H](N)CS)C(=O)NCc1ccc(cc1)S(N)(=O)=O Show InChI InChI=1S/C16H28N4O3S2/c1-3-11(2)15(19-9-13(17)10-24)16(21)20-8-12-4-6-14(7-5-12)25(18,22)23/h4-7,11,13,15,19,24H,3,8-10,17H2,1-2H3,(H,20,21)(H2,18,22,23)/t11?,13-,15+/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	21	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of bovine Geranylgeranyl transferase type I				J Med Chem 38: 3967-71 (1995) BindingDB Entry DOI: 10.7270/Q2XS5TD4
					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Homo sapiens (Human))	BDBM50044309 ((Octane-1-sulfonyl)-methanesulfonamide | CHEMBL421...) Show SMILES CCCCCCCCS(=O)(=O)CS(N)(=O)=O Show InChI InChI=1S/C9H21NO4S2/c1-2-3-4-5-6-7-8-15(11,12)9-16(10,13)14/h2-9H2,1H3,(H2,10,13,14)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	22	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description In vitro inhibition of purified human erythrocyte carbonic anhydrase II				J Med Chem 36: 2134-41 (1993) BindingDB Entry DOI: 10.7270/Q2GX49N1
					More data for this Ligand-Target Pair
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha (Bos taurus (bovine))	BDBM50031169 ((S)-2-((R)-2-Amino-3-mercapto-propylamino)-3-methy...) Show SMILES CCC(C)[C@H](NC[C@@H](N)CS)C(=O)NCc1cccc(Cl)c1Cl Show InChI InChI=1S/C16H25Cl2N3OS/c1-3-10(2)15(20-8-12(19)9-23)16(22)21-7-11-5-4-6-13(17)14(11)18/h4-6,10,12,15,20,23H,3,7-9,19H2,1-2H3,(H,21,22)/t10?,12-,15+/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	23	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description In vitro concentration required to reduce Farnesyltransferase catalyzed incorporation of [3H]-FPP into recombinant Ha-Ras protein by 50%				J Med Chem 38: 3967-71 (1995) BindingDB Entry DOI: 10.7270/Q2XS5TD4
					More data for this Ligand-Target Pair
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha (Homo sapiens (Human))	BDBM50369372 (CHEMBL1790756) Show SMILES CC[C@@H](C)[C@@H](CN(C)[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CCSC)C(O)=O)NC[C@@H](N)CS Show InChI InChI=1S/C21H44N4O3S2/c1-7-14(3)18(23-11-16(22)13-29)12-25(5)19(15(4)8-2)20(26)24-17(21(27)28)9-10-30-6/h14-19,23,29H,7-13,22H2,1-6H3,(H,24,26)(H,27,28)/t14-,15+,16-,17+,18-,19+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	25	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of [3H]FPP incorporation into recombinant human Ha-Ras by Farnesyltransferase				J Med Chem 41: 2651-6 (1998) Article DOI: 10.1021/jm9800907 BindingDB Entry DOI: 10.7270/Q2WW7JCV
					More data for this Ligand-Target Pair
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha (Bos taurus (bovine))	BDBM50369366 (CHEMBL1790752) Show SMILES CC[C@@H](C)[C@@H](CN[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCO)C(O)=O)NC[C@@H](N)CS Show InChI InChI=1S/C22H38N4O4S/c1-3-15(2)20(24-12-17(23)14-31)13-25-19(11-16-7-5-4-6-8-16)21(28)26-18(9-10-27)22(29)30/h4-8,15,17-20,24-25,27,31H,3,9-14,23H2,1-2H3,(H,26,28)(H,29,30)/t15-,17-,18+,19+,20-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	26	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of bovine brain Farnesyltransferase at 1 nM				J Med Chem 41: 2651-6 (1998) Article DOI: 10.1021/jm9800907 BindingDB Entry DOI: 10.7270/Q2WW7JCV
					More data for this Ligand-Target Pair
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha (Bos taurus (bovine))	BDBM50369375 (CHEMBL1790753) Show SMILES CCC[C@H](NC[C@@H](NC[C@@H](N)CS)[C@H](C)CC)C(=O)N[C@@H](CCO)C(O)=O Show InChI InChI=1S/C18H38N4O4S/c1-4-6-14(17(24)22-15(7-8-23)18(25)26)21-10-16(12(3)5-2)20-9-13(19)11-27/h12-16,20-21,23,27H,4-11,19H2,1-3H3,(H,22,24)(H,25,26)/t12-,13-,14+,15+,16-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	27	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of bovine brain Farnesyltransferase at 10 pM				J Med Chem 41: 2651-6 (1998) Article DOI: 10.1021/jm9800907 BindingDB Entry DOI: 10.7270/Q2WW7JCV
					More data for this Ligand-Target Pair
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha (Homo sapiens (Human))	BDBM50369367 (CHEMBL1790757) Show SMILES CC[C@@H](C)[C@@H](CN[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CCSC)C(O)=O)NC[C@@H](N)CS Show InChI InChI=1S/C20H42N4O3S2/c1-6-13(3)17(22-10-15(21)12-28)11-23-18(14(4)7-2)19(25)24-16(20(26)27)8-9-29-5/h13-18,22-23,28H,6-12,21H2,1-5H3,(H,24,25)(H,26,27)/t13-,14+,15-,16+,17-,18+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of [3H]FPP incorporation into recombinant human Ha-Ras by Farnesyltransferase				J Med Chem 41: 2651-6 (1998) Article DOI: 10.1021/jm9800907 BindingDB Entry DOI: 10.7270/Q2WW7JCV
					More data for this Ligand-Target Pair
Geranylgeranyl transferase type-1 subunit beta/Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha (Bos taurus (bovine))	BDBM50031178 ((S)-2-((R)-2-Amino-3-mercapto-propylamino)-3-methy...) Show SMILES CCC(C)[C@H](NC[C@@H](N)CS)C(=O)NCc1ccc(C)cc1C Show InChI InChI=1S/C18H31N3OS/c1-5-13(3)17(20-10-16(19)11-23)18(22)21-9-15-7-6-12(2)8-14(15)4/h6-8,13,16-17,20,23H,5,9-11,19H2,1-4H3,(H,21,22)/t13?,16-,17+/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of bovine Geranylgeranyl transferase type I				J Med Chem 38: 3967-71 (1995) BindingDB Entry DOI: 10.7270/Q2XS5TD4
					More data for this Ligand-Target Pair
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha (Bos taurus (bovine))	BDBM50031167 ((S)-2-((R)-2-Amino-3-mercapto-propylamino)-3-methy...) Show SMILES CCC(C)[C@H](NC[C@@H](N)CS)C(=O)Nc1cccc(C)c1C Show InChI InChI=1S/C17H29N3OS/c1-5-11(2)16(19-9-14(18)10-22)17(21)20-15-8-6-7-12(3)13(15)4/h6-8,11,14,16,19,22H,5,9-10,18H2,1-4H3,(H,20,21)/t11?,14-,16+/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description In vitro concentration required to reduce Farnesyltransferase catalyzed incorporation of [3H]-FPP into recombinant Ha-Ras protein by 50%				J Med Chem 38: 3967-71 (1995) BindingDB Entry DOI: 10.7270/Q2XS5TD4
					More data for this Ligand-Target Pair
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha (Homo sapiens (Human))	BDBM50369363 (CHEMBL1790747) Show SMILES CC[C@@H](C)[C@@H](CN(C)[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCSC)C(O)=O)NC[C@@H](N)CS Show InChI InChI=1S/C24H42N4O3S2/c1-5-17(2)21(26-14-19(25)16-32)15-28(3)22(13-18-9-7-6-8-10-18)23(29)27-20(24(30)31)11-12-33-4/h6-10,17,19-22,26,32H,5,11-16,25H2,1-4H3,(H,27,29)(H,30,31)/t17-,19-,20+,21-,22+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	42	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of [3H]FPP incorporation into recombinant human Ha-Ras by Farnesyltransferase				J Med Chem 41: 2651-6 (1998) Article DOI: 10.1021/jm9800907 BindingDB Entry DOI: 10.7270/Q2WW7JCV
					More data for this Ligand-Target Pair
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha (Bos taurus (bovine))	BDBM50031179 ((S)-2-((R)-2-Amino-3-mercapto-propylamino)-3-methy...) Show SMILES CCC(C)[C@H](NC[C@@H](N)CS)C(=O)Nc1cccc(C)c1 Show InChI InChI=1S/C16H27N3OS/c1-4-12(3)15(18-9-13(17)10-21)16(20)19-14-7-5-6-11(2)8-14/h5-8,12-13,15,18,21H,4,9-10,17H2,1-3H3,(H,19,20)/t12?,13-,15+/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	46	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description In vitro concentration required to reduce Farnesyltransferase catalyzed incorporation of [3H]-FPP into recombinant Ha-Ras protein by 50%				J Med Chem 38: 3967-71 (1995) BindingDB Entry DOI: 10.7270/Q2XS5TD4
					More data for this Ligand-Target Pair
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha (Bos taurus (bovine))	BDBM50031175 ((S)-2-((R)-2-Amino-3-mercapto-propylamino)-3-methy...) Show SMILES CCC(C)[C@H](NC[C@@H](N)CS)C(=O)Nc1ccc(C)cc1C Show InChI InChI=1S/C17H29N3OS/c1-5-12(3)16(19-9-14(18)10-22)17(21)20-15-7-6-11(2)8-13(15)4/h6-8,12,14,16,19,22H,5,9-10,18H2,1-4H3,(H,20,21)/t12?,14-,16+/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	60	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description In vitro concentration required to reduce Farnesyltransferase catalyzed incorporation of [3H]-FPP into recombinant Ha-Ras protein by 50%				J Med Chem 38: 3967-71 (1995) BindingDB Entry DOI: 10.7270/Q2XS5TD4
					More data for this Ligand-Target Pair
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha (Bos taurus (bovine))	BDBM50031176 ((S)-2-((R)-2-Amino-3-mercapto-propylamino)-3-methy...) Show SMILES CCC(C)[C@H](NC[C@@H](N)CS)C(=O)Nc1ccccc1 Show InChI InChI=1S/C15H25N3OS/c1-3-11(2)14(17-9-12(16)10-20)15(19)18-13-7-5-4-6-8-13/h4-8,11-12,14,17,20H,3,9-10,16H2,1-2H3,(H,18,19)/t11?,12-,14+/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	70	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description In vitro concentration required to reduce Farnesyltransferase catalyzed incorporation of [3H]-FPP into recombinant Ha-Ras protein by 50%				J Med Chem 38: 3967-71 (1995) BindingDB Entry DOI: 10.7270/Q2XS5TD4
					More data for this Ligand-Target Pair
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha (Bos taurus (bovine))	BDBM50369365 (CHEMBL1790754) Show SMILES CC[C@@H](C)[C@@H](CN(C)CC(=O)N[C@@H](CCO)C(O)=O)NC[C@@H](N)CS Show InChI InChI=1S/C16H34N4O4S/c1-4-11(2)14(18-7-12(17)10-25)8-20(3)9-15(22)19-13(5-6-21)16(23)24/h11-14,18,21,25H,4-10,17H2,1-3H3,(H,19,22)(H,23,24)/t11-,12-,13+,14-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	83	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of bovine brain Farnesyltransferase at 10 pM				J Med Chem 41: 2651-6 (1998) Article DOI: 10.1021/jm9800907 BindingDB Entry DOI: 10.7270/Q2WW7JCV
					More data for this Ligand-Target Pair
Geranylgeranyl transferase type-1 subunit beta/Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha (Bos taurus (bovine))	BDBM50031162 ((S)-2-((R)-2-Amino-3-mercapto-propylamino)-3-methy...) Show SMILES CCC(C)[C@H](NC[C@@H](N)CS)C(=O)NCc1ccccc1 Show InChI InChI=1S/C16H27N3OS/c1-3-12(2)15(18-10-14(17)11-21)16(20)19-9-13-7-5-4-6-8-13/h4-8,12,14-15,18,21H,3,9-11,17H2,1-2H3,(H,19,20)/t12?,14-,15+/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	86	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of bovine Geranylgeranyl transferase type I				J Med Chem 38: 3967-71 (1995) BindingDB Entry DOI: 10.7270/Q2XS5TD4
					More data for this Ligand-Target Pair
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha (Bos taurus (bovine))	BDBM50031170 ((S)-2-((R)-2-Amino-3-mercapto-propylamino)-3-methy...) Show SMILES CCC(C)[C@H](NC[C@@H](N)CS)C(=O)NCc1ccc(Cl)cc1Cl Show InChI InChI=1S/C16H25Cl2N3OS/c1-3-10(2)15(20-8-13(19)9-23)16(22)21-7-11-4-5-12(17)6-14(11)18/h4-6,10,13,15,20,23H,3,7-9,19H2,1-2H3,(H,21,22)/t10?,13-,15+/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	97	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description In vitro concentration required to reduce Farnesyltransferase catalyzed incorporation of [3H]-FPP into recombinant Ha-Ras protein by 50%				J Med Chem 38: 3967-71 (1995) BindingDB Entry DOI: 10.7270/Q2XS5TD4
					More data for this Ligand-Target Pair
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha (Mus musculus)	BDBM50065394 ((S)-2-(2-{[(S)-2-((R)-2-Amino-3-mercapto-propylami...) Show SMILES CCC(C)[C@@H](CN(CC(=O)N[C@@H](CCSC)C(=O)OC)Cc1ccccc1)NC[C@@H](N)CS Show InChI InChI=1S/C24H42N4O3S2/c1-5-18(2)22(26-13-20(25)17-32)15-28(14-19-9-7-6-8-10-19)16-23(29)27-21(11-12-33-4)24(30)31-3/h6-10,18,20-22,26,32H,5,11-17,25H2,1-4H3,(H,27,29)/t18?,20-,21+,22-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of post-translational processing of v-Ras protein in NIH3T3 cells				J Med Chem 41: 2651-6 (1998) Article DOI: 10.1021/jm9800907 BindingDB Entry DOI: 10.7270/Q2WW7JCV
					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Homo sapiens (Human))	BDBM50044317 ((2-Phenyl-ethanesulfonyl)-methanesulfonamide | CHE...) Show SMILES NS(=O)(=O)CS(=O)(=O)CCc1ccccc1 Show InChI InChI=1S/C9H13NO4S2/c10-16(13,14)8-15(11,12)7-6-9-4-2-1-3-5-9/h1-5H,6-8H2,(H2,10,13,14)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description In vitro inhibition of purified human erythrocyte carbonic anhydrase II				J Med Chem 36: 2134-41 (1993) BindingDB Entry DOI: 10.7270/Q2GX49N1
					More data for this Ligand-Target Pair
Geranylgeranyl transferase type-1 subunit beta/Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha (Bos taurus (bovine))	BDBM50031163 ((S)-2-((R)-2-Amino-3-mercapto-propylamino)-3-methy...) Show SMILES CCC(C)[C@H](NC[C@@H](N)CS)C(=O)NCCC(C)C Show InChI InChI=1S/C14H31N3OS/c1-5-11(4)13(17-8-12(15)9-19)14(18)16-7-6-10(2)3/h10-13,17,19H,5-9,15H2,1-4H3,(H,16,18)/t11?,12-,13+/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of bovine Geranylgeranyl transferase type I				J Med Chem 38: 3967-71 (1995) BindingDB Entry DOI: 10.7270/Q2XS5TD4
					More data for this Ligand-Target Pair
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha (Homo sapiens (Human))	BDBM50369369 (CHEMBL1790759) Show SMILES CC[C@@H](C)[C@@H](CN(CC(=O)N[C@@H](CCSC)C(O)=O)Cc1ccccc1)NC(=O)CCS Show InChI InChI=1S/C23H37N3O4S2/c1-4-17(2)20(25-21(27)10-12-31)15-26(14-18-8-6-5-7-9-18)16-22(28)24-19(23(29)30)11-13-32-3/h5-9,17,19-20,31H,4,10-16H2,1-3H3,(H,24,28)(H,25,27)(H,29,30)/t17-,19+,20-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	110	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of [3H]-FPP incorporation into recombinant human Ha-Ras by Farnesyltransferase				J Med Chem 41: 2651-6 (1998) Article DOI: 10.1021/jm9800907 BindingDB Entry DOI: 10.7270/Q2WW7JCV
					More data for this Ligand-Target Pair
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha (Bos taurus (bovine))	BDBM50031178 ((S)-2-((R)-2-Amino-3-mercapto-propylamino)-3-methy...) Show SMILES CCC(C)[C@H](NC[C@@H](N)CS)C(=O)NCc1ccc(C)cc1C Show InChI InChI=1S/C18H31N3OS/c1-5-13(3)17(20-10-16(19)11-23)18(22)21-9-15-7-6-12(2)8-14(15)4/h6-8,13,16-17,20,23H,5,9-11,19H2,1-4H3,(H,21,22)/t13?,16-,17+/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	120	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description In vitro concentration required to reduce Farnesyltransferase catalyzed incorporation of [3H]-FPP into recombinant Ha-Ras protein by 50%				J Med Chem 38: 3967-71 (1995) BindingDB Entry DOI: 10.7270/Q2XS5TD4
					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Homo sapiens (Human))	BDBM50044320 ((3-Phenyl-propane-1-sulfonyl)-methanesulfonamide |...) Show SMILES NS(=O)(=O)CS(=O)(=O)CCCc1ccccc1 Show InChI InChI=1S/C10H15NO4S2/c11-17(14,15)9-16(12,13)8-4-7-10-5-2-1-3-6-10/h1-3,5-6H,4,7-9H2,(H2,11,14,15)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	190	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description In vitro inhibition of purified human erythrocyte carbonic anhydrase II				J Med Chem 36: 2134-41 (1993) BindingDB Entry DOI: 10.7270/Q2GX49N1
					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Homo sapiens (Human))	BDBM50044310 (CHEMBL68840 | Dichloro-(octane-1-sulfonyl)-methane...) Show SMILES CCCCCCCCS(=O)(=O)C(Cl)(Cl)S(N)(=O)=O Show InChI InChI=1S/C9H19Cl2NO4S2/c1-2-3-4-5-6-7-8-17(13,14)9(10,11)18(12,15)16/h2-8H2,1H3,(H2,12,15,16)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description In vitro inhibition of purified human erythrocyte carbonic anhydrase II				J Med Chem 36: 2134-41 (1993) BindingDB Entry DOI: 10.7270/Q2GX49N1
					More data for this Ligand-Target Pair
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha (Bos taurus (bovine))	BDBM50031177 ((S)-2-((R)-2-Amino-3-mercapto-propylamino)-3-methy...) Show SMILES CCC(C)[C@H](NC[C@@H](N)CS)C(=O)NCCCc1ccccc1 Show InChI InChI=1S/C18H31N3OS/c1-3-14(2)17(21-12-16(19)13-23)18(22)20-11-7-10-15-8-5-4-6-9-15/h4-6,8-9,14,16-17,21,23H,3,7,10-13,19H2,1-2H3,(H,20,22)/t14?,16-,17+/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	350	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description In vitro concentration required to reduce Farnesyltransferase catalyzed incorporation of [3H]-FPP into recombinant Ha-Ras protein by 50%				J Med Chem 38: 3967-71 (1995) BindingDB Entry DOI: 10.7270/Q2XS5TD4
					More data for this Ligand-Target Pair
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha (Bos taurus (bovine))	BDBM50031160 ((S)-2-((R)-2-Amino-3-mercapto-propylamino)-3-methy...) Show SMILES CCC(C)[C@H](NC[C@@H](N)CS)C(=O)NC(CO)Cc1ccccc1 Show InChI InChI=1S/C18H31N3O2S/c1-3-13(2)17(20-10-15(19)12-24)18(23)21-16(11-22)9-14-7-5-4-6-8-14/h4-8,13,15-17,20,22,24H,3,9-12,19H2,1-2H3,(H,21,23)/t13?,15-,16?,17+/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	370	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description In vitro concentration required to reduce Farnesyltransferase catalyzed incorporation of [3H]-FPP into recombinant Ha-Ras protein by 50%				J Med Chem 38: 3967-71 (1995) BindingDB Entry DOI: 10.7270/Q2XS5TD4
					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Homo sapiens (Human))	BDBM50044322 ((4-Hydroxy-benzenesulfonyl)-methanesulfonamide | C...) Show SMILES NS(=O)(=O)CS(=O)(=O)c1ccc(O)cc1 Show InChI InChI=1S/C7H9NO5S2/c8-15(12,13)5-14(10,11)7-3-1-6(9)2-4-7/h1-4,9H,5H2,(H2,8,12,13)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	PubMed	n/a	n/a	400	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description In vitro inhibition of purified human erythrocyte carbonic anhydrase II				J Med Chem 36: 2134-41 (1993) BindingDB Entry DOI: 10.7270/Q2GX49N1
					More data for this Ligand-Target Pair
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha (Bos taurus (bovine))	BDBM50031168 ((S)-2-((R)-2-Amino-3-mercapto-propylamino)-3-methy...) Show SMILES CCC(C)[C@H](NC[C@@H](N)CS)C(=O)NCc1ccc(cc1)S(N)(=O)=O Show InChI InChI=1S/C16H28N4O3S2/c1-3-11(2)15(19-9-13(17)10-24)16(21)20-8-12-4-6-14(7-5-12)25(18,22)23/h4-7,11,13,15,19,24H,3,8-10,17H2,1-2H3,(H,20,21)(H2,18,22,23)/t11?,13-,15+/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	400	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description In vitro concentration required to reduce Farnesyltransferase catalyzed incorporation of [3H]-FPP into recombinant Ha-Ras protein by 50%				J Med Chem 38: 3967-71 (1995) BindingDB Entry DOI: 10.7270/Q2XS5TD4
					More data for this Ligand-Target Pair
Geranylgeranyl transferase type-1 subunit beta/Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha (Bos taurus (bovine))	BDBM50366557 (CHEMBL1790748) Show SMILES CC[C@@H](C)[C@@H](CN(CC(=O)N[C@@H](CCSC)C(O)=O)Cc1ccccc1)NC[C@@H](N)CS Show InChI InChI=1S/C23H40N4O3S2/c1-4-17(2)21(25-12-19(24)16-31)14-27(13-18-8-6-5-7-9-18)15-22(28)26-20(23(29)30)10-11-32-3/h5-9,17,19-21,25,31H,4,10-16,24H2,1-3H3,(H,26,28)(H,29,30)/t17-,19-,20+,21-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	450	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of bovine Geranylgeranyl transferase type I				J Med Chem 41: 2651-6 (1998) Article DOI: 10.1021/jm9800907 BindingDB Entry DOI: 10.7270/Q2WW7JCV
					More data for this Ligand-Target Pair
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha (Bos taurus (bovine))	BDBM50031162 ((S)-2-((R)-2-Amino-3-mercapto-propylamino)-3-methy...) Show SMILES CCC(C)[C@H](NC[C@@H](N)CS)C(=O)NCc1ccccc1 Show InChI InChI=1S/C16H27N3OS/c1-3-12(2)15(18-10-14(17)11-21)16(20)19-9-13-7-5-4-6-8-13/h4-8,12,14-15,18,21H,3,9-11,17H2,1-2H3,(H,19,20)/t12?,14-,15+/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	450	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description In vitro concentration required to reduce Farnesyltransferase catalyzed incorporation of [3H]-FPP into recombinant Ha-Ras protein by 50%				J Med Chem 38: 3967-71 (1995) BindingDB Entry DOI: 10.7270/Q2XS5TD4
					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Homo sapiens (Human))	BDBM50044316 (CHEMBL66465 | Octylsulfanyl-methanesulfonamide) Show SMILES CCCCCCCCSCS(N)(=O)=O Show InChI InChI=1S/C9H21NO2S2/c1-2-3-4-5-6-7-8-13-9-14(10,11)12/h2-9H2,1H3,(H2,10,11,12)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	PubMed	n/a	n/a	480	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description In vitro inhibition of purified human erythrocyte carbonic anhydrase II				J Med Chem 36: 2134-41 (1993) BindingDB Entry DOI: 10.7270/Q2GX49N1
					More data for this Ligand-Target Pair
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha (Mus musculus)	BDBM50369376 (CHEMBL1790751) Show SMILES CC[C@@H](C)[C@@H](CN(CC(=O)N[C@@H](CCSC)C(=O)OC)Cc1cccc2ccccc12)NC[C@@H](N)CS Show InChI InChI=1S/C28H44N4O3S2/c1-5-20(2)26(30-15-23(29)19-36)17-32(16-22-11-8-10-21-9-6-7-12-24(21)22)18-27(33)31-25(13-14-37-4)28(34)35-3/h6-12,20,23,25-26,30,36H,5,13-19,29H2,1-4H3,(H,31,33)/t20-,23-,25+,26-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	500	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of post-translational processing of v-Ras protein in NIH3T3 cells				J Med Chem 41: 2651-6 (1998) Article DOI: 10.1021/jm9800907 BindingDB Entry DOI: 10.7270/Q2WW7JCV
					More data for this Ligand-Target Pair
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha (Bos taurus (bovine))	BDBM50031173 ((S)-2-((R)-2-Amino-3-mercapto-propylamino)-pentano...) Show SMILES CCC[C@H](NC[C@@H](N)CS)C(=O)NCc1ccccc1 Show InChI InChI=1S/C15H25N3OS/c1-2-6-14(17-10-13(16)11-20)15(19)18-9-12-7-4-3-5-8-12/h3-5,7-8,13-14,17,20H,2,6,9-11,16H2,1H3,(H,18,19)/t13-,14+/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	600	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description In vitro concentration required to reduce Farnesyltransferase catalyzed incorporation of [3H]-FPP into recombinant Ha-Ras protein by 50%				J Med Chem 38: 3967-71 (1995) BindingDB Entry DOI: 10.7270/Q2XS5TD4
					More data for this Ligand-Target Pair
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha (Bos taurus (bovine))	BDBM50031183 ((S)-2-((R)-2-Amino-3-mercapto-propylamino)-3-methy...) Show SMILES CCC(C)[C@H](NC[C@@H](N)CS)C(=O)NCc1ccc(OC)cc1 Show InChI InChI=1S/C17H29N3O2S/c1-4-12(2)16(19-10-14(18)11-23)17(21)20-9-13-5-7-15(22-3)8-6-13/h5-8,12,14,16,19,23H,4,9-11,18H2,1-3H3,(H,20,21)/t12?,14-,16+/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	660	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description In vitro concentration required to reduce Farnesyltransferase catalyzed incorporation of [3H]-FPP into recombinant Ha-Ras protein by 50%				J Med Chem 38: 3967-71 (1995) BindingDB Entry DOI: 10.7270/Q2XS5TD4
					More data for this Ligand-Target Pair
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha (Bos taurus (bovine))	BDBM50031172 ((S)-2-((R)-2-Amino-3-mercapto-propylamino)-3-methy...) Show SMILES CCC(C)[C@H](NC[C@@H](N)CS)C(=O)NCCc1ccccc1 Show InChI InChI=1S/C17H29N3OS/c1-3-13(2)16(20-11-15(18)12-22)17(21)19-10-9-14-7-5-4-6-8-14/h4-8,13,15-16,20,22H,3,9-12,18H2,1-2H3,(H,19,21)/t13?,15-,16+/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	707	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description In vitro concentration required to reduce Farnesyltransferase catalyzed incorporation of [3H]-FPP into recombinant Ha-Ras protein by 50%				J Med Chem 38: 3967-71 (1995) BindingDB Entry DOI: 10.7270/Q2XS5TD4
					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Homo sapiens (Human))	BDBM50044319 (6-Methoxy-1,1-dioxo-2,3-dihydro-1H-1lambda*6*-benz...) Show SMILES COc1ccc2CC(S(N)(=O)=O)S(=O)(=O)c2c1 Show InChI InChI=1S/C9H11NO5S2/c1-15-7-3-2-6-4-9(17(10,13)14)16(11,12)8(6)5-7/h2-3,5,9H,4H2,1H3,(H2,10,13,14)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	PubMed	n/a	n/a	800	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description In vitro inhibition of purified human erythrocyte carbonic anhydrase II				J Med Chem 36: 2134-41 (1993) BindingDB Entry DOI: 10.7270/Q2GX49N1
					More data for this Ligand-Target Pair

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